Prasanna Pradhan

Uv spectrophotometric determination of cefixime in bulk and its dosage form

• Authors Details :  
• Suddhasattya Dey,  
• Prasanna Kumar Pradhan,  
• Um Upadhayay,  
• Shreya Shah,  
• Kuntal Goswami

155 Views Original Article

A novel, simple, accurate, sensitive, reproducible, economical and less time consuming spectroscopic method was developed and validated for determination of cefixime. The solvent used was 0.1 N HCL and the absorbance maxima or the λmax was found to be 283.0 nm and 303nm for zero order and first order derivative respectively. This method obeyes Beer’s Law for the concentration range of 8–16 µg/ml for cefixime. The proposed method was been validated statistically as per the ICH guidelines for linearity, accuracy, precision, specificity, LOD and LOQ. The method developed and validated successfully for the quantitative analysis of cefixime in bulk and dosage form.

Article Subject Details

• Pharmaceutical analysis

Article Keywords Details

• Cefixime

Article File

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