Phaseolus lunatus linn: botany, medicinal uses, phytochemistry and pharmacology

The present review shares an updated data on the botany, distribution, traditional medicinal uses, phytochemistry and pharmacology of Phaseolus lunatus L. All provided information was obtained through Google Scholar, Pubmed, Sci Finder, Scirus, Web of Science and library search.

Dr. Salman Ahmed Dr. salman ahmed

Life skills for enhancing social competence during adolescence

Social competence is often seen as a desirable trait during adolescence as it is considered as a protective factor in resilient individuals. It promotes personal and interpersonal effectiveness by enhancing skills needed for dealing with environmental challenges in daily life situations. Poor social competence has been associated with a number of psychosocial troubles during adolescence, including mental disorders, emotional and behavioral problems. Of the many skill building programs used to enhance adolescent social competence, Life Skills Education and Training have been significant ones. The present study investigates the utility of life skills training in enhancing social competency during adolescence. A pre- and post-test experimental design was used in the study to analyze the stated objectives. Adolescent Social Competency Scale was used to select the study sample. 160 adolescent students (mean age=16.44) who scored low on social competence participated in the study. These were randomly divided into the experimental and control group (n=80), consisting of equal number of male and female adolescents (n=40). Participants in the experimental group were trained on six of the ten core life skills, based on the module prepared by the researcher. The training lasted for 10 sessions following which post-test assessments were done. Data obtained was analyzed using descriptive statistics like mean, standard deviation and inferential statistics including independent sample t-test and repeated measures of ANOVA. The results of the study indicate a significant effect of life skills training in enhancing adolescent social competence, irrespective of gender.

Hita claudia rao

The twenty-five most cited articles about adductor canal block: a bibiliometric analysis from 1980 to 2022

Introduction: Loco-regional anesthesia role is increasingly important in surgery, especially in postoperative pain control. Using ultrasound-guided techniques has made the loco-regional approach increasingly safe and manageable, guaranteeing excellent analgesic results and patient compliance. This bibliometric research aimed to identify the most influential papers on the adductor canal blocks and outline their characteristics. Methods: All articles published from 1980 to 2022 were included in the Web of Science, PubMed, and Scopus databases and found using the keywords “Adductor canal block” or “Saphenous nerve block” or “Peripheral nerve block” or “Hunter canal block” or “Subsartorial canal block” or “ACB” or “Knee” or “TKR” or “TKA” or “Analgesia” or “Arthroplasty” or “Replacement” in the title section had bibliometric analysis performed. The first 25 papers were selected and analyzed by the number of citations. The correlation between numerical variables was evaluated using the Pearson Correlation coefficient. Results: Literature screening found 252 publications. One hundred ten were only about the adductor canal block. Of these, 25 articles were selected for our bibliometric study, published in 8 different journals and with a total number of citations equal to 1.457. “Regional Anesthesia and pain medicine” journal – with 9 articles – was the one that produced the most. There was a significant strong correlation between the n. of citations and the citation rate (R = 0.84, p < 0.001). Conclusion: The purpose of this study is to be a guide on regional anesthesia and, particularly, on adductor canal block, making the most effective as well as the most cited articles available to anesthesiologists or other researchers interested in this topic.

Dario Cirillo Dario cirillo

Equity and equality in higher education-india calling…

Abstract Higher education in India is always a socio-political way and a powerful engine of social mobility. It adds to the benefits to society as more people earning Higher Education credentials. It is proven that college graduates earn more. They are less likely to be unemployed. They are more likely to vote, more likely to volunteer, and more likely to maintain good health. India as a Globalised and developing nation has been little systematically progressing on the educational front since its independence. The government is making progress in reaching out to all the classes of its society. The improvement in the country’s economic front has resulted in the upscaling of communication technology. The advent of the internet, have vastly leveraged the promotion of education across all verticals. But at the same time, the idea of Equity and Equality needs to be redefined in the present context of the newly established notion of ‘Inclusivity’. This paper deliberates on the various ideas and approaches of Higher Education in India on ‘Inclusivity’ in general and Equity and Equality in particular.

Dr. Preeti oza Dr. preeti oza

How to grow urinary stone and gouty crystals on glass slide: exploring morphologies, disease insights, and herbal inhibition strategies

Urolithiasis, the process of urinary stone formation, entails the presence of compact masses like whewellite, brushite, and urate within the urinary system. Gout, characterized by inflammatory arthritis, emerges from the accumulation of urate (MSUM) crystals. In vitro, examinations focusing on the growth of whewellite (COM), brushite (CHPD), and urate (MSUM) crystals on glass slides present a cost-effective approach for gaining valuable insights into urolithiasis and gout. These studies not only delve into crystal growth patterns but also investigate the potential inhibition of crystal growth through the application of plant infusions, thereby laying the foundation for further extensive research in these domains.

Dr. Salman Ahmed Dr. salman ahmed

Short and osce cases in internal medicine: clinical examinations for paces, mrcpi, arab board, and similar examinations (second edition)

The second edition of “Short and OSCE Cases in Internal Medicine” [1] is a useful resource that enables candidates to learn the tricks of the clinical examination when preparing for higher specialist examinations such as MRCP (UK) PACES, MRCPI, Arab Board, and other clinical examinations which use the Objective Structured Clinical Examination (OSCE) format. As compared to the first edition [2], the number of photos and illustrations in the second edition has been considerably expanded to include about 150 photos to enhance the candidate’s learning experience. In addition, the author has revised and updated all sections based on new information and advancements in the medical field. Particular emphasis has been placed on a highly professional approach to the case, a competent, succinct, and relevant clinical examination techniques according to the examiner’sinstruction, and a concise, professional presentation by the candidate. Some mnemonics to help recall long lists also have been included as aide-mémoire.

Karishma Karishma

Phytochemical constituent, cytotoxic activity and outcome on wheat growth parameters possessed by extracts of seaweed collected from libyan coast

Algae are used by human beings for food from ancient times, as they contain a wide range of elements. Using inexpensive, in-house bioassays for screening and monitoring of extracts where the aim of these bioassays is to provide a front-line screen that can be followed up by more specific and expensive bioassays. The phytochemical screening, assessment of toxicity and effects on growth parameters of Traticum sativum of ethanol and dichloromethane extracts of five macro-algal species (two green, two brown and one red) collected from Libyan coast were studied. The Brine shrimp lethality assay was conducted to determine the toxic effects of seaweed extracts on Artemia Salina nauplii larvae and this was to provide a front-line screen that can be backed up by specific and expensive bioassays once the active compounds have been isolated. The effect of seaweeds liquid fertilizer on growth parameters of Traticum sativum were examined using in vitro seed germination in petri dishes bioassay. Seed germination percentage, fresh and dry weight, shoots length and roots length were the parameters recorded in young seedlings post germination. Ethanolic and dichloromethane extracts of the five algae samples represented the presence of several chemical constituents. All extracts exhibited LC50 > 1000 μg per ml. In this study, all algal extracts are non-toxic according to Brine shrimp lethality assay so they may be considered as edible seaweeds. Different effects on growth parameters of Traticum sativum suggested the presence of micro-elements, macro-elements and different concentrations of plant growth hormones.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

Antagonistic potential and plant growth promoting traits of achromobacter xylosoxidans isolated from tannery sludge sample

In the present study, the bacterium Achromobacter xylosoxidans was isolated from tannery effluent sludge sample in Dindugal, Tamil Nadu, India and screened for its bio-control efficacy against selected plant pathogens viz., Alternaria solani, Curvularia lunata and Fusarium oxysporum under in vitro. It was observed that maximum percent inhibition of mycelial growth of C. lunata (95%), followed by A. solani (85%) and F. oxysporum (80%). An attempt was also made for testing its plant growth promoting traits such as production of Indole acetic acid (IAA), phosphate solubilization efficacy, Hydrogen cyanide (HCN), ammonia and catalase production. Significant amount of plant growth promoting traits were noticed. Further studies on mechanism of bio-control against plant pathogens and plant growth promoting activities of Achromobacter xylosoxidans need to be conformed under in-vivo condition.

Dr. SARANYA DEVI K Dr. saranya devi k

Strategic management - concept of strategy

The strategy is a means of establishing the organisation's purpose in terms of priorities for resource allocation, action programs and long term objectives (Grant 2005). Chandler (1962) defines strategy as determining the primary long-term goals of an organisation, the adoption of courses of action, and the allocation of necessary resources. Besides, the strategy also focuses on allocating resources in relation to the organisation and its environment (Schendel & Hatten 1972). The strategy also pertains to the top management's decisions pertaining to its scope and the future direction. Such strategy covers an action plan on the organisation's future, commitments to specific products, services, and the markets.

Zamzam Abdelazim Zamzam abdelazim

Project management - tesco plc's operation

In this report, Tesco PLC's operation and project management have been fully elaborated on. Tesco PLC is a retail organization that deals with retailing and other related activities in insurance service and retail banking (REUTERS, 2020). Tesco is multinational general merchandise and groceries with headquarters at Welwyn Garden City in England. Based on gross revenue rating, Tesco is the third-largest retailer in the world. Tesco was created by Jack Cohen in 1919 in Hackney, London as a set of markets stalls. Tesco developed and expanded very fast in the whole world and above 100 Tesco shops in the entire Facebook. Tesco has segments in ROI and the UK that is; central Europe (Hungary, Slovakia, and the Czech Republic), the Republic of Ireland, and the United Kingdom which do similar activities to those done in Tesco bank in the United Kingdom (Bedford, 2022). Tesco avails different personal banking packages (services and products) that include personal loans, personal current accounts, and credit card receivables. Tesco's businesses are therefore Tesco Hungary, Tesco UK, Tesco Czech Republic, Tesco Slovakia, Tesco Ireland, Dunnhumby, and Tesco Bank.

Zamzam Abdelazim Zamzam abdelazim

Alpha-numeric analysis of engineers cum arbitrators - numerology

ABSTRACT “Numbers are the highest degree of knowledge. It is knowledge itself.”- Plato “The world is built on the power of numbers.” Pythagoras “Everything around you is numbers.” Shakuntala Devi. The date, we were born on, was not an accident. Each number in our date of birth is connected with certain energies and vibrations. Similarly, each and every letter in our name (first as well as full name) also has particular frequency, energies and vibrations. The combined and correlated energies of numbers and letters of an individual reveal about the past, present and future. The careful study of these universal divine energies can reveal, who you are, why you are here, where are you going and how will you get there. In other words what is your personality, nature, thinking, and what is your future in terms of family career relationships and finances etc. In this study, an attempt has been made to analyze -How certain patterns of name numbers and date of birth related core numbers can emerge as a directional guide for an individual to choose any specific career/profession (by studying the patterns of over 1100+ date of births and names of the Engineers cum Arbitrators).

Jyotsnaa G Bansal Jyotsnaa g bansal

Potential role of hydrogel and its future applications in bioprinting and in-vitro organ development

Abstract: Recent studies on hydrogels have shown them as promising biomaterials for numerous applications involving tissue engineering, drug-screening, drug-delivery, and 3-D bioprinting because they show unique physicochemical properties. The ability of these structures to hold large amounts of water is because of their hydrophilic nature that provides a soft and hydrated environment like natural tissues. This makes them ideal for mimicking the extracellular matrix and supporting cell growth and proliferation. In tissue engineering, hydrogels might be used to create scaffolds that promote cell growth and facilitate tissue regeneration. Hydrogels can also be engineered in such a way that they intimate the mechanical and biochemical in vivo characteristics making them a versatile tool for applications in tissue engineering. Hydrogels are being used in drug screening, as they can be functionalized with different biochemicals in order to match the microenvironment of specific tissues. This allows researchers to study how drugs interact with cells and tissues in-vitro conditions, which can lead to more efficient strategies for drug development. For applications in drug delivery hydrogels are designed to release drugs in a sustainable and controlled way, improving the drug efficacy and reducing the toxicity of drugs. Designing can also be done in a way that they can target specific tissues and cells making them a promising tool for personalized medicine. Hydrogels are being used in 3-D bioprinting, where they serve as bio-inks that can be fabricated into complex structures with high precision. In comparison to conventional technologies, this is a promising technique that allows the construction of complex three-dimensional structures in a sequential manner by a computeraided system. One major challenge in bioprinting is finding such material that is suitable for printing and also satisfies the mechanical strength requisite for tissue engineering applications. That is where hydrogels serve as the most appropriate model and have encouraging or favorable operation potential as cell-affable materials. This technique has revolutionized tissue engineering by allowing researchers to create functional tissues and organoids and spheroids. Overall, hydrogel-based tissue engineering, drug screening, drug delivery, and 3D bioprinting are exciting areas of research with great potential to significantly impact different areas of medicine and biology.

Deepika pal

Controlling the apex in early onset scoliosis through active apex correction (apc) non fusion growth modulating technique, is it a myth?

Study DesignA multicenter retrospective study. ObjectivesTo determine the rate of Apex facet fusion in children with Early Onset Scoliosis treated surgically with the Active Apex Correction (APC) technique. MethodsSeventeen patients were treated with the APC technique as index surgery for Early Onset Scoliosis with more than 1 year of follow-up. A 3D CT scan was done to determine the facet fusion rate in the deformity’s apex controlled with posterior tethering. ResultsThe average follow-up time was 26.4 months (12-56), Average age at index surgery was 81.2 months (30-132), and average number of surgeries done 1.3. Apical vertebrae studied for facet fusion were the 3 vertebrae in the apex in each patient that were subjected to posterior tethering according to the APC technique. In total they were 86 apical vertebrae (172 Facets studied with 86 convex side, 86 concave side). Our observations showed that 29 facet joints were fused (16% of the total facets studied),15 were on the convex, 14 on the concave side (no statistically significant difference). Regarding the facet joint distance in the non-fused facets was 0.99 mm on the convex side and 1.08 mm on the concave side with no statistical significance difference. ConclusionAPC for Early Onset Scoliosis achieves apical growth modulation and control utilizing posterior tethering without inducing fusion. This study demonstrated that APC is an effective non-fusion technique through the low incidence of facet fusion levels at the Apex, limiting the crankshaft phenomena seen in cases with apex control through arthrodesis.

Mohamad  Banat Mohamad banat

Insecticidal activity of castanospermum australe against stored grain pest callosobruchus analis

The butanol fraction of the leaves of Castanospermum australe Cunn. & Fraser., was tested on adult Callosobruchus analis (pulse beetle) for its insecticidal activity by impregnation method at concentrations of 3, 9, 48, 240 and 354 μg / cm2. The result showed that the extract is toxic to Callosobruchus analis and the LD50 was found to be 38 µg/cm2. The insecticidal activity of the butanol fraction of Castanospermum australe leaves against adult Callosobruchus analis was determined by impregnation method in five different concentrations and the result so obtained revealed that the extract is toxic against the test insect (pulse beetle). The mortality was lowest (14 %) at 3 µg/cm2 and highest (96 %) at 354 µg/cm2 (Table). The LD50 by log-log graph was found to be 38 µg/cm2. It may be said that the saponins of this plant could be utilized as a natural insecticide that could be an effective alternative for insect pest management.

Dr. Salman Ahmed Dr. salman ahmed

Libyan mother's awareness of natural products among infants

In Libya, mothers commonly use natural products for their infants. The purpose of this survey was to evaluate the level of awareness of mothers using natural products for their infants, a validated questionnaire-based survey was distributed for mothers in several hospitals, the selected random group included 152 mothers of infants aged from day one birth to one year old, an analysis of the data revealed that 68% of mothers were using natural products and the most predominant age was between 20 - 30 years, 63% were living in Tripoli and 52% were undergraduate level of education. Further statistical analysis was revealed a significant difference for measuring the degree of awareness of all the natural products combined together (p = 0.001) and a similar degree of significant difference to the degree of awareness of each natural product alone (p = 0.001). A correlation coefficient test by Spearman was preformed to evaluate if there is any association between participants’ demographic data and the question which measures the level of mothers’ awareness. The results showed that mothers have no awareness on how to use these natural products and no correlation between the participants’ demographic data and the way the mothers use these natural products, except between the fennel and the education level (p = 0.033, p < 0.05, respectively). In conclusion, mothers have no awareness on how to use natural products, an appropriate attention by health care providers should be given to nursing mothers for herbal use.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

Research capability of teachers: its correlates, determinants and implications for continuing professional development

Recently, research capability has received an overwhelming and remarkable interest among academics and practitioners. This is timely since the Department of Education had institutionalized research and encouraged teachers to engage in it to support evidence-based practice, decision-making, policy, and program development. On these premises, a study was carried out to assess the research capability of public teachers in Malaybalay City, determine its correlates and determinants. It utilized descriptive, correlational, and explanatory designs. It administered survey questionnaires to 92 participants. Data were analyzed using descriptive and inferential statistics. The results revealed that teachers were slightly capable of conducting research and having neutral attitudes toward it, motivated to write research, had a high level of difficulties in research processes, and moderately capable of action planning. They also show evidence of potential in mentoring. Further, mentoring and action planning skills, motivation to write research, attitudes toward research, and the number of studies completed by teachers were the correlates of their research capability at different magnitudes of the relationship. Notably, the research capability of teachers had a low, negative but significant relationship with their age and accumulated years of service. Thus, this capability deteriorates as they age and accumulate years of service. The motivation to write research, the number of studies completed, and age were the determinants of research capability. It was concluded that research capability can be determined and predicted by how motivated teachers are to write research, how productive they are in research, and how young they are when they engage in this rigorous endeavor. The study identified and recommended topics for continuing professional development.

Manuel Caingcoy Manuel caingcoy

Vitamin c and human diseases: an overview

Vitamin C is associated with history of the cause of the ancient hemorrhagic disease scurvy. Vitamin C is an essential nutrient with important antioxidant properties. It is required by the body for normal physiological function. The body cannot synthesize vitamin C, it is present in nature through foods and other natural sources and it exists as a nutritional food supplement. The antioxidant activity of vitamin C protects the body from free radical damage. Vitamin C is essential for the development and maintenance of connective tissues. It is used as therapeutic agent in many diseases and disorders. Vitamin C plays an important role in several metabolic functions, as the conversion of the amino acid, tryptophan, to the neurotransmitter, serotonin, and the conversion of cholesterol to bile acids. Vitamin C supplementation resulted in a significant increase in vitamin C levels in populations; its high intake is associated with positive effects on cardiovascular risk factors. Vitamin C protects the immune system, reduces the severity of allergic reactions and helps to fight infections. It has an important role in bone formation, wound healing and the maintenance of healthy gums. There is profound beneficial effect of vitamin C in respect to human diseases as cancer, atherosclerosis, diabetes, neurodegenerative disease and many metal toxicities. Several vitamin C analogs have been produced as anticancer and antioxidant activity. Vitamin C is useful if it is used as adjuvant therapy for several chronic diseases. Thus, this review summarizes the importance of vitamin C in the body’s physiology and biochemistry, in addition, the different mechanisms that vitamin C is implicated to treat different acute and chronic diseases. Future exploration should pay attention to chronic disease management by vitamin C.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

Management of an anticipated difficult airway due to a vallecular cyst in an adult patient: when surgical airway takes the lead!!

Vallecular cysts, although infrequent in adults, pose a challenge for anesthesiologists in view of the risk of airway obstruction at anesthesia induction or aspiration in case of cyst rupture. The present case is of a 35-year-old male patient who was scheduled for excision of a vallecular cyst. An awake technique was initially decided for nasotracheal intubation using a flexible videolaryngoscope, AmbuscopeTM, after complete topicalization of the airway with local anesthesia. However, anticipating the need for a tracheostomy, the surgical team was prepared, and this was timely chosen as the only viable option following failure to visualize the glottis despite negotiating every possible way around the cyst. This case highlights the successful management of a large vallecular cyst in an adult patient, where failed awake nasotracheal intubation despite optimal preparation necessitated an early, planned tracheostomy. This reiterates the fact that the surgical airway may not be always chosen as the last resort in crisis but also as a timely intervention to prevent an airway catastrophe.

Journal of Scientific Innovations in Anesthesiology Journal of scientific innovations in anesthesiology

A study on work life balance of self employed women entrepreneurs in mangalore city

Increasing presence of women in economic pursuits like entrepreneurship activities is believed to be the result of development policies. This belief ignores the role of socioeconomic factors in the growth and development of women entrepreneurship. Many women entered the world of business and they have become successful entrepreneurs in various business activities. Women entrepreneurs in Dakshina Kannada district have set up business ventures in a range of industries. The study has been conducted to know the extent of problems faced in managing work and life by women entrepreneurs. Majority of the respondents started their business or service to become independent and to meet the financial needs of their family. From the study it has to be found that majority of the women find it difficult to manage their work and family and they are trying to overcome these difficulties by time management and with the help of their family members.

Thara S Shetty Thara s shetty

Recruiting the public relations officer during british colonial malaysia

This is a study on the growth of public relations in Malaysia based on the advertisements placed in the newspapers during the colonial period. Tracing the historical development serves to make a better understanding about the nature of public relations practice. This paper therefore aims at exploring the development of the public relations profession by studying the advertisements placed in the nationwide newspapers, the Straits Times and the Singapore Free Press & Mercantile Advertiser from 1939 which included the early advertisement that contained the phrase “public relations” to 1956 a year before the independence of the Federation of Malaysia. An analysis of the advertisements was made to fully understand the historical development of public relations in Malaya or then Malaysia. The very first advertisement that was identified was on 31 January 1948, which was placed by the Department of Public Relations of the federal government. The British colonial government had placed another four advertisements in 1949 and 1950. A British mining Co. was the first corporation to hire an information & public relations officer in 1956. The results showed some differences and similarities through the analyses of advertisements in the job specification, which included qualification, duties, and salaries. The results revealed that those who had higher education and experience obtained a higher salary. The results also showed that some advertisers companies/ organizations had substituted academic qualifications for working experience) when advertising for their public relations personnel.

Mohammed Fadel Arandas Mohammed fadel arandas

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