Background: Preanalytical variability due to anticoagulant choice remains inadequately characterized in resource-limited tropical settings like Yemen, where environmental stressors exacerbate challenges. This study aimed to compare the stability and cost-effectiveness of K₂EDTA and K₃EDTA anticoagulants for complete blood count testing under simulated Yemeni conditions. Methods: Prospective more...
Background: Shilajit is a historically valued natural substance with promising but still preliminary scientific support for urinary and diabetic health, yet its growing popularity risks exploitation and exaggerated claims without rigorous human clinical validation. This study investigates the therapeutic effects of Yemeni Shilajit sourced from Dhamar, Ma’rib, and Raymah more...
Background: Cannabis sativa has garnered significant attention due to its complex phytochemistry and diverse pharmacological properties. Given the rising interest in medicinal cannabis, understanding its physicochemical properties is crucial for drug development, quality control, and abuse prevention. This study aimed to analyze its phytoconstituents, with a focus on the isolation more...
Background and Objectives: The Bayelsa Health Insurance Scheme (BHIS) is a state-designed social security plan in which enrollees benefit from a shared pool of cash based on premiums paid by participants. The study aimed to assess the self-reported effectiveness, service utilization, level of satisfaction, and barriers among beneficiaries, more...
Background: Epilepsy and cerebral palsy (CP) are reported as the two most common indications for electroencephalogram (EEG) requests in children in Nigeria. Although several studies have examined epilepsy and EEG findings in the country, most have not documented the conditions under which EEG recordings were performed—whether during wakefulness, natural more...
Background: Effective disinfection protocols are crucial in healthcare and pharmaceutical settings to mitigate infection and cross-contamination risks, especially with a growing immunocompromised population. Disinfectant efficacy varies, and understanding microbial resistance profiles is essential. This study aimed to evaluate the differential efficacy of ethanol (ET), isopropyl alcohol (IPA), and a more...
Background: Pioglitazone, a peroxisome proliferator-activated receptor gamma (PPARγ) agonist, has demonstrated potential in managing Alzheimer’s disease (AD); however, its oral administration is limited by systemic side effects such as cardiovascular risks and hepatotoxicity. This study aimed to formulate and evaluate a thermo-adhesive intranasal gel containing pioglitazone, utilizing more...
Background: Malaria in pregnancy (MiP) remains a critical public health concern in Nigeria, with significant implications for maternal and fetal health. Despite national policy guidelines advocating the use of Intermittent Preventive Treatment in pregnancy using Sulphadoxine- Pyrimethamine (IPTp-SP), its uptake remains suboptimal in many rural communities. This study aimed more...
Recently, the definition of cardiorenal syndrome (CRS), a condition with a complicated pathogenesis, has been revised. Logically, CRS syndrome should be classified according to the initial organ that is injured, resulting in damage to another organ. Hence, there are only three main categories of CRS. Category one includes acute and more...
Mucosal systems such as orally disintegrating films (ODFs) and mucoadhesive buccal films (MBFs) have gained attention and become a potential alternative to the conventional oral drug delivery systems, especially for patients who are geriatric or pediatric or those having difficulty in swallowing or drugs with extensive first-pass metabolism. Such more...
Patent foramen ovale (PFO) is a prevalent congenital cardiac anomaly. It is increasingly acknowledged as a significant factor in cryptogenic ischemic stroke, especially among young adults experiencing otherwise unexplained cerebrovascular incidents. This review summarizes recent advances in the epidemiology, pathophysiology, diagnostic strategies, and management of PFO-related stroke. The article more...
Background: Ward rounds are a cornerstone of inpatient care, critical to patient management, interdisciplinary communication, and bedside teaching. However, despite their importance, ward rounds are often unstructured and inconsistent, limiting both clinical efficiency and educational impact. Objective: This narrative review examines common deficiencies in current ward round practices and proposes more...
Dunbar syndrome (DS) is a rare condition, predominantly in females. It arises due to the compression of the celiac trunk and celiac plexus by the fibrous attachments of the median arcuate ligament of the diaphragm. DS mimics many common gastrointestinal disorders due to the postprandial nature of symptoms and is more...
Parkinson’s disease is the second most prevalent neurodegenerative disorder after Alzheimer’s disease. It is characterized by psychological disturbances and other symptoms that vary with the severity of the condition. Common mental health issues include anxiety, mood fluctuations, hallucinations, psychosis, depression, and cognitive decline. These psychiatric conditions should be more...
The exponential growth of biomedical literature presents both an unprecedented opportunity and a significant challenge for medical professionals and students. Conducting a thorough yet efficient literature review is a fundamental skill, essential for evidence-based practice (EBP), research, education, and scholarly writing. However, navigating this vast information landscape effectively remains more...
Purpose of review: This narrative review aims to assess the effectiveness of multimodal analgesia protocols (MAPs) in managing postoperative pain and reducing opioid consumption. The review evaluates the safety profile of MAPs, identifies the most effective components for different surgical contexts, and discusses their broader applicability in clinical practice. Given more...
Kidney mass lesions are common and are often discovered accidentally. Renal cell carcinoma (RCC) represents approximately 5% of all cancers. Men have a two-fold higher likelihood of developing the disease and experience a higher mortality rate than females. The differences between the genders are attributed to individual variations, including more...
Worldwide, cardiovascular diseases (CVDs) are the leading cause of mortality, demanding innovative therapeutic strategies. Nanomedicine offers promising solutions through nanoparticle-mediated drug delivery, enhancing precision, efficacy, and safety. This review examines nanocarriers, including liposomes, polymeric nanoparticles, and dendrimers, for targeted CVD treatment, encompassing coronary artery disease, atherosclerosis, and myocardial infarction. more...
Subcutaneous emphysema is defined as a trapped air in tissues under the skin. This entity most often occurs in the chest wall and neck but can infrequently happen in other parts of the body like the orbital area [1]. The main mechanism of subcutaneous emphysema is the traumatic damage of more...
Foreign bodies (FBs) in the scalp are a common incident following head trauma, especially in traffic accidents, and are detected in the early post-traumatic period. The persistence of these FBs may cause pain and paresthesia. We report a case of 41 years old man, whose victim it’s been more...