Information and communication technology is an instrument in addressing some of the issues of Indian higher education however; there are certain drawbacks to using ICT to enhance teaching and learning. The present research was carried out in The Maharaja Sayajirao University to study the impediment faced by them in the use of ICT in their professional work. Quantitative data was collected from two hundred and ninety faculty members through the purposive and convenient sampling method. The data indicate that faculty members faced technological infrastructure-related impediments such as lack of smart boards, lack of computers, uneven bandwidth of internet, slow internet connection. It is suggested that an adequate atmosphere be developed in the institution that would encourage faculty members to use ICT.

Maniar avani

The chosen organisation for this research work is Tesco. Founded in 1919, Tesco is one of the most renowned retailing brands operating in the global market (Azad, 2018). It focuses on selling a wide variety of products to its customers at low prices. Since its inception, the organisation has focused on maintaining high efficiency in its internal management. This is done with the help of effective human resource practices and organisational behaviour. The organisation always seeks to maintain good relations with its employees to work hard to attain the organisational objectives. This research work will focus on understanding and analysing the concept of organizational behaviour. This will be done by applying the different concepts and theories of organisational behaviour in reference to Tesco. Concepts such as motivation, leadership, teamwork, change management, and many more will be discussed in this research work.

Zamzam abdelazim

Background: Hypertension (HTN) has emerged as a significant public health challenge and a leading cause of mortality and morbidity in developing countries like Bangladesh. Objective: This study aimed to assess the prevalence of hypertension and its associated risk factors among resi dents of Dhaka, the capital of Bangladesh, during the COVID-19 pandemic. Methods: A cross-sectional study was conducted using a multistage random sampling technique to select 305 individuals from Khilkhet Thana in Dhaka North City Corporation. Data were collected through direct surveys using a modified version of the WHO STEPS questionnaire and analyzed using SPSS version 22 software. Findings: The study identified a 34.4 % prevalence of HTN among the participants, with 46.2 % of hypertensive individuals being under 40 years of age. Of the 105 hypertensive individuals, 65 % were newly diagnosed during the study, and 11 previously diagnosed individuals were not on any medication. A significant association (P < 0.001) was observed between the prevalence of HTN and inadequate intake of fruits (OR = 3.129, 95 % CI = 1.912–5.122, χ2 = 21.328), insufficient vegetables consumption (OR = 2.199, 95 % CI = 1.356–3.565, χ2 = 10.373), high intake of fatty foods (OR = 2.387, 95 % CI = 1.465–3.890, χ2 = 12.454), and excessive salt consumption (OR = 2.771, 95 % CI = 1.677–4.579, χ2 = 16.310). Additionally, the prevalence of HTN was notably higher among overweight (46.70 %) and at-risk (22.90 %) individuals, based on Body Mass Index (BMI) and waist-to-hip ratio (WHR), respectively. The study also found significant correlations (P < 0.001) between HTN and factors such as smoking (OR = 2.824, 95 % CI = 1.601–4.980, χ2 = 13.432), kidney disease (OR = 7.534, 95 % CI = 2.694–21.070, χ2 = 19.282), general stress (OR = 3.692, 95 % CI = 2.179–6.255, χ2 = 24.896), COVID-19 related stress (OR = 3.511, 95 % CI = 2.116–5.826, χ2 = 24.712) and sleeping pattern (OR = 5.798, 95 % CI = 3.404–9.875, χ2 = 45.724). Conclusions: The high prevalence of HTN, particularly among younger individuals during the COVID-19 pandemic, highlights the urgent need for nationwide surveys, surveillance, and clinical research to accurately depict the true burden of HTN in Bangladesh.

Arafat hassan razon

A burning sensation on eating spicy foods purportedly supports the role of capsaicin, an active component of chili peppers, in the etiology of oral submucous fibrosis (OSF). Although the mast cell mediators and activated P2X receptors induce a constant burning sensation through an ATP-dependent mechanism, it is the activation of the transient receptor potential vanilloid 1 (TRPV-1) receptor by capsaicin that aggravates it. The molecular basis for the burning pain in OSF is thus attributable to the activation of TRPV1. There is overwhelming evidence that confirms capsaicin has more of a protective role in attenuating fibrosis and is potentially therapeutic in reversing conditions linked to collagen accumulation. The activation of TRPV-1 by capsaicin increases intracellular calcium ([Ca2+]i), upregulates AMP-activated protein kinase (AMPK) and Sirtuin-1 (SIRT-1), to enrich endothelium-dependent vasodilation via endothelial nitric oxide synthase (eNOS). The induction of vasodilation induces antifibrotic effects by alleviating hypoxia. The antifibrotic effects of capsaicin are mediated through the upregulation of antioxidant enzymes, downregulation of inflammatory genes and suppression of new collagen fibril formation. Capsaicin also demonstrates an anticarcinogenic effect by upregulating the cytotoxic T cells and downregulating regulatory T cells through the inhibition of angiogenesis and promotion of apoptosis. Judicious administration of capsaicin with an appropriate delivery mechanism may have therapeutic benefits in reducing pain sensation, rendering antifibrotic effects, and preventing the malignant transformation of OSF. This paper provides an overview of the molecular basis of capsaicin and its therapeutic application as an antifibrotic and anticarcinogenic agent for the treatment of OSF

Mohit sharma

One of the most important challenges for a company is to manage its supply chain efficiently. One way to do this is to control and minimize its various logistics costs together to achieve an overall optimization of its supply network. One such system that integrates two of the most important logistics activities, namely inventory holding and transportation, is known as the inventory routing problem. Our replenishment network consists of a supplier that uses a single vehicle to distribute a single type of item during each period to a set of customers with independent and deterministic demand. The objectives considered are the management of supplier and customer inventories, the assignment of customers to replenishment periods, the determination of optimal delivery quantities to avoid customer stock-outs, the design and optimization of routes. A genetic algorithm (GA) is developed to solve our IRP. Different crossover structures are proposed and tested in two sets of reference instances. A comparison of the performance of different crossover structures was established. Then, it was used to find the most appropriate crossover structure that provides better results in a minor computation time. The obtained results prove the competitiveness of GAs compared to literature approaches, demonstrate the performance of our approach to best solve large scale instances and provide better solution quality in fast execution time.

Mohamed salim amri sakhri

Overpopulation is a global problem which affects almost everyone in the globe by reducing the available natural resources in the existence. An epidemiological survey was conducted with the aim to assess the people’s response towards overpopulation and its harms to them. The study was conducted based upon descriptive survey design using interview method. The study comprises 80 people residing in selected rural area. The data was collected based on purposive sampling using checklist. The study reveals that most of the people are residing by doing unskilled work due to unemployment with poor living standard.

Neeraj kumar bansal

Justificativa e objetivo: O uso inadequado da estatística básica é o maior responsável peloerro de interpretac ̧ão dos artigos científicos. O objetivo deste artigo de revisão foi rever algunstópicos básicos de estatística para alertar autores e leitores sobre a importância do relatoadequado da estatística básica.

Kamal singh

Humans have used natural products to treat different pathological conditions since immemorial. Numerous plants have been reported to have antitussive activity. Our present study aimed to evaluate the ethanolic extract of Arenaria serpyllifolia (Carophyllaceae, Whole plant), Caesalpinia pulcherrima (Caesalpiniaceae, Aerial parts) and Fragaria nubicola (Rosaceae, Whole plant) for antitussive activity at the doses of 200, 400 mg/kg in healthy albino rats. Cough is a symptom and defensive reflex of removing the toxic, irritating substances and pathogens from the larynx, trachea and bronchi. Cough is usually considered a disease related to the lungs. Several substances are responsible for the stimulation of cough reflexes. Among the most common are dust, histamine and bronchoconstriction. Arenaria serpyllifolia is a small annual herb commonly called Thyme-leaved sandwort, found in uncultivated land, arid meadows and cliffs. Caesalpinia pulcherrima is an ornamental plant, usually 2 m tall, known as a Peacock flower. Fragaria nubicola grows in wooded valleys, forest margins and meadows. It is commonly known as wild strawberry. These plants have been used traditionally for cough suppression by different societies. In this study, cough was induced by using the sulphur dioxide induction method. Animals were divided into eight groups of ten animals each, and all the drugs were administered orally. Group I was the control group, while Group II was the standard. A dose-dependent inhibition of cough was observed for all extracts. At 200 and 400 mg/kg doses, all three extracts proved highly significant compared to standard. So, it proves and supports the traditional use of plants for relieving cough.

Dr. salman ahmed

Financial Inclusion is emerging as a new paradigm of economic growth that plays major role in driving away the poverty from the country. It refers to delivery of banking services to masses including privileged and disadvantaged people at an affordable terms and conditions. Financial inclusion is important priority of the country in terms of economic growth and advances of society. It enables to reduce the gap between rich and poor population. In the current scenario financial institutions are the robust pillars of progress, economic growth and development of the economy. When and where all citizens are participated in financial system, the economy and system will become very strong. In this regard the research article was focuses on customer perceptions towards inclusive banking practices.

Dr tatayya bommali

Increasing presence of women in economic pursuits like entrepreneurship activities is believed to be the result of development policies. This belief ignores the role of socioeconomic factors in the growth and development of women entrepreneurship. Many women entered the world of business and they have become successful entrepreneurs in various business activities. Women entrepreneurs in Dakshina Kannada district have set up business ventures in a range of industries. The study has been conducted to know the extent of problems faced in managing work and life by women entrepreneurs. Majority of the respondents started their business or service to become independent and to meet the financial needs of their family. From the study it has to be found that majority of the women find it difficult to manage their work and family and they are trying to overcome these difficulties by time management and with the help of their family members.

Thara s shetty

In the context of emerging sustainability challenges, demarketing has continued to draw the attention of academicians and practitioners globally over the past few years. It is interesting to note that demarketing is as old as marketing itself, yet its application and scope have grown from the past two decades only. Kotler and Levy, (1971) has defined demarketing as “that aspect of marketing which deals with discouraging customers in general or a certain class of customers in particular on a temporary or permanent basis”. This systematic literature review attempts to enrich the discussion on demarketing research through a systematic and comprehensive review of 64 articles published between 2000 and 2022. Using TCCM framework, we present relevant theories, research contexts, study characteristics, and methodologies used in demarketing research. Our review (1) Presents a systematic and comprehensive overview of the research in demarketing over the last two decades (2) Examines studies in demarketing within the framework of ‘triple bottom line’ approach for sustainability (3) Suggests a suitable definition of demarketing considering its exorbitant application within the sustainability context (4) Identify gaps and sets agenda for future research. Our systematic literature review found that research in demarketing has been growing considerably over the past two decades, twice as much in the last decade compared to the previous decade with spill-over to new sectors. The literature review, through the lens of ‘triple bottom line’ approach, is able to establish that demarketing can be employed to effectively address the sustainability challenges encountered by policymakers and practitioners.

Jeevan lawrence

Cloud computing is a technology of delivering resources such as hardware, software (virtual too) and bandwidth over the network to the consumers worldwide. All the services are requested and accessed through a web browser or web service. The main advantage that cloud is provided to the nation worldwide is that it is not so easily affordable to one and all. Multi-conglomerate companies invest a lot of money on the cloud and let people access it for a smaller cost and even free at the lowest level of the consumer chain. In this paper we address to the problems that the cloud technology faces and how it can be overcome.

Pavan m

Brucellosis is a zoonotic infection often linked to direct or indirect exposure to animals or unpasteurized dairy products. Atypical presentations in patients without classical risk factors pose significant diagnostic and management challenges. A 68-year-old woman presented with a 2-month history of burning pain involving cervical and lumbar regions, associated with weight loss, decreased appetite, and subjective fever. Examination revealed paravertebral tenderness and left knee swelling with effusion. Previous MRI showed multifocal marrow edema and soft tissue thickening in the lumbar spine, suggesting infection or inflammation. The patient denies exposure to unpasteurized dairy products, raw meat, or animals. Brucella serology revealed positive IgG with Brucella melitensis titer 1:160, later confirmed by blood cultures. PET imaging demonstrated multifocal metabolically active arthritic changes involving the spine, shoulders, and knees. Arthrocentesis confirmed inflammatory arthritis due to brucellosis. The patient was started on doxycycline, rifampin, and a 14-day course of intravenous gentamicin. During hospitalization, management was complicated by persistent knee pain and swelling requiring multimodal analgesia. Spinal brucellosis in the absence of classical risk factors is an odd presentation, emphasizing the importance of maintaining a high index of suspicion in endemic regions. Advanced imaging and microbiological confirmation are pivotal procedures in diagnosis. Early recognition of atypical brucellosis is critical to prevent complications and improve outcomes.

Karishma

The National Education Policy 2020 (NEP 2020) aims to modernize India's higher education system by prioritizing the learner, increasing accessibility, and fostering inclusivity. It emphasizes the importance of libraries as information hubs and libraries, with the policy focusing on their resources and facilities. The policy requires sufficient library employees to manage facilities, create suitable career courses, and foster cooperation between educational institutions and libraries. Infrastructures for libraries are crucial for adult education, lifelong learning, and study. Schools, school complexes, and public library locations should be well-designed and equipped with information and communication technology. Central and state governments are responsible for creating and funding libraries, ensuring they are available and reasonably priced for everyone in the nation. Digital libraries and online resources are included in the NEP 2020, with efforts to improve accessibility online and expand the reach of digital libraries. The policy also includes provisions for enhancing all current libraries, establishing reading rooms and rural libraries in underprivileged areas, making reading materials in Indian languages widely accessible, opening child-friendly and transportable libraries, creating social literary societies, and promoting better partnerships between educational institutions and libraries. The government is focusing on providing top-notch online resources for education, including digital resources, online courses, applications, satellite TV channels, online books, and IT-equipped libraries and Adult Education Centers across India. The policy has significantly raised the standard of instruction in India's higher education establishments, providing students with a more comprehensive and holistic education. Preliminary findings suggest that the policy has had positive effects, but significant human, material, and technological resources are needed for its success. The policy also seeks to increase diversity in higher education by providing financial aid and scholarships to underrepresented groups.

Dr. awadhesh singh gautam

Background: Lichen planus (LP) is a papulosquamous cutaneous disorder that manifests as intensely itchy violaceous flat-topped polygonal papules and plaques. To compare the efficacy of topical clobetasol propionate 0.05% versus topical tacrolimus 0.1% in the treatment of LP. Methods: This prospective Comparative Study was conducted at the Dermatology Department, Services Institute of Medical Sciences (SIMS)/Services Hospital, Lahore, from May 1, 2022, to April 30, 2023. Ethical approval was obtained from the institutional review board at the Department of Dermatology, SIMS/Services Hospital, Lahore. A total of 80 patients were selected after fulfilling the selection criteria. The study participants were placed into two groups, A and B. In group A, the patients were advised to use the topical application of clobetasol propionate (0.05%) ointment twice daily. In group B, tacrolimus ointment (0.1%) was used twice daily. Treatment response was assessed at 3 weeks, and then finally efficacy was evaluated at 6 weeks. Results: Treatment efficacy was observed in 34 patients (42.5%). Group A (Clobetasol) demonstrated a significantly higher efficacy of 55% compared to 30% in Group B (Tacrolimus; p = 0.024). Conclusions: The 0.05% clobetasol propionate topical formulation demonstrated superior efficacy in treating LP compared to 0.1% topical tacrolimus. Further validation of these findings through large-scale clinical trials is warranted.

Karishma

Social Network sites are one of the most prominent websites used in almost every facet of life. A social network reflects relationships among social entities, including acquaintances, co-workers, or co-authors. With the extreme success of Social networks, the misuse has also been escalated and unlocked the way for various illegal behavior and security threats. Social Network anomaly detection has become a critical topic to be explored by researchers. The nature of the input data is a significant aspect of an anomaly detection technique. In the field of anomaly detection in the social network, input networks can be classified as static or dynamic, Attributed or unattributed. The number of nodes and the connections between the nodes in static networks would not change with time. Attribute networks are pervasive in various domains and constitute a vital element of modern technological architecture, where node attributes support the topological structure in data exploration. While social networks build up over time, evaluating them as if they had been static is very beneficial. Numerous studies have been done for Anomaly detection, but to the best of our knowledge, research in static attributed anomaly detection has been very limited. This review tries to portray earlier research on detecting anomalies for social static attributed networks and thoroughly discusses state-of-the-art embedding approaches

Mohd haroon

This paper examines the influence of empowerment on job satisfaction in five-star hotels in Jordan. The influence of empowerment on job satisfaction remains a relatively unexplored area. A 52-item questionnaire, measuring empowerment and job satisfaction, was distributed to 332 employees in 12 five-star hotels in Jordan with a 56% response rate. Principal components analysis determined the factor structure and regression analysis determined the influence of empowerment on job satisfaction. The results revealed both structural and psychological empowerment have significant individual influences on job satisfaction, but more significant when structural and psychological empowerment are combined. Most of previous studies were conducted in western economies and little in the Middle East generally and Jordan in particular. This research contributes to the literature by including both dimensions of empowerment where previous scholars used only one.

Mukhles m. al-ababneh

Colon is part of the digestive system in the human body responsible for absorbing water and nutrients from food residues. There are many problems affecting the colon including irritable bowel syndrome, constipation, hemorrhoids, anal fissures, abscess, colitis and colon cancer which considered one of the most common diseases among the Libyan community. The aim of this study was to search the presence of colonic disease and the tendency of those diseases to transform into colonic cancer at Benghazi medical center in Benghazi-Libya. A survey was comprised of 15 questions concerning colon diseases, proper diagnosis and treatment type. The survey was distributed to the physician specialized in medicine at Benghazi medical center and they fill it voluntary. The initial part of the questionnaire designed to obtain demographic data concerning the physicians who diagnose the colon illness. The rest part of the questionnaire was concerning special questions to define frequency of the diagnosed disease. There were 20 participants at this study. The response to all questionnaires were collected and analyzed for drug use, patients and disease distribution. In conclusion, this study demonstrates that the correct diagnosis, prescribing the appropriate treatment for the colon disease and using the medicine properly is one of the most important things that help in treating the disease and reducing its exacerbation. In some cases, eradication procedures may be required if the medicine is not sufficient to treat the disease without the need for operations

Mediterranean journal of pharmacy and pharmaceutical sciences

Background: Epilepsy and cerebral palsy (CP) are reported as the two most common indications for electroencephalogram (EEG) requests in children in Nigeria. Although several studies have examined epilepsy and EEG findings in the country, most have not documented the conditions under which EEG recordings were performed—whether during wakefulness, natural sleep, sleep deprivation, or drug-induced sleep. This study aimed to compare the effectiveness of sleep deprivation and the use of melatonin in achieving sleep EEG recordings in children with epilepsy and CP versus those with epilepsy without CP, at the Pediatric Neurology Clinic of Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria. Methods: This was a cross-sectional comparative study involving children aged 6 months to 15 years, conducted between March 2022 and February 2023. A total of 121 subjects with epilepsy associated with CP (Group 1) and 124 subjects with epilepsy not associated with CP (Group 2) were consecutively recruited. Conventional inter-ictal sleep EEG recordings were performed using an EEG machine (Model: Satellite P200-132, Toshiba Europe GmbH, DC 19V, 3.4A). Data were analyzed using SPSS version 25.0, and a p-value of <0.05 was considered statistically significant. Results: Of the subjects with epilepsy and CP (Group 1), 67 (55.4%) achieved sleep EEG recordings following sleep deprivation, while 54 (44.6%) required sleep induction with melatonin. Among subjects with epilepsy without CP, 107 (86.3%) attained sleep EEG recordings after sleep deprivation, whereas 17 (13.7%) required melatonin-induced sleep. The difference between the two groups regarding the need for melatonin to induce sleep was statistically significant (p < 0.001). Conclusions: Sleep deprivation was more effective in achieving sleep EEG recordings in children with epilepsy who did not have CP.

Karishma

Obesity is a complex and challenging global public health concern. It is a major disease involving excessive fat accumulation that may impair health. Obesity is dangerous and has been related to a range of long-term health issues that can impact adults and children. According to the World Health Organization, more than one billion people worldwide are obese as of March 2022. In the Libyan situation, the prevalence of obesity has increased among the public over the last decade. This cross-sectional survey-based study is conducted by using self-structured designed questionnaire to evaluate the use of anti-obesity drugs and herbal products among Libyan people. Additionally, considered as an indirect method, pharmacist performance in obesity management was also evaluated. The investigators collected interview data from three different cities in the Northwest of Libya over a period of five months, 2019. A total of 170 participants who use weight loss products were randomly selected to participate in the study after obtaining their verbal consent. The participants' experience with weight reduction agents revealed that more than half of the participants (52.3%) used herbal products while 32.0% of the participants have used drugs of chemical origin and 15.6% have used both (herbal and drugs). The majority of the participants (91.4%) used these products without medical consultation which in turn led to failure to lose and maintain weight with 74.2% gaining weight after stopping using these products. In conclusion, poor pharmacist intervention in obesity management was revealed where the majority of the participants reported that Libyan community pharmacists had not been offering weight management services, monitoring weight loss progress, or explaining the risks of being overweight or obese.

Mediterranean journal of pharmacy and pharmaceutical sciences