Distributed Generators (DGs) are incorporated in the power distribution systems to develop green energies in microgrids. Islanding is a challenging task in a microgrid. Different types of islanding methods, e.g. local and remote methods, have been developed for handling this task, with local methods being easier to implement, while remote methods are communication-based and costly. The local methods are classified as passive, active, and hybrid, out of which the passive methods are more simple and economical. In this paper, a passive islanding detection method is proposed to detect single line to ground fault. This fault is considered to represent the 60 to 70% of the total un-intentional faults of this category. The available passive methods cannot detect islanding at lower power mismatches as the variations in voltage and frequency fall within thresholding values. In this method, the voltage signals are first retrieved at the targeted DG output and then the phase angle is estimated. Finally, the phase angle is differentiated to get Rate Of Change Of Voltage Phase Angle (ROCOVPA) to detect islanding, and then it is compared with the Rate Of Change Of Frequency (ROCOF) at zero percent power mismatch. Simulation results depict that the ROCOVPA is more effective than ROCOF. The proposed method not only reduces detection time and NonDetection Zone (NDZ) but is also stable during non-islanding cases like load connection and disconnection to avoid nuisance tripping.
The main objective of this study is to examine the relationship between globalization, resource conflicts and peace –building in Africa, with particular emphasis on Nigerian’s north-central geo-political zone. The wave of globalization that has swept across the world with its attendant socio-economic and political consequences lies at the heart of this study. The debate that is raging currently amongst intelligentsias, public analysts, and the international community point to the fact that the global system has suffered increasing setbacks occasioned by the impacts of globalization and contestation for scarce natural resource endowments. The changes that have emerged for several decades in both developed and developing nations, with the latter having a greater share of repercussions, have remained largely daunting. The multiplier effects of these changes have resulted in worsening crisis situations, with a fast growth rate of intra-state and/or trans-regionalized networked conflicts, which is why Africa and indeed Nigeria, has become a hotbed for contestations recently. This work adopts a qualitative approach as a method of investigation. This work relies on classic works of experts in the broader discipline of globalization and conflict resolutions, the essence of which is to clearly define ways of ensuring absolute peace in Nigeria’s north-central zone. The paper observes that guaranteeing peace-building requires the adoption of both vertical and horizontal approaches as templates for the realization of peace objectives.
Introduction: Psilocybin mushroom use is well documented in spiritual and religious ceremonies globally. This drug is now the most popular in Europe and the USA. Objective: The objective of this study is to explore the experiences and effects of psilocybin on patients with depression and anxiety. Method: A qualitative study was conducted interviewing ten participants currently taking psilocybin while experiencing depression and/or anxiety. Ethical approval was obtained from the University ethics committee. Participants were recruited via social media and groups are known to have used psilocybin for the treatment of anxiety and/or depression. Participants were informed of study aims and consent was obtained before interviews commenced. Confidentiality was maintained throughout this study. Interviews began with informing participants that psilocybin may be effective in the management of depression. Initially, information around the way treatment with psilocybin was obtained was sought. This was followed by queries around the effects of the drug in terms of experiences both during and after treatment. Finally, participants were asked to outline the positive effects of psilocybin on their lives. Results: The data were thematically coded using Grounded Theory as an underpinning philosophical paradigm. Emerging themes included enhancement of smell, vision, hearing, and taste sensations. Another theme emerging was the experience of being ‘connected with the universe’ while on the drug. Additionally, participants reported a stabilization of mood, an increase in optimism and emotional control, and a healthier emotional connection with others. Most also felt an increase in comfort, peace and calmness. Another theme that emerged centered on the mechanism of action of psilocybin. Participants stated that this substance seemed to ‘make new connections in their brain,’ resulting in new perspectives. Some participants felt this resulted in a calming influence on the mind and body. This aligns with research showing that psilocybin works by changing the thinking and improving information processing. Conclusion: Psilocybin has promising effects on the patients with depression/anxiety even after a single dose. Psilocybin is safe but the administration should be guided by a health professional to yield safe and positive outcomes.
Toxicity of different insecticides was evaluated against 2nd and 3rd instar larvae of Helicoverpa armigera under laboratory conditions by leaf dipping method. The insecticides viz., thiodicarb 75WP, novaluron 10EC, spinetroam 11.7EC, indoxacarb 15.8EC, quinalphos 25EC, rynaxypyr 18.5SC, emamectin benzoate 5SG and cypermethrin 25EC were tested. Spinetoram was found most effective in managing the 2nd instar larvae of H. armigera and it was followed by novaluron 10EC and indoxacarb 15.8EC as compared to cypermethrin 25EC. Emamectin benzoate 5SG @ 1 x 10-7 to 1 x 10-9 per cent concentrations recorded 100% mortality against 2nd instar larvae and LC50 values for 3rd instar larvae was 0.00000000045%. Insecticides novaluron 10EC, spinetoram 11.7EC and cypermethrin 25EC did not show promising and consistent results against 3rd instar larvae of H. armigera at 24 hrs. The LT50 of novaluron 10EC at 0.00005% concentration was 19.861 hrs and it was 28.144 hrs at 0.000001% against 2nd instar larvae of H. armigera
Higher Education has an important role in the task of rebuilding a nation and it paves the way for overall development of a nation. The twentieth century has witnessed several revolutions like Green revolution, White revolution, I.T revolution etc; transforming human civilization in to new heights. At the start of 21st century, there is a lot of importance given to higher education. Every country realizes the value of higher education and the benefits accrue from it. There is a greater importance attached to higher education. “The social demands for higher education continue to increase. Indian higher education has a rich and complex history that spans millennia. This abstract provides an overview of the key developments in Indian higher education, highlighting its evolution from ancient times to the modern era. The history of Indian higher education is marked by the establishment of ancient centers of learning, the influence of various empires and dynasties, colonialism, and post-independence reforms. This abstract also touches upon the challenges and opportunities that have shaped the landscape of higher education in India.The history of Indian higher education can be divided into several distinct periods. In ancient India, centers of learning such as Takshashila and Nalanda emerged as renowned seats of knowledge, attracting students and scholars from across the world. These institutions laid the foundation for a tradition of rigorous intellectual inquiry
The primary cause of many fatalities is hypertension (high blood pressure). Many hypertensive patients are not even aware that they have the condition. As a result, hypertension is sometimes referred to as a silent killer. Until the harmful effects of high blood pressure, such as myocardial infarction, stroke, renal abnormalities, and vision problems, are identified, hypertension is typically asymptomatic. Without the use of herbs and dietary control, conventional medication therapy could not be enough to treat hypertension. The growing number of persons with high blood pressure can be effectively treated using alternative medicine. Numerous alternative therapies, such as diet, exercise, stress management, vitamins, and herbs, have been proven to be effective in lowering high blood pressure. There are several medications available to treat this disorder however popular antihypertensive medications typically have a long list of adverse effects. Numerous active ingredients with pharmacological and preventative qualities found in medicinal plants can be used to treat hypertension. This review discusses an overview of important medicinal plants and phytochemicals with hypotensive or antihypertensive effects.
Mediterranean journal of pharmacy and pharmaceutical sciences
Background: Poverty and malnutrition are associated with the risk of developing tuberculosis (TB). Nutritional reintegration with anti-TB therapy may improve treatment success rate. Aim: To investigate the nutritional status of low-income pulmonary TB patients in relation to the different anti-TB treatment phases. Methods: Forty five pulmonary TB patients and 40 controls aged 19-54 years, receiving treatment at Infectious Disease Hospital, Calabar, Nigeria, between September 2018 and July 2019 were studied. Serum total protein, albumin, iron and vitamin A were determined by colorimetric and HPLC methods respectively. Height and weight were measured and BMI computed, and data analysed using Student’s t-test, ANOVA, and Pearson’s correlation at P<0 P=0.001).>0.05) respectively. Albumin and iron were significantly lower in CPAT-HIV compared with CPAT patients. Albumin correlated positively and significantly with iron (r=0.405, p=0.006) in TB patients. Conclusion: Tuberculosis is associated with decreased BMI, albumin, iron and vitamin A, and higher total protein, and globulin, suggesting that malnutrition may be associated with TB risk, poor treatment compliance and outcomes
This study evaluated power system reliability and frequency tolerance requirements for the management of critical-care medical devices at the Niger Delta University Teaching Hospital (NDUTH). The analysis focused on two primary parameters: voltage stability and frequency deviation, to determine the conditions necessary for sustaining Intensive Care Unit (ICU) ventilator uptime and neonatal incubator performance. Voltage and frequency data were collected at regular intervals over a five-month period and analyzed using reliability modeling and MATLAB-simulated multidimensional surface plots. Results indicated that ICU ventilator uptime stabilized at 96.1% when system voltage remained within the 208 and 222V band under controlled load conditions. Neonatal incubator reliability, however, declined sharply when frequency deviation exceeded 0.11Hz, activating maintenance thresholds. Extended voltage dips below 185V and frequency excursions above 0.12Hz were associated with increased likelihood of device failure and elevated corrective maintenance demand. The findings underscored that uninterrupted operation of critical-care devices depends on integrating voltage and frequency reliability metrics into equipment management protocols as conclusion. Accordingly, it was recommended that NDUTH management implement continuous power-quality monitoring, enforce maintenance protocols guided by operational thresholds, and strengthen redundancy measures. These actions will enhance device reliability, reduce service interruptions and support safer, more consistent delivery of critical care in the hospital setting
In this paper, an approach for formulation of generalized field data based model for cylinder head moulding operation. The aim of field data based modeling for cylinder head moulding operation is to improve the output by correcting or modifying the inputs. The goal of the research is to reduce human energy input required while performing cylinder head moulding operation. With the reduction in human energy input, automatically, the productivity of the process will also increase. The study identifies important ergonomic and other work environment related parameters which affect productivity. The identified parameters are properties of sand, physical dimensions of tools, energy outflow of workers, anthropometric data of the workers, working conditions like relative humidity, ambient temperature. Out of all the variables, responses and causes are identified. After dimensional analysis relationship between the dependent and independent parameters, a mathematical model is established having a relationship between output parameters and input. To get the optimized values model is optimized using the optimization technique. Sensitivity analysis is a tool which can be used to find out the effect of input one parameter over the other. The model will be useful for an industrialist to select optimized inputs so as to get targeted responses.
Introduction and importance: Human echinococcosis, also known as‘hydatid cyst,’ constitutes a zoonotic parasitic disease attributed to Echinococcus granulosus or Echinococcus multilocularis. Primary af ictions occur in the liver and lungs, whilst the implication of alternative organs remains infrequent. The clinical presentation can vary, and large cysts may cause compression symptoms and complications. This case involved a 21-year-old Palestinian female with three large hydatid cysts in the liver, causing compression of adjacent structures and unique clinical manifestations. Case presentation: A female aged 21 arrived with signs of heart palpitations, shortness of breath, tiredness, and pain in the right upper abdomen, alongside a background of infertility. During routine pre-IVF ultrasound, three liver hydatid cysts were unexpectedly found, leading to a referral to the surgical department. Laboratory tests and imaging con rmed this diagnosis. The surgery involved cyst aspiration, hypertonic saline injection, and marsupialization. Post-surgical complications were managed as they occurred. The symptoms lessened afterward, and a successful pregnancy was achieved 9 months post-surgery. Clinical discussion: Zoonotic infection by cystic echinococcosis (CE) primarily engages the liver and lungs. The progression of symptoms is contingent upon cyst placement and resultant pressure on adjacent tissues. Diagnosis requires imaging alongside serological assays, while large cysts necessitate surgical intervention. Conclusion: The presented case underscores the complexity of managing multiple extensive liver hydatid cysts, highlighting the necessity to consider hydatid disease amidst patients presenting with indeterminate symptoms, particularly within endemic zones. An extensive surgical strategy produced positive outcomes, illustrating the signi cance of prompt intervention for symptom alleviation and sustained patient health.
Background: To assess the awareness, knowledge about refractive errors and strabismus among the general public in southern Indian states of Andhra Pradesh and Telangana. Methods: A cross sectional population-based survey used a semi structured questionnaire on awareness, knowledge on refractive errors and strabismus done as part of knowledge, attitude and practices study (KAP). Stratified multistage cluster random sampling method was used with a sample size of 867 adults- ≥16 years. Having heard of refractive error and strabismus was defined as awareness and having knowledge of the type of error for which spectacles were worn, was considered as knowledge. A pilot study was conducted to validate the questions used in the main study. Statistical package SPSS (version 19) was used for analysis to calculate logistic regression and odds ratios for gender, age, education and urban-rural areas. Results: A total of 782/867 (90.1%) subjects participated in the survey with females 47.4%. 581 subjects (74.3%) were aware of refractive error. 690 subjects (88.2%) were aware of squint. With multiple logistic regression about awareness of refractive error to various variables, subjects who were educated 11th class to degree had a higher awareness (OR: 2.40; CI: 1.25-4.60). With multiple logistic regression about awareness of squint to various variables, females had a higher awareness of squint (OR: 1.98; CI: 1.19-3.31). Conclusions: Awareness of squint and refractive error was high among the general public, but the knowledge of it was limited.
Introduction: Augmented Reality (AR) technology is increasingly recognized for its potential to enhance various aspects of dental practice, including treatment planning, patient education, and training. Despite this potential, the understanding of dental professionals' knowledge, attitudes, and practices regarding AR technology remains underexplored. The objective of this research is to examine the experience, perceived advantages, and real application of augmented reality (AR) Technologies of dental faculty and students. Methodology: A sample of 132 dental students, some integrated into the workforce as part-time private dentists, and faculty members of a single dental school, completed a self-administered online survey. Knowledge and application of AR technology in dentistry, and Experience with AR practice, were the constructs of the study. An administered questionnaire, partially digital and partially paper and pencil, was divided into two parts: Knowledge Assessment and Practice Assessment. The survey results were analyzed using reference statistics. Results: Knowledge Assessment respondents confirmed understanding Augmented Reality (AR) technology (69.7), and AR technology in dental training/education was recognized (65.9). 57.6% of the participants in the Practice Assessment declared absence of AR in their educational and/or professional practice, but an AR technology practice was wanted (67.4). The self-rated proficiencies that 44.47% of the respondents professed were in the range of self-score 3 in the application of AR (moderate). A small fraction (16.7) declared their AR application self-score was above the higher order. Conclusion: It can be concluded from this work that AR technology in academic and practical dentistry is vastly underutilized, notwithstanding the high realization and appreciation for its application.
Background: Pulses are well known richest source of vegetable protein and is known as poor man’s food because of its essential component in diet. The frontline demonstrations of pulses were carried out on 311.8 ha area with 694 demonstrations in different clusters of Nagaur district of Rajasthan. Methods: Front line demonstrations on chickpea, mung bean and moth bean crop were conducted by Krishi Vigyan Kendra, Nagaur-I, Agriculture University, Jodhpur during rabi and Kharif season of 2011-12 to 2019-20. Result: In demonstrations up to 29.43%, 30.29% and 35.22% yield increase of chickpea, mungbean and moth bean crop was observed over the farmer’s practices in the year 2011-12, 2017 and 2016. The yield gap between improved technology and conventional farmer’s practices was ranging from 1.98 to 4.54 q/ha, 0.61 to 2.55 q/ha and 0.6 to 1.68 q/ha, respectively. Whereas, the highest net returns of ` 71,881 ha-1 , ` 45,884 ha-1 and ` 14,315 ha-1 was observed in the year 2019-20, 2014 and 2016, respectively with the highest incremental cost benefit ratio of 1:3.71, 1:3.95 and 1:1.97 under demonstrations practices.
The presented study initially attempted to discover bergenin as an antiemetic compound isolated from Peltophorum roxburghii L. leaves. It is the extension of antiemetic activity from the methanol extract of Peltophorum roxburghii L. leaves. The antiemetic activity was assessed using copper sulfate-induced emesis in the chick’s model. Bergenin (25 mg/kg, p.o.) exhibited significant antiemetic activity compared to the standard drug, chlorpromazine. This is the first time that bergenin has declared antiemetic activity. Bergenin has already been evaluated positively for its anti-inflammatory activity, and this paper will report its antiemetic activity. Both the activities of the same compound may be beneficial for drug design against the disease, as they have anti-inflammatory and antiemetic symptoms like migraines. The preliminary antiemetic evaluation of bergenin was conducted on a single dose due to the low yield of Bergenin. However, the result was significant in terms of the standard used. Further, the isolation and purification of Bergenin are in the process of establishing detailed data on different doses of Bergenin.
With the expansion of human societies, extending up to almost every corner of the earth, transforming it to be as per their condition, humankind has proved their extraordinary dominance on the earth. The dominating attitude of humans has not resulted pleasantly every time. Poverty is one such curse that has shamed the progressing world community. Christianity has dedicated a large portion of its ministerial approach towards the underprivileged. This paper presents a missiological approach to uplift the slum dwellers in the city of Pune with education and health reforms. A similar project was experimented in 2014 among homeless people. The project did well and the results were significantly progressive and potential. It is assumed that this paper will bring an insightful approach that benefits the slums in Pune and enhance the “serving the humanity” aspect of the Christian mission.
Elevated arterial blood pressure is the most important public health problem in developed countries. It often leads to lethal complications if left untreated. Brewer's yeast is celebrated for its various beneficial effects, including a possible hypotensive effect. Thus, the anti-hypertensive effects of brewer’s yeast were investigated. The hypertensive model was done by a once-weekly intraperitoneal injection of dexamethasone at a dose of 25 mg/kg combined with drinking a 1.0% sodium chloride solution containing 0.2% KCl and 2.0% glucose for six weeks. The blood pressure was measured by the rat carotid artery cannulation preparation. Different doses of brewer's yeast dissolved in distilled water were injected into the internal jugular vein, with measurement of blood pressure at each time. To explore the mechanism of the hypotensive effect of yeast, the yeast cardiac effect was verified by the use of isolated perfused rabbit heart preparations using different antagonists. It was found that dexamethasone elevated systolic blood pressure to 178.3±11.6 and diastolic blood pressure to 133.3±16.6 from normal levels of 115.0±9.1 for systolic and 74.0±4.1 for diastolic. The gradual increase in intravenous yeast doses ranging from 0.05 to 0.40 effectively lowered systolic and diastolic blood pressure in rats with normal pressure, bringing them to approximately 80.0±05.6 mmHg for systolic and 40.0±3.5 mmHg for diastolic. While doses exceeding 0.04 resulted in a drop in systolic pressure to 60.0±3.9 mmHg, diastolic pressure became unrecordable. The administration of the 0.20 dose resulted in unrecordable blood pressure. In hypertensive rats, a decrease in blood pressure was observed with doses ranging from 0.60-1.0 mg, leading to a reduction to 110.0±2.8 mmHg for systolic and 52.0±9.9 mmHg for diastolic pressures. Doses exceeding 1.0 mg further lowered systolic and diastolic pressures to 20.0±3.9 mmHg. There was a mild increase in heart rate with no change in cardiac force of contraction. This effect was not mediated through beta, calcium receptors, or the histamine effect. The findings show that the yeast has a dose-dependent blood pressure-lowering effect. The mechanism of the chronotropic effect is possibly due to its direct action.
Mediterranean journal of pharmacy and pharmaceutical sciences
Background and Aim: Ultrasound popliteal sciatic nerve block (UPSNB) is commonly performed in foot and ankle surgery. This study aims to assess the use of dexmedetomidine and dexamethasone as adjuvants in UPSNB for hallux valgus (HV) surgery, comparing their efficacy in producing motor and sensory block and controlling postoperative pain. The adverse event rate was also evaluated. Methods: This mono-centric retrospective study included 62 adult patients undergoing HV surgery: 30 patients received lidocaine 2% 200 mg, ropivacaine 0.5% 50 mg and dexamethasone 4 mg (Group 1), whereas 32 patients received lidocaine 2% 200 mg, ropivacaine 0.5% 50 mg, and dexmedetomidine 1 mcg/Kg (Group 2). At first, the visual analogue scale (VAS) was evaluated after 48 hours. The other outcomes were time to motor block regression, evaluation of the first analgesic drug intake, analgesic effect, adverse effects (hemodynamic disorders, postoperative nausea and vomiting (PONV)) and patient satisfaction. The continuous data were analyzed with student’s t-test and the continuous one with χ2. Statistical significance was set at a p-value lower than 0.05. Results: No significant difference was found in VAS after 48 hours (4.5 ± 1.6 vs 4.7 ± 1.7, p = 0.621) to motor block regression (18.9 ± 6.0 vs 18.7 ± 6, p = 0.922). The number of patients that took their first analgesic drug in the first 48 h (p = 0.947 at 6 hours; p = 0.421 at 12 hours; p = 0.122 at 24 hours and p = 0.333 at 48 hours) were not significant. A low and similar incidence of intraoperative hemodynamic disorders was recorded in both groups (hypotension p = 0.593; bradycardia p = 0.881). Neither PONV nor other complication was found. Patients in Group 1 reported a lower degree of interference with sleep (p = 0.001), less interference with daily activities (P = 0.002) and with the affective sphere (P = 0.015) along with a more satisfactory postoperative pain management (p < 0.001) as compared to Group 2. Conclusion: No significant differences were observed in the duration of motor and sensory blockade between patients in both groups. Additionally, both groups showed good pain control with a low rate of adverse effects, even if there was no clinical difference between the groups. However, patients who received dexamethasone reported experiencing less interference with their sleep, daily activities and overall emotional well-being, and overall pain control.
We reported a case of cyclophosphamide (CYP)-induced posterior reversible encephalopathy syndrome (PRES) in a 26-year-old previously healthy male patient who was presented to the emergency department with a history of fever, shortness of breath, and hemoptysis. After extensive investigations, including bronchoscopy and autoimmune screening, he was diagnosed with renalpulmonary syndrome. The diagnosis of CYP-related PRES was based on the development of neurological clinical picture supported by magnetic resonance imaging findings. The dose of CYP was decreased to 75 mg/day, and the patient’s symptoms improved after 3 days.
Banks need finance to carry out their day to day activities smoothly. There will be times where the borrowers fail to repay the money leading a risk to the lenders. There are various types of risks faced by the banks such as financial and non-financial risk in the unstable environment. These risks may be a threat for the existence and achievements of banks. A Credit risk is the risk which arises when the borrower fails to make required payments. It is a huge loss to the lender where he loses both the principal and interest which leads to the interruption of the cash flows and increase in collection costs. Banks usually follow a certain framework while lending loans so that they can manage the credit risks. The main purpose of credit risk management is to find out how much credit should be provided to the borrowers and the different ways to collect the amount back. The success of banks depends on the formulation of the policies and procedures of lending the loans and collecting the amount back and avoid Non-Performing Assets (NPA) to the banks. When banks collect their debts systematically and avoid the Non- Performing Assets (NPA), they can survive in the competitive market. The study is focused on the comparison of two banks such as Canara Bank and Karnataka Bank with regard to loans, advances, interest received and expended and the variation in the levels of Non- Performing Assets. Methodology used is the secondary source of data where the balance sheet of the banks and the income and expenditure statement of the banks are being used to explore the credibility and the capacity of the banks in managing the credit risk.
Background: Although geriatric depression is widespread in primary health care (PHC), local studies on the prevalence of depression in elderly PHC patients appear to be scarce. This study aimed to determine the prevalence of depressive symptoms and some of the associated risk factors among elderly PHC patients. Methods: A cross-sectional study recruiting elderly people (60 years or older) from five PHC centers in Port Said Governorate was conducted. All participants had a structured interview. The long version of the geriatric depression Scale (cut-off point ≥10) was used in elders with a Mini-Mental State Examination ≥24. Results: About two-thirds of the total sample (65.7%) was female. The total prevalence of depressive symptoms was 49.4% of all subjects, more commonly in women (58.1% vs. 32.8%). Multiple regression analysis shows that female gender, high education, unemployment, low income, lonely life, loss of a close person, chronic diseases, tumor, iatrogenic medications, and depression history were the significant associated risk factors of depression in the studied elders after adjusting all previous variables in addition to age and marital status. Conclusion: Depressive symptoms constitute a significant health problem among older PHC patients in the Port Said governorate. Routine screening for depression of every elderly PHC patient is recommended for early detection.