Journal Of Scientific Innovations In Anesthesiology
Journal title : Journal of Scientific Innovations in Anesthesiology
Publisher : Revo Publication
Page Number : 19-24
Journal volume : 1
Journal issue : 1
28 Views Original Article
Background: Measurement of patient health status, or quality of life, has become an important end-point in clinical studies as it represents in part the patient perception of their outcome of care. The objective of this study was to evaluate the effects of systemic dexmedetomidine on intraoperative hemodynamics, postoperative quality of recovery and analgesia. Materials and Methods: 90 subjects posted for elective lower abdominal surgeries under general anesthesia were randomized to receive infusion of dexmedetomidine (1 mcg/kg over 15 minutes followed by a 0.06 mcg/kg/h infusion until the end surgery) (Group 1) or Normal saline (10 ml over 15 minutes followed by infusion @1ml/kg/hr till end of surgery) (Group 2). Intraoperative hemodynamics, extubation variables, postoperative analgesic requirement and quality of recovery score were evaluated. Results: Intraoperative infusion of dexmedetomidine resulted in maintained hemodynamics, achieving early extubation parameters. Time for first postoperative analgesic requirement was increased while total analgesic requirement was decreased with use of dexmedetomidine. Median QoR-40 score was better with the use of dexmedetomidine compared to control group. Conclusion: Use of Intraoperative infusion of dexmedetomidine was associated with early recovery, decreased postoperative analgesic requirement better Quality of Recovery score signifying greater patient satisfaction. Keywords: Dexmedetomidine, Quality of recovery-40, Postoperative analgesia, hysterectomy, General anesthesia
DOI : https://doi.org/10.65929/JSIA.2026.1.1.003
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