Library automation is just not a book inventory where hold, issue and receiving of books by using technological tools and services. Our applied research was found that most of the library administrative functionalities such as ‘Acquisition and Accessioning’, ‘auto Indexing & Classification’ and auto Cataloging (Books & Non books materials)’, inventory with real-time OPAC facilities and many more library science concepts are still missing constructs in Universities/College libraries across the country. In this modern era the concept of eLibrary is more popular because availability and accessibility of digitized content sharing through IT/ICT infrastructure is huge. During our research we found that cognizance of Library automation was completely ignored and focused on only talking and establishment of eLibrary. As we all know that “Physical Library” is not a substitute for “eLibrary”. In fact eLibrary is part of a Physical Library to share authenticated digitized content through IT/ICT infrastructure. After a decade of our applied research in the area of Library science, eventually we recorded a lot of findings based on our survey and discussion with senior researchers and Librarians. Our serious and consistent effort makes to succeeds in designing comprehensively effective and efficient operational strategies to build a “world class Library Automation and Paper less Library Management System” for Universities/College libraries. This paper emphasizes about the comprehensive real-time architecture and operational modules and their effectiveness to achieve the user’s satisfaction (flow of functionalities as per the exact need of the Library Management system). This dealt with how emerging technological tools and services are effectively integrated for designing new strategies in the area of library science includes various automation process and security concepts (using Barcode/RFID). Eventually, our dream comes true in building Use of Emerging Technological Tools and Services to building world class Paper less Library Information &Management System [LIMS]. presently deployed and use of this software product in more than 300 satisfied and client locations in INDIA, this product popularly named as “eLib” by AarGees Business Solution, Hubli, India. Though, our research is still on and continuing for further development to build “Global knowledge sharing Centre”.
Industrial waste is one of the most essential sources of contamination in the surface environment. Among different industries, tannery industry releases huge amount of pollutants into the ecosystem. Long term disposal of the tannery wastes has resulted in wide contamination of agricultural land and water sources in different parts of India. An attempt was made to study the diversity status of different microbial organisms in tannery effluent treated samples in Dindugal, Tamil Nadu. It was found that Electrical Conductivity (EC) and heavy metal contents were higher and population density of different beneficial microbes found better. Among different microbes isolated, phosphate solubilizing microbes (PSB) was found maximum which is followed by fungi and actinomycetes. The population density of non-symbiotic and symbiotic nitrogen fixers were found to be low in numbers when compared to other samples screened. Similarly, occurrence and distribution of AM fungal spores were also found low in heavy metal polluted samples as compared to the samples collected from non-polluted outside tannery effluent treatment area. Among different Arbuscular Mycorrhizal (AM) fungi, Glomus species was found to be dominant in the samples collected from outside tannery effluent treatment area as compared to tannery effluent samples.
Ethnopharmacology is an information exchange and understanding about people's use of plants, fungi, animals, microorganisms and minerals to discover a a wealth of helpful therapeutic agents and explore their toxic potential passed On by oral tradition or in written documented form Materia medica. This study area provides a scientific backbone for developing active therapeutics based on the traditional medicine of various ethnic groups. It is the interdisciplinary scientific exploration of biologically active agents traditionally employed or observed by man. The broad spectrum Of this domain covers social (anthropology), chemical (chemistry), biological (botany, biochemistry, microbiology) and pharmaceutical sciences (pharmacognosy, pharmacology and clinical therapeutics). Many valuable drugs of today (e.g., atropine, ephedrine, tubocurarine, digoxin and reserpine) have been used by studying indigenous remedies. Chemists continue to use plant-derived drugs (e.g., morphine, taxol, physostigmine. quinidine and emetine) as prototypes in their attempts to develop more effective and less toxic medicines. Currently, USP and BP contain many active ingredients/excipients from natural sources. Its objectives include the preservation of indigenous medical knowledge to understand the pharmacological basis Of herbal medicine; scientific study of indigenous drugs to contribute in the long run to promote or improve primary health care in regions of study; search for pharmacologically unique principles from existing indigenous remedies; finding a valid reason to guard the rainforests or to engage in conservation; establish gene banks and libraries of plant extracts for future biological evaluation: well-established germplasm banks for essential crops. Ethnopharmacology can be an innovative and powerful discovery engine for newer, safer, and more affordable medicines from the treasure house (traditional knowledge of indigenous peoples) of ancient wisdom.
Before the start of the SARS-CoV-2 (COVID-19) pandemic, the whole environment around us had been deemed very toxic to breathe in due to the amount of greenhouse gases that had been emitted over the centuries. The Earth faced rising temperatures, which in turn led to the melting of glaciers and rising of sea levels. Environmental degradation was happening fast due to the depletion of resources such as air, water and soil. But after the coronavirus lockdown (Talabandi) commenced, there have been changes in the environment. The lockdown still has a huge impact on people in India too. The halt of industrial production and traffic resulted in cleaner air and rivers. In India the first phase of the nationwide lockdown that began on March 24 followed by enforcement of a series of regulations had some evidences that the COVID-19 curve is flattening in the country's COVID-19 affected regions. There was a good chance Prime Minister Narendra Modi extended the lockdown (Talabandi) four times that ended on (Phase 1 (24 March-14 April)., Phase 2 (15 April-3 May)., Phase 3 (4 May-17 May) & Phase 4 (18 May-31 May). The paper focuses on different aspects of environmental impact due to SARS-CoV-2 in India.
PFAPA syndrome (periodic fever, aphthous stomatitis, pharyngitis, and adenitis) is the most common periodic fever disorder in childhood, typically resolving by early adolescence. Relapse after a prolonged symptom-free interval is rare and has been reported following tonsillectomyrelated remission. We describe a 13-year-old girl with intact tonsils who experienced recurrence of PFAPA a decade after initial remission. She presented with a 6-day history of high-grade fever, aphthous ulcers, pharyngitis, and cervical adenitis unresponsive to antibiotics. Investigations showed elevated inflammatory markers, a negative infectious workup, and significant cervical lymphadenopathy on ultrasound. A single dose of prednisolone led to the rapid resolution of symptoms followed by sustained remission on follow-up. This case highlights the diagnostic challenges of late PFAPA relapse and underscores the importance of clinical recognition, exclusion of mimicking conditions, and corticosteroid responsiveness in guiding management.
Mobile pervasive environment interact with several devices at varying service ranges. The technical heterogeneity of pervasive environment is expected to increase the system flexibility and adaptability on modeling with context training phase. While working with context based training phase, time entity measure is considered as the significant issue. The evaluation of the services through numerous devices during training phase does not acquire an effective service monitoring on mobile pervasive environment. Mobile pervasive environment based information extraction fails to modify the patterns as activities change over time. To improve the flexibility of context training phase in mobile pervasive environment, an Active Context Source Discover Training Phase (ACSDTP) with Classifier Decision Tree Support (CDTS) mechanism is proposed in this paper. Our research work is to develop an effective modification (i.e., updation) of the pattern on training phase with real world context as per changes over time. Initially, the ACSDTP set up the available sensors in pervasive environment to work with the ever changing set of context users. The available sensors are maintained using the Active Discover process. Second, the CDTS mechanism is designed using weighted prediction for easy identification of context result on the training phase. Decision tree is operated separately using the learning techniques, where the identification is performed in a significant manner with minimal time factor. The learning process is performed to identify the inferred situations. Finally, the integration process is carried out to work with the complex association between the situations and sensor data in the mobile pervasive environment to achieve flexibility and adaptability factor. Experiment is conducted on factors such as time entity measure rate, precision ratio, and user context result determination level.
The current study was conducted to explore the antiemetic activity of ten aromatic medicinal plants viz., Carissa carandus L. (fruits), Chichorium intybus L (flowers), Cinnamum tamala L (leaves), Curcuma caesia Roxb (rhizomes), Lallemantia royleana Benth (leaves), Matricaria chamomila L (flowers), Piper longum L (fruits), Piper methysticum G. Forst (fruits), Piper nigrum Linn. (fruits) and Syzygium aromaticum (Linn.) Merr. & Perry (flowering buds) was studied using a chick emetic model. The ethanol extracts of these plants were administered at 150 mg/kg body weight orally. Domperidone was given at 100 mg/kg as a reference drug. All the extracts decrease in retches induced by copper sulphate pentahydrate given orally at 50 mg/kg body weight and showed comparable antiemetic activity with domperidone. Compound targeted antiemetic activity is further suggested. Aromatic plants have tendency to relief from nausea. Alpinea offinarum,Zingiber officinale, Mentha piperita, Menthaspicata and Lavandula angustifola,are aromatic plants reported to possess antiemetic activity. So, presentinvestigation was done to evaluate more aromatic plantsregarding their antiemetic activity. Results of the antiemeticactivity of the ethanol extracts of Carissa carandus,Chichorium intybus, Cinnamum tamala, Curcuma caesia,Lallemantia royleana, Matricaria chamomila, Piper longum, Piper methysticum, Piper nigrum and Syzygium aromaticum are shown in the Table. All the extracts showed antiemeticactivity comparable with domperidone. The % inhibition was recorded as Carissa carandus (68.29), Chichorium intybus (73.86), Curcuma caesia (89.97), Cinnamum tamala (70.64), Lallemantia royleana (83.61), Matricaria chamomila (59.92), Piper longum (81.65), Piper methysticum (80.03), Piper nigrum (89.48) and Syzygium aromaticum (87.81). The highest % inhibition was shown by Curcuma caesia (89.97) and the lowest by Matricaria chamomila (59.92), whereas domperidone showed 80.18 % inhibition of emesis.
The article is a discourse analysis of the Wildflower telerserye, exploring the themes and portrayals of the main character and the ambiguities projected by her characterization. The research’s objective revolves around the details that upon the attempt of the telersye to flaunt the modern archetypes of a Filipina, a strong and empowered woman who liberates under the yoke of patriarchal hegemony, her actions and ways were deemed crucial and subjected to great scrutiny. The researcher also dealt with how these portrayals affect and reflect the Filipinos’ way of thinking and sense of morality. Two major literary theories were used to underscore the article’s crucial points. To show how the woman portrayals in teleserye try to subvert the idea and configuration of patriarchy, Feminism (Helene Cixous) was used. Meanwhile, Deconstructionism (Jacques Derrida) was employed to show that in the attempt of the teleserye to empower the woman lead character, remove her from her marginalized and stereotypical views, and liberate her from the yoke of patriarchal hegemony, the result was otherwise. Based on these analyses, a synthesis of Filipinos’ sensibilities on how it affects and reflects their ways of thinking was crafted.
The most important factor that affects the crop production in terms of nutritional content of foliar plants is the global climate change. Herbivore’s growth, development, survival and geographical distribution all are determined by elevated CO2 and temperature. The interactions between herbivores and plants have changed due to increasing level of CO2 and temperature. The effect of high CO2 and temperature on grain legume plant which change in to plant physiology (e.g., nutritional content, foliage biomass) and how it change in herbivory metabolism rate and food consumption rate. Plant injury is determined by two factors viz. resistance and tolerance and both are influenced by greater CO2 and temperature. Legumes are an important source of food and feed in the form of proteins and also improve the soil environment. The repercussions of the abiotic factors mentioned above needs discussion among the scientific community. We may able to limit the negative repercussions of stated factors in future breeding projects by harnessing the practical favourable impacts and by including such influences of elevated CO2 and temperature on pulses productivity. The extensive research is necessary to overcome the negative effects of high CO2 and temperature on insect-plant interaction
Standardization of crude drugs is a code of conduct and an essential need of the time. Substitution and adulteration now become a widespread practice, which makes the global crude drug market unsafe for crude drugs depending on the world population. Moreover, crude drug evaluation is not easy because numerous influential factors affect the bio-efficacy and reproducibility of therapeutic effects. The broad spectrum of standardization ensures the correct substance in the proper amount for desired therapeutic effects. It also provides all possible careful measures taken from collection and manufacturing to drug dispensing for clinical application. The authors have tried to cover precise tools for crude drug standardization in the present review.
Background: Glaucoma is a group of disorders that can lead to irreversible vision loss if untreated. It affects individuals across all ages, genders, and ethnicities, with intraocular pressure (IOP) being the only modifiable risk factor. Regional studies highlight variations in the prevalence of glaucoma subtypes, underscoring the need for population-specific data to guide effective prevention and treatment efforts. This study aimed to explore the clinical characteristics and patterns of glaucoma patients in a tertiary care setting in Bangladesh. Methods: This was a hospital-based cross-sectional study, conducted from January to December 2023 at the Glaucoma Department of Deep Eye Care Foundation. A total of 2,172 individuals aged 20 years and above were conveniently selected as the study population. After explaining the study objectives, written informed consent was obtained from all participants. Ethical approval was obtained from the institutional review board of the Deep Eye Care Foundation. Data analysis was performed using the Statistical Package for Social Sciences (SPSS), with a P-value of less than 0.05 considered statistically significant. Results: The study population predominantly consisted of middle-aged and older adults, with a slightly higher proportion of females than males. Most participants were housewives, followed by farmers. A majority resided in rural areas rather than urban, and only a negligible number reported a family history of glaucoma. More than half of the patients presented with reduced visual acuity. The average IOP was nearly similar in both eyes. Most cases showed bilateral involvement of glaucoma. The predominant types of glaucoma were primary angle-closure suspects (PACS) and primary open-angle glaucoma (POAG). The main treatment approaches included beta-blockers and laser peripheral iridotomy, while a notable proportion of patients were kept under observation. Conclusions: Bilateral involvement and reduced visual acuity were common, with PACS and POAG being the predominant subtypes. This study offers unique insights into the demographic and clinical profile of glaucoma in rural communities, emphasizing the need for communitybased screening, gender-sensitive eye care, and early detection to reduce visual disability.
Whitefly, Bemisia tabaci (Genn.) and yellow mosaic virus disease incidence in mungbean, Vigna radiata (L.) Wilczek is a most serious problem in northern states of India. Bioefficacy of some insecticides and biorational were tested during kharif 2010 to 2011 and 2011 to 2012 at Pulses Research Farm, Department of Genetics and Plant Breeding, CCS Haryana Agricultural University, Hisar. The results revealed that 30 days after sowing minimum whitefly population was recorded in plots, when seeds were treated with dimethoate 5 ml/kg seeds. At three days after spray application lowest whitefly population (1.6 and 6.4 adults/ cage/ plant) was noted in NSKE 5 per cent sprayed plots. At seven days after spray, NSKE 5 per cent and triazophos 0.04% was the most effective in keeping the whitefly incidence and yellow mosaic virus infection low. Triazophos and NSKE did not help in managing the whitefly population at low level up to 10 days after spray application. Spraying of triazophos 0.04% resulted in higher grain yield as well as net profit. Lower dosage of triazophos 40EC at 0.02% enhanced the whitefly population in 2011 to 2012. However, the maximum incremental cost benefit ratio (1:13.41) was obtained in dimethoate 5 ml/kg seed treated plots followed by seed treatment with dimethoate plus spraying of triazophos 0.04% (1:11.93).
Oxidative stress is due to altered levels of prooxidants and anti-oxidants in the body. This can lead to tissue damage especially the central nervous system. Oxidative damage has been implicated in several disorders including some psychiatric disorders such as schizophrenia and major depressive disorder. Uric acid is an anti-oxidant which prevents tissue damage caused by oxidative stress. In this review, the reduced levels of serum uric acid in schizophrenia and depression are discussed. The effect of treatment in these disorders leading to increased serum uric acid levels are also reviewed.
Mediterranean journal of pharmacy and pharmaceutical sciences
Regression modeling analyses the relationship between two or more variables and can be used to predict the response variable from one or more independent variables. The present study uses linear regression analysis to evaluate the growth in the two fish species of genus Oreochromis, Nile tilapia and Jipe tilapia, under aquaculture conditions. The models were fitted using a collection of functions in the R-software library. The final models were selected using the goodness of fit criteria based on the coefficient of differentiation, the model p- values and Akaike information criteria. The significance of the linear relationship between predictor variables and the mean response was tested by comparing the computed standardized parameter estimates, whereas the confidence intervals were constructed to assess the uncertainty of predicting the response variable and determine outliers in the model. Generally, both species exhibited good condition during growth and all the measured water quality variables significantly afffected growth (p<0.05). However, only temperature and dissolved oxygen produced the most important linear relationship with fish weight. The study recommends that data from a controlled experiment should be used the determine the interactions between the two growth variables.
Abstract In every hospital, Casualty department deals with the emergency cases. These emergency cases also includes medicolegal cases like road traffic accidents, Poisoning, assaults are dealt in the casualty and detailed MLC report is made here after giving the proper primary treatment and life saving measures. The police is informed about MLC as early as possible. Important preventive measures like drawing public attention and awareness towards traumatic casualties can help in the prevention or management of unnatural (medicolegal cases). Considering the importance of above points, a one year retrospective study from 1st March 2018 to 31st March 2019 was conducted in the Casualty department of Tertiary Care Centre.
India’s economic system has undergone significant changes in recent years reflecting globalization and changes in national policies. This paper provides a comprehensive analysis of India’s economic growth, focusing on imports and exports. The study explores the key drivers of economic expansion, including trade liberalization, trade agreements, and technological advancement. It also explores the impact of international trade and geopolitical events on business models. It assesses the role of policy measures such as the Goods and Services Tax (GST), the Make in India initiative, and various free trade agreements in generating economic benefits. The paper also assesses the trade balance and its impact on India’s economic stability and growth. The paper concludes with recommendations for improving the market, including diversifying entrepreneurs, investing in infrastructure, and strengthening the domestic economy. The review provides insights to policymakers, businesses, and academics who want to understand and harness India’s economic potential in the global economy.
Vitamin E is extensively available in the natural world and is produced by prototrophs such as plants, algae, and blue-green algae. Vitamin E is used as a dietary supplement, an antioxidant food stabilizer, a pharmaceutical additive, and a preservative in livestock feed. Several types of vitamin E can be differentiated by the position and number of the methyl functional group, and each form has a unique biological role. The function of antioxidants such as vitamin E is to defend cells from the effects of oxidative stress. Vitamin E is a free radical scavenger converted to vitamin E radical, then converted back to vitamin E by ascorbic acid. Vitamin E was discovered by Evans and Bishop in 1922; it has proved to be an effective nutrient for reproduction. It is also possible for vitamin E to act by a mechanism not directly linked to the inhibition of oxidation. Such non-antioxidant actions of vitamin E may result from gene regulation and specific cell signalling. The function of vitamin E in cellular signalling, especially its biological impact, is undoubtedly an imperative subject for future studies. The explicit roles of the several isomers and esters of vitamin E analogues should also be the subjects of future studies.
This study investigated the management of teachers’ soft skills development and flexible learning environment as a correlate of teachers’ effectiveness in Unity schools in South- Eastern states of Nigeria. The correlational research design was adopted for the study. Two research questions were answered while two hypotheses were tested. The population of the study comprised all the 901 teachers of the 14 Unity schools in the 5 South-Eastern states of Nigeria. Stratified and disproportionate sampling techniques were used to select 399 sample size that was determined from the population using the Taro Yamane formula. Two sets of instruments titled; “Management of Seamless Technology Integration Questionnaire” and “Teachers’ Effectiveness Questionnaire” were used for data collection. Face and content validity was ensured by five experts including the researcher’s supervisors. The reliability coefficients of the two instruments were calculated to be 0.79 and 0.81 using Cronbach Alpha method. Multiple and simple regressions were used to answer the research questions. Analysis of variance associated with multiple regression and t-test associated with simple regression was used to test the null hypotheses at 0.05 alpha level. It was found that management of teachers’ soft skills development and flexible learning environment positively correlate (0.92 and 0.86 respectively) to teachers’ effectiveness in Unity schools in the South-Eastern states of Nigeria. Based on the findings, it was concluded that the management of seamless technology integration is positively and highly significant to teachers’ effectiveness in Unity schools in the South-Eastern states of Nigeria. It was therefore recommended among others that school administrators in the 14 Unity schools in the South-Eastern states should immediately embark on self-development in the management of seamless technology integration
Introduction: Psilocybin mushroom use is well documented in spiritual and religious ceremonies globally. This drug is now the most popular in Europe and the USA. Objective: The objective of this study is to explore the experiences and effects of psilocybin on patients with depression and anxiety. Method: A qualitative study was conducted interviewing ten participants currently taking psilocybin while experiencing depression and/or anxiety. Ethical approval was obtained from the University ethics committee. Participants were recruited via social media and groups are known to have used psilocybin for the treatment of anxiety and/or depression. Participants were informed of study aims and consent was obtained before interviews commenced. Confidentiality was maintained throughout this study. Interviews began with informing participants that psilocybin may be effective in the management of depression. Initially, information around the way treatment with psilocybin was obtained was sought. This was followed by queries around the effects of the drug in terms of experiences both during and after treatment. Finally, participants were asked to outline the positive effects of psilocybin on their lives. Results: The data were thematically coded using Grounded Theory as an underpinning philosophical paradigm. Emerging themes included enhancement of smell, vision, hearing, and taste sensations. Another theme emerging was the experience of being ‘connected with the universe’ while on the drug. Additionally, participants reported a stabilization of mood, an increase in optimism and emotional control, and a healthier emotional connection with others. Most also felt an increase in comfort, peace and calmness. Another theme that emerged centered on the mechanism of action of psilocybin. Participants stated that this substance seemed to ‘make new connections in their brain,’ resulting in new perspectives. Some participants felt this resulted in a calming influence on the mind and body. This aligns with research showing that psilocybin works by changing the thinking and improving information processing. Conclusion: Psilocybin has promising effects on the patients with depression/anxiety even after a single dose. Psilocybin is safe but the administration should be guided by a health professional to yield safe and positive outcomes.
The contribution of financial perspective measures to improving organizational performance is empirically examined in this article. The study examines how financial metrics like ROI, cost control, profitability, and revenue growth relate to organizational effectiveness using the case of MTN Ghana. It is based on the balanced scorecard framework. The study uses a quantitative approach to investigate the relationship between financial performance metrics and important success indicators like market share, operational effectiveness, and shareholder value, using data from a dataset of different companies in multiple industries. The results of the study show how important financial perspective metrics are for reaching competitive advantage and sustainable growth. Businesses that put a high priority on strategic fiscal management typically perform better, especially when it comes to cost-effectiveness, liquidity, and profit margins. But the study also highlights the drawbacks of depending only on financial indicators. To create a more thorough performance evaluation system, it emphasizes the need to combine financial measurements with non-financial indicators like employee development, internal processes, and customer satisfaction. In summary, the study offers practitioners and scholars useful information by offering evidence-based recommendations for enhancing financial strategies. Organizations can develop a balanced approach to performance measurement that promotes long-term success by using both financial and non-financial metrics. The article ends with practical suggestions for businesses looking to increase output and streamline their budgets.