Isrn Cell Biology

eISSN : 2090-7389

Publisher : Hindawi Limited

Autophagy mechanism, regulation, functions, and disorders

Autophagy is a self-digesting mechanism responsible for removal of damaged organelles, malformed proteins during biosynthesis, and nonfunctional long-lived proteins by lysosome. Autophagy has been divided into three general types depending on the mechanism by which intracellular materials are delivered into lysosome for degradation that is, microautophagy, chaperone-mediated more...