Cardiovascular disorders are known as one of the leading health problems which are associated with mortality worldwide. Myocardial ischemia (MI) is the improper blood supply to the myocardium, which leads to severe complications to life-threatening problems like AMI, atherosclerosis, hypertension, cardiac hypertrophy, as well as diabetic-associated complications such as diabetic atherosclerosis/cardiomyopathy/hypertension. Despite several efforts, the current therapeutic platforms are unrelated to significant results. Hence, it seems that developing novel therapies is required. Increasing evidence indicates that curcumin (CRC) acts as a cardioprotective agent. Given that CRC and its analogues exert their cardioprotective effects via affecting various cardiovascular disease-related mechanisms (i.e., Inflammation and oxidative stress). Herein, we have highlighted the protective impacts of CRC against MI for the first time. This review might be a stepping stone for further investigation into the clinical implications of the CRC against MI. Furthermore, it highlights a legitimate concern for the scientific community, seeking novel techniques and characteristic dynamic biopharmaceuticals against myocardial ischemia.

Dr. salman ahmed

The current study was designed to explore the analgesic effects of methanol extracts from the leaves of Samanea saman Merr. and Prosopis cineraria Druce., using tail immersion test. Thermal stimuli produced painful reactions in mice by dipping the tail tips of the mice into hot water. Methanol extracts of the leaves of Samanea saman Merr. and Prosopis cineraria Druce. were administered intraperitoneally at the dose of 100mg /kg body weight. Pethidine 50mg/Kg intraperitoneally was used as a standard analgesic drug. The tail-flick latency delay was measured at 0.5, 1.0, 1.5, 2.0, 2.5 and 3.0 hours after the intraperitoneal administration. Both extracts produce analgesic effects when compared with pethidine.

Dr. salman ahmed

COVID-19 is associate communicable disease caused by severe acute respiratory syndrome coronavirus. It's currently a virulent disease unfold moving several countries globally. The aim of this study is to assess the knowledge and practices of COVID-19 among general public at the selected setting, Chennai. The main objective was to assess the knowledge and practice on COVID-19, correlate the knowledge with practice on COVID-19, and associate the knowledge and practice on COVID-19 with the demographic variables among the public. A Quantitative non-experimental analysis style was used to assess the knowledge and practice of COVID-19. Sixty individuals were chosen through the non-probability convenience sampling technique. The findings of the analysis disclosed that the majority (40%) of the samples had a high level of knowledge and 43.3% of them had a good practice, 33.3% of them had a moderate level of knowledge and 30% of them had moderate practice, whereas 26.7% of them had a low level of knowledge and 26.7% of them had poor practice on COVID 19. Keywords:- COVID-19, Knowledge, Practice, Pandemic, General Public.

Elsi queen

Konsep edutainment mencoba memadukan antara pendidikan dan hiburan, yang didalam konsep edutainment tersebut terdapat beberapa pendekatan yang lebih kita kenal sebagai SAVI (Somatik, Auditori, Visual dan Intelektual). Metode penelitian ini menggunakan jenis penelitian Library research, yaitu jenis penelitian yang dilakukan dan difokuskan pada penelaahan, pengkajian dan pembahasan literature-literatur, baik klasik maupun modern. Literature berbahsa arab, inggris, Indonesia dan sebagainya yang ada kaitannya dengan persoalan ini. Penelitian ini bersifat analisis deskriptif. Sumber data penelitian ini yaitu: Sumber primer dari pemikiran Beby De Poter. Sumber skunder meliputi: buku, artikel atau esai yang membahas konsep edutainment, dan buku yang berkenaan dengan konsep psikologi belajar anak, serta buku pendidikan karakter, terutama karakter cinta tanah air. Hasil penelitian ini menunjukkan: (1) Pembelajaran Edutainment Dalam Penanaman Karakter Cinta Tanah Air Bagi Anak Usia Dini Di Sekolah Dasar, yaitu: menumbuhkan karakter cinta tanah air, memunculkan emosi minat anak seperti rasa senang dan gembira dalam pembelajaran, guru dalam menyampaikan pembelajaran di kelas harus menunjukkan sikap kepedulian terhadap peserta didik. (2) Proses Penanaman Karakter Cinta Tanah Air Bagi Anak Usia Dini Di Sekolah Dasar, yaitu: proses pembelajaran interaksi antara siswa dan guru terbangun suasana menyenangkan, fleksibiltas guru dalam menyampaikan materi menyesuaikan dengan emosi peserta didik, hubungan keakraban dan persahabatan sebagaimana teman sendiri, dan guru memberikan kebabasan berexspresi kepada perserta didik pada saat proses pembelajaran.

Educare: journal of primary education

Cleome brachycarpa Vahl . and Cleome viscosa L. were evaluated for anti-emetic activity in the copper sulfate-induced chick emesis model. Emesis was induced by copper sulfate (50 mg/kg), and the methanolic extracts of leaves were tested orally at a dose of 150 mg/kg. Chlorpromazine (150mg/kg orally) was used as standard anti-emetic drug. The anti-emetic activity was determined by calculating the mean decrease in the number of retching as compared with the control. Cleome brachycarpa and Cleome viscosa showed comparable anti-emetic activity with chlorpromazine.Cleome brachycarpa Vahl ., and Cleome viscosa L., leaves extract in a dose of 150 mg/kg body weight., reduced the numbers of retches by 57.57% and 43.06%. Cleome brachycarpa significantly (**P<0.005) reduced the number of retches. The group of chicks treated with chlorpromazine had 45 retches compared to the 71 retches of the control group, thus chlorpromazine reduced the retches by 36.99%. From the results, it is clear that Cleome brachycarpa Vahl. and Cleome viscosa L. leaves extracts have antiemetic potential and are comparable with standard chlorpromazine. Although the result is significant the mode of action is not known. Antiemetic activity by using copper sulfate proposed 5-HT3, 5-HT4, or NK1 receptor antagonism. Therefore, the extracts effectively prevented its effect and had a peripheral anti-emetic action. As mentioned earlier, triterpenoids such as brachycarpone, deacetoxybrachycarpone, cabralealactone and ursolic acid are reported from Cleome brachycarpa6, whereas flavonoids are reported from Cleome viscosa. Flavonoids and triterpenoids possess anti-emetic properties18. So, if flavonoids and triterpenoids are present in the studied extracts, the observed anti-emetic effects may be due to flavonoids and triterpenoids. The present study is on the preliminary level, and further investigation is required to confirm the anti-emetic effect of Cleome brachycarpa Vahl ., and Cleome viscosa L. leaves and determine the compounds responsible for this activity with their possible mode of action.

Dr. salman ahmed

Artificial Intelligence (AI) is rapidly transforming the landscape of supply chain management, offering unprecedented opportunities for optimization, efficiency, and innovation. This white paper explores the various applications of AI in supply chain operations, highlighting its potential to revolutionize the way businesses manage inventory, logistics, demand forecasting, and more. Through real-world examples and case studies, we demonstrate how AI-driven technologies are reshaping traditional supply chain practices and driving competitive advantage in today's dynamic marketplace.

Kalpak

Apprenticeship is one way of learning by doing. The Student Apprenticeship Program (SAP) or Apprenticeship as referred to in this study is a curricular program of the Institute of Accounts, Business and Finance (IABF) of the Far Eastern University - Manila. It aims to enhance the preparation of the students for actual employment after college graduation. A study was conducted on the sixty-nine (69) Business Administration interns of a private university in Manila during the first semester of academic year 2017 - 2018. Performance Evaluation Forms were distributed to all the supervisors of host companies. Evaluation forms were personally monitored by the Apprentices Adviser which made it possible to collect a 100% response. A sort of quantitative analysis was used to analyze the information provided for in the evaluation forms. The purpose of this study is to assess the interns’ performances and skills as well as their strengths and weaknesses based upon the personal and direct observation by the supervisors of the various host companies. This study will also find the gap in the interns’ skills based upon the Institute expectation and observation by the supervisors. The study is limited to one time observation by supervisors of various host companies. This study is underpinned by sociocultural theory, cognitive apprentice theory, situated learning theory and the 21st Century Skills Framework.

Dr. leonardo f. cada, jr.

Front line demonstration is an appropriate means for demonstration as well as transfer of improved agricultural innovations to the farming community. Under centrally sponsored schemes on oilseed production technology under NFSM schemes, KVK Athiyasan, Nagaur-I conducted 425demonstrations on mustard covering 180 ha areaduring Rabi, 2015-16to 2019-20. The critical inputs were identified in existing production technology through discussion with farmers and on the basis of soil sampling. Lack of plant protection measures were the predominant identified causes of low productivity of oilseed crop in district Nagaur. In the same sequence the other parameters like technological impact, economical impact and extension gap were analyzed for impact assessment of frontline demonstration (FLDs) on mustard crop. The results of five consecutive years study revealed that the demonstration plots produced on an average 1954 kg/ha mustard grain yield, which was 22.51% higher compared to prevailing farmers practice (1597 kg/ha). The average increase in gross return, net return and cost of cultivation was in the tune of 22.36, 31.08 and 6.43 per cent, respectively. Further, data indicated that the average additional cost of cultivation (Rs. 1435/ha) under integrated crop management demonstrations and has fetched additional net returns of Rs. 12659 per hectare with incremental benefit: cost ratio of 0.41. The average technology gap, extension gap & technological index were found 636kg/ha, 356kg/ha and 24.44percent, respectively. The results clearly indicate the positive effect of FLDs over the existing practices.

Dr. babu lal jat

Recession affects many factors; it affects the export, Slowdown of the industrial production, which result into slowdown of growth. Human resource management is responsible for how people are treated in organizations. It is responsible for bringing people into the organization, helping them perform their work, compensating them for their labours, and solving problems that arise. Recession presents a very difficult time for any existing organization in today’s corporate world and no company is exempted from this truth. The biggest challenge for companies and especially Human Resource in this economy downturn is to survive and to remain competitive, companies reorganized and reengineered to reduce waste. Recession poses unique challenges to the HR department. HRM strategies & innovations providing a wide selection of employees, employers, customers, suppliers etc. in all ranges This paper outlines the transformation of HRM strategies and innovations in Asia. Beginning with its inception, the paper is progresses towards its various HRM functions like recruitment and selection of employee, training and development, compensation and benefits, growth of Human communication, This paper also highlights HRM strategies to counter intensified competition and external conditions like global economic recession, the resultant credit crunch and its impact on employee performance.

Dr. pankaj shyamlalji vishwakarma

Lightweight materials are increasingly being used in engineering applications today. Composites are replacing traditional metallic materials in a variety of sectors, including aerospace, defence, and aircraft production, where there is a demand for structural materials with high strength-to-weight and stiffness-to-weight ratios. Natural fibre composites are also increasingly used in place of synthetic fibre composites in a variety of technical fields due to their affordability and environmental friendliness. In this particular study, Kevlar (Aramid fibres) is combined with other materials to improve the mechanical characteristics and impact resistance of composites. The only material that costs more than Kevlar is carbon fibres. The goal is to maximize mechanical qualities while utilizing the fewest amounts of pricey Kevlar fibres possible. The hand layup technique was used to create the hybrid composites, which included both natural and Aramid fibres. The performance of various mechanical properties was then assessed. In addition, a morphological examination was done to look at the interior structure of the composite materials that were examined. The results show that the hybrid composite, with or without the addition of nanoparticles, demonstrates great strength with little reliance on Kevlar fibres.

Boopathy govindarajan

Before the start of the SARS-CoV-2 (COVID-19) pandemic, the whole environment around us had been deemed very toxic to breathe in due to the amount of greenhouse gases that had been emitted over the centuries. The Earth faced rising temperatures, which in turn led to the melting of glaciers and rising of sea levels. Environmental degradation was happening fast due to the depletion of resources such as air, water and soil. But after the coronavirus lockdown (Talabandi) commenced, there have been changes in the environment. The lockdown still has a huge impact on people in India too. The halt of industrial production and traffic resulted in cleaner air and rivers. In India the first phase of the nationwide lockdown that began on March 24 followed by enforcement of a series of regulations had some evidences that the COVID-19 curve is flattening in the country's COVID-19 affected regions. There was a good chance Prime Minister Narendra Modi extended the lockdown (Talabandi) four times that ended on (Phase 1 (24 March-14 April)., Phase 2 (15 April-3 May)., Phase 3 (4 May-17 May) & Phase 4 (18 May-31 May). The paper focuses on different aspects of environmental impact due to SARS-CoV-2 in India.

Rina kumari

Organisations may either belong to the private sector or the public sector. When they are in the private sector, they can be large, small or medium-sized depending on the annual income and the number of workers they hire. Global organisations are developing rapidly because of the need to tap into new markets and production locations. Under the organisational structure, the organisation selected was Nike. It has several functional units whose activities are interrelated. For instance, human resource units ensure that the right personnel for finance or marketing are recruited and promoted. The emergence of new markets in BRIC and the digital revolution are highly relevant to external factors that affect the organisation. As a response, Nike has used social media and the digital revolution to reach customers directly. It, however, needs to take on new markets and products to remain in business.

Zamzam abdelazim

By using mathematical vectors calculations as financial modeling then further into a new form of quantitative analysis instrument for linear financial computation graphs. A new tool in financial data analysis as an indicator

Dr abdul rahim wong

The soil samples were collected from Melia dubia plantations in two different locations in Tamil Nadu. A total of twenty five actinomycetes isolates were isolated and they were screened for melanin pigment production using different culture media. Only two isolates were able to produce melanin pigment under in vitro study and one isolate showed positive reaction to L-tyrosine substrate. Based on morphological and bio-chemical characters the isolate was identified as Streptomyces sp. The DNA of the isolate was isolated and its 16S rDNA gene was amplified and sequenced. The phylogenetic analysis of Streptomyces puniciscabiei was carried out.

Dr. saranya devi k

Poor water quality and lack of access to improved sanitation continue to pose a significant threat to human health. The burden of disease analysis suggests that lack of access to safe water supply, sanitation and hygiene is the third most significant risk factor for poor health in developing countries with high mortality rates. Diarrhoea is the leading disease associated with unsafe water supply, sanitation and hygiene and is responsible for the deaths. The study observed that out of the 150 respondents, 37% are 31-40 years, followed by 20-30 years with 32%. 130 (86.7%) respondents have got married, and 61% of the respondents are female. 85% adopted the nuclear family system, and 50% of respondents are illiterates in the study areas. 85% of respondents are daily wage earners, 37%are earnings rupees between 2000-2500 per month. 27% of respondents are landless labours, and 37% of households possess below 2 acres of land. 40% of respondents suffer from health problems, and 44% consume rice as their staple food. 62% of respondents have debts, and 33% got from money lenders. 62% of respondents do not have toilet facilities and go open defecation. 92% of respondents stated that toilet makes dignity, saves time and energy, saves their children school days, makes adolescent girls privacy, save wage loss, and toilet makes quality life.

B suresh lal

Geotextiles have been successfully used for reinforcement of soils to improve the bearing capacity. In this study geotextile as a tensional material have been used for reinforcement of granular soils. Laboratory California Bearing Ratio (CBR) tests were performed to investigate the load-penetration behavior of reinforced soils with geotextile. Samples of granular soil are selected and tested without reinforcement. Then CBR tests were performed by placing geotextile in one or two layers at various depths in soil sample. The effect of the number of geotextile on the increase in bearing capacity of reinforced granular soil is discussed.

Mayura

Creating a strong business and building a better world are not conflicting goals – they are both essential ingredients for long-term success. Canara Bank is one of the leading banks in the banking sector which is serving a lot of customers. The initiatives of the Bank under CSR have been the setting up of Trusts and Institutions which have created an impact in serving the people and society at large.Bank has been engaging employees and motivating them employees for participate in CSR activities. Bank has established a Community Development Section’ under FI Wing whose activities include organizing blood donation camps, health check up camps, career guidance and many more. The objective of this paper is to resolve the activities initiated by Canara Bank and the funds allotted in various areas.

Vidya bhat

The rapid growth of wireless devices introduces a diverse range of applications and requires intelligent hardware platforms that integrate computing, sensing, and wireless connectivity in a compact systemon- chip (SoC). This paper presents a low-power, high-performance SoC platform that supports dynamic power management and secure communication. The SoC platform consists of 16-/32-bit programmable ARM9 cores, a power management unit with multiple low-power modes, analog and digital peripherals, and security engines. A complete tool-chain with an automatic platform generator has also been developed to ease and accelerate the application development. Fabricated in a 65 nm CMOS technology, an implementation of the proposed platform occupies an area of 1.0 × 1.7 mm2.

Dr h shaheen

Mosquitoes conveying Plasmodium store parasites into the skin of the mammalian host. Parasites make a trip through the circulation system to the liver, where they cross a few hepatocytes prior to building up a disease. Inside the last hepatocyte the parasite goes through morphogenesis and afterward abiogenetically partitions to become more than 20,000 blood-infective parasites, called merozoites. On account of P. vivax, P. ovale, and P. cynomolgi, the parasites can stay lethargic in the liver in structures called hypnozoites. The merozoites are delivered once again into the circulation system, where they start the repetitive blood stage. Inside erythrocytes, a little division of parasites separate into male or female gametocytes. These gametocytes are ingested by the mosquito during blood taking care of, where they will duplicate explicitly, in the long run prompting the arrangement of sporozoites

Rukshi naaz

The research paper has addressed the issues related to the usage patterns of the social media by the college students. The demographic profile of the students is also been studied in order to identify the relationships. The most used social media, duration of the use of social media, time spent on the social media, the reliability of the information shared on the social media, number of friends and the groups students have on social media their preferred time of using social media are the major issues discussed in the paper. Primary data is used for the calculations and analysis which is collected through the questionnaire circulated among 500 students studying in graduate level pharmaceutical science course. The study is descriptive in nature and qualitative as well as quantitative research methods are used to study the objectives. The study presents new data on Internet use among male and female college students, as well as trends in use of social media. The findings of the paper indicate that there exists a strong link between the gender of the respondents and most used social media. The data analysis gives a clear picture about the typical pattern of using social media in terms of the time, occasion, number of friends and groups they belong to on social media.

Nitin mali