Background: Hospital acquired infections (HAIs) are infections that patients acquire while receiving treatments for other conditions. Studies have shown that stethoscopes and sphygmomanometers can act as potential sources of these infections in patients accessing treatment in healthcare facilities. This study aimed to increase awareness among health workers in Nigeria of the potentials of stethoscopes and sphygmomanometers to transmit HAIs. Methods: Moist swab sticks were used to collect samples from 38 randomly selected stethoscopes and sphygmomanometers from some departments of four district hospitals. Collected samples were cultured using standard microbiological techniques. In addition, self-designed questionnaire was used to assess the knowledge and practice of doctors and nurses on the roles of stethoscopes and sphygmomanometers in HAIs. Results: About 83.8% of the health workers demonstrated some awareness of the roles of stethoscopes and sphygmomanometers in HAIs. 42.5% cleaned their stethoscopes, while 5% their sphygmomanometers. Staphylococcus aureus, (65.9% of stethoscopes), proteus mirabilis, Pseudomonas aeruginosa (67.6% of sphygmomanometers), Streptococcus and Coliform species were isolated. There was no significant difference between the contamination of stethoscopes and sphygmomanometers by the isolates, except for Pseudomonas aeruginosa (t=3.49, p=0.04). Conclusions: Awareness did not match practice in cleaning the stethoscopes and sphygmomanometers in the four facilities. Staphylococcus aureus and Pseudomonas aeruginosa were the two most common organisms isolated with a significant difference (t=3.49, p=0.04) between stethoscopes and sphygmomanometers in isolation of Pseudomonas aeruginosa. To curb HAIs, health workers need to improve on their practice of cleaning stethoscopes and sphygmomanometers.

Emmanuel umegbolu

Parkinson’s disease (PD) is one of the most common neurodegenerative disorders worldwide. It is mainly associated with a loss of dopaminergic neurons in the substantia nigra pars compacta

Nagarjuna narayanasetti

The notable developments in renewable energy facilities and resources help reduce the cost of production and increase production capacity. Therefore, developers in renewable energy evaluate the overall performance of the various equipment, methods, and structure and then determine the optimal variables for the design of energy production systems. Variables include equipment characteristics and quality, geographical location, and climatic variables such as solar irradiance, temperature, humidity, dust, etc. This paper investigated and reviewed the current big data methods and tools in solar energy production. It discusses the comprehensive two-stage design and evaluation for examining the optimal structure for renewable energy systems. In the design stage, technical and economic aspects are discussed based on a robust analysis of all input/output variables for determining the highest performance. Next, assess and evaluate the effectiveness of each method under different circumstances conditions. Then convert each qualitative indicator into a quantitative measure using extensive data analysis methods to determine the overall performance of the various qualitative variables. The paper also provides an in-depth analysis of the mathematical techniques used in measuring the efficiency of the renewable energy production system and discussing future axes of work in the field of specific energy.

Acaa pub

This study investigated utilization of information communication technology for the improvement of personnel economics in the administration of public secondary schools in Rivers state. The study had two objectives, with corresponding research questions and hypotheses. A descriptive survey design was employed, and the population consisted of 11,258 secondary school teachers from 258 public senior secondary schools in Rivers state, with 4,127 males and 7,131 females. A sample of 383 teachers (163 males and 220 females) was drawn from 15 public senior secondary schools using the Taro Yamane Formula and a two-stage sampling technique of stratified and simple random sampling. Data was collected using a self-structured questionnaire titled "Utilization of Information and Communication Technology and Personnel Economics in Secondary School Administration." The questionnaire underwent face and content validation by three experts and demonstrated good reliability with a Cronbach Alpha coefficient of 0.82. Research questions were answered using mean and standard deviation, while inferential statistics utilized the z-test. The findings indicated a significant difference between male and female teachers in their perceptions of ICT utilization for teachers' supervision and evaluation, highlighting the potential for ICT to improve personnel economics in the administration of public secondary schools in Rivers state. Based on these findings, it can be concluded that implementing various ICT-based strategies such as developmental supervision, contextual supervision, clinical supervision, and collaborative forms of developmental supervision could enhance the effectiveness of teaching staff and overall school productivity in public secondary schools in Rivers state.

Fxintegrity publishing

To test and popularize the Krishi Vigyan Kendra, Barmer-II, Gudamalami, Rajasthan recommended Enhance the Productivity of Ridge gourd (Luffa acutangula L.) Cultivation in Net Trellis System in Barmer District of Rajasthan, On Farm Trials (OFT’s) were conducted during the kharif season of 2019 and 2020 in farmers participatory mode at three locations in Barmer District of Rajasthan. The experiment consisted of two treatments viz., recommended practice (Net trellis system) and farmers practice (Furrow). Net trellis system had significant increase number of picking (13), fruit length (43.33 cm) and fruit weight (210 g) as compared to farmer’s practice (07, 22.67 cm and 101.5 g) during both the year as well as pooled data. The two year average fruit yields of net trellis system have shown doubled production over farmers practice method. Net trellis system was recorded increase yield for 73.57% (138.06 t/ha) as compared to farmers practice (79.54 t/ha) during both the year as well as pooled data. Similarly, the net returns and B:C ratio also revealed that maximum under net trellis system during both the year as well as pooled data Rs 232790 per hectare and 3.36:1 as compared to farmers practice Rs 89913.5 per hectare and 2.30:1. Net trellis system had significant reduce the damage of pest and soil borne diseases and improve the quality of fruits

Dr. babu lal jat

Background: COVID-19-positive patients are at increased risk of adverse clinical outcomes, with type 2 diabetes cohorts at substantially higher risk compared to the general population. The additional role of diabetic and non-diabetic polypharmacy in these patients' clinical course has remained unexamined. In this study we have comprehensively examined the role of polypharmacy in the determination of mortality outcomes in patients with COVID-19 clinical syndrome. Methods: We retrospectively examined case notes and electronic records of N = 497 patients with type 2 diabetes and COVID-19 infection. We ascertained the number of medications each patient was taking and used this to categorize the study cohort into diabetic [n = 246] (5 or more diabetic medications), and non-diabetic polypharmacy [n = 251] (5 or more non-diabetic medications). The primary outcome was the need for intensive care admission between the two groups. Results: In patients with “non-diabetic polypharmacy” (>5 medications), advancing age, and higher HBA1c levels, were associated with increased risk of Intensive care admission (OR 1.06 [CI 1.03-1.07], P = <0001), (OR 1.01 [CI 1.01- 1.20], P 0.017), respectively. Patients taking 5 or more non-diabetic medications had an increased likelihood of admission into the intensive care unit compared to those on lower medication thresholds (OR = 1.7; CI = 1.1 to 1.3; p-value = <0.0006). Conclusion: In an inpatient cohort of type 2 diabetic patients with COVID-19, non-diabetic polypharmacy was associated with a multiplicative risk of intensive care admissions. This will necessitate the need for periodic medication reviews in these cohorts of patients to mitigate these potential risks and improve clinical outcomes.

Karishma

In today’s ever-changing world with new advancements, Customer Experience or CX plays a critical role in a value proposition, thereby affecting customer loyalty, top-line metrics and business growth. Artificial Intelligence (AI) is becoming very important because AI provides adequate, rapid, and smooth Mass-Customized interactions. Self-checkout to virtual assistants, current innovation reveals how tools supported by Artificial Intelligence increase customer-centric experience, helping to decipher and estimate the customer’s wants and needs in real-time. Thus, this paper focuses on the revolutionary impact of AI in recasting customer experience management initiatives, which includes understanding AI applications in customer marketing, customer service, customer emotion analysis, and prediction of the probable behavior of customers. By means of AI, organizations can design and deliver unique experiences for their customers, fine-tune contacts, and improve satisfaction, loyalty, and customer retention. This article thus presents a critical discussion of prior and current literature on AI and customer experience and the research methodology adopted for assessing AI quality in improving CX innovations. It expounds on results from recent case studies on the value of integrating AI. It is not a matter of whether customer experience will be powered by AI, but when and by how much, as customer data drives decisions, interactions with customers, and learning in near-real time. Therefore, as AI technologies advance, companies adopting AI in customer experience approaches will close distance or gain ground on their competitors since they will efficiently offer superior, preemptive and personalized experiences.

Mohan krishna mannava

ABSTRACT- Objective- The principal objective of the present investigation was the preparation of several analogs to further evaluate the binding site hypothesis. Aryl semicarbazides have also been reported to display excellent anticonvulsant activity in mice and rats. Method- In this project, the synthesis of semicarbazone derivatives was carried out. All molecules were synthesized using the common starting material –aniline. In all compounds, an intermediate was first formed by substituted phenyl urea using substituted aniline and potassium cyanate, and then it was hydrolyzed to get substituted phenyl semicarbazide, which was directly coupled with ketones. All the synthesized compounds were biologically screened for their anticonvulsant activity by the MES method. Result- Standard error mean was calculated concerning standard and control drug, Phenytoin sodium (25mg/kg.) and DMSO. The synthesized semicarbazone was characterized by using IR Spectroscopy. One another representative molecule compound was characterized using 1H NMR Spectroscopy. Conclusion- It can be concluded that designed semicarbazones were synthesized and characterized successfully. After synthesis of designed semicarbazones compounds were evaluated for anticonvulsant activity. Finally, two compounds have shown better activity in comparison to the other molecules.

Ajay garg

Vigna trilobata (L.) VERDC. belongs to the family Papilionaceae, which is found throughout the tropical and warm temperate regions of the world. In folk medicine, it is used for arthritis, fever, cough, dysentery, and urinogenital disorders. Different secondary metabolites, such as alkaloids, glycosides, terpenoids, and flavonoids, have been reported in Vigna trilobata. It has antioxidant, antidiabetic, and anti-inflammatory activities.

Dr. salman ahmed

HIV/AIDS cases in Indonesia continue to increase and have spread to all provinces in Indonesia. Bandung is one of the cities with a high number of people living with HIV/AIDS in Indonesia. As one of the areas with the highest number of reported HIV cases, the Bandung city government seeks prevention and treatment through the role of existing stakeholders. However, stigma and discrimination against people living with HIV & AIDS, now referred to as PLHIV, are still found and are difficult to eliminate. People diagnosed as contaminated with the HIV & AIDS virus often get a negative stigma. This study aims to analyze how to remove the stigma and discrimination of people with HIV/AIDS through the role of civil society. The research results show that stigma against HIV is often directed at certain minority groups and is often associated with morals and religion. Meanwhile, discrimination against people with HIV is manifested in violations of individual rights in the economic, social, and cultural spheres. The issue of stigma and discrimination against PLWHA has not received serious attention. Therefore, the role of civil society is very important because it can open a dialogue with the community regarding HIV/AIDS to dispel myths that tend to discriminate against PLHIV.

Syahrul tuba

The purpose of this study is to explore the impacts of foreign cartoons programs on the social behavior and attitude of Pakistani Children. It is forecasting different cartoon programs 24/7; hence, children spend most of their leisure in front of the television. All these cartoon characters affect the social life and psyche of the children and induce positive and negative mannerism in their daily lifestyles. It has found that one of the most disturbing factor is that the ferocity in children today is increasing rapidly due to following their favorite violent cartoon characters which are even different from their culture and societal norms. The issue is violence is what they see in every cartoon program in one or the other way. Their Guardians are unaware that these cartoons they let their children watch are destroying their parenting as negative forces are attacking the innocent minds of this generation. The study gives the insight of why and what is happening with non-parametric statistics studied and used for thorough analysis. The behavioral outcome of the kids like, imitating their preferred animation character, utilizing various dialects, watching the TV as opposed to deciding on outdoor games and being difficult about getting precisely the same outfits and embellishments as their adored character. This contextual analysis features the disturbing circumstance that guardians are uninformed of. There is something other than mimicking the particular character. The only traits of watching these foreign cartoon characters is that it might damage their own customs and they wildly become to believe these characters as their role models.

Zaki hasan

Family businesses must harness the full potential of their human resources and maintain employee loyalty to achieve the companies’ objectives effectively. This study examines the influence of transformational leadership on employee commitment through work-life balance and workplace social support. The research was conducted from August to December 2023 using an online questionnaire distributed to employees in a family firm in Medan, Indonesia. The data were then analyzed using PLS-SEM. The results show that transformational leadership significantly effects employee commitment, work-life balance, and workplace social support. However, although workplace social support mediates the relationship between transformational leadership and employee commitment, work-life balance fails to do so. It was also found that work-life balance has no direct influence on employee commitment. Using an IPMA analysis, this study highlights the importance of transformational leadership and workplace social support in the family business environment. Transformational leadership has also been shown to have the best performance and effect on employee commitment. Managers should prioritize these aspects to reduce employees’ stress levels, improve psychological well-being, and increase job satisfaction, leading to a more committed, high-performance workforce.

L

Epithelial cells, lining the skin and internal organs, play a crucial role as protective barriers and regulators of substance transport. Traditionally, these cells were not considered to employ electrical signaling for communication. However, recent investigations have unveiled that epithelial cells generate slow electrical signals, termed the "silent scream," in response to injury, thus challenging conventional views of intercellular communication. A recent experimental investigation provided compelling evidence for this phenomenon, demonstrating the ability of these cells to transmit electrical signals over considerable distances within the epithelium. The research utilized microelectrode array chips to precisely detect subtle electrical events in keratinocytes and Madin-Darby Canine Kidney (MDCK) cells, revealing spiking activity characterized by slow propagation speeds, distinct from the rapid action potentials of neurons. The mechanisms underlying this novel signaling are explored, focusing on the involvement of mechanosensitive ion channels, calcium signaling, and Adenosine triphosphate (ATP) release. Calcium ions, well-established intracellular messengers, appear to play a central role in this biological phenomenon. Integrating this newly discovered communication mode into the existing understanding of skin cell biology reveals a more intricate picture of how skin senses and responds to its environment. The implications of this finding extend to various facets of skin physiology and pathology, including wound healing, inflammation, and skin aging. In wound healing, where endogenous electric fields guide cell migration and promote repair, this unique type of electrical signaling potentially plays a crucial part. Furthermore, aberrant electrical signaling might contribute to chronic inflammatory conditions, and age-related changes in this signaling could underlie the functional decline observed in aged skin. The potential for other environmental stressors to trigger the epithelial-generated electric signals also warrants investigation. The exploration concludes by discussing potential technological applications, such as bioelectric sensors and enhanced wound healing therapies, and future research directions aimed at further elucidating the molecular mechanisms and functional roles of this non-excitable cell electrophysiology.

Karishma

This study investigated the formulation, implementation, and performance implications of an artificial neural network–particle swarm optimization (ANN–PSO) based energy scheduling framework for a 150kW hybrid micro-grid. The analysis focused on two hybrid configurations, namely micro gas turbine–fuel cell (MGT–FC) and solar photovoltaic–battery storage system (PV–BSS), with emphasis on optimal dispatch behaviour and system efficiency under dynamic load and generation conditions. MATLAB was used to simulate ANN-based forecasting of hourly load and distributed energy resource outputs, which were subsequently optimized using PSO over multiple iterations to achieve balanced supply–demand scheduling. 4-in-1 visualization techniques were employed to capture convergence behaviour, transient response, dispatch stability, and efficiency dynamics across operating scenarios. Results showed that both hybrid systems achieved convergence within 20–24 PSO iterations, with scheduled power maintained within 50–120kW despite injected disturbances of ±20–30kW. The MGT–FC configuration demonstrated smoother dispatch profiles and faster fitness convergence, while the PV–BSS system exhibited greater variability due to intermittency, compensated by storage dispatch. Efficiency analysis revealed that optimal ANN–PSO scheduling sustained MGT–FC efficiency within 83–89%, whereas PV–BSS efficiency ranged between 41–72%, peaking during high-irradiance periods. Overall, the findings established that ANN–PSO-based scheduling enhanced operational stability and efficiency in both configurations, while highlighting the superior resilience of the MGT–FC hybrid under identical dynamic conditions. The study concluded that intelligent optimization provides a viable pathway for improving micro-grid performance in developing communities and industrial off-grid applications, where reliable and efficient decentralized power supply remains critical. It was therefore recommended among others that power system engineers and industrial energy planners in developing economies adopt ANN–PSO frameworks for real-time micro-grid dispatch to improve efficiency, resilience, and adaptability of decentralized energy systems serving communities and industrial loads.

Fxintegrity publishing

Thrombocytopenia is a recurrent hematological disturbance in pregnancy. In pregnant women with thrombocytopenia, the risk of excessive bleeding during or after child-birth is high, particularly when they require a cesarean section, other surgery during pregnancy, labor or in the puerperium period. The objective of this study was to assess the prevalence of thrombocytopenia among pregnant women attending antenatal care service at Tripoli University Hospital, Libya. A cross-sectional analysis was used to determine the prevalence thrombocytopenia in pregnant women attending prenatal care services from July to December, 2020 at Tripoli University Hospital. A structured pretested questionnaire was used to obtain socio-demographic data, nutritional factors, obstetrics and gynecological factors, history and clinical conditions. Venous blood samples were collected for platelet count and other platelet parameters, which determined by using Sysmex automation. A total of 72 participated women; about 40%, 35% and 259% of the participants were in the third, second and first trimester, respectively. The mean number of children that women have was 2, with 2.7% having just one child and 47% having three or more children. This study concluded that the prevalence of thrombocytopenia and mostly with mild form is 8.3% and as being greater among pregnant women living in rural areas. Health care providers should do thrombocytopenia test regularly for every pregnant woman in order to prevent excessive bleeding during pregnancy, especially whom living in rural areas.

Mediterranean journal of pharmacy and pharmaceutical sciences

A Novel route one-pot three-component reaction was developed for the synthesis of 2,3-Dihydro-2-phenyl-1- H-Naphtho-[1,2-e] [1,3] Oxazine by using Substituted Aniline, Formalin & β-Naphthol in the presence of Tannic acid (10 Mol %) as catalyst. The reaction is observed by using TLC, after completion of reaction product is characterized by 1H, NMR, 13C NMR, IR and Mass Spectra.

Dr.prashant kumdale

The Secret Language of Birthdays: Your Complete Personology Guide for Each Day of the Year by by Goldschneider, Gary, Elffers, Joost (Paperback) This The Secret Language of Birthdays: Your Complete Personology Guide for Each Day of the Year book is not really ordinary book, you have it then the world is in your hands. The benefit you get by reading this book is actually information inside this reserve incredible fresh, you will get information which is getting deeper an individual read a lot of information you will get. This kind of The Secret Language of Birthdays: Your Complete Personology Guide for Each Day of the Year without we recognize teach the one who looking at it become critical in imagining and analyzing. Don’t be worry The Secret Language of Birthdays: Your Complete Personology Guide for Each Day of the Year can bring any time you are and not make your tote space or bookshelves’ grow to be full because you can have it inside your lovely laptop even cell phone.

Kamal singh

Urolithiasis is a common worldwide problem with high recurrence. This review covers thirteen (13) antiurolithiatic plants of the family Boraginaceae, twenty (20) from Brassicaceae, twenty-three (23) from Malvaceae and twenty-four (24) from Poaceae used globally in different countries. Hopefully, this review will be helpful for the general public and attract the scientific world for antiurolithiatic drug discovery.

Dr. salman ahmed

The study was conducted on glass slides to observe the growth patterns of urinary calcium oxalate monohydrate crystals and their inhibition using 5, 10 and 15% Phaseolus vulgaris seed infusion. For this purpose, a drop of gel medium (sodium metasilicate of 1.06 specific gravity and 3M acetic acid solution) at pH 5.02-5.17 was placed in the middle of the glass slide and converted into gel. A single drop of 1 M oxalic acid was dropped to the left, and 1 M calcium chloride and magnesium acetate (1:1) solution fell to the right side of the adequately formed gel. The glass slide was observed under microscope till it was completely dried. In the case of the crystal inhibition study, a drop of Phaseolus vulgaris infusion was also added on the right side just after adding calcium chloride and magnesium acetate solution. The results without infusion showed detailed morphology and aggregation patterns of observed crystals as donut, dumbbells, needles, platy, prismatic, rosette, round edges, and loose and compact aggregates. All infusions of Phaseolus vulgaris showed defective crystals. 5 % infusion inhibited crystals of all morphologies with their loose and compact aggregates except rosettes. Whereas 10 and 15 % infusion converted the rosette crystals into ineffective calcium oxalate dihydrate crystals of tetragonal bipyramidal and elongated rod shape. The microscopic study of calcium oxalate crystal growth and its inhibition is simple and provides rapid qualitative analysis of antiurolithiatic activity.

Dr. salman ahmed

The daily water distillation of the single basin conventional solar still is limited. In the present work, experimental analysis of a parabolic disc type solar still and conventional solar still are investigated. The solar radiation is focused to the single point to produce higher basin temperature. The water is flown continuously inside the copper receiver to utilize the incident solar radiation. The hourly readings were taken to analyze the thermal performance of the parabolic disc type solar still and conventional solar still. The water collection of parabolic disc type solar still is increased about 40% over conventional solar still.

Appadurai m