The anti-depressant activity of fixed oil of phaseolus vulgaris linn. in mice

Salma Sabir; Sadia Ghousia Baig; Muhammad Mohtasheem Ul Hasan; Afshan Siddiq; Salman Ahmed; Syeda Anum Fatima

Dr. Salman Ahmed

Authors Details :
Salma Sabir ,
Sadia Ghousia Baig,
Muhammad Mohtasheem Ul Hasan ,
Afshan Siddiq ,
Salman Ahmed,
Syeda Anum Fatima

Journal title : Pakistan Journal of Scientific & Industrial Research Series A: Physical Sciences

Publisher : PCSIR-Scientific Information Center

Print ISSN : 2221-6413

Page Number : 1-5

Journal volume : 64

Journal issue : 1

36 Views Original Article

Phaseolus vulgaris Linn commonly known as red kidney bean, is enriched in protein, carbohydrates and dietary fibres. Beans have nutritional and health benefits and possess antimicrobial, antihyperglycemic, antioxidant and anticancer activity due to bio-active chemical constituents. The following study was carried out to evaluate the anti-depressant activity of Phaseolus vulgaris fixed oil (PVFO) using a forced swim test and tail suspension test in mice. In this study, animals were assigned into four groups (n=7). Group I: Control normal saline (2 mL/Kg), Group II: PVFO I (2 mL/Kg), Group III: PVFO II (4 mL/Kg) and Group IV: standard amitriptyline (10 mg/Kg). The significant results indicated the possible anti-depressant role of Phaseolus vulgaris fixed oil.