Cystic fibrosis is a challenging disease which creates many complications. The impact caused from cystic fibrosis on an adolescent is a challenging phase for their lives. Negative impacts like the society’s pressure, anxiety and depression are few common reasons that are being unspoken and ignored due to complexity of the disease. This study is aimed to identify the necessary gaps and educate the necessary policy makers and CF center health care team to have a better understanding about the context of the aftermath of cystic fibrosis and enhance better patient care. More over this systematic review also points out the main trends in this field of study. Qualitative study and quantitative are prominently used research methods to gain an understanding the about the gaps in the research. However, there is still a scarcity of quantitative and mixed research methods. Furthermore, limitations such as language, cultural influences were identified whilst going through the analysis. Overall through the information given in the following in this study more information regarding that warrants answers can be identified which will lead to proper care towards the teenagers who suffers from cystic fibrosis

Chanitha pemasena

With the projected growth of the global electric vehicle market that is estimated to double in the next decade, the expansion of the battery manufacturing capacity will primarily depend on the auto market’s electrification. Moreover, the market growth puts new requirements on the end-of-life phase and the recycling components. Therefore, the report provides a feasibility research study aimed at investigating the international initiative. It identifies the production and exportation of Lithium-Ion Batteries to the Chinese electric vehicle manufacturers and consumers as a business opportunity and discusses the gaps in the current market. The research also includes a look at the cost estimates that are bound to affect the company. Additionally, the report also includes recommendations for the company to ensure that it understands the policy frameworks and market systems for electric cars adoption. By doing so, the report discusses several aspects of the entire Lithium-Ion Battery business, justifying the business idea.

Mohamed sorogy

This Document addresses the main trends around healthy eating in the global, Latin American, and Peruvian environment related to the proposed business plan. Analysis shows that with an increase in the population around the world it is important for food producing organizations to introduce new food products in order to be in the race of famous food brands. Based on qualitative and quantitative data from various sources, it is possible to know the opportunities for a plant-based burger business. This assignment aims to recognize if there is a favorable evolution for the proposal of this business plan at the different levels of the environment. The brand focused on this assignment in KFC. A plan for introducing green burgers in Peru and other regions of Latin America was developed in this paper.

Zamzam abdelazim

Potato starch extraction is a critical process with implications across various industries, including food, pharmaceuticals, and bioplastics. This review explores current techniques, challenges, and future opportunities in potato starch extraction. Traditional methods such as compression or wet grinding, enzymatic processes, and microwave-assisted extraction are examined for their efficiency, advantages, and limitations. The paper emphasizes the importance of quality control measures to ensure the purity and safety of the extracted starch. Critical quality control aspects include raw material inspection, monitoring during processing, purity and composition analysis, and adherence to national and international standards. Innovations in extraction methods, including enzymatic and green solvent extraction, ultrasonic and microwave-assisted techniques, and advancements in nanotechnology and biotechnological approaches, are highlighted as trends driving the industry towards greater sustainability and efficiency. The clean label movement also reflects a consumer-driven shift towards natural, minimally processed ingredients, influencing industry practices and regulatory compliance. The future of potato starch extraction holds significant promise, with the integration of sustainable practices and technological innovations to meet evolving market demands and regulatory standards, underscoring the need for continuous research and development in the field.

Dr. salman ahmed

Long periods of free-movement Restrictions may negatively affect Cardio-Pulmonary fitness and health. As, the COVID-19 virus primarily affects Respiratory system, and also associated with cardiovascular disease, can induce the following complications like thrombosis, myocardities, Interstitial pulmonary fibrosis, diffuse alveolar damage and persistent decline in lung function, as the lung capacity decreases it may results in decrease in Cardio Pulmonary endurance. The Present study investigated changes after the COVID-19 confinement in total distance covered in 6 minutes by patients and correlation between 6 minutes walk test vs. oxygen saturation; Results suggest that the Mean ± SD of age is 43.4 ± 10.8years. Male: Female 1:0.5.Mean ± SD of total distance walked in 6 minutes by patients is 443.5 ± 55 compared with Hypothetical mean (normative value) is 571 ± 90.Correlation between Total distance walked in 6 minutes vs. oxygen saturation is r = 0.055.

Nagarjuna narayanasetti

The seeds of Phaseolus vulgaris are known as common beans or kidney beans. The dry seeds are eaten as pulse and are enriched with protein, fiber, starch, B vitamins (B1, B6, B9), iron, potassium and selenium. Beans also contain about 1-2 % of fixed oil. Phaseolus vulgaris is linked to anticancer, antihyperlipidemic, hypoglycemic, and antioxidant actions. The fixed oil of Phaseolus vulgaris (PVFO) seeds is extracted with hexane and used in this study to assess acute oral toxicity, analgesic (by acetic acid-induced writhing, hot plate and tail flick tests in mice) and antiinflammatory (by carrageenan-induced paw edema in rats) actions. Four groups were made (n=6): Group-I: Normal Saline Control (2ml/kg), Group-II: PVFO (2ml/kg), Group-III: PVFO (4ml/kg) and Group-IV: Standard Acetylsalicylic acid (ASA 300 mg/kg). PVFO in 2ml/kg and 4ml/kg doses demonstrated analgesic and anti-inflammatory activities, but in hot plate, results were unreliable as significant activity started after 90 minutes. A 5ml/kg dose was administered orally in mice for a toxicity test, and no toxicity symptoms were observed. Therefore, PVFO is safe for oral use up to 5ml/kg and may possess analgesic and anti-inflammatory actions.

Dr. salman ahmed

The objective of the paper is to predict corporate bankruptcy of selected telecom service sector companies. The study ranges for a period of ten years from 2006-2007 to 2015-2016 for three selected telecom service sector. By applying Altman's Z-score model the study analyze the financial position of the companies and suggests the financial components to be concentrated to improve the financial health. Further the study suggests that the companies should regularly estimate Z-score for making strategies to improve their financial position.

Dr. jeyalakshmi p

Plants produce a diverse range of bioactive compounds making them a rich source of different types of medicines. Ornamental plants are cultivated for adornment and to enhance the appearance of houses and also for commercial purposes. However, only very few of these ornamental plant species have found to be used in medicine and only little literature exit on their chemical and biological actions. In the present study, the evaluation of antimicrobial activities and identification of bioactive compounds using TLC and GC-MS of the A. columnaris bark extract were performed. In GC-MS bioactive compounds with medicinal value were identified, such as Benzoic acid, 1H-N-Hydroxynaphth (2,3) imidazole-6,7-dicarboximide, 2-Propenoic acid, 3-(4-methoxyphenyl), 1H-N-Hydroxynaphth (2,3-d) imidazole-6,7-dicarboximi. To prove the nontoxic nature of the plant, its crude bark extract was subjected to toxicity study using human embryonic kidney cell line. It reveal that the plant is minimal toxic to the human kidney cell line so usage of appropriate level will found to be safe and also carrying out some structural modification will help in the extraction of new drugs for pharmaceutical purpose.

Dr. saranya devi k

Purchasing is one of the key managerial activities in every organisation, its significance having been identified during the 19th century. According to Kasilingham (2012, p.57), the period shortly before the Second World War marked the discovery of the fact that a firm’s success was not so much dependent upon what it was capable of selling but rather on how able organisations were to acquire necessary services together with materials from vendors. This discovery was triggered by a global shortage of virtually all fundamental materials for supporting operations, coupled with an abnormal rise in prices following the First World War. Since that time, purchasing has gained significance for the critical role it plays towards ensuring continuity of production (Hacioglu, 2019 p.265). Worth noting is that purchasing acts as “an interface between suppliers and functional areas within the buying organisation” (Crandall, Crandall & Chen, 2009 p.265). Among some of the functional areas that are influenced by purchasing are finance, marketing, production, and quality assurance (Magad & Amos, 2013 p.225). A vital deduction that can be made from this latter statement is that for the purchasing function to proceed smoothly and make the other functions- and the entire organisation- active, organisations must cultivate and maintain good relationships with suppliers and all other players in the supply chain. In addition, organisations operate in environments that are highly unpredictable; the techniques needed to perform the purchasing function become more refined almost every day due to constant changes in the market (Kasilingam, 2012 p.57). Subsequently, there is a need for managers in organisations to understand and embrace the idea of sustainable procurement.

Mohamed sorogy

In this research study, the mechanical properties of several Polymer matrix composites are investigated. These composites are multi-phase materials in which reinforcing materials are properly mixed with a polymer matrix. More precisely, Nylon 6 reinforced with 5, 15 and 25 wt. % of silicon carbide (SiC) and Nylon 6 reinforced with 5, 15 and 25 wt. % of boron carbide (B4C), prepared by means of an injection moulding process at three different injection pressures are considered. Specific attention is paid to the tensile and impact strength of these composites. The Taguchi technique is used to optimize the process parameters such as reinforcement material, its percentage and the injection pressure. It is observed that the specimens 5% SiC with 80 MPa injection pressure display a better tensile strength and similarly the specimen 5% B4C with 90 MPa injection pressure have a superior impact strength.

Boopathy govindarajan

Object: In the competitive world of the market economy, every economic unit tries organizing everyday activities. Creating a set of suitable and cost-efficient organizational structures and making competitive products and services, top managers should find the mechanisms of building alternative ways of organizational structures. Methods: This paper presents the traditional and modern management structures, their historical steps, and developed methods. In this footfall of the market economy, companies in developing countries should build their management system’s organizational structure. They should advance a management system, managerial behaviours, and new management styles of developed ones. For this purpose in this research has learned organizational structures of developed companies. The investigation discusses the emergence, formation, and modern appearance of management structures that evaluate organizational structures’ importance in enterprises and companies’ activities, using vivid examples. Findings: Then, it has shown some forms of developed organizational structures of companies with the assessment of their highest role in management. In the conclusions and recommendations, we offer our approaches to solving existing organizational problems using the historical period of development to this day.

Ikboljon odashev mashrabjonovich

Breast cancer is the most prevalent invasive form of cancer in females and poses a significant challenge to overcoming the disease burden. The growth in global cancer deaths mandates the discovery of new efficacious natural anti-tumor treatments. In this regard, aquatic species offer a rich supply of possible drugs. Studies have shown that several marine peptides damage cancer cells by a broad range of pathways, including apoptosis, microtubule balance disturbances, and suppression of angiogenesis. Many side effects, including immune response suppression, characterise traditional chemotherapeutic agents. The discovery of novel putative anti-cancer peptides with lesser toxicity is therefore necessary and timely, especially those able to thwart multi-drug resistance (MDR). This review addresses marine anti-cancer peptides for the treatment of breast cancer.

Dr. salman ahmed

It is virtually impossible to mention the phrase ‘project management’ without introducing the concept of risk management. As Hillson (2016, p.11) states, “risks [are] particularly relevant to projects” suggesting that effective management of risk is an integral ingredient for project success. The close link that exists between projects and risks may be deduced by the definition of the word ‘project’. In simple terms, projects refer to unique endeavours undertaken with the aim of achieving desired outcomes. These endeavours typically specific start and completion dates, and involve resource, time and cost constraints. These characteristics imply that projects are intended to deliver identifiable benefits to the organisation; these benefits, however, are not enjoyed immediately even if the project is completed. On the contrary, projects commonly create capabilities that call for operation or utilisation for the actual gains to be generated (Hillson, 2016 p.11). The interpretation of this is that projects have a risk element in that they contain a potential reward and possibility of loss. For this reason, project managers must be well-versed with risk management.

Mohamed sorogy

Background: Hypertension (HTN) is defined as a blood pressure (BP) ≥140/90 mm Hg. The prevalence and mortality from HTN, globally and locally, have been on the increase since the 1980s. This study aimed to detect young adults (18-40 years) in Enugu State who are hypertensive, in order to raise the awareness that HTN is also common in young adults. Its early diagnosis and management could help to reverse the trend in the number of cases of HTN in Nigeria which had been predicted could hit 39.1 million by 2030 if the present trend is allowed to continue. Methods: Participants were administered with structured questionnaire. Their BPs, heights and weights were measured using sphygmomanometer, stadiometer and scale balance respectively. Data were analyzed as proportions, Pearson product moment correlations and Chi square tests using MaxStat (version 3.60) statistical software. Results: The overall prevalence of HTN was 21.3%; 20.7% in the 18-29 years age group; 25.9% in the 30-40 years age group; 24.3%, in males; and 20.3% in females. Pearson product moment correlation coefficient r between age and HTN=0.462, between sex and HTN=0.328, between family history and HTN = 0.513, between salt intake and HTN=0.613, between BMI and HTN=0.152, between physical activity and HTN=0.293, between smoking and HTN=0.308. Conclusions: HTN in young adults is more common than previously thought and if unmanaged in early life usually progresses to HTN later in life.

Emmanuel umegbolu

This study was carried out to evaluate the effects of thermal processing techniques on the nutrient and antinutrient contents of pigeon pea (Cajanus cajan) flours. The pigeon pea seeds were sorted, cleaned and divided into five equal lots of 0.5kg each. Four lots of pigeon pea seeds were processed into blanched, boiled, roasted, and autoclaved pigeon pea flours, while the fifth lot was processed raw and used as control. The raw and thermally processed samples obtained were analysed for nutrient and antinutrient composition using standard methods. The proximate composition of the samples showed that the flours had a range of 8.61 - 11.46 % moisture, 21.13 - 23.94 % crude protein, 1.26 - 1.68 % fat, 5.12 – 6.10 % crude fibre, 1.74 – 2.97 % ash, 55.56 – 60.41 % carbohydrate and 333.45 - 342.75 kJ/100g energy, respectively. The mineral composition showed that the flours contained 86.24 – 144.72 mg/100g calcium, 137.80 – 170.33 mg/100g magnesium, 125.86 - 156.76 mg/100g potassium, 66.66 – 95.62 mg/100g sodium, 4.38 – 6.64 mg/100g iron and 130.27 – 178.29 mg/100g phosphorus, respectively. The vitamin content of the flours were 3.09 - 4.33 mg/100g ascorbic acid, 0.05 - 0.17 mg/100g thiamine, 0.03 - 0.21 mg/100g riboflavin, 0.13 - 0.28 mg/100g niacin, 3.21 - 6.25 mg/100g vitamin A and 1.10 - 2.70 mg/100g vitamin E, respectively. The antinutrient composition of the flours also showed that the levels of trypsin inhibitor, tannin, phytate, oxalate, saponin and haemagglutinin ranged from, 2.30 – 5.61 Tiu/mg, 0.81 – 1.5mg/100g, 1.12 - 4.18mg/100g, 0.48-4.01 mg/100g, 1.28 – 3.66 mg/100g and 1.30 – 7.44 Hiu/g, respectively. Therefore, the study showed that thermally processed pigeon pea flours could be used as nutrient dense ingredients in the preparation of a wide range of foods for children, adolescents and aged adults especially in developing countries where the problems of protein-energy malnutrition and micronutrients deficiencies are prevalent than the raw sample.

Okechukwu obed chukwuemeka

Obesity is a complex and challenging global public health concern. It is a major disease involving excessive fat accumulation that may impair health. Obesity is dangerous and has been related to a range of long-term health issues that can impact adults and children. According to the World Health Organization, more than one billion people worldwide are obese as of March 2022. In the Libyan situation, the prevalence of obesity has increased among the public over the last decade. This cross-sectional survey-based study is conducted by using self-structured designed questionnaire to evaluate the use of anti-obesity drugs and herbal products among Libyan people. Additionally, considered as an indirect method, pharmacist performance in obesity management was also evaluated. The investigators collected interview data from three different cities in the Northwest of Libya over a period of five months, 2019. A total of 170 participants who use weight loss products were randomly selected to participate in the study after obtaining their verbal consent. The participants' experience with weight reduction agents revealed that more than half of the participants (52.3%) used herbal products while 32.0% of the participants have used drugs of chemical origin and 15.6% have used both (herbal and drugs). The majority of the participants (91.4%) used these products without medical consultation which in turn led to failure to lose and maintain weight with 74.2% gaining weight after stopping using these products. In conclusion, poor pharmacist intervention in obesity management was revealed where the majority of the participants reported that Libyan community pharmacists had not been offering weight management services, monitoring weight loss progress, or explaining the risks of being overweight or obese.

Mediterranean journal of pharmacy and pharmaceutical sciences

It is with more sorrow and tremendous sadness we remember the death of our colleague the Libyan pharmacist, professor Mokhtar Ramadan Haman, at his home in Tripoli, Libya after long-suffering from brain cancer. He died on 02, February 2017 and his immaculate corpse was buried on the following day at the Souk-Al-Ahad cemetery, Bin Ghashir Palace. Professor Haman, was born in Tripoli, Libya, on January 1, 1957. He obtained his Bachelor of Pharmaceutical Sciences in 1981 at the University of Tripoli and his Ph.D. in Pharmacognosy in 1989 at Cardiff University, UK.

Mediterranean journal of pharmacy and pharmaceutical sciences

Anemia, iron deficiency and iron deficiency anemia are common blood disorders. The role of vitamin D was agreed to be regulating in calcium and phosphate absorption and bone metabolism and its deficiency is observed as a crucial nutritional problem. Vitamin D is created under the skin by ultraviolet light. It is usually get vitamins from the food; however, in the case of vitamin D, there simply are not enough rich food sources for people to get adequate amounts in their diet. Its effects on the prevention of diseases such as cardiovascular disease and anemia has received much attention recently. To get sufficient vitamin D, need to be exposed to sunshine or use supplements. Vitamin D3 was found in the largest population as a deficiency. With regard to hemoglobin was the subject whom has less normal range of hemoglobin (19.05%) than international normal range, and in ferritin the low population number was the subject whom has less normal range of ferritin than WHO normal range. The population who has low ferritin also has low vitamin D3 and variable hemoglobin. According international guidelines, optimizing nutrition with daily or intermittent (1 to 3 times per week) iron supplementation, should be considered a first-line intervention in high-risk or high-prevalence groups. Although it is probably less effective than daily iron supplementation, intermittent iron appears to be a useful and cost effective way of controlling anemia and iron deficiency anemia. This may indicate that a positive relation between the low concentration parameter of vitamin D3 and ferritin level but no significant correlation with hemoglobin.

Mediterranean journal of pharmacy and pharmaceutical sciences

This study was conducted to optimize the integration of solar-photovoltaic-distributed energy resources (SPVDERs) within the Nigerian power system networks using an AI-based Particle Swarm Optimization (PSO) Algorithm. By employing a mixed research method, primary and secondary data were gathered to calculate flow analysis, NR method's equations, PSO's position update model, particle swarm optimizer algorithm, and application modeling including Solar-PV DER modeling. The AI-based PSO algorithm design was developed for optimizing SPV-DER integration in Nigerian power system networks, and key parameters and variables that needed consideration were identified. The study also established how the performance of the AI-based PSO algorithm could be evaluated and compared with other optimization techniques for SPV-DER integration within Nigerian power system networks. The study's results showed that voltage limits were within acceptable ranges, and solar power contributions were estimated at 880.10MW with 46,718 panels needed. The study concluded and recommended that investing in AI-powered tools for efficient power distribution; monitoring and resource optimization for sustainable energy sources would optimize performance and unleash Nigeria's sustainable energy potential.

Fxintegrity publishing

eveloping automated systems with a reasonable cost for long-term care for elders is a promising research direction. Such smart systems are based on realizing activities of daily living (ADLs) to enable aging in place while preserving the quality of life of all inhabitants in smart homes. One of the research directions is based on localizing items used by elders to monitor their activities with fine-grained details of the progress. In this paper, we shed the light on this issue by presenting an approach for localizing items in smart homes. The presented method is based on applying machine learning algorithms to Radio Frequency IDentification (RFID) tags readings. Our approach achieves the required task through two stages. The first stage detects in which room the selected object is located. Then, the second one determines the exact position of the selected object inside the detected room. Additionally, we present an efficient approach based on gradient boosted decision trees for detecting the location of the selected object in a real-world smart home. Moreover, we employ some techniques of over- and under- sampling with data clustering for improving the performance of the presented techniques. Many experiments are conducted in this work to evaluate the performance of the presented approach for localizing objects in a real smart home. The results of the experiments have shown that our approach provides remarkable performance.

Shadi abudalfa