Metronidazole-induced neurotoxicity: is iron a contributing factor?

Metronidazole-induced neurotoxicity is a rising challenge in managing susceptible infections. The mechanisms involved in metronidazole-induced neurotoxicity are not fully unraveled. This study aimed to explore the effect of metronidazole on iron homeostasis in SH-SY5Y neuroblastoma cells. Confluent SH-SY5Y neuroblastoma cells were treated with different concentrations of 1.0, 10, 25, 50, 100, and 250 µM of metronidazole only or in combination with 20 µM iron. DMSO or culture media was used as control. Viability and ferritin assays were conducted on the treated cells. The treatments were for 24 hours, 48 hours, and 72 hours, respectively. In the viability assay, doses of metronidazole reduced the viability of SH-SY5Y neuroblastoma cells in a time and concentration-dependent manner. After 24-hour treatment, 250 µM metronidazole significantly reduced cell viability while 50 µM, 100 µM and 250 µM metronidazole reduced considerably viability only after 48-hour and 72-hour compared with control. Different doses of metronidazole 50 µM, 100 µM, and 250 µM in 20 µM iron reduced viability in a time-dependent manner in all the test periods. Metronidazole also induced a time- and concentration-dependent increase (p<0.05) in cellular iron uptake in the 48-hour and 72-hour treated cells in concentrations above 25 µM metronidazole. It is concluded that metronidazole induces a time and concentration-dependent iron overload and consequent cell death in SH-SY5Y neuroblastoma cells and this may contribute to the mechanism of metronidazole-induced neurotoxicity.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

Competencies and professional development needs of kindergarten teachers

The study identified the level of competencies and the extent of professional development needs of kindergarten teachers in the Sultan Kudarat Division, during the school year 2019 - 2020. The study employed a descriptive method. The study involved 54 kindergarten teachers in the division in accomplishing the 12-item self-assessment instrument. Data were analyzed using descriptive statistics. The results revealed that kindergarten teachers have a high level of competencies in content knowledge and pedagogy, learning environment and diversity of learners, curriculum and planning, and assessment and reporting. These indicate that they possess almost all of the competencies of efficient teachers. Results further revealed a very high extent of professional needs in content knowledge and pedagogy and the learning environment and diversity of learners, while they had a high extent of professional needs in the remaining domains. Since they reported very high priorities in content knowledge and pedagogy and the learning environment and diversity of learners, these areas would be the main considerations in the crafting of a professional development plan.

Manuel Caingcoy Manuel caingcoy

Approaching the slums in pune, india, empowering and uplifting the community with education and health reforms

With the expansion of human societies, extending up to almost every corner of the earth, transforming it to be as per their condition, humankind has proved their extraordinary dominance on the earth. The dominating attitude of humans has not resulted pleasantly every time. Poverty is one such curse that has shamed the progressing world community. Christianity has dedicated a large portion of its ministerial approach towards the underprivileged. This paper presents a missiological approach to uplift the slum dwellers in the city of Pune with education and health reforms. A similar project was experimented in 2014 among homeless people. The project did well and the results were significantly progressive and potential. It is assumed that this paper will bring an insightful approach that benefits the slums in Pune and enhance the “serving the humanity” aspect of the Christian mission.

Santosh kumar Santosh kumar

A comprehensive review for security analysis of iot platforms

Due to the rapid growth in the field of science and technology, IoT (Internet of Things) has become emerging technique for connecting heterogeneous technologies related to our daily needs that can affect our lives tremendously. It allows the devices to be connected to each other and controlled or monitored through handheld devices. The IoT network is a heterogeneous network that links several small hardware restriction devices, and where conventional security architectures and techniques cannot be used. So, providing protection to the IoT network involves a diverse range of specialized techniques and architectures. This paper focuses on the requirements of defense, current state of the art and future directions in the field of IoT.

Dr. Chandrashekhar Uppin Dr. chandrashekhar uppin

Effects of hypersaline conditions on the growth and survival of larval red drum-(sciaenops ocellatus)

Texas bays and estuaries experience salinity fluctuations (e.g., droughts, reduced freshwater inflows and hurricanes) caused by natural weather and climate change. This could have impacts on red drum Sciaenops ocellatus (Linnaeus) early life stages beacause red drum spend their early life stage at the shallow bays and estuarine waters of Texas Bay. The purpose of the present study is to evaluate the impact of high salinity concentrations on the survival, growth and development of red drum eggs and larvae. Red drum brood stocks were collected from wild stocks throughout the lower Texas coast and were held in hatchery tanks (13,250 L) until spawning. The water quality conditions were maintained at a salinity of 38ppt and seawater temperature of 25°C. The red drum eggs were hatched at a wide range of salinity treatments (28-48ppt). Egg hatch-out rates and larvae growth were reduced at the lowest (28ppt) and highest (48ppt) salinity treatments. Hypersalinity (≥ 40ppt) and a temperature of 25ºC affected the hatching success of red drum eggs. The percentage of egg hatching success and length of larvae were reduced in both lower (28ppt) and/or hypersalinity (48ppt). This study shows that red drum eggs can hatch within a wide range of salinities with best hatch-out and growth rates occurring between 33 – 43ppt. It also suggests that climate change that produces global warming can keep the increasing environmental salinity of the Texas bay which might have an impact on the development of the early stages of the red drum in their natural environment.

Irma Kesaulya Irma kesaulya

Application of artificial neural networks in predicting sub-base cbr values

Establishing a realistic working profile of soil properties has been, and is still, one of the most challenging problems facing Geo-technical engineers, especially for CBR results. In the present study a neural-network approach is used to tackle this problem. Source data of a series of California Bearing Ratio Tests (CBR) performed at the Laboratory and Geo-technical Experimental Site. This will be useful for training and testing an artificial neural network. The developed neural network will be showing the prediction of CBR values of the site studied. Data are then generated for constructing the profiles of the CBR values using the trained neural network. This study might be useful for the future as this process will reduce the work on procedure and graphical calculations.

Mayura

Influence of demographic and socio-economic factors on locus of control on residents of select suburbs in mumbai city

The orientation he/she chooses has a bearing on his/her long-term success. This orientation is known as your "locus of control." Its study dates back to the 1960s, with Julian Rotter's investigation into how people's behaviours and attitudes affected the outcomes of their lives. Locus of control has been defined as the degree to which an individual perceives having control over the environment (Rotter, 1966). According to Rotter (1975), there are two types of control, internal and external, which anchor a continuum that approximates a normal distribution. People are said to have an internal locus of control when they believe reinforcements are contingent upon their own behaviour or stable personal characteristics. External locus of control results when people believe that reinforcements are due to luck, fate, or powerful others outside of their control. Current study focuses on investigating the influence of demographic variables (age, gender, education level), marital status and socio economic status (occupation, income) on the level of internal/ external locus of control with the help of data collected from residents (aged between 20 and 50) of a select suburbs in Mumbai city. On analysing the data so collected, it is found that age has a major influence on an individual’s level of internal locus of control.

Nandini Nandini

Ecological niche modeling to assessment of potential distribution of neodiprion abietis (harris, 1841) (insecta, hymenoptera, diprionidae) in eurasia

In the article first assesses the potential distribution in Eurasia of Neodiprion abietis (Harris, 1841) first time assessed. The species id a widely distributed in North America fir and spruce defoliator, intercepted in 2016 in the Netherlands. Analysis of the literature data on the known distribution and host plants of the species is given. Insufficient data for ecological modeling is shown, which causes a high degree of uncertainty in assessment of potential range. The results of modeling the potential range of the species using several algorithms are presented. The reliability of the obtained models and the importance of bio-climatic environmental variables for species distribution are assessed.

Svedbergopen

Virtual reality based therapy and parkinson's disease

Parkinson’s disease (PD) is one of the most common neurodegenerative disorders worldwide. It is mainly associated with a loss of dopaminergic neurons in the substantia nigra pars compacta

Nagarjuna narayanasetti

In-vitro evaluation of chromium tolerant plant growth promoting bacteria from tannery sludge sample, dindugal, tamil nadu, india

Industrial waste is one of the most essential sources of contamination in the environment. Chromium (Cr) is a toxic heavy metal, a major contaminant in tannery wastes and its accumulation in soil and water is a major environmental concern today. In the present study, an attempt was made and investigated the status of different beneficial microbes particularly plant growth promoting rhizobacteria (PGPR) from tannery sludge samples collected from tannery effluent treatment plant at Dindugal, Tamil Nadu, India. Experiments were conducted and evaluated their chromium heavy metal tolerance abilities and plant growth promoting activities under in-vitro. Based on molecular analysis, the PGPRs were identified as Achromobacter xylosoxidans (LK391696), Azotobacter vinelandii (LK391702) and. The production of IAA was found to be high by Achromobacter xylosoxidans (46μg/ml) followed by Azospirillum lipoferum (30μg/ml). Phosphate solublization activity was also found to be positive in all these PGPR isolates. Significance of these results revealed that there is a possibility of using these potential PGPRs for bioremediation of chromium contaminated sites and also as good plant growth promoter.

Dr. SARANYA DEVI K Dr. saranya devi k

Assessing nutritional needs of oncology patients undergoing chemotherapy at bhagwan mahaveer cancer hospital & research centre, jaipur: development of an educational booklet

Background: Cancer is the word used for a tumor that spreads & destroys the host and is one of the leading causes of morbidity and mortality in developed and developing countries. Good nutrition is important for good health. Methods: Non-experimental descriptive research design was adopted for a study to assess knowledge on meeting nutritional needs among 100 oncology patients receiving chemotherapy at Bhagwan Mahaveer Cancer Hospital & Research Centre, Jaipur. Sample selection using a non-probability convenient sampling technique. Data were collected through a self-developed structured knowledge questionnaire. Results: Our results revealed that the majority of cancer patients, 43%, were in the age group of 31-40 years, 39% had no formal education, 32% had secondary education, and 17% had primary education. 76% were males, 24% were female, and 87% of participants did not have a family history of cancer. 55.23% of patients reported that nurses did counselling. The majority (67%) of respondents reported that they had previous information on meeting nutritional needs through diet counselling, and 33% reported they didn’t have any information about meeting nutritional needs. Most (45%) of cancer patients had poor knowledge, 26% had average knowledge, and 29% had good knowledge scoring. Conclusion:Conclusion:Conclusion:Conclusion:Conclusion:Conclusion:Conclusion:Conclusion:Conclusion:Conclusion:Conclusion: We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge We concluded that results show most (45%) of oncology patients receiving chemotherapy had poor knowledge meeting nutritionmeeting nutrition meeting nutrition meeting nutrition meeting nutritionmeeting nutrition meeting nutrition meeting nutritionmeeting nutritionmeeting nutritionmeeting nutritionmeeting nutritional needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. 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However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that al needs during chemotherapy. However, the researcher developed an information booklet, and he hopes that the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy the booklet will surely enhance oncology patient’s knowledge of meeting nutritional needs during chemotherapy .

Dr K C Yadav Dr k c yadav

A case study on csr initiatives with special reference to hindustan unilever ltd

Corporate Social Responsibility (CSR) is a concept with many definitions and practices. The way it is understood and implemented differs greatly for each company and country. Moreover, CSR is a very broad concept that addresses many and various topics such as human rights, corporate governance, health and safety, environmental effects, working conditions and contribution to economic development. Whatever the definition is, the purpose of CSR is to drive change towards sustainability. Corporate social responsibility (CSR) is now seen as an integral part of corporate strategy. The main purpose of the study is to analyze the corporate social responsibility (CSR) activities carried out by Hindustan Unilever Limited (HUL). An empirical and analytical study was undertaken whereby the corporate official websites of the companies were analyzed. The most preferred CSR activities were observed to be women empowerment, self-employment, health hygiene and environment. The challenge for the companies is to determine a strong and innovative CSR strategy which should deliver high performance in ethical, environmental and social areas and meet all the stakeholders’ objectives.

Thara S Shetty Thara s shetty

Vendors on the streets: their situation and issues (with special reference of lucknow district, uttar pradesh)

Vending on the street is a worldwide fact and the most able to be seen component of the casual economy. Street vending, like other informal sectors, is characterised by low pay, ease of entrance, self-employment, and a huge number of individuals. Millions of individuals make a livelihood selling a variety of products and services on the street in cities and towns all over the globe. Despite the popular assumption that street selling would decline as the economy improves and wealth rises, it is on the rise in many areas. Because of their poor level of education and abilities, street sellers are often individuals who are not capable to get usual employment in the remunerative recognized sector. They attempt to address their financial issues by relying on their own limited financial resources. They are primary sharing route for a wide range of the daily-use goods, such as fruits, vegetables, ready-to-wear clothes, home appliances, stationery, toys, newspapers, magazines and shoes among others. If they be removed from the urban marketplaces, it would create serious problem for vegetable and fruit growers and small-scale businesses that couldn't afford to sell their goods via the formal sector's costly distribution networks. The significance of this industry can not be overstated, particularly given the government's inability to offer employment to India's millions of jobless and underemployed citizens. Even the corporate sector can only absorb a small part of our growing workforce. Overall, employment in the official sector is decreasing, leaving the majority of Indians to fend for themselves. If governments wish to decrease unemployment and poverty in our nation, they should support people in the informal sector to develop and thrive. They play an important part in the economic development and growth of local economy. Municipal authorities see street sellers as nuisances and the encroachers on sidewalks pavements and they are unappreciative of the important services that the street vendors offer to the world's common public. Vendors on the street offer essential services to urban people while surviving on their own business, limited resources, and labour. The state government and municipal authorities have been asked to provide security for street sellers so that they may make a living without fear.

Dr. Amarjeet Singh Dr. amarjeet singh

The anti-depressant activity of fixed oil of phaseolus vulgaris linn. in mice

Phaseolus vulgaris Linn commonly known as red kidney bean, is enriched in protein, carbohydrates and dietary fibres. Beans have nutritional and health benefits and possess antimicrobial, antihyperglycemic, antioxidant and anticancer activity due to bio-active chemical constituents. The following study was carried out to evaluate the anti-depressant activity of Phaseolus vulgaris fixed oil (PVFO) using a forced swim test and tail suspension test in mice. In this study, animals were assigned into four groups (n=7). Group I: Control normal saline (2 mL/Kg), Group II: PVFO I (2 mL/Kg), Group III: PVFO II (4 mL/Kg) and Group IV: standard amitriptyline (10 mg/Kg). The significant results indicated the possible anti-depressant role of Phaseolus vulgaris fixed oil.

Dr. Salman Ahmed Dr. salman ahmed

Antagonistic potential and plant growth promoting traits of achromobacter xylosoxidans isolated from tannery sludge sample

In the present study, the bacterium Achromobacter xylosoxidans was isolated from tannery effluent sludge sample in Dindugal, Tamil Nadu, India and screened for its bio-control efficacy against selected plant pathogens viz., Alternaria solani, Curvularia lunata and Fusarium oxysporum under in vitro. It was observed that maximum percent inhibition of mycelial growth of C. lunata (95%), followed by A. solani (85%) and F. oxysporum (80%). An attempt was also made for testing its plant growth promoting traits such as production of Indole acetic acid (IAA), phosphate solubilization efficacy, Hydrogen cyanide (HCN), ammonia and catalase production. Significant amount of plant growth promoting traits were noticed. Further studies on mechanism of bio-control against plant pathogens and plant growth promoting activities of Achromobacter xylosoxidans need to be conformed under in-vivo condition.

Dr. SARANYA DEVI K Dr. saranya devi k

Early diagnosis of tuberculosis using deep learning approach for iot based healthcare applications

In the modern world, Tuberculosis (TB) is regarded as a serious health issue with a high rate of mortality. TB can be cured completely by early diagnosis. For achieving this, one tool utilized is CXR (Chest X-rays) which is used to screen active TB. An enhanced deep learning (DL) model is implemented for automatic Tuberculosis detection. This work undergoes the phases like preprocessing, segmentation, feature extraction, and optimized classification. Initially, the CXR image is preprocessed and segmented using AFCM (Adaptive Fuzzy C means) clustering. Then, feature extraction and several features are extracted. Finally, these features are given to the DL classifier Deep Belief Network (DBN). To improve the classification accuracy and to optimize the DBN, a metaheuristic optimization Adaptive Monarch butterfly optimization (AMBO) algorithm is used. Here, the Deep Belief Network with Adaptive Monarch butterfly optimization (DBN-AMBO) is used for enhancing the accuracy, reducing the error function, and optimizing weighting parameters. The overall implementation is carried out on the Python platform. The overall performance evaluations of the DBN-AMBO were carried out on MC and SC datasets and compared over the other approaches on the basis of certain metrics.

Dr H Shaheen Dr h shaheen

Covid-19 and its implications in dental care

COVID-19 was first reported in Wuhan, Hubei Province of China a few months ago (December 2019) and had since become a major challenging public health problem for not only China but also many countries around the world. It was on March 11, 2020, characterized by WHO as a pandemic. The pandemic so far has killed more than 526,465 people and infected more than 11,046,917 people around the world as of 05 July 2020. Nigeria currently has 28,167 confirmed COVID-19 cases with 11,462 (40%) discharged, 16,071 (57%) currently receiving treatment at designated facilities across the country and unfortunately 634 (3%) deaths as at the time of writing this manuscript. As far as the authors are aware, there are little or no work carried out on the implications of COVID-19 on dental practices in Nigeria. Recently, COVID-19 was identified in saliva of infected patients and so transmission via aerosols and splatter generated during dental procedures is sure. To limit exposure, there was a need to avoid scheduling patients except for emergency dental care during this outbreak. This limitation on activities of the dental sector has a very huge impact on the economy of the sector as it has already resulted in serious monetary implications for dental practices worldwide. While dental practices in the high-income countries are getting help from their respective Government, those in the middle and low-income countries like Nigeria have been left to wallow in bankruptcy without support. The authors highly recommend that the Government of these neglected countries, step up and support dental practices that are on the brink of closing down due to the low turnout of patients to their practice during this outbreak.

Hope Inegbenosun Hope inegbenosun

Use of electronic resources among teachers and scholars in banaras hindu university, varanasi, uttar pradesh (bharat): a survey

The advancement of the information technology and web technology have brought changes to existing information storage and retrieval system such as Digital library, online database, digital repository, virtual library, etc. Libraries have witnessed tremendous changes in recent years in terms of their collection and services. Information explosion and user's demand of the users required the development of a more comprehensive library collection. Publishers have now started publishing on-line version/electronic versions of their printed journals. Owing to the cost of journals, many colleges and universities are unable to procure these journals. Ministry of HRD and UGC has started procuring the e-resources from the 25 world-class publishers under consortia mode at a much reduced price for all university libraries. BHU library is one of the beneficiaries of this UGC-INFONET Digital Library Consortium. The present study is the part of Ph.D. research work of one of the authors. To ascertain the usage of the e-resources available to the BHU library by the teachers and scholars, this survey was conducted. The present investigation discusses the use of electronic resources (e-journals, e-books, online/ offline databases, web resources) which are made available by the INFLIBNET Centre in eresource consortium like UGC-INFONET Digital Library Consortium by the teachers and scholars of BHU. The present study was conducted as a part of doctoral research work from January 2015 to July 2015.

Dr. Awadhesh Singh Gautam Dr. awadhesh singh gautam

A memetic algorithm for the inventory routing problem

In this article, we study an Inventory Routing Problem with deterministic customer demand in a two-tier supply chain. The supply chain network consists of a supplier using a single vehicle with a given capacity to deliver a single product type to multiple customers. We are interested in population-based algorithms to solve our problem. A Memetic Algorithm (MA) is developed based on the Genetic Algorithm (GA) and Variable Neighborhood Search methods. The proposed meta-heuristics are tested on small and large reference benchmarks. The results of the MA are compared to those of the classical GA and to the optimal solutions in the literature. The comparison shows the efficiency of using MA and its ability to generate high quality solutions in a reasonable computation time.

Mohamed Salim Amri Sakhri Mohamed salim amri sakhri

Wto, and its impact on higher education in global contxt

The cross line movement according to the two labor and products is the thing to take care of in the present worldwide economy. Worldwide exchange labor and products has for some time been a standard, for different advantages that gather from it. There have been numerous respective and multilateral arrangements comparable to cross line exchange dealings. The development of administrations area that decidedly influences the everyday daily routine and guidelines of experiencing or personal satisfaction. The World Trade Organization (WTO), of which in excess of 156 nations are individuals, has an understanding according to global administrations exchange. The General Agreement on Trade in Services (GATS) is the WTO's arrangement that administers exchange 12 sorts of administrations, including 'instruction administrations.Each WTO part that proposes to change its 'advanced education administrations' area to outline the 'responsibilities' by specifying certain conditions or restrictions with respect to its strategy on such progression. Contingent upon certain public or provincial targets and the states of interest and supply of advanced education, every part would set down various types of conditions while changing the area to unfamiliar instructive foundations. One of the basic inquiries or issues in such manner would be corresponding to the sort of college to be permitted to set up its grounds or branch or in any case offer training administrations. The inquiry raised here is should WTO individuals from Pro training Services Liberalization permit Foreign Private Universities or Foreign Public Universities?

Dr Gedam Kamalakar Dr gedam kamalakar

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