Cleome scaposa DC. has long been used in traditional herbal medicine for the treatment of pain and inflammation. The present investigation is an attempt to evaluate the antiemetic, analgesic and anti-inflammatory activities of Cleome scaposa leaves methanolic extract by using the chick emesis model (oral treatment), analgesia meter test (intraperitoneal treatment) in rats and carrageenan-induced rat paw oedema (oral treatment) respectively. The antiemetic activity (150 mg/kg b.w. of extract) was carried out by using chlorpromazine (150mg/kg) as a standard antiemetic drug. The analgesic activity (250 mg/kg b.w., of extract) was performed by using diclofenac sodium (50mg/kg) as a standard analgesic drug whereas, anti-inflammatory activity (500mg/kg b.w., of extract) was done and indomethacin (10mg/kg) was taken as a standard anti-inflammatory drug. The results showed significant antiemetic, analgesic and anti-inflammatory effects.

Dr. salman ahmed

Urolithiasis arises from disturbances in the urinary tract's physicochemical balance and hydrodynamic system. Medicinal plants have been known for millennia and are highly esteemed worldwide as a rich source of therapeutic agents for the prevention of various ailments. A comprehensive literature search of antiurolithiatic plants reported worldwide revealed the family Fabaceae with the highest number of cited species. The members, Macrotyloma uniflorum (Lam.) Verdc., Phaseolus lunatus Linn. and Phaseolus vulgaris Linn. have been selected and hidden versatile weapons of their seeds against urolithiasis such as analgesic, antioxidants, astringent, diuretic, emollient, high soluble oxalate contents, insoluble fibers, magnesium, potassium, phytic acid, pyridoxine (vitamin B6), have been discussed on a scientific basis to rationalize the folkloric use.

Dr. salman ahmed

Corona virus pandemic has swept a major section of the world population. In terms of infectivity it�s higher than any pandemic in the recent past. Corona virus, a member of the family Coronaviridae, spread from bat to human through an intermediate host pangolin. It has lower mortality rate than the previous pandemics in last 100 years such as Spanish Flu(1918-20),Asian Flu (1957-58), SARS Corona virus (SARS-Cov) (2003), H1N1 Swine Flu Pandemic(2009-10), Middle East Respiratory Syndrome (MERS) (2012), West African Ebola (2014-16) etc. Research shows Covid spike attaches ACE2 receptor; it leads to a release of cytokine into the blood capillaries near the alveoli and may ultimately turn into pneumonia. The alveoli get collapsed leading ARDF. The pulmonary inflammation proceeds to systemic inflammation that causes multiple organ failure. Drug like Chloroquine, Lopinavir/ritonavir, and Remdesivir may halt the spread of the virus in the body. Antipyretic is prescribed to reduce the temperature. This article comprises of detail mechanism of the dreadful disease along with its diagnosis and proposed treatment. This exploratory study mainly designed to generate awareness and provide information to the individuals who want to know the A to Z of Covid in nutshell. This article may create a pathway to number of upcoming scientific researches and may attract them to work on this field to enhance the probability of inventing appropriate vaccine and medicine to fight against this contagious disease and to win the battle against this Global Pandemic.

Dipa mitra

The objective of the paper is to predict corporate bankruptcy of selected telecom service sector companies. The study ranges for a period of ten years from 2006-2007 to 2015-2016 for three selected telecom service sector. By applying Altman's Z-score model the study analyze the financial position of the companies and suggests the financial components to be concentrated to improve the financial health. Further the study suggests that the companies should regularly estimate Z-score for making strategies to improve their financial position.

Dr. jeyalakshmi p

Natural products, the most significant source for pharmaceutical development, have been investigated and utilized to alleviate diseases since early human history. The currently accepted modern medicine from different natural products has gradually developed over the years and is God's gift in the sense of traditional knowledge. Trustful humanity believes that drugs can cure every ill of natural origin. Natural medicines, prevalent in holy books, folklores, Materia medica and other historical literature, have become an essential domain of modern pharmaceutical sciences. Natural compounds from terrestrial and marine organisms have been extensively used to treat many diseases in their natural form or as a template for synthetic modification. Several of these natural products have shown biological and pharmacological activities and serve as the starting point in the development of modern medicines. Screening of crude plant extracts opens the door to the discovery of novel bioactive compounds, and elucidation of their structures leads towards new synthetic preparations, which can be administered in reproducible, accurate doses for particular therapeutic purposes. However, what is needed are rapid screening techniques, structure-based design, bioactivity-safety evaluation, extraction and isolation, and clinical trials for drug development under innovations, which will share the profit of products derived from natural origin. The government sector, industries, and academic institutions also play an essential role in developing biological drugs for human health enhancement. This book comprises four chapters. The first chapter is related to urolithiasis. In this chapter, the types of urinary stone formation in humans, their mechanism, current antiurolithiatic strategies and their complications are discussed precisely and comprehensively. Chapter two declares urinary stone treatment in early civilisation. The third chapter is about globally used antiurolithiatic plants. This chapter is a treasure trove of information covering the importance of plants in combating urolithiasis, their diverse pharmacology, and a comprehensive list of 888 antiurolithiatic plants from 144 families used in 55 countries. The tabular format provides a clear understanding of their historical background, mechanism of action, therapeutic spectrum, and formulations with doses. Hopefully, this book will not only be helpful for the general public but also attract the scientific world to antiurolithiatic drug discovery. This valuable ethnopharmacological information will provide opportunities for the future research and development of new natural antiurolithiatic compounds. We extend our heartfelt gratitude to all the teachers, colleagues, and institutions whose unwavering support and encouragement made this book possible. We reserve a special thanks for the acquisition Editor of LAP Lambert Academic Publishing, Germany, whose inspiration and support were invaluable.

Dr. salman ahmed

The market for tertiary educational institutions, most especially for private universities, is highly competitive. The competitive nature of the market requires that Private Universities (PUs) step up their performance so as to remain competitive despite the major structural and market differences between them and public universities in the provision of tertiary education. The need for private universities to remain competitive in this turbulent market, calls for some careful examination of the factors that would enable private universities to enhance their performance. In this respect, this study sought to examine the effects of management competence, firm-level institutions, and human resource management (HRM) bundles on the performance of private universities in Ghana. Underpinned by the RBV and AMO theories, the study tested four hypotheses that sought to explain the relationships between the key variables of the study. The study was implemented using a quantitative research design. Out of the sixteen private universities sampled, thirteen private universities responded. The main research instrument was a structured questionnaire. Out of 230 questionnaires administered, 127 completed questionnaires were received and used for analysis. Collected data was analyzed using descriptive and inferential statistics (regression analysis) with the aid of SPSS software version 20 and AMOS version 23. Research findings from the tests of hypotheses established that management competence positively and significantly affected performance of private universities in Ghana. Though the study found that the composite variables of firm-level institutions and HRM bundles did not moderate the relationship between management competence and PU performance, the skills bundles (which is a component of the HRM bundles) significantly moderated the management competence – PU performance relationship in such a way that at high levels of skills bundle, management competence influences PU performance more than at low levels of skills bundle. Based on the findings of the study, it is recommended that PUs in Ghana institute competence acquisition and utilization policies, maintain appropriate firm-level institutions and HRM bundles and match these to their competence development strategies.

Cyril domeyelle dery

This paper attempts to review the status of law in the context of the UK. The critical areas reviewed in the study included the nature of the legal systems within the UK, focusing on the role played by law within the community and the sources of law. In the second task, the connection between law and the business world is established, trying to ascertain the role of company law, employment laws, the law of contract, and the intellectual property to the businesses. Task three assessed the existing laws regarding the different types of business organizations created in the country, concentrating on the legal requirements for establishing the same. The last task focused on the recommendation that the study makes in conclusion regarding the dispute resolution processes available in the current business world.

Zamzam abdelazim

Identity-based encryption (IBE) is a public key cryptosystem and eliminates the demands of public key infrastructure (PKI) and certificate administration in conventional public key settings. Because of the absence of PKI, the revocation drawback could be a crucial issue in IBE settings. Many rescindable IBE schemes are planned relating to this issue. Quite recently, by embedding associate outsourcing computation technique into IBE, Li et al. planned a rescindable IBE theme with a key-update cloud service supplier (KU-CSP). However, their theme has 2 shortcomings. One is that the computation and communication prices are above previous rescindable IBE schemes. The opposite disadvantage is lack of measurability within the sense that the KU-CSP should keep a secret worth for every user. Within the article, we have a tendency to propose a replacement rescindable IBE theme with a cloud revocation authority (CRA) to resolve the 2 shortcomings, namely, the performance is significantly improved and the CRA holds only a system secret for all the users. For security analysis, we demonstrate that the proposed scheme is semantically secure under the Decisional Bilinear Diffie-Hellman (DBDH) assumption. Finally, we have a tendency to extend the planned rescindable IBE theme to gift a CRA-aided authentication theme with period-limited privileges for managing an outsized range of varied cloud services.

Dr h shaheen

Dietary supplements are extensively consumed, but irrational use is a health hazard. Pharmacy students, being future healthcare providers, can facilitate rational use. The present study evaluated the knowledge, attitudes, and practices of pharmacy students at Srinivas College of Pharmacy, Mangalore, about dietary supplements and their role as an advocate, in addition to mental health correlations. 250 students selected through stratified random sampling took part in a cross-sectional mixed-methods study. A 30-question instrument (Cronbach's alpha=0.85) measured demographics, dietary supplement usage, knowledge, attitude, practices, and mental health was evaluated with the depression, anxiety, and stress Scale-21 (DASS-21). The data were collected during January-March 2025 and were analyzed with the chi-square test, logistic regression, and Pearson correlation tests. 35.0% (n=88) used dietary supplements regularly, with a preference for multivitamins (50%) and protein supplements (30%). Knowledge was moderate (60% risk aware), attitudes favorable (70% in favor of counseling), but practice restricted (25% informed peers). Everyday use of dietary supplements escalated stress probability (OR=2.5, 95% CI: 1.8-3.4, p<0.001), with correlation (r=0.38, p<0.01). In conclusion, students have promise as dietary supplement champions but require additional training to close knowledge-practice gaps and mitigate mental health risks. Curriculum and policy interventions are needed to enhance students' abilities in encouraging rational dietary supplement use and identifying potential mental health effects.

Mediterranean journal of pharmacy and pharmaceutical sciences

Kompetensi pedagogik merupakan kemampuan yang harus dimiliki guru dalam mengelola pembelajaran. Berkaitan dengan pengelolaan Pembelajaran Tematik fakta di sekolah menunjukkan banyak guru belum sepenuhnya mampu mengimplementasikan pembelajaran yang memiliki prinsip mengintegrasikan banyak materi. Untuk itu, penelitian ini bertujuan untuk mendeskripsikan kemampuan guru: 1) Memahami peserta didik dalam melaksanakan Pembelajaran Tematik di MI Miftahul Hidayah Tegalsari Tahun Pelajaran 2018/2019. 2) Merencanakan pembelajaran dalam melaksanakan Pembelajaran Tematik di MI Miftahul Hidayah Tegalsari Tahun Pelajaran 2018/2019. 3) Melaksanakan pembelajaran pada Pembelajaran Tematik di MI Miftahul Hidayah Tegalsari Tahun Pelajaran 2018/2019. 4) Mengevaluasi hasil belajar dalam melaksanakan Pembelajaran Tematik di MI Miftahul Hidayah Tegalsari Tahun Pelajaran 2018/2019. Hasil penelitian menunjukkan bahwa: 1) Kemampuan guru memahami peserta didik sudah sesuai indikator kompetensi pedagogik. 2) Kemampuan guru merencanakan pembelajaran sudah sesuai dengan indikator kompetensi pedagogik. 3) Kemampuan guru dalam melaksanakan pembelajaran ada satu indikator yang perlu diperbaiki. 4) Kemampuan dalam mengevaluasi hasil belajar sudah sesuai dengan indikator kompetensi pedagogik.

Educare: journal of primary education

Inflammation is a natural aspect of the immune system's response. Pain, redness, heat or warmth, and swelling are the four major symptoms of inflammation. Plants can generate a vast range of phytochemical substances as secondary metabolites, all of which have anti-inflammatory properties. Herbal medicines are significant cures for the treatment of a variety of disorders around the world. Medicinal plants are made up of roughly 7500 species, with representatives from about 17,000 higher flowering plant species. Even when synthetic chemistry has advanced beyond expectations, the utilization of natural products in the production of medications utilized in modern medicine is unrivalled. Anti-inflammatory medicines can help to reduce tissue damage and improve patient comfort by interfering with the pathophysiology of inflammation. As a result of the huge number of species available for investigation, the effective creation of new naturally occurring anti-inflammatory medications relies mostly on a multidisciplinary approach to finding new compounds. Despite the fact that many review articles have been written in this area, the vast majority of them only looked at the subject from a regional perspective. Various non-steroidal anti-inflammatory medicines have been proven to alleviate pain and inflammation by inhibiting the isoform of cyclooxygenase enzyme's digestion of arachidonic acid, hence lowering prostaglandin synthesis. Non-steroidal anti-inflammatory medicines come with a slew of negative side effects. Thus, there are, however, medicinal herbs that have anti-inflammatory therapeutic properties with a little or no negative side effects.

Mediterranean journal of pharmacy and pharmaceutical sciences

This chapter discusses the effects of stimuli that combine sexuality and aggression. It outlines the debate over aggressive versus nonaggressive pornography and discusses the frequency of aggressive pornography and bases for concern. Aggressive pornography and sexual arousal is explored in the chapter wherein initial findings, victim's responses, individual differences, context of assessment, and conclusions are discussed. The chapter reviews the effects of aggressive pornography on responses other than aggression wherein it has discussed about changes in sexual responsiveness, fantasies, and perceptions and attitudes. The effects of aggressive pornography on aggression are explored in the chapter wherein research findings are discussed in detail and summary of effects on aggression, theoretical analyses, and the construct validity of assessing aggression are also described. The data across the laboratory and field experiments discussed in this chapter raise a variety of theoretical and empirical issues that should be addressed in future research. Particularly noteworthy are questions concerning stimuli, subject, and setting characteristics.

John dolores

This journal article investigates the evolving landscape of healthcare monitoring systems empowered by Artificial Intelligence (AI). Through an in-depth analysis of recent developments, methodologies, and case studies, the article elucidates the pivotal role of AI in revolutionizing patient care, diagnostics, and overall clinical outcomes.

Dhruvitkumar talati

This comparative study was conducted between local (Libyan) and imported (Chinese) garlic to evaluate their antibacterial activity against some isolated gram-positive and gram-negative bacteria. The study was carried out by using the agar well diffusion method at different aqueous extract concentrations (25%, 50%, 75% and 100%). The results showed that distinct antibacterial effects on both types of garlic with some differences between local and imported garlic. However, the zone of inhibition was more against Staphylococcus aureus, Klebsiella pneumonia and Escherichia coli, respectively. Furthermore, the antibacterial activity increased with the increase of concentration. So, this study recommends that garlic should be used against bacterial infection and more studies may be done against other bacterial species, especially multidrug-resistance strains.

Mediterranean journal of pharmacy and pharmaceutical sciences

Use of chemical fungicide to control plant diseases causes several adverse effects such as, development of resistance in the pathogen, residual toxicity, pollution to the environment etc. So an alternative way to overcome the usage of dreadful chemicals is very important. The use of plant extracts as biofungicide is one of the popular and effective method. Araucaria columnaris is a commonly seen ornamental plant known as Christmas tree. It’s a South African species, under the family Araucariaceae. Hence, in the present study, the plant resin extract was tested in-vitro against major plant pathogensby preliminary bioassay. It was found that up to 95% reduction of mycelium growth was observed against major phytopathogens such as Fusarium oxysporyum, Rhizoctoniasp, Cylindrocladiumsp, Alternariasp, and Colletrotricum sp., causing tomato wilt, damping off, foliage blight, and leaf blight diseases in economically important plants. Up to our knowledge it is the first report showing the antifungal activity of Araucaria columnaris resin as antifungal agent. By using this valuable tree, further work will be done to formulate commercial biofungicide.

Dr. saranya devi k

This paper centers around how innovations adds to enhancing interoperability between IoT gadgets, and making effectively utilization of IoT gadgets. The proposed stage innovation gives semantic-based IoT data administrations, and semantic interoperability of IoT gadgets. This administration stage can be material to a great deal of semantic IoT administrations: gathering imperceptible data in genuine condition by brilliant gadgets, giving keen life benefits by sharing, taking an interest, circulating open detecting data.

Dr h shaheen

The aim of this work was to prepare chitosan nanoparticles loaded with antineoplastic drug Lomustine (LCNPs), by ionic-gelation method with homogenization. The nanoparticles were characterized for particle size, polydispersity index (PDI), surface morphology, encapsulation efficiency, in-vitro drug release and cytotoxicity on human lung cancer cell line L132 by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. The particle size, zeta potential and encapsulation efficiency of prepared nanoparticles ranged from 75±1.1 to 637±1.6 nm (PDI from 0.05±0.001 to 0.18±0.007), 37.2±0.21 to 53.8±0.18 mV and 66.74±1.4 to 98.0±1.8% re- spectively. The particles were spherical in shape with smooth surface in scanning electron microscopy (SEM) and transmission electron microscopy (TEM) images. Mechanical shearing by homogenization treatment significantly changed the nanoparticle size. The drug release rate was biphasic and diffusion controlled over the 8 h. LCNPs greatly inhibited the growth of the L132 cancer cell line used in this study in comparison to the native Lomustine (LMT).

Archana mehrotra

In their different ownership structures, business enterprises pursue different strategies towards accomplishing their owners’ needs and interests. At the heart of these accomplishments is the generation of sufficient financial returns to cover obligations as they become due and residual incomes for the owners. It is doubtless that without a grip of financial stability, the survivability of for-profit organizations becomes bleak. Financial management plays and instrumental role in this case. The generation of sufficient information for decision making for the business and investors alike is integrally critical in shaping the progression of the business enterprise. While businesses provide financial statements according to prevailing laws and accounting standards to the public for their consumption in decision making, they are further needed to be accountable to them regarding their performance and investors’ engagements, especially considering that investors are foundational sources of capital for organizational operations.

Zamzam abdelazim

To improve education quality and governance, the Higher Education Commission of India (HECI) has proposed four regulatory entities, including the National Accreditation Council (NAC). To build up India as a universal knowledge giant over the next ten years, the policy promotes equitable educational opportunities and transformative initiatives. To significantly improve the standards for higher education in India, quality control, accreditation, & ranking systems become crucial. With an emphasis on quality, employability, and lifelong learning, the National Education Policy-2020 (NEP-2020) seeks to create a flexible, value-based educational system that integrates 21st-century capabilities. India's higher education is currently at a critical juncture, requiring transformation to enhance its overall contribution to society and address social injustices. This involves examining how information is produced and how students are taught to promote sustainability and social responsibility. Higher education institutions must comprehend and address student expectations regarding quality because the service sector is expanding quickly due to liberalization, privatization, and globalization. As a result, evaluating service quality becomes crucial for future enhancements and feedback. The Higher Education Commission of India (HECI) legislation, 2018, was introduced by the Ministry of Human Resource Development toward the end of June with the goal of repealing the University Grants Commission (UGC) Act, 1956, which has been in place for seven decades. The HECI will interchange with the University Grants Commission (UGC), which has been the foundation of India's college and university structure. This transition analyzes the proposed bill and examines its shortcomings. This advocates that the current bill be unsuccessful in reporting the flaws of the previous official; instead, it merely reflects those issues and will not resolve the long-standing problems of low autonomy and subpar instruction in the higher education system. As the new regulator, HECI's strategy isn't very revolutionary. Regulators who encourage centralization of duties to reduce autonomy must be disregarded at moments when Indian institutions are striving to rank highly in the world.

Dr. awadhesh singh gautam

Critical race theory (CRT) is an intellectual movement that seeks to understand how white supremacy as a legal, cultural, and political condition is reproduced and maintained, primarily in the US context. While CRT is part of a much longer research tradition investigating race and racism, which includes such key fgures as W. E. B. Du Bois, Frantz Fanon, Angela Davis, Audre Lorde, Gloria Anzaldúa, Cherríe Moraga, and many more, CRT distinguishes itself as an approach that originated within legal studies (in part building from and responding to critical legal studies); aims to be a vehicle for social and political change; has been adopted interdisciplinarily across many fields, including perhaps most notably education; and, in certain contexts, has come to be the umbrella term for studies of race and racism generally. CRT originated as an extension and critique of critical legal studies (CLS). It was also an outgrowth of Marxist critical theory that challenged the rationality, impartiality, and purpose of the legal system. According to the tenets of both CRT and CLS, the legal system is a political and ideological institution that, in part, rationalizes and justifies the existence of the state. Te legal system also requires mastery of an arcane and intentionally inaccessible vocabulary and a set of knowledge and power processes that limit ordinary people’s access to it. Te arbiters of law pretend to rely on reason but actually rely on subjective, politically motivated, culturally biased, and quasi-religious rationale for making and enforcing their decisions. CRT maintains the critique of legalistic thinking found in critical legal studies, but then adds a framework for understanding white supremacy as an immutable fact of a neocolonial state, as well as a praxis for changing it. What separates CRT from other forms of racial critique is that, “Unlike most of the earlier genres of race cholarship, critical race scholarship does not treat race as an independent variable; rather, it regards race as a site of struggle” (Orbe & Allen, 2008, p. 209).

Kamal singh