Analgesic activity of luffa cylindrica

The analgesic activity Of the crude hexane and ethanol extracts of the leaves and male flowers of Luffa cylindrica (L.) Roem., (sponge gourds) was carried out at dose of 500 mg /kg b.w., (p.o.) in mechanically induced pain in rats by using analgesy-meter. These extracts produced significant analgesic effect results of the present study revealed the analgesic properties of the leaves and male flowers of Luffa cylindrica.

Dr. Salman Ahmed Dr. salman ahmed

Linking ontology, epistemology and research methodology

The purpose of this paper is to offer insights that can help researchers to link ontology, epistemology and research methodology. This paper outlines the links among ontology, epistemology and research methodology by exploring ontological, epistemological and methodological perspectives in the research. It discusses how ontological and epistemological issues influence research methodology by providing a clear understanding of different research methodologies based on ontology and epistemology. Furthermore, attention is given to research aspects such as the elements of the research process, research philosophy, research approach, research strategy, the choice of method, and research design

Mukhles m. al-ababneh

Pheochromocytoma in pregnancy: a case report and updated management review

Pheochromocytoma is a catecholamine-producing neuroendocrine tumor leading to hypertensive crises in untreated patients. Presentation in pregnancy can mimic gestational hypertension or pre-eclampsia. Physicians need to keep a high index of suspicion to have timely diagnosis and management of pheochromocytoma during pregnancy. We report a 27-year-old female who was diagnosed with pheochromocytoma at 18 weeks of gestation and she underwent laparoscopic adrenalectomy at 22 weeks of gestation with a good pregnancy outcome and with no recurrence over 8 years of follow-up.

Karishma Karishma

The prevalence of and risk factors for stroke among type 2 diabetes mellitus patients in qatar: a hospital-based study

Background and Objectives: The complications of type 2 diabetes mellitus (T2DM) can occur in some organs, such as the heart, blood vessels, eyes, kidneys, and nerves. Stroke, one of such complications, is increasing every year. This study aims to investigate the prevalence of and risk factors for stroke among T2DM patients in Qatar. Methods: This was a secondary post hoc analysis of collected data from our previous study titled “Association of Vitamin D deficiency with dyslipidemia, glycemic control, and microalbuminuria in patients with T2DM in Qatar.” Results: The prevalence of stroke among our patients was 3.8%. A comparison between stroke and no-stroke groups showed a significant association between stroke and other diseases, namely, chronic kidney diseases (CKD) (p=0.007), coronary artery disease (CAD) (p=0.010), peripheral vascular disease (PVD) (p<0.001), retinopathy (p=0.044), prolonged duration of diabetes mellitus (DM) (p=0.041), glycated hemoglobin (HbA1c) (p=0.006), and a high serum creatinine level (p=0.003). In the multivariate analysis, we identified the following variables as independent risk factors for stroke in patients with T2DM: male gender, CKD, CAD, PVD, high HbA1c, a high creatinine level, and prolonged duration of DM. Conclusion: The prevalence of stroke among T2DM patients in Qatar was around 3.8%. The main risk factors were male gender, CKD, CAD, PVD, high HbA1c, prolonged duration of DM, and a high level of creatinine.

Karishma Karishma

The mechanistic insight of polyphenols in calcium oxalate urolithiasis mitigation

About 12% of the world's population is affected by different forms of urolithiasis, of which the recurrence rate in females is 47–60% and in males is 70–80%. Standard therapeutic agents (allopurinol, citrate, cystone and thiazide diuretics) prevent and treat urolithiasis. Still, these are not universally-effective due to common kidney stone relapse and other side effects. Surgical treatment causes long-term renal damage, hypertension and stone recurrence. Polyphenols, the plant-derived bioactive molecules, have showed protection against cancers, cardiovascular diseases, diabetes, osteoporosis and neurodegenerative diseases, among several other ailments. The role of these phytochemicals in urolithiasis management is emerging. Hence, the present review discusses peer-reviewed published literature to date on this aspect and highlights that polyphenols could effectively inhibit the formation of calcium oxalate urinary stones (most common renal stone), correlating with their antioxidant, anti-inflammatory, diuretic and angiotensin-converting enzyme (ACE) inhibition. Further, we have proposed the prospects and challenges in developing plant polyphenols into drugs against kidney stone prevention. This review might be a stepping stone for further investigation into the clinical implications of polyphenols in urolithiasis remediation.

Dr. Salman Ahmed Dr. salman ahmed

Kompetensi pedagogik guru dalam melaksanakan pembelajaran tematik di madrasah ibtidaiyah miftahul hidayah tegalsari banyuwangi

Kompetensi pedagogik merupakan kemampuan yang harus dimiliki guru dalam mengelola pembelajaran. Berkaitan dengan pengelolaan Pembelajaran Tematik fakta di sekolah menunjukkan banyak guru belum sepenuhnya mampu mengimplementasikan pembelajaran yang memiliki prinsip mengintegrasikan banyak materi. Untuk itu, penelitian ini bertujuan untuk mendeskripsikan kemampuan guru: 1) Memahami peserta didik dalam melaksanakan Pembelajaran Tematik di MI Miftahul Hidayah Tegalsari Tahun Pelajaran 2018/2019. 2) Merencanakan pembelajaran dalam melaksanakan Pembelajaran Tematik di MI Miftahul Hidayah Tegalsari Tahun Pelajaran 2018/2019. 3) Melaksanakan pembelajaran pada Pembelajaran Tematik di MI Miftahul Hidayah Tegalsari Tahun Pelajaran 2018/2019. 4) Mengevaluasi hasil belajar dalam melaksanakan Pembelajaran Tematik di MI Miftahul Hidayah Tegalsari Tahun Pelajaran 2018/2019. Hasil penelitian menunjukkan bahwa: 1) Kemampuan guru memahami peserta didik sudah sesuai indikator kompetensi pedagogik. 2) Kemampuan guru merencanakan pembelajaran sudah sesuai dengan indikator kompetensi pedagogik. 3) Kemampuan guru dalam melaksanakan pembelajaran ada satu indikator yang perlu diperbaiki. 4) Kemampuan dalam mengevaluasi hasil belajar sudah sesuai dengan indikator kompetensi pedagogik.

EDUCARE: Journal of Primary Education Educare: journal of primary education

The need to revive the legacy of education in libya

Libya is a country with a great scholastic minds and intellectuals. They have some older universities like Al-Fateh University, Tripoli, Al-Arab Medical University, Benghazi or Garyounis University and Libyan International Medical University (Private). Some of the courses conducted by these universities were recognized throughout the world. With civil unrest and the devastation created by the internal conflicts had dented the whole country affecting education to a great extent. Educational institutions are the pillars who build responsible citizens with social and economic commitment. The recent reporting of the decline in the standard of education in world rankings have affected many intellectual minds including faculty from different universities of Libya. The ranking is not a reflection of the standard and standing of many university members belonging to all the faculties including humanities, science and medicine. It will be wise to introspect and reflect the status of education and the role of University in the upliftment of the standard of education.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

Factors influencing social inclusion of women :a study on entrepreneurial support system in tripura

The research paper aims to find out the relevance of the existing support system for accelerating women entrepreneurship development and how these entrepreneurial support services of various Institutions expedite the process of social inclusion of women. The study has been conducted in the West Tripura District between January to August 2022. A total of 385 women entrepreneurs who were trained under government institutions were considered as the sample size. The primary data was collected directly from the field on basis of secondary information from Government Departments. The purposive sampling method has been deployed to identify the respondents for conducting the sample survey .

Md. Abdur Rahman Choudhury Md. abdur rahman choudhury

Mechanics insights of curcumin in myocardial ischemia: where are we standing?

Cardiovascular disorders are known as one of the leading health problems which are associated with mortality worldwide. Myocardial ischemia (MI) is the improper blood supply to the myocardium, which leads to severe complications to life-threatening problems like AMI, atherosclerosis, hypertension, cardiac hypertrophy, as well as diabetic-associated complications such as diabetic atherosclerosis/cardiomyopathy/hypertension. Despite several efforts, the current therapeutic platforms are unrelated to significant results. Hence, it seems that developing novel therapies is required. Increasing evidence indicates that curcumin (CRC) acts as a cardioprotective agent. Given that CRC and its analogues exert their cardioprotective effects via affecting various cardiovascular disease-related mechanisms (i.e., Inflammation and oxidative stress). Herein, we have highlighted the protective impacts of CRC against MI for the first time. This review might be a stepping stone for further investigation into the clinical implications of the CRC against MI. Furthermore, it highlights a legitimate concern for the scientific community, seeking novel techniques and characteristic dynamic biopharmaceuticals against myocardial ischemia.

Dr. Salman Ahmed Dr. salman ahmed

A study to determine impact of life style, body mass index and dietary habits on blood pressure among nursing students at selected nursing college , vijayapur

A study to evaluate the influence of body mass index, life styles and dietary habits on blood pressure among the nursing students at selected nursing college of Vijayapur. The objective of the study is to assess relationship of life style factors, body mass index and dietary habits with blood pressure. A sample of 500 nursing students was included in the study. The study result showed there is significant association between body mass index, life style dietary habits and blood pressure

Shwetha hitnal Shwetha hitnal

Modelling the impact of environmental responsibility on the development of enterprises

BACKGROUND AND OBJECTIVES: The requirements of stakeholders for the qualitative transformation of the approaches of industrial enterprises – environmental users to introduction of economic activities cause an increase in the role of environmental responsibility as their strategic priority for development. The purpose of the study is to improve the practical tools for calculating and developing strategies for the development of environmental responsibility of industrial enterprises. METHODS: In the study, tools for assessing the level of environmental initiative of an industrial enterprise as an integrated indicator of environmental initiative are suggested. It is expressed as the arithmetic mean of ten factors of environmentally proactive behavior of industrial enterprises. To achieve the objectives of the study, methods of criterion-qualitative assessment are suggested, such as expert assessment and survey. The assessment system includes ten factors rated on a 10-point scale and weighted by significance. The integrated indicator of the environmental initiative acquires values within, is a stimulant of environmental responsibility. FINDING: One justified a scientific and methodological approach to assessing the level of environmental responsibility or the industrial enterprise, including calculation of the corresponding taxonomic indicator with consideration of the quantitative factors of its environmental responsibility and the qualitative and quantitative factors of environmental initiative. This enables the possibility to assess the relevant state of environmental responsibility and determine the volumes for further correction of the ecological strategy for the development of the industrial enterprise. CONCLUSION: As a conclusion, practical recommendations are made for the implementation of organizational and economic support of environmental responsibility in the development strategy of an industrial enterprise taking into account the impact of its environmental initiative and environmental duty. The level of environmental responsibility of industrial enterprises taken into account when developing recommendations on adjustment of their environmental strategy of development is determined, which as a whole allowed to form organizational and economic support for environmental responsibility of the enterprises under study. Thus, an enterprise, which only ensures compliance with environmental emission standards (compensation strategy or sufficiency strategy) cannot be characterized by a high level of environmental responsibility. To ensure a high level of environmental responsibility, an industrial enterprise must rely on a proactive strategy or a strategy for sustainable use of nature.

Professor J. Nouri Professor j. nouri

Elevating standards: providing quality higher education in telangana

Telangana, a rapidly developing state in India, is committed to transforming its higher education landscape to meet the demands of the 21st century. This abstract outlines the key strategies and initiatives being implemented to elevate educational standards and ensure that students receive a world-class learning experience. This paper explores the efforts and strategies implemented to elevate the standards of higher education in Telangana, focusing on the challenges and opportunities encountered in delivering quality education. Over the past decade, Telangana has taken significant steps to enhance its higher education system by improving infrastructure, curriculum, teaching methodologies, and fostering collaborations with national and international institutions. The introduction of state-specific initiatives, such as the Telangana Academy for Skill and Knowledge (TASK), along with reforms in university governance, accreditation processes, and the promotion of research and innovation, has played a crucial role in improving educational outcomes. The paper also delves into the socio-economic impact of these improvements, particularly the increased employability of graduates, their contributions to the local economy, and the role of emerging institutions like Young India Skill University. By addressing both the successes and ongoing challenges, this study aims to provide insights into how quality higher education can be a catalyst for regional development and social mobility in Telangana.

Dr Gedam Kamalakar Dr gedam kamalakar

Environmental social and governance performance in banking sector: a bibliometric study

Financial sector needs special attention pertaining to incorporation of the ESG criteria. Economic and financial issues coupled with climate change would have negative impact on the stability of financial institutions. This research paper attempts to synthesize and summarise scholarly articles published in Scopus database on ESG domain with reference to banking sector using bibliometric analysis. The objective of this review paper is to understand from past literature the trajectory of studies in the domain of ESG. There is a substantial growth in frequency of publication in the year 2022 along with annual growth of around 30 percent during 2015-2023. Bibliometric with MS-Excel, R-Studio and VOS-viewer were used to identify and analyze research trends related to the number of studies, research fields, authors, nations, institutions, and keywords. The important keywords identified in the bibliometric analysis were sustainability, corporate social responsibility, sustainable finance, banks performance.

Dr. Mohammed Nizamuddin Dr. mohammed nizamuddin

La condition féminine et l’homosexualité dans une femme de trop d’issoufi dicko et ah ! nos maris, ces grands inconnus ! de dafiatou ba

La socialisation en Afrique de l’Ouest se fait par des canaux normatifs dont le mariage. Ce lien sacré, scellé par les Hommes et béni par Dieu, est une nécessité humaine et reste un goulot social pour plusieurs femmes. Sur cette entité géographique patriarcale, la condition féminine relève très souvent d’’un chemin de croix’ pour un épanouissement multiforme. Issoufi DICKO et Safiatou BA se saisissent de cette facette de la thématique du genre pour questionner les vies et les règles traditionnelles en contexte de modernité. Les deux jeunes écrivains maliens portent, entre condition féminine et inversion sexuelle, un regard sans complaisance sur leur société en profonde mutation. Trame nourricière de leurs ouvrages respectifs, ces thèmes leur permettent de mettre en scène des personnages hauts en couleur et en courage. Contrariées en partie par leurs quotidiens et la vie, le système patriarcal et l’embrigadement socioreligieux, leurs héroïnes s’indignent et se révoltent contre les sorts qui leur sont imposés. Défiant les règles de la vie en couple et celles socio-culturelles, elles s’érigent en rempart des dérives sociales perpétrées contre les femmes. Parallèlement à la condition féminine et les conflictualités de la vie en couple, le lesbianisme balbutiant au Mali est convoqué. Issoufi DICKO et Safiatou BA décrivent méticuleusement les arcanes de son enracinement progressif. Cette contribution aborde, avec la méthode qualitative, la condition féminine et l’homosexualité au Mali, entre fiction et réalité sociale. L’objectif de cette contribution est d’analyser la condition féminine et l’homosexualité à travers les deux romans.

Assanvo

Therapeutic potential of marine peptides in prostate cancer: mechanistic insights

Prostate cancer (PCa) is the leading cause of cancer death in men, and its treatment is commonly associated with severe adverse effects. So, new treatment modalities are needed. In this context, natural compounds have been widely explored for their anti-PCa properties. Aquatic organisms contain numerous potential medications. Anticancer peptides are less toxic to normal cells and provide a productive treatment approach via multiple mechanisms, including altered cell viability, apoptosis, cell migration/invasion, suppression of angiogenesis and microtubule balance disturbances. This review sheds light on marine peptides as efficacious and safe therapeutic agents for PCa.

Dr. Salman Ahmed Dr. salman ahmed

The impact of implementing a pharmacy triage system on the reduction of patients’ waiting time in the fourth floor outpatient pharmacy at hamad general hospital, qatar

Background and Objectives: The outpatient department (OPD) pharmacy is a section of the hospital pharmacy that helps patients obtain their prescribed medications. However, on-time delivery of medications and patients’ convenient access to the pharmacy are the hallmarks of a well-designed health-care system. Therefore, he aim of this study was to develop a pharmacy triage tool to improve patient flow and reduce waiting time in the fourth-floor pharmacy at Hamad General Hospital (HGH). Methods: This prospective and observational study was conducted on 14,740 patients who attended the OPD pharmacy (HGH, Qatar) between January 15, 2022 and March 15, 2022. This prospective and observational study consisted of three periods: A root cause analysis, a pre-intervention period of 1 month (January 15, 2021–February 14, 2021) and an intervention period of 1 month (15 February–15 March). We developed a pharmacy triage tool to improve patient flow and reduce waiting time by identifying patients who need their medications to be dispensed, as well as classifying patients to get the right patient to the right place and implementing a patient flow system to improve efficiency spends in pharmacy queues. Results: The results of this study showed that the use of the triage system in the pharmacy reduced the average waiting time of patients from 50 min to 15 min. The results were statistically significant at p<0.0001. Conclusion: We concluded that applying the pharmacy triage tool improved quality of services in health-care systems and decreased waiting time in the OPD pharmacy. The pharmacy triage tool is a new approach to enhancing the quality of healthcare and leads to an increase in the efficiency of OPD pharmacies.

Karishma Karishma

Prevalence of acute infectious hepatitis in eastern libyan pediatrics

Viral hepatitis is one of the main public health concerns around the world. Even though infection management techniques have been implemented over the last few decades, eradication or significant reduction has remained a mystery. The purpose of this study is to look into the prevalence of acute infectious hepatitis in the East of Libya and how the type of virus, age, gender, clinical manifestations, and outcome are related. This is a hospital-based retrospective study. The data on the frequency and distribution of viral hepatitis based on age, gender, seasonal, clinical, and ultrasound findings, and the outcomes during a period of two years from January 2020 to December 2021 were collected and analyzed. Of the 0.39% (72 cases) of total hospital admissions (18340) under the age of 15 years old for acute infectious hepatitis patients, the most common age group was 5-12 years (79.6%). Winter accounted for 41.6% of all the cases. Females made up 65.3% of the cases. Jaundice was the most prevalent presentation (87.5%). Hepatomegaly was seen in 83.3% of the patients. Most of the cases have mild hyperbilirubinemia (5-9 mg/dL, 75.0%). Approximately 1/5th of the patients' serum glutamic-oxaloacetic transaminase (SGPT), and nearly 1/3rd of the patients' SGPT levels were in the range of 1000-2000. One patient's hepatitis C was positive, one patient's hepatitis B was positive, and 97.2% were positive for hepatitis A. 88.8% of the individuals recovered without complications, whereas 11.1% showed symptoms of hepatic failure but recovered. The present study indicates that acute hepatitis A is more prevalent, especially in the winter. Those who are females and 5-12 years of age were more affected by acute viral hepatitis in Libya.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

First report of post-vomiting subcutaneous peri-lacrimal drainage system emphysema

Subcutaneous emphysema is defined as a trapped air in tissues under the skin. This entity most often occurs in the chest wall and neck but can infrequently happen in other parts of the body like the orbital area [1]. The main mechanism of subcutaneous emphysema is the traumatic damage of the anatomical air-filled cavities or canals. Most of the rare, reported cases of orbital and periorbital emphysema were described in adults as complications of several types of traumas, including direct trauma, recent or previous surgery [2,3], barotrauma secondary to non-invasive ventilation, such as continuous positive airway pressure therapy [4], and even post forceful noseblowing [5]. In this report, we described the first reported case of post-vomiting subcutaneous emphysema surrounding the medial canthus of the right eye in a 10-year-old boy.

Karishma Karishma

Training &development initiative for entrepreneurship promotion by tgb -resti : an analysis from state level bankers committee database

Rural Self Employment Training Institutes (RSETIs) functions as a structural framework for skill development & entrepreneurship development training laid down by Ministry of Rural Development, Government of India in the year 2009. The concept of RSETI is bagged from the RUDSETIs (Rural Development & Self Employment Training Institutes), the brain child of Dr. D. Veerendra Heggade. RSETIs have 65 approved courses as per National Skill Qualification Framework (NSQF) under which they offer different types of Entrepreneurship Development Programme (EDP). All the programmes are short term residential training with 2 (two) years hand holding support. State Level Bankers Committee data revealed that through the RSETI training, huge number of unemployed youths started their own enterprise with or without bank finance and also getting the scopes of Self-employment. This particular study took a humble effort to publicize the role of TGB-RSETI in Tripura in respect to unemployment reduction through entrepreneurship development. The entire study is based on secondary data (2009-10 to 2022-23) retrieved from SBLC, Tripura website data.

Md. Abdur Rahman Choudhury Md. abdur rahman choudhury

Prevalence of tuberculosis in shabwah governorate, yemen: a cross-sectional study

Background: There is a lack of data on current tuberculosis (TB) burden in Shabwah Governorates in Yemen. This study aimed to investigate the prevalence, epidemiology, and outcomes of TB disease in Shabwah Governorate, Yemen. Materials and Methods: This cross-sectional study was conducted at the National TB Program (NTP) Center in Ataq City, Shabwah Governorate, Yemen. The study involved TB patients of different ages who were notified at the center between January 1, 2021, and December 31, 2021. Results: We involved a total of 123 new active TB cases, including 86 (69.9%) with pulmonary TB (PTB) and 37 (30.1%) with extrapulmonary TB (EPTB). The total prevalence of TB disease during the year 2021 was 14.5 new TB cases per 100,000 population, while the median age of the study population was 34 years. The majority of the cases (23.6%) belonged to age group 15–24 years. There was a slightly higher preponderance of males 54.5% (n=67). EPTB was detected in 37 (30.1%) patients with lymph node TB being the most common manifestation [17 (46.0%)]. All patients received four-drug anti-TB therapies for 6–12 months. Most patients 111 (90.3%) were cured, and 2 (1.6%) patients died during the course of the disease, while 10 (8.1%) patients were lost during follow-up. Conclusion: The prevalence of TB in Shabwah Governorate was 14.5/100,000 population. Male patients and younger age groups were more affected, while the lymph nodes were the main extrapulmonary sites involved and the cure rate was 90.2%. The results of the study indicate the need to revise the notification form for active TB cases and to expand NTP activities to focus on targeted screening for active TB cases in high-risk groups to close the gap in unidentified TB cases.

Karishma Karishma

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