This study conducted a simulation-based time-domain short-circuits fault evaluation and protection system reliability analysis in 300 MVA substations with 132 kV transmission lines in Asaba (Ibusa/Asaba), Delta State, Nigeria. The analysis focused on two primary parameters: protection system dependability and selectivity, to determine the conditions necessary for ensuring rapid fault clearance and stable substation operation under line-to-ground, double-line, and three-phase faults. Fault currents, voltages, and relay trip signals were generated and analyzed using MATLAB time-domain simulations. Results indicated that system dependability exceeded 97% and security surpassed 95% when total fault-clearing times remained below 120 ms. Relay coordination intervals of 0.2–0.4s, backup misoperation below 3%, and circuit breaker MTBF above 20,000 h ensured selective fault isolation. Extended fault durations beyond 120ms or improperly coordinated relay settings increased the likelihood of misoperation and voltage instability. It was concluded that uninterrupted substation operation depends on integrating time-domain fault evaluation, coordinated relay settings, and reliable breaker performance into protection management protocols. Accordingly, it was recommended that substation operators maintain precise relay coordination, implement continuous time-domain monitoring, and uphold breaker maintenance schedules. These actions will further enhance the protection reliability, reduce fault propagation risks and support safer, more stable operation of the 132 kV transmission network.
Personnel Department is the predominant component of HRD unit of North Eastern Karnataka Road Transport Corporation (NEKRTC), though HRD has been identified and designated as a separate Department. Basically the existing Personnel Department is qualified to be called HR Department OR even a better name would be Human Resources Management Department, since it would correctly reflect the comprehensive and all inclusive nature of the functions of the existing Personnel Department, which covers all features of Human Resources Management, namely Forecast of requirement of Human Resources, Planning for Recruitment, In-service care Co-ordination, Control and Regulation as also Retirement and all matters related to Personnel Administration. It should be its function to plan for training appropriately along with recruitment of personnel from all the Departments. The present Human Resource Development. Is ill-equipped and does not have the comprehension of concept and perception of HRD.
Pharmacy education has evolved from the outdated changing 5 to 4 year dispensing pharmacy program that focus on the medicines value the compounding and dispensing to patient-oriented pharmacy program (Pharm D) that focus on patient, experiential learning (practicum courses), evidence -based program that does foster critical thinking, and clinical reasoning skills [1] and improving patient care.
Mediterranean journal of pharmacy and pharmaceutical sciences
The study of molluscan animals is called Malacology and the study of molluscan shell is called as conchology. The scaling of metabolic rates with body mass is one of the best known and most studied characteristics of aquatic animals. We studied here how body size is related to rate of oxygen consumption, ammonia excretion and O: N ratio in Freshwater Bivalve Mollusc Lamellidens marginalis species in an attempt to know how body size specific changes affect their metabolism. The freshwater bivalve molluscs with specific body size i.e. small (76-79 mm in shell-length) and large (90-94 mm in shell-length) were chosen for experimental work from Bhima River at Siddhatek on April and May during summer. The adult bivalve molluscs with small body size reported high value in rate of oxygen consumption and O: N ratio but rate of ammonia excretion was low value in small body sized bivalves compared to large ones. The results are discussed in the flush of metabolic processes in fresh-water bivalve molluscs.
In this article, we study an Inventory Routing Problem with deterministic customer demand in a two-tier supply chain. The supply chain network consists of a supplier using a single vehicle with a given capacity to deliver a single product type to multiple customers. We are interested in population-based algorithms to solve our problem. A Memetic Algorithm (MA) is developed based on the Genetic Algorithm (GA) and Variable Neighborhood Search methods. The proposed meta-heuristics are tested on small and large reference benchmarks. The results of the MA are compared to those of the classical GA and to the optimal solutions in the literature. The comparison shows the efficiency of using MA and its ability to generate high quality solutions in a reasonable computation time.
The market for tertiary educational institutions, most especially for private universities, is highly competitive. The competitive nature of the market requires that Private Universities (PUs) step up their performance so as to remain competitive despite the major structural and market differences between them and public universities in the provision of tertiary education. The need for private universities to remain competitive in this turbulent market, calls for some careful examination of the factors that would enable private universities to enhance their performance. In this respect, this study sought to examine the effects of management competence, firm-level institutions, and human resource management (HRM) bundles on the performance of private universities in Ghana. Underpinned by the RBV and AMO theories, the study tested four hypotheses that sought to explain the relationships between the key variables of the study. The study was implemented using a quantitative research design. Out of the sixteen private universities sampled, thirteen private universities responded. The main research instrument was a structured questionnaire. Out of 230 questionnaires administered, 127 completed questionnaires were received and used for analysis. Collected data was analyzed using descriptive and inferential statistics (regression analysis) with the aid of SPSS software version 20 and AMOS version 23. Research findings from the tests of hypotheses established that management competence positively and significantly affected performance of private universities in Ghana. Though the study found that the composite variables of firm-level institutions and HRM bundles did not moderate the relationship between management competence and PU performance, the skills bundles (which is a component of the HRM bundles) significantly moderated the management competence – PU performance relationship in such a way that at high levels of skills bundle, management competence influences PU performance more than at low levels of skills bundle. Based on the findings of the study, it is recommended that PUs in Ghana institute competence acquisition and utilization policies, maintain appropriate firm-level institutions and HRM bundles and match these to their competence development strategies.
Periwinkle or Vinca rosea L. has medicinal importance with three phenotypes i.e., Pink, Red eye and White. The present investigation distinguishes the three traits i.e., white, pink and red-eyed flower-bearing traits of V. rosea based on morphology, palynology, pollen grain germination and study of anatomical features of leaf, stem and variations in parts of the flower. The results revealed that significant differences were recorded in stomatal frequency, stomatal index, size of the petals, pollen viability and pollen germination. The highest per cent viability appears in pink flower-bearing plants (98.8%) followed by red-eyed flower-bearing plants (34.3%) and White flower-bearing plants (34%). Similarly, the percentage germination of pollen grains is high in pink flower-bearing plants (98.1%) followed by red-eyed flower-bearing plants (33.3%) and white flower-bearing plants (33.3%).
The primary objective of this study is to conduct a comprehensive analysis of the relationships between liquid- ity (LIQ), capital structure (LEV), and fnancial performance (FIP). Additionally, we seek to investigate the indirect efect of liquidity (LIQ) on fnancial performance (FIP) by examining the intermediary role of the capital structure (LEV) of non-fnancial-listed companies in the Vietnamese stock market. This study utilizes PLS-SEM with a robust sample of 644 non-fnancial-listed companies in the Vietnamese stock market. The fndings suggest that liquidity positively infuences fnancial performance but negatively impacts capital structure. Conversely, capital structure negatively afects fnancial performance. Thus, liquidity indirectly enhances fnancial performance through capital structure mediation. This research result can provide suggestions for non-fnancial enterprises in making fnancial decisions to increase fnancial efciency by increasing the holdings of highly liquid assets to prevent risks and take advantage of new investment opportunities in the future. In addition, increasing the holding of highly liquid assets also reduces debt pressure and reduces interest costs, thereby increasing fnancial efciency. Our research shows that the relationship between economic factors is extremely complex; specifcally, our research shows the true nature of the positive impact of liquidity on fnancial performance, including direct positive efects and indirect positive efects through capital structure. In addition, our research results also show that non-fnancial enterprises that want to increase fnancial efciency need to pay attention to revenue growth, and non-fnancial companies with larger total assets (size) will have more advantages in increasing fnancial performance.
Epithelial cells, lining the skin and internal organs, play a crucial role as protective barriers and regulators of substance transport. Traditionally, these cells were not considered to employ electrical signaling for communication. However, recent investigations have unveiled that epithelial cells generate slow electrical signals, termed the "silent scream," in response to injury, thus challenging conventional views of intercellular communication. A recent experimental investigation provided compelling evidence for this phenomenon, demonstrating the ability of these cells to transmit electrical signals over considerable distances within the epithelium. The research utilized microelectrode array chips to precisely detect subtle electrical events in keratinocytes and Madin-Darby Canine Kidney (MDCK) cells, revealing spiking activity characterized by slow propagation speeds, distinct from the rapid action potentials of neurons. The mechanisms underlying this novel signaling are explored, focusing on the involvement of mechanosensitive ion channels, calcium signaling, and Adenosine triphosphate (ATP) release. Calcium ions, well-established intracellular messengers, appear to play a central role in this biological phenomenon. Integrating this newly discovered communication mode into the existing understanding of skin cell biology reveals a more intricate picture of how skin senses and responds to its environment. The implications of this finding extend to various facets of skin physiology and pathology, including wound healing, inflammation, and skin aging. In wound healing, where endogenous electric fields guide cell migration and promote repair, this unique type of electrical signaling potentially plays a crucial part. Furthermore, aberrant electrical signaling might contribute to chronic inflammatory conditions, and age-related changes in this signaling could underlie the functional decline observed in aged skin. The potential for other environmental stressors to trigger the epithelial-generated electric signals also warrants investigation. The exploration concludes by discussing potential technological applications, such as bioelectric sensors and enhanced wound healing therapies, and future research directions aimed at further elucidating the molecular mechanisms and functional roles of this non-excitable cell electrophysiology.
Medicinal plants have been known for thousands of years and are highly esteemed worldwide as a rich source of therapeutic agents for preventing and curing diseases. Nowadays, a large number of the population suffers from gallstones. The gall stones problem is increasing significantly due to changes in living styles and conditions, i.e. industrialization and malnutrition. Medicinal plants have been used for centuries due to their cultural acceptability, efficacy, safety and lesser side effects than synthetic drugs. The review aims to gather information on the plants utilized in various parts of society against gallstones. The information is useful for ordinary people and the scientific community to carry out further phytochemical, pharmacological and toxicological studies to discover new, effective and safer molecules against gallstones.
The samples of K1-xNaxNbO3 (X=0.4, 0.2, 0) ceramics (PSN) have been prepared by the conventional solid state reaction method and sintering process. The prepared samples have been characterized by XRD. All the prepared samples show orthorhombic structure at room temperature. Dielectric and Electrical properties of PSN system have been investigated in the temperature range 450C-2450C, and at 1MHz frequency. It is observed that dielectric constant, loss tangent and electrical conductivity increases with increasing temperature. Near the transition temperature dielectric constant, loss tangent and electrical conductivity of these samples show anomalous behaviour with temperature.
The wind tunnel experimental study has been carried out on a double delta wing of different geometrical configurations such as 80°/45°, 75°/45° and 70°/45° sweep angles given as Model I, Model II and Model III with various freestream velocities from 10 to 40 m/s with a step of 10 m/s in Hindustan Institute of Technology and Science, Chennai, Low Speed Wind tunnel (HITSLSWT). The experiment is conducted for the measurement of lift and drag forces using single component force balance. The investigation was done to look into the effects of changing the double delta wing's leading edge sweep angles. Three differentmodels have been tested at various angles of attack ranging from0° to +16° and 0° to −16° with 4° and four different freestream velocities based on the delta wing’s chord. It is observed that the influence of variation of leading edge sweep angles affects the performance of aerodynamic characteristics of themodel. The increase in angle in attack with increased velocity gives better aerodynamic performance. This paper provides good insight into the aerodynamic force measurement of double delta wing and the low-speed performance of the models.
With 450 questionnaires, the authors used SPSS software to analyze and found that the researched factors all had a positive impact on the development of community tourism services in Ha Giang province. In particular, the degree of influence on the development of CBT services in Ha Giang province in the order of importance is as follows: The level of organization and management of the tourism industry (QL), The participation of the community in the development of community tourism (TG), Tourism Resources (TN), Infrastructure Development (HT), Human Resource Training Development (NL). This result is the basis for us to choose appropriate solutions to improve the quality of community tourism services in Ha Giang province in the future.
International journal of business and social science research
To the editor, On April 24, 2025, the World Health Organization (WHO) issued an urgent call to reinvigorate global action to end malaria, releasing updated guidelines that reflect both progress and persisting challenges in combating this deadly disease. [1] This renewed guidance arrives at a critical juncture: global malaria cases have plateaued, progress is faltering, and health systems in endemic regions face increasing strain from drug resistance, climate change, and funding shortfalls.
Background: Although geriatric depression is widespread in primary health care (PHC), local studies on the prevalence of depression in elderly PHC patients appear to be scarce. This study aimed to determine the prevalence of depressive symptoms and some of the associated risk factors among elderly PHC patients. Methods: A cross-sectional study recruiting elderly people (60 years or older) from five PHC centers in Port Said Governorate was conducted. All participants had a structured interview. The long version of the geriatric depression Scale (cut-off point ≥10) was used in elders with a Mini-Mental State Examination ≥24. Results: About two-thirds of the total sample (65.7%) was female. The total prevalence of depressive symptoms was 49.4% of all subjects, more commonly in women (58.1% vs. 32.8%). Multiple regression analysis shows that female gender, high education, unemployment, low income, lonely life, loss of a close person, chronic diseases, tumor, iatrogenic medications, and depression history were the significant associated risk factors of depression in the studied elders after adjusting all previous variables in addition to age and marital status. Conclusion: Depressive symptoms constitute a significant health problem among older PHC patients in the Port Said governorate. Routine screening for depression of every elderly PHC patient is recommended for early detection.
This paper addresses global supply chain management (GSCM). The industry used to explore this topic is the automotive industry, as it is a core industry in the world economy, both in revenue generation and inefficiency. The paper explores both the positive and negative attributes of supply chain management, explores and analyses the gap between evaluation and implementation of improvements in supply chain management and then looks into the global issues affecting supply chain management and their solution.
Nowadays, the Internet of Things (IoT) has been used widely in our daily day to day life, starting from health care devices, hospital management appliances to a smart city. Most of the IoT devices have limited resources and limited storing capability. All the sensed information must have to be transmitted and to store in the cloud. To make a decision and for making analysis all the data stored in the cloud has to be retrieved. Making certain the credibility and security of the sensed information are much necessary and very important for the use of IoT devices. We tend to examine the proposed technique to be much secure than the existing one. In IoT, if the security is not ensured, then it may result in a variety of unsought issues. This survey resembles the overall safety aspects of IoT and debates the overall issues in the security of IoT.
The gold standard anesthesiologic procedure for urgent femur fracture surgery is Spinal Anesthesia. It is not always feasible because of patients' severe comorbidities and difficulties in optimizing drug therapy in the appropriate time frame such as discontinuation of anticoagulant drugs. The use of four peripheral nerve blocks (tetra-block) can be a winning weapon when all seems lost. We present, in this case series, three Caucasian adult femur fractures (an 83-year-old woman, a 73-year-old man, and a 68-year-old woman) with different and major comorbidities (cardiac or circulatory disorders on anticoagulants therapy that were not discontinued on time; breast cancer and others) underwent the same anesthesiologic approach in the urgent setting. Ultrasound peripheral nerve blocks, that is femoral, lateral femoral cutaneous, obturator, and sciatic with parasacral approach were successfully performed in all patients who underwent intramedullary nailing for intertrochanteric fracture. We evaluated the adequacy of the anesthesia plane, postoperative pain control with the VAS scale, and the incidence of postoperative side effects. Four peripheral nerve blocks (Tetra-block) can be alternative anesthesiologic management in urgent settings, in patients where drug therapy cannot be optimized, as in antiplatelet and anticoagulant therapy.
Behavioral finance theory highlights how psychological factors can lead to poor investment decisions, which may threaten investors' trust in the stock market, discourage investments, and hinder economic growth. This study aims to examine how behavioral finance factors, particularly herding bias and overconfidence bias, influence investment decision on the Indonesia Stock Exchange through risk perception. The research was conducted using an online questionnaire distributed to 120 Gen Z stock investors and analyzed using PLS-SEM. The results show that herding and overconfidence biases have a significant positive influence on risk perception. Both herding and overconfidence biases have indirect positive influences on investment decision through risk perception. Although overconfidence bias and risk perception can directly affect investment decision, herding bias fails to do so. These findings highlight the importance of considering an individual's behavioral biases and risk perception, while policymakers should devise strategies to mitigate their impacts; so that investors can benefit from investing, which may eventually lead to the growth of the national economy.
Background: The significance of healthcare wastes (HCWs) consists in their hazardous component, which constitutes real danger to public health. In Nigeria, healthcare waste management (HCWM) has remained a problem yet to be properly recognized and so addressed. The study aimed to sensitise health workers and the public on the need for proper management of HCWs, considering the public health implications of not doing so. Methods: The waste management systems of ten healthcare facilities (HCFs) were assessed, using a modification of the WHO rapid assessment tool. In each HCF, segregated wastes were collected daily for ten days and quantified by weighing, using a spring balance. Results: Administratively, the HCWM system was poor in the ten HCFs (40.6%). 70% of them had satisfactory waste segregation, 81%, good waste treatment, and 26.7% adequate transportation methods for waste. None of the HCFs had budget allocation for HCWM, and 90% had inadequate storage facilities. Mean waste generation was 1.81 kg/day, 0.23 kg/patient/day, 0.16 kg/bed/day, and proportion of infectious wastes 16.8%. Correlation between the number of patients and proportion of infectious waste, was positive, strong and significant (r=0.80, p=0.01), and between bed occupancy rate and proportion of infectious waste, was positive too, but weak, and insignificant (r=0.34, p=0.34). Conclusions: In view of the identified weaknesses of the ten HCFs in HCWM, budget allocations for HCWM, improving waste storage facilities and transportation, with strengthening of waste segregation, collection, and treatment, would help to ensure adequate HCWM in the HCFs.