Biomedicine & Pharmacotherapy

pISSN : 0753-3322

Publisher : Elsevier BV

Website : clinicalkey.fr

Natural products targeting the atr-chk1 signaling pathway in cancer therapy

Cancer is one of the most severe medical conditions in the world, causing millions of deaths each year. Chemotherapy and radiotherapy are critical treatment approaches, but both have numerous adverse health effects. Furthermore, the resistance of cancerous cells to anticancer medication leads to treatment failure. The rising burden of cancer more...


Marine peptides in breast cancer: therapeutic and mechanistic understanding

Breast cancer is the most prevalent invasive form of cancer in females and poses a significant challenge to overcoming the disease burden. The growth in global cancer deaths mandates the discovery of new efficacious natural anti-tumor treatments. In this regard, aquatic species offer a rich supply of possible drugs. more...


The mechanistic insight of polyphenols in calcium oxalate urolithiasis mitigation

About 12% of the world's population is affected by different forms of urolithiasis, of which the recurrence rate in females is 47–60% and in males is 70–80%. Standard therapeutic agents (allopurinol, citrate, cystone and thiazide diuretics) prevent and treat urolithiasis. Still, these are not universally-effective due more...