Pharmacotherapy and associated risk factors for pulmonary tuberculosis

Tuberculosis is communicable disease which is common and often deadly infectious disease caused by mycobacterium tuberculosis. Tuberculosis continues to be a major public health problem in the world. The aim of this study is to assess prevalence and associated risk factors of pulmonary tuberculosis. Treatment and development of multidrug-resistant tuberculosis were also considered. Drugs for Pulmonary tuberculosis confirmed cases used in calculating tuberculosis prevalence in Libya which is obtained from archive department of Abu Seta Hospital. Data obtained from 427 files during 2019 determine the incidence and epidemiology of tuberculosis in Libya. For a total of 427 confirmed cases of pulmonary tuberculosis, about 75.0% of the cases were male and most of the patients (55.0%) were within the age group of 20 - 40 years old. Of the study patients, 114 patients (26.7%) were viral infected and most of the viral infected cases were in the age group of 20 - 40 years and the majority of this age group patients (n = 41, 53.2%) were infected with HIV/HCV, while the least percentage in this group age were infected with HIV/HBsAg (01.3%). Among 427 cases, 73 cases (17.1%) were comorbid with other chronic diseases. Of the 73 cases, 54 cases (74.0%) were diabetes mellitus whereas only 1.4% of them had bronchial asthma, Parkinsonism and renal failure. The drug therapy of active tuberculosis disease needs combination chemotherapy to escape the selection of naturally occurring drug-resistant mutants. Amongst current anti tuberculosis drugs, the rifamycins hold the highest potential for shortening treatment and improving effects. Prevalence of smear positive tuberculosis and bacteriologically confirmed that a high rate of tuberculosis among unemployed population. This study reported that the highest incidence rate is found in people who are smokers.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

The effects of aggressive-pornographic mass media stimuli

This chapter discusses the effects of stimuli that combine sexuality and aggression. It outlines the debate over aggressive versus nonaggressive pornography and discusses the frequency of aggressive pornography and bases for concern. Aggressive pornography and sexual arousal is explored in the chapter wherein initial findings, victim's responses, individual differences, context of assessment, and conclusions are discussed. The chapter reviews the effects of aggressive pornography on responses other than aggression wherein it has discussed about changes in sexual responsiveness, fantasies, and perceptions and attitudes. The effects of aggressive pornography on aggression are explored in the chapter wherein research findings are discussed in detail and summary of effects on aggression, theoretical analyses, and the construct validity of assessing aggression are also described. The data across the laboratory and field experiments discussed in this chapter raise a variety of theoretical and empirical issues that should be addressed in future research. Particularly noteworthy are questions concerning stimuli, subject, and setting characteristics.

John Dolores John dolores

Strategic marketing - blog entry

Marketing refers to the actions that elevate customer value by motivating them to purchase the organisation's products or services (Kusumadewi, 2019). An organisation with strong capabilities must exhibit strong marketing capacities to effectively introduce its offerings to new markets (Lee and Falahat, 2019). Marketing strategies are part of an organisation's corporate strategy, which refers to the set of choices an organisation makes to develop and capture value across its business over time. As corporate strategy essentially drives financial performance (Sull et al., 2018), effective marketing strategies must be selected to ensure the organisation's attainment of objectives and long-term success.

Zamzam Abdelazim Zamzam abdelazim

Anti-inflammatory potential of medicinal plants

Inflammation is said to be a healthy component of the body immune system's reaction. Inflammation is characterised by four key symptoms: pain, redness, heat or warmth and swelling. As secondary metabolites, plants may produce a wide range of phytochemical compounds, which possess anti-inflammatory characteristics. Herbal remedies are important therapies for a wide range of ailments all over the world. There are around 7 500 species of medicinal plants, including representatives from over 17 000 flowering plant species. Even when synthetic chemistry has developed out their expectations, the use of natural ingredients in the manufacture of drugs used in contemporary medicine is unparalleled. By interfering with the biology of inflammation, anti-inflammatory medications may assist to minimise tissue damaging and increase patient’s comfort. Because of the bulky figure of species reachable for study, the effective development of novel naturally taking place anti-inflammatory drugs is mostly dependent on a multidisciplinary approach to discovering new chemicals. Despite the statistic that many review papers have been produced in this field, the conventional of them simply examined the issue from an area perspective. Several non-steroidal anti-inflammatory drugs have been shown to reduce inflammation and pain by decreasing the isoform of the cyclooxygenase enzyme's digestion of arachidonic acid, hence lowering prostaglandin production. Non-steroidal anti-inflammatory drugs have a host of harmful effects. There are, however, medicinal herbs with anti-inflammatory pharmacological properties that have few or no negative effects.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

Analgesic and antiemetic activities of ficus exasperata vahl., and cleome ciliata schmach and thonn

The present investigation is an attempt to evaluate the analgesic and antiemetic activities of Ficus exasperata and Cleome ciliata leaves methanolic extract by using the chick emesis model (oral treatment) and acetic acid-induced writhing test (intraperitoneal treatment) in mice, respectively. The antiemetic activity (150 mg/kg b.w., of extract) was carried out by using chlorpromazine (150mg/kg) as standard antiemetic drug. The analgesic activity (250 mg/kg b.w. of extract) was performed using aspirin (150mg/kg) as a standard analgesic drug. The results showed significant analgesic and antiemetic effects.

Dr. Salman Ahmed Dr. salman ahmed

Footprints of swine influenza h1n1 and h3n2 in pigs from southern kaduna, nigeria

Influenza A virus presents a significant public health burden worldwide, with the 1918 Spanish flu pandemic being the most dramatic example. Swine influenza viruses can be transmitted to humans through occupational exposures and in live pig markets. Novel variants can emerge in pigs because they can be infected by human, avian and swine strains. This study was carried out to determine the seroprevalence and serotypes of swine influenza in pigs from a major slaughter slab in southern Kaduna. Using competitive ELISA and haemagglutination-inhibition (HI) assays, 305 swine sera were analysed. The result showed an overall seroprevalence of 28.20% (n=86), with H3N2 7.87% (n=24) emerging as the most dominant subtype in circulation. Concurrent antibody detection of H1N1 in 5.26% (n=16) was also detected in boar 2.62% (n=8) and sows 2.62% (n=8). This study revealed swine Influenza H1N1 and H3N2 serotypes are in circulation in pigs in Kaduna State, and that reassortment in the instance of co-infection of swine host is possible.

Bitrus Inuwa Bitrus inuwa

The main problems at assessment of qualitative and quantitative indices of state activity

The article analyzes the main problems of making an assessment of public administration activities, gives important question and makes main ways of experiences of assessing criteria of public administration. This the article is also devoted to the analysis of the essence of efficiency and quality of public administration in the world and studies the main conceptual models of efficiency of public administration, the definition of types of efficiency and identification of the main problems when forming criteria for evaluation of efficiency and quality of the government

Ikboljon Odashev Mashrabjonovich Ikboljon odashev mashrabjonovich

Alpha-numeric analysis of engineers cum arbitrators - numerology

ABSTRACT “Numbers are the highest degree of knowledge. It is knowledge itself.”- Plato “The world is built on the power of numbers.” Pythagoras “Everything around you is numbers.” Shakuntala Devi. The date, we were born on, was not an accident. Each number in our date of birth is connected with certain energies and vibrations. Similarly, each and every letter in our name (first as well as full name) also has particular frequency, energies and vibrations. The combined and correlated energies of numbers and letters of an individual reveal about the past, present and future. The careful study of these universal divine energies can reveal, who you are, why you are here, where are you going and how will you get there. In other words what is your personality, nature, thinking, and what is your future in terms of family career relationships and finances etc. In this study, an attempt has been made to analyze -How certain patterns of name numbers and date of birth related core numbers can emerge as a directional guide for an individual to choose any specific career/profession (by studying the patterns of over 1100+ date of births and names of the Engineers cum Arbitrators).

Jyotsnaa G Bansal Jyotsnaa g bansal

Parental perception about western cartoon on child’s mental health in pakistan

The purpose of this study is to explore the impacts of foreign cartoons programs on the social behavior and attitude of Pakistani Children. It is forecasting different cartoon programs 24/7; hence, children spend most of their leisure in front of the television. All these cartoon characters affect the social life and psyche of the children and induce positive and negative mannerism in their daily lifestyles. It has found that one of the most disturbing factor is that the ferocity in children today is increasing rapidly due to following their favorite violent cartoon characters which are even different from their culture and societal norms. The issue is violence is what they see in every cartoon program in one or the other way. Their Guardians are unaware that these cartoons they let their children watch are destroying their parenting as negative forces are attacking the innocent minds of this generation. The study gives the insight of why and what is happening with non-parametric statistics studied and used for thorough analysis. The behavioral outcome of the kids like, imitating their preferred animation character, utilizing various dialects, watching the TV as opposed to deciding on outdoor games and being difficult about getting precisely the same outfits and embellishments as their adored character. This contextual analysis features the disturbing circumstance that guardians are uninformed of. There is something other than mimicking the particular character. The only traits of watching these foreign cartoon characters is that it might damage their own customs and they wildly become to believe these characters as their role models.

Zaki hasan

New dimension in higher education in india

Higher Education has an important role in the task of rebuilding a nation and it pavCes the way for overall development of a nation. The twentieth century has witnessed several revolutions like Green revolution, White revolution, I.T revolution, so on and so forth, taking human civilization to new heights. At the start of 21st century, we gave a lot of importance given to higher education. Every country realized the value of higher education and the benefits that accrue from it. “The social demands for higher education continue to increase. The inabilities of the state to support this growing demand result in new financing arrangements for higher education. The recent reforms in this area could be broadly divided into two categories: the privatization of public institutions and the establishment of private institutions of higher education. Privatization implies the application of market principles in the operation of public institutions, while ownership rests within the public domain. Promotion of the private sector implies the growth and expansion of the non-state sector in higher education, and very often this sector does not rely on state funding for its growth and expansion. Both of these measures have paved the way for market operations in higher education

Dr Gedam Kamalakar Dr gedam kamalakar

Behavioural effects of vitamin c with haloperidol in mice

Vitamin C causes a significant change in pharmacological effects of some drugs which may lead to unpredictable responses. Vitamin C-haloperidol interaction has not been confirmed in vivo. This study was aimed to investigate the influence of vitamin C on some pharmacological effects of haloperidol (extrapyramidal side effects caused by the antipsychotic haloperidol). Albino male mice (n = 24, body weight of 20 - 40 gm) were divided into four groups and each of consists of six mice. Group I (control): given 1% Tween 80 solution, group II: given vitamin C in a dose of 100 mg/kg, group III: given haloperidol (2 mg/kg), while group IV: given a combination of vitamin C and haloperidol. All the treatments were given by intraperitoneal route of administration. Three sub-acute doses of different treatments were given at 24:0, 5:0, 1:0 hour before scoring. Parameters scored were catalepsy, ptosis, rigidity and akinesia. The experiment was repeated using vitamin C in a dose of 500 mg/kg. Both doses of 100 and 500 mg/kg of vitamin C significantly antagonized the effect of haloperidol by decreasing all the tested parameters. The results indicate that vitamin C decreases extrapyramidal side effects caused by the antipsychotic haloperidol and show that it successfully decreases catalepsy, ptosis, rigidity and akinesia in mice.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

Plants of family lamiaceae: a promising hand for new antiurolithiatic drug development

Urolithiasis has been a common problem for centuries and has a high recurrence. This review covers the forty-nine (49) antiurolithiatic plants of the family Lamiaceae used in 11 countries. Hopefully, this review will be helpful for the general public and attract the scientific world for antiurolithiatic drug discovery.

Dr. Salman Ahmed Dr. salman ahmed

Bleomycin pulmonary toxicity in patients with germ cell tumors treated with bleomycin containing regimens: experience with 4 cases

Background: Information on Bleomycin pulmonary toxicity (BPT) in Qatar is scarce. The aim of this study was to estimate the prevalence of BPT and to describe its clinical significance and outcome in germ cell tumor (GCT) patients who received bleomycin-containing regimens.Methods: This retrospective cross-sectional study was conducted at the National Center for Cancer Care and Research. It included all patients diagnosed with GCT and treated with a bleomycin-containing regimen between January 2002 and December 2008 Results: We identified fourteen patients with GCT who received bleomycin containing regimen. Four of them (28.5%) had developed BPT, and they were males with mean age of 39.3±8.3 years (range: 25-46 years). The calculated creatinine clearance before treatment was normal in the 4 cases. Evaluation of the chest computed tomography scan before starting bleomycin containing regimens revealed that none of our patients had pre-existing parenchymal lung disease. The mean cumulative bleomycin dose was 187.5± 153.7 U, while the mean time to onset of BPT was 3.5±2.1 months. Once the diagnosis of BPT was established, bleomycin was discontinued in the four patients and short courses of dexamethasone were administered. Two patients (50%) died, while one patient survived with a fibrosis sequel, and the fourth patient recovered without a fibrosis sequel. Conclusion: BPT is one of the life-threatening side effects of this drug that every doctor should be aware of when treating GCT, therefore, a high index of suspicious is needed for early recognition of BPTs.

Karishma Karishma

Near infra red spectroscopic analysis of macrotyloma uniflorum (lam.) verdc., phaseolus lunatus linn. and phaseolus vulgaris linn.

The present study is designed to determine the types of secondary metabolites in three selected seed powders using a fast, reliable, and non-destructive Near Infra Red spectroscopic analytical technique. NIRS analysis of Macrotyloma uniflorum (Lam.) Verdc., Phaseolus lunatus Linn., and Phaseolus vulgaris Linn., seed flours were used to qualitatively evaluate secondary metabolites. The fine powder of crude drug was directly applied to FOSS XDS near the infrared Rapid Content Analyzer. The adequately filled powdered sample in a disposable glass silicate vial closed with a plastic lid was centrally placed onto the Foss Rapid Content Analyzer sample presentation glass. The scanning of samples at ambient temperature gives NIR spectra within 30 seconds. The major proposed compounds in M. uniflorum were 3,4-dihydroxybenzoic acid, caffeic acid, chlorogenic acid, ferulic acid, gallic acid, kaempferol, linolenic acid, niacin, quercetin, sinapinic acid, syringic acid, and vanillic acid. Whereas coumaric acid, fructose, galactose, L-serine, raffinose, stachyose, sucrose, threonine, and tyrosine were detected in P. lunatus, and the NIR suggested the presence of caffeic acid, ferulic acid, sinapinic acid, phytic acid, leucine, and valine in P. vulgaris. NIRS is an advanced innovative technology extensively used in chemical, food, petrochemical, and pharmaceutical industries for rapid and reliable standardization. The present study revealed an excellent correlation to conclude that flour samples of all three legume seeds could be added to the food system to achieve nutritional and functional benefits.

Dr. Salman Ahmed Dr. salman ahmed

The prospect of legal education: an india overview

Education in India is losing its relevance. This seems much more applicable to the situation in the present day of legal education. This essay aims to focus on two aspects of legal education. Whilst, on one hand, it aims to provide details of the existing legal education system on the other, it aims to drive more attention to the various improvements and developments that are needed. The essay firstly shall describe the existing legal education system. It shall analyze and assess the curricula that are available for the various undergraduate law degrees available in India. It aims to provide an understanding of the perceived distinctions between the three-year law degree and the five-year law degree. As a second aspect, the essay aims to explore options to further the quality of legal education in India by considering examples of various law schools or colleges of law across the world that have consistently proven themselves as a cut-above not legal education and research in their global scale. Also, from the learnings of the gaps in the curricula of the law degrees as discussed previously, the essay shall provide suggestions on the various plausible collaborations with foreign law schools and universities for the benefit of the Indian law schools and colleges of law. As a third and final aspect, as a measure to curb fake or bogus law schools or colleges of law within India and to enhance the employability of law graduates in India at par with those across the globe, the essay aims to provide suggestions applicable for the present-day legal education scenario.

Hari hara sudhan r

The religious practices of vietnamese catholic youth: the case of the diocese of xuan loc

Every religion includes a whole series of beliefs and practices and we should start by concentrating our attention on religious practices to understand a religion. This paper intended to clarify the religious practices of Vietnamese Catholic Youth. Based on the theory of Glock and Stark and by using survey method, descriptive statistics, this is the first study to demonstrate the religious practices of youths in a diocese of Vietnam. This issue considered as an interesting research topic in the context of Vietnamese research because it explores youths lives from a different perspective by focusing on the micro level of analysis. The respondents in this study were total of 388 young adults between 18 and 30 years of ages from 24 parishes who were randomly selected through Probability Proportional to size sampling method. The findings of the research indicate that the ritualistic dimension of religiosity among Vietnamese Catholic youth is still so high in the context of change in Vietnam

Le Minh Tien Le minh tien

Surah mulk

In the name of Allah, Most Gracious, Most Merciful. Blessed be He in Whose hands is Dominion; and He over all things hath Power;- He Who created Death and Life, that He may try which of you is best in deed: and He is the Exalted in Might, Oft-Forgiving;- He Who created the seven heavens one above another: No want of proportion wilt thou see in the Creation of (Allah) Most Gracious. So turn thy vision again: seest thou any flaw? Again turn thy vision a second time: (thy) vision will come back to thee dull and discomfited, in a state worn out. And we have, (from of old), adorned the lowest heaven with Lamps, and We have made such (Lamps) (as) missiles to drive away the Evil Ones, and have prepared for them the Penalty of the Blazing Fire. For those who reject their Lord (and Cherisher) is the Penalty of Hell: and evil is (such), Destination. When they are cast therein, they will hear the (terrible) drawing in of its breath even as it blazes forth, Almost bursting with fury: Every time a Group is cast therein, its Keepers will ask, “Did no Warner come to you?” They will say: “Yes indeed; a Warner did come to us, but we rejected him and said, ´Allah never sent down any (Message): ye are nothing but an egregious delusion!´” They will further say: “Had we but listened or used our intelligence, we should not (now) be among the Companions of the Blazing Fire!” They will then confess their sins: but far will be (Forgiveness) from the Companions of the Blazing Fire! As for those who fear their Lord unseen, for them is Forgiveness and a great Reward. And whether ye hide your word or publish it, He certainly has (full) knowledge, of the secrets of (all) hearts. Should He not know,- He that created? and He is the One that understands the finest mysteries (and) is well-acquainted (with them). It is He Who has made the earth manageable for you, so traverse ye through its tracts and enjoy of the Sustenance which He furnishes: but unto Him is the Resurrection. Do ye feel secure that He Who is in heaven will not cause you to be swallowed up by the earth when it shakes (as in an earthquake)? Or do ye feel secure that He Who is in Heaven will not send against you a violent tornado (with showers of stones), so that ye shall know how (terrible) was My warning? But indeed men before them rejected (My warning): then how (terrible) was My rejection (of them)? Do they not observe the birds above them, spreading their wings and folding them in? None can uphold them except (Allah) Most Gracious: Truly (Allah) Most Gracious: Truly it is He that watches over all things. Nay, who is there that can help you, (even as) an army, besides (Allah) Most Merciful? In nothing but delusion are the Unbelievers. Or who is there that can provide you with Sustenance if He were to withhold His provision? Nay, they obstinately persist in insolent impiety and flight (from the Truth). Is then one who walks headlong, with his face grovelling, better guided,- or one who walks evenly on a Straight Way? Say: “It is He Who has created you (and made you grow), and made for you the faculties of hearing, seeing, feeling and understanding: little thanks it is ye give. Say: “It is He Who has multiplied you through the earth, and to Him shall ye be gathered together.” They ask: When will this promise be (fulfilled)? – If ye are telling the truth. Say: “As to the knowledge of the time, it is with Allah alone: I am (sent) only to warn plainly in public.” At length, when they see it close at hand, grieved will be the faces of the Unbelievers, and it will be said (to them): “This is (the promise fulfilled), which ye were calling for!” Say: “See ye?- If Allah were to destroy me, and those with me, or if He bestows His Mercy on us,- yet who can deliver the Unbelievers from a grievous Penalty?” Say: “He is (Allah) Most Gracious: We have believed in Him, and on Him have we put our trust: So, soon will ye know which (of us) it is that is in manifest error.” Say: See ye?- If your stream be some morning lost (in the underground earth), who then can supply you with clear-flowing water?

Kamal Singh Kamal singh

Natural antiemetics: an overview

Emesis encompasses the forceful expulsion of the stomach's contents via the mouth or sometimes the nose. The adverse effects of currently available anti-emetic agents potentiate the natural product researchers to explore natural anti-emetics with fewer side effects. The presented communication reviews the anti-emetic effect of two hundred and forty-five plants belonging to seventy-eight families in different parts of the world. It also outlined the anti-emetic effect of plant extracts and isolated secondary metabolites studied through a variety of animal models of emesis. The reported anti-emetic plants in different countries and cultures and the scientific studies on extracts may help in the identification of promising single chemical compound(s) that may be used as potential leads for developing safe anti-emetic agents in future. Moreover, the reported secondary metabolites having the same effect may open the door for the search for the same secondary metabolites from other natural sources. This review will provide useful information for discovering natural anti-emetic compounds and fill the gaps in knowledge.

Dr. Salman Ahmed Dr. salman ahmed

Behavior of small states from the perspective of international relations theory: an analysis of south china sea

Territorial disputes in the South China Sea have long been one of the most critical and complex issues of security between south-east Asian states and China. The competition for maritime rights has emerged as the most important security issue in the east Asia. The powerful states have a tendency for domination. The smaller states may not show their dominating behavior over other states, but they have tendency to maximize their relative power by making alliance with great power or by other means. Since the smaller states are not capable enough individually to ensure their own security or to use military force against threatening power, they have tendencies to join in alliances or in other words to create balance of power to ensure their own security. This study attempts to analyze the behavior of small states and to find out which theory matches with the behavior. The behavior of small states like Vietnam and the Philippines cannot be well-explained by the realist approach. They behave to make their existent clear and safeguard themselves only. Making allies with great powers as well as economic ties simultaneously with other economic powers render their behavior of having peaceful coexistent with everyone.

Muhammad faruq-uz-zaman

Online assessment of primary students’ cognitive, psychomotor, and affective domains: practices from urban and rural primary schools in indonesia

This study intends to describe assessment strategies for young students' online learning. The participants in this descriptive qualitative study were 15 primary school principals and 35 teachers teaching Years 4 and 5 in urban and rural schools on the island of Lombok, West Nusa Tenggara Province, who volunteered their participation after undergoing comparable procedures. Using operational concepts of assessment of learning for online learning, class observation, and interview were organized. The content and structure validity of the measures were evaluated in accordance with the developmental periods of young learners. The findings showed that the teachers assessed the primary students' cognitive, psychomotor, and affective domains interactively during the online class meetings, in their portfolio, and through attitude direct observation. Several assessment strategies were advocated to circumvent the shortcomings of online learning. A criterion-referenced evaluation was used to conduct the analysis. The theoretical implications of the findings suggest that the various assessment procedures adopted have decreased the negative washback of online exams; however, further research is required to determine the consistency of the outcomes of online tests with other types of evaluation.

Darrel Ocampo Darrel ocampo

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