Monosodium urate monohydrate crystals are deposited in peripheral joints, causing gout and eliciting an intense localized inflammatory attack. In contrast, collecting ducts and medullary interstitium is a urinary calculus, which causes dysuria, nausea and hematuria. The purpose of the present study is to observe possible growth patterns of monosodium urate monohydrate crystals. The crystals were grown in test tubes using a single diffusion gel technique and were observed on the 7th,14th, 21st, 28th, and 40th days. Needle and spherulite-type crystals were observed on the 14th day, while arboresque, crystal sheaves, densely branched, dumbbell, mushroom-type spherulites, plumose and hexagonal prismatic crystals were observed for the first time. After the 40th day, complete spherulites were observed with their aggregates. The crystals were characterized by Scanning Electron Microscopy, Energy-Dispersive X-ray and Fourier Transform infrared spectroscopies. The pattern of MSUM will help determine the role of different natural products in the modulation, inhibition or promotion of these crystals by affecting the shape, size, transparency, approximate number and total mass of growing crystals. In case of inhibition or modulation, it will help evaluate prophylactic management. In contrast, the promotion of the crystal will give an idea about the risk factors of gout and kidney stones.

Dr. salman ahmed

The study aimed to determine the effectiveness of gamifying instruction in the English language proficiency of Grade 8 Filipino ESL students in one University in Bicol, Philippines, that offers Junior High School. The quasi-experimental single pretest-posttest design was used in the study. The researcher-made test which underwent series of validation was given before and after the intervention period to determine the level of English proficiency and level of effectiveness of the games. Statistical treatment was done employing frequency count, T-test and Analysis of Variance (ANOVA). The findings revealed that there was significant difference between the pretest and posttest of the respondents using gamification. Thus, it can be inferred that the games helped in improving the level of English proficiency of the Grade 8 students. The statistical test results disclosed further that the effectiveness of the three games introduced to the students were significantly high. With these findings, it was recommended that language teachers should use gamification as supplementary instructional material in improving the English proficiency of the students.

Darrel ocampo

The study was conducted on glass slides to observe the growth patterns of urinary calcium oxalate monohydrate crystals and their inhibition using 5, 10 and 15% Phaseolus vulgaris seed infusion. For this purpose, a drop of gel medium (sodium metasilicate of 1.06 specific gravity and 3M acetic acid solution) at pH 5.02-5.17 was placed in the middle of the glass slide and converted into gel. A single drop of 1 M oxalic acid was dropped to the left, and 1 M calcium chloride and magnesium acetate (1:1) solution fell to the right side of the adequately formed gel. The glass slide was observed under microscope till it was completely dried. In the case of the crystal inhibition study, a drop of Phaseolus vulgaris infusion was also added on the right side just after adding calcium chloride and magnesium acetate solution. The results without infusion showed detailed morphology and aggregation patterns of observed crystals as donut, dumbbells, needles, platy, prismatic, rosette, round edges, and loose and compact aggregates. All infusions of Phaseolus vulgaris showed defective crystals. 5 % infusion inhibited crystals of all morphologies with their loose and compact aggregates except rosettes. Whereas 10 and 15 % infusion converted the rosette crystals into ineffective calcium oxalate dihydrate crystals of tetragonal bipyramidal and elongated rod shape. The microscopic study of calcium oxalate crystal growth and its inhibition is simple and provides rapid qualitative analysis of antiurolithiatic activity.

Dr. salman ahmed

Business nowadays has no boundaries of time, place, or information, so any firm must evaluate its performance regularly to ensure long-term viability. This study aims to determine the impact of employees’ motivation and job training on company performance in a family business called PT Anugrah Mandiri. It is an automotive spare parts distribution company in Medan, Indonesia established in 2010. As a family business run by many family members, PT Anugrah Mandiri tends to undervalue the importance of providing motivation and delivering practical training to its employees. This results in most employees being overwhelmed, and the business performance is decreasing. As this study's quantitative research method shows, motivated and skilled employees are the keys to a successful firm. The instruments used to collect data are questionnaires about employees’ motivation, job training, and company performance, and then processed using SPSS. Saturation sampling is used as the sampling method by administering the questionnaires to 50 employees of PT Anugrah Mandiri. The data analysis tool in this study is a multiple linear regression by carrying out a classic assumption test continued by testing the partial hypothesis or t-test, the simultaneous hypothesis test or the F test, and the calculation of the coefficient of determination. The statistical result shows that company performance increases by 0.422 and 0.384 when employees’ motivation and job training increase by 1 unit. All hypotheses in this research are accepted, and it can be concluded that employees’ motivation and job training influence company performance.

L

Several studies demonstrate a strong correlation between talent and organizational performance. This view has led to continued improvement of methodologies, human resource scorecards, benchmarking, and engaging in best practices aimed at attracting both talent and better business management. As all these underline advancements of organizational strategic goals, it also determines the development and alignment of individual performance (Savanevičienė and Vilčiauskaitė, 2017, pg. 247). Although most of the studies involve for-profit corporations incorporating them in various industries proves to be both logical and psychologically sound. Regarding this project, the major focus is on determining talent strategies that best companies use to attract and retain people. For the project, Deloitte has been chosen as the reference organization for the strategies it uses and how its human resource management has been able to sustain attracting and retaining good talent.

Zamzam abdelazim

Cloud computing is a technology of delivering resources such as hardware, software (virtual too) and bandwidth over the network to the consumers worldwide. All the services are requested and accessed through a web browser or web service. The main advantage that cloud is provided to the nation worldwide is that it is not so easily affordable to one and all. Multi-conglomerate companies invest a lot of money on the cloud and let people access it for a smaller cost and even free at the lowest level of the consumer chain. In this paper we address to the problems that the cloud technology faces and how it can be overcome.

Pavan m

All the people who need loan may turn to their local banks, credit unions or peer to peer lenders. Every lending institution has its own advantages and drawbacks. In this scenario credit risk management becomes increasingly important element as the same is concerned with managing the financial debts and safeguarding the interest of the banks. The purpose of credits given by banks is to earn interest and make profits. The important function of credit management is to decide how much credit should be given to the borrower and ensuring compliances with the credit terms of repayment and avoid Non-Performing Assets (NPA) to the banks. Credit risk is the biggest risk the bank faces by the virtue of nature of business, inherits. The ability of commercial banks to formulate and adhere to policies and procedures that promote credit quality and curtail non-performing loans is the means to survive in the stiff competition. Inability to create and build up quality loans and credit worthy customers leads to default risk and bankruptcy as well as hamper the economic growth of the country

Shaila kamath

English Corner extracurricular activities are one of the choices for students to be able to learn English with more fun. Through the English Corner extracurricular program, the Madrasah provides provisions for its students to face the era of the industrial revolution 4.0. The purpose of this research is to add insight and to know the mechanism of the English corner extracurricular through the development, implementation, assessment, and evaluation of the English corner extracurricular in the 4.0 revolution era at MI Roudlotul Ulum Banyuwangi. This type of research is qualitative research with a descriptive design. Data collection techniques using interviews, observation, and documentation. Data analysis used the concept of Miles and Huberman. The validity of the data was measured by means of triangulation of sources and techniques. The results showed that 1). The development of the English corner extracurricular in facing the 4.0 industrial revolution pays attention to human resources, needs, infrastructure, talents, and interests. 2). The implementation of the English corner extracurricular is almost the same as learning in general and is made more relaxed so that it is more comfortable in its implementation. 3). This English corner extracurricular assessment uses a written manual assessment, after which it is recapitulated and entered into the Digital Report Card Application (ARD). 4). This English corner extracurricular evaluation is carried out every six months or at the end of the semester, taking into account the development and implementation that was carried out in the previous semester.

Educare: journal of primary education

Background: There is great promise for improving nutrition and health thanks to phytonutrients' antioxidant qualities and health advantages. Their capacity to combat oxidative stress and associated illnesses emphasizes the importance of precisely evaluating their antioxidant characteristics. Objective: This study concludes by providing a comprehensive and critical critique of the current approaches to measure the antioxidant activity of phytonutrients. It dives into the fundamentals, benefits, drawbacks, and most recent developments of commonly used antioxidant assays, giving the reader a comprehensive grasp of the topic. This recapitulation of the review's goal in the end reinforces the reader's primary takeaway. Methods: Research on several antioxidant tests, such as FRAP, ORAC, DPPH, and ABTS, is consolidated in this review. It looks at each assay's performance traits, technological advances, and techniques. The review also assesses the incorporation of many assays to thoroughly examine phytonutrient potency and its uses in the food industry and nutritional science. Results: The review shows how antioxidant tests have advanced significantly, improving sensitivity, accuracy, and physiological relevance. It demonstrates how these tests can be used practically to guarantee food quality, create supplements, and offer nutritional advice. The paper also lists the difficulties today, including the intricacy of antioxidant mechanisms, test variability, and the requirement for assay standardization. The practical value of the research is emphasized by highlighting the significance of antioxidant tests for quality assurance, adulteration detection, and shelf life extension in the food business. Discussion: Scientists, doctors, and business experts interested in evaluating and applying phytonutrients will find this review helpful. It emphasizes how crucial it is to improve antioxidant testing to ascertain the possible health advantages and therapeutic uses of phytonutrients. The review highlights the need for increased test sensitivity, accuracy, and relevance while discussing the benefits and drawbacks of the available techniques. It draws attention to the importance of strong and trustworthy antioxidant tests to maximize the use of phytonutrients in food quality control and pharmaceutical research. Prospects: Future directions seek to address the challenges discovered through the development of multidisciplinary research and testing technologies. Novel approaches will advance our knowledge of phytonutrient potency and aid in developing medicines and nutraceuticals. This study highlights the significance of trustworthy assays for understanding and utilizing phytonutrients, providing academics and professionals in the business with vital insights.

Dr. salman ahmed

Indoor thermal comfort and air quality are essential for occupant well-being, while simultaneously optimizing energy consumption in buildings. Achieving a balance between these factors presents a significant challenge, as indoor environments are dynamic and energy demands fluctuate. By modifying ventilation rates in response to real-time data, demand-controlled ventilation systems can reduce energy consumption and enhance indoor comfort and air quality. However, optimizing these systems with advanced predictive models remains a complex task. To address this challenge, this publication proposes a Dual-Stream Multi-Dependency Graph Neural Network (DMGNN)-based energy-efficient ventilation management technique that maximizes indoor air quality and thermal comfort. The suggested method seeks to enhance thermal comfort and air quality by maximizing heating, ventilation, and air conditioning (HVAC) operations while reducing energy consumption. Initially data are collected from an Indoor Air Quality Monitoring Dataset. The DMGNN is employed to capture the complex dependencies between environmental factors such as temperature, humidity, and CO2 concentrations, considering both temporal and spatial relationships. Implementing the proposed system and evaluating it through simulations in various building environments demonstrates notable improvements in thermal comfort, indoor air quality, and energy economy. The suggested system’s performance is contrasted with that of other current methods, showing superior energy efficiency and optimization of both indoor air quality and occupant comfort. This study presents an innovative, scalable framework for smart building management, promoting sustainable energy solutions.

Dr h shaheen

Fueled by the recent advancements in pervasive environment, affluent context aware systems is among the rousing in computing today, including embedded environment, different wireless network technology, electronic communication and so on. Context-Aware Collaborative Filtering using Genetic Algorithm approach resulted in an improved mobile business model by determining optimal similarities between contexts. In this work, we plan to devise a hybrid framework called Multi-distribution Perceptron and Hidden Markov Model to smoothen the mobile networks with different degrees of context- confidence. Initially, Multi-distribution Layer Perceptron Model is designed aiming at improving the precision rate with the aid of Multi-distribution Bayesian Posterior measure. Experimental analysis shows that the M-PHMM framework is able to reduce the computational complexity for obtaining user patterns by 26.05% and improve the precision rate by 18.90% compared to the state-of-the- art works.

Dr h shaheen

To report a case of neurogenic stress cardiomyopathy post-trauma, managed using Non-Invasive Cardiac Output Monitor (NICOM)-guided conservative therapy. A middle-aged patient with traumatic subdural and subarachnoid hemorrhages developed hemodynamic instability. ECG showed QT prolongation; echocardiography revealed apical ballooning. We used NICOM which indicated low cardiac output (3.5 L/min). Fluids and inotropes were adjusted based on NICOM trends. The patient showed gradual hemodynamic and cardiac recovery. NICOM guided safe de-escalation of inotropes. Echocardiography normalized, and the patient was discharged. NICOM can be used for precise, non-invasive hemodynamic monitoring, aiding recovery in stress cardiomyopathy. Keywords: Traumatic brain injury, Takotsubo cardiomyopathy, Stress cardiomyopathy, Non-invasive cardiac output monitoring, Hemodynamic instability, Apical ballooning, Neurocritical care.

Journal of scientific innovations in anesthesiology

This paper investigates the transformative potential of Indian Knowledge Systems (IKS) in modern business and management practices, aligning with India's vision for "Viksit Bharat 2047"—a roadmap toward becoming a developed nation by 2047. Integrating ancient Indian wisdom with advanced Artificial Intelligence (AI) provides an innovative framework for enhancing decision-making, sustainability, and innovation across diverse industries. This study aims to incorporate key IKS principles such as holistic management, ethical leadership, and community-centered business models into AI-driven methodologies to create a forward-thinking approach in Indian business contexts. Using a mixed-method research design, the study combines qualitative insights from traditional Indian texts with quantitative analysis of case studies where IKS principles are applied in contemporary businesses. The findings reveal that concepts like ―Dharma‖ (ethical responsibility), ―Artha‖ (resource management), and ―Karma‖ (action-driven leadership) play a crucial role in corporate governance, social responsibility, and achieving sustainable development goals when combined with AI's analytical power. This synergy addresses current challenges, including environmental sustainability, social equity, and ethical governance. The research demonstrates that a balanced integration of AI and IKS can foster inclusive and sustainable growth, supporting India's self-reliance and competitiveness on a global scale. The paper provides a roadmap for academics, policymakers, and business leaders to leverage IKS with AI, aiming for an innovative and resilient India by 2047.

Dr tatayya bommali

The study identified the level of competencies and the extent of professional development needs of kindergarten teachers in the Sultan Kudarat Division, during the school year 2019 - 2020. The study employed a descriptive method. The study involved 54 kindergarten teachers in the division in accomplishing the 12-item self-assessment instrument. Data were analyzed using descriptive statistics. The results revealed that kindergarten teachers have a high level of competencies in content knowledge and pedagogy, learning environment and diversity of learners, curriculum and planning, and assessment and reporting. These indicate that they possess almost all of the competencies of efficient teachers. Results further revealed a very high extent of professional needs in content knowledge and pedagogy and the learning environment and diversity of learners, while they had a high extent of professional needs in the remaining domains. Since they reported very high priorities in content knowledge and pedagogy and the learning environment and diversity of learners, these areas would be the main considerations in the crafting of a professional development plan.

Manuel caingcoy

During COVID-19 pandemic health professional need to develop good communication skills. Good communication skills will lead to professionalism. The information that are given to patients, their families and the community has to be transparent, true and scientifically relevant. The awareness one creates about the pandemic includes mode of infection, transmission, symptoms, vaccines, vaccination, viral heterogeneity and mutations. Such transmission of true information requires proper training of health personnel including the social media in developing good communication skills

Mediterranean journal of pharmacy and pharmaceutical sciences

One of the unique features of Indian society is prevalence of caste system which was originated thousands of years back to demarcate the people engaged in different occupation or jobs. Initially it was not much rigid but gradually people belonging to upper castes for their own selfish means to maintain their monopoly made this arrangement hereditary and started treating people of lower castes disgracefully. For preservation of this system, people started controlling their women to prevent inter-caste marriages and the concept of endogamy came up. This robbed away many types of freedom from women. For women belonging to lower castes, this situation is worse as they are doubly subjugated on the basis on caste as well as gender. Men belonging to their own caste treat them as secondary beings. This paper throws light on this intersection. How intersection of these two kinds of inequalities place them at the lowest position in Indian society. Dr. B.R. Ambedkar rises as their leader who all his life worked for empowerment of downtrodden section of society. He argues that education is the primary tool for evading these differences among people. He further emphasizes to adopt the concept of exogamy to break the backbone of Indian caste system and to immediately leave a religion or culture which legitimizes such system of inequality among people of the same land.

Swati sharma

Penggunaan aplikasi smartphoneuntuk memasarkan produk industri rumah tangga telah mendapatkan perhatian yang signifikan dalam beberapa tahun terakhir. Aplikasi seluler adalah alat yang efektif untuk pengembangan kewirausahaan, khususnya bagi wirausahawan muda, dengan potensi signifikan untuk meningkatkan jangkauan pasar dan keterlibatan pelanggan. Pengabdian masyarakat ini berlangsung di Rumah Rahpia, sebuah panti asuhan bergaya keluarga yang berperan penting dalam pengasuhandan pengembanganremaja di Medan, Indonesia. Kegiatan penyuluhan dan pendampingan dalam pemasaran produk dilakukan selama 4 bulan mulai dari Maretsampai Juni2022. Pemberdayaan generasi muda di panti asuhan dengan keterampilan kewirausahaan diyakini dapat berkontribusi terhadap pengembangan pribadi dan kesuksesan masa depan mereka. Selain itu, menumbuhkan kewirausahaan pada usia muda dapat membantu mereka membangun jalur karier yang realistis dan beradaptasi dengan tren global. Oleh karena itu, mendidik generasi muda di panti asuhan tidak hanya membekalimereka dengan keterampilan dan pengetahuan penting namun juga berkontribusi terhadap kesejahteraan dan prospek mereka secara keseluruhan. Melalui hasil wawancara dengan peserta menunjukkan bahwa penjualan produk meningkat dengan kualitas produk lebih baiksetelah dilakukannya kegiatan pengabdian kepada masyarakat ini.

L

Physically unclonable function (PUF) is a hardware security module preferred for hardware feature based random number and secret key generation. Security of a cryptographic system relies on the quality of the challenge-response pair, it is necessary that the key generation mechanism must unpredictable and its response should constant under different operating condition. Metastable state in CMOS latch is undesirable since it response becomes unpredictable, this feature used in this work to generate a unique response. A feedback mechanism is developed which forces the latch into the metastable region; after metastable state, latch settle to high or state depends on circuit internal condition and noise which cannot be predicted. Obtained inter hamming variation for 8 PUF is 51% and average intra hamming distance is 99.76% with supply voltage variation and 96.22% with temperature variation.

Abhishek kumar

Higher Education has an important role in the task of rebuilding a nation and it paves the way for overall development of a nation. The twentieth century has witnessed several revolutions like Green revolution, White revolution, I.T revolution etc; transforming human civilization in to new heights. At the start of 21st century, there is a lot of importance given to higher education. Every country realizes the value of higher education and the benefits accrue from it. There is a greater importance attached to higher education. “The social demands for higher education continue to increase. Indian higher education has a rich and complex history that spans millennia. This abstract provides an overview of the key developments in Indian higher education, highlighting its evolution from ancient times to the modern era. The history of Indian higher education is marked by the establishment of ancient centers of learning, the influence of various empires and dynasties, colonialism, and post-independence reforms. This abstract also touches upon the challenges and opportunities that have shaped the landscape of higher education in India.The history of Indian higher education can be divided into several distinct periods. In ancient India, centers of learning such as Takshashila and Nalanda emerged as renowned seats of knowledge, attracting students and scholars from across the world. These institutions laid the foundation for a tradition of rigorous intellectual inquiry

Dr gedam kamalakar

Impurity is something that is impure or makes something else impure. An impure substance may be defined as follows: a substance of interest mixed or impregnated with an extraneous or usually inferior substance, from the standpoint of its usage, the drug substance is compromised in terms of purity even if it contains another material with superior pharmacological or toxicological properties. The impurity may be developed either during formulation, or upon aging of both API’s and formulated API’s in medicines. The presence of these unwanted chemicals, even in small amount, may influence the efficacy and safety of the pharmaceutical products. The impurities are not necessarily always inferior. Highly sophisticated instrumentation, such as mass spectra meters attached to a Gas Chromatography or HPLC, are inevitable tools in the identification of minor components (drugs, impurities, degradation products, metabolites) in various matrices. Present article reveals different impurities found in the API’s, methods for identifying them and the possible measures to deal with the interferences caused by them in pharmaceutical analysis.

Prasanna pradhan