Mediterranean Journal Of Pharmacy And Pharmaceutical Sciences

Prevalence of comorbidity and polypharmacy among hospitalized elderly patients

  • Authors Details :  
  • Mustafa A. Alssageer,  
  • Esraa S. Mohammed,  
  • Soaad A. Abd-alsalm

597 Views Original Article

Aging seldom comes alone and it is considered to be the major factor for many diseases and comorbidities and disabilities. The objectives of the study are to examine demographic characteristics and prevalence of comorbidities and polypharmacy of elderly patients who were admitted at Sebha Medical Center according to the selected period. This study is descriptive and retrospective cross-sectional study conducted in Sebha during 2021. From 195 participants of the study, the highest rate of patients was from the age group of 65 - 74 years which accounted for 86 participants (44%) and followed by those age group of 75 - 84 years which was reported by 65 participants (33%). The majority of elderly patients have hypertension, (n = 116, 59%) and over one-third of the patients (n = 73, 37%) have diabetes mellitus while nearly one-quarter of patients have both diseases at the same time (n = 47, 24%). Nearly, three-quarters of patients have electrolytes imbalance (n = 142, 72%). Nearly, two-thirds of the patients had three to five comorbidity diseases (n = 122, 63%). Whereas, over one-third of the patients had just one or two comorbidities (n = 70, 36%). Almost all the participants have polypharmacy (n = 187, 96%). Just above half of the patients have five - ten medications (n = 100, 51%) compared with 45% of the patients from those who have more than ten medications (n = 87). This study showed that there is a strong relationship between the prevalence of polypharmacy and the number of comorbidities. A Spearman correlation test indicated that rate of comorbidities was related to polypharmacy with a significant correlation (P < 0.01). The present study found high prevalence of comorbidities and polypharmacy among elderly inpatients. Based on this high prevalence, practicing pharmaceutical care could play an effective role to reduce the risk of inappropriate polypharmacy among hospitalized elderly patients through encouraging clinical pharmacist to engage in clinical activities in hospitals.

Article DOI & Crossmark Data

DOI : https://doi.org/10.5281/zenodo.6399521

Article Subject Details


Article Keywords Details



Article File

Full Text PDF





More Article by Mediterranean Journal of Pharmacy and Pharmaceutical Sciences

The perspective of covid-19 vaccines

The current covid-19 is now endemic on everycontinent and becomes the most challenging outbreaks over centuries, thus millions of people have been infected with the novel coronavir...

Mokhtar r. haman: a dedication to his memory

It is with more sorrow and tremendous sadness we remember the death of our colleague the libyan pharmacist, professor mokhtar ramadan haman, at his home in tripoli, libya after lon...

In silico studies of 2-(4-(aminomethyl)phenyl)isoindoline-1,3-dione schiff base derivatives as potential inhibitors against main protease covid-19 enzyme

The 2019 coronavirus (covid-19) pandemic is spreading worldwide, with a spectacular increase in death missing any effective therapeutic treatment up to now. molecular docking is a ...

Phytochemical screening and structure elucidation of isolated compounds from convolvulus dorycnium plant originated from west of libya

Plants are an ancient source of medicine due to the presence of bioactive molecules of various compounds in their different parts. convolvulus dorycnium plant belongs to the family...