The current study was designed to explore the anti-inflammatory effects of the crude hexane and ethanol extracts of the leaves and male flowers of Luffa cylindrica (L.) Roem., (sponge gourds) to validate its folk use. These extracts produced significant anti-inflammatory effects (p.o.) at doses of 500, 750 and 1000 mg/kg b.w. in carrageenin-induced paw oedema in rats compared to those obtained with indomethacin. The results of the present study provide evidence for the anti-inflammatory properties of the leaves and male flowers of Luffa cylindrica, which have potential therapeutic applications for inflammatory diseases.
In the last decade, we have observed the usage of artificial intelligence algorithms and machine learning models in industry, education, healthcare, entertainment, and several other areas. In this paper, we focus on using machine learning algorithms in the loan approval process of financial institutions. First, we briefly review some prior research papers that dealt with loan approval predictions using machine learning models. Next, we analyze the loan approval prediction dataset we downloaded from Kaggle, which was used in this paper to compare several machine learning classification models. During this analysis, we observed that credit scores and loan terms are the attributes that probably most affect the result. Next, we divided the dataset into a training set (80%) and a test set (20%). We trained 27 various machine learning models in MATLAB. Three models were optimized with Bayesian optimization to find the best hyperparameters with minimum error. We used 5-fold cross-validation for the validations to prevent overfitting during the training. In the following step, we used the test set on trained models to measure the models' accuracy on unseen data. The result showed that the best accuracy both on validation and test data, more than 98%, was reached with neural networks and ensemble classification models.
Over the years, pharmacy has developed from a simple floor stock system to a complex unit dose, I.V. additive, and clinical pharmacy program. This development would have never been possible without the support of the nursing, medical, and administrative staff. The support of obtained slowly by developing services that increase the pharmacist's credibility as a team member concerned with the pediatric and neonate patients. These services include a unit dose program, I.V. additive program, drug information services, and pharmacy medication program. One area in which pharmacist does not obtain a background from generalized training is the area of pediatric dosing. Pediatric pharmacists must learn in clinical practice the proper dosing of the pediatric patient and neonate patient. The dose must be checked periodically. In the premature or newborn infant, the pharmacist must consider the immature renal and hepatic function so that he/she does not overdose initially and then underdose as the infant grows and matures. Neonates are a special group of children, they are less than 30 days, and within this group preterm babies (that means less than 37 weeks). Determining the correct dose for drugs used to treat neonates is a critically vital factor. Prematurity affects kidney and liver function and the proper adjustment of drug doses is crucial [1]. The absence of drug level necessitates the adjustment of drug doses and the presence of qualified oriented dependable pharmacists. Drug doses are not numbers, or decimals used within the therapeutic range. Neonatal Intensive Care Unit (NICU) needs a system for the calculation and preparation of drugs [2].
Mediterranean journal of pharmacy and pharmaceutical sciences
Conservation of Biodiversity is an activity must carry out by all individuals in the world to share the benefits derived from biodiversity. It is a critical task to conduct the biodiversity census and conservation (Biodiversity C & C or Biodiversity C2). Throughout the world several Governament and Non-Governamental organizations work together as a unit to maintain our biodiversity in safe mode. India is a mega diverse country with rich biodiversity. The development of modern science and technologies have increased the value of biodiversity and associated traditional knowledge. To save valuable biodiversity and traditional knowledge of our country, National biodiversity board and State biodiversity board constantly involved in this approach and biodiversity law's support to conserve the living diversity.
The valuable effects of regular exercise for promotion of health and therapy of diseases were obviously evaluated. The notion that exercise can be considered as a medication has been hypothesized. The growing problems of obesity and non-communicable diseases have placed a great burden on public health experts to promote physical literacy and physical activity among the modern day population. Physical literacy and physical activity have become the cornerstones of women’s health. Women have certain special needs that includes reproductive health. Increased physical activity and maintaining normal body image and body weight will help a woman attain physical, mental and spiritual development. With the growing number of women with obesity and the implication of obesity as one of the main risk factors for non-communicable diseases like diabetes, hypertension, stroke and osteoarthritis, a knowledge and awareness about physical activity is essential. Thus, physical activity is a fundamental aspect of the improvement of motor skills and work performance, allowing a better healthy lifestyle. Physical exercise is effective to be measured as a drug, however, more care should be considered to the dosing and individual variations between genders.
Mediterranean journal of pharmacy and pharmaceutical sciences
To test and popularize the Krishi Vigyan Kendra, Barmer-II, Gudamalami, Rajasthan recommended Enhance the Productivity of Ridge gourd (Luffa acutangula L.) Cultivation in Net Trellis System in Barmer District of Rajasthan, On Farm Trials (OFT’s) were conducted during the kharif season of 2019 and 2020 in farmers participatory mode at three locations in Barmer District of Rajasthan. The experiment consisted of two treatments viz., recommended practice (Net trellis system) and farmers practice (Furrow). Net trellis system had significant increase number of picking (13), fruit length (43.33 cm) and fruit weight (210 g) as compared to farmer’s practice (07, 22.67 cm and 101.5 g) during both the year as well as pooled data. The two year average fruit yields of net trellis system have shown doubled production over farmers practice method. Net trellis system was recorded increase yield for 73.57% (138.06 t/ha) as compared to farmers practice (79.54 t/ha) during both the year as well as pooled data. Similarly, the net returns and B:C ratio also revealed that maximum under net trellis system during both the year as well as pooled data Rs 232790 per hectare and 3.36:1 as compared to farmers practice Rs 89913.5 per hectare and 2.30:1. Net trellis system had significant reduce the damage of pest and soil borne diseases and improve the quality of fruits
Network on a chip is a concept in which a single silicon chip is used to implement the com-munication features of large-scale to very large-scale integration systems. For high-end System on Chip de-signs, Network on Chip is considered the best integrated solution. NoC has several advantages over dedicat-ed wiring and buses i.e. increased bandwidth, low latency, less power consumption and scalability. Reduc-tion in the latency (end-to-end latency and network latency), loss probability, energy consumption and re-sponse time are the basic parameters which are considered by the researchers for the optimization of the networks-on-chip topologies. In this paper we review the most popular technologies and also some recent topologies for interconnection networks. We study their performance and summarize their strengths & weakness.
The very first recruitment for a public relations practitioner in Malaysia was encountered in 1948 and was advertised by the federal government of the British Colony in Malaya. This paper examines the subsequent advertisements after Malaya sought independence from the British colonial government. A total of eleven recruitment advertisements were found before the formation of Malaysia on the 16th September 1963. This paper outlines the advertisers, the titles of positions, as well as their qualifications and duties. The results show that the job requirement mainly came from the federal and local governments. Generally, the duties were related to information services and some specific responsibilities.
Penelitian ini bertujuan untuk melihat seberapa besar dampak kualitas produk, persepsi konsumen dan brand image terhadap keputusan pembelian produk endorsement pada masyarakat di Medan dengan menggunakan word of mouth sebagai variabel moderasi. Sampel penelitian ini adalah sebesar 100 orang responden dengan teknik analisis data menggunakan analisis jalur (path analysis). Hasil dari penelitian ini menunjukkan kualitas produk, persepsi konsumen dan brand image berpengaruh terhadap keputusan pembelian produk endorsement pada masyarakat di Medan. Lebih lanjut, word of mouth tidak memoderasi kualitas produk terhadap keputusan pembelian dan juga tidak memoderasi persepsi konsumen terhadap keputusan pembelian namun word of mouth memoderasi brand image terhadap keputusan pembelian produk endorsement bagi masyarakat di Medan.
Introduction: Apophyseal avulsion fractures of the pelvis predominantly occur in adolescent athletes due to skeletal immaturity. The anterior inferior iliac spine (AIIS) is a rare but characteristic site of injury. Case Presentation: We report the case of a 15-year-old male football player who sustained a traumatic avulsion of the right AIIS. The diagnosis was confirmed radiologically, and the patient was managed conservatively. Results: The clinical course was favorable, with a return to sports at three months. Conclusion: Early diagnosis and conservative management typically allow full recovery in most cases.
This study was conducted to proposea hierarchical temporal memory (HTM) approach for fault detection in the Onitsha-Alaoji transmission line in Nigeria. Using a mixed research method, the study employed the Hawkins HTM model with two objectives and their corresponding research questions. The study gathered primary and secondary data to detect and evaluate faults in the Onitsha-Alaoji transmission line in Nigeria using HTM and compares its efficacy to current fault detection methods. With the use of simulation and descriptive methods of data analysis, results showed that partial discharge (PD) is the fault type that is being detected and it is commonly found as a fault leading to transmission line errors. More so, fault detection simulations were conducted at 40 km using typical power spectral density analysis. The first fundamental shifted from about 10 kHz to roughly 13 kHz during a fault. The HTM model outperformed sequence learning methods, resulting in a 90% mean test classification accuracy (CA) over extreme learning machine(ELM) and online sequential learning–extreme learning machine (OS-ELM), with OS-ELM performing poorly.The study concluded and recommended that the proposed HTM model be used to identify various PD fault types that plague the Onitsha-Alaoji transmission line in Nigeria. With the increased efficacy and reliability of the proposed model compared to existing methods, it is recommended for future implementation in this transmission line and potentially other fault-prone power transmission lines in Nigeria.
Although, antibiotics play a fundamental role in control of infectious diseases still the injudicious prescription of antibacterial agents and antibiotic resistance are a global problem. This study aims to assess prescribing pattern of antibiotics and to provide a baseline data about behaviors of physicians prescribing antibiotics during pediatric consultations. In this study, a total of 316 pediatric patients of both genders were receiving different antimicrobial therapy were evaluated during 2021 in pediatric health care services in Bayda, Libya. Data revealed that the average of drugs prescribed was 4.10 per patient while the average of antimicrobials was 2.30 per prescription. Most of the antibiotics were prescribed for the respiratory tract infections (34.0%) and followed by the urinary tract infections (29.0%). Cephalosporins and penicillins were the most common antibiotics prescribed in this study. In conclusion, these findings show the presence of polypharmacy and inappropriate prescribing pattern. To improve and minimize the unnecessary prescribing of antimicrobial agents, a continuous training program for physicians, as well as engaged pharmacists in health care services are needed.
Mediterranean journal of pharmacy and pharmaceutical sciences
BACKGROUND AND OBJECTIVES: Fixed-bed column has been considered an industrially feasible technique for phosphate removal from water. Besides the adsorption capacity, the effectiveness of an adsorbent is also determined by its reusability efficiency. In this study, phosphate removal by a synthesized amorphous zirconium (hydr)oxide/MgFe layered double hydroxides composite in a fixed-bed column system was examined. METHODS: The effects of flow rate, bed height, phosphate concentration, solution pH, and adsorbent particle size on the phosphate adsorption ability were examined through a series of continuous adsorption experiments. The appropriate breakthrough curve models, phosphate adsorption from real anaerobic sludge and synthetic seawater, column regeneration and reusability, and adsorption mechanism were also investigated for practical application feasibility. FINDINGS: The results showed that the increased bed height and phosphate concentration, and reduced flow rate, pH, and adsorbent particle size were found to increase the column adsorption capacity. The optimum adsorption capacity of 25.15 mg-P/g was obtained at pH 4. The coexistence of seawater ions had a positive effect on the phosphate adsorption capacity of the composite. Nearly complete phosphate desorption, with a desorption efficiency of 91.7%, could be effectively achieved by 0.1 N NaOH for an hour. Moreover, the initial adsorption capacity was maintained at approximately 83% even after eight adsorption-desorption cycles, indicating that the composite is economically feasible. The high phosphate adsorption capacity of the composite involves three main adsorption mechanisms, which are electrostatic attraction, inner-sphere complexation, and anion exchange, where the amorphous zirconium hydr(oxide) on the surface of the layered double hydroxides likely increased the number of active binding sites and surface area for adsorption. CONCLUSION: The amorphous zirconium (hydr)oxide/MgFe layered double hydroxides composite, with its high adsorption capacity and superior reusability, has the potential to be utilized as an adsorbent for phosphorus removal in practical wastewater treatment. This study provides insights into the design of amorphous zirconium (hydr)oxide/MgFe layered double hydroxides composite for phosphorus removal and recovery in a practical system.
The present study focused on analysing the impact of ‘Make in India’ campaign on FDI inflows in country. The research period is divided in two parts one is pre ‘MII’ & another is post ‘MII’ period. The analysis of ‘Make in India’ campaign is done to identify the scope of the campaign & methodology of working of various allied departments monitoring campaign. The present research work also attempted to take overview of various policy reforms initiated by Government of India to promote the FDI as well domestic investment in 25 sectors shortlisted under MII. The FDI inflows statistics reveals that, the post MII period is showing the highest growth in FDI equity inflows as compare to same period i.e. 2009- 2014. The MII initiative is one of the reason for the jump in FDI inflows. The overview of policy reforms shows that GOI through DIPP attempted to open almost all sectors for 100% FDI through automatic route. Government has provided multiple incentives for Foreign Investors to establish their manufacturing facilities in country but very negligible response has been seen in the nature of FDI equity inflows in the same period. Further results of study reveals that multiple ‘MOU’s have been signed by States & Central Governments, but they yet not converted in actual investments. The major reasons behind the same is lack of SWOT analysis through Governments before inviting the foreign investors. As well lack of basic infrastructure, land, lack of skilled manpower, cheap & un interrupted power supply to MIDC’s & SEZ’s is yet not successfully provided, lower rankings in Ease Of Doing Business (EODB), Global Manufacturing Competitiveness Index (GMCI) is also cause of concern & tumbling block in the success of MII mission..
This study investigated workforce diversity and secondary school administration in Rivers state. The design for the study was the descriptive survey. Two research questions and two hypotheses were raised to guide the study. Mean and standard deviation statistics were used to answer the research questions while the hypotheses were tested at 0.05 level of significance using z-test statistics. A sample size of 667 respondents, representing 90% of the entire population of 741 principals and vice principals from all the 247 pubic senior secondary schools in Rivers state was drawn using the stratified random sampling technique. A researcher-designed instrument titled Workforce Diversity Management Questionnaire (WOFDIMQ) was used for data collection. The instrument was validated by experts in the area of measurement and evaluation at the University of Port Harcourt. The reliability index determined for the instrument using Cronbach Alpha was 0.82. The findings of the study revealed that secondary school administrators do have some administrative strategies put in place for the management of the diversities among teachers. It was therefore recommended among others, that the government should make some specific provisions that will guide school administrators in the management of diversities among teachers. Also, school administrators should develop operational plans and strategies that are based on their specific peculiarities that will help maximize the advantages of diversities among teachers, while at the same time, minimize the inherent disadvantages.
Background and Objectives: The complications of type 2 diabetes mellitus (T2DM) can occur in some organs, such as the heart, blood vessels, eyes, kidneys, and nerves. Stroke, one of such complications, is increasing every year. This study aims to investigate the prevalence of and risk factors for stroke among T2DM patients in Qatar. Methods: This was a secondary post hoc analysis of collected data from our previous study titled “Association of Vitamin D deficiency with dyslipidemia, glycemic control, and microalbuminuria in patients with T2DM in Qatar.” Results: The prevalence of stroke among our patients was 3.8%. A comparison between stroke and no-stroke groups showed a significant association between stroke and other diseases, namely, chronic kidney diseases (CKD) (p=0.007), coronary artery disease (CAD) (p=0.010), peripheral vascular disease (PVD) (p<0.001), retinopathy (p=0.044), prolonged duration of diabetes mellitus (DM) (p=0.041), glycated hemoglobin (HbA1c) (p=0.006), and a high serum creatinine level (p=0.003). In the multivariate analysis, we identified the following variables as independent risk factors for stroke in patients with T2DM: male gender, CKD, CAD, PVD, high HbA1c, a high creatinine level, and prolonged duration of DM. Conclusion: The prevalence of stroke among T2DM patients in Qatar was around 3.8%. The main risk factors were male gender, CKD, CAD, PVD, high HbA1c, prolonged duration of DM, and a high level of creatinine.
Background: This study was conducted to determine the level of the public knowledge, attitudes and practices related to common eye diseases in the southern Indian population. Methods: A cross sectional population-based survey used a semi structured questionnaire on awareness, knowledge, attitude and practices related to eye diseases. Stratified multistage cluster random sampling method was used with a sample size of 867 adults >16 years based on, estimated awareness of cataract 70%, assuming an expected rate of 85%, design effect of 1.5, margin of error 4% with 95% confidence interval with 25% from urban areas and 75% from rural areas. A pilot study was conducted to validate the questions used in the main study. SPSS (version 19) used for analysis. Results: A total of 782/867 (90.1%) subjects participated in the survey, with females 47.4%. Awareness of major eye diseases for cataract 81.5%, glaucoma 47.8%, refractive error 74.3%, squint 89.0%, diabetic retinopathy 65.0% and age-related macular degeneration 36.7% respectively. 41.8% subjects reported wearing glasses either for distance, near or for both. Of the 777 subjects only 294 people underwent an eye examination by an ophthalmologist in the last two years (37.8%). 57.5% subjects had knowledge of the nearest eye care facility within five kilometers of their residence. Electronic media were the major source of information on eye health. Conclusions: Though the awareness levels of common eye diseases were quite high, the knowledge of cataract (10.4%) was poor. There is a need to increase the level of awareness for eye diseases like glaucoma and age-related macular degeneration.
OpenCitations is an infrastructure organization for open scholarship dedicated to the publication of open citation data as Linked Open Data using Semantic Web technologies, thereby providing a disruptive alternative to traditional proprietary citation indexes. Open citation data are valuable for bibliometric analysis, increasing the reproducibility of large-scale analyses by enabling publication of the source data. Following brief introductions to the development and benefits of open scholarship and to Semantic Web technologies, this paper describes OpenCitations and its data sets, tools, services, and activities. These include the OpenCitations Data Model; the SPAR (Semantic Publishing and Referencing) Ontologies; OpenCitations’ open software of generic applicability for searching, browsing, and providing REST APIs over resource description framework (RDF) triplestores; Open Citation Identifiers (OCIs) and the OpenCitations OCI Resolution Service; the OpenCitations Corpus (OCC), a database of open downloadable bibliographic and citation data made available in RDF under a Creative Commons public domain dedication; and the OpenCitations Indexes of open citation data, of which the first and largest is COCI, the OpenCitations Index of Crossref Open DOI-to-DOI Citations, which currently contains over 624 million bibliographic citations and is receiving considerable usage by the scholarly community.
formulation and evaluation of herbal face pace pack
Postpartum depression is a major maternal health problem after childbirth. It can start at any time within the first year after delivery and continue for several years. It is characterized by an inability to experience pleasure, anxiety symptoms, panic attacks, spontaneous crying and depressed mood. Some women with postpartum depression even have thoughts of harming their child and self-harm. The aim of this study is to find out the status of postpartum depression and the associated factors among postnatal mothers at first-, fourth- and sixth-month. This study is a prospective descriptive study, carried out in three major health facilities in Misurata. This study consists of three-part questionnaire. Part 1 covers demographic characteristics of the participants, while part 2 explores the associated risk factors according to the variables used. Part 3 constitutes for the psychological evaluation of the participants. Hundred mothers (age are between 15 and 43 years) were enrolled in this study. The findings revealed that prevalence of depression is 60% and 22% are suffering from borderline depression. Development of depression was strongly correlated with the sleeping disturbances, state of the neonate after birth, excess consumption of stimulants, less weight acceptance by mothers during pregnancy and infant illness. There was a weak relation between depression and delivery state, maternal admission to hospital during current pregnancy, and infant gender dissatisfaction. No correlation was found with development of depression regarding miscarriage, maternal medical problems after delivery, previous child sex, maternal age, education, parity or neonate weight. Thus, this study shows that a chance of having miscarriage and unhealthy neonate increases with advanced maternal age. It also shows that caesarean section is associated with bad neonatal outcomes, more weight gain and having gestational diabetes or preeclampsia during pregnancy. Maternal sleeping problems are more pronounced in the first month, attributing for the baby care, compared with fourth and sixth months. The study indicates that depression is a common state of psychiatric disorders among Libyan women and should have an appropriate attention by physicians and gynecologists.
Mediterranean journal of pharmacy and pharmaceutical sciences