Ageing is an inevitable phenomenon. Similar to other organs, skin is also subject to an intrinsic ageing process. Additionally, skin ageing is also influenced by various environmental factors. Existing conventional formulations have limited efficacy because skin serves as a rate limiting barrier for percutaneous absorption of drugs. This has led to the evolution of various novel drug delivery systems. Among these liposomes have received considerable attention due to the numerous advantages they offer. Liposomes, submicroscopic spherical vesicles, were discovered in 1960’s. Since then, they have gained popularity as potential carriers for drugs, diagnostics, nutrients, vaccines and other bioactive agents. Liposomes find applications in pharmaceutical, cosmetics and other industrial fields. Various topical actives that have been found to be efficacious in delaying the signs of ageing have been formulated as liposomes resulting in enhanced delivery, biocompatibility, and reduced toxicity. This review focusses on therapeutic use of liposomes in skin ageing.

Aparajita varshney

BACKGROUND AND OBJECTIVES: Fixed-bed column has been considered an industrially feasible technique for phosphate removal from water. Besides the adsorption capacity, the effectiveness of an adsorbent is also determined by its reusability efficiency. In this study, phosphate removal by a synthesized amorphous zirconium (hydr)oxide/MgFe layered double hydroxides composite in a fixed-bed column system was examined. METHODS: The effects of flow rate, bed height, phosphate concentration, solution pH, and adsorbent particle size on the phosphate adsorption ability were examined through a series of continuous adsorption experiments. The appropriate breakthrough curve models, phosphate adsorption from real anaerobic sludge and synthetic seawater, column regeneration and reusability, and adsorption mechanism were also investigated for practical application feasibility. FINDINGS: The results showed that the increased bed height and phosphate concentration, and reduced flow rate, pH, and adsorbent particle size were found to increase the column adsorption capacity. The optimum adsorption capacity of 25.15 mg-P/g was obtained at pH 4. The coexistence of seawater ions had a positive effect on the phosphate adsorption capacity of the composite. Nearly complete phosphate desorption, with a desorption efficiency of 91.7%, could be effectively achieved by 0.1 N NaOH for an hour. Moreover, the initial adsorption capacity was maintained at approximately 83% even after eight adsorption-desorption cycles, indicating that the composite is economically feasible. The high phosphate adsorption capacity of the composite involves three main adsorption mechanisms, which are electrostatic attraction, inner-sphere complexation, and anion exchange, where the amorphous zirconium hydr(oxide) on the surface of the layered double hydroxides likely increased the number of active binding sites and surface area for adsorption. CONCLUSION: The amorphous zirconium (hydr)oxide/MgFe layered double hydroxides composite, with its high adsorption capacity and superior reusability, has the potential to be utilized as an adsorbent for phosphorus removal in practical wastewater treatment. This study provides insights into the design of amorphous zirconium (hydr)oxide/MgFe layered double hydroxides composite for phosphorus removal and recovery in a practical system.

Professor j. nouri

Internship activities are carried out in universities to introduce the working world to students in the future. This is important to be examined, especially in terms of the effectiveness of the program that has been implemented. By conducting a survey of students who have undergone the internship process, a clearer picture can be obtained of overall student satisfaction in response to the placement process during the internship. There are five factors emerge from the data analysis, namely interpersonal skills, work environment, culture, challenges, and benefit.

L

The control of highly pathogenic avian influenza (HPAI) in Nigeria from inception is predicated on effective biosecurity by stamping out policy but outbreaks of the disease continued to re-occur with altered clinico-pathologic manifestations. This study undertook the qualitative assessment of the clinico- pathological features of HPAI H5N1 during the 2021/2022 outbreaks in commercial poultry and peri-domestic birds in northern Nigeria. A total of 22 commercial poultry farms with 53,932 laying chickens and 3 households with 120 backyard broiler chickens, 18 indigenous chickens, 10 peafowls and 9 geese were investigated for HPAI. The clinico-pathologic manifestations observed in commercial poultry were subtle compared to previous presentations of the disease except in the peafowls, geese, broilers and indigenous chickens. The interspecies mortality rates significantly varied from 1.6% to 19.6% for laying chickens and 33.3% to 100% for broilers, indigenous chickens, geese and peafowls. Based on the history of sudden and high mortality, clinical signs and post mortem lesions observed, three diseases; HPAI, very virulent Newcastle disease and fowl cholera were drawn out as differential diagnoses. However, a tentative diagnosis of HPAI was made and samples were sent to the National Veterinary Research Institute, Vom, Plateau State, Nigeria for confirmatory diagnosis. Results of the laboratory tests conducted on the samples using one step flu A screening and duplex real time RT-PCR and virus isolation in embryonated chicken eggs confirmed HPAI H5N1 in twenty-five farms. It is concluded that the continuous though, irregular outbreaks of HPAI and emerging clinico-pathologic manifestations are pointers to failure of control and that the disease may become endemic. It is recommended that government should review its policy on the control of HPAI to include the adoption of zoned vaccination with close monitoring.

Bitrus inuwa

eveloping automated systems with a reasonable cost for long-term care for elders is a promising research direction. Such smart systems are based on realizing activities of daily living (ADLs) to enable aging in place while preserving the quality of life of all inhabitants in smart homes. One of the research directions is based on localizing items used by elders to monitor their activities with fine-grained details of the progress. In this paper, we shed the light on this issue by presenting an approach for localizing items in smart homes. The presented method is based on applying machine learning algorithms to Radio Frequency IDentification (RFID) tags readings. Our approach achieves the required task through two stages. The first stage detects in which room the selected object is located. Then, the second one determines the exact position of the selected object inside the detected room. Additionally, we present an efficient approach based on gradient boosted decision trees for detecting the location of the selected object in a real-world smart home. Moreover, we employ some techniques of over- and under- sampling with data clustering for improving the performance of the presented techniques. Many experiments are conducted in this work to evaluate the performance of the presented approach for localizing objects in a real smart home. The results of the experiments have shown that our approach provides remarkable performance.

Shadi abudalfa

Since 2006, multiple outbreaks of avian influenza (AI) have been reported in Nigeria involving different subtypes. Surveillance and molecular epidemiology have revealed the vital role of live bird markets (LBMs) in the dissemination of AI virus to commercial poultry farms. To better understand the ecology and epidemiology of AI in Nigeria, we performed whole-genome sequencing of nineteen H9N2 viruses recovered, from apparently healthy poultry species, during active surveillance conducted in nine LBMs across Nigeria in 2019. Analyses of the HA gene segment of these viruses showed that the H9N2 strains belong to the G1 lineage, which has zoonotic potential, and are clustered with contemporary H9N2 identified in Africa between 2016 and 2020. We observed two distinct clusters of H9N2 viruses in Nigeria, suggesting different introductions into the country. In view of the zoonotic potential of H9N2 and the co-circulation of multiple subtypes of AI virus in Nigeria, continuous monitoring of the LBMs across the country and molecular characterization of AIVs identified is advocated to mitigate economic losses and public health threats.

Bitrus inuwa

The main focus of this paper is to examine the relationship between insecurity in Nigeria and how traditional institutions such as traditional monarchical system can be used as veritable tool to curtail increasing insecurity in a democratic system such as Nigeria. The pervasive nature of insecurity,though,not an entirely Nigerian problem, has been trending of late, andhence, become a huge source of worry for scholars,experts,public commentators and the international community at large.The menace of insecurity finds expression in wanton killings, kidnapping,farmers-herders conflicts, rape, communal clashes, militia activities, ethnic secessionist agitations and many other strands of violence. The multiplier effects of all these challenges have been very devastating in terms of the recent attacks witnessed all over the country in recent times. This study observes that most of the people engaged in some of these atrocities might be well known to traditional rulers in the communities where they come from. This is because traditional rulers are closest to the people. The work is an exploratory study and relies solely on literature and works of experts in the broader field of security studies for investigation. The paper sums up a conclusion and recommends that there is a need for the adoption of both vertical and horizontal approaches to tackle the menace of insecurity, particularly, using the instrumentality of traditional institutions as a point of departure.

Canice erunke

Adolescence is considered as a crucial stage for emotional development. It is also seen as a time of hyper-emotionality, emotional conflict, and volatile mood states. Given that adolescents lack skills for emotional management, emotional distress during these years can hamper their immediate growth and adversely affect their transition to the next stage of life. Interventions that promote positive emotional development during adolescence are the need of the hour. Keeping this in focus, the present study investigated the Effect of Life Skills Training on Adolescent boys and girls with high Emotional Distress. The study used pre- and post-test experimental design with a control group to examine the stated objectives. 160 adolescent boys and girls (n=80), with a mean age of 16.44 years, were selected for the study using Positive and Negative Affect Schedule. Of these, 80 in the experimental group (boys=40, girls=40) were trained in life skills. Descriptive statistics, independent sample ttest and repeated measures of ANOVA were used to analyze obtained results. Major findings of the study indicate that Life Skills training has significant effect in reducing emotional distress and improving emotional health in adolescents. And the significance of it was found to be higher in girls compared to boys.

Hita claudia rao

Gastrointestinal parasites constitute a serious problem to poultry production in Africa. But often times they are usually ignored by the majority of farmers. Whereas, it is one of the major leading causes of ill-health and high mortality rates in the poultry industry. This study was conducted to determine the prevalence of gastrointestinal parasites of chicken slaughtered at the Jalingo market. A total of 500 gastrointestinal tracts of local chicken comprising of 250 from males and 250 from females were collected from the poultry slaughtering and dressing section of the Jalingo market, and screened for gastrointestinal helminths using the saturated sodium chloride floatation techniques. An overall prevalence of 28.6% (143/500) was recorded with a prevalence of 16.8% (84/500) in males and 11.8% (59/500) females. Nine different species parasites comprising five nematodes and four cestodes, were recorded. Nematodes were the most predominant intestinal parasite with a prevalence rate of 89 (62.2%). And Ascaridia galli 45 (50.5%) was found to be the most prevalent nematode. Other nematodes observed were Capillaria annulata 13.4% (12/89), Heterakis gallinarum 2.2% (2/89), Strongyloides avium 32.5% (29/89), and Syngamus trachea 1.1% (1/89) having the lowest prevalence. Railliatina tetragona 57.4% (31/143) was the most prevalent cestode recorded. Other Cestodes were Hymenolepis carioca 27.7% (15/54), Raillietina cesticellus 12.9% (7/54), and Davainea proglottina 1.8% (1/54). No trematode was recorded in this study. This study showed that nematodes and cestodes were the common helminth parasites in local chicken. There is therefore the need for educating the farmers on the impact of gastrointestinal parasite infection in chicken and the need to institute good management practices so as to reduce their effects on productivity. Sex of the chicken had no statistically significant difference (X2 = 6.12, df = 1; P > 0.05) on the prevalence of helminths.

Bitrus inuwa

Melilotus officinalis (L.) Pallas. is used traditionally to treat hypertension and chronic venous insufficiency. The high prevalence of hypertension and the side effects of antihypertensive drugs potentiate us to evaluate Melilotus officinalis. The hypotensive effect of Melilotus officinalis butanol fraction (MOBF) was investigated in anaesthetised normotensive rats. The doses of 60, 80 and 100 mg/kg, i.v., produced a significant (P <0.05) decrease in blood pressure. The statistically non substantial reduction in blood pressure was shown by 20 and 40 mg/kg, i.v. These results suggest that Melilotus officinalis exhibited a hypotensive effect in normotensive rats. However, further evaluation of compound-related activity is required.

Dr. salman ahmed

A new feature generates customer delight by using modern computer vision techniques to drive new search paradigms through visual discovery.

Senthilkumar gopal

The purpose of this study is to look at development trends and patterns of structural change in India's rural and labour markets. The rural labour strength have been moving from agricultural sector to non-agricultural sector for a living, after a long period of change (due to pain and growth-induced motives). Although the manufacturing sector lags, the building industry is a significant growing sector that employs rural people. Some improvements in rural areas have been made since the implementation of the MGNREGA rural employment development programme, but it has its own set of problems that experts are discussing. Furthermore, the rural labour market is plagued by high unemployment as a result of both the agricultural and non-farm sectors' failure to absorb rural employees. Nonetheless, the continuing COVID-19 epidemic has worsened its situation by causing a job-loss catastrophe. The rural labour market's future will become more unclear as a consequence of Covid pandemic-induced opposite migration of city workers to their villages, which has worsened food security and poverty issues in rural regions.

Dr. amarjeet singh

Background: Hypertension (HTN) has emerged as a significant public health challenge and a leading cause of mortality and morbidity in developing countries like Bangladesh. Objective: This study aimed to assess the prevalence of hypertension and its associated risk factors among resi dents of Dhaka, the capital of Bangladesh, during the COVID-19 pandemic. Methods: A cross-sectional study was conducted using a multistage random sampling technique to select 305 individuals from Khilkhet Thana in Dhaka North City Corporation. Data were collected through direct surveys using a modified version of the WHO STEPS questionnaire and analyzed using SPSS version 22 software. Findings: The study identified a 34.4 % prevalence of HTN among the participants, with 46.2 % of hypertensive individuals being under 40 years of age. Of the 105 hypertensive individuals, 65 % were newly diagnosed during the study, and 11 previously diagnosed individuals were not on any medication. A significant association (P < 0.001) was observed between the prevalence of HTN and inadequate intake of fruits (OR = 3.129, 95 % CI = 1.912–5.122, χ2 = 21.328), insufficient vegetables consumption (OR = 2.199, 95 % CI = 1.356–3.565, χ2 = 10.373), high intake of fatty foods (OR = 2.387, 95 % CI = 1.465–3.890, χ2 = 12.454), and excessive salt consumption (OR = 2.771, 95 % CI = 1.677–4.579, χ2 = 16.310). Additionally, the prevalence of HTN was notably higher among overweight (46.70 %) and at-risk (22.90 %) individuals, based on Body Mass Index (BMI) and waist-to-hip ratio (WHR), respectively. The study also found significant correlations (P < 0.001) between HTN and factors such as smoking (OR = 2.824, 95 % CI = 1.601–4.980, χ2 = 13.432), kidney disease (OR = 7.534, 95 % CI = 2.694–21.070, χ2 = 19.282), general stress (OR = 3.692, 95 % CI = 2.179–6.255, χ2 = 24.896), COVID-19 related stress (OR = 3.511, 95 % CI = 2.116–5.826, χ2 = 24.712) and sleeping pattern (OR = 5.798, 95 % CI = 3.404–9.875, χ2 = 45.724). Conclusions: The high prevalence of HTN, particularly among younger individuals during the COVID-19 pandemic, highlights the urgent need for nationwide surveys, surveillance, and clinical research to accurately depict the true burden of HTN in Bangladesh.

Arafat hassan razon

Background: There is great promise for improving nutrition and health thanks to phytonutrients' antioxidant qualities and health advantages. Their capacity to combat oxidative stress and associated illnesses emphasizes the importance of precisely evaluating their antioxidant characteristics. Objective: This study concludes by providing a comprehensive and critical critique of the current approaches to measure the antioxidant activity of phytonutrients. It dives into the fundamentals, benefits, drawbacks, and most recent developments of commonly used antioxidant assays, giving the reader a comprehensive grasp of the topic. This recapitulation of the review's goal in the end reinforces the reader's primary takeaway. Methods: Research on several antioxidant tests, such as FRAP, ORAC, DPPH, and ABTS, is consolidated in this review. It looks at each assay's performance traits, technological advances, and techniques. The review also assesses the incorporation of many assays to thoroughly examine phytonutrient potency and its uses in the food industry and nutritional science. Results: The review shows how antioxidant tests have advanced significantly, improving sensitivity, accuracy, and physiological relevance. It demonstrates how these tests can be used practically to guarantee food quality, create supplements, and offer nutritional advice. The paper also lists the difficulties today, including the intricacy of antioxidant mechanisms, test variability, and the requirement for assay standardization. The practical value of the research is emphasized by highlighting the significance of antioxidant tests for quality assurance, adulteration detection, and shelf life extension in the food business. Discussion: Scientists, doctors, and business experts interested in evaluating and applying phytonutrients will find this review helpful. It emphasizes how crucial it is to improve antioxidant testing to ascertain the possible health advantages and therapeutic uses of phytonutrients. The review highlights the need for increased test sensitivity, accuracy, and relevance while discussing the benefits and drawbacks of the available techniques. It draws attention to the importance of strong and trustworthy antioxidant tests to maximize the use of phytonutrients in food quality control and pharmaceutical research. Prospects: Future directions seek to address the challenges discovered through the development of multidisciplinary research and testing technologies. Novel approaches will advance our knowledge of phytonutrient potency and aid in developing medicines and nutraceuticals. This study highlights the significance of trustworthy assays for understanding and utilizing phytonutrients, providing academics and professionals in the business with vital insights.

Dr. salman ahmed

Background: This study was conducted to determine the level of the public knowledge, attitudes and practices related to common eye diseases in the southern Indian population. Methods: A cross sectional population-based survey used a semi structured questionnaire on awareness, knowledge, attitude and practices related to eye diseases. Stratified multistage cluster random sampling method was used with a sample size of 867 adults >16 years based on, estimated awareness of cataract 70%, assuming an expected rate of 85%, design effect of 1.5, margin of error 4% with 95% confidence interval with 25% from urban areas and 75% from rural areas. A pilot study was conducted to validate the questions used in the main study. SPSS (version 19) used for analysis. Results: A total of 782/867 (90.1%) subjects participated in the survey, with females 47.4%. Awareness of major eye diseases for cataract 81.5%, glaucoma 47.8%, refractive error 74.3%, squint 89.0%, diabetic retinopathy 65.0% and age-related macular degeneration 36.7% respectively. 41.8% subjects reported wearing glasses either for distance, near or for both. Of the 777 subjects only 294 people underwent an eye examination by an ophthalmologist in the last two years (37.8%). 57.5% subjects had knowledge of the nearest eye care facility within five kilometers of their residence. Electronic media were the major source of information on eye health. Conclusions: Though the awareness levels of common eye diseases were quite high, the knowledge of cataract (10.4%) was poor. There is a need to increase the level of awareness for eye diseases like glaucoma and age-related macular degeneration.

Srinivasa reddy pallerla

The present study shows the pharmacognostic and phytochemical studies on the flowers of Cordia sebestena. L. belongs to the family Boraginaceae. C. sebestena L. is found primarily in tropical and subtropical regions of the American, Asian and African continents. Though it is an essential plant, no pharmacognostic work has been found on its parts, such as flowers. Various organoleptic characters were recorded by macroscopic study. A microscopic study of the flowers was also conducted, which shows the presence of fibres, calcium oxalate crystals and multiple types of trichomes, along with fluorescence analysis. The present study also deals with the Fourier transform infrared spectroscopic analysis of C. sebestena L. FT-IR spectra revealed the presence of C-H, C=C, C-N, C-O and aromatic groups. The chemical composition of the hexane extract of the flowers of C. sebestena L. was detected through GC-MS, and the spectrum achieved through GC-MS was correlated with the database of the National Institute of Standards and Technology (NIST) which comprise more than 62000 outlines of the mass spectrum. GC-MS analysis of n-hexane extract showed the existence of Retinoic acid, lupeol, β-sitosterol, stigmasterol, and hexadecanoic acid, along with fatty acids, esters, alkaloids and alcohols. These pharmacognostic and phytochemical studies can be valuable in providing reliable proof of the quality of the plant, which can benefit health professionals and herbal medicine manufacturers.

Dr. salman ahmed

Inguinal hernia repair is one of the most common procedures performed in general surgery. Approximately 20 million hernia surgeries are performed every year worldwide. Conventionally, hernial repair is carried out with the open Lichtenstein technique; however, laparoscopic and robotic inguinal hernia repairs have been developed as a minimally invasive alternative to the classic Lichtenstein repair. The prosthetic mesh can be placed by totally extraperitoneal and transabdominal pre-peritoneal approaches. Choosing the best technique for repairing an inguinal hernia is a challenge because the available data are contradictory. However, a growing number of studies have claimed that robotic-assisted hernia repair is not only feasible and safe, but it is associated with outcomes that are comparable to those obtained with laparoscopy and open surgery, including shorter hospital stay, and fewer complications. The aim of the review article is to provide an overview of the current practice of inguinal hernia repair, with a focus on the advances in robotic-assisted inguinal hernia repair, as well as the advantages and disadvantages of this surgical procedure compared to the laparoscopic technique in view of the current reports in the literature.

Karishma

Urolithiasis has been a common problem for centuries and has a high recurrence. This review aims to provide comprehensive information about traditionally used antiurolithiatic plants and their scientifically proven pharmacological activities like analgesic, anti-inflammatory, antioxidant, astringent, demulcent, diuretic, litholytic, lithotriptic, antiurolithiatic, antispasmodic, ACE inhibition and Phospholipase A2 inhibition as a plausible mechanism of action. A total of 503 species, 365 genera and 119 families were cited for treating kidney stones. The most cited families are Asteraceae (41), Fabaceae (34), Lamiaceae (26), Apiaceae (21), Rosaceae (19) and Poaceae (16). The most commonly used plant parts are root and rhizome (25%), mode of preparation decoction (62%), and oral administration route in all cases. This review will provide the opportunities for the future research and development of new natural antiurolithiatic compounds.

Dr. salman ahmed

Three species of arbuscular mycorrhizal fungi (Glomus fasiculatum, Glomus mossae and Acaulispora laevis) were used as bio-agents to manage black bundle disease of maize caused by C.acremonium. The results revealed that colonization of arbuscular mycorrhizal fungi in root system of the host reduce the percentage of disease incidenceconsiderably.In the pots inoculated with G. fasiculatum no disease incidence (0.0%) was recorded whereas, in the pots inoculated with A. leavis and G. mossae 16.66 % of disease incidence was recorded and the pots treated with pathogen shows 66.66% of disease incidence compare to control. Among the three bio-agents, Glomus fasiculatumproved to be more effective in managing the disease followed by G.mossae and A. laevis. In addition, all the three AM fungi enhanced the plant growth when they are used alone as inoculum as compared to dual inoculation with the C. acremonium and overall control. This clearly suggests that, AM fungi if used, can serve dual purpose. It can be used as bio-control agent as it shows negative antagonistic interaction soil borne plant pathogens and used as growth promoter because of the ability to supply macro and micro nutrients to the host plants.

Veerabhadraswamy al

Along with computer technology, the demand of digital image processing is too high and it is used massively in every sector like organization, business, medical etc. Image segmentation enables us to analyze any given image in order to extract information from the image. There are numerous algorithm and techniques have been industrialized in the field of image segmentation. Segmentation has become one of the prominent tasks in machine vision. Machine vision enables the machine to vision the real world problems like human does and also act accordingly to solve the problem so it is utmost important to come up with the techniques that can be applied for the image segmentations. Invention of modern segmentation methods like instance, semantic and panoptic segmentation have advances the concept of machine vision. This paper focuses on the various methods of image segmentation along with its advantages and disadvantages.

Manoj kumar pandey