The present investigation is an attempt to evaluate the analgesic and antiemetic activities of Ficus exasperata and Cleome ciliata leaves methanolic extract by using the chick emesis model (oral treatment) and acetic acid-induced writhing test (intraperitoneal treatment) in mice, respectively. The antiemetic activity (150 mg/kg b.w., of extract) was carried out by using chlorpromazine (150mg/kg) as standard antiemetic drug. The analgesic activity (250 mg/kg b.w. of extract) was performed using aspirin (150mg/kg) as a standard analgesic drug. The results showed significant analgesic and antiemetic effects.

Dr. salman ahmed

The decision of the government of India to allow foreign direct investment in higher education is based on a consultation paper prepared by the commerce ministry, which is marked by arguments, perverse logic and forced conclusions. FDI in any field does not have an attached objective of fulfilling social agenda of the welfare state. It is guided by profit and market. This would result in commoditization of education. As per past most foreign institutes invest in technical courses which market needs rather than in quality education and research which is important for creating and developing human resource. There is a shortage of funds in higher education sector. Here are not many ways in which this investment in this sector can be increased in this sector domestically. Since a large number of students go abroad for their higher education, it is sensible to allow foreign universities to set up their campuses here, in India. This would help in arresting the outflow of monetary and human capital. Further, foreign higher educational institutes would create competition with the local institutes making them internationally competitive this article examines the issues and financial compulsions, presented in the consultation paper

Dr gedam kamalakar

Marketing has now adopted technologies in the attempt to increase brand recognition. Due to the COVID-19 pandemic, many companies suffer, yet many even reap more profits, such as e-commerce. The purpose of this research is to figure out whether Celebrity Endorsement, Advertising Appeal, and Electronic Word of Mouth have influence towards customer’s Purchase Decision in one of popular e-commerce in Indonesia called Bukalapak. Through the non-probability sampling type, particularly purposive sampling approach, one hundred respondents are taken as samples. The method in this research is descriptive and causal, and the research type is quantitative research. The data analysis methods used are descriptive statistics, coefficient of correlation, coefficient of determination, linear regression analysis and hypothesis testing through T-Test and F-Test. The T-test shows that Celebrity Endorsement, Advertising Appeal, and Electronic Word of Mouth partially influence the Purchase Decision. The F-Test result shows that all independent variables simultaneously influence Purchase Decision. Out of all, Celebrity Endorsement has the biggest influence on Purchase Decision. The value of coefficient of determination obtained is as much as 80.6% indicating that the customer’s Purchase Decision in Bukalapak is explained by Celebrity Endorsement, Advertising Appeal, and Electronic Word of Mouth. The recommendation given is to ensure the company uses talented and well-known celebrity endorsers, design attractive and unique advertisement, and maintain satisfactory performance to encourage complimentary reviews on its platform.

L

During Movement Control Order (MCO) of COVID-19, many information has been disseminated through both traditional and social media. Some of that information was credible and came from reliable sources while other information was fake and included misinformation, disinformation, and infodemic. The people needed credible information rather than fake one in this critical time. This study aimed to explore the credibility of media, information sources, the main issues, and preferred communication patterns and method of works perceived by Malaysians during MCO. A total of 300 questionnaires were distributed, and 210 were returned. The results of this study showed that the majority of respondents 69% relied on new media as their main source of information compared to 30.9% who relied on traditional media. However, a total of 64.8% of respondents considered traditional media as more credible and accurate compared to 35.2% for new media. Additionally, the main concerns and issues followed by respondents on media were health, economic, social, education and others. Finally, a total of 55.7% preferred face to face communication compared to 44.3% who preferred online communication. A total of 51% of respondents preferred to work from the workplace or office compared to 49% who preferred to work from home. Television played a significant role during the pandemic period due to its high credibility as perceived by Malaysians. The main intriguing implication of this study is considering the traditional media as more credible than social media by the Malaysians although the social media was their main source of information.

Mohammed fadel arandas

Background: Pregnancy-related hormonal changes increase the risk of gingival inflammation and bleeding. Poor oral hygiene and dietary habits, such as frequent intake of sugary foods, may worsen this risk. Understanding the relationship between diet, oral hygiene, and gingival health in pregnant women is essential for improving prenatal care. This study aimed to assess dietary patterns, oral hygiene practices, and self-reported gingival bleeding among pregnant women attending the Mother and Child Hospital, Ondo, Nigeria. Methods: A descriptive cross-sectional study was conducted over four months among 216 pregnant women at the Mother & Child Clinic, University of Medical Sciences Teaching Hospital, Ondo, Southwest Nigeria. A structured, self-administered questionnaire collected data on sociodemographic characteristics, oral hygiene habits, perceived oral health conditions, and dietary patterns. Clinical oral examinations were conducted using the Oral Hygiene Index. Data were analyzed using SPSS version 25, with p < 0.05 considered significant. Results: Most participants (79.2%) were in their second or third trimester. Although 83.3% used toothbrushes and 52.3% brushed twice daily, 39.8% had poor oral hygiene, and 33.3% reported gingival bleeding. Despite 76.4% awareness of dental services, 53.2% had never visited a dentist. Most participants frequently consumed fruits (88.9%), vegetables (84.8%), and animal proteins (84.7%), while 43.0% consumed sugary drinks regularly. No significant association was found between dietary habits and gingival bleeding. Conclusion: The study revealed a clear awareness–behavior gap: good knowledge of oral health did not translate into optimal hygiene practices or dental visits. Poor oral hygiene remained common, and gingival bleeding was prevalent. Although most participants had healthy diets, sugary drink intake was still high. Diet alone was not protective against gingival bleeding. Promoting effective oral hygiene and integrating dental care into prenatal programs is recommended.

Karishma

Industrial waste is one of the most essential sources of contamination in the surface environment. Among different industries, tannery industry releases huge amount of pollutants into the ecosystem. Long term disposal of the tannery wastes has resulted in wide contamination of agricultural land and water sources in different parts of India. An attempt was made to study the diversity status of different microbial organisms in tannery effluent treated samples in Dindugal, Tamil Nadu. It was found that Electrical Conductivity (EC) and heavy metal contents were higher and population density of different beneficial microbes found better. Among different microbes isolated, phosphate solubilizing microbes (PSB) was found maximum which is followed by fungi and actinomycetes. The population density of non-symbiotic and symbiotic nitrogen fixers were found to be low in numbers when compared to other samples screened. Similarly, occurrence and distribution of AM fungal spores were also found low in heavy metal polluted samples as compared to the samples collected from non-polluted outside tannery effluent treatment area. Among different Arbuscular Mycorrhizal (AM) fungi, Glomus species was found to be dominant in the samples collected from outside tannery effluent treatment area as compared to tannery effluent samples.

Dr. saranya devi k

This study's objective was to determine the distribution of allele frequencies of CYP2C9 and CYP2C19 gene polymorphisms among the Papuan population, known as the second-largest ethnic group in Indonesia. According to recent research, there is a decrease in CYP2C9 and CYP2C19 produced by humans globally, including in Indonesia. These gene polymorphisms aid in the transmission of various endogenous and exogenous drugs in the human body. Material and Methods: A sum of 99 subjects, comprising 73 male and 26 female subjects aged 20-30 years, were used for this research. PCR-RFLP (polymerase chain reaction-restriction fragment length polymorphism) analysis using AvaII, NsiI, and SfaNI enzymes tested for the genotypes CYP2C9 and CYP2C19 administered. The distribution of genotypes was calculated in the population (P<0.05) using the Hardy-Weinberg equilibrium. The Faculty of Medicine Gadjah Mada University's Medical and Health Research Ethics Committee (MHREC) accepted this research with written consent. The results revealed that in Papua subjects, CYP2C9*2 (rs1799853) and CYP2C19*17 (rs12248560) alleles were absent while in 17 percent of the population CYP2C9*3 (rs1057910) allele frequency was. In conclusion, CYP2C9*3 has the highest polymorphism rate in Indonesia, with the absence of CYP2C9*2 and CYP2C19*17. Therefore, genetic drift can occur within this ethnic group.

Syahrul tuba

Analgesic activity on two Cleome scaposa and Cleome brachycarpa by applying pressure-induced pain model

Dr. salman ahmed

A simple one pot synthesis has been developed for the synthesis 1,4-dihydropyridine using an efficient and reusable silica supported MgO solid catalyst by condensation of dimedone, ethyl acetoacetate, aldehyde and ammonium acetate in methanol as a solvent at room temperature. The reactions could be carried out under mild reaction conditions with very good yield of polyhydroquinoline, up to 92%. This catalyst could be recycled very easily, which makes this methodology environmentally benign.

Shilpa sangle

Ultraviolet (UV) disinfection technologies are well-known tools for microbial prevention in indoor public places which are frequently employed for disinfecting air, surfaces, and water. Such technologies have drawn a great deal of interest due to its potential application, especially in the domain of healthcare. This article discusses the shortcomings of chemical disinfectants and analyzes the current research standing on the development of various types of UV disinfection technologies for their prospective usage in the healthcare industry. Furthermore, the article provides a thorough analysis and in-depth evaluation of the current antibacterial studies using UV lamps and light-emitting diodes (LEDs) for the treatment of frequently encountered pathogens associated with healthcare. According to the systematic review, UV-LEDs have shown to be a potential source for delivering disinfection which is equally efficient or more effective than traditionally used UV lamps. The findings also provide valuable considerations for potentially substituting conventional lamps with LEDs that would be less expensive, more efficient, more robust, non-fragile and safer. With greater effectiveness and advantages, UV-LEDs have shown to be the potential UV source that could fundamentally be able to transform the disinfection industry. Therefore, the study supports the employment of UV-LED technology as a better and workable approach for effective disinfection applications. The study also offers insightful information that will help to direct future studies in the domain of hygienic practices used in healthcare facilities.

Jahanzeb

India is not known as a country to be in for a bisexual person. Homosexual acts even within wedlock are a punishable offence in India. Legal battles over provisions in the Indian Penal Code which criminalizes any sexual act “against the order of nature” are rife. Even though Kerala has been hailed as a paradox inside India (mainly due to its human development parameters), the social, cultural and legal environment in the state is hostile to individuals who question hetero-normativity. Non-judgemental and unbiased scientific therapy or counselling are seldom available to sexual minorities. This paper is an attempt to map the experiences of a female who is openly bisexual, and is living in Kerala. An ethnographic interview was conducted where the experiences of the participant are explored, from the relationship dynamics as seen by her, to sexual experiences and difficulties in relationships. A reference is also made to the personal and social support systems that are in place for the Lesbian, Gay, Bisexual, Transgender (LGBT) community in Kerala and their role in initiating discourses regarding the topic. A few pointers for future studies in the topic, especially within the context of Kerala are also put forward.

Dr. chinchu c

Parkinson’s disease, first described by James Parkinson in 1817, is a neurodegenerative ailment resulting from the damage of nerve cells in the brain. It is a chronic, progressive, neurodegenerative disorder with an estimated prevalence of 31 to 328 per 100,000 people worldwide. It is estimated that more than 1 percent of the population over age 65 are afflicted with Parkinson’s disease; incidence and prevalence increase with age. There are numerous unanswered questions regarding the diagnosis and management of Parkinson’s disease. Worsening mobility, causing problems with activities of daily living, pain and communication problems due to rigidity of facial muscles, are the main reasons of their decreasing quality of life. This study is focused on the role of psychological variables, which could be associated with quality of life in PD patients. After their identification a discussion about opportunities of improvement patient’s quality of life can be opened. Current drug therapies for human PD with Levodopa or various dopamine receptor agonists offer symptomatic relief and appear to have little effect on the neurodegenerative process. More than 50% of patients with PD treated over 5 years with Levodopa will develop complications such as motor fluctuations and dyskinesia’s. In this scenario, slowing the progression of PD through neuroprotective or restorative therapy is a major focus of research. From a pharmacologic standpoint, current strategies involve interrupting the cascade of biochemical events that leads to death of dopaminergic cells. The significance of many indigenous medicinal plants and their phytoconstitutents in the management of Parkinsonism with minimal side effect profile arise in this context

Zeenath banu

Among the consequences of armed conflict, the effect on the mental health of the civilian population is one of the most significant aspect of psychiatric disorders. Studies of the general population show a positive increase in the incidence and prevalence of mental disorders. This study is aimed to determine the relationship of the national crisis on the mental health conditions of university students and their academic performance. Specifically, this study was aimed to evaluate the national crisis effects on the mental health and the academic performance as well as the association of the national crisis, mental health and academic performance. 40 sample size of pharmacy students at the academic year 2019-2020 at Attahadi University, Tripoli, Libya were used in this study and a survey of validated questionare for mental health was considered. The findings revealed that the effects of national crisis on the mental health of the students disclosed the verbal interpretation of rarely grade. Indeed it can be found that mental health of the students was not of greatly affected in this sample. The academic performance of the students disclosed that academic year levels one and three have verbal interpretation of good and academic year level two has fair. Though the academic performance of the students did not show a verbal interpretation of weak or very weak. It is still worthwhile to note that none of them has reached the very good and the excellent performance. It can be concluded that a need for the students coping strategies be enhanced for them to reach their maximum potential with their academic performance. This study shows also that a weak positive relationship among the variables. Though it’s not that high, indeed, the mental health of the students can be a predictor to their academic performance.

Mediterranean journal of pharmacy and pharmaceutical sciences

Green computing is focusing on reducing the energy consumption, resource usage, carbon dioxide emission. It was found that Last year, Google used about 12.4 terawatt-hours of electricity. Energy consumption in data centers is reduced by decreasing the resource utilization that is by switching off or shifting the computing nodes to sleep mode. But when the servers are being used the energy consumption is minimized by using energy efficient scheduling and optimization techniques.In WNS the sensor nodes are deployed in remote areas, these sensors are powered by battery that decreases the lifetime, therefore by using energy efficient techniques can increase the uptime of the battery-operated devices in WNS. This work studied various energy efficient techniques that minimize energy consumption usage in Data Centers (DC) and the algorithms that increase the uptime of the battery-operated device in (WNS) Wireless Network Sensors.

Dr h shaheen

 ABSTRACT Macrotyloma uniflorum, commonly known as horse gram, is an underused pulse that holds great potential as a supply of nutrition and functional compounds. This review paper aims to provide a comprehensive overview of the nutritional composition, Pharmacological activities, health benefits, and potential applications of Macrotyloma uniflorum. Horsegram has a high amount of protein, dietary fibre, and a variety of vital minerals and vitamins that make up its nutritional profile. Horsegram also has a high content of antioxidants, flavonoids, and phenolic compounds, all of which contribute to its potential health advantages. Horsegram intake has the potential to help manage a number of chronic conditions, including diabetes, obesity, cardiovascular problems, and gastrointestinal disorders, according to many studies. The review investigates the possible health advantages of Macrotyloma uniflorum, emphasising its function in controlling blood sugar, managing weight, lowering cholesterol, and antioxidant activity. Horse gram's medicinal potential is further increased by the presence of bioactive substances that include anti-inflammatory, antibacterial, diuretic, antiobesity, analgesic, anaphylactic action, and anticancer activities. In conclusion, this review paper presents a comprehensive evaluation of Macrotyloma uniflorum, highlighting its nutritional composition, health benefits, and potential applications. The findings underscore the significance of horse gram as a valuable functional food ingredient and encourage further additional investigation of its therapeutic properties for human health and well-being.

Asawari mansabdar

Monitoring and controlling of clean area environment is of paramount importance to ensure product safety and quality. This comprehensive analysis evaluates environmental monitoring (EM) data from Class C and Class D controlled environments in pharmaceutical manufacturing, utilizing Active Air (AA), Passive Air (PA), and Contact Plate (CP) or Replicate Organism Detection And Counting (RODAC) surface samples. The study aims to identify contamination trends, anomalies, and compliance with ISO 14644-1 and EU GMP Annex 1 standards. Results reveal unexpected findings: Class C Active Air (43 CFU/m³) and RODAC (3 CFU/plate) overall averages are higher than Class D Active Air (34 CFU/m³) and RODAC (2 CFU/plate), respectively, deviating from expected cleanroom classification. Class D Passive Air (22 CFU/plate) is higher than Class C (17 CFU/plate), aligning with expectations. Persistent hotspots were identified in Class C (e.g., location labelled “AA C 12 NG0”AA averages± Standard Deviation (SD): 67.33±17 CFU/m³), indicating localized control failures, while Class D showed extreme individual spikes (e.g., AA D 99 Ac: Max 171 CFU/m³). Sporadic contamination events in Class C suggest transient breaches, necessitating root-cause investigations. The study also highlights limitations of Class D monitoring, which obscures temporal trends and risks missing critical excursions due to long intervals between samples. Recommendations include targeted engineering assessments for high-load zones, enhanced Standard Operating Procedures (SOPs) for cleaning and gowning, adoption of real-time biofluorescent particle counters to replace manual sampling, and increased monitoring frequency in Class D hotspots.

Mostafa eissa

The present study focused on analysing the FDI inflow in Electronics industry form year 2007 to 2018 in country and role of FDI in development of the electronic industry in India. As well identify the current status of Electronics industry in world and the share of India in the same. The present research work also attempted to take overview of various policies introduced by Government of India to promote the FDI in Electronics industry. The FDI inflows statistics reveals that the separate category of Electronics sector is created in year 2007 by DIPP for recording FDI inflow. And sector specific data published in DIPP factsheet revels that this industry has attracted 0.55 % of total cumulative FDI inflow in country till December 2018 which is very negligible share of overall FDI in country. The overview of policies revels that NPE–2012 to New NPE-2018 had attempted to provide multiple incentives for Foreign Investors to establish their electronic manufacturing facilities in country but very negligible response has been seen in response of the same. Further results of study reveals that due to various FTA’s & being signatory of WTO’s ITA-1 in year 1996 leads toward reducing competitiveness of electronic manufacturing in India and country become net importer of approximately 50% of overall domestic need of electronics products.

Anshuman vijay magar

Background: The legume pod borer, Helicoverpa armigera (Hübner), is one of the most damaging crop pests, including pigeonpea. Host plant resistance is a component of pest management and therefore, we standardize a nylon bag No-Choice Bioassay technique to screen for resistance to H. armigera under field conditions. Methods: Pigeonpea plants were infested with 24 h old 1, 2, 3, 4 and 5 larvae per plant inside the nylon bag. Observations were recorded on pod damage, larval survival, larval weight, pupation, adult emergence, and fecundity after 10 days. Result: Pigeonpea varieties AL-201, H03-41 and PAU-881 exhibited lower pod damage (15.89 to 19.77%) and larval weight (12.02 to 13.82 mg). The expression of resistance to H. armigera was associated with trichome density, pod wall thickness and higher amount of phenolic compounds and condensed tannins. Lower trichome density and thin pod walls and higher amounts of sugars rendered the varieties Paras, Manak and Pussa-992 more susceptible to H. armigera. Nylon bag assay can be used to screen and select pigeonpea cultivars for resistance to H. armigera.

Dr. babu lal jat

Purpose of this study is examining the cause of stress among selected private banking employees. Stratified sampling method was used to carry out the data collection. For this employee of various private banks were chosen. A questionnaire with 12 items with dichotomous (Yes-1, NO-2) were developed and tested for reliability and prior to the distribution of questionnaire. 253 respondents were selected from various private banks in Mysore district, Karnataka state India. The survey questionnaire was sent via email, requesting to complete it. The questionnaire includes 11 demographic information’s and statements to measure. Chi-Square analysis was carried out to examine the cause of stress among employee using SPSS21. We found that designations have significant influence on employee and The other factors of do not have any significant influence on employee. Therefore we concluded that in private banks demographic variable such as designation creates stress in all aspects. Future research should consider a larger sample from leading sectors where job natures are similar. Analysis should be more rigorous, where Amos could be used for analysis.

Dr manjunatha m k

Macrotyloma uniflorum, commonly known as horse gram or kulthi bean, is grown as a pulse for livestock and human consumption. The beans contain about 1.3% fat, 18% protein, 15% carbohydrate, and vitamins and minerals. Traditional medicine uses it as an antihyperglycemic, antioxidant, antihypertensive and diuretic. Other important medicinal uses include the treatment of renal stones, obesity, piles, oedema and fever. The present study evaluated analgesic (by acetic acid-induced writhing, hot plate and tail flick tests in mice) and anti-inflammatory (carrageenan-induced paw oedema in rats) activities of Macrotyloma uniflorum fixed oil (MUFO). Four groups were included in the study: Group I: Normal Saline Control (2ml/kg), Group II: MUFO (2ml/kg), Group III: MUFO (4ml/kg), and Group IV: Standard Acetyl salicylic acid (ASA 300mg/kg). All results were significant; however, the tail flick and paw oedema tests observed a delayed onset of action. The oil's acute oral toxicity was also checked in mice and was found safe up to a 4ml/kg dose, as no signs of toxicity and mortality were observed. It is concluded that Macrotyloma uniflorum fixed oil may possess analgesic and anti-inflammatory activity, which can be related to a peripheral mechanism of action.

Dr. salman ahmed