Hypertriglyceridemia-induced acute-pancreatitis (HTG-AP) is an important etiology of acute pancreatitis (AP). The treatment includes general management of AP with bowel rest, analgesia, and venous thromboembolism prophylaxis. Specific treatment of HTG-AP focuses on reducing serum triglyceride (TG) levels. Various modalities have been used, including heparin infusion, insulin infusion, plasmapheresis, and double filtration plasmapheresis (DFPP). However, the extent to which TG reduction translates into a clinical response remains unclear. This review highlights the emerging evidence on the management of HTG-AP. Insulin therapy and plasmapheresis remain treatment options to reduce TG. DFPP is an emerging treatment modality to reduce TG levels in patients with AP. However, to what extent this translates into a better clinical response is yet to be answered in large and prospective study designs.

Karishma

Background: Numerous studies have linked uterine fibroids to hypertension, suggesting that this condition may be a risk factor unique to women. These days, fibroids are the main cause of myomectomy and hysterectomy. This study aimed to ascertain the relationship between uterine fibroids and hypertension in Saudi women. Methods: This case-control study was carried out between January 2023 and January 2024 on patients with uterine fibroids and non-uterine fibroids who had an appointment for surgery at the gynecological department of the Maternal and Children Hospital (MCH) Sakaka, Aljouf, Saudi Arabia. Blood pressure readings and fibroid diameters are important factors in studying uterine fibroids. Results: The 140 individuals who were split into 70 cases and 70 control groups had average ages of 41.62±2.16 and 44±1.10. 95 participants had menorrhagia, which was the most common ailment in both groups. In contrast to the controls, the uterine fibroid cases had significantly higher rates of anemia (54.2%), OCP (12.8%), infertility (11.4%), and abortion (37.1%) (P<0.001). 48.5% of uterine fibroids had hypertension, compared to 17.1% of controls (P<0.001).Conclusion: There is a considerable relationship between uterine fibroids and hypertension. Anemia, infertility, and abortion are higher in uterine fibroid cases.

Karishma

The purpose of this study is to look at development trends and patterns of structural change in India's rural and labour markets. The rural labour strength have been moving from agricultural sector to non-agricultural sector for a living, after a long period of change (due to pain and growth-induced motives). Although the manufacturing sector lags, the building industry is a significant growing sector that employs rural people. Some improvements in rural areas have been made since the implementation of the MGNREGA rural employment development programme, but it has its own set of problems that experts are discussing. Furthermore, the rural labour market is plagued by high unemployment as a result of both the agricultural and non-farm sectors' failure to absorb rural employees. Nonetheless, the continuing COVID-19 epidemic has worsened its situation by causing a job-loss catastrophe. The rural labour market's future will become more unclear as a consequence of Covid pandemic-induced opposite migration of city workers to their villages, which has worsened food security and poverty issues in rural regions.

Dr. amarjeet singh

In the United States, prisoner reentry programs are a necessity to re-integrate back into society and are of two types: Faith and Non-Faith. With increased emphasis placed on reforming the criminal justice system policies due to Black Lives Matter and other non-profits actively working to change the system from the outside, reentry programs are having a resurgence of interest for effective public policy. There are significant barriers for major policies at the state, local, and federal to be alleviated, nevertheless, our research wanted to consider the effectiveness of five faith-based, male-only reentry programs in central Florida. Small focus groups were utilized to better understand the concerns and issues returning inmates faced in the program as well as when returning to society. Reentry participants were found to have high confidence in the success of their participation in their faith-based program’s efforts on their personal and family growth.

International journal of business and social science research

This research was conducted at Al-Baitul Amien Elementary School Jember which aims to answer the problem 1) How is the concept of prophetic education in shaping the character of students in Al-Baitul Amien Elementary School Jember? 2) How is the implementation of prophetic education in shaping the character of students in Al-Baitul Amien Jember Elementary School? 3) How is the evaluation of prophetic education in shaping the character of students at Al-Baitul Amien Elementary School Jember? The method used in this research is qualitative research methods. The approach used is a descriptive qualitative approach. The results of this study indicate: (1) The concept of prophetic education in shaping the character of students at Al-Baitul Amien Elementary School Jember, namely: the formation of a distinctive curriculum based on the historical values ??of the mosque, religious habituation programs, and the commemoration of Islamic holidays. (2) Implementation of prophetic education in shaping the character of students in Al-Baitul Amien Jember Elementary School, namely: Dhuha Prayers, Dhuhr and Asr Prayers in Congregation, Asmaul Husna Habits, Tahfidz Qur'an, Juz 30 Hafalan Program, Tartil Qur'an, Tilawati Qur'an (Qiro'ah), Friday charity, Islamic Studies, Team of action / affection, Learning the Koran, PAI Subjects, Learning Arabic, Student Liaison and Achievement Books, Commemoration of Islamic Holidays, Sholawat and Hadrah, Nasyid, and Da'i Little. (3) Evacuation of prophetic education in shaping the character of students at Al-Baitul Amien Jember Elementary School, namely: a connecting book for reports on the implementation of student sunnah prayers, compulsory prayer services, student morals at home, and also letters from parents to teachers and vice versa. Penelitian ini dilakukan di Sekolah Dasar Al-Baitul Amien Jember yang bertujuan untuk menjawab permasalahan, 1) Bagaimana konsep pendidikan profetik dalam membentuk karakter peserta didik di Sekolah Dasar Al-BaitulAmien Jember? 2) Bagaimana implementasi pendidikan profetik dalam membentuk karakter peserta didik di Sekolah Dasar Al-Baitul Amien Jember? 3) Bagaimana evaluasi pendidikan profetik dalam membentuk karakter peserta didik di Sekolah Dasar Al-Baitul Amien Jember? Pendekatan yang digunakan adalah pendekatan kualitatif deskriptif dan jenis penelitian lapangan (field research). Teknik pengumpulan data menggunakan wawancara, observasi, dan dokumentasi. Dan keabsahan datanya menggunakan triangulasi sumber dan teknik. Hasil penelitian ini menunjukkan: (1) Konsep pendidikan profetik dalam membentuk karakter peserta didik di Sekolah Dasar Al-Baitul Amien Jember yaitu: Kurikulum dibuat berdasarkan nilai historis masjid, program pembiasaan keagamaan, dan peringatan hari besar Islam. (2) Implementasi pendidikan profetik dalam membentuk karakter peserta didik di Sekolah Dasar Al-Baitul Amien Jember yaitu: melalui kegiatan Sholat Dhuha, Sholat Dhuhur dan Ashar berjamaah, Pembiasaan Asmaul Husna, Tahfidz Qur’an, Program Hafalan Juz 30, Tartil Qur’an, Tilawati Qur’an (Qiro’ah), Jum’at beramal, Kajian Islami, Tim penindak/ afeksi, Pembelajaran Al-Qur’an, Mata pelajaran PAI, Pembelajaran Bahasa Arab, Buku Penghubung dan Prestasi Siswa, Peringatan Hari Besar Islam, Sholawat dan Hadrah, Nasyid, dan Da’i Cilik. (3) Evaluasi pendidikan profetik dalam membentuk karakter peserta didik di Sekolah Dasar Al-Baitul Amien Jember yaitu: buku penghubung laporan mengenai pelaksanaan ibadah sholat sunnah siswa, ibadah sholat wajib, akhlak siswa dirumah, dan juga lembar surat dari orang tua kepada guru maupun sebaliknya.

Educare: journal of primary education

This study reviews indicators of poverty and the government policies and strategies to reduce and alleviate poverty in Jordan and investigate the effects of information technologies (ITC) on the poverty in Jordan, Population growth rate, GDP at current prices, consumer price index, and human development index in addition to percentage of population use internet, percentage of export and import of ITC of the total trade are used as dependent variables. Data from different resource is collected from 1999 in which the internet started in Jordan till 2018 on the abovementioned variables. The results show that there are negative impacts of the percentage of population using internet on the poverty rate while there are positive effects of human development index and consumer price index on poverty

Iaeme

Dermatophytes and Candida albicans are widespread with increasing prevalence and pose a grave threat to public health globally. Ocimum gratissimum and Mitracarpus scaber have been used in Southeastern Nigeria for several purposes, including antimicrobial effects, and have exhibited inhibition of growth to fungi. This study aimed to evaluate and ascertain the antifungal potential of these extracts against dermatophytes and Candida albicans. A total of 50 samples of dermatophytes and Candida albicans previously isolated from clinical samples at two different Hospitals, in the Southeast of Nigeria were used. The clinical samples were vaginal discharge, sputum, swab samples from the endocervix, urine, groin, mouth thrush, and palm. These organisms were all identified using standard mycological identification and characterization techniques. The sensitivity of selected fungi to the extracts (ethanolic extract of M. scaber and O. gratissimum oil) and ketoconazole was evaluated using a modified cup-agar diffusion plate method. The minimum inhibitory concentration (MIC) of the extracts was determined by the agar dilution method. Their minimum fungicidal concentration (MFC) and killing rates against the isolates were also determined. The organisms remain an important etiological agent in this species, implicated in several kinds of infections. The result showed that the activity of the O. gratissimum oil was comparable with that of the conventional drugs, indicating the potential in this extract. The MIC values for Candida isolates were consistently lower against O. gratisimum compared to ketoconazole. The MFC results indicated that O. gratissimum oil had a greater biocidal effect against most of the test organisms in contrast to ketoconazole. The killing rate study also indicated that the oil has very good activity against the isolates. O. gratissimum oil holds great potential for use in treating a wider spectrum of fungal pathogens.

Mediterranean journal of pharmacy and pharmaceutical sciences

Attempts have been made to formulate controlled release drug dosage forms using chitosan as a release controlling polymer. Granules of combination of chitosan, hydroxylpropyl cellulose, lactose, starch and Ibuprofen were prepared by wet granulation method using 1.0% lactic acid solution. The granules were physico-chemically characterized in terms of density, porosity, angle of repose, carr’s index and housner ratio and was found to be free flowing with good compressibility. FTIR spectroscopy was used and confirmed that there is no interaction between the drug and the added polymers. In vitro release of Ibuprofen, in phosphate buffer at pH 7.4, showed a steady and slow increase in the percentage of drug released over 24 hours as the percentage of chitosan was increased in the formulations compared to that from commercial tablets which released over 80.0% of their content in only two hours. The kinetic analysis using different mathematical models of the data revealed that the release kinetics of the drug form these formulations is somewhere between diffusion controlled, Fickian (anomalous) and non-Fickian which refers to a combination of diffusion and erosion controlled release. Thus, the high correlation coefficient of the data of drug release from most granules when zero order kinetics was applied revealed that there is a constant drug release with time for 24 hours.

Mediterranean journal of pharmacy and pharmaceutical sciences

Critical race theory (CRT) is an intellectual movement that seeks to understand how white supremacy as a legal, cultural, and political condition is reproduced and maintained, primarily in the US context. While CRT is part of a much longer research tradition investigating race and racism, which includes such key fgures as W. E. B. Du Bois, Frantz Fanon, Angela Davis, Audre Lorde, Gloria Anzaldúa, Cherríe Moraga, and many more, CRT distinguishes itself as an approach that originated within legal studies (in part building from and responding to critical legal studies); aims to be a vehicle for social and political change; has been adopted interdisciplinarily across many fields, including perhaps most notably education; and, in certain contexts, has come to be the umbrella term for studies of race and racism generally. CRT originated as an extension and critique of critical legal studies (CLS). It was also an outgrowth of Marxist critical theory that challenged the rationality, impartiality, and purpose of the legal system. According to the tenets of both CRT and CLS, the legal system is a political and ideological institution that, in part, rationalizes and justifies the existence of the state. Te legal system also requires mastery of an arcane and intentionally inaccessible vocabulary and a set of knowledge and power processes that limit ordinary people’s access to it. Te arbiters of law pretend to rely on reason but actually rely on subjective, politically motivated, culturally biased, and quasi-religious rationale for making and enforcing their decisions. CRT maintains the critique of legalistic thinking found in critical legal studies, but then adds a framework for understanding white supremacy as an immutable fact of a neocolonial state, as well as a praxis for changing it. What separates CRT from other forms of racial critique is that, “Unlike most of the earlier genres of race cholarship, critical race scholarship does not treat race as an independent variable; rather, it regards race as a site of struggle” (Orbe & Allen, 2008, p. 209).

Kamal singh

Hypoglycemia is a common complication of intensive diabetes mellitus therapy. This study was aimed to review the profile of admitted Libyan cases of non-pregnant adults and adolescents. A retrospective study for patients admitted to Tripoli Diabetes Hospital, Tripoli, Libya. Data were collected from medical files of diabetic patients with hypoglycemia from January 2017 to July 2018. Thus, during this period, a total of 29 cases with hypoglycemia were admitted to the hospital. Their age was ranged from 18 to 86 years in which 76.0% were female, 25.0% were non-smokers, 59.0% were married and 55.0% were non-employers. Patients with diabetes mellitus (86%) showed hypoglycemia attack per month of 3.90 ± 2.25. From the 25 cases with diabetes mellitus, 7.0% were newly diagnosed (> one year), 45.0% their duration of diabetes mellitus were more than 9 years and 35.0% were less than nine years. Their Hemoglobin A1C was on target (6.5–7.0%) in 21.0% of the cases, in which 17.0% were on below target range (< 6> 7.0%). 14.0% were on glibenclamide, 3.0% on glimepiride and 69.0% on insulin. Patients on insulin therapy twice daily in 28.0%, triple in 17.0% and basal bolus regime in 24.0%. Hypoglycemia unawareness was presented in 17.0%, hypoglycemia was major in 45.0% of the cases, and in 38.0% were in daytime. Insulin induced hypoglycemia were in 66.0%, and suicidal attempt were in 10.0%. Exercise induced hypoglycemia 10.0% and 3.0% of cases with malignancy induced hypoglycemia. Co-exist systemic illness was mainly absent in 69.0% but cardiovascular diseases in 14.0% and renal diseases in 7.0%. Majority of cases were discharged in good condition (86.0%) and 14.0% discharged against medical advice. Hypoglycemia mostly occurs in patients with diabetes mellitus treated with insulin and in most the cases were reversible and saved with good management. Thus, patient education is a fundamental issue in prevention and reducing complications of hypoglycemia in patients with diabetes mellitus.

Mediterranean journal of pharmacy and pharmaceutical sciences

Wilsons disease is a rare inherited disorder which is characterized by impaired copper excretion which leads to excessive deposition of copper in many tissues and organs like brain, liver, and eye. This is also characterized by Kaiser-Fleischer ring, low serum ceruloplasmin levels and elevated urinary copper excretion [1]. A 26year male patient came to the neurology department with chief complaints of involuntary tremors of both hands and difficulty in walking in the last one month associated with swaying to one side in the last 20 days. On examination the patient is having Kaiser-Fleisher ring positive and upon further investigation Magnetic resonance imaging brain was performed which revealed the features in favor of Wilson’s disease. And for this condition the patient is treated with chelating agents and benzodiazepines.

Dr venkata rama rao nallani

The seeds of Cleome viscosa are used in traditional systems of medicine for the treatment of many diseases in Asia. This study evaluated fixed oil from the seeds of Cleome viscosa for analgesic and antiemetic activity by using the acetic acid induced writhing test in mice (intraperitoneally) and chick emetic model (oral treatment) respectively. The results showed significant analgesic and antiemetic activities of Cleome viscosa fixed oil.

Dr. salman ahmed

Introduction: Psilocybin mushroom use is well documented in spiritual and religious ceremonies globally. This drug is now the most popular in Europe and the USA. Objective: The objective of this study is to explore the experiences and effects of psilocybin on patients with depression and anxiety. Method: A qualitative study was conducted interviewing ten participants currently taking psilocybin while experiencing depression and/or anxiety. Ethical approval was obtained from the University ethics committee. Participants were recruited via social media and groups are known to have used psilocybin for the treatment of anxiety and/or depression. Participants were informed of study aims and consent was obtained before interviews commenced. Confidentiality was maintained throughout this study. Interviews began with informing participants that psilocybin may be effective in the management of depression. Initially, information around the way treatment with psilocybin was obtained was sought. This was followed by queries around the effects of the drug in terms of experiences both during and after treatment. Finally, participants were asked to outline the positive effects of psilocybin on their lives. Results: The data were thematically coded using Grounded Theory as an underpinning philosophical paradigm. Emerging themes included enhancement of smell, vision, hearing, and taste sensations. Another theme emerging was the experience of being ‘connected with the universe’ while on the drug. Additionally, participants reported a stabilization of mood, an increase in optimism and emotional control, and a healthier emotional connection with others. Most also felt an increase in comfort, peace and calmness. Another theme that emerged centered on the mechanism of action of psilocybin. Participants stated that this substance seemed to ‘make new connections in their brain,’ resulting in new perspectives. Some participants felt this resulted in a calming influence on the mind and body. This aligns with research showing that psilocybin works by changing the thinking and improving information processing. Conclusion: Psilocybin has promising effects on the patients with depression/anxiety even after a single dose. Psilocybin is safe but the administration should be guided by a health professional to yield safe and positive outcomes.

Gwen erlam

The concept of knowledge and the process of knowledge sharing in ethnic minority microbusinesses remain neglected in contemporary debates even if their role for economic development is recognized. Drawing on a culturalist view, we explore how knowledge is defined and shared in a local niche market. Thematic analysis of semistructured qualitative interviews with 32 owner managers and 11 employee-managers reveals that, contrary to studies on larger firms, local knowledge creation and sharing narrowly based on ethnic strengths are valuable sources of competitive advantage. Our study has implications for researchers, policymakers, and practitioners in exploring, supporting, and integrating ethnic minority microbusinesses.

Muhibul haq

A simple, precise, accurate, sensitive, specific and reliable stability indicating RP-HPLC method was developed for the simultaneous estimation of Miconazole (MIC) and Ornidazole (ORN) in pharmaceutical dosage form. The method was developed with mobile phase containing buffer (0.05M potassium dihydrogen ortho phosphate, ph3.5): Methanol in the ratio of 25:75, C18 (250 x 4.6mm, 5µm) as a stationary phase and flow rate was 1 ml/min. Detection was carried out at 236nm in UV-2000 detector. The selected chromatographic conditions were found effectively to separate Miconazole and Ornidazole at 6.58 and 3.26 min respectively. The proposed method has been validated for precision, accuracy, robustness. Thus, the statistical analysis confirms that developed methods were successfully used for analysis of formulation and thereby can be used for routine analysis of drugs in Quality Control laboratories.

Prachi barbhaiya

The recent boom in Android mobile device usage has caused a shift in the information technology and has affected the way how information and data are stored, shared among the mobile users. The advent of social networking applications also demands the availability of resources that can be shared among the authentic users. This paper reviews and compares the available techniques and solutions for detecting Unexpected Permission Authorization to Mobile Apps. It is observed that malware for the android system is also growing significantly, current solutions for detecting malware on smartphones are still ineffective.

Manisha patil

Project management plays significant roles to the success of the project. The aim of the study is to review and analyze latest literature on the effects of triple constraints on the project outcome. The study is based on the secondary method whereas literatures are collected form the google scholar ranging from 2010 to 2023. After reviewing the literature, the study concludes a number of findings. The quality of the project is highly depended on the time and budget. However, inadequate management, stakeholders involvement are also play crucial roles towards project success. The study concludes a number policy recommendations.

Nazim ullah

Kidney mass lesions are common and are often discovered accidentally. Renal cell carcinoma (RCC) represents approximately 5% of all cancers. Men have a two-fold higher likelihood of developing the disease and experience a higher mortality rate than females. The differences between the genders are attributed to individual variations, including hereditary factors, underlying medical conditions, genetics, lifestyle, hormonal factors, and others, such as hypertension and obesity. Renal tumors are usually asymptomatic; however, hematuria, dull aching flank pain, and lower abdomen pain can present symptoms. A tissue biopsy is typically unnecessary but may be required in certain cases. Men tend to exhibit larger and more severe tumors. Radiology tools application is helpful for early diagnosis and follow-up. Partial or radial nephrectomy is an effective curative therapy in localized renal masses. Nevertheless, immunotherapy, cryotherapy, and sometimes chemotherapy are used, especially in high-income nations. In this review, epidemiology, pathophysiology, risk factors, presentation, diagnosis, and kidney mass management will be reviewed and updated. Different keywords and phrases, such as kidney malignancy, renal cancer, epidemiology of kidney cancer, nephrectomy in kidney masses, and management of renal cell tumors, were used to search PubMed, EMBASE, Scopus, Google, and Google Scholar for new reviews and original articles and new comments with updates that were published between January 2019 and May 2025.

Karishma

The seed flours of Macrotyloma uniflorum (Lam.) Verdc., Phaseolus lunatus Linn., and Phaseolus vulgaris Linn. were investigated for their total, soluble and insoluble oxalate contents by HPLC. The total oxalate content of Macrotyloma uniflorum, Phaseolus lunatus and Phaseolus vulgaris were 1.24, 1.77 and 1.71 mg/ g, respectively. The % age of soluble oxalate was Macrotyloma uniflorum (19.50), Phaseolus lunatus (15.08) and Phaseolus vulgaris (15.88). The calculated soluble oxalate: calcium ratio of all tested legume flours is lesser than one and hence will not create any resistance in calcium bioavailability.

Dr. salman ahmed

Aim: To evaluate the hepatoprotective activity of the chloroform extract of the selected Glinus lotodies linn plant by using Paracetamol induced hepatic injury in albino rats. Methods: The chloroform extract of Glinus lotodies linn was allowed for screening hepatoprotective activity on Paracetamol induced Albino rats and they were compared with standard and negative control. Results: The drug treatment Chloroform Extract of Glinus lotodies linn [CEGL] was carried out at two low dose levels 200mg and 400mg/ kg, both of which along the standard Silymarin 100mg/kg treated group showed a significant reduction in the elevated enzyme levels (P < 0.01). Liver section shows normal cells compared to control. Conclusion: These data suggests a dose dependent hepatoprotective activity of CEGL. At the end of this study, a strong conclusion can be drawn that the Chloroform Extract of Glinus lotoides linn possess hepatoprotective activities induced by Paracetamol in Albino rats.

Sudha rameshwari.k assistant professor