Mediterranean Journal Of Pharmacy And Pharmaceutical Sciences

Serum uric acid as an adjunct in the assessment of psychiatric disorders: an overview

• Authors Details :  
• Jagannadha R. Peela,  
• Abdalla M. Jarari,  
• Harshvaradhan Polamarasetty,  
• Vaishnavi Kanisetti,  
• Krishna Srivathsav Tadikonda,  
• Anuradha Argi,  
• Avinash K. Rawal

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Oxidative stress is due to altered levels of prooxidants and anti-oxidants in the body. This can lead to tissue damage especially the central nervous system. Oxidative damage has been implicated in several disorders including some psychiatric disorders such as schizophrenia and major depressive disorder. Uric acid is an anti-oxidant which prevents tissue damage caused by oxidative stress. In this review, the reduced levels of serum uric acid in schizophrenia and depression are discussed. The effect of treatment in these disorders leading to increased serum uric acid levels are also reviewed.

Article DOI & Crossmark Data

DOI : https://doi.org/10.5281/zenodo.6780474

Article Subject Details

• Biochemistry
• Clinical pharmacy

Article Keywords Details

• oxidative stress
• schizophrenia
• uric acid
• Major depressive disorder

Article File

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