Air pollution is a major health problem in developing countries and has adverse effects on human health and the environment. Non-thermal plasma is an effective air pollution treatment technology. In this research, the performance of a dielectric barrier discharge (DBD) plasma reactor packed with glass and ceramic pellets was evaluated in the removal of SO2 as a major air pollutant from air in ambient temperature. The response surface methodology was used to evaluate the effect of three key parameters (concentration of gas, gas flow rate, and voltage) as well as their simultaneous effects and interactions on the SO2 removal process. Reduced cubic models were derived to predict the SO2 removal efficiency (RE) and energy yield (EY). Analysis of variance results showed that the packed-bed reactors (PBRs) studied were more energy efficient and had a high SO2 RE which was at least four times more than that of the non-packed reactor. Moreover, the results showed that the performance of ceramic pellets was better than that of glass pellets in PBRs. This may be due to the porous surface of ceramic pellets which allows the formation of microdischarges in the fine cavities of a porous surface when placed in a plasma discharge zone. The maximum SO2 RE and EY were obtained at 94% and 0.81 g kWh−1, respectively under the optimal conditions of a concentration of gas of 750 ppm, a gas flow rate of 2 l min−1, and a voltage of 18 kV, which were achieved by the DBD plasma packed with ceramic pellets. Finally, the results of the model's predictions and the experiments showed good agreement.
Background: Cancer is the word used for a tumor that spreads & destroys the host and is one of the leading causes of morbidity and mortality in developed and developing countries. Good nutrition is important for good health. Methods: Non-experimental descriptive research design was adopted for a study to assess knowledge on meeting nutritional needs among 100 oncology patients receiving chemotherapy at Bhagwan Mahaveer Cancer Hospital & Research Centre, Jaipur. Sample selection using a non-probability convenient sampling technique. Data were collected through a self-developed structured knowledge questionnaire. Results: Our results revealed that the majority of cancer patients, 43%, were in the age group of 31-40 years, 39% had no formal education, 32% had secondary education, and 17% had primary education. 76% were males, 24% were female, and 87% of participants did not have a family history of cancer. 55.23% of patients reported that nurses did counselling. The majority (67%) of respondents reported that they had previous information on meeting nutritional needs through diet counselling, and 33% reported they didn’t have any information about meeting nutritional needs. Most (45%) of cancer patients had poor knowledge, 26% had average knowledge, and 29% had good knowledge scoring. Conclusion:Conclusion:Conclusion:Conclusion:Conclusion:Conclusion:Conclusion:Conclusion:Conclusion:Conclusion:Conclusion: We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most 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However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. 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However, the researcher developed an information booklet, and he hopes that the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy .
This review shares historical glimpses of the art and science of urinary crystal growth in the gel. This successful journey of long and detailed research consists of theoretical and experimental knowledge. The survey consists of historical aspects of crystal growth, the development of urinary crystal growth in the gel as an in vitro urolithiasis model and the application of this model to evaluate prophylactic management against kidney stones.
During the last few years, the pharmacy profession has expand significantly in terms of professional services delivery and now has been recognized as an important profession in the multidisciplinary provision of health care. The paper highlights the current scenario The Pharmacy profession in health care system. Pharmacist is a backbone that strengthens to health care system. Different roles of Pharmacist in different sectors of pharmacy profession like Industrial, academic s, community health, clinical research, drug design and discovery, developing NDDS etc. In nutshell pharmacist play an integral part of health care system. “Physician gives medicine to the patients but life to medicine given by pharmacist”
Clinical microbiology serves as a partner to clinicians in the diagnosis and treatment of infectious diseases. Antibiotics are prescribed empirically before the availability of antimicrobial susceptibility testing data, especially when the patient's medical status could deteriorate by suspending the treatment. To investigate the impact of antimicrobial susceptibility testing on the management of outpatients with suspected bacterial infection in Libyan patients, a cross-sectional prospective study concluded on microbial microdroplet culture by including outpatients with suspected bacterial infection, who have done antimicrobial susceptibility testing. Thus, 53 Libyan patients with urinary tract infections and 14 Libyan patients with skin infections were included in this study. Before the availability of antimicrobial susceptibility testing data, 25 patients were appropriately treated while 42 patients were inappropriately treated. After the availability of antimicrobial susceptibility testing data, the number of appropriately treated patients increased to 57 patients. Thus, antimicrobial susceptibility testing improved the management of 41 patients by discontinuing an unnecessary antibiotic in four patients, starting necessary antibiotic therapy in 18 patients, and changing to more appropriate antibiotic in 19 patients. However, the antimicrobial susceptibility testing has no impact on the management of 24 patients and has led to the worsening of the management of two patients. The effect of antimicrobial susceptibility testing of antibiotic de-escalation was assessed in 35 patients; however, antibiotic de-escalation occurred in six patients. Thus, data of antimicrobial susceptibility testing has improved the management of Libyan outpatients with bacterial infection but their role in antibiotic de-escalation was slight
Mediterranean journal of pharmacy and pharmaceutical sciences
The inclusion of hydroelectric power is crucial to Nigeria's overall energy mix, playing a significant role in electricity generation. However, the Shiroro hydro plant, one of the main facilities located on the Kaduna River, is currently facing operational obstacles due to deteriorating infrastructure and inadequate maintenance practices. To overcome these challenges and improve efficiency within Nigeria's hydroelectric power sector, a hybrid-optimization approach has been proposed. This study sought to enhance the efficiency of the Shiroro hydro plant by implementing this innovative method. To achieve our objectives and address pertinent research questions, a mixed research method combining primary and secondary data was employed. The analysis included hydropower modeling and hydro-turbine input-output modeling. Three optimizer models, namely the particle swarm optimizer (PSO), Ant colony optimizer (ACO), and Artificial bee colony optimizer (ABCO), were utilized to formulate objective functions and task representations. The study involved comparing the daily output and fitness response of the Shiroro hydro plant through swarm optimizer iterations. The findings revealed a clear correlation between the turbine's power output and the water flow rate and water column height, suggesting that altering these factors could significantly improve the plant's performance. The comparison of the PSO, ACO, and ABCO models demonstrated that PSO and ABCO generated optimal or near-optimal solutions, while ACO produced suboptimal results. Consequently, the study concluded that enhancing the Shiroro hydro plant's output was feasible by increasing the water flow rate and column height. Additionally, the utilization of PSO and ABCO models proved to be an effective means of accurately predicting the turbine's output. As a result, the study recommended the integration of hybrid optimization techniques to monitor and identify any deviations in the Shiroro hydro plant's daily power output. This approach would enable prompt maintenance to be carried out, preventing significant damage to the plant. Ultimately, this research contributes valuable insights into improving the efficiency and performance of Nigeria's Shiroro hydro plant.
The Fourth Industrial Revolution (4IR), internet definition is considered as growing out of the third industrial revolution, but is considered a new era rather than a continuation because of the explosiveness of its development and the disruptiveness of its technologies. It is not a new phenomenon that many South African manufacturers are facing important talent challenges when organising their business. Diverse IT skill sets, improved skills blend and a rearrangement of skills are necessary. It is undisputed that 4IR requires a highly skilled workforce, and one which South Africa, regrettably, has been struggling to produce. It was the purpose of the study to gain an understanding of what Essential Employee Knowledge Management and Re-Skilling is needed in the South African Automotive Industry towards 2030 with regards to the Fourth Industrial Revolution (4IR). Methodology: Firstly, an environmental scanning was performed, examining pertinent literature, thereafter a case study approach was used was used to describe the true experiences of assembly workers and their immediate supervisors in a South African automotive plant. Results: The automotive industry is extremely robust and skilled employees are essential. From the study, the major solution to remedy low competence was continuous skills transfer through highly structured cross-functional skill development programmes. Conclusion: The study results cannot be generalised but do give an insight into what the current situation is in an automotive industry in South Africa.
This study was aimed to develop lomustine loaded chitosan nanoparticles using a homogenization and spray drying technique. Effect of crosslinking agents (sodium tripolyphosphate (TPP), and sodium hexametaphosphate (HMP)) were studied on the leaching of drug, water uptake of hydrogels, drug release from matrix and its mechanism. Nanoparticles were obtained in the average size range of 111±16.2 to 942±11.7 nm with polydispersity index (PDI) from 0.116±0.039 to 0.517±0.037. Zeta potential of nanoparticles was ranged from 29.0±1.1 to 56.0±1.1 mV. The % encapsulation effi ciency of nanoparticles ranged between 58±0.88% and 96±0.51%.nanoparticles were coated with PEG 6000 to modulate drug release. Swelling index of chitosan-TPP and chitosan-TPP-PEG nanoparticles was about 428% and 350% over the 4 h and it was more (about 465% and 395%) for chitosan-HMP and chitosan-HMP-PEG nanoparticles. Drug release was sustained and diffusion controlled. Optimized formulation was tested for anticancer activity and drug retention study. Cytotoxicity on human lung cancer cell line L132 was studied by trypan blue dye exclusion test. Drug loaded nanoparticles killed L132 cells more effi ciently than the corresponding drug alone (p< 0.05). Due to the increased surface area lomustine loaded TPP and HMP crosslinked chitosan nanoparticles showed better anticancer activity.
Industry 5.0 is still a developing concept, but it is expected to leverage a range of advanced technologies to facilitate human-machine collaboration and enable more customized and sustainable manufacturing.This research paper tried to discuss the opportunities and challenges in the implementation of Industry 5.0. It primarily explored the need to transform from Industry 4.0 to Industry 5.0. The research paper further studied the technologies needed for the implementation on Industry 5.0 and also the principles of Industry 5.0.
Introduction: Mental illness is a global issue that affects various population groups, including university students. Gaining insights into students' perspectives on mental illness plays a vital role in fostering mental health awareness and combating stigma in educational environments Purpose: The present study aimed to investigate Vietnamese undergraduate students’ knowledge, perceptions, and attitudes of mental illness by focusing on the dimensions: (i) the level of knowledge students possess about the causes and manifestations of mental illness, and (ii) their attitudes towards individuals experiencing mental health problems. Methodology: Using a descriptive cross-sectional design, this study involved 350 undergraduate students from five universities in Ho Chi Minh City, Vietnam. Data collection was conducted between June and July 2024 and utilized the Perception Towards Persons with Mental Illness (PWMI) Scale adapted from previous studies. Data analysis was performed using the Statistical Package for Social Science software, version 25 (IBM SPSS, Chicago, IL, USA). Results: The results indicated that approximately 80.6% knew about mental illness, and 70.5% perceived mental illness as a common or quite common phenomenon in Vietnam. Regarding the etiology of mental illness, a significant majority identified "bad things happening to you" as a cause (73.3%), followed by substance abuse (51.4%) and brain disease (50.0%). The findings also revealed that, despite some positive perceptions and attitudes, many responses clustered around the neutral option, particularly for controversial or personal items. Conclusions: The findings of this study underscore the need for targeted educational interventions to foster more informed and compassionate attitudes towards individuals with mental illness among undergraduate students.
Abstract In the existing investigation, experiments were carried out to assess the F2 population’s resultant of crosses between improved Basmati 370 and MAS25 for various agronomical and root traits cultivated under aerobic water conditions. Large variations for grain yield, root length, root dry biomass, root thickness and length/breadth ratio of grain have been displayed in segregating F2 populations. A close examination of phenotypic correlation exhibited that in the F2 population, root length was certainly matched up (r = 0.496) with root thickness. A DNA fingerprinting catalog for the currently studied F2 generation was arranged using 61 polymorphic SSR markers. Composite Interval Mapping (CIM) inspection with WinQTL cartographer version 2.5 disclosed 13 putative QTL (Quantitative Trait Loci), out of which 6 QTL were for root characters 7 QTL for agronomical characters situated on 1, 2, 3, 8 and 10 chromosomes. The QTL documented in the above-said generation, some promising F2 plants were also scrutinized and found in the homozygous or heterozygous state with high repetitions.
Patients who are on regular hemodialysis and who have advanced renal failure but have not yet started on renal replacement therapy have a high risk of tendon rupture, although this is a rare situation. We reported a case of 55-year-old male patient who had been on regular hemodialysis for the past 10 years. He presented with a sudden onset of pain and swelling in the left posterior ankle while climbing stairs. Ultrasonography revealed a complete disruption of the Achilles tendon, which was surgically repaired. His medical history was remarkable for the right Achilles tendon rupture a year ago. Investigations revealed tertiary hyperparathyroidism with chronic metabolic acidosis and high β-2 macroglobulin. With surgical repair, physiotherapy, and parathyroidectomy, the patient regained full active mobility. This case emphasized the importance of high parathyroid hormone level, metabolic acidosis, and high β-2 macroglobulin in the pathogenesis of tendons ruptures.
Small, medium and micro enterprises (SMMEs) represent a vital element in our economy in terms of addressing unemployment and the gross domestic product (GDP) of our country. Improving the success rate of SMMEs would save a lot of financial resources, thus understanding the financing options that complement success at different phases of the business is very important. This research sought to examine the extent to which the financing options chosen by entrepreneurs will have an impact on business success. The investigators adopted the progression of the ventures along the business life cycle stages as a benchmark for assessing success. The study focused primarily on SMMEs in the Eastern Cape Information Communication Technologies (ICT) sector. Data was obtained using an online survey which reached 50 small business owners/ business representative within the ICT sector in the Eastern Cape Province. The research study showed the role that internal financing options, such as personal savings, family, relatives and friends' financing, retained earnings, sale of existing assets and cutting down stock levels, play in the achievement of ICT SMME success. Moreover, examined external financing options such as Broad-Based Black Economic empowerment (B-BBEE) financing, bank loans, equity financing, government grants, trade credit, to SMME success. Key results revealed that the financial support of B-BBEE and personal savings have played a key role in the success of ICT SMMEs throughout the business life cycle phases. This occurs after an ICT SMME has advanced successfully over the start-up stage and aims for success in the development phase. The finding revealed that for these SMMEs to attain success at the development stage, they should finance their business investment projects utilising credit trade, bank loans, families, relatives and friends. The abovementioned financing options are only substantially linked to good advancement from the development phase onto the expansion phase. Also, suggestions have been made to the ICT SMME management to include B-BBEE finance, personal savings, bank loans, families, relatives and friends and trade credit as suitable funding choices for the ICT SMME's life cycle
Natural products, the most significant source for pharmaceutical development, have been investigated and utilized to alleviate diseases since early human history. The currently accepted modern medicine from different natural products has gradually developed over the years and is God's gift in the sense of traditional knowledge. Trustful humanity believes that drugs can cure every ill of natural origin. Natural medicines, prevalent in holy books, folklores, Materia medica and other historical literature, have become an essential domain of modern pharmaceutical sciences. Natural compounds from terrestrial and marine organisms have been extensively used to treat many diseases in their natural form or as a template for synthetic modification. Several of these natural products have shown biological and pharmacological activities and serve as the starting point in the development of modern medicines. Screening of crude plant extracts opens the door to the discovery of novel bioactive compounds, and elucidation of their structures leads towards new synthetic preparations, which can be administered in reproducible, accurate doses for particular therapeutic purposes. However, what is needed are rapid screening techniques, structure-based design, bioactivity-safety evaluation, extraction and isolation, and clinical trials for drug development under innovations, which will share the profit of products derived from natural origin. The government sector, industries, and academic institutions also play an essential role in developing biological drugs for human health enhancement. This book comprises four chapters. The first chapter is related to urolithiasis. In this chapter, the types of urinary stone formation in humans, their mechanism, current antiurolithiatic strategies and their complications are discussed precisely and comprehensively. Chapter two declares urinary stone treatment in early civilisation. The third chapter is about globally used antiurolithiatic plants. This chapter is a treasure trove of information covering the importance of plants in combating urolithiasis, their diverse pharmacology, and a comprehensive list of 888 antiurolithiatic plants from 144 families used in 55 countries. The tabular format provides a clear understanding of their historical background, mechanism of action, therapeutic spectrum, and formulations with doses. Hopefully, this book will not only be helpful for the general public but also attract the scientific world to antiurolithiatic drug discovery. This valuable ethnopharmacological information will provide opportunities for the future research and development of new natural antiurolithiatic compounds. We extend our heartfelt gratitude to all the teachers, colleagues, and institutions whose unwavering support and encouragement made this book possible. We reserve a special thanks for the acquisition Editor of LAP Lambert Academic Publishing, Germany, whose inspiration and support were invaluable.
India is undergoing rapid urbanization, leading to significant transformations in land use, infrastructure, and population densities. Concurrently, climate change is intensifying heat waves across the country, exacerbating the vulnerabilities of urban populations. This study explores the intersection of urban growth and climate change, analysing how expanding cities, with their heat-absorbing materials and altered landscapes, contribute to the urban heat island effect. The research highlights how extreme heat waves, fuelled by global warming, are becoming more frequent and severe in Indian cities, affecting public health, energy consumption, and economic productivity. Furthermore, this study reviews adaptive strategies being implemented, such as green infrastructure, sustainable urban planning, and climate resilient policies, and assesses their effectiveness in mitigating the impacts of heat waves. Through an integrated approach combining climate science and urban studies, the paper emphasizes the urgency of rethinking urbanization to build heat-resilient cities in India. underline the importance of immediate policy interventions, public awareness campaigns, and investments in climate adaptation to safeguard the health and livelihoods of urban dwellers in the face of escalating heat risks.
Currently, vehicle to vehicle communication is an important application and thrust area of research. In this paper the author highlighted the workings, executions, implementations and the application of the Internet of Things (IoT) in transport management and vehicle to vehicle communication systems. The main advantage of this Industry 4.0 based IoT technology is that it helps us to reduce road traffic and accidents. The limitations of GPS like accuracy, precision, effective analysis, etc. has led to the evolution of Mobile based V2V communication which is more effective, error proof, result oriented and smart. For proper analysis of traffic vehicle to vehicle communication is established. Random Data from vehicles taken by numerous sensors. Any car coming in its variety could effortlessly share the data by either of two cars nearby. With the help of vehicle to vehicle communication we can provide a path of emergency vehicles to reach the destination quickly. Based on the V2V application, Red and Green signals can be marked on the path as per traffic density and the emergency vehicle can take the shortest, fastest and low density route. Similar such examples are elaborated in the current research manuscript that will help the researcher in effectively finding the research gap for further advancement, analysis, innovation and optimization.
Simply put, advertising is an important marketing strategy that works in conjunction with information and persuasion channels. Every single person is exposed to commercials on a daily basis. They've become an inseparable part of the print medium, whether it's newspapers or magazines, over time. This is also true in the case of broadcast media, where ad-commercials predominate. The Indian advertising industry has grown tremendously from a small business to a full-fledged industry. The purpose of this study is to determine the advertising attractions and the influence they have on Indian culture. Advertisements in India are not only used to sell products. It sells dreams, visions, and the ideal way of life, while also reinforcing stereotyped values. The longer an individual is exposed to an advertisement, the more likely it is that it will effect them. The appeals' goal is to change how people think about themselves and how they decide whether or not to buy certain things will benefit them. Because India has such a large population and cultural diversity, the advertising industry has created a wide range of advertisements to capture people's attention and persuade them to buy products. The appeals are written in such a way that they have an impact on people's purchasing decisions.
The study of molluscan animals is called Malacology and the study of molluscan shell is called as conchology. The scaling of metabolic rates with body mass is one of the best known and most studied characteristics of aquatic animals. We studied here how body size is related to rate of oxygen consumption, ammonia excretion and O: N ratio in Freshwater Bivalve Mollusc Lamellidens marginalis species in an attempt to know how body size specific changes affect their metabolism. The freshwater bivalve molluscs with specific body size i.e. small (76-79 mm in shell-length) and large (90-94 mm in shell-length) were chosen for experimental work from Bhima River at Siddhatek on April and May during summer. The adult bivalve molluscs with small body size reported high value in rate of oxygen consumption and O: N ratio but rate of ammonia excretion was low value in small body sized bivalves compared to large ones. The results are discussed in the flush of metabolic processes in fresh-water bivalve molluscs.
The dominant sequence transduction models are based on complex recurrent or convolutional neural networks that include an encoder and a decoder. The best performing models also connect the encoder and decoder through an attention mechanism. We propose a new simple network architecture, the Transformer, based solely on attention mechanisms, dispensing with recurrence and convolutions entirely. Experiments on two machine translation tasks show these models to be superior in quality while being more parallelizable and requiring significantly less time to train. Our model achieves 28.4 BLEU on the WMT 2014 Englishto-German translation task, improving over the existing best results, including ensembles, by over 2 BLEU. On the WMT 2014 English-to-French translation task, our model establishes a new single-model state-of-the-art BLEU score of 41.0 after training for 3.5 days on eight GPUs, a small fraction of the training costs of the best models from the literature.
An attempt was made for screening of salt tolerant against sodium chloride (NaCl) salt and growth promotion efficacy of eight different phosphate solubilizing bacterial (PSB) isolates under in vitro conditions. An efficient isolate which exhibited maximum phosphate solubilization, salt tolerant, Indole-3-Acetic Acid (IAA) production and root colonization potential in maximum concentration of NaCl (7%) was identified as Bacillus cereus based on 16S rRNA sequencing. It was recorded that highest phosphate solubilization in 7% NaCl concentration (70% and 374 μg/mL) in agar plate and broth assay respectively. IAA production was observed to be decreased when salt concentration increases, the isolate showed significant amount of IAA in normal culture media without amendment of NaCl (74.94 μg/mL) and at 7% gradual decrease of IAA production was observed (30 μg/mL). Maximum colonization of isolate in the roots of Zea mays was also observed in the study.