Pharmacy articles list

The present study is designed to determine the types of secondary metabolites in three selected seed powders using a fast, reliable, and non-destructive Near Infra Red spectroscopic analytical technique. NIRS analysis of Macrotyloma uniflorum (Lam.) Verdc., Phaseolus lunatus Linn., and Phaseolus vulgaris Linn., seed flours were used to qualitatively evaluate secondary metabolites. The fine powder of crude drug was directly applied to FOSS XDS near the infrared Rapid Content Analyzer. The adequately filled powdered sample in a disposable glass silicate vial closed with a plastic lid was centrally placed onto the Foss Rapid Content Analyzer sample presentation glass. The scanning of samples at ambient temperature gives NIR spectra within 30 seconds. The major proposed compounds in M. uniflorum were 3,4-dihydroxybenzoic acid, caffeic acid, chlorogenic acid, ferulic acid, gallic acid, kaempferol, linolenic acid, niacin, quercetin, sinapinic acid, syringic acid, and vanillic acid. Whereas coumaric acid, fructose, galactose, L-serine, raffinose, stachyose, sucrose, threonine, and tyrosine were detected in P. lunatus, and the NIR suggested the presence of caffeic acid, ferulic acid, sinapinic acid, phytic acid, leucine, and valine in P. vulgaris. NIRS is an advanced innovative technology extensively used in chemical, food, petrochemical, and pharmaceutical industries for rapid and reliable standardization. The present study revealed an excellent correlation to conclude that flour samples of all three legume seeds could be added to the food system to achieve nutritional and functional benefits.

Dr. Salman Ahmed

Urolithiasis arises from disturbances in the urinary tract's physicochemical balance and hydrodynamic system. Medicinal plants have been known for millennia and are highly esteemed worldwide as a rich source of therapeutic agents for the prevention of various ailments. A comprehensive literature search of antiurolithiatic plants reported worldwide revealed the family Fabaceae with the highest number of cited species. The members, Macrotyloma uniflorum (Lam.) Verdc., Phaseolus lunatus Linn. and Phaseolus vulgaris Linn. have been selected and hidden versatile weapons of their seeds against urolithiasis such as analgesic, antioxidants, astringent, diuretic, emollient, high soluble oxalate contents, insoluble fibers, magnesium, potassium, phytic acid, pyridoxine (vitamin B6), have been discussed on a scientific basis to rationalize the folkloric use.

Dr. Salman Ahmed

The presented review was an attempt to share the contribution of Greco Arabic Muslim scientists in the field of medicine. In this regard, al-Andalusi, al-Antaki, al-Baghdadi, al-Jawhari, al-Kindi, al-Nafis, alRazi, al-Tabari, al-Zahrawi, Ibn Abdallah Ibn Idris al Qurtubi, Ibn al-Jazzar, Ibn al-Baitar, Ibn alHaitham, Ibn El-Quff, Ibn Haiyan, Ibn Sina, Ibn Wahshiyyah and Ibn Zuhr with their contribution has discussed.

Dr. Salman Ahmed

: About 12% of the world population is affected by different forms of urolithiasis, the recurrence rate of which is 47-60% in females and 70-80% in males. According to WHO, 75% of people rely on traditional medicines to prevent and cure different ailments. Similarly, the majority of the world population uses several plants to treat problems related to the urinary tract system, of which urolithiasis is the primary cause. The review aims to collect data on the plants used in different parts of the world and cultures against urolithiasis, including their parts, mode of preparation, dosage, and administration. A literature review was conducted for traditionally used antiurolithiatic plants. The articles mentioning plant, parts, mode of preparation, dose and route of administration were selected. This information was extracted to compose Mono and Polyherbal antiurolithiatic formulations used in Appalachia (a region in the Eastern United States), Canada, India, Iran, Israel, Italy, Jordan, Latin America, Pakistan, Turkey and Yemen. The review provides essential data about plants used as antiurolithiatic in different parts of the world. The information is not only useful for ordinary people but also for the scientific community to carry out further phytochemical, pharmacological and toxicological studies for discovering new, effective, safer molecules against urolithiasis.

Dr. Salman Ahmed

The present review shares an updated data on the botany, distribution, traditional medicinal uses, phytochemistry and pharmacology of Phaseolus lunatus L. All provided information was obtained through Google Scholar, Pubmed, Sci Finder, Scirus, Web of Science and library search.

Dr. Salman Ahmed

The present review shares updated data on the botany, distribution, medicinal uses, phytochemistry and pharmacology of Phaseolus vulgaris L. All provided information was obtained through Google scholar, Pubmed, SciFinder, Scirus, Web of Science and a library search.

Dr. Salman Ahmed

Prescription drug misuse has emerged as a significant problem over the past decade, particularly topical corticosteroids for skin lightening. This study aimed to assess the misuse of topical corticosteroids among the female population in southern Libya; to determine prevalence, awareness, attitude, and practice regarding this drug misuse. A descriptive, cross-sectional questionnaire was distributed on January 2022 to females aged between 16-45 years old in southern Libya. Out of 200 distributed questionnaires, 155 were returned with a response rate of 77.5%. The majority of the participants were aged 16-25 years (n=138, 89.0%) and over two-thirds of participants, said they obtained lightening products containing cortisone from pharmacies (n=107, 69.0%) while 36 participants indicated they obtained these products from cosmetic shops (23.2%). More than three-quarters of the participants said they were aware that they should read product ingredients (n=120, 77.4%). Just over one-quarter of respondents indicated they used the product on their face almost daily (n=41, 26.5%) while 28 participants denied using it (18.1%). The most common source of information about topical corticosteroids among participants was the Internet (n=51, 32.9%), followed by dermatologists (n=41, 26.5%), and pharmacists (n=31, 20.0%). Almost half of respondents were aware that topical corticosteroids can cause harmful effects (n=75, 48.4%). The most common indications reported for using topical corticosteroids were whitening (23.3%), and acne treatment (54.2%). Over two-thirds of participants, declared they would not use topical lightening products if they contained corticosteroids (n=107, 69.0%). In a similar attitude, nearly a third of participants stated that they would never use corticosteroid medications again if they knew about the negative effects of whitening (n=51, 32.9%). The majority of females, (87.7%), concur that only pharmacies should be able to sell and prescribe topical corticosteroid medications. The study's findings indicate that topical corticosteroids are frequently misused and that to lessen contraindications, especially for prolonged use, it is imperative to provide basic care to females who continue using topical corticosteroids in public or unlicensed marketing settings.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences

NIRS is an advanced, fast, reliable, and non-destructive technique that is extensively used in the chemical, food, petrochemical, and pharmaceutical industries for rapid and reliable standardization. NIRS of Cicer arietinum L. Desi and Kabuli variety seed flours were performed to evaluate secondary metabolites qualitatively. The principal suggested compounds in Cicer arietinum Desi and Kabuli variety were found as adenine, biochanin-A, biochanin-B, biochanin A 7-O- β -D-glucoside, calycosin, cerebroside, choline, ciceritol, citric acid, daidzein, fructose, garbanzol, genistein, glucose, inositol, isoliquiritigen, liquiritigenin, methyl tetracosanoate, ononin, pyrimidine, saccharose, sissotrin, stigmasterol, trifolirhizin. β- amyrin and β-sitosterol. These compounds' presence justifies using Cicer arietinum as a nutritional food and tonic.

Dr. Salman Ahmed

Emesis is defined as a forceful expulsion of stomach contents via the mouth. The adverse effects of available anti-emetic drugs potentiate us to evaluate natural products to explore effective natural anti-emetics with fewer side effects. The fruits of Illicium verum Hook. f. were selected for anti-emetic activity based on their folkloric use against gastrointestinal complaints. Crude methanolic extract and its aqueous, dichloromethane, ethylacetate and hexane fractions were evaluated using the copper sulphate-induced chick emesis model. Emesis was induced by the oral administration of copper sulfate 10 ml/kg body weight and metoclopramide (150 mg/kg p.o.) as a standard anti-emetic drug. The anti-emetic effect was observed by calculating the mean decrease in the number of retches compared to that of the control. Methanolic extract and its fractions were tested at 25, 50 and 75 mg/kg oral doses. Among all tested fractions, ethyl acetate showed the highest (94.46%), and hexane showed the lowest (56.30%) anti-emetic activity at 50 mg/kg. Further, isolation and purification from the same fractions are in process to discover effective natural anti-emetic compound(s) with less unwanted effects.

Dr. Salman Ahmed

This review shares historical glimpses of the art and science of urinary crystal growth in the gel. This successful journey of long and detailed research consists of theoretical and experimental knowledge. The survey consists of historical aspects of crystal growth, the development of urinary crystal growth in the gel as an in vitro urolithiasis model and the application of this model to evaluate prophylactic management against kidney stones.

Dr. Salman Ahmed

Whewellite crystals are most commonly found in the kidneys, ureter and urinary bladder, causing urolithiasis. The present in vitro study aimed to observe the possible growth patterns and morphology of whewellite crystals. The study was carried out in U-shaped test tubes. Bow shape, donuts and their aggregates, dumbbell, platy, prismatic, rosette, styloid, X-shape and tetragonal bipyramidal crystals were observed. Energy Dispersive X-ray, Fourier Transform Infra-Red spectroscopies and Scanning Electron Microscopy were used to characterize the crystals. This study will be helpful in determining the promotion, modulation, and inhibition of the crystals, as well as evaluating risk factors and prophylactic management of urinary stones.

Dr. Salman Ahmed

Marine algae have been known and utilized since the ancient era. It is the source of chemical compounds mainly useful as a food for their richness in protein, fatty acids, minerals and vitamins. Physiologically active compounds also have a great potential to play an important role in cosmetics, medicine and pharmaceutical aid. In this review, the information provided will play an essential role in future medicinal and cosmeceutical production.

Dr. Salman Ahmed

Medicinal plants are the gift of nature and play an important role as a part of our diet to maintain health. They also serve as a versatile weapon to combat several diseases. Every civilization has its own experience and knowledge of the therapeutic uses of plants. The belief and observations regarding traditionally used medicinal plants increase people's interest in using them against urolithiasis. Urolithiasis is a common problem that has been afflicted for centuries and has a high recurrence. Of the world's population, about 12% suffer from urolithiasis. All over the world, in different countries and cultures, people use plants to prevent and cure kidney stones according to their ethnopharmacological information. These formulations are very effective. That's why they have been used for hundreds of years. This review covers the eighty (80) medicinal plants of the most cited family Asteraceae against urolithiasis and their historical antiurolithiatc background shared in well-known books of Dioscorides, Pliny the Elder, Al Razi and Ibn Sina. This information was extracted to compose antiurolithiatic plants with their parts and formulations used in 21 countries such as Algeria, America, Australia, China, India, Iran, Italy, Jordan, Jordan, Kyrgyzstan, Lebanon, Libya, Mexico, Morocco, Pakistan, Palestine, Philippine, Spain, Tunisia, Turkey and Uzbekistan. Scientifically proven pharmacological activities of the same part of the plant have direct (litholytic) and direct pharmacological effects like analgesic, anti-inflammatory, antioxidant, astringent, demulcent, diuretic, litholytic, lithotriptic, antiurolithiatic, antispasmodic, ACE inhibition and Phospholipase A2 inhibition also shared as a plausible mechanism of action. The route of administration is oral in all cases. Hopefully, this book will be useful for the general public and attract the scientific world for antiurolithiatic drug discovery. This valuable ethnopharmacological information will provide opportunities for the future research and development of new natural antiurolithiatic compounds.

Dr. Salman Ahmed

Urolithiasis is a common problem that has been afflicted for centuries and has a high recurrence. This review covers the sixty-four (64) antiurolithiatic plants of the family Fabaceae used in 18 different countries and their historical antiurolithiatc background. Hopefully, this review will be helpful for the general public and attract the scientific world for antiurolithiatic drug discovery.

Dr. Salman Ahmed

Urolithiasis has been a common problem for centuries and has a high recurrence. This review covers the forty-two (42) antiurolithiatic plants of the family Apiaceae used in 18 different countries. Hopefully, this review will not only be helpful for the general public but also attract the scientific world for antiurolithiatic drug discovery.

Dr. Salman Ahmed

Urolithiasis has been a common problem for centuries and has a high recurrence. This review covers the forty-nine (49) antiurolithiatic plants of the family Lamiaceae used in 11 countries. Hopefully, this review will be helpful for the general public and attract the scientific world for antiurolithiatic drug discovery.

Dr. Salman Ahmed

Brushites are the most commonly found phosphate stones in the kidneys, ureters and urinary bladder. The study was conducted to observe the possible growth patterns of brushite crystals in the gel for 14 days. The crystal formation was observed as a bullet, needle, platy, columnar shaped and their aggregates. Magono and Lee's meteorological classification further explained these shapes. Besides the morphology, the average size, number and weight of crystals were also observed on the 7th and 14th days. Energy Dispersive X-ray, Fourier Transform Infra Red spectroscopy and Scanning Electron Microscopy were used to characterize the crystals. These results can help to determine the promotion, modulation and inhibition of the crystals, which will be helpful in evaluating the risk factors and prophylactic management of brushite-type urinary stones.

Dr. Salman Ahmed

Urolithiasis is a common worldwide problem with high recurrence. This review covers the forty-one (41) antiurolithiatic plants of the Rosaceae family that are used in 14 countries. Hopefully, this review will be helpful for the general public and attract the scientific world for antiurolithiatic drug discovery.

Dr. Salman Ahmed

Urolithiasis is a common worldwide problem with high recurrence. This review covers twenty-three (23) families starting from alphabet S to Z. It includes Solanaceae (12); Zingiberaceae (09); Scrophulariaceae and Urticaceae (08); Verbenaceae (07); Ulmaceae, Valerianaceae and Vitaceae (05); Zygophyllaceae. (04); Sapotaceae, Saxifragaceae and Typhaceae (03); Smilacaceae (02); Salicaceae, Salvadoraceae, Santalaceae, Simaroubaceae, Tamaricaceae, Tiliaceae, Theaceae, Tropaeolaceae, Violaceae and Xanthorrhoeaceae (01) plant used globally in different countries. Hopefully, this review will be helpful for the general public and attract the scientific world for antiurolithiatic drug discovery.

Dr. Salman Ahmed

Urolithiasis is a common worldwide problem with high recurrence. This review covers thirteen (13) antiurolithiatic plants of the family Boraginaceae, twenty (20) from Brassicaceae, twenty-three (23) from Malvaceae and twenty-four (24) from Poaceae used globally in different countries. Hopefully, this review will be helpful for the general public and attract the scientific world for antiurolithiatic drug discovery.

Dr. Salman Ahmed