The present study is designed to determine the types of secondary metabolites in three selected seed powders using a fast, reliable, and non-destructive Near Infra Red spectroscopic analytical technique. NIRS analysis of Macrotyloma uniflorum (Lam.) Verdc., Phaseolus lunatus Linn., and Phaseolus vulgaris Linn., seed flours were used to qualitatively evaluate secondary metabolites. The fine powder of crude drug was directly applied to FOSS XDS near the infrared Rapid Content Analyzer. The adequately filled powdered sample in a disposable glass silicate vial closed with a plastic lid was centrally placed onto the Foss Rapid Content Analyzer sample presentation glass. The scanning of samples at ambient temperature gives NIR spectra within 30 seconds. The major proposed compounds in M. uniflorum were 3,4-dihydroxybenzoic acid, caffeic acid, chlorogenic acid, ferulic acid, gallic acid, kaempferol, linolenic acid, niacin, quercetin, sinapinic acid, syringic acid, and vanillic acid. Whereas coumaric acid, fructose, galactose, L-serine, raffinose, stachyose, sucrose, threonine, and tyrosine were detected in P. lunatus, and the NIR suggested the presence of caffeic acid, ferulic acid, sinapinic acid, phytic acid, leucine, and valine in P. vulgaris. NIRS is an advanced innovative technology extensively used in chemical, food, petrochemical, and pharmaceutical industries for rapid and reliable standardization. The present study revealed an excellent correlation to conclude that flour samples of all three legume seeds could be added to the food system to achieve nutritional and functional benefits.

Dr. salman ahmed

The exploration encompasses the diverse dimensions of the Verbesina genus, a cluster of flowering plants within the Asteraceae family, comprising 340 species with varied growth patterns and floral attributes. Traditional medicinal practices associated with Verbesina species across different cultures are scrutinized, emphasizing the necessity for scientific validation of these ethnomedicinal traditions. Through chemical and pharmacological profiling, Verbesina plants reveal a plethora of bioactive compounds and therapeutic potentials, propelling drug discovery and development opportunities. Safety considerations, conservation challenges, and sustainable harvesting practices emerge as pivotal factors in maximizing the benefits of Verbesina species while minimizing environmental impacts. Finally, we underscore the significance of collaborative research efforts, recognizing the invaluable contributions of our professional colleagues and researchers in related fields in fully harnessing Verbesina plants' medicinal, healthcare and conservation potentials, promising groundbreaking discoveries and applications with profound implications for human well-being.

Dr. salman ahmed

Nanomaterials have been widely used in many fields in the last decades, including electronics, biomedicine, cosmetics, food processing, buildings, and aeronautics. The application of these nanomaterials in the medical field could improve diagnosis, treatment, and prevention techniques. Graphene oxide (GO), an oxidized derivative of graphene, is currently used in biotechnology and medicine for cancer treatment, drug delivery, and cellular imaging. Also, GO is characterized by various physicochemical properties, including nanoscale size, high surface area, and electrical charge. However, the toxic effect of GO on living cells and organs is a limiting factor that limits its use in the medical field. Recently, numerous studies have evaluated the biocompatibility and toxicity of GO in vivo and in vitro. In general, the severity of this nanomaterial’s toxic effects varies according to the administration route, the dose to be administered, the method of GO synthesis, and its physicochemical properties. This review brings together studies on the method of synthesis and structure of GO, characterization techniques, and physicochemical properties. Also, we rely on the toxicity of GO in cellular models and biological systems. Moreover, we mention the general mechanism of its toxicity.

Kamal singh

Telangana, a rapidly developing state in India, is committed to transforming its higher education landscape to meet the demands of the 21st century. This abstract outlines the key strategies and initiatives being implemented to elevate educational standards and ensure that students receive a world-class learning experience. This paper explores the efforts and strategies implemented to elevate the standards of higher education in Telangana, focusing on the challenges and opportunities encountered in delivering quality education. Over the past decade, Telangana has taken significant steps to enhance its higher education system by improving infrastructure, curriculum, teaching methodologies, and fostering collaborations with national and international institutions. The introduction of state-specific initiatives, such as the Telangana Academy for Skill and Knowledge (TASK), along with reforms in university governance, accreditation processes, and the promotion of research and innovation, has played a crucial role in improving educational outcomes. The paper also delves into the socio-economic impact of these improvements, particularly the increased employability of graduates, their contributions to the local economy, and the role of emerging institutions like Young India Skill University. By addressing both the successes and ongoing challenges, this study aims to provide insights into how quality higher education can be a catalyst for regional development and social mobility in Telangana.

Dr gedam kamalakar

Pengembangan budaya keagamaan di sekolah merupakan suatu kewajiban yang harus dilaksanakan oleh sekolah dengan mendesain program pendidikan agama islam yang mengarah pada pengembangan budaya keagamaan. Fokus penelitian ini adalah Bagaimana perencanaan pengembangan program pembelajaran Pendidikan Agama Islam dalam meningkatkan budaya keagamaan di SDN Bletok Bungatan Situbondo? Bagaimana pelaksanaan pengembangan program pembelajaran Pendidikan Agama Islam dalam meningkatkan budaya keagamaan di SDN Bletok Bungatan Situbondo? dan Bagaimana pengawasan pengembangan program pembelajaran Pendidikan Agama Islam dalam meningkatkan budaya keagamaan di SDN Bletok Bungatan Situbondo? Penelitian ini menggunakan pendekatan deskriptif analisis, jenis studi kasus. Teknik pengumpulan data menggunakan wawancara, observasi, dan dokumentasi. Analisis data menggunakan model interaktif dan keabsahan data menggunakan triangulasi sumber. Hasil dari penelitian ini menunjukkan: 1) Perencanaan pengembangan program pembelajaran pendidikan agama islam dalam meningkatkan budaya keagamaan di SDN Bletok Bungatan Situbondo, yaitu: penyusunan buku pintar, Penugasan anggota membuat rancangan kegiatan, nilai-nilai karakter prioritas utama, rencana strategis pendekatan botton up, perencanaan pengembangan budaya keagamaan oleh tim agama. 2) Pelaksanaan pengembangan program pembelajaran pendidikan agama islam dalam meningkatkan budaya keagamaan di SDN Bletok Bungatan Situbondo, yaitu: Roling tanggung jawab job deskription pengembangan budaya, Quality Insurence (Jaminan Mutu) pembiasaan keagamaan, Model uswah guru, pelaksanaan Budaya keagamaan. 3) Pengawasan pengembangan program pembelajaran pendidikan agama islam dalam meningkatkan budaya keagamaan di SDN Bletok Bungatan Situbondo, yaitu: pengawasan internal kinerja anggota dan eksternal melalui pengguna layanan siswa dan orang tua, evaluasi supervisor sekolah terhadap kinerja anggota, anak berkepribadian sesuai dengan nilai-nilai agama, monitoring oleh komponen sekolah dan tim agama, monitoring siswa, monitoring tingkah laku dan pembiasaan siswa, penetapan capaian dari Quality Insurence.

Educare: journal of primary education

Background: Prescribing patterns in systemic hypertension vary from place to place. Studies have shown that cost could be one of the factors responsible for non-adherence to treatment among hypertensive patients. Nigerian pharmacoeconomics studies have not provided a general guide on cost-effective prescribing for hypertensive patients in the country. The aim of the study was to examine the prescribing patterns, do cost effectiveness and cost minimisation analyses of the commonly prescribed antihypertensives, and determine if cost is a major reason many of the hypertensive patients of the District Hospital are usually lost to follow up. Methods: 5267 adult (≥18 years) non-antenatal patients’ cards of 2016 were reviewed for hypertension. Examination of the prescriptions, cost-effectiveness and cost-minimisation analyses of the commonly prescribed antihypertensives were done. Results: 12.6% of the patients were hypertensive. 73% of these hypertensive patients were treated pharmacologically. 40.8% adhered to treatment. 73% of the adherent ones responded to treatment. Amlodipine was the most expensive prescribed antihypertensive (N22). Amiloride-hydrochlorothiazide with the largest cost effectiveness ratio (CER) (9) was the most cost effective of all the combinations. Lisinopril- hydrochlorothiazide (N17) was preferable to the triple combination of lisinopril-amlodipine-hydrochlorothiazide (N39), and amlodipine-hydrochlorothiazide (N32) in cost minimisation. Conclusions: Cost of drugs probably had played a significant role in non-adherence to treatment among hypertensive patients in the District Hospital in 2016, since moduretic with the largest CER (9) and nifedipine with the greatest BP reduction when combined with hydrochlorothiazide (56/22 mm Hg) were rarely prescribed.

Emmanuel umegbolu

s deep learning models continue to grow in complexity, the computational and energy demands associated with their training and deployment are becomingincreasingly significant, particularly for convolutional neural networks (CNNs) deployed on CPU-bound and resource- limited devices. Fully connected (FC)layers, while vital, are energy-intensive, accounting for 85.7% of a network’s parameters but contributing only 1% of the computations. This research proposes anovel approach to optimising these layers for greater energy efficiency by integrating low-rank factorisation with differential partial differential equations (PDEs).The introduction of the LowRankDense layer, which combines low-rank matrix factorisation with a differential PDE solver, aims to reduce both the parametercount and energy consumption of FC layers. Experiments conducted on the MNIST, Fashion MNIST, and CIFAR-10 datasets demonstrate the effectiveness ofthis approach, yielding promising results in terms of reduced energy usage and maintaining comparable performance, thereby enhancing the practicality andsustainability of CNNs for widespread use in environments with limited computational resources

Jiby mariya jose

The potential of endemic medicinal plants in Yemen for sustainable pharmaceutical applications is home to a diverse and unique flora, with a significant proportion of endemic and near-endemic species that are traditionally used in folk medicine. This study documents 16 medicinal plant species from Abyan Governorate, Southeastern Yemen, and analyzes their traditional therapeutic uses and the extent to which they have been phytochemically investigated. The majority of these species are used to treat skin diseases, wounds, and burns. However, the findings indicate that 56.3% of these plants have not yet been studied for their active compounds. The Asclepiadaceae family was the most represented among the studied taxa, yet remains largely chemically unexplored. The study emphasizes the importance of preserving ethnobotanical knowledge and recommends future phytochemical screening and pharmacological validation of under-researched species for sustainable use in pharmaceutical development.

Mediterranean journal of pharmacy and pharmaceutical sciences

This study aims to assess tourists‟ perceptions towards quality tourism services provided at Petra historical site, and to measure tourist satisfaction by examining the impact of quality tourism product on overall tourist satisfaction. In this study, four hypotheses were developed are proposed a study model. The empirical data were collected from tourists via a survey that yielded 180 usable questionnaires, these data were analysed using a series of multiple regressions to determine the relationship between service quality and tourist satisfaction. The findings confirmed that service quality directly impacted tourist satisfaction throughout destination facilities, destination accessibility and destination attraction. As a result, this study argued that there is a significant impact of the service quality on tourist satisfaction, and therefore service quality plays an important role in tourism by increasing the level of tourist satisfaction. The results in this study supported the evidence that there are positive impacts of components of tourism product on tourist satisfaction. This study provided some theoretical and managerial implications based on the findings to academicians and tourism sector, the researcher presented recommendations for further studies and he discussed the main limitations in this study

Mukhles m. al-ababneh

A simple one pot synthesis has been developed for the synthesis 1,4-dihydropyridine using an efficient and reusable silica supported MgO solid catalyst by condensation of dimedone, ethyl acetoacetate, aldehyde and ammonium acetate in methanol as a solvent at room temperature. The reactions could be carried out under mild reaction conditions with very good yield of polyhydroquinoline, up to 92%. This catalyst could be recycled very easily, which makes this methodology environmentally benign.

Shilpa sangle

This paper centers around how innovations adds to enhancing interoperability between IoT gadgets, and making effectively utilization of IoT gadgets. The proposed stage innovation gives semantic-based IoT data administrations, and semantic interoperability of IoT gadgets. This administration stage can be material to a great deal of semantic IoT administrations: gathering imperceptible data in genuine condition by brilliant gadgets, giving keen life benefits by sharing, taking an interest, circulating open detecting data.

Dr h shaheen

Background: Hyoscine N-butylbromide (HBB; Buscopan) is commonly used in obstetric practice to accelerate labor and facilitate cervical dilation, yet variability in knowledge, attitude, and clinical usage persists among practitioners. This study assessed the knowledge, attitude, and usage patterns of HBB among medical practitioners at Abia State University Teaching Hospital (ABSUTH), Aba, Nigeria. Methods: A descriptive cross-sectional survey was conducted between August 2024 and April 2025 among 102 medical practitioners directly involved in labor care at ABSUTH. A structured, self-administered questionnaire, validated through expert review and pilot testing (Cronbach’s α = 0.78), was used to collect data on demographics, knowledge, attitude, and usage patterns. Descriptive and inferential statistics, including Chi-square tests and Pearson correlations, were performed using SPSS v. 25.0. Significance was set at p < 0.05. Results: Among 102 respondents, 93.1% had heard of HBB, and 70.6% correctly identified it as an antispasmodic. While 69.6% recognized its primary mechanism as cervical relaxation, 48% were aware of contraindications. The majority agreed that it is effective (mean = 4.12) and improves maternal outcomes (mean = 4.01). About 85.3% had administered it during labor, mostly in the active phase (64.7%), with the intravenous route being most preferred (56.9%). Statistically significant associations were observed between knowledge and attitude (χ² = 18.442, p = 0.001), specialty and frequency of use (χ² = 12.695, p = 0.048), and formal training with dosage knowledge (χ² = 15.210, p = 0.002). Knowledge, attitude, and usage scores were significantly correlated (p < 0.01). Conclusions: While the majority of practitioners at ABSUTH are familiar with and frequently use HBB in labor management, knowledge gaps and variations in practice remain. Strengthening formal training and incorporating standardized protocols could improve evidence-based usage and maternal outcomes.

Karishma

Malwares are one of the most dangerous security threats in today’s world of fast growing technology. Now, it is not impossible to remotely lock down a system’s files for ransoms even when it is located overseas. This threat was accelerated when the world was introduced to cryptocurrency (for e.g., Bitcoins). It allowed the attackers to hide their tracks more efficiently. From a simple idea of testing the efficiency of a computer system to the most critical and sophisticated cyber-attack, malwares has evolved over the years and appeared time to time. Even with the smartest technologies today where we are trying to include Machine learning and Deep learning to every field of our life, the attackers are already developing more sophisticated malwares using the same Machine learning and Deep learning techniques. This raises the question on the security of the cyber-world and how we are able to protect it. In this work, we are presenting an analysis on a recent and most critical Windows malware called “LockerGoga”. Both static and dynamic analyses are performed on the malware to understand the behavior and characteristics of the malware.

Dr. chandrashekhar uppin

Plants, the beauty of nature, have been the basis For treating human ailments. The current accepted modern medicine has gradually developed over the years and is undoubtedly the gift of God in the sense of traditional knowledge about different medicinal plants. However, what is needed are rapid screening techniques, structure base design and combinatorial chemistry for drug development under innovations, which will share the profit of products derived from indigenous plants. There is less known information about Ficus exasperata Vahl., and Cleome ciliata Schmach and Thonn. However, the author of this book presents comprehensive information about traditional uses and the biological and phytochemical investigation of Ficus exasperata Vahl. and Cleome ciliata Schmach and Thonn.

Dr. salman ahmed

Supply chain management, especially in manufacturing companies, is very important as the companies rely on the raw materials needed for production. Moreover, the success of a company is also determined by how it could gain competitive advantage to compete in the industry. It is proven that a company with effective supply chain management and competitive advantage would perform better. The purpose of this research is to see the effect of supply chain management and competitive advantage on company performance conducted at PT Ahlindo Perkasa Alam. This research uses quantitative method with Census sampling of 32 employees working in the company. The test results show that Supply Chain Management and Competitive Advantage have a positive significant effect on Company Performance at PT Ahlindo Perkasa Alam as much as 76.1%.

L

Community pharmacist plays an essential role in educating the epileptic patients about their disease and medications. Improving the patient’s awareness may lead to improve their compliance and decrease drug-drug interaction and ultimately improve their quality of life. Pharmacist can detect the emergence of health problems and can help prevent progression of comorbidities. Considering the complexity of treating epilepsy and the lack of information about pharmacists’ contributions to epilepsy management, pharmacist performed pharmaceutical counselling, pharmaco-therapeutic follow-up and systematic measurement and evaluation of findings and increase medication adherence of patient with epilepsy. This study was aimed to assess the community pharmacist's knowledge about epilepsy and their treatment by antiepileptic drugs in Libya. The design of the study is a cross sectional study. The knowledge was collected through a questionnaire which included 35 questions divided into three sections: demographic data, general information about epilepsy and information about epilepsy and antiepileptic drugs. The questionnaire was prepared and validated by consultant training in Ali Omer Asker Hospital in Tripoli for two months. The findings indicate that over 200 patients are altered viewed, of whom, only epileptic patients were observed. The majority of the participants were female, qualification degree BSc and years of experience from one to five years. Unfortunately, some of the participants (40.0%) had poor knowledge and about 60.0% of them had good knowledge. This study indicates that the importance of community pharmacist in Libya requires more improvement to achieve the existing function and that the impact of continuous study of everything related to diseases and medicines is important to obtain a qualified pharmacist who can become an effective agent for a change.

Mediterranean journal of pharmacy and pharmaceutical sciences

If you already have a research project in mind, the research planning phase must be completed with the formulation of a wellstructured research proposal that must be submitted to an ethics committee for approval before your project can start. Generally, a research proposal contains the following elements: Title, abstract, introduction, objectives, methodology, timeline and milestones, ethical considerations, budget, appendices, and references. Whether you are a medical student or a researcher, knowing how to write a research proposal is an important skill to start any research project. This guide will give you the skills to write a successful research proposal.

Karishma

Financial literacy education is a lifelong asset that every individual needs to function and fit well in modern-day society. It provides the financially savvy better decision making, best investment alternatives and family wellbeing. Unfortunately, most consumers especially in this part of our world appear relatively less active and less confident in participating meaningfully in the financial sector due to a lack of knowledge about the complex nature of financial products and services and indeed the risk that goes with them. As a contribution in addressing this problem, this study looked at financial literacy education and its implication on the economic and social life of the teacher in the Upper East Region of Ghana. With a descriptive survey design, 118 participants responded to questionnaires. Results showed low levels of financial literacy among participants which can negatively affect their daily financial management. It is therefore definite that the financially literate has the advantage to undertake prudent alternative investment decisions and is able to make informed retirement planning. Being financially illiterate adversely affects one’s life in relation to the culture of savings, expenditure pattern, investment decisions and budgeting skills, making the individual economically insecure. The study has policy frontier implications; policymakers in the financial sector, governments, non-governmental organisations and equity owners are encouraged to come to the aid of consumers, especially teachers, by way of introducing professional teacher development programmes specifically tailored at uplifting their financial literacy knowledge and skills.

Juabin matey

The current study used the chick emesis model to explore the anti-emetic effect of the methanolic extract of Acalypha ornata Hochst—roots. Emesis was induced by the oral administration of copper sulfate to male chicks. Acalypha ornata root extract (150 mg/kg orally) showed an anti-emetic effect and was compared with the reference drug chlorpromazine

Dr. salman ahmed

Internet of Things (IoT) enhances the global connectivity to all the remote sensing devices. It enables the connectivity of communication and processing the real-time data that has been collected from an enormous number of connected sensing devices. There is an increase in the IoT technology that leads to various malicious attacks. It is more important to overcome the malicious attacks, mainly to stop attackers or intruders from taking all the control of devices. Ensuring the safety and accuracy of the sensing devices is a serious task. It is very much important to enabling the authenticity and integrity to obtain the safety of the devices. Dynamic tree chaining, Geometric star chaining and Onion encryption are the three solutions that has been proposed in this project for in order to enable authenticity and integrity with information hiding for secure communication. The simulation results are driven displays that the proposed system is very stable and much better than other existing solution in means of security, space and time.

Jebin bose s