Analgesic and antiinflammatory potential of verbesina encelioides in rodents

Verbesina encelioides, a plant with a rich history in traditional medicine, is commonly known as golden crownbeard or cowpen daisy. Despite its widespread use, scientific validation of its therapeutic potential, particularly its analgesic and anti-inflammatory effects, remains limited. Our study is designed to comprehensively evaluate the analgesic and anti-inflammatory effects of methanol extracts from various parts (leaves, stems, flowers, and roots) of V. encelioides in animal models. Acute toxicity, antinociceptive effects (heat plate and tail flick tests), and anti-inflammatory activity (carrageenan-induced inflammation) were tested in Swiss albino mice and Wistar albino rats. The acute toxicity assay showed no adverse effects in mice up to 1000 mg/kg, a highly encouraging result. In analgesic studies, V. encelioides extracts showed dose-dependent increases in reaction times similar to aspirin. Different extracts had different effects on paw edema in anti-inflammatory testing; some at first increased inflammation but eventually showed significant decreases, especially at higher dosages. These results offer a positive perspective on V. encelioides' possible medicinal use. These results provide a positive perspective on Verbesina encelioides' possible therapeutic use. The results imply that extracts from the plant, which are abundant in bioactive substances such as flavonoids, phenolics, and alkaloids, may have applications in treating pain and inflammation. These results highlight the plant's medicinal potential and suggest that more research and development could help address pain and inflammation naturally.

Dr. Salman Ahmed Dr. salman ahmed

Estimation of oxalate contents in macrotyloma uniflorum (lam.) verdc., phaseolus lunatus linn., and phaseolus vulgaris linn

The seed flours of Macrotyloma uniflorum (Lam.) Verdc., Phaseolus lunatus Linn., and Phaseolus vulgaris Linn. were investigated for their total, soluble and insoluble oxalate contents by HPLC. The total oxalate content of Macrotyloma uniflorum, Phaseolus lunatus and Phaseolus vulgaris were 1.24, 1.77 and 1.71 mg/ g, respectively. The % age of soluble oxalate was Macrotyloma uniflorum (19.50), Phaseolus lunatus (15.08) and Phaseolus vulgaris (15.88). The calculated soluble oxalate: calcium ratio of all tested legume flours is lesser than one and hence will not create any resistance in calcium bioavailability.

Dr. Salman Ahmed Dr. salman ahmed

Analgesic and antiemetic activity of cleome viscosa l.

The seeds of Cleome viscosa are used in traditional systems of medicine for the treatment of many diseases in Asia. This study evaluated fixed oil from the seeds of Cleome viscosa for analgesic and antiemetic activity by using the acetic acid induced writhing test in mice (intraperitoneally) and chick emetic model (oral treatment) respectively. The results showed significant analgesic and antiemetic activities of Cleome viscosa fixed oil.

Dr. Salman Ahmed Dr. salman ahmed

Comparison of branded and non-branded food samples widely consumed in north india with reference to trans fatty acid content

Trans fatty acids (TFA) are the geometrical isomers of monounsaturated and polyunsaturated fatty acids that affect the functional and physicochemical properties of these fatty acids, which in turn affect their metabolism in humans. Since the database available for trans fatty acids in food from India is scarce, the research report generates data about trans fatty acid content in selected foods popular in north India. In this report, various food samples like cookies, chocolates, biscuits, pizza, fries, indigenous snacks like samosa, pakora and indigenous sweets like jalebi, gulab jamun, and laddoo were analyzed for the Trans Fatty Acid (TFA) content by gas chromatography. A large variation was found in trans fatty acid content among these food samples. The results also showed that only 4.5% of the samples were found to contain TFA less than 0.5% while approximately 8% of samples having more than 5% TFA (1 branded and 6 non-branded samples). Also, a large variation was found in the trans fatty acid content of branded and non-branded food samples with the mean value of TFA in branded and non-branded food groups as 1.781 and 6.125 respectively and the t-value of 0.852 between the two groups. When regulations are emphasizing on labelling the TFA content on the product, there are arrays of unlabelled products which are not governed under any regulations. Hence there is a need for strong food regulations to bring levels of trans fats in processed foods to negligible levels.

Shalini Purwar Shalini purwar

Research project - talent management as a strategic priority for the company

People management is a very significant facet for organizations to keep up with competition. At the sme level, talent management is not a smple human resource terminology that one comes across. The concept of talent management requires the human resource to hire, manage, develop, and retain a productive workforce. Indeed, companies that employ talent management stay competitive through systematic and consistent decisions about worker development. The study outlines the proposal’s hypothesis or questions, literary analysis relevant to the topic, theoretical frameworks, and advantages and disadvantages of the applicable frameworks.

Zamzam Abdelazim Zamzam abdelazim

Employment, employability, and competencies of the bachelor of secondary education graduates

Tracing graduates has become an imperative for higher education institutions much more during the pandemic. This tracer determined the employment and employability status of the 2019 BSE graduates and identified the competencies they adequately acquired and deemed vital for work. It used descriptive design, and data were collected from the 103 graduates through a Google form with open and closed-ended questions administered between November and December 2020. Results revealed that most of the graduates had been employed in teaching and teaching-related jobs but mostly in contractual arrangements within the first and second six months after graduation. Many had their first jobs with meager salaries from the private sector. Communication, pedagogy, information communication technology, time management, and flexibility were the top competencies they adequately acquired and were beneficial in work. The study concluded that these graduates had acquired 21st-century skills in their respective degree programs. These results have corresponding implications for future research in confirming the most employable skills in secondary teaching. As recommended, classroom instruction might emphasize the development of these skills. Eventually, these become the competitive advantage and employability capitals of future graduates. Administering the licensure examination and the release of its results can be done within the first three months after graduation to lessen the cost of waiting.

Manuel Caingcoy Manuel caingcoy

Improving public hospital efficiency and fiscal space implications: the case of mauritius

Background General Government Health Expenditure (GGHE) in Mauritius accounted for only 10% of General Government Expenditure for the fiscal year 2018. This is less than the pledge taken under the Abuja 2001 Declaration to allocate at least 15% of national budget to the health sector. The latest National Health Accounts also urged for an expansion in the fiscal space for health. As public hospitals in Mauritius absorb 70% of GGHE, maximising returns of hospitals is essential to achieve Universal Health Coverage. More so, as Mauritius is bracing for its worst recession in 40 years in the aftermath of the COVID-19 pandemic public health financing will be heavily impacted. A thorough assessment of hospital efficiency and its implications on effective public health financing and fiscal space creation is, therefore, vital to inform ongoing health reform agenda. Objectives This paper aims to examine the trend in hospital technical efficiency over the period 2001–2017, to measure the elasticity of hospital output to changes in inputs variables and to assess the impact of improved hospital technical efficiency in terms of fiscal space creation. Methods Annual health statistics released by the Ministry of Health and Wellness and national budget of the Ministry of Finance, Economic Planning and Development were the principal sources of data. Applying Stochastic Frontier Analysis, technical efficiency of public regional hospitals was estimated under Cobb–Douglas, Translog and Multi-output distance functions, using STATA 11. Hospital beds, doctors, nurses and non-medical staff were used as input variables. Output variable combined inpatients and outpatients seen at Accident Emergency, Sorted and Unsorted departments. Efficiency scores were used to determine potential efficiency savings and fiscal space creation. Findings Mean technical efficiency scores, using the Cobb Douglas, Translog and Multi-output functions, were estimated at 0.83, 0.84 and 0.89, respectively. Nurses and beds are the most important factors in hospital production, as a 1% increase in the number of beds and nurses, result in an increase in hospital outputs by 0.73 and 0.51%, respectively. If hospitals are to increase their inputs by 1%, their outputs will increase by 1.16%. Hospital output process has an increasing return to scale. With technical efficiencies improving to scores of 0.95 and 1.0 in 2021–2022, potential savings and fiscal space creation at hospital level, would amount to MUR 633 million (US$ 16.2 million) and MUR 1161 million (US$ 29.6 million), respectively. Conclusion Fiscal space creation through full technical efficiency, is estimated to represent 8.9 and 9.2% of GGHE in fiscal year 2021–2022 and 2022–2023, respectively. This will allow without any restrictions the funding of the national response for HIV, vaccine preventable diseases as well as building a resilient health system to mitigate impact of emerging infectious diseases as experienced with COVID-19.

Ajoy nundoochan

Assess the prevalence of polycystic ovarian syndrome among adolescent girls.

World Health Organization (WHO) estimation disclosed over 116 million girls (3.4%) area unit stricken by PCOS worldwide. The predisposing risk factors embrace genetic science, system, lifestyle/environment, fatness that contributes to the event of PCOS. it's calculable that between 5 to ten % of U.S. girls of childbearing age have PCOS. that is regarding five million girls, which makes the condition one among the foremost common secretion endocrine disorders among girls of generative age. A study to assess the prevalence of PCOS among adolescent women at hand-picked setting, Chennai. Objective: to assess the prevalence of PCOS among adolescent women. Methodology: A non-experimental descriptive analysis style was adopted during this study. The non-probability convenient sampling technique was accustomed choose the sample size of two hundred adolescent Girls. The assessment of the prevalence of PCOS was administrated employing a self-reported check list through a Googletype. A survey link was sent to the respondents, via email and WhatsApp& teams. knowledge was analyzed by descriptive and inferential statistics. Result: our Majority (36.5%) of the samples had gentle & moderate PCOS symptoms and twenty-sevenths had severe symptoms. relating to physical activity, the bulk (38%) of the samples had gentle physical activity, thirty-fourth had moderate physical activity and twenty-eighth had severe activity. There was a direct correlation between PCOS symptoms and Physical activity. There was a statistically vital relationship between PCOS symptoms with age, religion, academic standing, dietary habits, previous information, supply of data, the cycle of emission and BMI and there was a statistically vital relationship between physical activity with age, Religion, academic standing, monthly family financial gain, age at the time of start, previous information, supply of data, variety of family, Cycleof emission & BMI. Conclusion: PCOS among adolescents is a rising problem that wants careful assessment, timely intervention, and appropriate treatment. Diagnosis of PCOS in adolescence remains a challenge attributable to overlapping symptoms of PCOS with traditional time of life changes in adolescents. life-style modifications for weight reduction and dietary modifications and psychological content plays vital role in these young ladies for preventing long run complications. Keywords: Poly cystic ovarian syndrome (PCOS), Prevalence, PCOS symptoms, Physical activity, Adolescent Girls.

Elsi Queen Elsi queen

Navigating adolescence with cystic fibrosis: a systematic review on impact of cystic fibrosis with teenagers

Cystic fibrosis is a challenging disease which creates many complications. The impact caused from cystic fibrosis on an adolescent is a challenging phase for their lives. Negative impacts like the society’s pressure, anxiety and depression are few common reasons that are being unspoken and ignored due to complexity of the disease. This study is aimed to identify the necessary gaps and educate the necessary policy makers and CF center health care team to have a better understanding about the context of the aftermath of cystic fibrosis and enhance better patient care. More over this systematic review also points out the main trends in this field of study. Qualitative study and quantitative are prominently used research methods to gain an understanding the about the gaps in the research. However, there is still a scarcity of quantitative and mixed research methods. Furthermore, limitations such as language, cultural influences were identified whilst going through the analysis. Overall through the information given in the following in this study more information regarding that warrants answers can be identified which will lead to proper care towards the teenagers who suffers from cystic fibrosis

Chanitha Pemasena Chanitha pemasena

Analgesic and anti-inflammatory effects of phaseolus vulgaris l. fixed oil in rodents

The seeds of Phaseolus vulgaris are known as common beans or kidney beans. The dry seeds are eaten as pulse and are enriched with protein, fiber, starch, B vitamins (B1, B6, B9), iron, potassium and selenium. Beans also contain about 1-2 % of fixed oil. Phaseolus vulgaris is linked to anticancer, antihyperlipidemic, hypoglycemic, and antioxidant actions. The fixed oil of Phaseolus vulgaris (PVFO) seeds is extracted with hexane and used in this study to assess acute oral toxicity, analgesic (by acetic acid-induced writhing, hot plate and tail flick tests in mice) and antiinflammatory (by carrageenan-induced paw edema in rats) actions. Four groups were made (n=6): Group-I: Normal Saline Control (2ml/kg), Group-II: PVFO (2ml/kg), Group-III: PVFO (4ml/kg) and Group-IV: Standard Acetylsalicylic acid (ASA 300 mg/kg). PVFO in 2ml/kg and 4ml/kg doses demonstrated analgesic and anti-inflammatory activities, but in hot plate, results were unreliable as significant activity started after 90 minutes. A 5ml/kg dose was administered orally in mice for a toxicity test, and no toxicity symptoms were observed. Therefore, PVFO is safe for oral use up to 5ml/kg and may possess analgesic and anti-inflammatory actions.

Dr. Salman Ahmed Dr. salman ahmed

Research article list & database

This is a non-inclusive collection of my published articles.

Mostafa Eissa Mostafa eissa

The implementation of total quality management (tqm) in the hotel industry

This study sets out to explore the Critical Success Factors (CSFs) necessary for Total Quality Management (TQM) implementation in hotels. It also aims to classify participating hotels into groups based on their TQM adoption by using cluster analysis. A quantitative survey method was applied. Data were collected from a sample of managers from four- and five-star hotels in Jordan, 170 questionnaires were distributed to managers and 104 usable questionnaires were returned. The findings revealed that TQM is existed and implemented in the hotel industry. The researcher then confirmed that four- and five-star hotels can be classified into two groups, namely, “high TQM adopters” and “low TQM adopters”.

Mukhles m. al-ababneh

Curbing food insecurity through composite blend in the production of bread from wheat, acha, uzaaku and unere flours

The aim of this study was to evaluate the proximate and micronutrient composition, physical, biochemical and sensory properties of the bread produced from blends of wheat, acha, uzaaku and unere composite flours. Six samples (A-F) were produced in the following ratios A= 100:0:0 (100% Wheat), B= 80% wheat flour, 10% acha, 5% uzaaku flour, 5% unere; C = 70% wheat flour, 10% acha, 10% uzaaku flour, 10% unere; D = 60% wheat flour, 15% acha, 15% uzaaku flour, 10% unere; E = 50% wheat flour, 20% acha, 15% uzaaku flour, 15% unere; F = 40% wheat flour, 20% acha, 20% uzaaku flour, 20% unere. The parameters were analyzed using standard methods. The proximate composition of the bread showed significant increase (p<0.05) in protein, fat, crude fibre, ash, and caloric (energy) value which ranged between 7.69-18.32%, 2.41-3.70%, 2.473.86%, 3.09-4.03%, and 285.25-304.06 (Kcal/kg) and a significant decrease (p<0.05) in moisture content (20.72-26.14%) and carbohydrate (49.37-58.20%), respectively. The micronutrient content showed increase in calcium, magnesium, potassium, iron, zinc, phosphorus, vitamin B1, B2, B3, A and C as the amount of substituted flour blends increases. The result of the physical properties showed decrease in the loaf weight, loaf height, loaf volume and specific volume ranged from 240.60-218.80 g, 3.33-6.66 cm, 155.00-205.00 cm3, 0.71-0.85 cm3/g, respectively. The result of the serum biochemical parameters of rats fed the composite bread samples showed significant decrease (p<0.05) in AST, ALT, ALP, Bilirubin, creatine, urea and albumin values, respectively. The sensory attributes of the bread showed significant differences (p<0.05) in colour, aroma, taste, crumb texture and general acceptability such that the values obtained ranged from 6.05-8.90, 6.008.45, 6.40-8.60, 5.85-8.30 and 6.10-8.35, respectively. The findings of the study showed that supplementation of wheat with 10% acha, 10% uzaaku and 10% unere flour blends could produce well accepted bread samples.

OKECHUKWU OBED CHUKWUEMEKA Okechukwu obed chukwuemeka

Sulphate and chloride resistance of vermiculite blended concrete

In the construction industry lot of natural sand is being used in the preparation of concrete. Levels of natural sand are depleting day by day. The cost of natural sand is also increasing every day. Therefore, there is a need for alternative materials to natural sand. In this study, exfoliated vermiculite is replacing natural sand partially. Vermiculite at 5%, 10%, and 15% is used for replacement. The concrete cubes are cast for M 30 grade to determine the optimal percentage of replacement of natural sand by vermiculite. In this study, coarse aggregate used includes both normal aggregate and recycled aggregate. The water-cement ratio of 0.45 is adopted. The durability tests conducted include the sulfate resistance Test and the chloride resistance test. The cost analysis was also done and results are presented. The test results are promising when vermiculite was used to replace natural sand at 10%.

Kiran kumar narasimhan

Performance analysis of various parameters of network-on-chip (noc) for different topologies

Network on a chip is a concept in which a single silicon chip is used to implement the com-munication features of large-scale to very large-scale integration systems. For high-end System on Chip de-signs, Network on Chip is considered the best integrated solution. NoC has several advantages over dedicat-ed wiring and buses i.e. increased bandwidth, low latency, less power consumption and scalability. Reduc-tion in the latency (end-to-end latency and network latency), loss probability, energy consumption and re-sponse time are the basic parameters which are considered by the researchers for the optimization of the networks-on-chip topologies. In this paper we review the most popular technologies and also some recent topologies for interconnection networks. We study their performance and summarize their strengths & weakness.

Ashish mulajkar

Regional disparities in covid-19 vaccine distribution: a global analysis of manufacturer contributions and product availability

The unprecedented global effort to develop and distribute COVID-19 vaccines has highlighted remarkable scientific achievements and persistent inequities in access across populations. Analyzing of regional vaccine deployment patterns reveals critical insights into pandemic response dynamics, shaped by manufacturing capacity, regulatory frameworks, procurement strategies, and regional health priorities. Data from WHO regions (Africa, the Americas, Eastern Mediterranean, Europe, and Western Pacific) demonstrate significant disparities in vaccine types and suppliers, underscoring the complexity of global vaccination efforts. (Figure 1) illustrates this regional vaccine distribution by WHO regions.

Karishma Karishma

Challenges faced by teachers of learners with learning disability

This Research Paper elucidates the challenges faced by teachers while teaching learners with learning disability. This has been conducted as a research study by the Research Scholar which explores multifaceted aspects of ‘challenges based on the responses given by the participants in the interview. It is a study designed to identify multifaceted dimensions of challenges faced by teachers while teaching learning disabled children. The research study analyzes the impact of challenges on teachers and how they are overcoming these challenges. This descriptive study was carried out as qualitative research under an Indian scenario based on Primary data available on the subject. The research enquiry focused on several research questions: What is the teacher’s understanding of learning disability? What challenges do remedial teachers face while teaching children with learning disability and how do they overcome them? What are the teaching approaches and methodology used to teach children with learning disability? The study will try to highlight the challenges faced by teachers to address them in front of the school administration. The challenges faced by teachers while teaching learning disabled children, i.e., ‘Teaching material and Curriculum structure’, ‘Behavioural issues’, ‘Lack of time’, ‘Parental expectations and Parental issues’, ‘Motivation’, ‘Self-esteem’ and ‘Emotional issues. The methods used to overcome these challenges were pointed out and analyses. Each teacher was using their own methods to tackle these challenges but some methods were used generally and an individual tailored method were developed and used according to respective learners.

Hashir Ahammed A V Hashir ahammed a v

Implementasi strategi cooperative learning tipe jigsaw dalam pembelajaran akidah akhlak kelas v min bangka belitung pontianak

Penelitian ini dilatar belakangi oleh adanya permasalahan yang terjadi pada MIN Bangka Belitung Pontianak seperti guru kurang melibatkan siswa dalam materi pembelajaran, guru cenderung menyampaikan materi dengan menggunakan metode ceramah tanpa adanya variasi sehingga menyebabkan kejenuhan dalam belajar, guru kurang memahami dalam tentang memilih dan menentukan strategi cooperative learning tife jigsawyang tepat sehingga berdampak pada terciptanya proses pembelajara yang lebih baik. Penelitian bertujuan untukmengetahui: perencanaan, langkah-langkah, dan evaluasi dalam pembelajaran Materi Aqidah dengan Strategi Cooperative Tipe Jigsaw dalam pembelajaran Akidah Akhlak Materi Sikap pada guru di Kelas V MIN Bangka Belitung Pontianak Tahun Pelajaran 2017/2018. Hasil penelitian ini dapat disimpulkan bahwa Perencanaan Strategi Cooperative Learning Tipe Jigsawdalam Pembelajaran Akidah Akhlak Pada Materi Akhlak Tercela di Kelas V MIN Bangka Belitung Pontianak dengan lebih baik dan siswa lebih aktif dalam proses pembelajaran; langkah-langkah strategi cooperative learning tipe jigsaw dalam materi sikap siswa di sekolahdi kelas V MIN dibagi menjadi 5 kelompok, setiap kelompok diksih materi pembelajaran, dan siswa mendiskusikan dengan materi tersebut; Pelaksanaan evaluasi proses dan hasil kegiatan pembelajaran yang menggunakan langkah strategi cooperative learning tipe jigsaw dalam materi sikap siswa di sekolahdi kelas V MIN Negeri Bangka Belitung Pontianak adalah menggunakan tes tertulis dan tes lisan juga mengunakan penilain proses dari observasi siswa saat proses pembelajaran atau setelah mata kuliah selesai.

EDUCARE: Journal of Primary Education Educare: journal of primary education

Evaluation of multiple-choice and short essay questions in pharmacology education

Multiple choice questions (MCQs) and short essay questions (SEQs) are common methods of the assessment of medical students in courses of pharmacology. Poorly constructed test items (questions) are a widespread problem resulting in failure to assess learning objectives. It has been reported that there are 36.0% to 65.0% flawed test items in medical education assessment tools. Thus, the objective of this study was to evaluate MCQs by determining the item writing flaws (IWFs) and to evaluate the SEQs by determining the cognitive level of each item. Four pharmacology tests were administered to third-year pharmacy students at Department of Pharmacology, Faculty of Pharmacy, Omar Al-Mukhtar University, Bayda, Libya. These were evaluated by determining the IWFs and the level of the cognitive domains. Based on Buckwalter’s modification of Bloom’s taxonomy cognitive level, for the SEQs, 30.0% of the questions were attempted to check recall of information, 26.0% were attempted to evaluate understanding and interpretation of data and 43.0% of the questions were attempted to check the application of knowledge for solving a particular problem. For the MCQs, 94.6% of the questions were attempted to evaluate the understanding and interpretation of data. For the IWFs, there were more than 40.0% of flawed questions. The most common writing flaws were the negative stem (47.4%), unfocused item (16.0%), non-homogenous in grammar and contents (10.0%), all the above (10.0%) and clang association (05.0%). In a short essay, the SEQs were of excellent quality because they were equally distributed among the three levels of cognitive (level I, II and III). On the other hand, the most common mistakes IWFs of the MCQs were the negative stem (47.0%) and the idea was not clearly and concisely stated in the stem (16.0%). This study concludes that questions in SEQs are valid to measure the learning objective but MCQs were not in pharmacology courses in Libya.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

Globalization and chinese higher education

The cross line movement according to the two labor and products is the thing to take care of in the present worldwide economy. Worldwide exchange labor and products has for some time been a standard, for different advantages that gather from it. There have been numerous respective and multilateral arrangements comparable to cross line exchange dealings. The development of administrations area that decidedly influences the everyday daily routine and guidelines of experiencing or personal satisfaction. The World Trade Organization (WTO), of which in excess of 156 nations are individuals, has an understanding according to global administrations exchange. The General Agreement on Trade in Services (GATS) is the WTO's arrangement that administers exchange 12 sorts of administrations, including 'instruction administrations'. One of the basic inquiries or issues in such manner would be corresponding to the sort of college to be permitted to set up its grounds or branch or in any case offer training administrations. This paper would endeavor to give some potential experiences into this issue. Internationalization and globalization are the two Global ideas terms conversely utilized as far as higher education. Most impressively, the test to set up colleges will come from the worldwide monsters of the interchanges, data innovation and mixed media ventures worldwide suppliers, packed with capital, ready to get to remarkable global researchers and educators, talented in giving in situ understudy support at the same time in numerous nations, and equipped for expediting proficient accreditation and acknowledgment all throughout the planet. Quality in the subsequent 'worldwide virtual colleges' will be high, normalization will make cost structures that are powerfully serious, brand acknowledgment will be acquired, maybe by accepting one of the incomparable Ivy League organizations as an accomplice, or on the other hand by moving into advanced education a prevailing brand from the correspondences or processing ventures.

Dr Gedam Kamalakar Dr gedam kamalakar

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