Evaluation of diabetes mellitus type 2 effects on kidney function

Type 2 Diabetes mellitus contributes to the development or progression of many chronic and age-related pathological processes. One of the major risk factors for morbidity and mortality among patients with diabetes is renal and vascular disease as well as heart disease. Type 2 diabetes mellitus was associated with a significantly increased age of kidney disease with higher urea and creatinine levels. 76 Libyan subjects participated in the study. The subjects were divided into three categories. One group hosts diabetes case (n=40) while the other group serves as a control (n=12) and the other group has no type 2 diabetes mellitus but urea and creatinine levels are elevated (n=36). After oral informed consent of the study participants, 5 ml of venous blood was drawn under sterile conditions for whole blood analysis. Fasting blood sugar was analyzed. Urea and creatinine levels were compared between diabetic and non-diabetic patients. However, a statistical analysis was performed using IBM SPSS version 26 where the correlation between parameters was analyzed by an independent samples t-test. In this study, patients with type 2 diabetes mellitus caused a significant increase in urea and creatinine compared to the control group. The study indicated that type 2 diabetes mellitus increases the damage to the kidney function.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

Satiating a user-delineated time constraints while scheduling workflow in cloud environments

Cloud computing is used to achieve sustainability in terms of computing. It reduces energy and resource consumption. Most of the companies have been moving their applications to the cloud to reduce power, energy re-source, and carbon emission. Today's computing landscape is rapidly shifting toward creating applications to leverage Cloud platforms to have necessary features such as elasticity, virtualization, low cost, and pay-per-use. Cloud computing's rising demand and versatility are achieving acceptance in the research community as a means of implementing large-scale electronic systems in the format of workflows (set of tasks). One of the most important objectives of this effort is to trim down makespan which is the total period taken by the resources to complete all workflow activities. Another foremost objective of this work is to satiate all the user-delineated time constraints while scheduling workflow activities.

Mohd haroon

"potential antidiabetic activity of m. charantia linn. extract on alloxan induced albino wistar rats in diabetes mellitus: an in vivo approach".

The study of diabetes is not only limited to particular symptoms, but it is consequently affects the pathological and functional changes in the metabolic pathways of human body system. In those symptomatic diseases various drugs are used to treat the diabetes such as biosimilar therapy including use of insulin and insulin analogues, oral hypoglycaemic agents and various other complementary medicines. In understanding of suggested potential antidiabetic, effect of M. charaantia Linn. on fasting blood sugar levels and its biochemical analysis in alloxan- induced diabetic rats were investigated. The extracts of M. charaantia Linn. Produced a significant antidiabetic activity at normal dose levels of their lethal doses. A comparison between the action of reduction in blood glucose level in different dose forms of M. charantia extract and Std. drug were seen. An oral glucose tolerance or oral tolerance test were performed with the use of glucose strip Accu-check meter. The different extract viz. ethanol extract + water, petroleum ether + Isopropyl alcohol extract were used for further dosing purpose. The ethanol + water extract were showed significant (P<0.001) antidiabetic activity. In alloxan induced rat model blood glucose level were as, 214.5±5 mg/dLfor std.drug and 216.5±5 mg/dL in comparison with diabetic control 225.5±5 mg/dL. An ANOVA was used for the statistical analysis and p-values less than 0.01 compared to normal group and 0.05 compared to diabetic control group were considered statistically significant. The extract of M.charantia Linn. from seed at the dose of 250 mg/kg, significantly shows the better result in reduction of blood glucose level as compared to the concentration of 500 mg/kg. The increased level of glucose due to the damage of pancreas showed regeneration of pancreatic enzymes by extract of M. charaantia Linn. Which were damaged by alloxan treatment. These solvent extract also balance the body weight loss in diabetic rat, hence the present extract shows the potential to act as antidiabetic drug.

Dr. Wahul Umesh B Dr. wahul umesh b

Models of data structures in educational visualizations for supporting teaching and learning algorithms and computer programming

Teaching and learning computer programming is challenging for many undergraduate first-year computer science students. During introductory programming courses, novice programmers need to learn some basic algorithms, gain algorithmic thinking, improve their logical and problem-solving thinking skills, and learn data types, data structures, and the syntax of the chosen programming language. In literature, we can find various methods of teaching programming that can motivate students and reduce students’ cognitive load during the learning process of computer programming, e.g., using robotic kits, microcontrollers, microworld environments, virtual worlds, serious games, interactive animations, and visualizations. In this paper, we focus mainly on algorithm visualizations, especially on the different models of data structures that can be effectively used in educational visualizations. First, we show how a vector (one-dimensional array), a matrix (two-dimensional array), a singly linked list, and a graph can be represented by various models. Next, we also demonstrate some examples of interactive educational algorithm animations for teaching and learning elementary algorithms and some sorting algorithms, e.g., swapping two variables, summing elements of the array, mirroring the array, searching the minimum or maximum of the array, searching the index of minimum or maximum of the array, sorting elements of the array using simple exchange sort, bubblesort, insertion sort, minsort, maxsort, quicksort, or mergesort. Finally, in the last part of the paper, we summarize our experiences in teaching algorithmization and computer programming using algorithm animations and visualizations and draw some conclusions.

Ladislav Végh Ladislav végh

Selection of potential isolates of plant growth promoting rhizobacteria (pgpr) in conferring salt tolerance under in vitro

Salinity is a major environmental stress which has been studied extensively and has its impact on agriculture in the past, present and future. The global importance of salt affected soils can be explained by their wide distribution on all continents covering about 10% of the total land surface. At present, there are nearly 954 million ha of saline soils on earth’s surface. It is extremely difficult to quantify the social and economic costs of salt prone land and water resources. Plant Growth Promoting Rhizobacteria (PGPR) is a group of bacteria that actively colonize plant roots and increase plant growth and yield. They play an important role within the interaction between soil and plant. As plants grow on marginal soils such as saline soils, the importance of the rhizobacteria increases as they mobilize nutrients and provide tolerance ability to the plants. In the present study, an attempt was made and isolated 51 PGPR isolates (Phosphate Solubilizing Bacteria–18; Azotobacter spp.-16 and Azospirillum spp.-17) from different salt affected areas in Tamil Nadu and Puducherry. All the isolates were screened for their efficacy against different sodium salts namely sodium chloride, sodium citrate and sodium sulphate. It was observed that the absorbance of the culture broth grown in salt stress to sodium chloride decreased with increasing concentration of the salt. Similarly decrease in growth pattern in terms of the absorbance was also observed in salt stress to sodium citrate and sodium sulphate.

Dr. SARANYA DEVI K Dr. saranya devi k

A study to assess coping strategies adopted by adolescents studying in selected schools of distt. mohali, punjab.

The study was conducted by researcher on Coping strategies adopted among adolescents in selected Schools, Distt. Mohali, Punjab. The main aim of this study was to assess on Coping strategies adopted among adolescents, to find out the association between coping strategies adopted among adolescents with their selected socio demographic variables.Descriptive Research design has been used to assess the Coping strategies among 400 adolescents studying in Golden Bell’s school,Sector-77 and Shemrock School, sector 69, in Distt Mohali,Punjab. The sample was selected by Systematic random sampling technique. Pilot study was conducted on 10% of population and sample consists of 40 adolescents. Data on Coping Strategies adopted among adolescents were collected under two sections, Section A- Socio demographic variables and Section B- Coping Strategies Scale of Prof. A.K. Srivastava to assess coping strategies adopted among adolescents. Data was analyzed through Descriptive and inferential statistical methods. The results showed that majority of adolescents were adopting moderate Coping Strategies.There was significant association between Coping Strategies adopted by adolescents with their selected demographic variable such as Class of study, Occupational Status of Mother and Monthly Family Income.Based on the findings of the study, recommendations were drawn on nursing service, nursing education, nursing administration and nursing research.

Anu sharma Anu sharma

Analysis of edaphic factors in few villages of mysuru district

Analysis of Edaphic Factors in Few Villages of Mysuru District

Veerabhadraswamy AL Veerabhadraswamy al

Dosing in the neonatal intensive care unit

Over the years, pharmacy has developed from a simple floor stock system to a complex unit dose, I.V. additive, and clinical pharmacy program. This development would have never been possible without the support of the nursing, medical, and administrative staff. The support of obtained slowly by developing services that increase the pharmacist's credibility as a team member concerned with the pediatric and neonate patients. These services include a unit dose program, I.V. additive program, drug information services, and pharmacy medication program. One area in which pharmacist does not obtain a background from generalized training is the area of pediatric dosing. Pediatric pharmacists must learn in clinical practice the proper dosing of the pediatric patient and neonate patient. The dose must be checked periodically. In the premature or newborn infant, the pharmacist must consider the immature renal and hepatic function so that he/she does not overdose initially and then underdose as the infant grows and matures. Neonates are a special group of children, they are less than 30 days, and within this group preterm babies (that means less than 37 weeks). Determining the correct dose for drugs used to treat neonates is a critically vital factor. Prematurity affects kidney and liver function and the proper adjustment of drug doses is crucial [1]. The absence of drug level necessitates the adjustment of drug doses and the presence of qualified oriented dependable pharmacists. Drug doses are not numbers, or decimals used within the therapeutic range. Neonatal Intensive Care Unit (NICU) needs a system for the calculation and preparation of drugs [2].

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

Exploring globally used antiurolithiatic plants of m to r families: including myrtaceae, phyllanthaceae, piperaceae,polygonaceae, rubiaceae and rutaceae

Urolithiasis is a common worldwide problem with high recurrence. This review covers thirty-six (36) families starting from alphabet M to R. It includes Rubiaceae (17); Phyllanthaceae and Rutaceae (09); Polygonaceae (08); Pinaceae and Piperaceae (06); Menispermaceae, Myrtaceae, Oleaceae, Oxalidaceae, Plantaginaceae and Ranunculaceae (05); Moraceae and Musaceae (04); Meliaceae, Orchidaceae and Rhamnaceae (03); Moringaceae, Onagraceae, Papaveraceae, Pedaliaceae, and Polygalaceae (02); Magnoliaceae, Malpighiaceae, Molluginaceae, Myoporaceae, Nyctaginaceae, Paeoniaceae, Parmeliaceae, Parnassiaceae, Periplocaceae, Platanaceae, Polypodiaceae, Portulacaceae, Primulaceae and Punicaceae (01) plant used globally in different countries. Hopefully, this review will be helpful for the general public and attract the scientific world for antiurolithiatic drug discovery.

Dr. Salman Ahmed Dr. salman ahmed

Impact of foreign universities on indian higher education

The planned opening of foreign universities will foster cultural exchange, expose Indian students to diverse perspectives and promote international understanding, according to Gedam Kamalakar. Foreign university campuses have the potential to attract foreign investment, create job opportunities and stimulate the local economy through increased spending on infrastructure, accommodation and services. Partnerships with foreign universities on joint research projects will enhance knowledge exchange and technological advancements. Nevertheless, the influx of foreign universities can pose a threat to domestic educational institutions by alienating talented students and faculty and exacerbating inequalities in access to quality education. There is hence a danger of cultural imperialism. Indigenous knowledge and traditions may be marginalised due to the dominance of Western educational systems and values. Increasing opportunities to study abroad may also increase brain drain.

Dr Gedam Kamalakar Dr gedam kamalakar

Indian advertising demand in terms of cultural society

Simply put, advertising is an important marketing strategy that works in conjunction with information and persuasion channels. Every single person is exposed to commercials on a daily basis. They've become an inseparable part of the print medium, whether it's newspapers or magazines, over time. This is also true in the case of broadcast media, where ad-commercials predominate. The Indian advertising industry has grown tremendously from a small business to a full-fledged industry. The purpose of this study is to determine the advertising attractions and the influence they have on Indian culture. Advertisements in India are not only used to sell products. It sells dreams, visions, and the ideal way of life, while also reinforcing stereotyped values. The longer an individual is exposed to an advertisement, the more likely it is that it will effect them. The appeals' goal is to change how people think about themselves and how they decide whether or not to buy certain things will benefit them. Because India has such a large population and cultural diversity, the advertising industry has created a wide range of advertisements to capture people's attention and persuade them to buy products. The appeals are written in such a way that they have an impact on people's purchasing decisions.

Dr. Amarjeet Singh Dr. amarjeet singh

Preparation and characterization and biodistribution studies of lomustine loaded plga nanoparticles by interfacial deposition method

The incorporation of lomustine, a hydrophobic anticancer drug into PLGA nanoparticles by interfacial deposition method was optimized. Based on the optimal parameters, it was found that lomustine-PLGA nanoparticles with acceptable properties could be obtained. Optimization of formulation variables to control the size and drug entrapment efficiency of the prepared nanoparticles seems to be based on the same scientific principles as drug-loaded nanoparticles prepared by nanoprecipitation, solvent evaporation method. The process was the most important factor to control the particle size, while both the drug-polymer interaction and the partition of drug in organic and aqueous phases were the crucial factors to govern the drug entrapment efficiency. PLGA concentration at lower level (100 mg), 1:5 organic phase: aqueous ratio, 1%w/v PVA concentration, 3%w/v pluronic F68 achieved smaller particle size. Additionally, L:G ratio of PLGA 75:25, lower volume of organic solvent (1:10 organic phase: aqueous phase), higher initial drug content (10mg) enhanced the drug entrapment efficiency and maintained lomustine concentration in blood for an extended time period, elevated lomustine concentration in lungs and slowed the elimination of lomustine. The biodistribution profiles of prepared nanoparticles in albino mice showed higher plasma drug concentration for longer period of time, elevated drug concentration in lungs and slow elimination from kidney. No toxic effects of prepared nanoparticles were observed in histopathological examination of lungs and kidney. The systematic investigation reported here promises the development of PLGA nanoparticles loaded with lomustine when tested in Lung Cancer cell line L132 and toxicological/ histopathological studies in albino mice.

Archana Mehrotra Archana mehrotra

Natural and anthropogenic changes threatening the ecological and limnological integrity of lake baringo, kenya: a review

Lakes are characterized by dynamic responses to ecological and limnologic disturbances that occur within a constrained timeframe. Some endorheic lakes in the Kenyan Rift valley are presently regarded as environmental hotspots because of complex changes that are revealed through multiple proxies; changing lake levels and surface area, turbidity and sedimentation, and the proliferation of macrophytes, and loss of aquatic biodiversity. Lake Baringo is characterized by widespread catchment degradation accompanied by high levels of turbidity during erratic and decline of the native fishery based on Oreochromis niloticus baringoensis. A careful analysis implicates potential natural factors such as catchment topography and increasing anthropogenic pressure as the main causes of lake ecosystem degradation. This paper recommends several strategies for restoration of Lake Baringo based on an integrated multi-faceted approach that combines catchment rehabilitation, pollution control, and provision of alternative livelihoods such as agriculture to the riparian communities

Omweno job Omweno job

A review on globally used antiurolithiatic monoherbal formulations belonging to boraginaceae, brassicaceae, malvaceae and poaceae families

Urolithiasis is a common worldwide problem with high recurrence. This review covers thirteen (13) antiurolithiatic plants of the family Boraginaceae, twenty (20) from Brassicaceae, twenty-three (23) from Malvaceae and twenty-four (24) from Poaceae used globally in different countries. Hopefully, this review will be helpful for the general public and attract the scientific world for antiurolithiatic drug discovery.

Dr. Salman Ahmed Dr. salman ahmed

Small business management and financial literacy for young entrepreneurs

Youth entrepreneurship contributes to the social, cultural, and economic development of society, especially in many developing countries. The idea of encouraging young people to start businesses for a variety of reasons is now widely encouraged. However, there are many challenges and doubts faced in starting a business particularly after the Covid-19 is over. Therefore, the community service was carried out by lecturers at Business School, Universitas Pelita Harapan Medan Campus, providing the onsite seminar and training to 70 high school students at Santo Nicholas School in February 2023. The purpose of the community service was to encourage the students to plan their business projects by presenting data and information on the latest trends and issues in entrepreneurship and finance, as well as conducting one-to-one sessions with the students. Most of the students were enthusiastic throughout the activities resulting in several business plans and proposals being created at the end of the community service. It is implied that young people are indeed motivated to begin their entrepreneurship journey and school is the right place for them to acquire the necessary knowledge and skills. Teachers and parents are suggested to continue to assist the students by providing the commitment and funding required to begin and sustain the business.

L L

Review on non-destructive testing of composite materials in aircraft applications

The increasing usage of composite materials has immersed simpler techniques for inspecting the integrity of composite structures, as composite materials typically have probability of getting material imperfections. In non-destructive testing, shearography reveals defects in associate object by distinguishing defect-induced deformation anomalies. Non-destructive testing (NDT) methods skit and streamer role in physical characterization of new composite materials and in assessment of their quality and serviceability in structures. Non-destructive testing (NDT), Non-destructive inspection (NDI), and Non-destructive evaluation (NDE) are concerned with the techniques and measurements that provide data on the condition of the materials and structures at the time of manufacturing and in-service.

Boopathy Govindarajan Boopathy govindarajan

Innovation in research in undergraduate in india

This brief inspects the situation with research in Indian advanced education and offers an outline of the idea of undergrad (UG) research as a method for change. The article endeavors a short survey of the public authority endeavors to further develop advanced education examination, and underlines the restrictions of their degree just as their ramifications. Through a sweeping audit of existing experimental and subjective investigations, this concise shows the advantages and effects of UG research on improvement of insightful characteristics in understudies also its impact on foundations. At last, it suggests methods of drafting this idea in the current arrangement of undergrad schooling in India, in view of remedies by the Chamber on Undergrad Exploration

Dr Gedam Kamalakar Dr gedam kamalakar

Prevalence of dyslipidemia among persons with type 2 diabetes in africa: a systematic review and meta-analysis

Background: Dyslipidemia is an established cardiovascular risk factor in persons with type 2 diabetes (T2D), yet the extent to which these conditions co-occur in Africa is unknown. This systematic review and meta-analysis aimed to determine the prevalence of dyslipidemia among persons with T2D in Africa. Methods: Medline, Embase, Global Health, Scopus, and Web of Science were searched on 5 December 2023. This review adhered to the PRISMA guidelines and was prospectively registered on PROSPERO. The prevalence data for dyslipidemia was pooled through a random-effects meta-analysis. The authors assessed heterogeneity and publication bias using I2 statistics and Egger’s test, respectively. Results: Our search identified 8035 records, of which 60 articles involving 20 034 individuals with T2D were included in this review. The pooled prevalence of dyslipidemia recorded 38.6% (95% CI: 34.1–43.4) for high TC (≥ 5.2 mmol/l), 52.7% (95% CI: 44.2–61.1) for high low-density lipoprotein cholesterol (LDL-C) (≥ 2.6 mmol/l), 43.5% (95% CI: 37.1–50.0) for low high-density lipoprotein cholesterol (HDL-C) (< 1.0 mmol/l in men and less than 1.3 mmol/l in women), and 37.4% (95% CI: 32.2–42.9) for high triglycerides (TG) (≥ 1.7 mmol/l). Subgroup analysis based on gender indicated a notably higher prevalence of dyslipidemia among females compared to males. Conclusion: Dyslipidemia is prevalent among persons with T2D in Africa. This highlights the need for early screening, diagnosis, and management of dyslipidemia to mitigate the risk of cardiovascular complications in this population.

Emmanuel Ekpor Emmanuel ekpor

Biodiversity census and its significance in india: a scrutiny

Conservation of Biodiversity is an activity must carry out by all individuals in the world to share the benefits derived from biodiversity. It is a critical task to conduct the biodiversity census and conservation (Biodiversity C & C or Biodiversity C2). Throughout the world several Governament and Non-Governamental organizations work together as a unit to maintain our biodiversity in safe mode. India is a mega diverse country with rich biodiversity. The development of modern science and technologies have increased the value of biodiversity and associated traditional knowledge. To save valuable biodiversity and traditional knowledge of our country, National biodiversity board and State biodiversity board constantly involved in this approach and biodiversity law's support to conserve the living diversity.

Veerabhadraswamy AL Veerabhadraswamy al

A study of special educators‟ knowledge of therapies"

Therapies highly plays a crucial role for all those children and adults with disabilities. In this article, We aim to research the Special Educators’ Knowledge about Therapies in various special schools in the city of Hyderabad, Telangana, India. A qualitative approach was taken for this purpose. Questionnaires was used to collect the data. It was found that the teachers did not have proper conception on Therapies. The data indicated that the teachers are unaware about the unconventional therapies such as Drama Therapy, Pet Therapy and Laughter Therapy and there benefits when working with CSN. This lack of awareness needs to be addressed for the enhancement of the teacher as well students capabilities.

Husna habib Husna habib

‹ First  < 4 5 6 7 8 >  Last ›