This exploratory case study employed Appreciative Inquiry Framework in answering the following questions: 1) What are the expectations set by the following to the student homosexuals; a) Self, b) Parents and c) Teachers; 2. What are the positive and negative effects of these expectations to the student homosexuals? and 3) How do these expectations affect the process of identity development of the student homosexuals?. The participants are five college students who identified themselves as homosexual. Written consent was secured to ensure that the research abides to the ethical standards. The data was triangulated through analysing the point of view of the student participants, their parents and their teachers. Results revealed that expectations set by the student homosexuals, their parent and teachers are all contributory factors that affect the identity development of student homosexuals. Moreover, it was revealed that those who have problems in their identity development experienced difficulties in their performance in school. Positive and negative effects of expectations were also noted as the participants shared their stories. With the results, it was recommended that teachers must treat all their students equally regardless of their gender preferences in life. Activities that support the holistic personalities of students must be given emphasis. The parents must support their children in whatever endeavour they take and provide them guidance to be successful in their academic pursuits. Lastly, a model of counselling procedure for student homosexuals was proposed.
2-Pyrazolines are well known, and important nitrogen-containing five-membered heterocyclic compounds which belong to the family of azoles and have been found to possess considerable activities, like anticancer, antibacterial, antifungal, immunosuppressant and antiamoebic activity. In the present work, ten novel pyrazolines were prepared from chalcones, characterized and evaluated for their antibacterial activity against Staphylococcus aureus and Escherichia coli using Ciprofloxacin as standard and using DMSO as a solvent. Their activity was evaluated by measuring the zone of inhibition in mm. All the compounds exhibited antibacterial activity against Staphylococcus aureus and Escherichia coli. Among ten derivatives of compounds synthesized, the derivative with 2-chloro and 4-chloro substituted phenyl rings attached to pyrazolines exhibited the highest activity against both types of organisms. The derivatives with an unsubstituted phenyl group attached to pyrazolines exhibited comparatively less activity. Thus it can be concluded that pyrazolines containing substituted phenyl groups are effective broad spectrum antibacterial agents, and they can be developed as effective antibacterial agents.
This proposed work is used to optimize the costs of exceptional elements of machine cells for a variety of components in changing environments to have reduced material movements in cell layout. The exceptional ele¬ments are eliminated in the optimization model by doing machine duplication and part subcontract. Then the shop floor layout is designed to have optimized material movements between cells and within a cell. The result of a linear programming optimization model is cost savings, machines duplicated, parts subcon¬tracted, inter intracellular movements. Finally, the output of the inbound facility design is the floor layout which has machine cell clusters with optimized floor areas. The optimization model is provided with budg¬etary constraints for duplication and the economic tradeoff between machine duplication and part subcontract. Cell layout is prepared to reveal the saving in floor area and material movement lengths than in process layout with the help of distance matrix and dimensions of cells.
The current study is carried out to evaluate the antiemetic activity of methanol extracts of five leguminous plants leaves viz., Cassia siamea Lamk., Cyamopsis tetragonoloba Taubert., Delonix regia Rafin., Samanea saman Merr. and Vigna trilobata Verdc. at a dose of 150 mg/kg body weight orally, using a chick emesis model. Emesis was induced in male chicks by the oral administration of copper sulphate (50 mg/Kg body weight). The antiemetic activity was determined by calculating the mean decrease in the number of retching as compare with the control. All the extracts showed antiemetic activity when compared with standard drug chlorpromazine (150 mg/kg body weight orally). Among all extracts, Delonix regia showed the highest (96.74%) and Cassia siamea lowest (18%) antiemetic activity.
Le 05 décembre 2012, les pratiques et expressions culturelles liées au balafon des communautés sénoufo du Mali, du Burkina Faso et de la Côte d’Ivoire ont été inscrites sur la Liste représentative du patrimoine culturel immatériel de l’humanité. Le tafal-djéguélé est une pratique et expression culturelle liée au balafon des Sénoufo de Côte d’Ivoire. Deux raisons principales fondent son usage : amener les laboureurs à la houe à se surpasser d’une part, et magnifier les valeurs des senambélé1 d’autre part, notamment celles en rapport avec le labour étant donné que le sénoufo est agriculteur par essence. Toutefois, en raison de certains changements sociaux, le tafal-djéguélése pratique de moins en moins. Cette situation prive le senanw d’aujourd’hui d’un cadre majeur d’enseignement et de diffusion de valeurs, et pose ainsi la question de leur transmission aux générations actuelles et futures. Cet article vise à démontrer comment la faible pratique du tafal-djéguélé empêche de nos jours la transmission de "valeurs- références" en pays sénoufo, mais aussi à proposer des pistes de solutions.
A mental and behavioral illness is described as a clinically significant illness with changes in thought, emotion, or behavior related to a personal situation. Objectives of the study: To assess the knowledge regarding mental health & illness and level of stress. 2. To determine the effectiveness of Educational Intervention on knowledge regarding mental health & illness and level of stress 3. To find out the association between pre-test knowledge level on mental health & illness and selected demographic variables. 4. To find out the association between pre-test stress level and selected demographic variables. 5. To find out relation between knowledge score of mental health & Illness with stress level. Methodology: Quantitative research approach with pre-experimental research design was used. Sampling: 300 samples was chosen with consecutive sampling technique. Result: In pretest mean score for knowledge and stress were 8.9 and 27.9 respectively and post-test were 19.7 and 17.45 which showed that education intervention improve the knowledge and decrease stress among adolescent. Improved knowledge reduces stress level. Conclusion: Educational intervention improve knowledge level which significantly reduce level of stress.
Viral hepatitis is one of the main public health concerns around the world. Even though infection management techniques have been implemented over the last few decades, eradication or significant reduction has remained a mystery. The purpose of this study is to look into the prevalence of acute infectious hepatitis in the East of Libya and how the type of virus, age, gender, clinical manifestations, and outcome are related. This is a hospital-based retrospective study. The data on the frequency and distribution of viral hepatitis based on age, gender, seasonal, clinical, and ultrasound findings, and the outcomes during a period of two years from January 2020 to December 2021 were collected and analyzed. Of the 0.39% (72 cases) of total hospital admissions (18340) under the age of 15 years old for acute infectious hepatitis patients, the most common age group was 5-12 years (79.6%). Winter accounted for 41.6% of all the cases. Females made up 65.3% of the cases. Jaundice was the most prevalent presentation (87.5%). Hepatomegaly was seen in 83.3% of the patients. Most of the cases have mild hyperbilirubinemia (5-9 mg/dL, 75.0%). Approximately 1/5th of the patients' serum glutamic-oxaloacetic transaminase (SGPT), and nearly 1/3rd of the patients' SGPT levels were in the range of 1000-2000. One patient's hepatitis C was positive, one patient's hepatitis B was positive, and 97.2% were positive for hepatitis A. 88.8% of the individuals recovered without complications, whereas 11.1% showed symptoms of hepatic failure but recovered. The present study indicates that acute hepatitis A is more prevalent, especially in the winter. Those who are females and 5-12 years of age were more affected by acute viral hepatitis in Libya.
Mediterranean journal of pharmacy and pharmaceutical sciences
Autophagy is a self-digesting mechanism responsible for removal of damaged organelles, malformed proteins during biosynthesis, and nonfunctional long-lived proteins by lysosome. Autophagy has been divided into three general types depending on the mechanism by which intracellular materials are delivered into lysosome for degradation that is, microautophagy, chaperone-mediated autophagy (CMA), and macroautophagy. In microautophagy cytoplasm material is sequestered through direct invagination to the lysosomal membrane. Whereas in CMA proteins flagged with pentapeptide motif (KFERQ) were selectively degraded through direct translocation into lysosome. Macroautophagy involves the formation of subcellular double-membrane-bound structures called autophagosomes that contain degradable contents of cytoplasm materials and deliver them into lysosomes for breakdown by lysosomal enzymes. The molecular mechanism of autophagy involves several conserved Atg (autophagy-related) proteins. Systems produce modified complexes Atg8-PE and Atg5-Atg12-Atg16 as autophagy regulators. Autophagy is activated in response to diverse stress and physiological conditions. For example, food deprivation, hyperthermia, and hypoxia are mediated by factors like insulin/IGF-1, m-TOR signaling, FOXO transcription factors, and chaperones. The perturbance in autophagy may lead to several types of cancers, myopathies, and neuromuscular disorders. Several autophagy inducers and inhibitors like 3-methyladenine (3-MA), bafilomycin A1, LY294002 (LY), and Velcade have been used to treat disease is an intense field of study.
This Document addresses the main trends around healthy eating in the global, Latin American, and Peruvian environment related to the proposed business plan. Analysis shows that with an increase in the population around the world it is important for food producing organizations to introduce new food products in order to be in the race of famous food brands. Based on qualitative and quantitative data from various sources, it is possible to know the opportunities for a plant-based burger business. This assignment aims to recognize if there is a favorable evolution for the proposal of this business plan at the different levels of the environment. The brand focused on this assignment in KFC. A plan for introducing green burgers in Peru and other regions of Latin America was developed in this paper.
Higher Education has an important role in the task of rebuilding a nation and it pavCes the way for overall development of a nation. The twentieth century has witnessed several revolutions like Green revolution, White revolution, I.T revolution, so on and so forth, taking human civilization to new heights. At the start of 21st century, we gave a lot of importance given to higher education. Every country realized the value of higher education and the benefits that accrue from it. “The social demands for higher education continue to increase. The inabilities of the state to support this growing demand result in new financing arrangements for higher education. The recent reforms in this area could be broadly divided into two categories: the privatization of public institutions and the establishment of private institutions of higher education. Privatization implies the application of market principles in the operation of public institutions, while ownership rests within the public domain. Promotion of the private sector implies the growth and expansion of the non-state sector in higher education, and very often this sector does not rely on state funding for its growth and expansion. Both of these measures have paved the way for market operations in higher education
This research was conducted at Al-Baitul Amien Elementary School Jember which aims to answer the problem 1) How is the concept of prophetic education in shaping the character of students in Al-Baitul Amien Elementary School Jember? 2) How is the implementation of prophetic education in shaping the character of students in Al-Baitul Amien Jember Elementary School? 3) How is the evaluation of prophetic education in shaping the character of students at Al-Baitul Amien Elementary School Jember? The method used in this research is qualitative research methods. The approach used is a descriptive qualitative approach. The results of this study indicate: (1) The concept of prophetic education in shaping the character of students at Al-Baitul Amien Elementary School Jember, namely: the formation of a distinctive curriculum based on the historical values ??of the mosque, religious habituation programs, and the commemoration of Islamic holidays. (2) Implementation of prophetic education in shaping the character of students in Al-Baitul Amien Jember Elementary School, namely: Dhuha Prayers, Dhuhr and Asr Prayers in Congregation, Asmaul Husna Habits, Tahfidz Qur'an, Juz 30 Hafalan Program, Tartil Qur'an, Tilawati Qur'an (Qiro'ah), Friday charity, Islamic Studies, Team of action / affection, Learning the Koran, PAI Subjects, Learning Arabic, Student Liaison and Achievement Books, Commemoration of Islamic Holidays, Sholawat and Hadrah, Nasyid, and Da'i Little. (3) Evacuation of prophetic education in shaping the character of students at Al-Baitul Amien Jember Elementary School, namely: a connecting book for reports on the implementation of student sunnah prayers, compulsory prayer services, student morals at home, and also letters from parents to teachers and vice versa. Penelitian ini dilakukan di Sekolah Dasar Al-Baitul Amien Jember yang bertujuan untuk menjawab permasalahan, 1) Bagaimana konsep pendidikan profetik dalam membentuk karakter peserta didik di Sekolah Dasar Al-BaitulAmien Jember? 2) Bagaimana implementasi pendidikan profetik dalam membentuk karakter peserta didik di Sekolah Dasar Al-Baitul Amien Jember? 3) Bagaimana evaluasi pendidikan profetik dalam membentuk karakter peserta didik di Sekolah Dasar Al-Baitul Amien Jember? Pendekatan yang digunakan adalah pendekatan kualitatif deskriptif dan jenis penelitian lapangan (field research). Teknik pengumpulan data menggunakan wawancara, observasi, dan dokumentasi. Dan keabsahan datanya menggunakan triangulasi sumber dan teknik. Hasil penelitian ini menunjukkan: (1) Konsep pendidikan profetik dalam membentuk karakter peserta didik di Sekolah Dasar Al-Baitul Amien Jember yaitu: Kurikulum dibuat berdasarkan nilai historis masjid, program pembiasaan keagamaan, dan peringatan hari besar Islam. (2) Implementasi pendidikan profetik dalam membentuk karakter peserta didik di Sekolah Dasar Al-Baitul Amien Jember yaitu: melalui kegiatan Sholat Dhuha, Sholat Dhuhur dan Ashar berjamaah, Pembiasaan Asmaul Husna, Tahfidz Qur’an, Program Hafalan Juz 30, Tartil Qur’an, Tilawati Qur’an (Qiro’ah), Jum’at beramal, Kajian Islami, Tim penindak/ afeksi, Pembelajaran Al-Qur’an, Mata pelajaran PAI, Pembelajaran Bahasa Arab, Buku Penghubung dan Prestasi Siswa, Peringatan Hari Besar Islam, Sholawat dan Hadrah, Nasyid, dan Da’i Cilik. (3) Evaluasi pendidikan profetik dalam membentuk karakter peserta didik di Sekolah Dasar Al-Baitul Amien Jember yaitu: buku penghubung laporan mengenai pelaksanaan ibadah sholat sunnah siswa, ibadah sholat wajib, akhlak siswa dirumah, dan juga lembar surat dari orang tua kepada guru maupun sebaliknya.
Worldwide, the focus on online learning during the era of the COVID-19 pandemic faced many challenges. The present study aimed to evaluate the preferences, perceptions, and attitudes of university students toward various strategies of learning. A pre-piloted cross-sectional survey was posted on the internet in Arabic and English language. Questions covered the demographical characteristics of the participants and their preferences and perceptions of various learning strategies. We received 270 questionnaires from various countries. The majority (n=199, 73.7%) of respondents were from the University of Sharjah, United Arab Emirates, with n=125 (46.3%) participants from the College of Pharmacy. The majority (n=198, 73.0%) of respondents were females, Arabs (n=262, 97.0%), living with their families (n=208, 77.0%), and with only the father working (n=174, 64.0%). Preference was, for online learning (n=145, 53.7%) as compared to in-class learning (n=119, 44.1%). More students (n=110, 40.7%) claimed improvement in their grades with online learning but 62 of students (23.0%) stated that their grades were worsened. Student’s performance in online exams was similar to that in paper exams. The majority (n=168, 62.2%) of students claimed that their overall expectations of online learning were not the same as those for in-class learning. 50.0%-60.0% of respondents believed that in-class learning allows them to learn more effectively, and achieve the best work preparation, best exam performance, and best education value, and they were more likely to recommend it. Despite the disadvantages of online learning, it remains the future strategy for higher education. Appropriate planning of courses, and helping students by reducing digital inequity, if any, would certainly prove satisfactory for the millennial generation of students
Mediterranean journal of pharmacy and pharmaceutical sciences
Cet article s’intéresse à la fréquence, aux fonctions de l’alternance codique chez l’enseignant d’espagnol en classe de quatrième (débutants) et aux activités pédagogiques au cours desquelles apparaît ce phénomène de contact de langue. Notre investigation porte sur 80 enseignants d’espagnol et 1000 élèves hispanophones de la région de San Pedro en Côte d’Ivoire. Pour ce faire, nous avons opté pour l’analyse quantitative et qualitative. La première méthode par le biais du logiciel SPSS a permis de constituer une base de données. Ainsi, il ressort que 51 soit 63,1% des enseignants utilisent 5 à 10 % du temps du cours pour s’exprimer en français. Aussi, ces enseignants alternent-ils plus ces deux langues pendant les activités de compréhensions de texte, et vocabulaire soit 32,1% de l’effectif. Quant à l’analyse qualitative de type conversationnel, elle a servi à proposer quelques fonctions d’alternance codiques pendant les activités d’interaction.
Potassium Bromate (KBrO3) is an oxidative agent capable of causing hematological alterations and other toxic effects. Amaranthus Viridis (Inine) is a medicinal plant traditionally used for various therapeutic purposes. This study investigated the ameliorative effect of ethanol extract of Amaranthus viridis (Inine) on the haematological parameters in potassium bromate (KBrO3) intoxicated Albino Rats. Thirty (30) rats divided into six (6) groups consisting of five rats each, group one as the normal control, group two as the negative control (50 mg/kg of KBrO3 only), group three Vitamin C (100 mg/kg) + 50 mg/kg of KBrO3and group four to six (200 mg/kg, 400 mg/kg, and 800 mg/kg) respectively. KBrO3 exposure significantly altered some haematological indices in the rats indicating a haematotoxic effects. The results showed a dose-dependent improvement in several haematological parameters upon coadministration of Amaranthis viridis occurred. The red blood cell count (RBC), packed cell volume (PCV), haemoglobin concentration (Hb), and white blood cell count (WBC) exhibited notable recovery in comparison to the KBrO3-treated group. Platelet count (PLT), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC) also demonstrated positive alterations in response to the extract. The group receiving the highest dose of the leaf extract (800 mg/kg) alongside KBrO3 displayed the most significant improvement in the aforementioned parameters, indicating a potential dose-dependent protective effect against KBrO3-induced haematotoxicity. These findings suggest the potential therapeutic efficacy of Amaranthus viridis extract in mitigating KBrO3-induced hematological alterations.
Regression modeling analyses the relationship between two or more variables and can be used to predict the response variable from one or more independent variables. The present study uses linear regression analysis to evaluate the growth in the two fish species of genus Oreochromis, Nile tilapia and Jipe tilapia, under aquaculture conditions. The models were fitted using a collection of functions in the R-software library. The final models were selected using the goodness of fit criteria based on the coefficient of differentiation, the model p- values and Akaike information criteria. The significance of the linear relationship between predictor variables and the mean response was tested by comparing the computed standardized parameter estimates, whereas the confidence intervals were constructed to assess the uncertainty of predicting the response variable and determine outliers in the model. Generally, both species exhibited good condition during growth and all the measured water quality variables significantly afffected growth (p<0.05). However, only temperature and dissolved oxygen produced the most important linear relationship with fish weight. The study recommends that data from a controlled experiment should be used the determine the interactions between the two growth variables.
The need for natural medicine and nutrients from natural product sources cannot be overstressed. Plant parts like leaves, stem, root, seed, nut and flowers supply enormous minerals, phytochemicals and other bioactive constituents apart from the primary metabolites. Terminalia Catappa (T. catappa) is a combretaceous plant often found in tropical and subtropical regions. The plant has many uses as an ingredient of various drugs such as anti-oxidants, anti-inflammatory, anti-cancer, and anti-diarrheal. Thus, the main objective of this study was to determine the proximate, mineral and physicochemical analysis of T. catappa seed nuts. The proximate composition was determined according to the previous standard methods and elemental analysis by Atomic Absorption Spectrophotometry and Flame Photometer. Proximate composition revealed a moisture content of 02.34%, ash 03.89%, fibre content 08.50%, crude protein 29.66%, fat 21.98% and carbohydrate 33.63%. Elemental analysis of the plant have indicated the presence of iron, zinc, calcium, magnesium, potassium, sodium, copper and chromium in the aqueous extract. Physicochemical parameters of the plant revealed a specific gravity of 0.9182, viscosity 33.62 mm2/s, refractive index 1.4642, acid value of 0.102 mg KOH/g, saponification value of 151.28 mg KOH/g, iodine value 47.19 g I2/100 g and peroxide value 8.93 meq/kg. In conclusion, the findings from this study confirmed that almond nut oil has a long shelf life which may explain its applications in pharmaceutical, non-pharmaceutical and personal care industries.
Mediterranean journal of pharmacy and pharmaceutical sciences
For many decades, the lean concept has been praised for improving efficiency, maximizing productivity, and minimizing waste in manufacturing operations. Lean production is expected to create an industrial ecosystem that is more cost-efficient and accountable for optimizing resources and processes. However, in the context of lean manufacturing, new challenges have emerged as a result of the recent emphasis on sustainability. This study aims to show several criticisms of lean implementation and propose a holistic approach to achieve a more sustainable operation. The green-lean model, sustainable manufacturing, agile supply, and Lean 4.0, are approaches for integrating lean practices and sustainability. This will foster a culture of continuous improvement, employee empowerment, long-term collaboration with suppliers, added value for customers, and increased innovation in the economy.
In health care delivery systems, if you are not part of the solution, then you must be part of the problem. Over the last few decades, clinical pharmacy encourages pharmacists and pharmacy support staff to move their focus from product-oriented role towards new direct engagement with patients, to make the most of the benefits that patients obtain from the medicine they take, or the problems they encounter with their medicines use. In the USA, pharmacists’ participation in physicians ward rounds was shown to reduce adverse drug events by 78% and 66% in general medical and intensive care settings [1. 2]. A study covering 1 029 US hospitals indicated that centrally based and patient-specific clinical pharmacy services are associated with reduced mortality rates [3]. The services involved were medicine information, clinical research performed by pharmacists, active pharmacist participation in resuscitation teams and pharmacists undertaking admission medication histories. New pharmacists’ roles in healthcare systems around the globe have moved and developed significantly over the past few years, particularly with expansion of the scope of practice which allows pharmacists to focus on the clinical aspects of direct patient care [4, 5]. Pharmacists are drug therapy experts of health care team. Therefore, pharmacists, today, are the arbiters of effective and safe use of medicines. Medication therapy management is one of the major areas in which physicians more and more rely on pharmacists to benefit their patients.
Mediterranean journal of pharmacy and pharmaceutical sciences
Epilepsy is a chronic neurologic disease that comes third after cerebrovascular and Alzheimer’s disease. Anti-epileptic drugs may affect certain hematological parameters of epileptic patients. Few researches investigated hematological adverse effects of antiepileptic drugs in Libya. Thus, the aim was to evaluate hematological parameters in epileptic children who are on antiepileptic drugs. This retrospective study included 83 pediatric patients with epilepsy recruited from Benghazi Children Hospital, Department of Neurology, from December 2017 to April 2018. Data collected included demographic characteristics, types of epilepsy, anti-epileptic drugs and serum hematological parameters. Hematological parameters recorded included: hemoglobin, hematocrit, platelet, mean cell volume, mean cell hemoglobin, mean cell hemoglobin concentration and white blood cell count. In all treated patients, regardless of the number of antiepileptic drugs therapy used, the average levels of hematological parameters were significantly lower in treated group compared to control group (11.64 gm per dl, 34.53%, 27.74 pg and 33.13 gm per dl, respectively). A significant increase (12.12109 per l) in white blood cell counts in treated group was found. Average hemoglobin, hematocrit and mean cell hemoglobin concentration levels were significantly lower in patients on poly-therapy compared to mono-therapy and control groups. Average white blood cell counts were significantly increased in patients on anti-epileptic drugs. In sodium valproate users, levels of hematological parameters were significantly decreased but significantly increased in white blood cell counts. In diazepam users, significant increases in white blood cells and platelet but no difference in other parameters observed. There were no differences in all hematological parameters among patients using carbamazepine except for platelet counts (significantly decreased). In conclusion, there is substantial effect of the anti-epileptic drugs, especially sodium valproate, on hematological parameters of children despite the effects were not critical as the changes were still in the normal range.
Mediterranean journal of pharmacy and pharmaceutical sciences
Human being has lot of virtual mask in their behaviour (mind or brain). By the way of probability study alone, be able to find a person’s loyalty through their emotions, stress of speech, way of expressions and so on. It is not a novel technique to this world. The judgement and the hearings are finalizing in accordance to passed parameters (questions, transparent as well hidden test) and the result. Artificial Neural Network (ANN) is one of the best methods meant for speech stress analysing based cheap lie detection for the loyalty test. To show the results, polygraph is a comprehensible demonstration oriented approach. These methods are already used by the insurance fraud investigations and police. Through an individual’s stress (stress percentage or else range) voice as well their emotions are able to detect the loyalty. Lie detection techniques require being extremely confidential and dynamic. For the reason that voice stress analysis (VSA) parameters have to be an encrypted for avoiding speech practise with testing tool. Here this paper, outlooks by using for predicting the liars through Speech VSA.