Arenaria serpyllifolia L. is a medicinally important plant found in subtropical and temperate regions of the Himalayas from Nepal to Kashmir. The plant is used traditionally to treat kidney and bladder-related problems. Flavonoids and xanthone-containing compounds, such as epicatechin, japonicumone, quercetin, etc, are reported in the plants. Plants have shown Inhibitory effects on Carboxyl esterase

Dr. salman ahmed

Hypothyroidism is a common endocrine disorder resulting from deficiency of thyroid hormone or its effects on peripheral tissues. Previous hospital based study have revealed high prevalence of hypothyroidism in pregnant women. Also, studies with small sample size indicated a rising trend of prevalence of hypothyroidism during pregnancy. Moreover, pregnancy is seen as a risk factor in the occurrence of thyroid dysfunctions. Thus, the aim of was to assess and analyze prevalence of hypothyroidism among Libyan pregnant women in Benghazi city in to study its relation and risk in pregnancy. The study was conducted on a sample size of 177 Libyan pregnant women in Benghazi city in Libya during 2018. A cross-sectional observational study was conducted in clinics located in Benghazi city. Responses to the question was coded and analyzed. The prevalence of hypothyroidism among the pregnant women was found to be 10.2% (n = 18) and no significant relation between age and hypothyroidism among women. Only nine percent of the pregnant women had medical conditions (as diabetes mellitus and high blood pressure). 28% of the hypothyroidism pregnant women are of the first gestation and 72% are of the second or more. 83% of the hypothyroidism pregnant women had no thyroidectomy. Thus, this study concludes that there is a high prevalence of hypothyroidism during pregnancy period in Benghazi and a national screening is necessary for hypothyroidism in Libya.

Mediterranean journal of pharmacy and pharmaceutical sciences

Étudier les phénomènes grammaticaux actuels sans s’interroger sur la longue trajectoire historique qui a servi de support et de canal au français moderne manquerait de pertinence. En effet, une telle étude permet une meilleure compréhension des phénomènes linguistiques contemporains. Ainsi, notre domaine de recherche, la linguistique diachronique, met l’accent sur les connaissances étymologiques de la langue. Il s’agira, pour les besoins de l’article, de rendre compte de l’évolution morphologique du présent de l’indicatif depuis le latin jusqu’au français moderne. Notre curiosité nous poussera à nous interroger sur les raisons qui expliquent l’écart morphologique du présent de l’indicatif entre le latin et le français moderne. En sus, l’étude des variations diachroniques du présent de l’indicatif renseigne sur les formes actuelles de ce temps verbal. Du latin au français moderne, le présent de l’indicatif subit des flottements aussi bien dans ses radicaux que dans ses désinences. Ceci met en chef l’écart formel existant entre le présent latin et celui du français actuel. Toutefois, les phonèmes subirent des transformations selon qu’ils étaient toniques ou atones, radicaux ou désinentiels. Certaines formes se sont maintenues avec modification ou non de sons; d’autres ont complètement disparues du système. Suivant un ordre chronologique et des lois phonétiques cohérentes, nous montrerons que les formes actuelles du temps le plus usuel du système, le présent, ne sont pas le fruit du hasard. De ce fait, la langue moderne gagnerait à revisiter la morphologie des temps verbaux depuis leur origine pour mieux asseoir les difficultés liées à la conjugaison et fournir une explication authentique sur les variations de forme jusque-là ignorées par certains.

Assanvo

Emesis encompasses the forceful expulsion of the stomach's contents via the mouth or sometimes the nose. The adverse effects of currently available anti-emetic agents potentiate the natural product researchers to explore natural anti-emetics with fewer side effects. The presented communication reviews the anti-emetic effect of two hundred and forty-five plants belonging to seventy-eight families in different parts of the world. It also outlined the anti-emetic effect of plant extracts and isolated secondary metabolites studied through a variety of animal models of emesis. The reported anti-emetic plants in different countries and cultures and the scientific studies on extracts may help in the identification of promising single chemical compound(s) that may be used as potential leads for developing safe anti-emetic agents in future. Moreover, the reported secondary metabolites having the same effect may open the door for the search for the same secondary metabolites from other natural sources. This review will provide useful information for discovering natural anti-emetic compounds and fill the gaps in knowledge.

Dr. salman ahmed

It is virtually impossible to mention the phrase ‘project management’ without introducing the concept of risk management. As Hillson (2016, p.11) states, “risks [are] particularly relevant to projects” suggesting that effective management of risk is an integral ingredient for project success. The close link that exists between projects and risks may be deduced by the definition of the word ‘project’. In simple terms, projects refer to unique endeavours undertaken with the aim of achieving desired outcomes. These endeavours typically specific start and completion dates, and involve resource, time and cost constraints. These characteristics imply that projects are intended to deliver identifiable benefits to the organisation; these benefits, however, are not enjoyed immediately even if the project is completed. On the contrary, projects commonly create capabilities that call for operation or utilisation for the actual gains to be generated (Hillson, 2016 p.11). The interpretation of this is that projects have a risk element in that they contain a potential reward and possibility of loss. For this reason, project managers must be well-versed with risk management.

Mohamed sorogy

A new feature generates customer delight by using modern computer vision techniques to drive new search paradigms through visual discovery.

Senthilkumar gopal

The present study aims to shed some light on the gains from consolidation exercise in terms of profitability of banks. Through the application of paired t-test, we arrived at the result that the consolidation of banks did improve the profitability of banks in India. The increase in profitability of banks under study is due to an increase in employee turnover and the subsequent reduction in operating expenses. Merger and acquisition programmes in Indian banks cannot be regarded as a false step if the benefits of it accrue to all stakeholders.

Akhil antony

Dietary intake of contaminated food with heavy metals may cause severe risk for the human health. Heavy metals affect adversely a human health. The current study assessed the concentrations of heavy metals including Cu, Zn, Pb and Ni in eggplant (Solanum melongena L.) of urban and rural areas in Bangladesh. The experimental samples of fresh eggplant fruits were collected from six local markets in Jashore, Bangladesh, and the tissues were extracted with nitric acid and hydrogen peroxide. Trace elements in eggplant fruits were estimated with atomic absorption spectrophotometer. Obtained result show that Heavy metal concentrations were high in the urban areas compared to rural areas. Heavy metals in the eggplant fruits of rural and urban areas were: Pb (2.74-18.64), Cu (10.20-67.16), Ni (46.63-148.46), and Zn (86.65-148.73) mg.kg-1 respectively. The concentrations of Pb, Ni and Zn in eggplant were at an excess of safe limits according to the Food and Agriculture and World Health Organizations. While, Cu was lower than the maximum safe limit. The present study concluded that growing eggplants in Jashore areas are heavily contaminated with Pb, Ni and Zn that would be hazardous for consumer’s health. The result of this study will be beneficial for the agricultural policy makers in Bangladesh to take appropriate action and reduce the heavy metal toxicity among fresh food products.

Arafat hassan razon

Investigating school performance and competencies, especially on leadership, received a considerable attention in the past. In fact, there have been multitudes of evidence that leadership can impact school performance, student achievement, or outcome. Also, there was no single measurement of school performance. This study examined the influence of leadership and core behavioral competencies on the school performance of school heads. This was to build a new model of school performance. Using an explanatory research design, it administered a survey questionnaire to 192 randomly chosen school heads from the 37 districts of Department of Education Division of Surigao del Sur. Also, it used data mining for the performance ratings of school heads from the division office. Regression analysis tested three hypothesized models of school performance where leadership and core behavior competencies serve as independent variables. Results showed that leading people was a significant predictor of school performance. Thus, leading people can best explain the school improvement as a proposed model. The results have implications for future research, leadership practice, and theoretical development of school performance model among school heads.

Manuel caingcoy

This study aims to investigate the relationship between green marketing elements and customer purchase intention. To conceptualize green marketing, the researcher has researched the literature and identified the green marketing elements which include Green products, Green price, Green place, Green promotion, and Green Distribution. By using the snowball sampling technique, questionnaires from the respondents were collected as part of the study's survey methodology. According to the study's findings, there is a clear, substantial correlation between customer purchase intention and Green marketing.

Santhosh sandy

This work was focused on identification and evaluation of process parameters of modified nanoprecipitation method, for fabrication of lomustine nanoparticles, with the aim of reducing cancer cell viability at low concentration of lomustine. The parameters controlling particle size, mostly in nanosize, were solvent/nonsolvent composition and emulsification speed of homogenizer along with aqueous phase volume. This controlled particle size is below 250 nm. The stabilizer concentration controlled particle size is within 68 nm ± 0.89 to 137 ± 0.94 nm with PDI 0.06 ± 0.008 to 0.25 ± 0.001. But, the stabilizer addition mode showed more uniform size distribution with PDI 0.085 ± 0.004. Entrapment efficiency was maintained well above 47 ± 0.23%. The drug release pattern was monophasic with controlled release over 24 hrs. In the method used, drug content was affected by ratio of polymer to drug to organic solvent, as well as homogenization speed and time. Percentage viable cells of L132 human lung cancer cell line remained, were only 5% at 100 μg/ml lomustine equivalent PLA nanoparticles.

Archana mehrotra

Kepatuhan terhadap terapi farmakologi merupakan kunci utama pengobatan penyakit diabetes, tetapi belum mendapat perhatian penuh oleh para klinisi. Beberapa systematic review faktor kepatuhan telah dilakukan di beberapa kawasan negara. Namun, tidak menampilkan studi dari Indonesia. Penelitian ini bertujuan untuk meninjau secara sistematis faktor-faktor yang dapat memengaruhi kepatuhan minum obat diabetes melitus (DM) di Indonesia. Systematic literature review dilakukan melalui pencarian pada database jurnal Nasional (Garuda dan Sinta) dan Internasional (PubMed dan Science Direct). Penelitian yang sesuai dengan kriteria inklusi dan dipublikasikan pada Januari 2011 – Desember 2020. Kualitas penelitian dinilai menggunakan panduan SQAT. Metode pelaporan penelitian menggunakan pedoman PRISMA. Faktor kepatuhan diklasifikasikan berdasarkan domain faktor kepatuhan menurut World Health Organization (WHO). Sebanyak 370 artikel ilmiah penelitian dari database Garuda (n=36); Science Direct (n= 108); PubMed (n= 18); Sinta (n= 208). 341 artikel penelitian dieksklusi, 29 artikel skrining full text, dan 16 artikel penelitian memenuhi kriteria inklusi untuk dianalisis. Faktor yang memengaruhi kepatuhan minum obat diabetes adalah faktor sosial dan ekonomi (penghasilan, tingkat pendidikan, dan pekerjaan), faktor tenaga dan sistem kesehatan (tenaga kesehatan), faktor terapi pasien (jumlah obat diabetes, frekuensi minum obat, dan produk obat), faktor penyakit pasien (kadar gula darah, durasi penyakit), faktor pasien (jenis kelamin, faktor emosional, dukungan sosial, tingkat pengetahuan, dan kepuasan pengobatan), dan faktor pengelolaan penyakit (konseling dan edukasi farmasi). Faktor yang memengaruhi kepatuhan minum obat DM di Indonesia sangat beragam, dan multi faktor. Faktor tersebut dapat berfungsi sebagai target intervensi yang relevan. Para klinisi perlu mempertimbangkan penyesuaian frekuensi minum obat dan pemberian dukungan sosial kepada pasien DM.

Much ilham novalisa aji wibowo

Use of chemical fungicide to control plant diseases causes several adverse effects such as, development of resistance in the pathogen, residual toxicity, pollution to the environment etc. So an alternative way to overcome the usage of dreadful chemicals is very important. The use of plant extracts as biofungicide is one of the popular and effective method. Araucaria columnaris is a commonly seen ornamental plant known as Christmas tree. It’s a South African species, under the family Araucariaceae. Hence, in the present study, the plant resin extract was tested in-vitro against major plant pathogensby preliminary bioassay. It was found that up to 95% reduction of mycelium growth was observed against major phytopathogens such as Fusarium oxysporyum, Rhizoctoniasp, Cylindrocladiumsp, Alternariasp, and Colletrotricum sp., causing tomato wilt, damping off, foliage blight, and leaf blight diseases in economically important plants. Up to our knowledge it is the first report showing the antifungal activity of Araucaria columnaris resin as antifungal agent. By using this valuable tree, further work will be done to formulate commercial biofungicide.

Dr. saranya devi k

Venous thromboembolism (VTE) is a serious medical condition that has a high clinical burden on both the mother and fetus, despite having a low incidence during pregnancy and the postpartum period. VTE is a leading cause of death among pregnant women and new mothers worldwide, and its severity cannot be underestimated. The development of VTE is influenced by a combination of genetic and environmental factors, as well as acquired conditions. Pregnancy-related changes, such as increased levels of coagulation factors and diminished fibrinolysis, can increase the risk of VTE. Additionally, older mothers, those who are obese, multiparous, or have undergone cesarean delivery, are at a higher risk of developing VTE. Owing to the lack of standardized guidelines and reliable data on VTE prevention, diagnosis, and treatment, authorities have developed risk scores that allow for a personalized assessment of the risk of thrombosis during pregnancy and postpartum, enabling a tailored approach to prevent thrombosis. Managing VTE during pregnancy poses significant challenges because the benefits and risks of anticoagulant treatment for both the mother and fetus must be carefully balanced. An interdisciplinary approach that includes obstetricians, neonatologists, physicians, and hematologists is essential to achieving optimal outcomes. This review explored the VTE updates in pathogenesis, presentation, complications, treatment options, and research gaps with proposal strategies to improve VTE outcomes and suggest further research.

Karishma

Epilepsy is a chronic neurologic disease that comes third after cerebrovascular and Alzheimer’s disease. Anti-epileptic drugs may affect certain hematological parameters of epileptic patients. Few researches investigated hematological adverse effects of antiepileptic drugs in Libya. Thus, the aim was to evaluate hematological parameters in epileptic children who are on antiepileptic drugs. This retrospective study included 83 pediatric patients with epilepsy recruited from Benghazi Children Hospital, Department of Neurology, from December 2017 to April 2018. Data collected included demographic characteristics, types of epilepsy, anti-epileptic drugs and serum hematological parameters. Hematological parameters recorded included: hemoglobin, hematocrit, platelet, mean cell volume, mean cell hemoglobin, mean cell hemoglobin concentration and white blood cell count. In all treated patients, regardless of the number of antiepileptic drugs therapy used, the average levels of hematological parameters were significantly lower in treated group compared to control group (11.64 gm per dl, 34.53%, 27.74 pg and 33.13 gm per dl, respectively). A significant increase (12.12109 per l) in white blood cell counts in treated group was found. Average hemoglobin, hematocrit and mean cell hemoglobin concentration levels were significantly lower in patients on poly-therapy compared to mono-therapy and control groups. Average white blood cell counts were significantly increased in patients on anti-epileptic drugs. In sodium valproate users, levels of hematological parameters were significantly decreased but significantly increased in white blood cell counts. In diazepam users, significant increases in white blood cells and platelet but no difference in other parameters observed. There were no differences in all hematological parameters among patients using carbamazepine except for platelet counts (significantly decreased). In conclusion, there is substantial effect of the anti-epileptic drugs, especially sodium valproate, on hematological parameters of children despite the effects were not critical as the changes were still in the normal range.

Mediterranean journal of pharmacy and pharmaceutical sciences

Hypertriglyceridemia-induced acute-pancreatitis (HTG-AP) is an important etiology of acute pancreatitis (AP). The treatment includes general management of AP with bowel rest, analgesia, and venous thromboembolism prophylaxis. Specific treatment of HTG-AP focuses on reducing serum triglyceride (TG) levels. Various modalities have been used, including heparin infusion, insulin infusion, plasmapheresis, and double filtration plasmapheresis (DFPP). However, the extent to which TG reduction translates into a clinical response remains unclear. This review highlights the emerging evidence on the management of HTG-AP. Insulin therapy and plasmapheresis remain treatment options to reduce TG. DFPP is an emerging treatment modality to reduce TG levels in patients with AP. However, to what extent this translates into a better clinical response is yet to be answered in large and prospective study designs.

Karishma

Covid 19, the pandemic originated in the Chinese city of Wuhan, had the entire world conquered. The structure and transmission of the causative organism, Coronavirus is well studied. Remdesivir, the product of Gilead pharmaceuticals, was effective against many viral infections, including Ebola and SARS. It comes under the category of nucleoside prodrug and has given promising results in the early trials against SARS COV 19. In depth, research is taking place at a rapid pace, so that Remdesivir will be available to the therapeutic community as an effective remedy for the pandemic caused by SARS COV2. If this meets success, the darkest era in the modern history of mankind may become a memory in the near future.

Vinod b

Abstract- The role of support vector machine in the evaluation of English teaching effect is very important, but there is a problem of inaccurate evaluation of results. The traditional English teaching mode cannot solve the accuracy and efficiency of the effect evaluation of students' English teaching and cannot meet the requirements of English teaching effect evaluation. Therefore, this paper proposes a neural network algorithm to innovate and optimize the analysis of support vector machines. Firstly, the relevant theories are used to construct a multi-index English teaching effect evaluation system with teachers and students as the main body, and the indicators are divided according to the data requirements of English teaching effect evaluation indicators to reduce the support vector machine in the interfering factor. Then, the neural network algorithm is used to solve the optimal solution of kernel function parameters and regularization parameters of the support vector machine, and the support vector machine scheme is formed, and the support vector machine results are carried out Comprehensive analysis. MATLAB simulation shows that the evaluation accuracy of the English teaching effect of the neural network algorithm and the support vector machine under certain evaluation criteria Optimal, short evaluation time.

Lokesh n s

Recently, the definition of cardiorenal syndrome (CRS), a condition with a complicated pathogenesis, has been revised. Logically, CRS syndrome should be classified according to the initial organ that is injured, resulting in damage to another organ. Hence, there are only three main categories of CRS. Category one includes acute and chronic CRS. Category two involves renal-cardiac syndrome (RCS), which can be classified as acute or chronic. The third category represents secondary CRS, referred to as cardio-reno-cardiac syndrome (CRCS), which can be subdivided into acute and chronic CRCS. In this part of our series, we will discuss the epidemiology, pathophysiology, diagnosis, treatment, and prevention of acute CRS. We retrieved articles published on acute CRS using different keywords and phrases between January 2019 and June 2025 to achieve these goals.

Karishma

Les études sur la langue française la présente souvent dans des situations où elle est en contact avec les langues africaines. Elle co-apparait avec les langues africaines dans les discours romanesques. Cette co-apparition n’est pas sans conséquences pour les deux langues en contact. Certains linguistes, surtout les sociolinguistes et les didacticiens, parlent d’insécurité linguistique. Ils la lient à toutes les situations linguistiques où deux langues entrent en contact. Ngamassu (2007, p.94) dit dans ce sens que « toute situation de contact des langues est source d’insécurité linguistique, car aucun locuteur/scripteur ne peut maîtriser toutes les variétés ou niveaux d’une langue ». Cette affirmation restreint l’insécurité au locuteur ou au scripteur. Les linguistes ignorent souvent l’impact négatif du contact des langues et s’intéressent à ses conséquences positives. Cet article a porté sur les manifestations de l’insécurité linguistique dans la prose romanesque de Kourouma et Badaman. Il a permis de voir que l’usage des langues maternelles dans le français constituait une menace de disparition et d’abâtardissement de la langue française.

Assanvo