Ethanol extracts of leaves, male flowers and fruit peel of Luffa cylindrica (L.) Roem., were evaluated for analgesic effect using the analgesy meter test, a mechanically induced pain model. Extracts at 500 mg/kg, p.o., were tested and compared with diclofenac sodium 50mg/kg as a standard analgesic drug. The mechanical force was applied to the rat's paw and continuously increased. The point at which the rat can’t bear further pressure and starts to struggle to free the paw was taken as a nociceptive response. Readings were taken before and after 1, 2 and 3hr following drug administration. The analgesic response was continuously increasing till 3hrs. Tested extracts produced significant and comparable analgesic effects as with diclofenac sodium.

Dr. salman ahmed

Pharmacists are expected to play major roles as members of diverse perioperative care teams besides implementing medication safety standards, pharmacist’s roles include optimizing drug therapy and other clinical interventions. Yet, developing general perioperative management as another crucial role operation room, pharmacists play and incorporating it into pharmaceutical education would be important. Enriching perioperative care provided by pharmacists can contribute toward improving the clinical competence of these professionals. Presently, there are no pharmacists in Zawia who participate in perioperative care. The objective of this study was to assess the pharmacist's knowledge of general anesthesia and drugs used to anesthetize patients who suffer from hypertension. A cross-sectional study was conducted in Zawia City, Tripoli in 2023. A self-designed questionnaire was distributed to 100 pharmacists. The study found that more than half of the pharmacists have humble knowledge about the drugs used in anesthesia, the findings indicated weakness in their information about drugs used to manage hypertension in surgery, and 36.0% know that sodium nitroprusside is used to control blood pressure during the operation. In conclusion, this study reported that some of the study's pharmacist participants had weak points that contributed to a high percentage of incorrect knowledge. These weak points may be attributable to poor educational preparation or a lack of training before the pharmacists began working in hospitals.

Mediterranean journal of pharmacy and pharmaceutical sciences

In an era of rapid technological advancement, the digital divide between rural and urban communities has become increasingly apparent. This study aims to investigate consumer awareness towards cyber security in both rural and urban settings, recognizing its critical importance in safeguarding personal and sensitive information. The study underscores the urgent need for targeted interventions to bridge the digital divide in cyber security awareness. Policymakers, educators, and community leaders must collaborate to implement initiatives tailored to the unique needs of rural populations, including improving access to technology, enhancing digital literacy programs, and fostering a culture of cyber security consciousness. By addressing these disparities, we can strive towards a more inclusive and resilient digital society where all individuals, regardless of their geographic location, are empowered to navigate the digital landscape securely. This research paper delves into the awareness and attitudes of consumers regarding cyber security in both rural and urban settings. With the increasing prevalence of online activities, particularly e-commerce, understanding the level of awareness and concerns about cyber security is crucial. The study analyzes data collected from 100 respondents, examining demographics, online shopping behavior, encounters with security issues, familiarity with safety measures, and sources of information about cyber security. The findings provide insights into the digital divide between rural and urban communities and offer recommendations for enhancing cyber security awareness and education.

Dr. kishor bholane

Natural products, the most significant source for pharmaceutical development, have been investigated and utilized to alleviate diseases since early human history. The currently accepted modern medicine from different natural products has gradually developed over the years and is God's gift in the sense of traditional knowledge. Trustful humanity believes that drugs can cure every ill of natural origin. Natural medicines, prevalent in holy books, folklores, Materia medica and other historical literature, have become an essential domain of modern pharmaceutical sciences. Natural compounds from terrestrial and marine organisms have been extensively used to treat many diseases in their natural form or as a template for synthetic modification. Several of these natural products have shown biological and pharmacological activities and serve as the starting point in the development of modern medicines. Screening of crude plant extracts opens the door to the discovery of novel bioactive compounds, and elucidation of their structures leads towards new synthetic preparations, which can be administered in reproducible, accurate doses for particular therapeutic purposes. However, what is needed are rapid screening techniques, structure-based design, bioactivity-safety evaluation, extraction and isolation, and clinical trials for drug development under innovations, which will share the profit of products derived from natural origin. The government sector, industries, and academic institutions also play an essential role in developing biological drugs for human health enhancement. This book comprises four chapters. The first chapter is related to urolithiasis. In this chapter, the types of urinary stone formation in humans, their mechanism, current antiurolithiatic strategies and their complications are discussed precisely and comprehensively. Chapter two declares urinary stone treatment in early civilisation. The third chapter is about globally used antiurolithiatic plants. This chapter is a treasure trove of information covering the importance of plants in combating urolithiasis, their diverse pharmacology, and a comprehensive list of 888 antiurolithiatic plants from 144 families used in 55 countries. The tabular format provides a clear understanding of their historical background, mechanism of action, therapeutic spectrum, and formulations with doses. Hopefully, this book will not only be helpful for the general public but also attract the scientific world to antiurolithiatic drug discovery. This valuable ethnopharmacological information will provide opportunities for the future research and development of new natural antiurolithiatic compounds. We extend our heartfelt gratitude to all the teachers, colleagues, and institutions whose unwavering support and encouragement made this book possible. We reserve a special thanks for the acquisition Editor of LAP Lambert Academic Publishing, Germany, whose inspiration and support were invaluable.

Dr. salman ahmed

In today’s ever-changing world with new advancements, Customer Experience or CX plays a critical role in a value proposition, thereby affecting customer loyalty, top-line metrics and business growth. Artificial Intelligence (AI) is becoming very important because AI provides adequate, rapid, and smooth Mass-Customized interactions. Self-checkout to virtual assistants, current innovation reveals how tools supported by Artificial Intelligence increase customer-centric experience, helping to decipher and estimate the customer’s wants and needs in real-time. Thus, this paper focuses on the revolutionary impact of AI in recasting customer experience management initiatives, which includes understanding AI applications in customer marketing, customer service, customer emotion analysis, and prediction of the probable behavior of customers. By means of AI, organizations can design and deliver unique experiences for their customers, fine-tune contacts, and improve satisfaction, loyalty, and customer retention. This article thus presents a critical discussion of prior and current literature on AI and customer experience and the research methodology adopted for assessing AI quality in improving CX innovations. It expounds on results from recent case studies on the value of integrating AI. It is not a matter of whether customer experience will be powered by AI, but when and by how much, as customer data drives decisions, interactions with customers, and learning in near-real time. Therefore, as AI technologies advance, companies adopting AI in customer experience approaches will close distance or gain ground on their competitors since they will efficiently offer superior, preemptive and personalized experiences.

Mohan krishna mannava

In Libya, mothers commonly use natural products for their infants. The purpose of this survey was to evaluate the level of awareness of mothers using natural products for their infants, a validated questionnaire-based survey was distributed for mothers in several hospitals, the selected random group included 152 mothers of infants aged from day one birth to one year old, an analysis of the data revealed that 68% of mothers were using natural products and the most predominant age was between 20 - 30 years, 63% were living in Tripoli and 52% were undergraduate level of education. Further statistical analysis was revealed a significant difference for measuring the degree of awareness of all the natural products combined together (p = 0.001) and a similar degree of significant difference to the degree of awareness of each natural product alone (p = 0.001). A correlation coefficient test by Spearman was preformed to evaluate if there is any association between participants’ demographic data and the question which measures the level of mothers’ awareness. The results showed that mothers have no awareness on how to use these natural products and no correlation between the participants’ demographic data and the way the mothers use these natural products, except between the fennel and the education level (p = 0.033, p < 0.05, respectively). In conclusion, mothers have no awareness on how to use natural products, an appropriate attention by health care providers should be given to nursing mothers for herbal use.

Mediterranean journal of pharmacy and pharmaceutical sciences

The learning process in the new normal is currently still undergoing a process of adaptation. Where the learning is still limited face-to-face and some others are brave. Process adaptation. This learning requires an NHT learning technique that makes it easier for class II students to understand the concept of social studies learning in the natural and artificial environment as a whole and is able to increase their motivation in learning. The research method uses a quantitative design using a non-equivalent control group design. The variables of this study consisted of independent variables and dependent variables. The population of this study were all second grade students at Anak Saleh Elementary School, while the samples were second grade students who carried out the bold learning process and second grade students who carried out offline learning processes. The data collection used in this study included interviews, questionnaires and observations. The data analysis technique is validity test and reliability test. Analysis of the data used through data coding, data transfer to a computer using prerequisite tests and hypothesis testing. The results of the research show: 1) the level of understanding of the social studies concept of class II students who study with the Numbered Head Together (NHT) learning technique is better than conventional learning techniques of 0.429 (results from the t-test) and 2) the level of motivation to learn social studies of class students II with Numbered Head Together (NHT) learning technique of 0.733 is better than conventional learning which is only 0.704. Surely this is greater than rtable = 0.361.

Educare: journal of primary education

Shell and tube heat exchanger is the most common type of heat exchanger, widely used in oil refinery and other large chemical process. The energy present in the exit stream of many energy conversion devices such as I. C engines, Gas turbines etc. goes as waste, if not utilized properly. For example, the heat energy stored in the engine coolant can be utilized in a better way by recovering the heat for heating purposes inside the cabin. It is comparatively economical than the existing heating arrangements, which employ conventional heating coils. So, the present work has been carried out with a view to predicting the performance of a shell and tube heat exchanger in the field of waste heat recovery application. The objective of this project is to design a shell and tube heat exchanger and study the flow and temperature field inside the shell and tubes using ANSYS Fluent R14.5. An attempt has been made to calculate the performance of the above heat exchanger with and without baffles for parallel flow configurations, and the results so obtained have been compared.

Boopathy govindarajan

India's hotel and hospitality industry occupancy decreased significantly in the first quarter of 2020, as the outbreak of COVID-19 affects different segments of the market. The outbreak of the novel coronavirus (COVID-19) has inflicted a blow on industries around the world, but maybe none as devastating as hospitality and travel. Depending on the length of the pandemic, companies across the industry adjusted growth forecasts for 2020, estimated profits to be conservatively 40-50 percent lower than expected before the outbreak. The effect on hospitality demand is greater than many other sectors, but even among hotels, air and cruise ships, and restaurants it is varied. Hotels and airlines operate at half capacity, with both business and leisure travelers canceling scheduled trips and not arranging any for the near future.The present article aims to study some novel practices for the survival of hospitality industries once the lockdown is over.

Ketan chande

Several studies demonstrate a strong correlation between talent and organizational performance. This view has led to continued improvement of methodologies, human resource scorecards, benchmarking, and engaging in best practices aimed at attracting both talent and better business management. As all these underline advancements of organizational strategic goals, it also determines the development and alignment of individual performance (Savanevičienė and Vilčiauskaitė, 2017, pg. 247). Although most of the studies involve for-profit corporations incorporating them in various industries proves to be both logical and psychologically sound. Regarding this project, the major focus is on determining talent strategies that best companies use to attract and retain people. For the project, Deloitte has been chosen as the reference organization for the strategies it uses and how its human resource management has been able to sustain attracting and retaining good talent.

Zamzam abdelazim

Purpose: The study aims to explore all possible morphological features of calcium oxalate monohydrate and calcium oxalate dihydrate crystals and their habits in case of inhibition. Methods: The study was carried out on a glass slide to observe the growth and inhibition of calcium oxalate monohydrate (COM) crystals by using infusions (5-20%) of Macrotyloma uniflorum (Lam.) Verdc, Phaseolus lunatus Linn. and Phaseolus vulgaris Linn. The reagents of the double diffusion gel technique were used for this purpose. Results: Calcium oxalate crystals are divided into three types: calcium oxalate monohydrate, dihydrate, and trihydrate. These types are further divided into sub-types based on their morphology. In the case of calcium oxalate monohydrate (COM), these crystals are donuts, dumbbells, needles, platy, prismatic, rosette, round edges and X-shaped. Calcium oxalate dihydrate (COD) is the elongated large rods and tetragonal bipyramidal forms. In the present study, dendritic or arborescent (tree-like platy crystals) were observed for the first time as part of a COM growth. Long chain loose agglomerates and compact aggregated crystals are the typical pattern of calcium oxalate crystals. All tested infusions caused growth inhibition of calcium oxalate crystals. Smaller nucleation zones and defective shapes of the grown crystals are declared different growth inhibition patterns. Conclusion: This study gives extensive information about morphology, aggregation and growth inhibition of calcium oxalate crystals.

Dr. salman ahmed

Les études sur la langue française la présente souvent dans des situations où elle est en contact avec les langues africaines. Elle co-apparait avec les langues africaines dans les discours romanesques. Cette co-apparition n’est pas sans conséquences pour les deux langues en contact. Certains linguistes, surtout les sociolinguistes et les didacticiens, parlent d’insécurité linguistique. Ils la lient à toutes les situations linguistiques où deux langues entrent en contact. Ngamassu (2007, p.94) dit dans ce sens que « toute situation de contact des langues est source d’insécurité linguistique, car aucun locuteur/scripteur ne peut maîtriser toutes les variétés ou niveaux d’une langue ». Cette affirmation restreint l’insécurité au locuteur ou au scripteur. Les linguistes ignorent souvent l’impact négatif du contact des langues et s’intéressent à ses conséquences positives. Cet article a porté sur les manifestations de l’insécurité linguistique dans la prose romanesque de Kourouma et Badaman. Il a permis de voir que l’usage des langues maternelles dans le français constituait une menace de disparition et d’abâtardissement de la langue française.

Assanvo

Vitamin D is a hormone which plays a vital role in immune response regulation, including the prevention of inflammation and autoimmunity. Insufficient vitamin D may increase the risk of infection. Vitamin D deficiency is not the only factor linked to an elevated risk of COVID-19 infection. Recent studies have discovered a link between SARS-COV-2 infection risk and blood type. This study was aimed to examine the association of vitamin D and blood groups with the severity of COVID-19. A retrospective study was conducted on 224 confirmed COVID-19 patients, aged between 18 and 89 years old. Patients were divided into three groups (asymptomatic, moderate, and severe cases), and serum 25(OH)D concentration and blood group were analyzed for all the patients. Data of the severe cases were obtained from Souq Althalath Isolation Center, Tripoli, Libya, while moderate and asymptomatic cases were obtained from Abushusha Polyclinic and Aldahmani COVID Filtration Center, during 22nd February 2021 and 28th April 2021 and serum 25(OH)D concentration and blood group were statistically analyzed for all the patients. The percentages of males and females were found to be 47.3% and 52.7%, respectively. Disease severity was distributed as follows: 12.5% asymptomatic, 44.6 % moderate and 42.9% severe. Most of the severe cases had vitamin D deficiency (88.5%). Among the severely ill patients, 39.6% had blood group A and 09.4% had group O, while 22.9%, and 28.1% had blood group B and AB, respectively. In contrast, among the asymptomatic patients, only 7.1% had group A and 85.7% had group O. Overall, the difference in the distribution pattern of blood group in the three severity categories was highly significant (p < 0.001). The prevalence of Rh positivity among asymptomatic, moderate and severe cases was 78.6%, 76.0%, and 60.4%, respectively. This study concludes that insufficient vitamin D levels might influence the severity of COVID-19. COVID-19 patients with blood group A and those who are Rh-positive could be more vulnerable to developing COVID-19 severity.

Mediterranean journal of pharmacy and pharmaceutical sciences

An attempt was made for screening of salt tolerant against sodium chloride (NaCl) salt and growth promotion efficacy of eight different phosphate solubilizing bacterial (PSB) isolates under in vitro conditions. An efficient isolate which exhibited maximum phosphate solubilization, salt tolerant, Indole-3-Acetic Acid (IAA) production and root colonization potential in maximum concentration of NaCl (7%) was identified as Bacillus cereus based on 16S rRNA sequencing. It was recorded that highest phosphate solubilization in 7% NaCl concentration (70% and 374 μg/mL) in agar plate and broth assay respectively. IAA production was observed to be decreased when salt concentration increases, the isolate showed significant amount of IAA in normal culture media without amendment of NaCl (74.94 μg/mL) and at 7% gradual decrease of IAA production was observed (30 μg/mL). Maximum colonization of isolate in the roots of Zea mays was also observed in the study.

Dr. saranya devi k

This chapter discusses the effects of stimuli that combine sexuality and aggression. It outlines the debate over aggressive versus nonaggressive pornography and discusses the frequency of aggressive pornography and bases for concern. Aggressive pornography and sexual arousal is explored in the chapter wherein initial findings, victim's responses, individual differences, context of assessment, and conclusions are discussed. The chapter reviews the effects of aggressive pornography on responses other than aggression wherein it has discussed about changes in sexual responsiveness, fantasies, and perceptions and attitudes. The effects of aggressive pornography on aggression are explored in the chapter wherein research findings are discussed in detail and summary of effects on aggression, theoretical analyses, and the construct validity of assessing aggression are also described. The data across the laboratory and field experiments discussed in this chapter raise a variety of theoretical and empirical issues that should be addressed in future research. Particularly noteworthy are questions concerning stimuli, subject, and setting characteristics.

John dolores

This study was carried out to verify all the manual process involved in generating Students Examination Result and to seek a way of automating the system for effective operations. Computer and its appreciations have become vital tools in the economic, industrial and social development of advanced countries of the world. Most educational institutions in Nigeria, such as Universities, Polytechnics and Colleges of Education still operate on the manual method of record keeping and computation of students’ grade point averages (GPA) which is time-consuming and error-prone especially when the number of students is large. This paper examines the inadequacies involved in the manual method of calculating Students CGPA (cumulative grade point average) and proposes a solution by developing a software application to facilitate the automated processing of the results. The software was developed using the Microsoft Excel spreadsheet program. The developed software was tested and found to performed well and produced expected results on completion. With it, it was possible to compute Grade Point Average (GPA) and Cumulative Grade Point Average (CGPA) for each student based on examination scores entered. The new system has some qualities such as reduction in the cost of processing of information, reduction in time spent in computing GPA and generating transcripts, increase in accuracy and efficiency, and elimination of duplication of effort which makes it superior to the manual system of student record keeping. This new system is flexible and can be modified to suit any kind of student’s record-keeping and data processing.

Ogala justin onyarin

The main purpose of the research is to develop modern tools for insurance management in the global economic crisis, to make an objective assessment based on a critical analysis of existing ones, to identify situations that could lead to international economic, social and natural threats. It is made some recommendations for the development of insurance calculations for the republic of Uzbekistan. Methods: Methods for reforming modern calculation of insurance tariff are recommended by means of theories of probabilities, statistical and mathematical analysis, and foreign advanced countries practical types of summarizing. Findings: While making an analysis, it has found that modern tools for the insurance management of Uzbekistan are needed. We proved this by the results of the modern calculation of insurance in tables (1-6). For the development of the insurance market of Uzbekistan, it should be analyzed by means of penetration and density of insurance premiums, making the deepest calculation of risks of the economy of Uzbekistan, and using the main principals and formulas of the theory of probability. Conclusions: In the end, we can take some results, and give some recommendations such as using the tools of theories of probabilities can help us find the main risks of economy, its powers of influences of the market economy, statistical and mathematical analysis also add some practical, objective results for making under control of any types of insurance risks.

Ikboljon odashev mashrabjonovich

Background: To assess the awareness, knowledge about refractive errors and strabismus among the general public in southern Indian states of Andhra Pradesh and Telangana. Methods: A cross sectional population-based survey used a semi structured questionnaire on awareness, knowledge on refractive errors and strabismus done as part of knowledge, attitude and practices study (KAP). Stratified multistage cluster random sampling method was used with a sample size of 867 adults- ≥16 years. Having heard of refractive error and strabismus was defined as awareness and having knowledge of the type of error for which spectacles were worn, was considered as knowledge. A pilot study was conducted to validate the questions used in the main study. Statistical package SPSS (version 19) was used for analysis to calculate logistic regression and odds ratios for gender, age, education and urban-rural areas. Results: A total of 782/867 (90.1%) subjects participated in the survey with females 47.4%. 581 subjects (74.3%) were aware of refractive error. 690 subjects (88.2%) were aware of squint. With multiple logistic regression about awareness of refractive error to various variables, subjects who were educated 11th class to degree had a higher awareness (OR: 2.40; CI: 1.25-4.60). With multiple logistic regression about awareness of squint to various variables, females had a higher awareness of squint (OR: 1.98; CI: 1.19-3.31). Conclusions: Awareness of squint and refractive error was high among the general public, but the knowledge of it was limited.

Srinivasa reddy pallerla

Among the consequences of armed conflict, the effect on the mental health of the civilian population is one of the most significant aspect of psychiatric disorders. Studies of the general population show a positive increase in the incidence and prevalence of mental disorders. This study is aimed to determine the relationship of the national crisis on the mental health conditions of university students and their academic performance. Specifically, this study was aimed to evaluate the national crisis effects on the mental health and the academic performance as well as the association of the national crisis, mental health and academic performance. 40 sample size of pharmacy students at the academic year 2019-2020 at Attahadi University, Tripoli, Libya were used in this study and a survey of validated questionare for mental health was considered. The findings revealed that the effects of national crisis on the mental health of the students disclosed the verbal interpretation of rarely grade. Indeed it can be found that mental health of the students was not of greatly affected in this sample. The academic performance of the students disclosed that academic year levels one and three have verbal interpretation of good and academic year level two has fair. Though the academic performance of the students did not show a verbal interpretation of weak or very weak. It is still worthwhile to note that none of them has reached the very good and the excellent performance. It can be concluded that a need for the students coping strategies be enhanced for them to reach their maximum potential with their academic performance. This study shows also that a weak positive relationship among the variables. Though it’s not that high, indeed, the mental health of the students can be a predictor to their academic performance.

Mediterranean journal of pharmacy and pharmaceutical sciences

Pelvic inϑlammatory disease (Waram al-Rahim)is one of the most serious gynaecological infections of the upper female genital tract with the worldwide annual rate of 10-20/1000 women of reproductive age. The objective planned for the study was to evaluate the effect of Sharbat-e-Deenar in uncomplicated Pelvic Inϑlammatory Disease (uPID). A pre and post observational single group clinical study was carried out in the Department of IlmulQabalatwaAmrazeNiswan, National Institute of Unani Medicine, Hospital, Bengaluru. Diagnosed cases (n=30) of uPID were included in the study. Patients with complicated PID, history of antibiotic therapy within seven days of recruitment; delivery, abortion or gynecologic surgery within the last 30 days, systemic diseases, malignancies, pregnancy & lactation were excluded. Sharbate-Deenarconsists of Poste baikhekasniandTukhmekasni(Cichorium intybus Linn.), Gulesurkh (Rosa damascene mill.), Tukhmekasoos(Cuscutare৒lexaRoxb.) and Rewandchini (Rheum emodiWall. ex Meissn) were administered orally in a dose of 20 ml twice daily for 14 days. Outcome measures were 30-70% clinical improvement in Visual Analogue Scale (VAS) score for lower abdominal pain and McCormack Pain Scale (McPS) score for abdominopelvic tenderness and White Blood Cells (WBCs) count <10 on saline microscopy of discharge. Data were analyzed using paired Student ‘t’ test, Wilcoxon Signed rank test and Paired Proportion test.Clinical improvement of 30-70% in McPS and VAS score was achieved in 96.7% (p<0.001**) and 93.3% (p<0.001**) patients respectively. WBCs count <10 on saline microscopy of discharge was achieved in 70% patients (p<0.001**).Sharbat-e-Deenarwas effective in improving the sign & symptoms of PID due to its anti-microbial, anti-inϑlammatory, antispasmodic and anti-oxidant properties. No adverse effect of the research drug was encountered during the study. Hence, Sharbat-e-Deenar serves as an effective alternative in patients with PID, proving the research hypothesis.

Dr ismath shameem