Dr. Salman Ahmed

Antiemetic activity of acalypha fimbriata schumach. & thonn., acalypha ornata hochst., and acalypha wilkesiana cv. godseffiana muell arg

• Authors Details :  
• Tehseen Quds,  
• Salman Ahmed,  
• Muhammad Shaiq Ali,  
• Patrricia Akpomedaye Onocha ,  
• Iqbal Azhar

260 Views Original Article

The current study was designed to explore the antiemetic effect of the methanolic extracts of Acalypha fimbriata Schumach. & Thonn., Acalypha ornata Hochst., and Acalypha wilkesiana cv. godseffiana Muell Arg., aerial parts using chick emesis model to validate their folk use in G.I. disorders. Emesis was induced by the oral administration of copper sulfate to male chicks. All the extracts (150 mg/kg orally) showed an antiemetic effect and were compared with the reference drug chlorpromazine. Among all the extracts, Acalypha ornata Hochst., leaves extract showed the highest (94.51%) and Acalypha fimbriata Schumach. & Thonn., stem extract showed the lowest (35.04%) antiemetic effect.

Article Subject Details

• Perioperative medicine
• Pharmacognosy
• Pharmacology
• Pharmacology and toxicology
• Pharmacy
• Pharmacy practice
• Research

Article Keywords Details

• chlorpromazine
• Acalypha
• Anti-emetic
• Copper sulfate induced vomiting
• Pharmacognosy
• Pharmacology
• Pharmacy

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