Vitamin D deficiency is a public health concern affecting many individuals as it is highly prevalent in all parts of the world. Recent studies have reported an association of vitamin D deficiency with cardiometabolic alterations such as dyslipidemia. The study aimed to evaluate vitamin D and lipid profile levels among the Libyan adult population and investigate the correlation of vitamin D deficiency with the alteration of lipid profile levels. A cross-sectional study was conducted at Janzour Hospital among 193 subjects (107 males and 86 females) whose ages ranged between 20 and 50 years over three months from Sept to Dec 2023. Vitamin D, cholesterol, triglyceride, low-density lipoprotein, and high-density lipoprotein levels were estimated. The total mean vitamin D levels were 8.31±4.74, 23.83±2.78, and 42.67±7.95 ng/dl for deficiency, insufficiency, and sufficiency, respectively. The findings revealed significant alterations in cholesterol (increase), triglyceride (increase), LDL-cholesterol (increase), and HDL-cholesterol (decrease) among subjects who had vitamin D deficiency or insufficiency as compared to subjects having vitamin D sufficiency. Vitamin D levels were negatively correlated with cholesterol, triglyceride, and LDL cholesterol, and they were positively associated with HDL cholesterol. The incidence of dyslipidemia is higher in the vitamin D deficiency group than in the insufficiency and sufficiency groups. It is essential to frequently monitor lipid profiles among vitamin D-deficient individuals to avoid subsequent disorders or damages associated with the alterations of lipid profile patterns.
Mediterranean journal of pharmacy and pharmaceutical sciences
This study aims to examine and compare the levels and patterns of aggressive behavior among higher secondary students in rural, semi-urban, and urban areas. Aggression among adolescents is a significant concern, and understanding its variations across different settings can provide valuable insights for intervention and prevention strategies. The study employs a review-based research design, using articles published between 1993 and 2023 to collect data on aggressive behavior of higher secondary students. For this purpose, a review of the literature was performed by using the search words “aggressive behavior”, “higher secondary students”, “rural”, “semi-urban”, “urban” in the databases like Google Scholar, ResearchGate, Academia, Shodhganga, PubMed, JSTOR and Elsevier for articles. The results will shed light on the prevalence, types, and potential factors influencing aggression in these areas, informing the development of targeted interventions and policy recommendations and statistical analyses will be employed to examine the relationships between variables. Importance and Scope of the Topic: Aggressive behavior is a topic that affects us all. From playground bullies to road rage enthusiasts, aggressive behavior has a significant impact on our daily lives. Understanding the causes and consequences of aggression is crucial in finding ways to prevent and manage such behavior. After all, the world would be a much better place if we all knew how to calm down and express our frustrations in healthy ways.
Hemolytic uremic syndrome (HUS) is a microangiopathic thrombotic disease, which is classified into atypical, typical, and secondary types. Thrombocytopenia, acute kidney failure, and hemolysis are the main features of HUS regardless of its type. Infection with Shiga toxin-producing Escherichia coli causes typical HUS, and gene mutations trigger atypical HUS, while secondary HUS is associated with bone marrow transplantation, autoimmunity, cancer, and other diseases. New insights into the pathogenesis of HUS have emerged over the past decades, suggesting an important role of the complement system in disease pathogenesis, which has been reinforced by the efficacy of plasma exchange and monoclonal antibodies in its treatment. In this review, we performed an updated review of HUS with a focus on understanding its pathogenesis.
Flow control techniques are broadly classified into two types 1.passive control 2.active control. Present paper discuss about the experimental investigation of flow control using passive method on bluff body. Authors also explains about the various flow control techniques used in bluff body aerodynamics. Experimental setup consists of L m span and diameter d of cylinder model. The next model is having strip of cross section 0.01d dia is placed on the cylinder along the span wise distance with equal polar distance around 30o. both the models were kept between four walls in a Reynolds number ranging from 10000 to 15000. The results show that the Cp values changes according to the changes in cylinder roughness.
Intensively cultivated rice-wheat cropping system of the Indo Gangetic plain (IGP) is a potential source of greenhouse gas (GHG) emissions.Agriculture sector emits GHGs like methane (CH4) and nitrous oxide (N2O). The total amount of GHGs emitted by a product is known as its carbon footprint (CFP).Quantification of CFP of crops will help in identifying management practices to reduce CFP of crop production. Studies related to assessing of CFP of agricultural products are lacking. The present review paper was aimed to discuss about the studies done on GHG emission from rice-wheat cropping system of the Indo Gangetic plains. The paper elaborates on what is CFP, how to calculate CFP of rice-wheat cropping system with the help of different case studies. The paper provides insights about certain agricultural management practices which can help in reducing CFP of rice-wheat cropping system. Discussion from this paper signifies the importance of carbon footprint assessment in maintaining the sustainability of rice wheat cropping system.
pecial Needs Education (SNE) highly plays a crucial for all those children and adults with disabilities. In this article, I aim to research the awareness levels of SNE in various schools and communities in the city of Hyderabad, India. A qualitative approach was taken for this purpose. My research also includes a case study of a special needs child along with his family and academic background, in order to know the degree of awareness among parents.
Background: Pandemics are known to cause poor mental well-being and an increased risk of mental disorders. The foremost concern emerging from different aspects of COVID-19 is its impact on mental health. There were many surveys conducted on the general population related to the effect of COVID-19 and few studies on its psychological impact but there is sparse literature on how the containment measures affected the psychiatric patients. Objective of the study was to investigate whether the COVID-19 related lockdown affected the subjective mood and behavior of psychiatric patients and their caregivers. The secondary purpose is to assess the difficulties encountered in procuring medicines and the effect of non-availability of homoeopathic medicines if any. Methods: A cross-sectional survey was conducted on mentally ill patients and their care-givers in the Outpatient Department of Psychiatry in National Homoeopathy Research Institute in Mental Health (NHRIMH), Kottayam. Respondents were evaluated with a specially framed questionnaire containing 22 questions to assess the effect of lockdown on psychiatric patients and their caregivers, who attended the OPD after the COVID-19 related lockdown. The data generated through the study are analysed and presented in this article. Results: Out of the total 548 participants (M-65.9%, F-34.1%) who responded to the survey, 290 (53%) cases expressed that they were distressed to be under lockdown. 26.5% of the clients reported worsening of mental health conditions during lockdown compared to pre-lockdown. 54.2% of the patients found difficulty in procuring homoeopathic medicines during Lockdown. Conclusions: Authorities should consider the ways of limiting the effects of confinement on mentally ill patients and their caregivers by developing strategies to mitigate the adverse consequence of the pandemic.
The analgesic activity Of the crude hexane and ethanol extracts of the leaves and male flowers of Luffa cylindrica (L.) Roem., (sponge gourds) was carried out at dose of 500 mg /kg b.w., (p.o.) in mechanically induced pain in rats by using analgesy-meter. These extracts produced significant analgesic effect results of the present study revealed the analgesic properties of the leaves and male flowers of Luffa cylindrica.
Penelitian ini bertujuan untuk melihat seberapa besar dampak kualitas produk, persepsi konsumen dan brand image terhadap keputusan pembelian produk endorsement pada masyarakat di Medan dengan menggunakan word of mouth sebagai variabel moderasi. Sampel penelitian ini adalah sebesar 100 orang responden dengan teknik analisis data menggunakan analisis jalur (path analysis). Hasil dari penelitian ini menunjukkan kualitas produk, persepsi konsumen dan brand image berpengaruh terhadap keputusan pembelian produk endorsement pada masyarakat di Medan. Lebih lanjut, word of mouth tidak memoderasi kualitas produk terhadap keputusan pembelian dan juga tidak memoderasi persepsi konsumen terhadap keputusan pembelian namun word of mouth memoderasi brand image terhadap keputusan pembelian produk endorsement bagi masyarakat di Medan.
Salinity is a major environmental stress which has been studied extensively and has its impact on agriculture in the past, present and future. The global importance of salt affected soils can be explained by their wide distribution on all continents covering about 10% of the total land surface. At present, there are nearly 954 million ha of saline soils on earth’s surface. It is extremely difficult to quantify the social and economic costs of salt prone land and water resources. Plant Growth Promoting Rhizobacteria (PGPR) is a group of bacteria that actively colonize plant roots and increase plant growth and yield. They play an important role within the interaction between soil and plant. As plants grow on marginal soils such as saline soils, the importance of the rhizobacteria increases as they mobilize nutrients and provide tolerance ability to the plants. In the present study, an attempt was made and isolated 51 PGPR isolates (Phosphate Solubilizing Bacteria–18; Azotobacter spp.-16 and Azospirillum spp.-17) from different salt affected areas in Tamil Nadu and Puducherry. All the isolates were screened for their efficacy against different sodium salts namely sodium chloride, sodium citrate and sodium sulphate. It was observed that the absorbance of the culture broth grown in salt stress to sodium chloride decreased with increasing concentration of the salt. Similarly decrease in growth pattern in terms of the absorbance was also observed in salt stress to sodium citrate and sodium sulphate.
Carpal tunnel syndrome (CTS) is caused by the shortening of the median nerves in the wrist, resulting in hand pain and paralysis necessitating surgical operation for relief. Conventional open carpal tunnel release (CTR) procedures, involving long incisions, often lead to complications, delaying patients' recovery for weeks or months. Therefore, mini-incision surgery has emerged as a preferred option, offering reduced pain, smaller wounds, and improved appearance. This study aimed to compare the outcomes of modified mini-incision surgery for CTS before and after the operation. It was a retrospective study involving 80 patients, with data collected from medical records pre-and post-operation, specifically at the 2 nd week, 3 rd month, 6 th month, 12 th month, and 24 th month intervals. Variables included operation time, incision length, pinch strength, gripping strength, two-point discrimination (2-PD), visual analogue scale (VAS), Levine score, quick disabilities of the arm, shoulder and hand (Quick-DASH), wound pain, and pillar pain. Data were analyzed using descriptive statistics and logistic regression, with a significant level of 0.05. The mean incision length was 11.54 mm. At the 2-week post-operative mark, the pinch strength was 5.43, gripping strength was 14.96, 2-PD was 5.84, the VAS score was 2.86, the Levine symptom was 3.84, and the DASH score was 69.43. There was a relationship (p-value<0.05) between preoperative and postoperative measures for pinch strength, gripping strength, 2-PD, and Levine symptom condition. The study on 80 patients who underwent modified mini-incision surgery for CTS at Naresuan University Hospital in Phitsanulok, Thailand, found that these parameters showed significant improvement postoperatively. Patients demonstrated good recovery and condition 2 weeks after the mini-incision surgery for CTS.
The wind tunnel experimental study has been carried out on a double delta wing of different geometrical configurations such as 80°/45°, 75°/45° and 70°/45° sweep angles given as Model I, Model II and Model III with various freestream velocities from 10 to 40 m/s with a step of 10 m/s in Hindustan Institute of Technology and Science, Chennai, Low Speed Wind tunnel (HITSLSWT). The experiment is conducted for the measurement of lift and drag forces using single component force balance. The investigation was done to look into the effects of changing the double delta wing's leading edge sweep angles. Three differentmodels have been tested at various angles of attack ranging from0° to +16° and 0° to −16° with 4° and four different freestream velocities based on the delta wing’s chord. It is observed that the influence of variation of leading edge sweep angles affects the performance of aerodynamic characteristics of themodel. The increase in angle in attack with increased velocity gives better aerodynamic performance. This paper provides good insight into the aerodynamic force measurement of double delta wing and the low-speed performance of the models.
The orientation he/she chooses has a bearing on his/her long-term success. This orientation is known as your "locus of control." Its study dates back to the 1960s, with Julian Rotter's investigation into how people's behaviours and attitudes affected the outcomes of their lives. Locus of control has been defined as the degree to which an individual perceives having control over the environment (Rotter, 1966). According to Rotter (1975), there are two types of control, internal and external, which anchor a continuum that approximates a normal distribution. People are said to have an internal locus of control when they believe reinforcements are contingent upon their own behaviour or stable personal characteristics. External locus of control results when people believe that reinforcements are due to luck, fate, or powerful others outside of their control. Current study focuses on investigating the influence of demographic variables (age, gender, education level), marital status and socio economic status (occupation, income) on the level of internal/ external locus of control with the help of data collected from residents (aged between 20 and 50) of a select suburbs in Mumbai city. On analysing the data so collected, it is found that age has a major influence on an individual’s level of internal locus of control.
The soil samples were collected from Melia dubia plantations in two different locations in Tamil Nadu. A total of twenty five actinomycetes isolates were isolated and they were screened for melanin pigment production using different culture media. Only two isolates were able to produce melanin pigment under in vitro study and one isolate showed positive reaction to L-tyrosine substrate. Based on morphological and bio-chemical characters the isolate was identified as Streptomyces sp. The DNA of the isolate was isolated and its 16S rDNA gene was amplified and sequenced. The phylogenetic analysis of Streptomyces puniciscabiei was carried out.
Our society is reflected through the media, which represents what society is like and how it functions. The sole medium that serves to keep people informed is media, whether it is written, electronic, or on the web. It also serves to amuse, educate, and inform the audience about current events. Our society's voice is now dominated by the media. A number of media platforms have brilliantly stirred the views of the younger generation and other segments of our society. The study's goal is to examine the media's involvement and efficacy throughout the demonetization process. The study's major goals are to look into the role of the media in informing people about the demonetization process and its consequences. The study will contribute to a better understanding of the role of the media in conveying information on significant problems and how individuals learn about current events. In Lucknow's South City and Eldeco neighborhood, a poll of 300 persons was held. The researchers devised a data gathering interview plan that took into account the function and type of media in raising public awareness. The convenience sampling method was used in the research investigation. The study focuses on media consumption patterns and behaviour throughout the demonetization period.
Experimental and numerical investigation have been done to evaluate the aluminum agglomerate size in AP/HTPB/Aluminum propellants and compared it with burning rate results. Bimodal AP particle size distribution is considered in the present work. The effect of aluminum size, aluminum content, fine AP size, fine AP/binder ratio and coarse AP size in aluminum ignition, accumulation and agglomerate formation during combustion, typically in their ranges, are focused. The burning rates were found to be higher for the propellants with lower fine AP/binder ratio. The agglomerate sizes for the propellants with 10 % Al was found to be higher than those with 15 and 18 % aluminum. Observing the agglomerate sizes and the burning rate trends, it can be concluded that the agglomerate sizes vary inversely as the burning rates.
The drug-drug interactions (DDIs) are actions or events that occur when two or more drugs administered together, may cause a clinical significance or not. There are certain factors that may affect the severity of DDIs such as age, gender, number of drugs prescribed, and physician specialists. This study aims to answer: Is there DDI in Libyan community pharmacies? In addition, to explore the factors that might be affecting DDI. Drug Interactions Checkers are used. 200 prescriptions were collected randomly from two different areas ( high and low income),100 from each one and were used to investigate the DDIs by using two different sources (Drugs.com and BNF platforms), bearing in mind, age, gender, prescribers’ specialty, and drug number (prescription size). A personal interview questionnaire with pharmacists for investigate a source of DDI knowledge was considered. The correlation test was used to analysis the findings. The randomly selected sample has 316 drug combinations. The study has revealed a minimum of three drugs (46.0%). In general, Drugs.com was the richer source of DDI than BNF (66.5% and 34.5%, respectively). It is found that 66.5% (67.0% of this is moderate DDI) of these combinations have DDI by Drugs.com. A significant correlation between DDI and gender (male > female, p = 0.035) was found. In a state of residential areas, the results are similar in both selected pharmacies. Most moderate DDIs (21.0% and 15.0%) are prescribed by orthopedics and psychiatrists, respectively. The observational interview questionnaire indicated that 100% of the participating pharmacists had no source of knowledge regarding DDI, 100% of 200 prescriptions had no chick it regarding DDI and 100% of found DDI is released to use by community pharmacies to patients. More than half of the prescribed drug combinations have DDIs (classified as moderate DDIs), and all of them are released for use by pharmacists.
Mediterranean journal of pharmacy and pharmaceutical sciences
Kegiatan belajar mengajar siswa disekolah yang berpusat pada guru mengakibatkan siswa hanya menerima mata pelajaran secara pasif pembelajaran yang seperti ini mengakibatkan siswa kurang berminat dalam mengikuti pembelajaran tematik,proses pembelajaran yaitukurang maksimal pelaksanaan proses pembelajaran yang diterapkan sehingga peserta didik kurang menarik dengan pembelajaran dan metode yang sebelumnya, Sehingga berpengaruh kepada pemahaman siswa. Berdasarkan latar belakang Fokus dalam penelitian ini adalah 1)Bagaimana Perencanaan metode Rol Playing pada pembelajaran tematik di Madrasah IbidaiyahDarul Ulum Sukorambi Jember tahun pelajaran 2018/2019? 2)Bagaimana Pelaksanaanmetode Rol Playing pada pembelajaran tematik di Madrasah Ibidaiyah Darul Ulum Sukorambi Jember tahun pelajaran 2018/2019? 3) Bagaimna evalusai Metode Role Playingpada pembelajaran tematik di Madrasah Ibidaiyah Darul Ulum Sukorambi Jember tahun pelajaran 2018/2019? Hasil dari penelitian ini adalah: Perencanaan metode Role Playing pada pembelajaran tematik di kelas IV yaitu: dengan menyusun Program tahunan, program semester, silabus dan RPP(Rencana Pelaksanaan Pembelajaran) dan dikembangkan dalam RPP dengan menggunakan metode Role Playing sehingga setiap siswa dapat memahami materi yang telah dipelajarinya.
This proposed work is used to optimize the costs of exceptional elements of machine cells for a variety of components in changing environments to have reduced material movements in cell layout. The exceptional ele¬ments are eliminated in the optimization model by doing machine duplication and part subcontract. Then the shop floor layout is designed to have optimized material movements between cells and within a cell. The result of a linear programming optimization model is cost savings, machines duplicated, parts subcon¬tracted, inter intracellular movements. Finally, the output of the inbound facility design is the floor layout which has machine cell clusters with optimized floor areas. The optimization model is provided with budg¬etary constraints for duplication and the economic tradeoff between machine duplication and part subcontract. Cell layout is prepared to reveal the saving in floor area and material movement lengths than in process layout with the help of distance matrix and dimensions of cells.
People management is a very significant facet for organizations to keep up with competition. At the sme level, talent management is not a smple human resource terminology that one comes across. The concept of talent management requires the human resource to hire, manage, develop, and retain a productive workforce. Indeed, companies that employ talent management stay competitive through systematic and consistent decisions about worker development. The study outlines the proposal’s hypothesis or questions, literary analysis relevant to the topic, theoretical frameworks, and advantages and disadvantages of the applicable frameworks.