Novel grading system for horizontal fissure of right lung based on cadaveric study of north indian population

Introduction: The right lung has two fissures, an oblique and a horizontal, dividing it into three lobes namely the upper, middle, and lower. The nature of the fissure is of great importance in planning operative strategy for thoracoscopic pulmonary resection where an the incomplete fissure may contribute to post-operative air leakage Aim: To assess the gross morphological features of the right lung with special emphasis on the completeness of horizontal fissure. Material & Method: Material for the present study comprised of right lungs obtained from 50 well-embalmed adult human cadavers of both the sexes dissected as a part of 1 MBBS curriculum in the Department of Anatomy, Govt. Medical College, Amritsar. Results: Horizontal fissure was found to be complete in only 10% of the lungs while in rest 90% it was either incomplete or absent. Conclusion: Inferable from the huge variation in nonappearance or partial appearance of horizontal fissure in the right lung and to the absence of an acceptable classification of fissures, an endeavor has been made to give one such classification. In like manner, the horizontal fissure is evaluated from Grade zero to IV contingent on its absence and profundity from coastal surface to the hilum. Each evaluation is additionally divided into 3 subgrades relying on the culmination or incompleteness of these fissures with respect to their length.

Dr kulbir kaur

Morphological and chemical traits associated with resistance against spotted pod borer, maruca vitrata in pigeonpea

Host plant resistance is an important tool for minimizing the losses in pigeonpea due to spotted pod borer, Maruca vitrata, which is the most threatening hidden pest of pigeonpea crop. Experiment was carried out to study the morphological and chemical traits in pigeonpea associated with expression of resistance to M. vitrata and their incidence in different sowing dates. The incidence of M. vitrata varied significantly among different sowing dates. Crop sown on D2 (1st week of July) resulted in maximum pod infestation by M. vitrata (13.1%). Minimum pod infestation (2.3%) and (2.9%) was recorded in D4 (3rd week of July) and D1 (3rd week of June) sown crop, respectively. Among different varieties, AL-201 registered lowest pod infestation (4.3%) as compared to Pusa-992 (7.9%). The non-glandular (type A), and glandular (type B) pod trichome density of top, middle and lower canopy of the plant and the pod wall thickness was responsible for the resistance to M. vitrata. Whereas, non-glandular (type C) pod trichomes, pod length, seed width and number of seeds per pod were associated with the susceptibility to spotted pod borer. Expression of resistance to M. vitrata pod infestation was associated with low amounts of crude protein and total soluble sugar and higher amount of fat content, phenol content and tannin content of seed as well as pod wall

DR. BABU LAL JAT Dr. babu lal jat

Business law

The United Kingdom (UK) is a constitutional monarchy where the Head of State is currently the Queen (part of the monarch) rather than the president. The roles, functions, and power are considered via convention, among them being that the monarch should be neutral politically (Bodleian Libraries 2021). The UK has three legal systems for England and Wales, Scotland, and Northern Ireland (Rab 2021). The former two nations use the common law system combining the approval of legislation by parliament, which includes the Monarch, House of Commons, and House of Lords, and the creation of precedents via case law (Rab 2021). The House of Commons is elected the population, with the Prime Minister being a traditional member of the House (Rab 2021). On the other hand, the judiciary is appointed to control the Court System and case law and is separate from the Parliament (Bodleian Libraries 2021). However, these systems are the UK law emanating from applicable laws to the UK, including its citizens. The UK law is summarized in the concept map highlighting the different types of laws governing the UK

Zamzam Abdelazim Zamzam abdelazim

Behavior of small states from the perspective of international relations theory: an analysis of south china sea

Territorial disputes in the South China Sea have long been one of the most critical and complex issues of security between south-east Asian states and China. The competition for maritime rights has emerged as the most important security issue in the east Asia. The powerful states have a tendency for domination. The smaller states may not show their dominating behavior over other states, but they have tendency to maximize their relative power by making alliance with great power or by other means. Since the smaller states are not capable enough individually to ensure their own security or to use military force against threatening power, they have tendencies to join in alliances or in other words to create balance of power to ensure their own security. This study attempts to analyze the behavior of small states and to find out which theory matches with the behavior. The behavior of small states like Vietnam and the Philippines cannot be well-explained by the realist approach. They behave to make their existent clear and safeguard themselves only. Making allies with great powers as well as economic ties simultaneously with other economic powers render their behavior of having peaceful coexistent with everyone.

Muhammad faruq-uz-zaman

Professional values, ethics, and professionalism of public relations practitioners

This study explores the influence of education, length of service, professionalism, and ethics on the professional values of public relations practitioners in Malaysia. A total of 427 questionnaires were distributed to public relations practitioners in Malaysia, and 322 questionnaires were returned. The study included 61% female respondents, and 39% male respondents. The study analyzed and identified the influence of professionalism and ethics on professional values of public relations practitioners. Additionally, the study examined whether education and experience influence professional values through professionalism, and code of ethics. Six hypotheses were tested to answer the research questions. The results from this study fully supported the hypotheses indicating that professionalism and ethics had an influence on professional values of public relations practitioners. The results also showed that education influenced both professionalism and ethics, and length of service influenced both professionalism and ethical practice.

Mohammed Fadel Arandas Mohammed fadel arandas

Will comprehensive sexuality education (cse) help in youth development?

Purpose – The purpose of this review is to critically analyse the extant research and help readers understand the ways the school-based comprehensive sexuality education (CSE) can contribute towards youth development and urge policymakers to implement nationwide good-quality, scientific, culturally relevant, age-appropriate and holistic school-based CSE. Design/methodology/approach – This literature review has been designed using the extant information available on Google Scholar, Web of Science (WoS) and PubMed. Findings – The findings of this review inform that there is a significant need amongst the youth of the day for good-quality, scientific, culturally relevant, age-appropriate and holistic school-based CSE. Also, the findings suggest that there are significant associations between school-based CSE and youth development. Research limitations/implications – This research paper although draws from extant literature about sexuality education and its delivery across the globe, it applies the sexuality education scenario in India. Practical implications – The findings of this review aim to implicate nationwide policy-level changes to implement CSE in the school curricula. There are more practical behavioural changes that CSE could foster amongst students, which are discussed in the review. Social implications – Due to the behavioural changes that CSE could foster amongst students, it may help in the upbringing of responsible citizens who are free of health complications, who can make independent health related decisions and look after each other in the community. Originality/value – This review is an original contribution from the author. Whilst there is extant literature about CSE and youth development, this article fills the void by investigating the interdependent contributions that both the concepts can make to one another and encourages more research on this topic.

Hari hara sudhan r

Pharmacotherapy and associated risk factors for pulmonary tuberculosis

Tuberculosis is communicable disease which is common and often deadly infectious disease caused by mycobacterium tuberculosis. Tuberculosis continues to be a major public health problem in the world. The aim of this study is to assess prevalence and associated risk factors of pulmonary tuberculosis. Treatment and development of multidrug-resistant tuberculosis were also considered. Drugs for Pulmonary tuberculosis confirmed cases used in calculating tuberculosis prevalence in Libya which is obtained from archive department of Abu Seta Hospital. Data obtained from 427 files during 2019 determine the incidence and epidemiology of tuberculosis in Libya. For a total of 427 confirmed cases of pulmonary tuberculosis, about 75.0% of the cases were male and most of the patients (55.0%) were within the age group of 20 - 40 years old. Of the study patients, 114 patients (26.7%) were viral infected and most of the viral infected cases were in the age group of 20 - 40 years and the majority of this age group patients (n = 41, 53.2%) were infected with HIV/HCV, while the least percentage in this group age were infected with HIV/HBsAg (01.3%). Among 427 cases, 73 cases (17.1%) were comorbid with other chronic diseases. Of the 73 cases, 54 cases (74.0%) were diabetes mellitus whereas only 1.4% of them had bronchial asthma, Parkinsonism and renal failure. The drug therapy of active tuberculosis disease needs combination chemotherapy to escape the selection of naturally occurring drug-resistant mutants. Amongst current anti tuberculosis drugs, the rifamycins hold the highest potential for shortening treatment and improving effects. Prevalence of smear positive tuberculosis and bacteriologically confirmed that a high rate of tuberculosis among unemployed population. This study reported that the highest incidence rate is found in people who are smokers.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

Two-stage rfid approach for localizing objects in smart homes based on gradient boosted decision trees with under- and over-sampling

eveloping automated systems with a reasonable cost for long-term care for elders is a promising research direction. Such smart systems are based on realizing activities of daily living (ADLs) to enable aging in place while preserving the quality of life of all inhabitants in smart homes. One of the research directions is based on localizing items used by elders to monitor their activities with fine-grained details of the progress. In this paper, we shed the light on this issue by presenting an approach for localizing items in smart homes. The presented method is based on applying machine learning algorithms to Radio Frequency IDentification (RFID) tags readings. Our approach achieves the required task through two stages. The first stage detects in which room the selected object is located. Then, the second one determines the exact position of the selected object inside the detected room. Additionally, we present an efficient approach based on gradient boosted decision trees for detecting the location of the selected object in a real-world smart home. Moreover, we employ some techniques of over- and under- sampling with data clustering for improving the performance of the presented techniques. Many experiments are conducted in this work to evaluate the performance of the presented approach for localizing objects in a real smart home. The results of the experiments have shown that our approach provides remarkable performance.

Shadi Abudalfa Shadi abudalfa

Awareness and knowledge about refractive errors and strabismus in south indian population

Background: To assess the awareness, knowledge about refractive errors and strabismus among the general public in southern Indian states of Andhra Pradesh and Telangana. Methods: A cross sectional population-based survey used a semi structured questionnaire on awareness, knowledge on refractive errors and strabismus done as part of knowledge, attitude and practices study (KAP). Stratified multistage cluster random sampling method was used with a sample size of 867 adults- ≥16 years. Having heard of refractive error and strabismus was defined as awareness and having knowledge of the type of error for which spectacles were worn, was considered as knowledge. A pilot study was conducted to validate the questions used in the main study. Statistical package SPSS (version 19) was used for analysis to calculate logistic regression and odds ratios for gender, age, education and urban-rural areas. Results: A total of 782/867 (90.1%) subjects participated in the survey with females 47.4%. 581 subjects (74.3%) were aware of refractive error. 690 subjects (88.2%) were aware of squint. With multiple logistic regression about awareness of refractive error to various variables, subjects who were educated 11th class to degree had a higher awareness (OR: 2.40; CI: 1.25-4.60). With multiple logistic regression about awareness of squint to various variables, females had a higher awareness of squint (OR: 1.98; CI: 1.19-3.31). Conclusions: Awareness of squint and refractive error was high among the general public, but the knowledge of it was limited.

srinivasa reddy pallerla Srinivasa reddy pallerla

A study on the cause of stress among employees in private banking sector

Purpose of this study is examining the cause of stress among selected private banking employees. Stratified sampling method was used to carry out the data collection. For this employee of various private banks were chosen. A questionnaire with 12 items with dichotomous (Yes-1, NO-2) were developed and tested for reliability and prior to the distribution of questionnaire. 253 respondents were selected from various private banks in Mysore district, Karnataka state India. The survey questionnaire was sent via email, requesting to complete it. The questionnaire includes 11 demographic information’s and statements to measure. Chi-Square analysis was carried out to examine the cause of stress among employee using SPSS21. We found that designations have significant influence on employee and The other factors of do not have any significant influence on employee. Therefore we concluded that in private banks demographic variable such as designation creates stress in all aspects. Future research should consider a larger sample from leading sectors where job natures are similar. Analysis should be more rigorous, where Amos could be used for analysis.

Dr MANJUNATHA M K Dr manjunatha m k

Treatment possibilities for acquired and hereditary diseases by gene therapy: a review

Therapeutic nucleic acids demand specificity and accuracy in design as well as delivery strategies used in replacement or silencing of the target gene. Gene therapy is believed to be the therapy in which the root cause of the diseases can be treated at the molecular level. Generally gene therapy helps in the identification of the origin of the disorder instead of using drugs to diminish or control the symptoms. The application of nucleic acids to treat and control diseases is known as “gene therapy.” Gene therapy consists on the substitution or addition of a functional gene into the nucleus of a living cell, in order to treat a disease or repair a dysfunction, caused by this gene failure. This therapy is used to correct defective genes, which are responsible for genetic diseases. Thus, gene therapy can be used to prevent, treat or regulate hereditary or acquired disorders, by the production of therapeutic proteins. The gene therapy is mediated by the use of viral and non-viral vectors to transport foreign genes into somatic cells to restorative defective genes. This review focuses on viral vectors in detail.

Dr.P.V.Kamala Kumari Dr.p.v.kamala kumari

Inhibition of hyperoxaluric calcium oxalate nephrolithiasis by macrotyloma uniflorum (lam.) verdc. seeds infusion on glass slide

Hyperoxaluria is a metabolic disorder responsible for calcium oxalate nephrolithiasis. The study was conducted on glass slides to observe the growth patterns of urinary calcium oxalate monohydrate crystals and their inhibition by 5, 10, 15 and 20 % infusion of Macrotyloma uniflorum seeds. For this purpose, a drop of gel medium (sodium metasilicate of 1.06 specific gravity and 3M acetic acid solution) at pH 5.02 - 5.17 was placed in the middle of a glass slide and converted into a gel. A 1 M oxalic acid drop was dropped to the left, and 1 M calcium chloride and magnesium acetate (1:1) solution was dropped to the right side of the properly formed gel. The glass slide was observed under a microscope till it was completely dried. In the case of the crystal inhibition study, a drop of M. uniflorum infusion was also added on the right side just after adding calcium chloride and magnesium acetate solution. The results without infusion showed detailed morphology and aggregation patterns of observed crystals such as donut, dumbbell, needles, platy, prismatic, rosette, round edges, X-shape crystals, loose and compact aggregates. All infusions of M. uniflorum affected the crystals, forming defective crystals. 5 % infusion inhibited crystals of all morphologies except donuts, X-shaped crystals, donuts, platy crystals and rosettes. Defected rosettes were observed in 10 % infusion, which was reduced gradually in the crowd by 15 and 20 %, respectively. From this study, it can be concluded that M. uniflorum seeds infusion is effective against calcium oxalate nephrolithiasis.

Dr. Salman Ahmed Dr. salman ahmed

India’s trade growth: a comprehensive analysis of import and export

India’s economic system has undergone significant changes in recent years reflecting globalization and changes in national policies. This paper provides a comprehensive analysis of India’s economic growth, focusing on imports and exports. The study explores the key drivers of economic expansion, including trade liberalization, trade agreements, and technological advancement. It also explores the impact of international trade and geopolitical events on business models. It assesses the role of policy measures such as the Goods and Services Tax (GST), the Make in India initiative, and various free trade agreements in generating economic benefits. The paper also assesses the trade balance and its impact on India’s economic stability and growth. The paper concludes with recommendations for improving the market, including diversifying entrepreneurs, investing in infrastructure, and strengthening the domestic economy. The review provides insights to policymakers, businesses, and academics who want to understand and harness India’s economic potential in the global economy

Dr Gedam Kamalakar Dr gedam kamalakar

Evaluating the effects of insulin, metformin and glibenclamide on the pups’ prefrontal cortex and oxidative stress markers of streptozotocin-induced diabetic pregnant rats

There is an upsurge in gestational diabetes mellitus with many devastating consequences for the mother and developing fetus. Insulin therapy remains a mainstay. However, insulin is expensive and comes with the pain of multiple injections. Therefore, there is a need to explore commonly administered oral hypoglycemic agents to cater for the increasing gestational diabetes mellitus-associated neurological complications. This study assesses the effects of glibenclamide, metformin and insulin on the pups’ prefrontal cortex in diabetic pregnant rats. 35 sexually matured adult female rats weighing between 120 g and 160 g were used and assigned into five groups (A to E) of seven rats each group. Diabetes was induced by streptozotocin (45 mg/kg and 35 mg/kg; ip). Hyperglycemic rats were treated with insulin (1.0 UI daily), metformin (200 mg/kg/day) and glibenclamide (0.6 mg/kg/day). Body weight and blood glucose levels were evaluated. Rats were sacrificed at 18-day gestation, the pups were harvested, and their brains were processed for tissue oxidative stress markers and various histological examinations. Glibenclamide and metformin caused a significant blood glucose reduction at 37.9% and 40.7%, respectively, compared to the insulin group (33.09%). There was no significant difference in the body-organ ratio in rats treated with metformin when compared to rats treated with insulin. Metformin and glibenclamide had a significant increase in tissue glutathione reductase and a decrease in malondialdehyde compared with insulin and diabetic control groups. The pups’ prefrontal cortex showed degenerated neuronal cells in the diabetic control animals. The diabetic rats treated with metformin and glibenclamide showed improved pyramidal neurons compared with diabetic and insulin groups. This study suggests that metformin and glibenclamide glycemic control may prevent and improve antioxidant enzymes and reverse some neurotoxic effects caused by streptozotocin-induced diabetes in rats.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

Analgesic activity of leaves, flowers and fruit peel of luffa cylindrica (l.) roem.

Ethanol extracts of leaves, male flowers and fruit peel of Luffa cylindrica (L.) Roem., were evaluated for analgesic effect using the analgesy meter test, a mechanically induced pain model. Extracts at 500 mg/kg, p.o., were tested and compared with diclofenac sodium 50mg/kg as a standard analgesic drug. The mechanical force was applied to the rat's paw and continuously increased. The point at which the rat can’t bear further pressure and starts to struggle to free the paw was taken as a nociceptive response. Readings were taken before and after 1, 2 and 3hr following drug administration. The analgesic response was continuously increasing till 3hrs. Tested extracts produced significant and comparable analgesic effects as with diclofenac sodium.

Dr. Salman Ahmed Dr. salman ahmed

Comparison of oxygenation and ventilation parameters between proseal laryngeal mask airway and endotracheal tube in patients undergoing laparoscopic surgeries: a prospective observational study

Introduction: Use of endotracheal tube (ETT) has many limitations. There is a need for an airway device with similar safety and good side effect profile. In this prospective observational study, the oxygenation and ventilation parameters between patients who were inserted Proseal laryngeal mask airway (PLMA) or ETT for laparoscopic surgeries were compared. Materials and Methods: After ethical committee approval, informed consent was obtained from sixty patients (thirty in each group) posted for elective laparoscopic surgery. Following induction of general anaesthesia and paralysis, PLMA or ETT was inserted and pressure control mode was used for ventilation. The following parameters were measured: a. Oxygen saturation and changes in FiO2 needed to ensure a target SpO2> 95%, EtCO2 and changes in respiratory rate and inspiratory pressure needed to ensure a target EtCO2 between 35-45 mmHg. b. Insertion characteristics of airway device and gastric tube, hemodynamic responses, incidence of complications. Statistical Analysis: Chi-square test was used to analyze qualitative data. Independent t test was used to assess quantitative variables. Repeated measures ANOVA was used to compare the outcome measures over time adjusted for duration of surgery and anaesthesia. P values<0> Results: Both groups were comparable with respect to age, gender and weight. Oxygenation and ventilation parameters achieved with both ETT and PLMA were comparable and satisfactory. Haemodynamic parameters increased significantly in ETT group compared to PLMA group during airway insertion and removal. Also, postoperative sore throat was comparatively less in the PLMA group. Conclusion: Hence we conclude that PLMA may be considered as an alternative to ETT in airway management of patients undergoing laparoscopic surgeries with comparable oxygenation and ventilation parameters and improved side effect profile.

Kamal Singh Kamal singh

Evaluation of the antifungal efficacy of mitracarpus scaber extracts and ocimum gratissimum oil against clinical isolates of fungi

Dermatophytes and Candida albicans are widespread with increasing prevalence and pose a grave threat to public health globally. Ocimum gratissimum and Mitracarpus scaber have been used in Southeastern Nigeria for several purposes, including antimicrobial effects, and have exhibited inhibition of growth to fungi. This study aimed to evaluate and ascertain the antifungal potential of these extracts against dermatophytes and Candida albicans. A total of 50 samples of dermatophytes and Candida albicans previously isolated from clinical samples at two different Hospitals, in the Southeast of Nigeria were used. The clinical samples were vaginal discharge, sputum, swab samples from the endocervix, urine, groin, mouth thrush, and palm. These organisms were all identified using standard mycological identification and characterization techniques. The sensitivity of selected fungi to the extracts (ethanolic extract of M. scaber and O. gratissimum oil) and ketoconazole was evaluated using a modified cup-agar diffusion plate method. The minimum inhibitory concentration (MIC) of the extracts was determined by the agar dilution method. Their minimum fungicidal concentration (MFC) and killing rates against the isolates were also determined. The organisms remain an important etiological agent in this species, implicated in several kinds of infections. The result showed that the activity of the O. gratissimum oil was comparable with that of the conventional drugs, indicating the potential in this extract. The MIC values for Candida isolates were consistently lower against O. gratisimum compared to ketoconazole. The MFC results indicated that O. gratissimum oil had a greater biocidal effect against most of the test organisms in contrast to ketoconazole. The killing rate study also indicated that the oil has very good activity against the isolates. O. gratissimum oil holds great potential for use in treating a wider spectrum of fungal pathogens.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

Determination of the rich structural wave dynamic solutions to the caudrey–dodd–gibbon equation and the lax equation

This article addresses the implementation of the new generalized (G'∕G)-expansion method to the Caudrey–Dodd–Gibbon (CDG) equation and the Lax equation which are associated with the fifth-order KdV (fKdV) equation. The method works well to derive a variety of standard and functional closed-form wave solutions with distinct physical structures, such as, soliton, kink, periodic soliton, and bell-shaped soliton solutions. The solutions obtained using this method are useful and adequate than other methods. In order to understand the physical aspects and importance of the method, the attained solutions have been simulated graphically. The extracted results definitely establish that the new generalized(G'∕G)-expansion method is an effective mathematical tool to work out new solutions to different types of local nonlinear evolution equations emerging in applied science and engineering, but this method is not effective in solving nonlocal equations.

Md khorshed alam

Impact of environment due to sars-cov-2 in india

Before the start of the SARS-CoV-2 (COVID-19) pandemic, the whole environment around us had been deemed very toxic to breathe in due to the amount of greenhouse gases that had been emitted over the centuries. The Earth faced rising temperatures, which in turn led to the melting of glaciers and rising of sea levels. Environmental degradation was happening fast due to the depletion of resources such as air, water and soil. But after the coronavirus lockdown (Talabandi) commenced, there have been changes in the environment. The lockdown still has a huge impact on people in India too. The halt of industrial production and traffic resulted in cleaner air and rivers. In India the first phase of the nationwide lockdown that began on March 24 followed by enforcement of a series of regulations had some evidences that the COVID-19 curve is flattening in the country's COVID-19 affected regions. There was a good chance Prime Minister Narendra Modi extended the lockdown (Talabandi) four times that ended on (Phase 1 (24 March-14 April)., Phase 2 (15 April-3 May)., Phase 3 (4 May-17 May) & Phase 4 (18 May-31 May). The paper focuses on different aspects of environmental impact due to SARS-CoV-2 in India.

Rina Kumari Rina kumari

Review on non-destructive testing of composite materials in aircraft applications

The increasing usage of composite materials has immersed simpler techniques for inspecting the integrity of composite structures, as composite materials typically have probability of getting material imperfections. In non-destructive testing, shearography reveals defects in associate object by distinguishing defect-induced deformation anomalies. Non-destructive testing (NDT) methods skit and streamer role in physical characterization of new composite materials and in assessment of their quality and serviceability in structures. Non-destructive testing (NDT), Non-destructive inspection (NDI), and Non-destructive evaluation (NDE) are concerned with the techniques and measurements that provide data on the condition of the materials and structures at the time of manufacturing and in-service.

Boopathy Govindarajan Boopathy govindarajan

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