Melioidosis is an infection that causes high morbidity and mortality. Predisposing risk factors include diabetes mellitus (DM) and immunocompromised state. We report a case of septic shock secondary to bacteremia caused by Burkholderia pseudomallei in a patient who is supposed to be previously healthy and subsequently diagnosed with DM and glucose-6-phosphate dehydrogenase (G6PD) deficiency. He completed 17 days of intravenous antibiotics followed by a 12-week course of oral trimethoprim/sulfamethoxazole. We postulate that G6PD deficiency could be a risk factor for melioidosis.

Karishma

This conceptual paper critiques the overgeneralized adoption of hybridity in translation studies, exposing its theoretical circularity, lack of actionable strategies and weak methodological grounding. Although hybridity is often conceptualized as a means of cultural negotiation, its translation-specific application remains underdeveloped. Bhabha’s “third space” metaphor is frequently cited but without translating it into actionable strategies, with existing applications being viewed either as too niche or essentializing cultural binaries. Therefore, the ethical dilemma of striking a balance between source text authenticity and target text accessibility remains unresolved, with actual translation decisions often oscillating between two extremes, either reinforcing or subverting hegemonic structures. To close this gap, this research proposes a dynamic hybrid model which puts practical strategies into action to overcome theoretical limitations of hybridity. The model draws on Joseph Malone’s practical strategies to combine foreignization and domestication in a dynamic framework which enables translators to maintain essential cultural elements while achieving clarity. The model presents a practical hybrid approach to literary translation, one that maintains a balanced harmony between faithfulness and accessibility.

Faisal khalifa

Introduction: The university experience often brings various personal and academic challenges that can negatively impact students’ mental health. This research aimed to evaluate the effect of a mindfulness program on stress, anxiety, depression, sleep quality, social support, and life satisfaction among university students. Methods: A quasi-experimental study was conducted with 128 participants, divided into experimental and waiting list control groups. The experimental group participated in a mindfulness meditation program consisting of 12 weekly sessions. Pre-test and post-test measurements were performed using the Perceived Stress Scale (PSS-10), the Zung Self-Rating Anxiety Scale (SAS), the Zung Self-Rating Depression Scale (SDS), the Pittsburgh Sleep Quality Index (PSQI), the Medical Outcomes Study Social Support Survey (MOS-SS), and the Satisfaction with Life Scale (SWLS) to assess the variables. Results: The experimental group showed statistically significant differences between the study phases and the groups after the intervention for all the variables examined (p < 0.05). The effect sizes calculated using the HC3 model were stress (η2 = 0.376), anxiety (η2 = 0.538), depression (η2 = 0.091), sleep quality (η2 = 0.306), social support (η2 = 0.704), and life satisfaction (η2 = 0.510). The mindfulness program was shown to be effective in reducing levels of stress, anxiety, and depression while also improving sleep quality, social support, and life satisfaction in college students. Conclusion: These findings indicate that mindfulness meditation may be valuable for enhancing psychological well-being in educational settings.

Paul alan arkin alvarado-garcia

The present review shares an updated data on the botany, distribution, traditional medicinal uses, phytochemistry and pharmacology of Phaseolus lunatus L. All provided information was obtained through Google Scholar, Pubmed, Sci Finder, Scirus, Web of Science and library search.

Dr. salman ahmed

Kepatuhan terhadap terapi farmakologi merupakan kunci utama pengobatan penyakit diabetes, tetapi belum mendapat perhatian penuh oleh para klinisi. Beberapa systematic review faktor kepatuhan telah dilakukan di beberapa kawasan negara. Namun, tidak menampilkan studi dari Indonesia. Penelitian ini bertujuan untuk meninjau secara sistematis faktor-faktor yang dapat memengaruhi kepatuhan minum obat diabetes melitus (DM) di Indonesia. Systematic literature review dilakukan melalui pencarian pada database jurnal Nasional (Garuda dan Sinta) dan Internasional (PubMed dan Science Direct). Penelitian yang sesuai dengan kriteria inklusi dan dipublikasikan pada Januari 2011 – Desember 2020. Kualitas penelitian dinilai menggunakan panduan SQAT. Metode pelaporan penelitian menggunakan pedoman PRISMA. Faktor kepatuhan diklasifikasikan berdasarkan domain faktor kepatuhan menurut World Health Organization (WHO). Sebanyak 370 artikel ilmiah penelitian dari database Garuda (n=36); Science Direct (n= 108); PubMed (n= 18); Sinta (n= 208). 341 artikel penelitian dieksklusi, 29 artikel skrining full text, dan 16 artikel penelitian memenuhi kriteria inklusi untuk dianalisis. Faktor yang memengaruhi kepatuhan minum obat diabetes adalah faktor sosial dan ekonomi (penghasilan, tingkat pendidikan, dan pekerjaan), faktor tenaga dan sistem kesehatan (tenaga kesehatan), faktor terapi pasien (jumlah obat diabetes, frekuensi minum obat, dan produk obat), faktor penyakit pasien (kadar gula darah, durasi penyakit), faktor pasien (jenis kelamin, faktor emosional, dukungan sosial, tingkat pengetahuan, dan kepuasan pengobatan), dan faktor pengelolaan penyakit (konseling dan edukasi farmasi). Faktor yang memengaruhi kepatuhan minum obat DM di Indonesia sangat beragam, dan multi faktor. Faktor tersebut dapat berfungsi sebagai target intervensi yang relevan. Para klinisi perlu mempertimbangkan penyesuaian frekuensi minum obat dan pemberian dukungan sosial kepada pasien DM.

Much ilham novalisa aji wibowo

The study examined public-private sectors’ collaboration in human resource management and curriculum development in the administration of public senior secondary schools in Rivers State. The study adopted the descriptive survey design. Two research questions and two hypotheses guided the study. The population of the study comprised 281 principals in the 281 public secondary schools in Rivers State. The proportionate stratified random sampling technique was used to draw up sample of 259 principals representing 92.2% of the population of the study (211 male principals and 70 female principals). An instrument titled: Public-Private Sectors’ Collaboration for School Administration Questionnaire (PPSCSAQ) designed in the modified 4-point Likert Scale with a reliability index of 0.87 was used for data collection. The face and content validities were ensured. Mean and standard deviation were used in answering the research question while z-test was used in testing the hypotheses at 0.05 level of significance. The finding of the study showed that to a high extent public-private sectors collaborate in human resource management and curriculum development in the administration of public senior secondary schools in Rivers State. It was recommended among others that the government should provide enabling environment and formulate favourable policies to sustain public-private sectors’ collaboration as it ensures effective human resource management in the state.

Fxintegrity publishing

Host plant resistance is an important tool for minimizing the losses in pigeonpea due to spotted pod borer, Maruca vitrata, which is the most threatening hidden pest of pigeonpea crop. Experiment was carried out to study the morphological and chemical traits in pigeonpea associated with expression of resistance to M. vitrata and their incidence in different sowing dates. The incidence of M. vitrata varied significantly among different sowing dates. Crop sown on D2 (1st week of July) resulted in maximum pod infestation by M. vitrata (13.1%). Minimum pod infestation (2.3%) and (2.9%) was recorded in D4 (3rd week of July) and D1 (3rd week of June) sown crop, respectively. Among different varieties, AL-201 registered lowest pod infestation (4.3%) as compared to Pusa-992 (7.9%). The non-glandular (type A), and glandular (type B) pod trichome density of top, middle and lower canopy of the plant and the pod wall thickness was responsible for the resistance to M. vitrata. Whereas, non-glandular (type C) pod trichomes, pod length, seed width and number of seeds per pod were associated with the susceptibility to spotted pod borer. Expression of resistance to M. vitrata pod infestation was associated with low amounts of crude protein and total soluble sugar and higher amount of fat content, phenol content and tannin content of seed as well as pod wall

Dr. babu lal jat

2-Pyrazolines are well known, and important nitrogen-containing five-membered heterocyclic compounds which belong to the family of azoles and have been found to possess considerable activities, like anticancer, antibacterial, antifungal, immunosuppressant and antiamoebic activity. In the present work, ten novel pyrazolines were prepared from chalcones, characterized and evaluated for their antibacterial activity against Staphylococcus aureus and Escherichia coli using Ciprofloxacin as standard and using DMSO as a solvent. Their activity was evaluated by measuring the zone of inhibition in mm. All the compounds exhibited antibacterial activity against Staphylococcus aureus and Escherichia coli. Among ten derivatives of compounds synthesized, the derivative with 2-chloro and 4-chloro substituted phenyl rings attached to pyrazolines exhibited the highest activity against both types of organisms. The derivatives with an unsubstituted phenyl group attached to pyrazolines exhibited comparatively less activity. Thus it can be concluded that pyrazolines containing substituted phenyl groups are effective broad spectrum antibacterial agents, and they can be developed as effective antibacterial agents.

Vinod b

In present study various fungicides were screened against blast (leaf and neck) and sheath blight disease of rice. Among them, Conika 50% WP (Kasugamycin 5% + Copper Oxychloride 45% WP), Dhanucop Team (Tricyclazole 75% WP) and RIL-068/F1 48 WG (Kresoxim methyl 40% + Hexaconazole 8% WG) were found effective against blast diseases. While, the seed treatment fungicide Isotianil SC 200 and its combination with Trifloxystrobin 500 SC were found least effective against leaf and neck blast diseases. However, in case of sheath blight, Thifluzamide 24% SC, RIL-068/F1 48 WG (Kresoxim methyl 40% + Hexaconazole 8% WG), Propiconazole 25% EC (Tilt), Tricyclazole 75% WP (Beam) and a new combination fungicide, Fluxapyroxad 62.5 g/l + Epoxiconazlle 62.5 g/l EC (Adexar w/v EC) were found effective.

Veerabhadraswamy al

All the people who need loan may turn to their local banks, credit unions or peer to peer lenders. Every lending institution has its own advantages and drawbacks. In this scenario credit risk management becomes increasingly important element as the same is concerned with managing the financial debts and safeguarding the interest of the banks. The purpose of credits given by banks is to earn interest and make profits. The important function of credit management is to decide how much credit should be given to the borrower and ensuring compliances with the credit terms of repayment and avoid Non-Performing Assets (NPA) to the banks. Credit risk is the biggest risk the bank faces by the virtue of nature of business, inherits. The ability of commercial banks to formulate and adhere to policies and procedures that promote credit quality and curtail non-performing loans is the means to survive in the stiff competition. Inability to create and build up quality loans and credit worthy customers leads to default risk and bankruptcy as well as hamper the economic growth of the country

Shaila kamath

Aerva lanata species belonging to Amaranthaceae family (a.k.a mountain knot grass/Gorakha Ganga is a perennial shrub. It is self-pollinating, bisexual plant having globose like structure has various phytochemical constituents. Among the 28 species of Aerva, medicinal properties are likely to be present in Aerva lanata, Javanica and Persica varieties. Traditionally it was used in treating cough, dysuria, hemiplegic migraine and kidney related disorders. Flavonoid glycosides such as Kaempferol, Isorhamnetin, quercetin, flavanone are major phytoconstituents and minor constituents are apigenin, narcissin, ferulic acid, syringic acid and vanillic acid. Alkaloid glycoside includes Ervine, aervine etc. Aerva lanata has much more beneficial activities like demulcent, diuretic, ulcer wounds, rheumatism, Anti-malarial. Pharmacological studies included that aerva species has beneficial properties of antimicrobial, anti-urolithiasis, antiulcer, anti-asthmatic, acute kidney injury, anti-diarrheal activity, antioxidant, antihyperglycemic, hypolipidemic and antiulcer. Aerva lanata has promising role in the treatment of various diseases and metabolic disorders due to its higher antioxidant effect and other such constituents thereby providing better healthcare. Various such constituents are to be analyzed properly and to ensure that it was suffice to exhibit the pharmacological activity. Analytical methods are to be used promptly to find various concentration of substances present in the alcoholic extract of Aerva lanata plant.

Ankul singh

Higher education is leadership education. The values and virtues practiced in universities heavily influence the future leaders. Many institutions of higher education simultaneously show excellence in academic subjects, are green campuses with manifold ethics curricula, are active members in community engagement, and also are adept in providing value orientation to all stakeholders. It is universally felt that the status of teaching profession requires to be raised to ensure its dignity and integrity. Accordingly, it is considered necessary that there should be a code of ethics which may be evolved by the teaching community itself for its guidance. There are five major areas of professional activities which encompass the work of a teacher. For each of these areas certain principles have been identified to serve as guidelines for teacher’s conduct. HUMAN VALUES Basic human values refer to those values which are at the core of being human. The values which are considered basic inherent values in humans include truth, honesty, loyalty, love, peace, etc. because they bring out the fundamental goodness of human beings and society at large.

Kamal singh

The use of performance feedback in the workplace has gained popularity over the years, yet school heads have been challenged in providing it to teachers. In the initial interview, they shared that evaluation results can impact teachers’ motivation, and that feedback should be done carefully. However, they failed to clearly articulate a specific mechanism that had been applied in this vital role. Also, no studies have provided clear detail on the feedback mechanism used by school heads in the past. For this reason, a study explored the feedback mechanisms employed by school heads in conveying the performance evaluation results to teachers. This study employed a narrative inquiry, and interviews were conducted with five school heads and five teachers who were chosen purposively for this research. Responses were recorded using a voice recorder. These responses were transcribed and analyzed using thematic narrative analysis. Based on transcripts, the study identified six emergent themes, such as conversational (one-on-one), relational, reflective, technical, reinforcing, and properly situated mechanisms in conveying performance evaluation results to teachers. Thus, a new feedback mechanism framework was developed.

Manuel caingcoy

During Movement Control Order (MCO) of COVID-19, many information has been disseminated through both traditional and social media. Some of that information was credible and came from reliable sources while other information was fake and included misinformation, disinformation, and infodemic. The people needed credible information rather than fake one in this critical time. This study aimed to explore the credibility of media, information sources, the main issues, and preferred communication patterns and method of works perceived by Malaysians during MCO. A total of 300 questionnaires were distributed, and 210 were returned. The results of this study showed that the majority of respondents 69% relied on new media as their main source of information compared to 30.9% who relied on traditional media. However, a total of 64.8% of respondents considered traditional media as more credible and accurate compared to 35.2% for new media. Additionally, the main concerns and issues followed by respondents on media were health, economic, social, education and others. Finally, a total of 55.7% preferred face to face communication compared to 44.3% who preferred online communication. A total of 51% of respondents preferred to work from the workplace or office compared to 49% who preferred to work from home. Television played a significant role during the pandemic period due to its high credibility as perceived by Malaysians. The main intriguing implication of this study is considering the traditional media as more credible than social media by the Malaysians although the social media was their main source of information.

Mohammed fadel arandas

This paper investigates the transformative potential of Indian Knowledge Systems (IKS) in modern business and management practices, aligning with India's vision for "Viksit Bharat 2047"—a roadmap toward becoming a developed nation by 2047. Integrating ancient Indian wisdom with advanced Artificial Intelligence (AI) provides an innovative framework for enhancing decision-making, sustainability, and innovation across diverse industries. This study aims to incorporate key IKS principles such as holistic management, ethical leadership, and community-centered business models into AI-driven methodologies to create a forward-thinking approach in Indian business contexts. Using a mixed-method research design, the study combines qualitative insights from traditional Indian texts with quantitative analysis of case studies where IKS principles are applied in contemporary businesses. The findings reveal that concepts like ―Dharma‖ (ethical responsibility), ―Artha‖ (resource management), and ―Karma‖ (action-driven leadership) play a crucial role in corporate governance, social responsibility, and achieving sustainable development goals when combined with AI's analytical power. This synergy addresses current challenges, including environmental sustainability, social equity, and ethical governance. The research demonstrates that a balanced integration of AI and IKS can foster inclusive and sustainable growth, supporting India's self-reliance and competitiveness on a global scale. The paper provides a roadmap for academics, policymakers, and business leaders to leverage IKS with AI, aiming for an innovative and resilient India by 2047.

Dr tatayya bommali

The aim of this study was to examine university students’ fear of success from the perspective of positive psychology. Two objectives were addressed: first, analyzing the relation between fear of success, optimism, self-esteem, self-efficacy, and search for meaning in life; second, exploring the variance of the fear of success, taking into account the affective dimension of the self (self-esteem) and search for meaning in life. The results confirmed that fear of success was positively related to search for meaning, and negatively to optimism, self-esteem, and self-efficacy. The variance of the fear of success was explained by the self-esteem and search for meaning in life. Implications for school psychologists were discussed.

Elena stănculescu

Background and Objectives: Pulmonary tuberculosis (PTB) remains a public health issue in Nigeria. The rapid diagnosis of PTB is essential for the early initiation of treatment and management of patients. The utility of the BACTEC MGIT 960 TB system was evaluated and compared with the Lowenstein Jensen (LJ) culture method for the recovery of Mycobacteria from sputum samples. Methods: A total of 2400 sputum samples submitted to the South East TB Zonal Reference Laboratory, Amachara Umuahia, Nigeria were tested. Samples were decontaminated using the standard N-Acetyl-L-Cysteine Sodium Hydroxide method and concentrated before processing. The processed samples were inoculated into both MGIT 960 tubes and LJ medium and incubated accordingly. Results: From all sputum samples, Mycobacteria were recovered from 201 (8.4%) sputum samples by the MGIT 960 system and 175 (7.3%) by LJ culture (p=0.014). The sensitivity for MGIT and LJ culture for mycobacteria were 95.0% and 80.1%, respectively. Among the 201 MGIT-positive cultures, 127 (63.2%) were identified as Mycobacterium tuberculosis complex and 74 (36.8%) as Mycobacteria other than tuberculosis (MOTT). The recovery rate of MTBC from LJ-positive samples was 84.0% and MOTT 16.0%. MGIT 960 identified more MOTT than LJ culture (p=0.045). The contamination rate associated with MGIT and LJ culture was 4.1% and 2.5%, respectively (p=0.037). The time to detection of mycobacteria in MGIT 960 and LJ was 14.8 days and 33.2 days, respectively. Conclusion: MGIT 960 has good diagnostic accuracy. It provided a more rapid and higher recovery of all mycobacteria than the LJ culture.

Karishma

With the expansion of human societies, extending up to almost every corner of the earth, transforming it to be as per their condition, humankind has proved their extraordinary dominance on the earth. The dominating attitude of humans has not resulted pleasantly every time. Poverty is one such curse that has shamed the progressing world community. Christianity has dedicated a large portion of its ministerial approach towards the underprivileged. This paper presents a missiological approach to uplift the slum dwellers in the city of Pune with education and health reforms. A similar project was experimented in 2014 among homeless people. The project did well and the results were significantly progressive and potential. It is assumed that this paper will bring an insightful approach that benefits the slums in Pune and enhance the “serving the humanity” aspect of the Christian mission.

Santosh kumar

We pose various congruences on the integers of form 6^n+1,n∈Z_+, which may encourage younger number theorists to research number theory and settle new dimensions in this field. We observed that there are only three prime numbers, namely 7,37, and 1297 of form 6^n+1,n∈Z_+, and no one Fermat numbers attains this form. Moreover, these integers end with 7, like Fermat numbers F_n,n≥2. Also, we discussed some congruences with number theoretic functions σ,φ and Möbious function μ.

Rajiv kumar

Aging seldom comes alone and it is considered to be the major factor for many diseases and comorbidities and disabilities. The objectives of the study are to examine demographic characteristics and prevalence of comorbidities and polypharmacy of elderly patients who were admitted at Sebha Medical Center according to the selected period. This study is descriptive and retrospective cross-sectional study conducted in Sebha during 2021. From 195 participants of the study, the highest rate of patients was from the age group of 65 - 74 years which accounted for 86 participants (44%) and followed by those age group of 75 - 84 years which was reported by 65 participants (33%). The majority of elderly patients have hypertension, (n = 116, 59%) and over one-third of the patients (n = 73, 37%) have diabetes mellitus while nearly one-quarter of patients have both diseases at the same time (n = 47, 24%). Nearly, three-quarters of patients have electrolytes imbalance (n = 142, 72%). Nearly, two-thirds of the patients had three to five comorbidity diseases (n = 122, 63%). Whereas, over one-third of the patients had just one or two comorbidities (n = 70, 36%). Almost all the participants have polypharmacy (n = 187, 96%). Just above half of the patients have five - ten medications (n = 100, 51%) compared with 45% of the patients from those who have more than ten medications (n = 87). This study showed that there is a strong relationship between the prevalence of polypharmacy and the number of comorbidities. A Spearman correlation test indicated that rate of comorbidities was related to polypharmacy with a significant correlation (P < 0.01). The present study found high prevalence of comorbidities and polypharmacy among elderly inpatients. Based on this high prevalence, practicing pharmaceutical care could play an effective role to reduce the risk of inappropriate polypharmacy among hospitalized elderly patients through encouraging clinical pharmacist to engage in clinical activities in hospitals.

Mediterranean journal of pharmacy and pharmaceutical sciences