Universal Journal Of Pharmaceutical Research

pISSN : 2831-5235

Publisher : Society of Pharmaceutical Tecnocrats

A systems based approach to microbiological quality assessment in a healthcare facility’s water distribution network: a case study

Background: Water distribution systems within healthcare facilities are complex ecosystems that can harbor opportunistic pathogens, posing a significant risk to patient safety. Ensuring the microbiological quality of water requires rigorous monitoring and a deep understanding of the entire system, from source to point-of-use. This study undertakes a comprehensive more...


Environmental monitoring performance analysis: a comparative study of class c and class d controlled environments

Monitoring and controlling of clean area environment is of paramount importance to ensure product safety and quality. This comprehensive analysis evaluates environmental monitoring (EM) data from Class C and Class D controlled environments in pharmaceutical manufacturing, utilizing Active Air (AA), Passive Air (PA), and Contact Plate (CP) or Replicate Organism more...


A non-parametric framework for analyzing spatial heterogeneity and contamination pathways in healthcare environments

Background:The systematic management of microbial bioburden in Class C healthcare cleanrooms is a critical factor in patient safety. Standard environmental monitoring often overlooks the complex spatial and statistical relationships of contamination. This study applies a rigorous statistical framework to a comprehensive environmental monitoring dataset to accurately map contamination risk. more...


Slu-pp-332 and related errα agonists: a focused minireview of metabolic regulation, and therapeutic potential

The global burden of metabolic disorders, including obesity and type 2 diabetes, necessitates innovative therapeutic strategies. SLU-PP-332, a synthetic agonist of estrogen-related receptor α (ERRα), has emerged as a promising exercise mimetic, demonstrating preclinical efficacy in enhancing mitochondrial biogenesis, insulin sensitivity, and energy expenditure. This brief review synthesizes more...


Intergenerational epigenetic inheritance: a minireview of mechanisms and implications for human health and disease

The concept of inherited memories, where experiences from one generation can influence the traits and behaviors of subsequent generations, has long captivated scientific curiosity. Recent advancements in epigenetics have provided compelling evidence for the potential mechanisms underlying this phenomenon. This focused brief review article outlines the current state of knowledge more...