Elevated co2 and temperature resetting the expression of resistance, pest incidence, geographical distribution and physiology in insect-pests of grain legumes

The most important factor that affects the crop production in terms of nutritional content of foliar plants is the global climate change. Herbivore’s growth, development, survival and geographical distribution all are determined by elevated CO2 and temperature. The interactions between herbivores and plants have changed due to increasing level of CO2 and temperature. The effect of high CO2 and temperature on grain legume plant which change in to plant physiology (e.g., nutritional content, foliage biomass) and how it change in herbivory metabolism rate and food consumption rate. Plant injury is determined by two factors viz. resistance and tolerance and both are influenced by greater CO2 and temperature. Legumes are an important source of food and feed in the form of proteins and also improve the soil environment. The repercussions of the abiotic factors mentioned above needs discussion among the scientific community. We may able to limit the negative repercussions of stated factors in future breeding projects by harnessing the practical favourable impacts and by including such influences of elevated CO2 and temperature on pulses productivity. The extensive research is necessary to overcome the negative effects of high CO2 and temperature on insect-plant interaction

DR. BABU LAL JAT Dr. babu lal jat

Effect of educational intervention on osteoporosis among tribal premenopausal women

Background:- Tribals are weaker section which holds in outstanding number of tribal population in our country. They are not having proper knowledge on osteoporosis. Osteoporosis is a significant problem in aging population especially in females, it impacts structural and social burden on health care services in tribals. Objective:- Aim of this study is to determine the knowledge regarding osteoporosis among tribal premenopausal women in tribal area of Guntur Dist. Andhra Pradesh Methods:- This study is descriptive quantitative study conducted among 177 Sugali women & 23 Chenchu women of tribal area in Guntur Dist. Andhra Pradesh from 2015 November to December 2015. A self-administered questionnaire was used to assess the knowledge on osteoporosis by conducting Pre-Tests on this group of people. After Educational Intervention was given with the help of self-instructional module and also conducted a Post Test on these same Group of people Results:- The mean age was 40 to 50 years. Majority of the participants are 177 (100%) Sugali women and 23 Chenchu women in these 177 in which n.150 (84%) women are having poor knowledge and remaining 27 (16%) women have average knowledge. In Chenchu women 20 (86%) women were having poor knowledge and remaining 3 (14%) women have average knowledge on all five aspects of questions regarding Osteoporosis, Menopause, Diet, Exercises and Preventive Methods. After Educational Intervention was given their knowledge was improved by a fraction on Osteoporosis. In the Post-Test 101 (57%) women gained average knowledge but remaining 76 (43%) women remained with poor knowledge among Sugali Women. Out of 23 (100%) women of Chenchu tribe 7 (30%) women got average knowledge and the remaining 16 (70%) women remained with poor Knowledge on Osteoporosis Conclusion:- Although majority of participants had low level of knowledge on Osteoporosis in all aspects regarding Menopause, Diet, Exercises and Preventive methods of Osteoporosis. They perceived a little knowledge on Osteoporosis in all aspects towards preventing Osteoporosis. Comparitively Sugali women are having better knowledge than Chenchu women in all aspects of Osteoporosis. Key words:- Osteoporosis, Knowledge, Effect, Pre-Menopausal, Tribal Women.

Mangeswari K Mangeswari k

Phytochemical evaluation and pharmacological screening of antiparkinson’s activity of allium sativum in swiss/albino mice

Abstract: Objective: To evaluate the Antiparkinson activity of Allium sativum in Haloperidol induced Parkinson‟s disease in mice. Method: Parkinson‟s disease was induced by administering haloperidol (2.0 mg/kg i.p.) Daily for a week. The mice were divided into 5 group (n=6). Group II received haloperidol (2mg/kg body weight).Group III received combination of levodopa and carbidopa (100mg+ 10mg/kg by i.p along with haloperidol) and Group IV and V received Allium sativum extract (200 and 400mg/kg by p.o), respectively for 7 days along with haloperidol. To evaluate the antiparkinson effect of Allium sativum, catalepsy bar test, rotarod test, hang test and horizontal bar test were used. One way ANOVA was used to test statistical significance followed by Bonferroni multiple comparison tests .Results: Allium sativum extract (200 and 400mg/kg by p.o) was found to decrease the duration of catalepsy significantly (P<0.001) in catalepsy bar test as compared to haloperidol group, and significantly increases (P<0.001) fall off time in, rotarod test, hang test and horizontal bar test respectively as compared to haloperidol group. Conclusion: The result of the present study conclusively shows the Antiparkinson‟s activity of Allium sativum in haloperidol induced Parkinson‟s disease in mice.

Zeenath Banu Zeenath banu

Analysis of prop1 gene in a cohort of tunisian patients with congenital combined pituitary hormone deficiency

Background: Non-syndromic combined pituitary hormone deficiency (CPHD) occurs due to defects in transcription factors that govern early pituitary development and the specification of hormone-producing cells. The most common mutations are in the Prophet of Pit-1 (ProP1) gene. This work aims to (1) report findings of genetic analyses of Tunisian patients with non-syndromic CPHD and (2) describe their phenotype patterns and their evolution through life. Methods: Fifteen patients from twelve unrelated families with variable clinical phenotypes were included after excluding autoimmune and acquired forms of non-syndromic CPHD. Detailed pedigree charts and auxological, hormonal, radiological, and therapeutic details were recorded. Sanger sequencing was performed, and sequences were analyzed with a specific focus on coding and splice site regions of the ProP1 gene. Retained variants were classified using several in silico pathogenicity prediction tools and the VarSome platform. Results: We identified the common p.Arg73Cys mutation in seven patients from four unrelated pedigrees. We found a novel homozygous mutation (c.340C>T) in one sporadic case. This mutation generates a truncated ProP1 protein, predicted to be non-functional, lacking the last 112 codons (p.(Gln114Ter)). We confirmed by polymerase chain reaction (PCR) the absence of large exon deletions or insertions in the remaining sporadic patients (7/8). Conclusions: We report two mutations {one newly identified [p.(Gln114Ter)] and one previously reported (p.Arg73Cys)} in five unrelated Tunisian families with non-syndromic CPHD. This work is of clinical importance as it reports the high frequency of the p.Arg73Cys mutation in Tunisian CPHD families. Our study also illuminated the involvement of novel gene(s) in the emergence of non-syndromic CPHD.

Mariam moalla Mariam moalla

A study of foreign direct investment in indian electronics industry

The present study focused on analysing the FDI inflow in Electronics industry form year 2007 to 2018 in country and role of FDI in development of the electronic industry in India. As well identify the current status of Electronics industry in world and the share of India in the same. The present research work also attempted to take overview of various policies introduced by Government of India to promote the FDI in Electronics industry. The FDI inflows statistics reveals that the separate category of Electronics sector is created in year 2007 by DIPP for recording FDI inflow. And sector specific data published in DIPP factsheet revels that this industry has attracted 0.55 % of total cumulative FDI inflow in country till December 2018 which is very negligible share of overall FDI in country. The overview of policies revels that NPE–2012 to New NPE-2018 had attempted to provide multiple incentives for Foreign Investors to establish their electronic manufacturing facilities in country but very negligible response has been seen in response of the same. Further results of study reveals that due to various FTA’s & being signatory of WTO’s ITA-1 in year 1996 leads toward reducing competitiveness of electronic manufacturing in India and country become net importer of approximately 50% of overall domestic need of electronics products.

ANSHUMAN VIJAY MAGAR Anshuman vijay magar

Virtual reality based therapy and parkinson's disease

Parkinson’s disease (PD) is one of the most common neurodegenerative disorders worldwide. It is mainly associated with a loss of dopaminergic neurons in the substantia nigra pars compacta

Nagarjuna narayanasetti

Simulations of solving a single-player memory card game with several implementations of a human-like thinking computer algorithm

The memory card game is a game that probably everyone played in childhood. The game consists of n pairs of playing cards, whereas each card of a pair is identical. At the beginning of the game, the deck of cards is shuffled and laid face down. In every move of the game, the player flips over two cards. If the cards match, the pair of cards is removed from the game; otherwise, the cards are flipped back over. The game ends when all pairs of cards have been found. The game could be played by one, two, or more players. First, this paper shows an optimal algorithm for solving a single-player memory card game. In the algorithm, we defined four steps where the user needed to remember the earlier shown pairs of cards, which cards were already shown, and the locations of the revealed cards. We marked the memories related to these steps as M1, M2, M3, and M4. Next, we made some simulations as we changed the M1, M2, M3, and M4 memories from no user memory (where the player does not remember the cards or pairs of cards at all) to a perfect user memory (where the player remembers every earlier shown card or pair of cards). With every memory setting, we simulated 1000 gameplays. We recorded how many cards or pairs of cards the player would need to remember and how many moves were required to finish the game. Finally, we evaluated the recorded data, illustrated the results on graphs, and drew some conclusions.

Ladislav Végh Ladislav végh

Evaluation of some metformin hydrochloride brands available in the libyan market

Various quality control tests are employed for solid dosage forms such as uniformity, dissolution and drug contents in order to assess their pharmaceutical equivalence. The objective of the current study was to assess and contrast five distinct metformin hydrochloride brands that are offered for sale in the Libyan market. The physicochemical equivalence of the five brands of metformin hydrochloride tablets (500 mg) were determined through the evaluation of official and non-official standards according to the USP including uniformity of weight, friability, hardness, dissolution rate and drug content. All the examined brands available in the Libyan market passed the official weight variation, friability, dissolution and disintegration tests and were equivalent. The friability test was found within the specified limit. All the formulations were disintegrated within 09 - 15 min. The tested brands were non-equivalent to the innovator Glucophage® according to their dissolution evaluation. The percentage content of the active ingredient of five brands of metformin tablets showed values within the monograph specifications (95% - 105%). In conclusion, all the five brands available in the Libyan market which were evaluated in this study cannot be substituted with the innovator product in clinical practice.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

Focus groups

A focus group is an investigative tool for social research based on a structured and focused discussion with a small group of people, run by a facilitator (moderator) to generate qualitative data through a set of open-ended questions. The focus group technique is a qualitative research methodology popularly used in social research in a wide range of sectors. A researcher uses a set of open-ended questions on a specific topic to generate qualitative data. The focus group is an efficient way of gathering data about particular opinions or attitudes by covering a large number of people in the same group. This entry explores the methodology and processes of focus groups as well as the analysis of data from focus group research.

Mukhles m. al-ababneh

Ethnopharmacology - the science behind herbal medicine discovery from ancient wisdom

Drug discovery started when a man suffered from abdominal pain and accidentally healed by chewing the leaves of the plant. The story of Ethnopharmacology begins with the doctrine of signatures, the shape signatures of herbs to heal resembled parts of the body. Later, shape signatures were modified into colour and taste signatures for healing. The information exchange and understanding about people's use of natural resources to discover therapeutic and toxicological potential is now shaped into a branch of science, "Ethnopharmacology". Simply Ethnopharmacology, by using modern science, enables traditional knowledge to convert into medicine and acts as a powerful and creative drug discovery engine.

Dr. Salman Ahmed Dr. salman ahmed

Project risk and procurement management

It is virtually impossible to mention the phrase ‘project management’ without introducing the concept of risk management. As Hillson (2016, p.11) states, “risks [are] particularly relevant to projects” suggesting that effective management of risk is an integral ingredient for project success. The close link that exists between projects and risks may be deduced by the definition of the word ‘project’. In simple terms, projects refer to unique endeavours undertaken with the aim of achieving desired outcomes. These endeavours typically specific start and completion dates, and involve resource, time and cost constraints. These characteristics imply that projects are intended to deliver identifiable benefits to the organisation; these benefits, however, are not enjoyed immediately even if the project is completed. On the contrary, projects commonly create capabilities that call for operation or utilisation for the actual gains to be generated (Hillson, 2016 p.11). The interpretation of this is that projects have a risk element in that they contain a potential reward and possibility of loss. For this reason, project managers must be well-versed with risk management.

Mohamed Sorogy Mohamed sorogy

Mapping the bisexual experience of a keralite woman: glimpses into india

India is not known as a country to be in for a bisexual person. Homosexual acts even within wedlock are a punishable offence in India. Legal battles over provisions in the Indian Penal Code which criminalizes any sexual act “against the order of nature” are rife. Even though Kerala has been hailed as a paradox inside India (mainly due to its human development parameters), the social, cultural and legal environment in the state is hostile to individuals who question hetero-normativity. Non-judgemental and unbiased scientific therapy or counselling are seldom available to sexual minorities. This paper is an attempt to map the experiences of a female who is openly bisexual, and is living in Kerala. An ethnographic interview was conducted where the experiences of the participant are explored, from the relationship dynamics as seen by her, to sexual experiences and difficulties in relationships. A reference is also made to the personal and social support systems that are in place for the Lesbian, Gay, Bisexual, Transgender (LGBT) community in Kerala and their role in initiating discourses regarding the topic. A few pointers for future studies in the topic, especially within the context of Kerala are also put forward.

Dr. Chinchu C Dr. chinchu c

India's modern educational system

The phrase, "The world is ageing, but India has youth on her side," has been a soothing phrase. The average age of the Indian population will be 29 at the conclusion of this decade. As a result of this "demographic dividend," India is expected to account for a quarter of the world's additional increase in working population by 2040. There are 430 million people in our current workforce (ages 15 to 64). India will add 480 million people to its current workforce of 430 million in the next 20 years. Education is the most important tool for converting this demographic dividend into a sustainable economic resource and unlocking human capital's hidden potential. The suggested article attempts to identify gaps and loopholes in the education system utilising the basics of the Capability Approach as a comprehensive mechanism of evaluation and strategies to solve the aforementioned problems, allowing us to take advantage of our country's large demographic dividend.

Dr. Amarjeet Singh Dr. amarjeet singh

Psychological impact of covid-19 pandemic on medical students: an online cross-sectional study

COVID-19 pandemic has spread all over the world and has caused psychological impacts. Medical students are known to be vulnerable population, experiencing higher levels of anxiety, depression and other psychological disorders compared to non-medical students. The nature of life changes like what happened and still happening during the pandemic have its impact on mental health of the students. The aim of this study was to identify the psychological impacts of COVID-19 on medical students among different universities to develop profiles to characterize students' anticipated levels of psychological impacts during the pandemic. Also, to search for potential risk factors that could make students more likely to experience these impacts. An online survey was filled by medical students (n = 100) at faculties of medicine, dentistry, pharmacy and medical sciences of different universities: University of Benghazi, Libyan International Medical University, Omar Almokhtar University, Cairo University and Alexandria University. The students were taken to the further analysis. Thus, 55% of the participants had psychological impacts due to the pandemic and 17% had severe effect. Some of these impacts were actually positive as a large number (58%) of the participants felt relaxed during the pandemic. Multiple stressors were identified that contributed to the increased levels of stress, anxiety and depression. These included concern about academic performance (80%), concern about self/dear-one’s health (90%), difficulty with concentration (46%), disruption to sleeping patterns (78%), increased social isolation (26%), disruption to eating patterns (48%), changing in the living environment (26%), financial difficulties (34%) increased class workload (20%) depressive thoughts (37%) and suicidal thoughts (07%). In conclusion, the study indicates that COVID-19 pandemic have positive and negative impacts on medical students. Thus, it is suggested that measures need to alleviate students’ stress, which might have harmful effects in different aspects.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

A study on corporate social responsibility – a case study with canara bank.

Creating a strong business and building a better world are not conflicting goals – they are both essential ingredients for long-term success. Canara Bank is one of the leading banks in the banking sector which is serving a lot of customers. The initiatives of the Bank under CSR have been the setting up of Trusts and Institutions which have created an impact in serving the people and society at large.Bank has been engaging employees and motivating them employees for participate in CSR activities. Bank has established a Community Development Section’ under FI Wing whose activities include organizing blood donation camps, health check up camps, career guidance and many more. The objective of this paper is to resolve the activities initiated by Canara Bank and the funds allotted in various areas.

Vidya Bhat Vidya bhat

Numerical simulation of electroosmotic flow in a rectangular microchannel with use of magnetic and electric fields

Pumping fluid is one of the crucial parts of any microfluidic system. Using electric and magnetic fields as a substitute for moving parts can have many advantages. In this study hydrodynamic and heat transfer characteristics of electroosmotic flow under influence of lateral electric and transverse magnetic field, are studied numerically. Results indicate that the dimensionless parameters such as Hartmann number, intensity of the lateral electric field, pressure gradient parameter and aspect ratio have an important role in controlling flow. It can be implied that the enhancement of pressure gradient leads to the decrease of critical Hartmann number, and this dependency can be reduced from 44% to 7% for S=0.5 to S=50 in two pressure gradients of Ω=1 and Ω=20. In addition, the reduction of aspect ratio of microchannel section leads to the increment of critical Hartmann number in a specified lateral electric field. At the end, thermal analysis is being done by consideration of the effects of magnetic and electric fields on the Nusselt number.

Hossein Seyedzadeh Hossein seyedzadeh

The impact of school-based physical activity programs on academic performance among adolescents in india

Background: Evidence has suggested that school-based physical activity programs (SBPAPs) including structured physical education, extracurricular sports, and activity-based learningenhance memory and other cognitive functions. However, evidence on whether Indian adolescents can achieve improved cognition or increased academic performance also remains scarce. This study aimed to examine the relationship between SBPAPs and academic performance among Indian adolescents. Methods: A cross-sectional, mixed study was carried out from October 2024 to March 2025 in public and private secondary schools in Haryana and Punjab, north India. A total of 300 students aged 13 to 17 years were divided into an intervention group (n = 150) who participated in structured physical activity (PA) of at least 150 minutes per week and a comparison group (n = 150) who were involved in less than 30 minutes of PA per week. Academic performance was assessed in terms of composite scores of core subjects, while the level of PA was measured using the Physical Activity Questionnaire for Adolescents. Independent samples t-tests, one-way analysis of variance (ANOVA), and Pearson’s correlation analysis were all used for quantitative data handling. Qualitative data gathered from focus group discussions and key informant interviews with a subsample (n = 30) were thematically analyzed. Results: There were no significant differences in baseline demographics between the groups (p > 0.05). Compared with the comparison group, the intervention group showed significantly higher academic scores (mean = 76.4%, SD = 7.8; mean = 70.6%, SD = 8.4) with a moderate-to-large effect size (t = 6.30, p < 0.001, d = 0.72). A one-way ANOVA found that academic performance differed significantly among PA intensity levels (F(2,297) = 19.44, p < 0.001). There was a moderate positive correlation between PA levels and academic achievement (r = 0.44, p < 0.01). Qualitative findings corroborated quantitative data, showing that physically active students displayed improved concentration, emotional regulation, and academic motivation. Conclusions: Partaking in structured SBPAPs significantly increases Indian adolescents’ academic performance. These findings imply the necessity of including physical education in the academic curriculum as a low-cost, scalable method for supporting both cognitive growth and educational achievement.

Karishma Karishma

Privacy and security implementation in existing cloud based electronic health records - a detailed review

Over the recent years, cloud computing has emerged as a powerful means for providing automated healthcare facilities. Cloud helps in massive sharing of information between doctors and hospitals using Electronic Health Records. This major transformation has changed the way doctors and hospitals deliver quality and effective service to their patients. Using Cloud storage inhealthcare services has revolution- ized health industry, making it more efficient. Apart from the primary driving factors of cloud like flexibil- ity in cost of maintenance, infrastructure and development, on-demand scalability of storage centers and pay on use schemes are proven to be most effective. More and more digitalization of data causes breech of security and privacy.Because healthcare information is a highly sensitive data which cannot be com- promised,the future of healthcare relies in providing secure and trustworthy sharing of data by safe- guarding privacy and trust. This paper gives an extensive review of the existing security mechanisms for Cloud based healthcare systems.

Dr.c.priya

Dr gedam kamalakar cv

Dr. G. Kamalakar, Pursuing Post-Doctoral Fellow ICSSR, Research Assistant, ICSSR Major Research Project, Department of History, Dr. B.R. Ambedkar Open University. with a Ph.D in Political Science. He is awarded Doctorate by the Osmania University, Hyderabad, for the thesis on “WTO and GATS: Implication for the Indian Higher Education”. He is the recipient of RGNF Fellowship from the UGC and Pre-Doctoral Fellowship from OUCIP. He worked as a guest faculty at City College, Hyderabad and as a Counselor at Ambedkar Open University. He has written 3 books and edited 4 books and also published research articles in 17 UGC care list Journals. He also reviewed 11 Books and published them in UGC care list journals and sage publications. He received 7 awards including Amazing Grace Award, Pride India Award, Dr.B.R. Ambedkar Excellency Award, International Research Excellence Award, Dr. A.P.J. Abdul Kalam Life Time Achievement National Award, National best Teacher Award and Vidya Bharati Award. He presented research papers in more than 24 International, National Conferences and seminars. He has published thematic research papers in 13 National and 30 International Level Peer Reviewed / Refereed Research Journals He is also the Assistant Editor to an International journal and a Member of Editorial board & Reviewer for National and International journals published from 20 countries like USA, Turkey, Syria, UK, Pakistan, China etc. and has membership in 4 various associations.

Dr Gedam Kamalakar Dr gedam kamalakar

Identification of bioactive compounds and toxicity study of araucaria columnaris bark extract on human embryonic kidney cell line

Plants produce a diverse range of bioactive compounds making them a rich source of different types of medicines. Ornamental plants are cultivated for adornment and to enhance the appearance of houses and also for commercial purposes. However, only very few of these ornamental plant species have found to be used in medicine and only little literature exit on their chemical and biological actions. In the present study, the evaluation of antimicrobial activities and identification of bioactive compounds using TLC and GC-MS of the A. columnaris bark extract were performed. In GC-MS bioactive compounds with medicinal value were identified, such as Benzoic acid, 1H-N-Hydroxynaphth (2,3) imidazole-6,7-dicarboximide, 2-Propenoic acid, 3-(4-methoxyphenyl), 1H-N-Hydroxynaphth (2,3-d) imidazole-6,7-dicarboximi. To prove the nontoxic nature of the plant, its crude bark extract was subjected to toxicity study using human embryonic kidney cell line. It reveal that the plant is minimal toxic to the human kidney cell line so usage of appropriate level will found to be safe and also carrying out some structural modification will help in the extraction of new drugs for pharmaceutical purpose.

Dr. SARANYA DEVI K Dr. saranya devi k

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