A P2P network can be an ad hoc connection- a couple of computers connected via a Universal Serial Bus to transfer files. And these networks are vulnerable to peers. The traditional security techniques are insufficient for P2P networks as they are insecure by their very nature. There’s no centralized server controlling access to shared resources in a P2P network which have unique challenges including identity management of the peers, secure reputation data management, Sybil attacks, and above all, availability of reputation data. The future actions are predicted where peers are encapsulated in its digital reputation, based on the past behaviour of the peer.Thus a peer’s reputation allows it to cooperate and prevent from malicious activities. The cryptographic protocol is coupled with selfcertification and cryptographic mechanisms for identity management and countering Sybil attack.

Dr h shaheen

Background: Although statins are considered safe, they do have side effects with a wide range of hepatic adverse effects. The present study aims to estimate the frequency of liver injury in patients treated with various statins and to describe their clinical characteristics and outcomes. Materials and Methods: We carried out a secondary post hoc analysis of collected data from our previous study entitled “Frequency of Rhabdomyolysis in Patients Treated with Statins in Hamad General Hospital, Qatar.” Results: We identified 10 cases (1.0%) of statin-induced liver injury during the study period. Their mean age was 62±10.09 years, with 6 (60%) males and 4 (40%) females. Of the 10 patients, six patients received rosuvastatin, two patients received atorvastatin, and other two cases received simvastatin. The mean duration between the initiation of statin and the development of liver injury (latency period) was 20.40±6.91 months. Five of our patients were asymptomatic, and liver injury was discovered incidentally during routine testing of the patients during routine follow-up, while four patients developed painless jaundice and one developed muscle pain attributed to rhabdomyolysis. Statins were stopped in all patients. Nine of them were managed on an outpatient basis, while one patient with rhabdomyolysis was admitted. In all patients, other statins were reintroduced after a mean time of 7.4±3 months without recurrence of liver injury. No mortality has been reported. Conclusion: Our study demonstrated that statin-induced liver injury is a rare clinical entity that occurs regardless of the dose and type of statin, with rosuvastatin being the most causative drug. Statin-induced liver injury was asymptomatic and was discovered incidentally in 50% of our cases during routine testing, underscoring the importance of routine follow-up of liver function tests in asymptomatic patients.

Karishma

Investigating school performance and competencies, especially on leadership, received a considerable attention in the past. In fact, there have been multitudes of evidence that leadership can impact school performance, student achievement, or outcome. Also, there was no single measurement of school performance. This study examined the influence of leadership and core behavioral competencies on the school performance of school heads. This was to build a new model of school performance. Using an explanatory research design, it administered a survey questionnaire to 192 randomly chosen school heads from the 37 districts of Department of Education Division of Surigao del Sur. Also, it used data mining for the performance ratings of school heads from the division office. Regression analysis tested three hypothesized models of school performance where leadership and core behavior competencies serve as independent variables. Results showed that leading people was a significant predictor of school performance. Thus, leading people can best explain the school improvement as a proposed model. The results have implications for future research, leadership practice, and theoretical development of school performance model among school heads.

Manuel caingcoy

CoronaVirus’ is a hard hit on both Millennial consumers and marketers. It forced consumers and marketers to do the usual activities of buying and selling differently. Panic buying and herd mentality was widely noticed among millennials. Their unusual buying behavior which reflects behavior during a crisis is highly influenced by environmental stimuli. From this study, it is found that there has been a significant buying behavioral shift of global millennials in emerging markets (BRIC – Brazil, Russia, India, China; CIVETS – Columbia, Indonesia, Vietnam, Egypt, Turkey, South Africa). It is evident that the initial marketing attempts of marketers failed during COVID-19 due to the lack of understanding of the significance of environmental and marketing stimuli in consumers’ purchase decisions. This study brings out the various positive substantial changes brought about through internetization in marketing goods and services to millennial customers during the pandemic. The pandemic enabled a rapid digital revolution in buying and selling using digital/online platforms. The study suggests the application of the Black Box Model by marketers in marketing and selling decisions. The Internet has been the most important tool used by customers and sellers to access what they need. This study is useful to marketers and upcoming entrepreneurs to understand that it is the consumer’s buying behavior that triggers and pushes marketers to sell differently.

Sridevi

Telangana, a rapidly developing state in India, is committed to transforming its higher education landscape to meet the demands of the 21st century. This abstract outlines the key strategies and initiatives being implemented to elevate educational standards and ensure that students receive a world-class learning experience. This paper explores the efforts and strategies implemented to elevate the standards of higher education in Telangana, focusing on the challenges and opportunities encountered in delivering quality education. Over the past decade, Telangana has taken significant steps to enhance its higher education system by improving infrastructure, curriculum, teaching methodologies, and fostering collaborations with national and international institutions. The introduction of state-specific initiatives, such as the Telangana Academy for Skill and Knowledge (TASK), along with reforms in university governance, accreditation processes, and the promotion of research and innovation, has played a crucial role in improving educational outcomes. The paper also delves into the socio-economic impact of these improvements, particularly the increased employability of graduates, their contributions to the local economy, and the role of emerging institutions like Young India Skill University. By addressing both the successes and ongoing challenges, this study aims to provide insights into how quality higher education can be a catalyst for regional development and social mobility in Telangana.

Dr gedam kamalakar

Treatment adherence is a critical component of epilepsy management. Antiepileptic drug side effects affect adherence and may result in the discontinuation of medication. This study aimed to investigate the association between antiepileptic drug side effects and medication adherence among Libyan patients with epilepsy while identifying predictors of adherence. A cross-sectional study was conducted at Tripoli University Hospital involving 200 adult epilepsy patients. Adherence was assessed via a self-report tool dichotomized as adherent/ non-adherent if patients stopped medication due to side effects. Side effects were evaluated using the Side Effects of Antiepileptic Drugs questionnaire. Logistic regression analyzed predictors of adherence, including antiepileptic drug use, therapy regimen, and side-effect profiles, with p<0.05 declared association. The overall adherence rate was 87.0%. Higher adherence was observed in older age groups, 95.8% in patients aged 51-60, 89.4% in married patients, and 91.0% in university-educated patients. Patients on monotherapy and those seizure-free in the preceding month demonstrated better adherence (88.4% and 93.0%, respectively). Valproate users had notably low adherence (52.6%) while carbamazepine and phenytoin users showed higher adherence (89.7% and 91.7%, respectively). Cognitive complaints significantly reduced adherence (76.1% vs. 79.6%), as did aggressive behavior (58.3% adherence). Logistic regression identified two independent predictors: patients on old-generation antiepileptic drugs had 2.7 times higher adherence (AOR=2.702, 95% CI: 1.168-6.249; p=0.02) while cognitive side effects reduced adherence by 86.4% (AOR=0.136, 95% CI: 0.031-0.596; p=0.008). Cognitive side effects predict non-adherence, necessitating routine monitoring. Paradoxically, older antiepileptic drugs correlated with better adherence. Integrating patient-reported metrics and addressing cognitive impacts could optimize epilepsy care, highlighting gaps in side-effect management and advocating personalized strategies in clinical settings.

Mediterranean journal of pharmacy and pharmaceutical sciences

Ambon Bay consists of the inner Ambon Bay (IAB) and the outer Ambon Bay (OAB) and they are separated by the shallow sill (12 m) Galala-Rumah Tiga. The topography of the bay makes it unique and causes the exchange of water mass between those two parts of the bay does not follow the daily tidal cycle. The aim of this study was to analyze the vertical and horizontal temperature and chlorophyll-a distribution in order to know the water circulation in Ambon Bay. This study was carried out during the monsoon, in November 2018. The CTD was used to measure in situ temperature and chlorophyll-a concentration. The data were analyzed by using Surfer and ODV programs. The results show that the temperature of the surface water (0-5 m) of Ambon Bay was 29.2℃. In depth 15-40 m, temperature was different between the IAB (27.7-28.2℃) and OAB (29,2-28.7℃). Chlorophyll-a concentration was found higher in the IAB than in OAB in all depths. In the depth >12 m, chlorophyll-a in the IAB was 1 mg/m3 compared to its concentration in OAB only 0.3 mg/m3. As a conclusion, the sill in Ambon bay causes unique circulation of water mass between IAB and OAB based on the analysis of temperature and chlorophyll-a concentration distribution.

Irma kesaulya

This study aimed at the evaluation of the quality attributes and sensory properties of noodles produced from composite blends of acha, adu, mungbean and moringa oleifera seed. Composite flours of acha, adu, mungbean and moringa oleifera seed were formulated by total replacement of wheat with acha, adu, mungbean and moringa oleifera seed at different graded ratios (B= (55:35:5:5), C= (55:30:10:5, D= (50:30:15:5), E= (50:25:20:5), F= (45:25:25:5) while 100% wheat flour was used as the control (sample A)). The composite flours were used to produce noodles and the noodles subjected to proximate analysis and sensory properties evaluation. Proximate analysis revealed that the noodles contained moisture content of 10.22-13.90%, 2.32-4.48% ash, 10.13-17.90% protein, 1.50-5.71% lipid, 0.48-3.68% crude fibre, 54.33-75.35% carbohydrate and 340.31-355.42Kcal/100 g energy. There was an increase in the moisture, ash, protein, lipid and crude fibre contents with a decrease in carbohydrate and energy contents as the amount of mungbean flour increases. Sensory evaluation scores showed that noodles made with 0% wheat, 55% acha, 35% adu, 5% mungbean and 5% moringa oleifera seed can favourably compare with the control. It is recommended that the beany flavour of mung beans be removed before its addition in the composite blend in order to produce noodles that can be highly accepted.

Okechukwu obed chukwuemeka

Green computing is focusing on reducing the energy consumption, resource usage, carbon dioxide emission. It was found that Last year, Google used about 12.4 terawatt-hours of electricity. Energy consumption in data centers is reduced by decreasing the resource utilization that is by switching off or shifting the computing nodes to sleep mode. But when the servers are being used the energy consumption is minimized by using energy efficient scheduling and optimization techniques.In WNS the sensor nodes are deployed in remote areas, these sensors are powered by battery that decreases the lifetime, therefore by using energy efficient techniques can increase the uptime of the battery-operated devices in WNS. This work studied various energy efficient techniques that minimize energy consumption usage in Data Centers (DC) and the algorithms that increase the uptime of the battery-operated device in (WNS) Wireless Network Sensors.

Dr h shaheen

This article explores how telemedicine, especially with the help of artificial intelligence (AI), is transforming healthcare. It covers its applications in monitoring patients, managing chronic diseases like diabetes, and improving cardiovascular care. The importance of wearable devices and non-invasive blood glucose monitoring is highlighted. The article emphasizes how AI-driven remote patient monitoring can enhance healthcare by providing early intervention, reducing hospitalizations, and offering personalized care.

Dhruvitkumar talati

The utilization of traditional medicine (TM) is prevalent among the general population in Africa; however, its use among individuals with diabetes in the region remains underdocumented. This review aimed to synthesize the available literature to identify the prevalence and predictors of TM use among persons with diabetes in Africa. A systematic search was conducted across multiple databases, including MEDLINE, Embase, CINAHL, and AMED, covering studies published from 2000 to April 2023. Of 1560 records identified, 24 articles met the inclusion criteria. The prevalence of TM use varied significantly, ranging from 12.4% to 77.1%, with a median prevalence of 50%. TM was commonly used concurrently with conventional medicine (CM) (35.4–88.4%), with a majority (63.8–91.3%) not disclosing TM use to healthcare providers. Female gender, long diabetes duration, use of oral antiglycaemic medication and family history of diabetes emerged as the most common factors that predicted the use of TM. This review highlights the widespread use of TM among individuals with diabetes in Africa, often in conjunction with CM. The high prevalence of undisclosed TM use emphasizes the urgent need for healthcare providers to actively inquire about TM use during clinical consultations to address potential herb–drug interactions and adverse effects.

Emmanuel ekpor

Kegiatan keagamaan merupakan kegiatan yang amat penting di MI Negeri 3 Jember, mengingat masih banyak peserta didik yang membutuhkan bimbingan guru untuk memiliki karakter yang sesuai dengan tuntunan Islam, di zaman teknologi initidak bisa dipungkiri bahwa anak-anak zaman sekarang sudah mengenal yang namanya internet. Maka dari itu pendampingan orang tua dan guru sangat dibutuhkan dalam perkembangan anak-anaknya. Salah satu pendidikan yang diajarkan guru kepada peserta didiknya sejak dini adalah pengajaran tentang al-Qur’an.Oleh karena itu darus keliling (darling) merupakan kegiatan yang tepat dalam proses membelajarkan al-Qur’an dalam rangka menanamkan karakter religius kepada peserta didik. Fokus penelitian yang dikaji adalah: Bagaimana peran guru sebagai pembimbing dalam menanamkan karakter religius peserta didik melalui kegitan ekstrakurikuler darus keliling (darling) di MI Negeri 3 Jember tahun 2019? Penelitian ini memperoleh kesimpulan: Peran guru sebagai pembimbing dalam menanamkan karakter religius peserta didik melalui kegiatan ekstrakurikuler darus keliling di MI Negeri 3 Jember dalam hal ini adalah guru yang senantiasa membimbing anak-anak anggota darling untuk belajar al-Qur’an. Darling ini adalah sebuah wadah yang diberikan oleh guru untuk mengembangkan potensi peserta didik. Karakter religius pun terbentuk yakni sikap patuh dalam menjalankan agama Islam, misalnya membaca al-Qur’an. keliling di MI Negeri 3 Jember dalam hal ini menggunakan instrumen penilaian yang memiliki 3 aspekpenilaian yakni aktif, kurang aktif dan tidak aktif.

Educare: journal of primary education

This article presents the relevance of Mahatma Gandhi’s philosophy toward the Social Work Profession in India. It is a review article prepared with secondary data available in books and journal articles. Mahatma Gandhi was a prominent leader of the Indian independence movement in British-ruled India. His principles viz. Non-violence, Satyagraha, Swadesi, Sarvodaya and Democratic leadership led Indians to strive to bring independence to India. He had launched the freedom struggle movements viz. Dandi Salt March, Quit India and Non-Cooperation Movement for Independence. Gandhi found a few disparities in India and developed a concept called constructive programme with the points of conflicts between different religious groups, castes, untouchability, fear arising out of ignorance, economic disparities, decaying condition of our villages, the plight of Adivasis, Kisans and the labourers, and the position of women, etc. Gandhiji motivated his followers, and freedom fighters to work on the said disparities. These constructive programme points are very relevant to the social work profession and nowadays many social workers are working on these programmes. This article presents how Gandhian principles like Nonviolence, Satyagraha, Swadesi, and Sarvodaya are relevant to the social work profession. Gandhiji Principles such as seeking truth through service to the poor and needy, individual self-development and self-reliance, nonviolence social action and material simplicity are very related to the code of ethics of professional social workers. The study suggested that professional social workers should practice the principles of Mahatma Gandhi in their interventions. The associations of professional social workers should adopt the Gandhiji principles and include them in the social work curriculum

Vijaya abraham

Sheath blight and Sheath rot of rice caused by Rhizoctonia solani and Sarocladium oryzae is an economically important disease causing rigorous yield losses. Biological control of the disease using plant growth promoting rhizobacteria (PGPR) is a potential substitute to the presently available chemical control methods. The present investigation was aimed to study the plant growth promoting (PGP) activity and antagonistic activity of two rhizobacteria Pseudomonas fluorescence and Rhizobium sp., isolated from rhizosphere area of rice, against two major rice pathogens. In the present work IAA (Indole acetic acid production) was found maximum amount in Pseudomonas fluorescence (30 mg / ml) and trace amount in Rhizobium sp. Maximum amount of Siderophore production was noticed in both isolates. Pseudomonas fluorescence showed positive result for the HCN production but Rhizobium sp., was found to be negative and both bacterial isolates solubilized phosphate in very effective manner. Both rhizobacteria were found to produce ammonia and catalase. The cross streak studies revealed that the complete inhibition of mycelia growth of Rhizotonia solani (85%) and partial inhibition of Sarocladium oryzae (45%) against two rhizobacteria. Antifungal compound extracted from both rhizobacteria were found to exhibit maximum antagonism against rice pathogens. This result concluded that both PGPR’s can be used as best bio-control agent against rice pathogens instead of hazards chemicals.

Dr. saranya devi k

Tobacco smoking negatively affects the quality of saliva and affects many biological parameters including salivary α-amylase enzyme activity. Salivary α-amylase enzyme is essential for the catabolism of carbohydrates. Forty- five healthy male volunteers aged between 18 and 69 years (40.0 ± 15.0) were divided into two groups, namely, the control group (n = 21) and the cigarette smoker group (n = 24). The effect of smoking on salivary α-amylase enzyme activity depends on the number of smoked cigarettes per day and the type of cigarettes as well as the period for how long the person smoking tobacco cigarettes was investigated. Different methods were used to analyze the activity of salivary α-amylase enzyme including the dinitrosalicylic acid method (standard colorimetric method). The results showed a significant increase (P < 0.05) in salivary α-amylase activity in Libyan smokers compared to the non-smokers in the morning and night, also, the findings showed a significant decline in salivary α-amylase activity during the increasing smoking period. The activity of salivary α-amylase in the young age smokers group increases in morning and night compared to the non-smokers group. There is no change in the activity of salivary α-amylase in the middle and older adult groups in the morning and night compared to young smokers group. In conclusion, smoking for a long period time more than 20 cigarettes per day decreases the activity of salivary α-amylase in Libyan subjects.

Mediterranean journal of pharmacy and pharmaceutical sciences

This paper found that 35% of Adivasis have health problems, and 73% said that they are getting treatment with RMP. 87% have toilet facility and more than 12% still defecate openly. 18.3% said that they faced different problems at open defecation, and 50% of women not using sanitary napkins. Nearly 90% of respondents wash their hands after toilets and coming from outside of the home. Ten per cent of respondents said that they do not have an awareness of sanitation. Therefore, the study confirmed that the sanitation facilities considerably made the women's dignity and quality of life better in the study area. Moreover, four case studies also focused on open defecation problems in the study area.

B suresh lal

Aerva lanata species belonging to Amaranthaceae family (a.k.a mountain knot grass/Gorakha Ganga is a perennial shrub. It is self-pollinating, bisexual plant having globose like structure has various phytochemical constituents. Among the 28 species of Aerva, medicinal properties are likely to be present in Aerva lanata, Javanica and Persica varieties. Traditionally it was used in treating cough, dysuria, hemiplegic migraine and kidney related disorders. Flavonoid glycosides such as Kaempferol, Isorhamnetin, quercetin, flavanone are major phytoconstituents and minor constituents are apigenin, narcissin, ferulic acid, syringic acid and vanillic acid. Alkaloid glycoside includes Ervine, aervine etc. Aerva lanata has much more beneficial activities like demulcent, diuretic, ulcer wounds, rheumatism, Anti-malarial. Pharmacological studies included that aerva species has beneficial properties of antimicrobial, anti-urolithiasis, antiulcer, anti-asthmatic, acute kidney injury, anti-diarrheal activity, antioxidant, antihyperglycemic, hypolipidemic and antiulcer. Aerva lanata has promising role in the treatment of various diseases and metabolic disorders due to its higher antioxidant effect and other such constituents thereby providing better healthcare. Various such constituents are to be analyzed properly and to ensure that it was suffice to exhibit the pharmacological activity. Analytical methods are to be used promptly to find various concentration of substances present in the alcoholic extract of Aerva lanata plant.

Ankul singh

Abstract: Objective: To evaluate the Antiparkinson activity of Allium sativum in Haloperidol induced Parkinson‟s disease in mice. Method: Parkinson‟s disease was induced by administering haloperidol (2.0 mg/kg i.p.) Daily for a week. The mice were divided into 5 group (n=6). Group II received haloperidol (2mg/kg body weight).Group III received combination of levodopa and carbidopa (100mg+ 10mg/kg by i.p along with haloperidol) and Group IV and V received Allium sativum extract (200 and 400mg/kg by p.o), respectively for 7 days along with haloperidol. To evaluate the antiparkinson effect of Allium sativum, catalepsy bar test, rotarod test, hang test and horizontal bar test were used. One way ANOVA was used to test statistical significance followed by Bonferroni multiple comparison tests .Results: Allium sativum extract (200 and 400mg/kg by p.o) was found to decrease the duration of catalepsy significantly (P<0.001) in catalepsy bar test as compared to haloperidol group, and significantly increases (P<0.001) fall off time in, rotarod test, hang test and horizontal bar test respectively as compared to haloperidol group. Conclusion: The result of the present study conclusively shows the Antiparkinson‟s activity of Allium sativum in haloperidol induced Parkinson‟s disease in mice.

Zeenath banu

The Gantt chart below presents the activities that must be done to complete the project related to the creation of the company's management information system. The total project duration is three months, and it can be seen that the timeline reflects this target.

Zamzam abdelazim

Cardiovascular drugs constitute one of the largest and most widely used among other diseases and cardiovascular drug market has largely been exploded . Although these drugs have the potential to significantly improve the treatment of various cardiac diseases. They are potent agents with potential for serious adverse effects, toxicity and drug interactions. Newer agents are considerably costly than older drugs and, therefore, cost-effective strategies must be developed. Thrombolytics are pharmacological agents come from bacterial origin as streptokinase and staphylokinase or from human origin as urokinase or t-PA. Thrombolytics are used to restore blood flow to infracted artery quickly. Only streptokinase, alteplase, reteplase and tenecteplase are approved by US-FDA for treatment of ST-elevation myocardial infraction (ST-EMI) [3]. This reopens blood vessels after their occlusion and prevents tissue necrosis. Although, the safe and effective use of each of these drugs requires a thorough understanding of appropriate patient selection, drug timing, dosing regimens and monitoring parameters. The greatest benefit to risk ratio for specific drugs is seen in certain subsets of patients the complexities of cardiovascular drug therapy illustrate the need for an in depth current knowledge of clinical trial evidence.

Mediterranean journal of pharmacy and pharmaceutical sciences