COVID-19 pandemic has spread all over the world and has caused psychological impacts. Medical students are known to be vulnerable population, experiencing higher levels of anxiety, depression and other psychological disorders compared to non-medical students. The nature of life changes like what happened and still happening during the pandemic have its impact on mental health of the students. The aim of this study was to identify the psychological impacts of COVID-19 on medical students among different universities to develop profiles to characterize students' anticipated levels of psychological impacts during the pandemic. Also, to search for potential risk factors that could make students more likely to experience these impacts. An online survey was filled by medical students (n = 100) at faculties of medicine, dentistry, pharmacy and medical sciences of different universities: University of Benghazi, Libyan International Medical University, Omar Almokhtar University, Cairo University and Alexandria University. The students were taken to the further analysis. Thus, 55% of the participants had psychological impacts due to the pandemic and 17% had severe effect. Some of these impacts were actually positive as a large number (58%) of the participants felt relaxed during the pandemic. Multiple stressors were identified that contributed to the increased levels of stress, anxiety and depression. These included concern about academic performance (80%), concern about self/dear-one’s health (90%), difficulty with concentration (46%), disruption to sleeping patterns (78%), increased social isolation (26%), disruption to eating patterns (48%), changing in the living environment (26%), financial difficulties (34%) increased class workload (20%) depressive thoughts (37%) and suicidal thoughts (07%). In conclusion, the study indicates that COVID-19 pandemic have positive and negative impacts on medical students. Thus, it is suggested that measures need to alleviate students’ stress, which might have harmful effects in different aspects.
Mediterranean journal of pharmacy and pharmaceutical sciences
The scaling of metabolic rates with body mass is one of the best known and most studied characteristics of aquatic animals. We studied here how size is related to oxygen consumption, ammonia excretion and O: N ratio in Freshwater Bivalve Mollusc Lamellidens marginalis species in an attempt to know how size specific changes affect their metabolism. The freshwater bivalve molluscs with specific size i.e. small (77 79 mm in shell length) and large (90 93 mm in shell length) were selected for experimental work from Bhima River at Siddhatek on December and January during winter. The adult bivalve molluscs with small size reported high value in oxygen consumption and O: N ratio but ammonia excretion was low value in small sized bivalves compared to large ones. The results are discussed in the glow of metabolic processes in fresh water bivalve molluscs.
We exist in a conscious experience of life that is transitive and moment-by-moment, yet significant enough non-zero-time latencies exist across the visual, auditory, and somatosensory systems that transduction and processing do not take place instantly. This paper attempts to examine these non-zero-time latencies to resolve the conflict, ultimately suggesting that instead of consciousness accessing an external world, it accesses a high-fidelity bioelectric representation of the external world generated during this pre-conscious time interval. This external representation is the byproduct of Default Space Theory (DST), which indicates that oscillatory movements of the brain and body form a continuous three-dimensional "default space" over time. The default space exists as we exist, separately. Our external inputs from the retina, cochlea, and dermis "clothing" the default internal configuration occur via phase-locked neural oscillations over time, which occur at significant non-zero latencies. For example, the earliest cortical stages for auditory and tactile processing occurs at ~10–20ms, while the olfactory and visual features of stimuli occur at ~50–70ms. This doesn't mean we're perceiving them in time; it's quite the opposite. We're not perceiving in time because the default space is so well-templated all at once that somehow, the brain must erase this time interval and use the integrated multisensory processing to update continuously. Thus, we need to redefine consciousness as this continuously updated internal projection of externalized realities instead of an experience of what's outside.
Lycium schweinfurthii is a shrub belonging to the Solanaceae family which widely grows in North Africa and Mediterranean regions. The plant leaves have traditionally been used for gastrointestinal diseases as peptic ulcer in Libya. This study aimed to investigate the effect of Lycium schweinfurthii extract on the central nervous system in mice including anticonvulsant, antidepressant and muscle relaxant activities. The methanolic extract was prepared by fractionation technique. Albino male mice weighing 22 ± 2.0 gm were used and equally divided into equal number and weight for each experiment (n = 6). The best effective pharmacologically dose of 400 mg/kg, i.p. of the methanolic extract was selected to explore the anticonvulsant activity for picrotoxin-induced convulsion in mice (5.0 mg/kg), antidepressant activity of forced swimming test of depression and muscle relaxant action by motor coordination test of hanging wire. Fluoxetine (10.0 mg/kg), imipramine (15.0 mg/kg) and diazepam (5.0 mg/kg) were used as reference compounds. Lycium schweinfurthii extract exhibited a significant prolonged delay in the onset time of induced convulsion and significant decrease in the frequency of convulsion as well as a significant decrease in the duration time of attacks. Pretreatment with flumazenil (2.0 mg/kg) was found to increase the frequency and duration of convulsions without profound change in the onset time produced by Lycium schweinfurthii. For antidepressant activity, the plant leave extract significantly decreased immobility time duration without a muscle relaxant effect. The results suggest that the methanolic extract of Lycium schweinfurthii leave has anticonvulsant and antidepressant-like activities without any muscle relaxant effect in mice. Thus, Lycium schweinfurthii may have a neuropharmacological potential use in human.
Mediterranean journal of pharmacy and pharmaceutical sciences
Overall, disability refers to a physical or mental state that impairs an individual's ability to function in daily life. It suffices to say that disability is a medical-social issue that affects both the family and the nation. In a country like India, where girl children are frequently stigmatized as a burden on society, the condition of girl children with special needs is frequently subject to carelessness, lack of compassion, and illiteracy. Though the situation has improved slightly since the introduction of inclusive education, the situation is critical for tribal girl students with special needs. In a fragile socioeconomic environment, tribal girls are already vulnerable to high dropout rates, early marriage, and an ignorant attitude from family members, but the situation is pitiful for tribal girls with special needs. The tribal girl students with special needs suffer quadruple discrimination of being female, being disabled, being ST, and being socio-economically backward. Here, intervention through artificial intelligence (AI) and AI-assisted devices can be critical in overcoming the barriers encountered by tribal girl students with special needs in the process of inclusion and development
This study analyzed the performance of hybrid ORC -Stirling systems in terms of thermal-mechanical energy conversion in relation to small-scale power generation by industries in Delta state, Nigeria. The two main parameters examined included the thermal collection efficiency of evacuated tube collectors and the influence of the environmental parameters on the stability of torque and the power output of the shaft. The data collection was performed on solar irradiance, ambient temperature, wind speed and PCM thermal cycling at 8-hour intervals in 90 days, and analyzed by means of MATLAB-simulated multidimensional plots. Findings showed that evacuated tube collection produced efficiency of ≥65% thermal collection efficiency, providing sufficient heat input for ORC–Stirling systems to maintain torque deviations within ±5% and conversion efficiency ≥40%. Mean solar irradiance of 775W/m²and PCM cycling between 250–310°C supported continuous 8-hour daily operation of industrial machinery. The results showed that hybrid ORC-Stirling systems are reliable to drive small-scale industrial processes even when environmental conditions vary. It was therefore advised that the small-scale operators should invest in ORC-Stirling systems, the Manufacturer Association of Nigeria (Delta State Chapter) should create awareness and demonstrations of this hybrid ORC-Stirling system and tertiary institutions in Delta state should engage the faculties of Mechanical Engineering to conduct training and pilot projects to facilitate adoption and proper maintenance of this ORC-Stirling system. Such measures will further improve operational stability, cut down-time and sustainability and decentralized industrial power
Green computing is focusing on reducing the energy consumption, resource usage, carbon dioxide emission. It was found that Last year, Google used about 12.4 terawatt-hours of electricity. Energy consumption in data centers is reduced by decreasing the resource utilization that is by switching off or shifting the computing nodes to sleep mode. But when the servers are being used the energy consumption is minimized by using energy efficient scheduling and optimization techniques.In WNS the sensor nodes are deployed in remote areas, these sensors are powered by battery that decreases the lifetime, therefore by using energy efficient techniques can increase the uptime of the battery-operated devices in WNS. This work studied various energy efficient techniques that minimize energy consumption usage in Data Centers (DC) and the algorithms that increase the uptime of the battery-operated device in (WNS) Wireless Network Sensors.
Obsessive-compulsive disorder (OCD) is a mental disorder that causes repeated unwanted thoughts or sensations, or do something over and over again. It is affecting all ages in the world. It is unusual for symptoms to begin after the age of 35 and half of people develop problems before 20. This making university students a target of OCD. This study investigates the prevalence of symptoms of OCD and identifies possible risk factors among pharmacy students of University of Tripoli, Libya. 80 pharmacy students registered in the final academic year 2019/2020 were enrolled in this study. All the participants were females ranging of 22 to 24 years old of a same environmental background. This study is based on a validated questionnaire for screening of OCD as mentioned by the American Psychiatric Association without modification. A total of 63 students have returned the questionnaire (response rate, 78.8%). The study shows that OCD symptom is relatively common among pharmacy students. The most common symptoms are losing something of importance (71%) and checking things over and over or repeat actions many times to be sure they are done properly (63%). Among OCD symptoms, the most common associated trigger factors were stress and phobia which representing 62% of the participated students. This study indicates that pharmacy students are at risk of being susceptible to getting OCD. OCD affects academic performance and quality of student life, therefore, a psychological and health services for university students should be implanted.
Mediterranean journal of pharmacy and pharmaceutical sciences
Pheochromocytoma is a catecholamine-producing neuroendocrine tumor leading to hypertensive crises in untreated patients. Presentation in pregnancy can mimic gestational hypertension or pre-eclampsia. Physicians need to keep a high index of suspicion to have timely diagnosis and management of pheochromocytoma during pregnancy. We report a 27-year-old female who was diagnosed with pheochromocytoma at 18 weeks of gestation and she underwent laparoscopic adrenalectomy at 22 weeks of gestation with a good pregnancy outcome and with no recurrence over 8 years of follow-up.
Conservation of Biodiversity is an activity must carry out by all individuals in the world to share the benefits derived from biodiversity. It is a critical task to conduct the biodiversity census and conservation (Biodiversity C & C or Biodiversity C2). Throughout the world several Governament and Non-Governamental organizations work together as a unit to maintain our biodiversity in safe mode. India is a mega diverse country with rich biodiversity. The development of modern science and technologies have increased the value of biodiversity and associated traditional knowledge. To save valuable biodiversity and traditional knowledge of our country, National biodiversity board and State biodiversity board constantly involved in this approach and biodiversity law's support to conserve the living diversity.
Frequent power outages arising from poor state of electricity infrastructure is hindering Nigeria’s socio-economic growth. Port Harcourt is one of the foremost cities in Nigeria where business and social activities are becoming rapidly more dependent on electricity. Any power outage, even of the shortest duration, in Port Harcourt City has severe socio-economic impacts and there is no likelihood that the phenomenon would abate even in the nearest future. This research investigated the causes of incessant power outages in Port Harcourt City and suggested remedial measures to reverse the trend. The researcher relied on datacollected from primary sources through personal observations, interviews and discussions with residents of the City and from secondary sources such as the National Bureau of Statistics (NBS), the Manufacturers Association of Nigeria (MAN) and current scholarly literature relating to this research, over a period of twelve months. The study used a descriptive and the non-parametric simple percentages technique in analysing the data so collected and in drawing conclusions. It was found that inadequate power generating capacity, shortage of gas, weak and dilapidated electrical transmission and distribution network, inadequate power infrastructure facilities, etc. are the chief causes of incessant power outages in the Port Harcourt metropolis. The paper recommends, among others, immediate upgrade of existing power infrastructure facilities, review of government policy on domestic gas supply and stiff statutory legislation on vandalism as measures to stabilise electricity supply in the Port Harcourt city.
Power and dominance exist everywhere and occur at the macro and micro levels. Being powerful and domineering are factors that serve as emblems for the people in the realm of politics. Power relations are overtly exercised in such discourse. But what is interesting is how power and dominance exist between or among those people who are branded as “powerful;” thus, using the Face Theory of Brown and Levinson (1978), this discourse analysis paper analyzed the power relations that transpired in a senate hearing and its relationship with the Face Threatening Acts (FTAs) used by the people involved in the discourse. A Philippine Senate hearing excerpt served as the primary corpus for analysis. Results showed that the people in the discourse were all powerful, creating tension when they projected their dominance on one another. Each member threatened and challenged their positive and negative faces. The power play evolved into a "pass-theball" effect, and no one has absolute power because it weakens once the person wielding its face is threatened. Hence, to disempower the empowered, a person must learn how to play and use FTAs such as insulting, disagreeing, disapproving, provoking, commanding, and demanding against the powerful to strike a social balance.
This research work aimed to evaluate the effects of thermal processing treatments on the nutrient anti-nutrient composition of Afzelia africana (Akparata) flour. The seeds were sorted, cleaned and processed into boiled, roasted and autoclaved lima bean flours. The flours obtained were analysed for proximate, vitamin and anti-nutrient contents using standard methods. The proximate composition of the samples revealed that the flours had a range of moisture, 8.23-12.40%, crude protein, 15.98-25.95%, fat, 21.00-28.21%, ash, 1.34-2.89%, crude fibre, 2.00-3.45%, carbohydrate, 38.68-49.33%, and energy 424.13 – 482.37kJ/100g, respectively. The vitamin contents of the flours showed that the samples contained 0.02±0.00 - 0.08±0.00mg/100g riboflavin, 0.78 - 1.98 mg/100g niacin, 0.40 - 0.89 mg/100g thiamine, 120.40-234.70mg/100g vitamin A, 72.11-134.19mg/100g ascorbic acid, 09.67-17.65mg/100g vitamin E, 310.60-430.60mg/100g B6, 3.47-5.87mg/100g B12, respectively. The result of the anti-nutrient composition of the flours also showed that the phytate, tannin, oxalate, cyanogenic glycosides, protease inhibitors, haemagglutinins inhibitors, levels of the samples were significantly (p<0.05) reduced by roasting and boiling treatments compared to the sample processed by autoclaving. In addition, the saponin content of the flours was relatively higher in boiled sample than in roasted and autoclaved flours. However, the nutrient and anti-nutrient contents of the flours observed that the flours have the potentials to be used as nutritional supplements in the preparation of a variety of food products than the raw sample.
In the running of the Internet world, Ecommerce industry has its own benchmark in terms of its rapid growth and has made itself an established sector that is indispensable for every industry to trade and do transactions online. As the world is rushing in a rapid manner, India is slogging in the improvisation of the online market, leading to the lack of customized needs of the customers. Bigger companies are trying to put in a different strategic approach taking that into consideration an approach of blended emining along with ecommerce has been devised. It would be a design of the semanticand neuralbased page ranking algorithm [2]. This tool upon launching would be a welldefined approach for ecommerce website ranking [1]. It would also facilitate the customers to find the relevant websites on the top of the page during their search for any particular product orbusiness. It would be further customized with all the relevant comparison of the other websites in terms of the product quality and price.
Many people are distracted from the normal lifestyle, because of the hearing loss they have. Most of them do not use the hearing aids due to various discomforts in wearing them. The main and the foremost problem available in it is; the device introduces unpleasant whistling sounds, caused by the changing environmental noise, which is faced by the user daily. This paper describes the development of an algorithm, which focuses on the adaptive feedback cancellation, that improves the listening effort of the user. The genetic algorithm is one of the computational techniques, that is used in enhancing the above features. The performance can also be compared with other comprehensive analysis methods, to evaluate its standards.
Background: Water distribution systems within healthcare facilities are complex ecosystems that can harbor opportunistic pathogens, posing a significant risk to patient safety. Ensuring the microbiological quality of water requires rigorous monitoring and a deep understanding of the entire system, from source to point-of-use. This study undertakes a comprehensive statistical analysis of microbiological data from a healthcare facility’s water treatment and distribution network to identify contamination hotspots, evaluate the efficacy of critical treatment barriers, and map potential contamination pathways. Methods: This retrospective case study analyzed heterotrophic plate count (HPC) data collected from 29 distinct sampling points throughout a healthcare facility’s water system. The points represented various stages, including municipal source water, intermediate treatment steps (softening, ultrafiltration, reverse osmosis), storage tanks, and multiple points-of-use. Non-parametric statistical methods were employed due to the non-normal distribution of microbial data. A Kruskal-Wallis test with Dunn's post-hoc analysis was used to compare microbial loads across all sampling points. A focused Mann-Whitney U test was performed to assess the performance of the ultrafiltration (UF) unit. Results: The analysis revealed significant variability in microbiological quality throughout the system (Kruskal-Wallis, p<0.0001). One point-of-use and a pre-UF exhibited high median microbial counts and extreme variability, indicating chronic contamination and potential biofilm proliferation. Critically, the ultrafiltration unit failed to demonstrate a statistically significant reduction in microbial load between the pre-filter. Conclusion: The data reveals variability in microbiological levels across the water system, suggesting that the ultrafiltration barrier's performance is a significant factor influencing downstream water quality. The data points to systemic issues, likely involving widespread biofilm, that compromise water quality at the points-of-use.
The space-time dynamics of chlorophyll a concentration and seawater excess viscosity has been investigated in the hydrographically contrasting inshore and offshore water masses of the eastern English Channel. This was done during the phytoplankton spring bloom dominated by Phaeocystis globosa before and after the very large-scale formation of foam induced by an increase in wind-driven turbulence and the related wave breakings. The results suggest that the dynamics of chlorophyll a concentration and seawater excess viscosity are differentially controlled by the formation of foam through the intensity of the spring bloom and wind-generated turbulence.
The mechanical properties of different polymer matrix composites are discussed in this research study. These composites are multiphase materials in which reinforcing elements and a polymer matrix are suitably combined. The mechanical properties of 18 PMCs, including nylon 66 reinforced with 5, 15, and 25% wt% silicon carbide (SiC) and nylon 66 reinforced with 5, 15, and 25% wt% boron carbide (B4C), were evaluated using an injection moulding technique at three different injection pressures in this study. The optimization of process parameters like reinforcement material, reinforcement quantity, and injection pressure to maximize the tensile and impact strength of nylon 66 composites are the main focus of this study. It is observed that the specimens 25% SiC with an injection pressure of 90 MPa has optimised tensile strength, while the specimen 5% B4C with an injection pressure of 90 MPa has optimised impact strength.
Vigna unguiculata (L.) Walp. (Papilionaceae) is a medicinally important plant and is used for the treatment of different diseases. Alkaloids, phenols, flavonoids, and phytic acid have been reported in this plant. Antioxidant, antidiabetic and hypocholesterolemic activities are reported by Vigna unguiculata. The present review attempts to compile all the previous data based on its medicinal uses, phytochemistry and pharmacology reported in the earlier articles.
Medicinal plants are the gift of nature and play an important role as a part of our diet to maintain health. They also serve as a versatile weapon to combat several diseases. Every civilization has its own experience and knowledge of the therapeutic uses of plants. The belief and observations regarding traditionally used medicinal plants increase people's interest in using them against urolithiasis. Urolithiasis is a common problem that has been afflicted for centuries and has a high recurrence. Of the world's population, about 12% suffer from urolithiasis. All over the world, in different countries and cultures, people use plants to prevent and cure kidney stones according to their ethnopharmacological information. These formulations are very effective. That's why they have been used for hundreds of years. This review covers the eighty (80) medicinal plants of the most cited family Asteraceae against urolithiasis and their historical antiurolithiatc background shared in well-known books of Dioscorides, Pliny the Elder, Al Razi and Ibn Sina. This information was extracted to compose antiurolithiatic plants with their parts and formulations used in 21 countries such as Algeria, America, Australia, China, India, Iran, Italy, Jordan, Jordan, Kyrgyzstan, Lebanon, Libya, Mexico, Morocco, Pakistan, Palestine, Philippine, Spain, Tunisia, Turkey and Uzbekistan. Scientifically proven pharmacological activities of the same part of the plant have direct (litholytic) and direct pharmacological effects like analgesic, anti-inflammatory, antioxidant, astringent, demulcent, diuretic, litholytic, lithotriptic, antiurolithiatic, antispasmodic, ACE inhibition and Phospholipase A2 inhibition also shared as a plausible mechanism of action. The route of administration is oral in all cases. Hopefully, this book will be useful for the general public and attract the scientific world for antiurolithiatic drug discovery. This valuable ethnopharmacological information will provide opportunities for the future research and development of new natural antiurolithiatic compounds.