This study aims to determine the process of implementing PJOK learning in limited face-to-face learning during the Covid-19 pandemic in class V MIN 2 Palangka Raya City. This type of research is qualitative with case studies. Data collection techniques by observation and interviews. Meanwhile, data analysis uses descriptive data analysis. The results of this study show that:1) planning for sports and health physical education learning during the Covid-19 pandemic in MIN 2 Palangka Raya City: Teachers plan the PJOK class V learning program, develop the Annual Program, carry out Semester Program activities, carry out learning plans in the learning syllabus, distribute effective weeks.2) Implementation of Sports and Health Physical Education learning in MIN 2 Palangka Raya City, namely: development of the Annual Program into the Learning Implementation Plan, carrying out Semester Program activities, implementation of learning plans in the learning syllabus, online teaching, and learning process activities teachers explain teaching materials, apply learning methods.
Background: Although geriatric depression is widespread in primary health care (PHC), local studies on the prevalence of depression in elderly PHC patients appear to be scarce. This study aimed to determine the prevalence of depressive symptoms and some of the associated risk factors among elderly PHC patients. Methods: A cross-sectional study recruiting elderly people (60 years or older) from five PHC centers in Port Said Governorate was conducted. All participants had a structured interview. The long version of the geriatric depression Scale (cut-off point ≥10) was used in elders with a Mini-Mental State Examination ≥24. Results: About two-thirds of the total sample (65.7%) was female. The total prevalence of depressive symptoms was 49.4% of all subjects, more commonly in women (58.1% vs. 32.8%). Multiple regression analysis shows that female gender, high education, unemployment, low income, lonely life, loss of a close person, chronic diseases, tumor, iatrogenic medications, and depression history were the significant associated risk factors of depression in the studied elders after adjusting all previous variables in addition to age and marital status. Conclusion: Depressive symptoms constitute a significant health problem among older PHC patients in the Port Said governorate. Routine screening for depression of every elderly PHC patient is recommended for early detection.
Intensively cultivated rice-wheat cropping system of the Indo Gangetic plain (IGP) is a potential source of greenhouse gas (GHG) emissions.Agriculture sector emits GHGs like methane (CH4) and nitrous oxide (N2O). The total amount of GHGs emitted by a product is known as its carbon footprint (CFP).Quantification of CFP of crops will help in identifying management practices to reduce CFP of crop production. Studies related to assessing of CFP of agricultural products are lacking. The present review paper was aimed to discuss about the studies done on GHG emission from rice-wheat cropping system of the Indo Gangetic plains. The paper elaborates on what is CFP, how to calculate CFP of rice-wheat cropping system with the help of different case studies. The paper provides insights about certain agricultural management practices which can help in reducing CFP of rice-wheat cropping system. Discussion from this paper signifies the importance of carbon footprint assessment in maintaining the sustainability of rice wheat cropping system.
Ascorbic acid (vitamin C) is a water-soluble vitamin; it is present in the highest concentration in the brain. Ascorbic acid in high doses acts as a potential treatment for various neuropathological and psychiatric conditions. Flumazenil is a benzodiazepine antagonist; it competitively inhibits the activity of benzodiazepine and non-benzodiazepine substances that interact with benzodiazepine receptors site on the GABA/benzodiazepine receptor complex. This study aims to investigate the effect of flumazenil on the anxiolytic action of ascorbic acid using an elevated plus maze model of anxiety in rats. Male Albino Wistar rats weighing between 250 and 320 grams were used. Rats were divided into four equal groups of seven rats each and treated as follows: Group I, the control group received a single dose of 1.0% tween 80; Group II treated with a single dose of 125 mg/kg ascorbic acid; Group III was injected by a single dose of 1.0 mg/kg flumazenil; Group IV received a combination treatment of 125 mg/kg ascorbic acid and 1.0 mg/kg flumazenil. Behavioural measurements using a plus maze were scored 30 min after the administration. The parameters scored are the time spent on the open and closed arms, the lines and number of entries into open and closed arms, and the anxiety measure. Ascorbic acid decreased anxiety measure and increased the total lines and total number of entries; this effect was abolished by the administration of flumazenil with ascorbic acid. Thus, ascorbic acid produces an anxiolytic-like effect in rats; this effect was abolished by flumazenil administration with ascorbic acid. This may indicate that the GABA/benzodiazepine receptor complex has to be stimulated to produce the anxiolytic effect.
Mediterranean journal of pharmacy and pharmaceutical sciences
The planned opening of foreign universities will foster cultural exchange, expose Indian students to diverse perspectives and promote international understanding, according to Gedam Kamalakar. Foreign university campuses have the potential to attract foreign investment, create job opportunities and stimulate the local economy through increased spending on infrastructure, accommodation and services. Partnerships with foreign universities on joint research projects will enhance knowledge exchange and technological advancements. Nevertheless, the influx of foreign universities can pose a threat to domestic educational institutions by alienating talented students and faculty and exacerbating inequalities in access to quality education. There is hence a danger of cultural imperialism. Indigenous knowledge and traditions may be marginalised due to the dominance of Western educational systems and values. Increasing opportunities to study abroad may also increase brain drain.
In this report, Abacus Ltd employee will offer his client guidelines, another organisation trying to comprehend risk management. Abacus gives a scope of business consultancy administrations to their clients which assist them with developing their business. Abacus's new client wants all individuals from the senior group to comprehend risk management in business and the various kinds of danger (Aven and Renn, 2010).
This chapter discusses the effects of stimuli that combine sexuality and aggression. It outlines the debate over aggressive versus nonaggressive pornography and discusses the frequency of aggressive pornography and bases for concern. Aggressive pornography and sexual arousal is explored in the chapter wherein initial findings, victim's responses, individual differences, context of assessment, and conclusions are discussed. The chapter reviews the effects of aggressive pornography on responses other than aggression wherein it has discussed about changes in sexual responsiveness, fantasies, and perceptions and attitudes. The effects of aggressive pornography on aggression are explored in the chapter wherein research findings are discussed in detail and summary of effects on aggression, theoretical analyses, and the construct validity of assessing aggression are also described. The data across the laboratory and field experiments discussed in this chapter raise a variety of theoretical and empirical issues that should be addressed in future research. Particularly noteworthy are questions concerning stimuli, subject, and setting characteristics.
Vigna aconitifolia (Jacq.) Marechal. (Papilionaceae) is a medicinally important plant used for treating different diseases, especially dermatological disorders. Alkaloids, phenols, flavonoids, and phytic acid have been reported in this plant. Vigna aconitifolia also exhibits antioxidant, antidiabetic, and hypocholesterolemic activities. The present review attempts to compile all the previous data based on its medicinal uses, phytochemistry and pharmacology reported in the earlier articles.
La socialisation en Afrique de l’Ouest se fait par des canaux normatifs dont le mariage. Ce lien sacré, scellé par les Hommes et béni par Dieu, est une nécessité humaine et reste un goulot social pour plusieurs femmes. Sur cette entité géographique patriarcale, la condition féminine relève très souvent d’’un chemin de croix’ pour un épanouissement multiforme. Issoufi DICKO et Safiatou BA se saisissent de cette facette de la thématique du genre pour questionner les vies et les règles traditionnelles en contexte de modernité. Les deux jeunes écrivains maliens portent, entre condition féminine et inversion sexuelle, un regard sans complaisance sur leur société en profonde mutation. Trame nourricière de leurs ouvrages respectifs, ces thèmes leur permettent de mettre en scène des personnages hauts en couleur et en courage. Contrariées en partie par leurs quotidiens et la vie, le système patriarcal et l’embrigadement socioreligieux, leurs héroïnes s’indignent et se révoltent contre les sorts qui leur sont imposés. Défiant les règles de la vie en couple et celles socio-culturelles, elles s’érigent en rempart des dérives sociales perpétrées contre les femmes. Parallèlement à la condition féminine et les conflictualités de la vie en couple, le lesbianisme balbutiant au Mali est convoqué. Issoufi DICKO et Safiatou BA décrivent méticuleusement les arcanes de son enracinement progressif. Cette contribution aborde, avec la méthode qualitative, la condition féminine et l’homosexualité au Mali, entre fiction et réalité sociale. L’objectif de cette contribution est d’analyser la condition féminine et l’homosexualité à travers les deux romans.
The problem of chemical fertilizers and pesticides can be solved by the action of plant growth promoting fungi (PGPF). The indigenous fungal isolates obtained from the rhizosphere soil can be used as they are said to solubilize the insoluble zinc, phosphorous, potassium etc. They are known to control the different fungal pathogens and thus promoting the plant growth and health. In the present study, attempt was made to isolate soil beneficial fungi from the rhizosphere soil samples of important medicinal plants such as Aegle marmelos, Azardirachta indica and Citrus limon. A total of 22 fungal isolates was isolated and screened for their efficacy on phosphate and zinc solubilization and antagonistic potential against selected plant pathogenic fungi under in vitro condition and the isolates were identified up to species level.
Using realia media in learning activities will provide an interesting learning experience for students so that they are more active in participating in learning. This discussion aims to describe and analyze the application of realia media in improving student learning outcomes at MIMA 35 Nurul Ulum Jember. The research approach uses qualitative and case study research types. Data collection techniques using observation, interviews, and documentation. Analysis of the data used in this study using the Miles and Huberman model consisting of data condensation, data presentation, and concluding. The validity of the data was tested by using triangulation of sources and techniques. The results of this study indicate (1) Realia media planning in improving student learning outcomes at MIMA 35 Nurul Ulum Jember, namely: Identifying the needs and characteristics of students, formulating learning objectives, summarizing material, writing instructional media scripts, conducting tests and revisions. (2) The implementation of realia media in improving student learning outcomes at MIMA 35 Nurul Ulum Jember, namely: the teacher learns the instructions for using the media, and all equipment must be in a state of readiness so as not to be disturbed by technical matters, and keep students steady. conducive for learning activities to take place. (3) Evaluation of realia media in improving student learning outcomes at MIMA 35 Nurul Ulum Jember, namely: learning media according to KD and indicators, learning media according to the estimated time and assignments in the Buena book, learning media can attract students' attention, media learning is in accordance with the times/updated, thematic assessment criteria are spiritual, social, knowledge, and skillful.
The study, “The beginnings of the organization of the Kosovo Liberation Army in the Lap Operational Subzone December 1995 – June 1998,” as its object of study has the period of the Kosovo Liberation War in the years 1998-1999. This study touches upon the historical dimension of the efforts and sacrifices of Albanians found in the Serbian-Yugoslav area against their will.This study’s main topic is the beginnings of the organization in the Lap Operational Subzone (LOSz) as a significant part of the KLA. The study has undergone a scientific analysis based on sources of all kinds. The analysis included LOSz’s position in the KLA structure: the mission and duties during the liberation war, the governing bodies at the beginning of the LOSz organization and their functional organization, as well as the battles and downfalls of the freedom fighters. Historical literature, feuilletons, scientific papers, as well as interviews with famous personalities, were used to shed more light on the organization and the war in LOSz. This topic covers an essential segment of the Kosovo Liberation War period 1998-1999 And contributes towards the complete enlightenment of this historical period, especially in this region. Therefore, hopefully, this study will build interest and create perspectives for new studies of this nature.
Natural products the most significant source for pharmaceutical development have been investigated and utilized to alleviate diseases since early human history. Natural compounds from both terrestrial and marine organisms have been extensively used for the treatment of many diseases either in their natural form or as a template for synthetic modification. A variety of new chemical entities from natural resources at present are undergoing clinical trials. The government sector, industries and academic institutions also play an important role in the natural drug development for human health enhancement.
Chronic kidney disease is a public health problem affecting people worldwide. This study was aimed to examine the characteristics of patients with chronic kidney disease and to identify prevalence of drug-related problems among Libyan patients. This is a descriptive retrospective study carried out in Southern-west part of Libya, Sebha City. Information abstraction forms were used for collection of data. The investigators reviewed the medications, medical records and laboratory data to identify drug-related problems.1 000 patients' files during 2019-2020 were examined and only 120 files were selected for this study. The majority of the participants were male (73, 61.0%) and the mean age was 56.1 years. 576 comorbidities among the selected patients were identified (73.61%) and the average number per patients was 4.8 concurrent diseases. There were 1 350 medications prescribed and the average of prescribed drugs per patient was 11.25. The majority of patients use more than 10 drugs (64, 53.3%) and the average length of staying in the hospital was 5.58 days. 502 drug-related problems were identified with an average of 4.18 per patient. Untreated conditions such as Hyponatremia and anemia were the highest rate of drug-related problems identified (199, 39.6%) followed by improper drug selection (82, 16.3%) such as cefotaxime, vancomycin and aminoglycoside for chronic kidney disease and drug use without indications such as antibiotics (68, 13.5%) and over-therapeutic dose such as metoclopramide(63, 12.5%). In conclusion, all the patients have polypharmacy and the majority have comorbid conditions and chronic kidney disease with frequent drug-related problems, thus, to lower the incidence rate of drug-related problems, therapeutic interventions are needed. Subsequently, it is a crucial to involve clinical pharmacist in hospital to improve the care of patient with chronic kidney disease.
Mediterranean journal of pharmacy and pharmaceutical sciences
Breast cancer is the most prevalent invasive form of cancer in females and poses a significant challenge to overcoming the disease burden. The growth in global cancer deaths mandates the discovery of new efficacious natural anti-tumor treatments. In this regard, aquatic species offer a rich supply of possible drugs. Studies have shown that several marine peptides damage cancer cells by a broad range of pathways, including apoptosis, microtubule balance disturbances, and suppression of angiogenesis. Many side effects, including immune response suppression, characterise traditional chemotherapeutic agents. The discovery of novel putative anti-cancer peptides with lesser toxicity is therefore necessary and timely, especially those able to thwart multi-drug resistance (MDR). This review addresses marine anti-cancer peptides for the treatment of breast cancer.
Ageing is an inevitable phenomenon. Similar to other organs, skin is also subject to an intrinsic ageing process. Additionally, skin ageing is also influenced by various environmental factors. Existing conventional formulations have limited efficacy because skin serves as a rate limiting barrier for percutaneous absorption of drugs. This has led to the evolution of various novel drug delivery systems. Among these liposomes have received considerable attention due to the numerous advantages they offer. Liposomes, submicroscopic spherical vesicles, were discovered in 1960’s. Since then, they have gained popularity as potential carriers for drugs, diagnostics, nutrients, vaccines and other bioactive agents. Liposomes find applications in pharmaceutical, cosmetics and other industrial fields. Various topical actives that have been found to be efficacious in delaying the signs of ageing have been formulated as liposomes resulting in enhanced delivery, biocompatibility, and reduced toxicity. This review focusses on therapeutic use of liposomes in skin ageing.
Effective crisis communication response through using the proper strategies is critical to cope with crises and to protect the reputation and existence of the involved parties. Usually, aviation accidents receive great attention from the media and the public. Malaysia Airlines Flight 17 (MH17) which was shot down over eastern Ukraine on 17 July 2014 during its scheduled flight from Amsterdam to Kuala Lumpur received global attention. This attention was due to the involvement of several countries either at the level of the countries of victims or the countries accused of the attack. Image repair theory proposed by William Benoit, the widely used in crisis communication response was implemented in this study. The Russian response to the international accusation, especially from the Western world on supporting the attackers of MH17 has been examined in this study. This study implemented both quantitative and qualitative content analysis to achieve its aims. A total of 306 news stories from the online New Straits Times newspaper Website from the years 2014 to 2019 were analysed. A total of 191 strategies were included in 123 news stories since some stories combined more than a strategy. Out of 191 strategies, 43.5% were simple denial, followed by shift the blame and attack accuser with 35.1% and 21.5% respectively. The results revealed that the image repair effort by Russia was effective and successful.
Social competence is often seen as a desirable trait during adolescence as it is considered as a protective factor in resilient individuals. It promotes personal and interpersonal effectiveness by enhancing skills needed for dealing with environmental challenges in daily life situations. Poor social competence has been associated with a number of psychosocial troubles during adolescence, including mental disorders, emotional and behavioral problems. Of the many skill building programs used to enhance adolescent social competence, Life Skills Education and Training have been significant ones. The present study investigates the utility of life skills training in enhancing social competency during adolescence. A pre- and post-test experimental design was used in the study to analyze the stated objectives. Adolescent Social Competency Scale was used to select the study sample. 160 adolescent students (mean age=16.44) who scored low on social competence participated in the study. These were randomly divided into the experimental and control group (n=80), consisting of equal number of male and female adolescents (n=40). Participants in the experimental group were trained on six of the ten core life skills, based on the module prepared by the researcher. The training lasted for 10 sessions following which post-test assessments were done. Data obtained was analyzed using descriptive statistics like mean, standard deviation and inferential statistics including independent sample t-test and repeated measures of ANOVA. The results of the study indicate a significant effect of life skills training in enhancing adolescent social competence, irrespective of gender.
Strain improvement studies were conducted for the production of L-asparaginase from a marine fungus Beauveriabassiana SS18/14 by employing physical and chemical mutagens, in a systemic manner to obtain mutants that have higher L-asparaginase production. The wild strain produced 6.32 IU/mL of L-asparaginase activity while the UV mutant UVF-4 yielded 8.34 IU/mL and nitrous acid mutant UVF4-N-2 exhibited 10.44 IU/mL enzyme activity. The overall strain improvement programme increased L-asparaginase activity 1.65 times with respect to the parent wild strain.
Network on a chip is a concept in which a single silicon chip is used to implement the com-munication features of large-scale to very large-scale integration systems. For high-end System on Chip de-signs, Network on Chip is considered the best integrated solution. NoC has several advantages over dedicat-ed wiring and buses i.e. increased bandwidth, low latency, less power consumption and scalability. Reduc-tion in the latency (end-to-end latency and network latency), loss probability, energy consumption and re-sponse time are the basic parameters which are considered by the researchers for the optimization of the networks-on-chip topologies. In this paper we review the most popular technologies and also some recent topologies for interconnection networks. We study their performance and summarize their strengths & weakness.