India is a diverse land with a population of approximately 1.3 billion,1 placing India at the second position in the world in terms of population. Among these, Seventh-day Adventists' existence, as per the statistics of 2019, is 1.14 million.2 India is a richly diverse community, inclosing a diverse range of ethnic groups, each, not just different, but on occasion quite the opposite. The present population of the country can be divided among four racial groups: Negritos, proto-Australoid, the Mongoloids, and the Mediterranean.34 These racial groups today majorly fall in different ethnic groups based on their linguistic classifications. They are Indo-Aryan (78.05 percent), Dravidian (19.64 percent), and the remaining 2.31 percent of the population segregated among Austroasiatic (Mon-Khmer), Sino-Tibetan, and Tai-Kadai.5 This ethnic diversity can be easily seen within the Adventist church too.
In the last decade, we have observed the usage of artificial intelligence algorithms and machine learning models in industry, education, healthcare, entertainment, and several other areas. In this paper, we focus on using machine learning algorithms in the loan approval process of financial institutions. First, we briefly review some prior research papers that dealt with loan approval predictions using machine learning models. Next, we analyze the loan approval prediction dataset we downloaded from Kaggle, which was used in this paper to compare several machine learning classification models. During this analysis, we observed that credit scores and loan terms are the attributes that probably most affect the result. Next, we divided the dataset into a training set (80%) and a test set (20%). We trained 27 various machine learning models in MATLAB. Three models were optimized with Bayesian optimization to find the best hyperparameters with minimum error. We used 5-fold cross-validation for the validations to prevent overfitting during the training. In the following step, we used the test set on trained models to measure the models' accuracy on unseen data. The result showed that the best accuracy both on validation and test data, more than 98%, was reached with neural networks and ensemble classification models.
Development of Human Resources is being given due importance by all the organizations as it aims at developing all the employees of an organization in a planned manner to acquire, sharpen and apply their existing capabilities as well as their inner potentials. HRD is a total system in which its various mechanisms are embedded together to act as an integrated unit. No sub-system can work in isolation. The researches show that the working of each sub-system has its impact on other subsystems e.g. Performance appraisal is basis for assessing training needs, career planning etc. Training is useful tool for increasing individual efciency. It is also a part of employee welfare and is used for promotions. Implementing these HRD sub-systems helps in developing a climate in the organization where the people collaborate with each other; respect and trust others and work as a team. This, in turn, develops a highly positive and motivated workforce which enables the organization to achieve its goals. Human being is a creature composed of heredity and environment and creates values for their own. In the context, during the interactions with others, the values manifest spontaneously. Human beings are tempted by all kinds of emotions, impulses, instincts, prejudices, wishful thinking, hopes, fears, desires, and almost everything.
A study to evaluate the influence of body mass index, life styles and dietary habits on blood pressure among the nursing students at selected nursing college of Vijayapur. The objective of the study is to assess relationship of life style factors, body mass index and dietary habits with blood pressure. A sample of 500 nursing students was included in the study. The study result showed there is significant association between body mass index, life style dietary habits and blood pressure
Cet article s’intéresse à la fréquence, aux fonctions de l’alternance codique chez l’enseignant d’espagnol en classe de quatrième (débutants) et aux activités pédagogiques au cours desquelles apparaît ce phénomène de contact de langue. Notre investigation porte sur 80 enseignants d’espagnol et 1000 élèves hispanophones de la région de San Pedro en Côte d’Ivoire. Pour ce faire, nous avons opté pour l’analyse quantitative et qualitative. La première méthode par le biais du logiciel SPSS a permis de constituer une base de données. Ainsi, il ressort que 51 soit 63,1% des enseignants utilisent 5 à 10 % du temps du cours pour s’exprimer en français. Aussi, ces enseignants alternent-ils plus ces deux langues pendant les activités de compréhensions de texte, et vocabulaire soit 32,1% de l’effectif. Quant à l’analyse qualitative de type conversationnel, elle a servi à proposer quelques fonctions d’alternance codiques pendant les activités d’interaction.
Background: E-waste, is the waste generated from used electrical and electronic devices that are no longer fit for their original intended use. Currently e-waste comprises more than 5% of total municipal waste flow, equivalent to 20-50 million tonnes annually worldwide. In 2014, Nigeria generated about 219 kilo tonnes of e-waste. The study aimed to increase public awareness on the need for proper management of e-waste because of its hazardous nature. Methods: This was a cross-sectional study in Enugu West Senatorial District of Enugu State comprising Oji-River, Ezeagu, Udi, Awgu and Aninri Local Government Areas with a population of 980,988. An adaptation of the UNEP, EMPA and Basel convention questionnaire, administered to 400 households was used for data collection. Results: The potential e-waste generation in the study area was 0.05 kg per inhabitant. 76% of the households were aware of the hazards of e-waste. 64% were willing to give out their e-waste to waste collectors. Only 26% of the e-waste were collected with the general waste. The correlation between awareness of the hazards of e-waste and willingness of the households to give out their e-waste was positive, moderate, and insignificant (r= 0.43, p=0.47). Conclusions: Although 76 per cent of the households were aware of the hazards of e-waste, with 64% willing to give out their e-waste, only 26% of the e-waste were eventually collected together with the general waste. There is a need to create a separate e-waste collection system.
The emergence of big data has caused various challenges to data management lifecycle including storage, processing, sharing, and applications. During the same time frame, the fast development in cloud computing provides increased efficiency in computing support that address these challenges. However, there are issues in big data and cloud computing management which include security concerns, data fragmented, and distrust in using clouds that could become the roadblock to e-government services success. Although ensuring data management has been the responsibility of providers in the public sector, this issue seems to be unavoidable. In such circumstances, initiatives from the public sector agencies are crucial to ensure data is effectively managed. This research in progress aims to investigate how the public sector agencies in Terengganu manage data to improve the e-government performance. The research uses the interpretive research paradigm and adopts the qualitative research methodology using a case study design. A single case of a public sector which utilizes big data and cloud computing within the e-government platform is selected as the case for this research. The findings of this research are expected to be used in developing a framework of big data and cloud computing management which will assist in providing reliable and accurate information to citizens within the e-government environment.
Vallecular cysts, although infrequent in adults, pose a challenge for anesthesiologists in view of the risk of airway obstruction at anesthesia induction or aspiration in case of cyst rupture. The present case is of a 35-year-old male patient who was scheduled for excision of a vallecular cyst. An awake technique was initially decided for nasotracheal intubation using a flexible videolaryngoscope, AmbuscopeTM, after complete topicalization of the airway with local anesthesia. However, anticipating the need for a tracheostomy, the surgical team was prepared, and this was timely chosen as the only viable option following failure to visualize the glottis despite negotiating every possible way around the cyst. This case highlights the successful management of a large vallecular cyst in an adult patient, where failed awake nasotracheal intubation despite optimal preparation necessitated an early, planned tracheostomy. This reiterates the fact that the surgical airway may not be always chosen as the last resort in crisis but also as a timely intervention to prevent an airway catastrophe.
Nano technology refers to enhancing the function and delivering the upcoming smart solutions to products at the nanoscale level. It relates to organizing the molecules for altering in dimension and characteristic for improvement like smart fabric. These fabrics could assist producers with the added prominence on a standard of living, visual attraction, and system wanted technological produces. Nanosize particles can unveil unpredicted characteristics dissimilar from the bulk matter. The fundamental principle is that the features could radically be altered after the material is decreased to the nanometer scale. Nanotechnology has multipurpose functions in fabric manufacturing in producing the stain and wrinkles defiance, flame retardant, antimicrobial and antistatic properties, moisture control, ultraviolet protection, and release features. The nanomaterials inside the fabric could influence numerous qualities, comprising reduction, electrical conductivity, flammability, and strength. Nanotechnology has additionally created a significant impression on various application and implementation. Nano-doctored fabrics may advance numerous fabrications as the nano-science progresses further.
The daily water distillation of the single basin conventional solar still is limited. In the present work, experimental analysis of a parabolic disc type solar still and conventional solar still are investigated. The solar radiation is focused to the single point to produce higher basin temperature. The water is flown continuously inside the copper receiver to utilize the incident solar radiation. The hourly readings were taken to analyze the thermal performance of the parabolic disc type solar still and conventional solar still. The water collection of parabolic disc type solar still is increased about 40% over conventional solar still.
Background Urban legends and myths are prevalent in drug-use environments. However, the distinction between myth and fact is not always clear. We found contradictory claims regarding the emergence of cold cook methods for producing methamphetamine when contrasting user-generated reports with official reports repudiating such methods as myths. Our aim is to open the topic for more academic discussion. Methods We examine cold cook methods of methamphetamine production revealed in our ethnographic study and interviews with former (n = 50) and current (n = 48) methamphetamine users. Data were collected in the suburbs of a large southeastern city in the United States. We compare the data with reports from law enforcement professionals and public health officials. Results Official reports claim the cold cook method described by users in our study is a myth and does not produce methamphetamine. Small-scale producers sell it as methamphetamine and users claim it has the same effect as methamphetamine. They are charged for possession and distribution of methamphetamine when caught with this drug. It appears the unintended consequences of recent policy aimed to reduce production and use of methamphetamine may be a user-friendly production method. We do not know the health implications at this time. Conclusion We do not make any definitive conclusions on the legitimacy of the stories or myths discussed here but instead suggest that labelling drug stories as myths might lead to dismissing facts that hold partial truth. The subsequent dismissal of cold cook methods among policy and public health officials risks a range of unintended consequences among vulnerable populations. We present our case for more research attention on the myths of methamphetamine production. Keywords: Cold Cook Methods, Cold Cook Methods step by step, Cold Cook Methods steps, Methamphetamine, Cold Cook Methods list
Malignant melanoma is the most dangerous type of skin cancer. It is becoming more common globally and is increasingly resistant to treatment options. Despite extensive research into its pathophysiology, there are still no proven cures for metastatic melanoma. Unfortunately, current treatments are frequently ineffective, costly, and have several adverse effects. Natural substances have been extensively researched for their anti-MM capabilities. Chemoprevention and adjuvant therapy with natural products is an emerging strategy to prevent, cure or treat melanoma. Numerous prospective drugs are found in aquatic species, providing a plentiful supply of lead cytotoxic chemicals for cancer treatment. Anticancer peptides are less harmful to healthy cells and cure cancer through several methods, such as altered cell viability, apoptosis, angiogenesis/metastasis suppression, microtubule balance disturbances and targeting lipid composition of the cancer cell membrane. This review addresses marine peptides as effective and safe treatments for MM and details their molecular mechanisms of action.
Purpose: Congenital hypogonadotropic hypogonadism (CHH) is a rare genetic disorder mostly characterized by gonadotropins release and/or action deficiencies. Both isolated (idiopathic hypogonadotropic hypogonadism) and syndromic (Kallmann) forms are identified depending on the olfactory ability. Clinical and genetic heterogeneities of CHH have been widely explored, thus improving our understanding of the disease's pathophysiology. This work aims to (1) provide a detailed clinical and hormonal description of normosmic CHH patients and (2) identify the mutation linked to the studied phenotype. Participants and methods: We investigated three affected patients with normosmic CHH, belonging to a consanguineous Tunisian family. Patients underwent an insulin-induced hypoglycemia test. We performed whole exome sequencing to identify the causal mutation. Results: At first diagnosis, a total gonadotropic deficiency was identified in all patients. The insulin-induced hypoglycemia test has also revealed a reduced cortisol secretion and complete growth hormone deficiency. At 20.8 years, one female exhibited a spontaneous recovery of the hypothalamic-pituitary-adrenal axis function, unlike her affected siblings who still depend on corticosteroid replacement therapy. Herein, we identified a novel homozygous nonstop mutation (c.1195T>C) in KISS1R gene in all affected subjects. This mutation led to the substitution of the physiologic stop codon by an arginine (p.X399R). Conclusions: Our study highlights the importance of the KISS1R signaling, in gonadotropin-releasing hormone neurons, in the control of reproductive function. Additionally, our data suggests a complex central and peripheral metabolic control of puberty, through the hypothalamic KISS1R signaling. We suggest a mutual link between the hypothalamic-pituitary-gonadal, -adrenal, and -somatotropic axes.
Lytic lesions in adult spine are a common manifestation of aggressive disease such as primary bone tumor, metastasis, myeloma, or infectious pathology. Xanthoma arising in the spine with purely intraosseous component is an extremely rare occurrence with only six cases reported in the adult population, none in the cervical region. We report the first case of primary xanthoma of the cervical spine in a 50‑year‑old male solely confined to osseous compartment. The imaging mimics of lytic lesion with expansile mass in adult spine are reiterated.
Melilotus officinalis (L.) Pallas. is used traditionally to treat hypertension and chronic venous insufficiency. The high prevalence of hypertension and the side effects of antihypertensive drugs potentiate us to evaluate Melilotus officinalis. The hypotensive effect of Melilotus officinalis butanol fraction (MOBF) was investigated in anaesthetised normotensive rats. The doses of 60, 80 and 100 mg/ kg, i.v., produced a significant (P<0.05) decrease in blood pressure. The statistically non-significant reduction in blood pressure was shown by 20 and 40 mg/ kg, i.v. These results suggest that Melilotus officinalis exhibited a hypotensive effect in normotensive rats. However, further evaluation of compound-related activity is required.
Though the anatomy and physiology of the adult caprine (Capra hircus L.) stomach have been investigated extensively, the early development of the abomasum has not yet been fully elucidated. The glandular part of abomasum plays an important role in digestion of ingested food by action of gastric juices. Very few studies have been conducted so far regarding histogenesis of goat foetal abomasum in India. In the present study, we have investigated the embryonic and early foetal development of the goat, Capra hircus L. fundic abomasum. We collected 36 developing abomasum of healthy and normal embryos/foeti of goat and assigned them into three group viz. Gr. I (0-50 days of gestation), Gr. II (51-100 days of gestation) and Gr. III (101-150 days of gestation). Small pieces of tissues were processed by routine paraffin. The wall of glandular stomach, the fundic part, was composed of epithelium, pleuripotent blastemic tissue and serosa up to 44 days of gestation. Tunica muscularis became separable at 46 days of gestation. The epithelium was stratified type up to 50 days and gradually changed to pseudo-stratified columnar to simple columnar type from 76 days of gestation. Primary and secondary abomasal folds were observed at 51 and 76 days of gestation, respectively. Gastric pit, the fore runner of gastric gland was reported first at 70 days. The gland became branched tubular type at 145 days. The cells found in the mucosa of the abomasum were surface epithelial cells, chief cells, parietal cells, mucous neck cells and undifferentiated cells. Chief and parietal cell were observed at 76 days and mucous neck cells at 82 days of gestation. Reticular, collagen and elastic fibers came into sight at 38, 76 and 100 days of gestation, respectively. The present study is expected to supplement known data and knowledge regarding histogenesis of goat fetal abomasum and help in diagnosis and treatment of related congenital anomalies.
The Cellular Manufacturing is adopted in batch type manufacturing industries nowadays for their production with increased productivity, less cost and time with effective control. The proposed optimization model is used to determine the cost of machine cells, i.e., machine duplication, part subcontract, inter intra cellular movements cost and cost of production associated with machine cell, such as machine reconfiguration and part inventory considering machine flexibility for various time periods. Initially, a mathematical model is proposed to calculate machine cell cost with and without considering machine flexibility, and then another lpp integer model is proposed to calculate the machine cell production and associated cost for the changes in the time period, part type, and volume considering machine flexibility. The manufacturing data in the incidence matrix and machine cell, and part family data in the block diagonal form are given as input to the optimization programming language Cplex and the output is given for the two mathematical models. The data relating to machine duplication, part subcontract, inter intracellular movement; machine reconfiguration, and part inventory are given. Two-dimensional shop floor layouts are presented in rectilinear coordinates for all the problems for easy analysis of material movement length and shop floor area
Background: There is a lack of adequate data about the prevalence and types of tuberculosis (TB) disease in Hadramout Al-Sahel, Yemen. Hence, this study aimed to investigate the prevalence, types, and outcomes of TB disease in Hadramout Al-Sahel, Yemen. Materials and Methods: This cross-sectional study was conducted at the National TB Program (NTP) center in the city of Al Mukalla, Hadramout, Yemen. The study enrolled TB patients from different districts of Hadramout Al-Sahel who had registered at the NTP center between January 1 and December 31, 2021. Results: A total of 127 new active TB cases were recruited, including 102 (80.3%) with pulmonary TB (PTB) and 25 (19.7%) with extra PTB (EPTB). The overall prevalence of TB disease in 2021 was 12.7 new TB cases per 100,000 population, while the median age of the study population was 38 years. The majority of cases (23.6%) belonged to the age group of 35–44 years. There were 85 (66.9%) males, and most patients (74; 58.3%) were identified in Al Mukalla City. EPTB was detected in 25 (19.7%) patients, with pleural effusion being the most frequent manifestation, found in 12 (48.0%) patients. All patients received 4-agent anti-TB therapies; 99 (77.9%) patients received anti-TB therapy for 6 months; 9 (7.1%) patients received anti-TB therapy for 9–12 months; 8 (6.3%) patients died during treatment; and 11 (8.7%) patients were lost during follow-up. The majority of patients (108; 85%) were cured on completion of treatment. Conclusion: The prevalence of TB in Hadramout Al -Sahel was 12.7 cases per 100,000 population. Males were affected more than females; the pleura was the most commonly affected extrapulmonary site; and 85% of cases were cured. The results indicated the need to support the Al Mukalla NTP center, by providing more resources for improved TB reporting and for conduct of surveillance to detect new TB cases among high risk groups. Health authorities are also urged to provide state hospitals with the equipment needed for TB diagnosis.
This study investigated workforce diversity and secondary school administration in Rivers state. The design for the study was the descriptive survey. Two research questions and two hypotheses were raised to guide the study. Mean and standard deviation statistics were used to answer the research questions while the hypotheses were tested at 0.05 level of significance using z-test statistics. A sample size of 667 respondents, representing 90% of the entire population of 741 principals and vice principals from all the 247 pubic senior secondary schools in Rivers state was drawn using the stratified random sampling technique. A researcher-designed instrument titled Workforce Diversity Management Questionnaire (WOFDIMQ) was used for data collection. The instrument was validated by experts in the area of measurement and evaluation at the University of Port Harcourt. The reliability index determined for the instrument using Cronbach Alpha was 0.82. The findings of the study revealed that secondary school administrators do have some administrative strategies put in place for the management of the diversities among teachers. It was therefore recommended among others, that the government should make some specific provisions that will guide school administrators in the management of diversities among teachers. Also, school administrators should develop operational plans and strategies that are based on their specific peculiarities that will help maximize the advantages of diversities among teachers, while at the same time, minimize the inherent disadvantages.
The current study used the chick emesis model to explore the anti-emetic effect of the methanolic extract of Acalypha ornata Hochst—roots. Emesis was induced by the oral administration of copper sulfate to male chicks. Acalypha ornata root extract (150 mg/kg orally) showed an anti-emetic effect and was compared with the reference drug chlorpromazine