This article explores the increasing prevalence of mental health disorders and the pivotal role of Artificial Intelligence (AI) in diagnosis and treatment. It highlights how AI enhances diagnostic processes, continuous monitoring, and personalized mental health care experiences. The piece showcases examples of AI applications in detecting signs of mental illness through speech and video analysis, emphasizing improved accuracy for conditions like depression, Post-traumatic stress disorder PTSD, Attention deficit hyperactivity disorder ADHD, and Autism spectrum disorder ASD. Additionally, it discusses AI's role in continuous monitoring, prediction, and addressing the shortage of psychiatrists globally. The article concludes by introducing AI-based apps designed to assist individuals in managing depression, serving as complementary tools in collaboration with healthcare professionals. Overall, it underscores the transformative impact of AI on mental healthcare, offering innovative solutions for more effective, personalized, and accessible support.

Dhruvitkumar talati

Purpose: Congenital hypogonadotropic hypogonadism (CHH) is a rare genetic disorder mostly characterized by gonadotropins release and/or action deficiencies. Both isolated (idiopathic hypogonadotropic hypogonadism) and syndromic (Kallmann) forms are identified depending on the olfactory ability. Clinical and genetic heterogeneities of CHH have been widely explored, thus improving our understanding of the disease's pathophysiology. This work aims to (1) provide a detailed clinical and hormonal description of normosmic CHH patients and (2) identify the mutation linked to the studied phenotype. Participants and methods: We investigated three affected patients with normosmic CHH, belonging to a consanguineous Tunisian family. Patients underwent an insulin-induced hypoglycemia test. We performed whole exome sequencing to identify the causal mutation. Results: At first diagnosis, a total gonadotropic deficiency was identified in all patients. The insulin-induced hypoglycemia test has also revealed a reduced cortisol secretion and complete growth hormone deficiency. At 20.8 years, one female exhibited a spontaneous recovery of the hypothalamic-pituitary-adrenal axis function, unlike her affected siblings who still depend on corticosteroid replacement therapy. Herein, we identified a novel homozygous nonstop mutation (c.1195T>C) in KISS1R gene in all affected subjects. This mutation led to the substitution of the physiologic stop codon by an arginine (p.X399R). Conclusions: Our study highlights the importance of the KISS1R signaling, in gonadotropin-releasing hormone neurons, in the control of reproductive function. Additionally, our data suggests a complex central and peripheral metabolic control of puberty, through the hypothalamic KISS1R signaling. We suggest a mutual link between the hypothalamic-pituitary-gonadal, -adrenal, and -somatotropic axes.

Mariam moalla

The present study aims to shed some light on the gains from consolidation exercise in terms of profitability of banks. Through the application of paired t-test, we arrived at the result that the consolidation of banks did improve the profitability of banks in India. The increase in profitability of banks under study is due to an increase in employee turnover and the subsequent reduction in operating expenses. Merger and acquisition programmes in Indian banks cannot be regarded as a false step if the benefits of it accrue to all stakeholders.

Akhil antony

Family businesses must harness the full potential of their human resources and maintain employee loyalty to achieve the companies’ objectives effectively. This study examines the influence of transformational leadership on employee commitment through work-life balance and workplace social support. The research was conducted from August to December 2023 using an online questionnaire distributed to employees in a family firm in Medan, Indonesia. The data were then analyzed using PLS-SEM. The results show that transformational leadership significantly effects employee commitment, work-life balance, and workplace social support. However, although workplace social support mediates the relationship between transformational leadership and employee commitment, work-life balance fails to do so. It was also found that work-life balance has no direct influence on employee commitment. Using an IPMA analysis, this study highlights the importance of transformational leadership and workplace social support in the family business environment. Transformational leadership has also been shown to have the best performance and effect on employee commitment. Managers should prioritize these aspects to reduce employees’ stress levels, improve psychological well-being, and increase job satisfaction, leading to a more committed, high-performance workforce.

L

The international opioid crisis highlights the important role of pharmacists in prevention, using their availability and drug knowledge to prevent abuse. In this study, the knowledge, attitudes, and practices of Mangalore pharmacists towards preventing opioid abuse were assessed. From February to March 2025, a cross-sectional survey was done among 203 pharmacists aged 18-46 years in Mangalore using a pre-tested structured questionnaire. Data were analyzed using the Chi-square test, and thematic analysis of qualitative feedback. Pharmacists showed high knowledge, with 93.6% identifying opioids' mechanism as binding to CNS receptors correctly, 78.8% identifying naloxone's role in reversing overdose, and 70.0% knowing prescription drug monitoring programs' usefulness. Attitudes were optimistic, with 92.6% considering patient education a primary responsibility, 92.1% identifying multiple visits to the pharmacy as misuse, and 93.1% supporting medication-assisted treatment. The practice was active, with 93.1% checking prescription drug monitoring programs for suspected misuse and 69.0% advising take-back programs, but 43.8% associated early refills with misuse. Mangalore pharmacists show strong knowledge, attitudes, and practice against opioid abuse, being very strong in education and medication-assisted treatment support but having voids in misuse detection (for example, recognition of early refill) and naloxone confidence. Stronger training, better prescription drug monitoring program access, and policy adjustments can enhance their role in India's opioid strategy. Pharmacists are presented as front-line champions of opioid misuse prevention in this study, with implications for localized harm reduction.

Mediterranean journal of pharmacy and pharmaceutical sciences

This paper addresses global supply chain management (GSCM). The industry used to explore this topic is the automotive industry, as it is a core industry in the world economy, both in revenue generation and inefficiency. The paper explores both the positive and negative attributes of supply chain management, explores and analyses the gap between evaluation and implementation of improvements in supply chain management and then looks into the global issues affecting supply chain management and their solution.

Mohamed sorogy

The Quantum Teaching learning model is a modification of the various interactions that exist in and around the moment in learning. This study aims to find out more about how to apply Quantum Teaching in measuring students' abilities including cognitive, affective and psychomotor aspects. This research method uses qualitative research methods with the type of research field research. Data collection techniques using observation techniques, interviews, and documentation. While the data analysis is a qualitative analysis model of Miles and Huberman and Saldana which consists of data collection, data condensation, data presentation and drawing conclusions. The results of this study are: (1) Implementation of Quantum Teaching in Class V Thematic Learning at MI Mambaul Ulum Kandangrejo cognitive aspects, namely students are able to think more critically and broadly, students are able to do assignments or exercises and can understand learning well, students able to provide questions and answers properly and appropriately. (2) Implementation of Quantum Teaching in Class V Thematic Learning at MI Mambaul Ulum Kandangrejo aspects in the affective aspect, namely: the curiosity of students increases, students become more focused, students' attitudes become more confident and courageous. (3) Implementation of Quantum Teaching in Class V Thematic Learning at MI Mambaul Ulum Kandangrejo psychomotor aspects, namely: students are able to practice well the learning media is provided, students are able to name the names and parts of the circulatory organs, students are able to show the circulatory organs blood using the medium.

Educare: journal of primary education

This article addresses the implementation of the new generalized (G'∕G)-expansion method to the Caudrey–Dodd–Gibbon (CDG) equation and the Lax equation which are associated with the fifth-order KdV (fKdV) equation. The method works well to derive a variety of standard and functional closed-form wave solutions with distinct physical structures, such as, soliton, kink, periodic soliton, and bell-shaped soliton solutions. The solutions obtained using this method are useful and adequate than other methods. In order to understand the physical aspects and importance of the method, the attained solutions have been simulated graphically. The extracted results definitely establish that the new generalized(G'∕G)-expansion method is an effective mathematical tool to work out new solutions to different types of local nonlinear evolution equations emerging in applied science and engineering, but this method is not effective in solving nonlocal equations.

Md khorshed alam

This paper examines the influence of empowerment on job satisfaction in five-star hotels in Jordan. The influence of empowerment on job satisfaction remains a relatively unexplored area. A 52-item questionnaire, measuring empowerment and job satisfaction, was distributed to 332 employees in 12 five-star hotels in Jordan with a 56% response rate. Principal components analysis determined the factor structure and regression analysis determined the influence of empowerment on job satisfaction. The results revealed both structural and psychological empowerment have significant individual influences on job satisfaction, but more significant when structural and psychological empowerment are combined. Most of previous studies were conducted in western economies and little in the Middle East generally and Jordan in particular. This research contributes to the literature by including both dimensions of empowerment where previous scholars used only one.

Mukhles m. al-ababneh

Since October 17, 2019, Lebanon has experienced unprecedented popular protests, demanding the departure of the entire political class, accused of being gangrened by corruption. Country paralyzed, institutions closed for more than two weeks, the eyes are turned to universities that have closed their doors but whose community (teachers and students) actively participate in the national jump. This study explores the use of social media by universities in Lebanon during the national revolution using social big data technology on Twitter in comparison to the national usage of twitter. Important information was collected, analyzed and visualized using the R language.

Katia raya

Libya is a country with a great scholastic minds and intellectuals. They have some older universities like Al-Fateh University, Tripoli, Al-Arab Medical University, Benghazi or Garyounis University and Libyan International Medical University (Private). Some of the courses conducted by these universities were recognized throughout the world. With civil unrest and the devastation created by the internal conflicts had dented the whole country affecting education to a great extent. Educational institutions are the pillars who build responsible citizens with social and economic commitment. The recent reporting of the decline in the standard of education in world rankings have affected many intellectual minds including faculty from different universities of Libya. The ranking is not a reflection of the standard and standing of many university members belonging to all the faculties including humanities, science and medicine. It will be wise to introspect and reflect the status of education and the role of University in the upliftment of the standard of education.

Mediterranean journal of pharmacy and pharmaceutical sciences

Because of globalisation's intense change and competition pressure, businesses are driving from the company's dimension of individual management to collaborative cooperation approaches aided by the anticipated business strategy. A business strategy is a decision or action of a business or organisation to attract customers and achieve the organisation's objective. These strategies are the master plan for securing a competitive position of the firm market area of the competitors. Through business strategies, organisations will carry their business operations and fulfill the customers' desires and demands. Multination organisations and firms establishing subsidiaries and business entities in international markets or foreign countries must adopt different strategies during the integration process. The macro-economic and intercultural factors are the epicenter for change and must be considered in complex ventures. In the modern competitive market, multinational firms must collaborate and communicate with the partners, suppliers and customers through a complicated and temporary product supply chain. Business strategies involve complex processes requiring information on the diverse sources that need simultaneous changes by the managers of entrepreneurs. I this report, I choose Tesla Inc or Tesla Motors to explore the key strategies they have anticipated to inherit the global motor vehicle sector within the past few decades. The organisation was founded in 2003 by a group of various engineers. Tesla Motors deal in the automotive industry and has transformed its services to the global society.

Zamzam abdelazim

Foreign bodies (FBs) in the scalp are a common incident following head trauma, especially in traffic accidents, and are detected in the early post-traumatic period. The persistence of these FBs may cause pain and paresthesia. We report a case of 41 years old man, whose victim it’s been 20 years of physical aggression, in which the victim was hit by a brick occasioning a frontal wound stitched at the time without sufficient exploration. Months later, the patient presented several episodes of a frontal scalp nodular lesion with pus leakage (Fig. 1). The lesions were only treated with local antibacterial agents. Four years before the patient consults at our level, he consulted a dermatologist who performed a removal of the skin lesion. Months later, the lesion reappeared. At our level the clinical examination suspected a bone lesion, so CT was performed. Brain imaging was strongly evoking bone tumors or osteitis (Fig. 2). The patient was operated on under general anesthesia. First, a carcinogenic removal of the scalp lesion was performed; then, when reaching the bone, hard red friable bodies well separated from proportionally healthy bone were found. Those findings raise suspicion of the presence of FBs nested in the bone from the first head trauma. Hence, a carcinologic removal of the affected bone was postponed, and simple curettage was performed (Fig. 3). The post-operative course was without complications. The histological study confirmed per-operative findings: Multiple stony FBs associated with inflammatory reaction especially lymphocytes around vessels and the FBs.

Karishma

This study aims to determine the process of implementing PJOK learning in limited face-to-face learning during the Covid-19 pandemic in class V MIN 2 Palangka Raya City. This type of research is qualitative with case studies. Data collection techniques by observation and interviews. Meanwhile, data analysis uses descriptive data analysis. The results of this study show that:1) planning for sports and health physical education learning during the Covid-19 pandemic in MIN 2 Palangka Raya City: Teachers plan the PJOK class V learning program, develop the Annual Program, carry out Semester Program activities, carry out learning plans in the learning syllabus, distribute effective weeks.2) Implementation of Sports and Health Physical Education learning in MIN 2 Palangka Raya City, namely: development of the Annual Program into the Learning Implementation Plan, carrying out Semester Program activities, implementation of learning plans in the learning syllabus, online teaching, and learning process activities teachers explain teaching materials, apply learning methods.

Educare: journal of primary education

The wind tunnel experimental study has been carried out on a double delta wing of different geometrical configurations such as 80°/45°, 75°/45° and 70°/45° sweep angles given as Model I, Model II and Model III with various freestream velocities from 10 to 40 m/s with a step of 10 m/s in Hindustan Institute of Technology and Science, Chennai, Low Speed Wind tunnel (HITSLSWT). The experiment is conducted for the measurement of lift and drag forces using single component force balance. The investigation was done to look into the effects of changing the double delta wing's leading edge sweep angles. Three differentmodels have been tested at various angles of attack ranging from0° to +16° and 0° to −16° with 4° and four different freestream velocities based on the delta wing’s chord. It is observed that the influence of variation of leading edge sweep angles affects the performance of aerodynamic characteristics of themodel. The increase in angle in attack with increased velocity gives better aerodynamic performance. This paper provides good insight into the aerodynamic force measurement of double delta wing and the low-speed performance of the models.

Boopathy govindarajan

Multimedia data encryption attempts to prevent unauthorized disclosure of confidential multimedia information in transit or storage. Security of multimedia files attracts more and more attention and many encryption methods have been proposed in literature. If we call a multimedia data stream (message) plaintext , the process of transforming the plaintext into unintelligible data stream is referred to as multimedia encryption (MME) where the encrypted message (data stream) is often named ciphertext. The process of transforming the ciphertext back into plaintext is termed decryption. We propose a new block cipher based on randomized key of size n × n where n is the block size and the block undergoes n 2 iterations with the plaintext. Every iteration generates the pseudo cipher text. The encryption process generate the ciphertext C with the help of the randomized key. The decryption apply the key in reverse order on the cipher text, to get back the plain text. This work deals with the problem of efficient multimedia data encryption.

S arul jothi

The significance of fermentation is gaining more relevance due to the need for better preparation of plants, the desire for better plant constituents, and the aim for the preservation of medicinal plants. Hence, this study sets out to determine and compare the pH, proximate composition, chemical constituents, antioxidant, and antimicrobial effects of 3-day and 7-day fermented seeds of Nigella sativa. The fermentation of the seed was done for 3 and 7 days using 2.5% sugar. The pH of the sample declined from 3.5 to 3.45 during the fermentation. The proximate composition (moisture, ash, lipid, protein, and carbohydrates) was higher for the 3-day fermented sample while fiber was higher for the 7-day sample. The phytochemical constituents (tannins, saponins, phenols, alkaloids, flavonoids, phytates, oxalates, terpenoids, steroids, and glycosides) were higher for the 3-day than the 7-day sample. The Gas Chromatography-Mass spectrometry technique showed peaks that were characterized as 17 and 20 constituents on days 3 and 7 of the sample, respectively. The antioxidant capacity (ranging from 35.50% to 82.69% for the 3-day and from 37.50% to 84.99% for the 7-day sample) varies by the increasing concentration (7.81 mg/mL to 1000 mg/mL) of the sample. The diameter of zones of inhibition tested at different concentrations (25 mg/mL, 50 mg/mL, and 100 mg/mL) showed varying degrees of activity against Proteus vulgaris and Staphylococcus aureus. The zones obtained were higher 8-10 mg/mL against Staphylococcus aureus and 10-12 mg/mL against Proteus vulgaris for the 7-day fermented sample while 8.0 to 9.0 mg/mL was obtained for the 3-day fermented against Staphylococcus aureus and 8.0 to 10.0 mg/mL against Proteus vulgaris. Overall, the results of this study indicated that fermentation contributed to enhancing the bioactive components and antioxidant capacity of the fermented seeds of N. sativa thereby supporting the use of fermentation in the production of value-added functional foods.

Mediterranean journal of pharmacy and pharmaceutical sciences

Development of thematic teaching materials based on Islamic values, especially those related to the contents of the verses of the Alqur'an and / or hadith as the basis of all science. In the available books, there are no thematic teaching materials that are integrated with the Al-Quran and Hadith, as well as Islamic values ??that are able to implement the core competencies of the 2013 curriculum, namely the competence of spiritual attitudes in thematic learning. The formulation of this research is: (1) producing thematic teaching materials based on Islamic values ??theme 7 (Leadership) class 6 Madrasah Ibtidaiyah Negeri 2 Jember. (2) to determine the effectiveness of thematic teaching materials based on Islamic values ??in learning. This study uses a research and development research type, the Borg and Gall model which is divided into 10 steps, namely: (1) research and data collection (2) planning, (3) product draft development, (4) initial field trials, ( 5) revising the results of trials, (6) field trials, (7) improving products from field tests, (8) conducting field trials, (9) improving product results, and (10) disseminating and implementing. The testing technique was carried out by comparing the pre-test and post-test values. The data was calculated using the t-test and processed using the SPSS application to determine the effectiveness of teaching materials. The results of this study indicate: the validation test produces an average of 88.79% with the criteria that the book is very suitable for use in learning. In terms of attractiveness, this book is very interesting to use for students, this is based on the results of the questionnaire data given to students with an average of 88.24% with very attractive qualifications. Meanwhile, from the results of the pre-test and post-test based on the t count which shows that it is greater than the t table, it means that the book is effective for use in learning. Pengembangan bahan ajar tematik berbasis nilai keislaman, terutama yang terkait dengan isi ayat Alqur'an dan/atau hadits sebagai dasar dari semua sains. Dalam buku yang telah tersedia tidak ada bahan ajar tematik yang terintegrasi dengan Al-Quran, dan Hadits, serta nilai-nilai Islam yang mampu mengimplementasikan kompetensi inti dari kurikulum 2013 yaitu kompetensi sikap spiritual dalam pembelajaran tematik. Perumusan penelitian ini yaitu: (1) menghasilkan bahan ajar tematik berbasis nilai keislaman tema 7 (Kepemimpinan) kelas 6 Madrasah Ibtidaiyah Negeri 2 Jember. (2) mengetahui efektifitas bahan ajar tematik berbasis nilai-nilai keislaman dalam pembelajaran. Penelitian ini menggunakan jenis penelitian pengembangan Research and Development, model Borg and Gall yang terbagi menjadi 10 langkah, yaitu: (1) penelitian dan pengumpulan data (2) perencanaan, (3) pengembangan draf produk, (4) uji coba lapangan awal, (5) merevisi hasil uji coba, (6) uji coba lapangan, (7) penyempurnaan produk hasil uji lapangan, (8) uji pelaksanaan lapangan, (9) penyempurnaan produk hasil, dan (10) diseminasi dan implementasi. Teknik uji coba dilakukan dengan membandingkan nilai pre-test dan post-test. Data dihitung dengan uji-t dan diolah menggunakan aplikasi SPSS untuk mengetahui efektifitas bahan ajar. Hasil penelitian ini menunjukkan: uji validasi tersebut rata-rata menghasilkan 88,79 % dengan kriteria bahwa buku tersebut sangat layak untuk digunakan dalam pembelajaran. Dari segi kemenarikan, buku ini sangat menarik untuk digunakan pada siswa, hal ini berdasarkan dari hasil data angket yang diberikan kepada siswa dengan rata-rata 88,24% dengan kualifikasi sangat menarik. Sedangkan dari hasil pre-test dan pos-test berdasarkan uji t hitung yang menunjukan lebih besar dari t tabel, berarti buku tersebut efektif untuk digunakan dalam pembelajaran.

Educare: journal of primary education

: About 12% of the world population is affected by different forms of urolithiasis, the recurrence rate of which is 47-60% in females and 70-80% in males. According to WHO, 75% of people rely on traditional medicines to prevent and cure different ailments. Similarly, the majority of the world population uses several plants to treat problems related to the urinary tract system, of which urolithiasis is the primary cause. The review aims to collect data on the plants used in different parts of the world and cultures against urolithiasis, including their parts, mode of preparation, dosage, and administration. A literature review was conducted for traditionally used antiurolithiatic plants. The articles mentioning plant, parts, mode of preparation, dose and route of administration were selected. This information was extracted to compose Mono and Polyherbal antiurolithiatic formulations used in Appalachia (a region in the Eastern United States), Canada, India, Iran, Israel, Italy, Jordan, Latin America, Pakistan, Turkey and Yemen. The review provides essential data about plants used as antiurolithiatic in different parts of the world. The information is not only useful for ordinary people but also for the scientific community to carry out further phytochemical, pharmacological and toxicological studies for discovering new, effective, safer molecules against urolithiasis.

Dr. salman ahmed

The current study was conducted to determine the insoluble, soluble, and total dietary fiber content of Macrotyloma uniflorum (Lam.) Verdc., Phaseolus lunatus Linn. , and Phaseolus vulgaris Linn. , and legume flours by using AOAC enzymatic-gravimetric analysis. The results showed that M. uniflorum, P. lunatus, and P. vulgaris legume flours contained 155.91, 120.01, and 90.80 mg/g insoluble dietary fiber, respectively. At the same time, soluble dietary fiber was not found in any tested sample.

Dr. salman ahmed