Artificial Intelligence (AI) has emerged as a transformative force in the healthcare domain, revolutionizing various aspects of medical research, diagnostics, treatment, and patient care. This paper provides an overview of recent developments and applications of AI in healthcare, highlighting its potential to enhance efficiency, accuracy, and accessibility in medical practices. The integration of machine learning algorithms, natural language processing, and computer vision techniques has enabled AI systems to analyze vast amounts of medical data, support clinical decision-making, and personalize treatment plans. Additionally, AI-powered technologies play a crucial role in predictive analytics, early disease detection, and the optimization of healthcare workflows. Despite the promising advancements, challenges related to data privacy, ethical considerations, and regulatory frameworks need to be addressed to fully harness the benefits of AI in healthcare.
The aim of this study is to identify the move from cultural to creative cultural tourism as new model for meeting tourists' demands for creative experiences. Hence, traditional cultural tourism must reinvent itself as creative tourism for those creative tourists seeking more interactive experiences. This new trend in creative cultural tourism has emerged from the changes in the production of cultural tourist commodities, the skilled tourist activities, and new consumption patterns. Moreover, creative cultural tourism can solve those problems experienced by traditional cultural tourists. A literature review confirmed that a move to creative cultural tourism, or intangible heritage (i.e., linguistic diversity or gastronomy), from tangible cultural attractions (i.e., museums, monuments, and so forth) increases the attractiveness of tourism destinations. In addition, this study explains the transformation from traditional cultural to creative cultural tourism.
Background: Gestational hypertension (GHTN) is defined as a new rise in blood pressure (BP) ≥140/90 mm Hg, presenting at 20 weeks gestation without significant proteinuria. Worldwide, 4.4%-15% of all pregnancies are complicated by HTN. The aim of this study was to determine the incidence of GHTN among pregnant women in Enugu State, Southeast Nigeria with a view to improving and strengthening antenatal services in the State to help reduce the proportion of maternal mortality and fetal outcomes attributable to GHTN and reduce the overall prevalence of HTN in the country. Methods: Records of BP, biodata and laboratory investigations (urinalysis, full blood count) of women who attended antenatal clinics in six selected state hospitals (2006-2015) were examined. Data were analyzed as proportions, t-test, ANOVA and Pearson product moment correlations using Maxstat (version 3.60) statistical software. Results: The overall incidence of GHTN was 5.9% with annual fluctuations with peaks in 2010 and 2014. There were significant differences in incidence among the age groups (<20>35 years) (p<0 p=0.0016).>35 years) and GHTN (r=0.932, p=0.0069). Between parity and GHTN, there was also positive, strong and significant correlation (r=0.813, p=0.0491). Conclusions: With an incidence of GHTN at 5.9%, there is need to improve and sustain adequate antenatal services in order to help reduce the proportion of the country’s maternal mortality attributable to hypertensive disorders of pregnancy.
An Indonesian lady aged 52 years old presented to the emergency department with a 2-week history of lower backache. One-week later, she developed urine retention followed by bilateral lower limb weakness, and since then, she has been unable to walk. Her medical history, family history, and social history were unremarkable. She has no previous history of trauma or similar presented symptoms. Clinical examination showed spastic paraparesis with hyperreflexia. Blood chemistry showed HbA1c of 11.6, and the fasting blood glucose was 14.2 mmol/l. Contrast-enhanced magnetic resonance imaging (MRI) showed an epidural collection extending from T9 to S1 and occupying predominantly the anterior epidural space, with extension toward the posterior epidural space in the lumbosacral region (Fig. 1a). The provisional diagnosis was Pott’s disease, and lumbar (L) hemilaminectomy at L2 was done to drain the epidural collection. Mycobacterium tuberculosis was not detected by acid-fast bacilli or polymerase chain reaction testing of the specimen. However, the drained epdural collection was positive for penicillin-susceptible streptococci Agalactiae. Blood cultures were negative, and transesophageal echocardiography did not show any vegetations. The patient received intravenous ampicillin for 2 weeks, then switched to oral antibiotics for another 6 weeks, and was referred to the rehabilitation center, where she improved and was discharged after 8 weeks with a walker. A repeat MRI (Fig. 1b) showed a complete resolution of the previously described epidural collection.
Family businesses must harness the full potential of their human resources and maintain employee loyalty to achieve the companies’ objectives effectively. This study examines the influence of transformational leadership on employee commitment through work-life balance and workplace social support. The research was conducted from August to December 2023 using an online questionnaire distributed to employees in a family firm in Medan, Indonesia. The data were then analyzed using PLS-SEM. The results show that transformational leadership significantly effects employee commitment, work-life balance, and workplace social support. However, although workplace social support mediates the relationship between transformational leadership and employee commitment, work-life balance fails to do so. It was also found that work-life balance has no direct influence on employee commitment. Using an IPMA analysis, this study highlights the importance of transformational leadership and workplace social support in the family business environment. Transformational leadership has also been shown to have the best performance and effect on employee commitment. Managers should prioritize these aspects to reduce employees’ stress levels, improve psychological well-being, and increase job satisfaction, leading to a more committed, high-performance workforce.
Worldwide, the threat created by antibiotic resistance to public health calls for immediate action. Antibiotic resistance is one of the main causes of the emergence and spread of dispensing of antibiotics without a prescription. This study aims to investigate the dispensing of antibiotics without a prescription and the reason behind that in the community pharmacy in Libya. The study was randomized analytical conducted between March and April 2023 among pharmacists and assistant pharmacists employed by community pharmacies in various Libyan areas Tripoli, Zawia, and Sabratha. The data were analyzed by Fisher's exact and Chi-square tests to predict the determinations of dispensing antibiotics without prescriptions. In this study, a total of 293 participants were included, 63 had been excluded because they did not meet the inclusion of the study. The remaining 230 were enrolled for final analysis, most of them were female subjects (70.7%). Findings showed that 78.7% of the participants consulted with patients about the reason for requesting a specific type of antibiotic, while 68.7% dispensed antibiotics with probiotics. Study participants with 2 - 4 years' work experience were 76.6% higher toward dispensing of antibiotics without a prescription (P=0.683). The major reason for dispensing antibiotics without prescriptions were pharmacists knowledgeable enough to give a patient antibiotics without a prescription (68.3%). In Libya, misuse of antibiotics by the public is widespread. People can purchase antibiotics without prescription. Thus, dispensing of antibiotics without a prescription in community pharmacies is an alarming issue in Libya which can increase antibiotics resistance. Pharmacists' knowledgeable is high in dispensing patients antibiotics without a prescription, but patient pressure and financial issues are the major reasons behind dispensing antibiotics without a prescription. It can be recommended that the importance of antimicrobial stewardship and the need for ongoing education support for community pharmacy professionals is of importance.
Mediterranean journal of pharmacy and pharmaceutical sciences
Impurity is something that is impure or makes something else impure. An impure substance may be defined as follows: a substance of interest mixed or impregnated with an extraneous or usually inferior substance, from the standpoint of its usage, the drug substance is compromised in terms of purity even if it contains another material with superior pharmacological or toxicological properties. The impurity may be developed either during formulation, or upon aging of both API’s and formulated API’s in medicines. The presence of these unwanted chemicals, even in small amount, may influence the efficacy and safety of the pharmaceutical products. The impurities are not necessarily always inferior. Highly sophisticated instrumentation, such as mass spectra meters attached to a Gas Chromatography or HPLC, are inevitable tools in the identification of minor components (drugs, impurities, degradation products, metabolites) in various matrices. Present article reveals different impurities found in the API’s, methods for identifying them and the possible measures to deal with the interferences caused by them in pharmaceutical analysis.
The COVID-19 crisis has impacted all dimensions of our lives say it as the public health, the labour system, the social interaction, the political debate, the use of public spaces, the economy, the environment, and last but not the least it has proved to be a major contributor to the cultural value system of the individual living in society. This research paper is to analyse and understand the changes enforced by this pandemic on Indian culture and individual of the society. It also analyses the context of COVID-19 scenario with special reference to Indian culture and Hofstede’s theory of cultural dimension. This research paper is an attempt to emphasize the changes in culture and value system during the COVID-19 pandemic faced by India. India is enriched enough in cultural dimensions to combat COVID-19. The Hofstede’s model analysed in depth also leads to this finding that it also fits well in the present context. Thus, it is hereby summed up that as India is enriched in its cultural values it has posed itself as a fighter for this pandemic
The contribution of financial perspective measures to improving organizational performance is empirically examined in this article. The study examines how financial metrics like ROI, cost control, profitability, and revenue growth relate to organizational effectiveness using the case of MTN Ghana. It is based on the balanced scorecard framework. The study uses a quantitative approach to investigate the relationship between financial performance metrics and important success indicators like market share, operational effectiveness, and shareholder value, using data from a dataset of different companies in multiple industries. The results of the study show how important financial perspective metrics are for reaching competitive advantage and sustainable growth. Businesses that put a high priority on strategic fiscal management typically perform better, especially when it comes to cost-effectiveness, liquidity, and profit margins. But the study also highlights the drawbacks of depending only on financial indicators. To create a more thorough performance evaluation system, it emphasizes the need to combine financial measurements with non-financial indicators like employee development, internal processes, and customer satisfaction. In summary, the study offers practitioners and scholars useful information by offering evidence-based recommendations for enhancing financial strategies. Organizations can develop a balanced approach to performance measurement that promotes long-term success by using both financial and non-financial metrics. The article ends with practical suggestions for businesses looking to increase output and streamline their budgets.
The diversity of reactogenicity and its variation in terms of risk and prevalence among populations had raised the need to study and evaluate the reactogenicity of different COVID-19 vaccines in our region. Thus, this study aimed to estimate the prevalence of reactogenicity of COVID-19 vaccines and compare the three vaccines (AstraZeneca-Oxford, Sinovac and sputnik V). An analytical cross-sectional study was conducted using a semi-structured telephonic interview with a sample size of 430 individuals who received one of the included COVID-19 vaccines (AstraZeneca, Sinovac or sputnik V) and were recorded at one of the vaccination centers' records that were affiliated with Aljamail Department of the National Centre for Disease Control, Libya. 410 Libyan participants met the inclusion criteria and were enrolled in the final analysis. The study has shown that 57.3% (CI 52.7-62) of the participants had at least one reactogenic event. Pyrexia (40.7%), headache (27.3%) and fatigue (19.5%) were the most common reactogenic events. In conclusion: the study found that reactogenic events were mild to moderate and the COVID-19 vaccines were safe and encouraged our community to be vaccinated. However, prospective studies with larger sample sizes, longer follow-up and inclusion of important laboratory parameters such as IgG and IgM immunoglobulins are recommended to better understand the relationship between the reactogenicities of COVID-19 vaccines with immunity system development and the factors associated with it.
Mediterranean journal of pharmacy and pharmaceutical sciences
Accurate diagnosis of the cause of acute or chronic kidney dysfunction may require a percutaneous kidney biopsy (PKB). Unfortunately, the invasive nature of the procedure can lead to potential complications that may discourage the KBs. Lack of appropriate communication skills, experienced personnel and equipment, and high procedure costs can negatively impact complication rates and the frequency of conducted KBs. This nonsystematic review assesses KB procedures, indications, contraindications, complications, post-KB monitoring time, and cost. We looked for reviews and original articles published between January 2010 and Jan 2025 on Google, Google Scholar, and PubMed. Different keywords, phrases, and sentences include PKB, renal biopsy, native PKB, ultrasound guide, CT-guided, PKB, allograft PKB, and PKB procedures. KB makes histopathological and immunohistological diagnosis possible, which are necessary for diagnosis and treatment. It is often used despite the known complications. KB and other biochemical assays have tracked transplant rejection and antirejection drugs. Automatic gun spiral needles sizes 14 and 16 capture enough samples with fewer complications than gauge sizes 18 and 20. KB cost is another issue, especially in low-income areas, and deserves additional study.
The conservation of traditional medicinal knowledge opens the door towards modern aspects of herbal drug discovery. It started with knowledge exchange through ethnic groups through oral tradition and then in the documented form. Herbaria conserving identified and authenticated plants for future correspondence play an important role. In presenting the review, the authors have declared different auxiliary aspects of herbaria for phytomedicinal research.
India is a diverse land with a population of approximately 1.3 billion,1 placing India at the second position in the world in terms of population. Among these, Seventh-day Adventists' existence, as per the statistics of 2019, is 1.14 million.2 India is a richly diverse community, inclosing a diverse range of ethnic groups, each, not just different, but on occasion quite the opposite.
Araucaria columnaris is one of the ornamental plants of all over the world. It is commonly known as Christmas tree. In the present study tree exudates – resin from the bark of the Araucaria columnaris belonging to the family Araucariaceae were investigated for phytochemical and antibacterial activity. The resin was separately extracted with different solvents based on its polarity, water, methanol, ethyl acetate and benzene. The extracts were screened for phyto-chemical analysis, the result shows that methanolic extract involved in extraction of large number of phytochemicals when compared with other extracts and subjected to antibacterial assay against major human pathogens. Methanolic extract act as good inhibitory agent against major microorganisms. This finding revealed that methanolic resin extract of Araucaria columnaris had significant potential for the control of dreadful diseases causing human pathogens.
A mobile adhoc network is a Self-configuring network of mobile routers connected by wireless links. In the mobile adhoc network, each and every device moves independently in any direction so that there are frequent changes in the links. It is essential to learn the position of the neighbors because there is increase in location-aware services. So, there is a chance that the malicious nodes are easily abused the process. The significant problem in mobile networks is correctness of node locations and also it is primarily challenging in the presence of adversaries. So, the neighbor position verification protocol is used to a fully distributed, a lightweight NPV procedure which allows each node to obtain the locations advertised by its neighbors and asses their truthfulness. Further to extend neighbor position verification protocols in the proactive model that need to each node constantly verify the position of its neighbors. So, we introduce a technique called secure link state updating which provides secure proactive topology discovery that is multiply useful for the network operation. This technique is vigorous against individual attackers, it is capable to adjust its capacity between local and network-wide topology discovery, and also operating in networks of frequently changing topology and membership nodes. Experimental results show that the proposed system is high efficiency in terms of security when compared to the existing system.
formulation and evaluation of herbal face pace pack
The prevalence of vitamin D deficiency has recently been recognized in different parts of the world, even affecting healthy populations. The deficiency of vitamin D can lead to rickets in children and osteomalacia in adults. Few studies have been done to evaluate the status of vitamin D in the medical community around the world. No studies have been done in Libya to evaluate the status of vitamin D in medical students. The aim of this study was to evaluate the prevalence of low level of vitamin D in among healthy Libyan medical students of first year in University of Tripoli, Tripoli. Prospective study was conducted on 100 medical students of first year in Faculty of Medicine with a mean age of 19.5 years, 38 males and 62 females. Blood samples were taken and investigated for different biochemical parameters including serum calcium, serum vitamin D and serum parathyroid hormone levels. Questionnaire containing different data was completed for each student including personal data (age, address, nationality, and other data related to vitamin D deficiency. The prevalence of vitamin D deficiency in all the participated students was 74% (58.7% in males and 83.8% in females), while 21% had vitamin D insufficiency (28% in males and 16.12% in females). Only 5% of the students that had normal vitamin D was males. The mean 25-hydroxy vitamin D level was 19.49 ± 8.56 ng/ml in males and 12.08 ± 6.70 ng/ml in female students. Statistical analysis revealed that there is a highly significant difference among the student in vitamin D deficiency. In conclusion, low concentration of vitamin D is highly prevalent among the medical students included. An urgent action has to be taken in order to prevent adverse consequences of low vitamin D in young population.
Mediterranean journal of pharmacy and pharmaceutical sciences
Health tourism is a visit made to different regions in order to improve the physical well-being of the person. Medical tourism, on the other hand, is the sub-branch of health tourism and it is a form of travel that is used for medical treatment and also the tourism activities of the country visited. Under the name of medical tourism in women's health; cosmetic surgery, reproduction, birth, IVF, gynecological treatments, abortion, abortion and newborn care travels are included. It has been observed that many women travel around the world and in Turkey for these reasons and medical tourism has an important place in terms of women's health. The purpose of this review is to examine the impact of medical tourism on women's health in line with the literature
Four Trichoderma species with known biocontrol activity (T. harzianum, T. hamantum, T. viride and T. virens) were tested for their efficacy against Cephalosporium acremonium, a causal organism of Black bundle disease in maize. Interactions between the fungi were assessed in vitro to study mutual antagonisms. Among the four bio-agents, T. hamantum proved to be promising which showed maximum inhibition (51.3%) followed by T. virens (45.2%), T. harzianum (44.6%) and T. viride (20.3%). T. hamantum was also found to be hyperparasite on C. acremonium whereas, T. harzianum and T. viride showed mycelial deformation. The volatile toxicants released by all the Trichoderma spp. were inferior in inhibiting the growth of C. acremonium when compared to the control as evident by inverted plate technique. The results of in vivo experiments confirmed the results from the in vitro study and showed that all the four bio-agents significantly reduced the disease incidence of Black bundle disease.
Arisaema jacquemontii Blume (Araceae) is a medicinally important plant for treating different diseases, especially dermatological disorders. Alkaloids, phenols, terpenes, flavonoids, glycosides, and tannins have been reported from this plant. Antioxidant, antifungal, antibacterial and anticancer activities are also shown by Arisaema jacquemontii. The present review attempts to compile all the previous data based on its medicinal uses, phytochemistry and pharmacology reported in the earlier articles.