Four Trichoderma species with known biocontrol activity (T. harzianum, T. hamantum, T. viride and T. virens) were tested for their efficacy against Cephalosporium acremonium, a causal organism of Black bundle disease in maize. Interactions between the fungi were assessed in vitro to study mutual antagonisms. Among the four bio-agents, T. hamantum proved to be promising which showed maximum inhibition (51.3%) followed by T. virens (45.2%), T. harzianum (44.6%) and T. viride (20.3%). T. hamantum was also found to be hyperparasite on C. acremonium whereas, T. harzianum and T. viride showed mycelial deformation. The volatile toxicants released by all the Trichoderma spp. were inferior in inhibiting the growth of C. acremonium when compared to the control as evident by inverted plate technique. The results of in vivo experiments confirmed the results from the in vitro study and showed that all the four bio-agents significantly reduced the disease incidence of Black bundle disease.
Abstract- The role of support vector machine in the evaluation of English teaching effect is very important, but there is a problem of inaccurate evaluation of results. The traditional English teaching mode cannot solve the accuracy and efficiency of the effect evaluation of students' English teaching and cannot meet the requirements of English teaching effect evaluation. Therefore, this paper proposes a neural network algorithm to innovate and optimize the analysis of support vector machines. Firstly, the relevant theories are used to construct a multi-index English teaching effect evaluation system with teachers and students as the main body, and the indicators are divided according to the data requirements of English teaching effect evaluation indicators to reduce the support vector machine in the interfering factor. Then, the neural network algorithm is used to solve the optimal solution of kernel function parameters and regularization parameters of the support vector machine, and the support vector machine scheme is formed, and the support vector machine results are carried out Comprehensive analysis. MATLAB simulation shows that the evaluation accuracy of the English teaching effect of the neural network algorithm and the support vector machine under certain evaluation criteria Optimal, short evaluation time.
Field experiments were conducted at CCS Haryana Agricultural University, Hisar during kharif season of 2013 and 2014 to determine the effect of weather parameters on the incidence of pod borer complex on early maturing pigeonpea varieties. The study revealed that the infestation of Helicoverpa armigera and Maruca vitrata started with the onset of bud initiation and reached its peak at flowering stage. The maximum H. armigera larval population (1.83 larvae plant-1) was recorded in 1st week of July sown crop, whereas, the maximum incidence of M. vitrata (21.17 webs plant-1) was recorded in 2nd week of July sown crop. The larval population of H. armigera was significantly and positively correlated with the maximum temperature, followed by minimum temperature.Incidence of M. vitrata was negatively correlated with evening relative humidity and wind speed which was significant at p 0.05 level of significance.
In order to perform its basic function of safeguarding life and property, every power system needs an earthing profile that is effective and efficient. Recent studies carried out in the Niger Delta show that its soil is corrosive and frequently attacks the earthing system thereby rendering same ineffective thus posing a great danger to human life and property. This paper reviewed several scholarly literature related to the study for causes of earthing system failures and found that corrosive soils, poor workmanship, wrog choice of earthing materials, lack of maintenance etc. were dominant factors hindering effective and sustainable earthing system in the Niger Delta. The paper, therefore, recommends the regular use of experienced workmen, choice of quality earthing materials, periodic testing, inspection and maintenance as strategies to improve the earthing condition in the area.
Background:- Tribals are weaker section which holds in outstanding number of tribal population in our country. They are not having proper knowledge on osteoporosis. Osteoporosis is a significant problem in aging population especially in females, it impacts structural and social burden on health care services in tribals. Objective:- Aim of this study is to determine the knowledge regarding osteoporosis among tribal premenopausal women in tribal area of Guntur Dist. Andhra Pradesh Methods:- This study is descriptive quantitative study conducted among 177 Sugali women & 23 Chenchu women of tribal area in Guntur Dist. Andhra Pradesh from 2015 November to December 2015. A self-administered questionnaire was used to assess the knowledge on osteoporosis by conducting Pre-Tests on this group of people. After Educational Intervention was given with the help of self-instructional module and also conducted a Post Test on these same Group of people Results:- The mean age was 40 to 50 years. Majority of the participants are 177 (100%) Sugali women and 23 Chenchu women in these 177 in which n.150 (84%) women are having poor knowledge and remaining 27 (16%) women have average knowledge. In Chenchu women 20 (86%) women were having poor knowledge and remaining 3 (14%) women have average knowledge on all five aspects of questions regarding Osteoporosis, Menopause, Diet, Exercises and Preventive Methods. After Educational Intervention was given their knowledge was improved by a fraction on Osteoporosis. In the Post-Test 101 (57%) women gained average knowledge but remaining 76 (43%) women remained with poor knowledge among Sugali Women. Out of 23 (100%) women of Chenchu tribe 7 (30%) women got average knowledge and the remaining 16 (70%) women remained with poor Knowledge on Osteoporosis Conclusion:- Although majority of participants had low level of knowledge on Osteoporosis in all aspects regarding Menopause, Diet, Exercises and Preventive methods of Osteoporosis. They perceived a little knowledge on Osteoporosis in all aspects towards preventing Osteoporosis. Comparitively Sugali women are having better knowledge than Chenchu women in all aspects of Osteoporosis. Key words:- Osteoporosis, Knowledge, Effect, Pre-Menopausal, Tribal Women.
Dietary intake of contaminated food with heavy metals may cause severe risk for the human health. Heavy metals affect adversely a human health. The current study assessed the concentrations of heavy metals including Cu, Zn, Pb and Ni in eggplant (Solanum melongena L.) of urban and rural areas in Bangladesh. The experimental samples of fresh eggplant fruits were collected from six local markets in Jashore, Bangladesh, and the tissues were extracted with nitric acid and hydrogen peroxide. Trace elements in eggplant fruits were estimated with atomic absorption spectrophotometer. Obtained result show that Heavy metal concentrations were high in the urban areas compared to rural areas. Heavy metals in the eggplant fruits of rural and urban areas were: Pb (2.74-18.64), Cu (10.20-67.16), Ni (46.63-148.46), and Zn (86.65-148.73) mg.kg-1 respectively. The concentrations of Pb, Ni and Zn in eggplant were at an excess of safe limits according to the Food and Agriculture and World Health Organizations. While, Cu was lower than the maximum safe limit. The present study concluded that growing eggplants in Jashore areas are heavily contaminated with Pb, Ni and Zn that would be hazardous for consumer’s health. The result of this study will be beneficial for the agricultural policy makers in Bangladesh to take appropriate action and reduce the heavy metal toxicity among fresh food products.
Hepatitis B virus infection is a major health problem worldwide. More than 400 million people are suffering from this infectious disease. Alhagi Maurorum (camel thorn, CTE) is used in Libyan folk medicine for hepatitis. The aim of this study is to investigate the effect of the camel thorn on the hepatitis B virus. After a pharmacological and toxicological screening of camel thorns on experimental animals in our laboratories, in an open-label study, 15 patients of either gender were chosen at random with their consent (consent form signed). The patients had no liver cirrhosis and were not alcoholics. Following clinical testing, the patients were given a low, safe dose of camel thorn powder (2.6 g soaked in boiling water for 10 minutes) three times per day for six months. The viral load was measured before treatment and three and six months after the beginning of the experiment by polymerase chain reaction. The complete blood picture, the level of transaminases, bilirubin, creatinine, blood glucose, lipid profile, thyroid function, and prothrombin were assessed before and after three months after the beginning of the experiment. Our data showed no significant changes in the complete blood picture, creatinine, blood urea, glucose level, bilirubin, alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, lipid profile, prothrombin, and thyroid function. The levels of viral load before, three months after, and six months after the beginning of our study were 1689 ± 289, 558 ± 160, and 271 ± 026 IU per mL, respectively. From this study, we may conclude that the camel thorn is safe and showed activity against viral hepatitis B, however, further investigations are needed by increasing the number of patients and using higher doses of plant extract to explore its mechanism of action. Finally, the mechanism of camel thorn may be related either to its antiviral effect or to the stimulation of either endogenous interferon or the immune system.
Mediterranean journal of pharmacy and pharmaceutical sciences
Crude methanol extracts of the leaves of Adenanthera pavonina L., Peltoforum roxburghii L, Prosopis cineraria L., and Prosopis juliflora DC., were evaluated for anti-emetic activity. Emesis was induced by the oral administration of copper sulphate 50mg/kg body weight to male chicks of four days age. The anti-emetic activity was determined by calculating the mean decrease in number of retching in contrast with those of control. All extracts (150 mg / kg body weight orally) showed anti-emetic activity when compared with standard drug Chlorpromazine at the same dose. Among all the extracts, Prosopis juliflora showed the highest (73.64%) and Adenanthera pavonina showed the lowest (50.17%) anti-emetic activity
Impurity is something that is impure or makes something else impure. An impure substance may be defined as follows: a substance of interest mixed or impregnated with an extraneous or usually inferior substance, from the standpoint of its usage, the drug substance is compromised in terms of purity even if it contains another material with superior pharmacological or toxicological properties. The impurity may be developed either during formulation, or upon aging of both API’s and formulated API’s in medicines. The presence of these unwanted chemicals, even in small amount, may influence the efficacy and safety of the pharmaceutical products. The impurities are not necessarily always inferior. Highly sophisticated instrumentation, such as mass spectra meters attached to a Gas Chromatography or HPLC, are inevitable tools in the identification of minor components (drugs, impurities, degradation products, metabolites) in various matrices. Present article reveals different impurities found in the API’s, methods for identifying them and the possible measures to deal with the interferences caused by them in pharmaceutical analysis.
The problem of chemical fertilizers and pesticides can be solved by the action of plant growth promoting fungi (PGPF). The indigenous fungal isolates obtained from the rhizosphere soil can be used as they are said to solubilize the insoluble zinc, phosphorous, potassium etc. They are known to control the different fungal pathogens and thus promoting the plant growth and health. In the present study, attempt was made to isolate soil beneficial fungi from the rhizosphere soil samples of important medicinal plants such as Aegle marmelos, Azardirachta indica and Citrus limon. A total of 22 fungal isolates was isolated and screened for their efficacy on phosphate and zinc solubilization and antagonistic potential against selected plant pathogenic fungi under in vitro condition and the isolates were identified up to species level.
Background and Objective: The COVID-19 pandemic affected medical care systems including stroke care, globally. In this study, we investigated the impact of the COVID-19 outbreak on stroke care in Hadramout, in terms of rate of admission, access to care, risk factors, clinical presentation, and outcome. Materials and Methods: A hospital-based cross-sectional study comparing all stroke patients admitted to Ibn-seena University Hospital (ISTH), Mukalla, Hadramout, during two periods, May 1–October 31, 2020, during the pandemic of COVID-19 (COVID-19 group), and from May 1 to October 31, 2019 (pre-COVID-19 group). Data collected from patients’ medical record files into a master sheet, and were processed by the Statistical Package for Social Sciences software. Results: There were 117 stroke patients admitted in COVID-19 pandemic in 2020, and 213 patients admitted in the same period in 2019. Stroke admission declined by 45.1% (Odds Ratio [OR]=0.30, 95% confidence interval [CI] [95% CI]: 0.22–0.42, p<0.0001) with no age and sex differences. Hypertension (HTN) and diabetes mellitus were more frequent in COVID-19 group than the pre-COVID-19 group (OR=1.74, 95% CI: 1.08–2.80, p=0.02) and (OR=1.81, 95% CI: 1.14–2, 88, p=0.01), respectively. No significant difference in other risk factors was found. Patients in COVID-19 group arrived the hospital more late than the patients in pre-COVID-19 group (OR=2.63, 95% CI: 1.64–4.21, p<0.0001). Dysphasia and altered consciousness including coma were more common in COVID-19 group compared with pre-COVID-19 group (OR=4.5, 95% CI: 2.18–9.08, p<0.0001) and (OR=3.2, 95% CI: 2.00–5.12, p<0.0001), respectively. Hospital stay was greatly reduced among COVID-19 group as compared with pre-COVID-19 group (02.9±0.31 days vs. 8.6±0.92 days, p<0.0001) Mortality rate was higher among COVID-19 group than the pre-COVID-19 group (41.9% vs. 27.2%, p=007). Conclusion: The number of stroke patients admitted during the COVID-19 pandemic decreased, they arrived late and spent shorter hospital stays while having higher rates of HTN, diabetes, and impaired consciousness with a high mortality rate.
Justicia carnea, a plant rich in bioactive compounds, has traditionally been used as a haemoglobin booster by herbal practitioners in rural areas of Edo State of Nigeria. In this study, the methanol leaves extract of Justicia carnea was investigated for its antisickling potential in hemoglobin SS (HbSS) in-vitro by sodium metabisulphite assay and characterized by Gas Chromatography-Mass Spectrometry (GC-MS) and High-Performance Liquid Chromatography (HPLC). Terpenoids, saponins, glycosides, phenolics, flavonoids and alkaloids were present except tannins. Photomicrograph examinations revealed a reduction of sickle cells with a percentage decrease from 37.50%, and 22.22% down to 3.85% with 100 mg/mL crude extract of Justicia carnea at three durations, respectively. Detected compounds from Gas Chromatography-Mass Spectrometry included hexadecanoic acid methyl ester (Retention time (Rt): 21.46, 05.99%) and 9,12-octadecadienoic acid, methyl ester (Rt: 23.567, 02.59%) while the major constituent was phytol (Rt: 23.741, 67.28%). While kaempferol (Rt: 17.23, 16.72%) was the major component from High-Performance Liquid Chromatography quantification among resveratrol (Rt: 3.7, 13.85%), gallic acid (Rt: 5.88, 3.55%), Justicinol (Rt: 11.85, 01.34%) and phytic acid (Rt 5.06, 01.43 %). These compounds have been cited as physiological agents that reduce inflammation, and oxidative stress and potentially prolong the lifespan of cells across species. The antisickling results from this study corroborate and support the traditional use of the plant in treating patients with sickle cell anemia.
Mediterranean journal of pharmacy and pharmaceutical sciences
Plants are an ancient source of medicine due to the presence of bioactive molecules of various compounds in their different parts. Convolvulus dorycnium plant belongs to the family of wind plants (convolvulaceae). The greatest variety of Convolvulus plants are broadly distributed over the world and was found in Western and Central Asia, Mediterranean, Macaronesia, East Africa, and Arabia. The plant C. dorycnium was collected from Tarhuna in Sidi Said area of Libya in May 2013. Plants belonging to Convolvulus genus contain various phytochemicals profiles. The focus of this study is on the phytochemical analysis of convolvulus dorycnium including phytochemical screening, extraction, isolation, and characterization. The phytochemical screening reveals the presence of flavonoids, tannins, saponins, steroids, carbohydrate, and coumarin in ethyl acetate and methanolic extract. Column chromatography and column chromatography and TLC were used to fractionate the ethyl acetate extract and H-NMR was used to elucidate the isolated compounds. Some compounds were isolated from the aerial parts of the plant; scopoletin, which is a phenolic coumarin (1) (7-hydroxy-6-methoxy coumarin), caffeic acid (2) (3,4-dihydroxycinnamic acid), and ferulic acid (3) (4-hydroxy-3-methoxy cinnamic acid) which are phenolic acids. The chemical constituents present in the extract have been reported to possess many biological activities
Mediterranean journal of pharmacy and pharmaceutical sciences
The purpose of the study was explored to find out the land and aquatic plyometric training on vital capacity among college men athletes. For the purpose of the study, forty five (n=45) men college athletes from Pudukkottai, Tamilnadu, India during the year 2019-2020 were selected as subjects. Their ages were from 18 to 21 years. The selected participants were divided at random into three groups of fifteen each (n=15). Group-I underwent land plyometric training, group-II aquatic plyometric training, and group-II acted as control group. The duration of the training period was restricted to eight weeks and the number of sessions per week was confined to five. The selected variable vital capacity was assessed by wet spirometer. The data were collected prior to and immediately after the training period of twelve weeks. The data obtained from the experimental groups before and after the experimental period were statistically analyzed with analysis of covariance (ANCOVA). Whenever the ‘f’ ratio for adjusted post test means was found to be significant, the scheffe’s post hoc test was applied to determine the paired mean differences. The level of confidence was fixed at 0.05 level for all the cases. The results of the study showed that aquatic plyometric training group is better than land plyometric training group and control group on improving vital capacity.
Recently, research capability has received an overwhelming and remarkable interest among academics and practitioners. This is timely since the Department of Education had institutionalized research and encouraged teachers to engage in it to support evidence-based practice, decision-making, policy, and program development. On these premises, a study was carried out to assess the research capability of public teachers in Malaybalay City, determine its correlates and determinants. It utilized descriptive, correlational, and explanatory designs. It administered survey questionnaires to 92 participants. Data were analyzed using descriptive and inferential statistics. The results revealed that teachers were slightly capable of conducting research and having neutral attitudes toward it, motivated to write research, had a high level of difficulties in research processes, and moderately capable of action planning. They also show evidence of potential in mentoring. Further, mentoring and action planning skills, motivation to write research, attitudes toward research, and the number of studies completed by teachers were the correlates of their research capability at different magnitudes of the relationship. Notably, the research capability of teachers had a low, negative but significant relationship with their age and accumulated years of service. Thus, this capability deteriorates as they age and accumulate years of service. The motivation to write research, the number of studies completed, and age were the determinants of research capability. It was concluded that research capability can be determined and predicted by how motivated teachers are to write research, how productive they are in research, and how young they are when they engage in this rigorous endeavor. The study identified and recommended topics for continuing professional development.
Kegiatan keagamaan merupakan kegiatan yang amat penting di MI Negeri 3 Jember, mengingat masih banyak peserta didik yang membutuhkan bimbingan guru untuk memiliki karakter yang sesuai dengan tuntunan Islam, di zaman teknologi initidak bisa dipungkiri bahwa anak-anak zaman sekarang sudah mengenal yang namanya internet. Maka dari itu pendampingan orang tua dan guru sangat dibutuhkan dalam perkembangan anak-anaknya. Salah satu pendidikan yang diajarkan guru kepada peserta didiknya sejak dini adalah pengajaran tentang al-Qur’an.Oleh karena itu darus keliling (darling) merupakan kegiatan yang tepat dalam proses membelajarkan al-Qur’an dalam rangka menanamkan karakter religius kepada peserta didik. Fokus penelitian yang dikaji adalah: Bagaimana peran guru sebagai pembimbing dalam menanamkan karakter religius peserta didik melalui kegitan ekstrakurikuler darus keliling (darling) di MI Negeri 3 Jember tahun 2019? Penelitian ini memperoleh kesimpulan: Peran guru sebagai pembimbing dalam menanamkan karakter religius peserta didik melalui kegiatan ekstrakurikuler darus keliling di MI Negeri 3 Jember dalam hal ini adalah guru yang senantiasa membimbing anak-anak anggota darling untuk belajar al-Qur’an. Darling ini adalah sebuah wadah yang diberikan oleh guru untuk mengembangkan potensi peserta didik. Karakter religius pun terbentuk yakni sikap patuh dalam menjalankan agama Islam, misalnya membaca al-Qur’an. keliling di MI Negeri 3 Jember dalam hal ini menggunakan instrumen penilaian yang memiliki 3 aspekpenilaian yakni aktif, kurang aktif dan tidak aktif.
The study identified the level of competencies and the extent of professional development needs of kindergarten teachers in the Sultan Kudarat Division, during the school year 2019 - 2020. The study employed a descriptive method. The study involved 54 kindergarten teachers in the division in accomplishing the 12-item self-assessment instrument. Data were analyzed using descriptive statistics. The results revealed that kindergarten teachers have a high level of competencies in content knowledge and pedagogy, learning environment and diversity of learners, curriculum and planning, and assessment and reporting. These indicate that they possess almost all of the competencies of efficient teachers. Results further revealed a very high extent of professional needs in content knowledge and pedagogy and the learning environment and diversity of learners, while they had a high extent of professional needs in the remaining domains. Since they reported very high priorities in content knowledge and pedagogy and the learning environment and diversity of learners, these areas would be the main considerations in the crafting of a professional development plan.
Pedagogical leadership has become an emerging and essential debate in the field of educational administration and leadership. This was a result of the shift from the hierarchical type in the past to a more inclusive, collaborative, and participative leadership. Previous studies indicate the furtherance of the inquiry into pedagogical leadership since it is a work in progress. For this reason, a systematic literature review mapped the literature relevant to pedagogical leadership. The review drew the lines between the empirical and theoretical-conceptual contributions, including the methodologies considered in both contributions. The results have implications for a more robust theoretical-empirical model or framework of pedagogical leadership applicable to specific levels of education, especially higher education contexts. The study also implies applying pedagogical leadership in the team, at departmental and organizational levels. Results imply promoting the culture of pedagogical leadership.
Pod sucking bugs are the key impediments for the low productivity in India. Nymphs and adults of tur pod bug, Clavigralla gibbose (Spinola) suck the cell sap from the pods and cause loss of the grain. Because of its high fecundity and wide host adaptability, it is necessary to check its damage potential. For this purpose, an experiment on bioefficacy of insecticides against this insect was conducted in the laboratory-cum-field conditions on cultivar “Paras” during kharif season 2010-11, 2011-12 and 2012-13. Eight insecticides viz., endosulfan 35EC, monocrotophos 36SL, chlorpyriphos 20EC, quinalphos 25EC, triazophos 40EC, decamethrin 2.8EC, fenvalerate 20EC and cypermethrin 25EC were selected based on their LC50 values against this insect. Among the tested insecticides, cypermethrin proved most toxic (63.94 times) against adults of C. gibbosa followed by decamethrin. Quick knock down effect of decamethrin and fenvalerate was recorded in the field conditions. Therefore, the combinations of decamethrin and quinalphos with DDVP (76 EC) were also tested under field conditions. Cypermethrin, decamethrin plus DDVP, decamethrin and monocrotophos were found effective in managing the C. gibbose population upto 10 days after application. None of the insecticides could manage the bug population below ETL after 14 days of their application. Application of cypermethrin @ 188 mL ha-1 recorded the highest grain yield, highest net monetary returns and highest incremental cost benefit ratio, followed by decamethrin, fenvalerate and monocrotophos. Either of dimethoate or oxydemeton methyl could also manage the bug population
Stem cells hold great promise for tissue regeneration and have the potential to treat many incurable degenerative diseases. Cancer stem cells (CSCs), or cancer initiating cells, have the ability to self-renew and differentiate into heterogeneous lineages of cancer cells. Current stem cell therapies face limitations, such as limited stem cell sources, time consumption, tumor formation, and immune rejection upon allogeneic transplantation. Allogeneic stem cell treatments simplify stem cell manufacturing and reduce transplant time, but their therapeutic potential is limited by human leukocyte antigen (HLA)-matched donors. CSCs retain characteristics essential for tissue regeneration. However, several limitations hinder cancer stem cell reprogramming with pluripotent factors. The development of 3D culture models for tissue imitating extracellular matrix in cancer cell lines aims to enhance CSC enrichment. This mini-review focuses on a new strategy for treating incurable degenerative diseases involving in vitro and in vivo 3D cancer models and the induced differentiation of CSCs into mature normal cell types. This allows tissue survival without immune rejection and offers a safe alternative to cancer stem cell reprogramming with pluripotent factors. In conclusion, preservation and banking of allogeneic CSCs offer an alternative, readily available, and safe strategy that can be used to facilitate stem cell-based cell therapy.