Human resource management is critical for hospitals but is frequently disturbed by employee retention issues. This research aims to determine the influence of compensation, organizational commitment, and work motivation on employee retention at Malahayati Medan. The research method applied is quantitative research by collecting data through questionnaires distributed from July to October 2022. The sampling method used is purposive sampling, with 78 employees as the sample. The data analysis method used is descriptive statistics, coefficient determination, multiple linear regression analysis, and hypothesis testing with t-test and F-test. The results of the t-test are compensation, organizational commitment, and work motivation partially influence employee retention. The results of the F test showed that all independent variables simultaneously influence employee retention and 61.1% of employee retention is influenced by compensation, organizational commitment, and work motivation. It is recommended for companies in similar industries pay attention to the results of this research.

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Cystic fibrosis is a challenging disease which creates many complications. The impact caused from cystic fibrosis on an adolescent is a challenging phase for their lives. Negative impacts like the society’s pressure, anxiety and depression are few common reasons that are being unspoken and ignored due to complexity of the disease. This study is aimed to identify the necessary gaps and educate the necessary policy makers and CF center health care team to have a better understanding about the context of the aftermath of cystic fibrosis and enhance better patient care. More over this systematic review also points out the main trends in this field of study. Qualitative study and quantitative are prominently used research methods to gain an understanding the about the gaps in the research. However, there is still a scarcity of quantitative and mixed research methods. Furthermore, limitations such as language, cultural influences were identified whilst going through the analysis. Overall through the information given in the following in this study more information regarding that warrants answers can be identified which will lead to proper care towards the teenagers who suffers from cystic fibrosis

Chanitha pemasena

Though the anatomy and physiology of the adult caprine (Capra hircus L.) stomach have been investigated extensively, the early development of the abomasum has not yet been fully elucidated. The glandular part of abomasum plays an important role in digestion of ingested food by action of gastric juices. Very few studies have been conducted so far regarding histogenesis of goat foetal abomasum in India. In the present study, we have investigated the embryonic and early foetal development of the goat, Capra hircus L. fundic abomasum. We collected 36 developing abomasum of healthy and normal embryos/foeti of goat and assigned them into three group viz. Gr. I (0-50 days of gestation), Gr. II (51-100 days of gestation) and Gr. III (101-150 days of gestation). Small pieces of tissues were processed by routine paraffin. The wall of glandular stomach, the fundic part, was composed of epithelium, pleuripotent blastemic tissue and serosa up to 44 days of gestation. Tunica muscularis became separable at 46 days of gestation. The epithelium was stratified type up to 50 days and gradually changed to pseudo-stratified columnar to simple columnar type from 76 days of gestation. Primary and secondary abomasal folds were observed at 51 and 76 days of gestation, respectively. Gastric pit, the fore runner of gastric gland was reported first at 70 days. The gland became branched tubular type at 145 days. The cells found in the mucosa of the abomasum were surface epithelial cells, chief cells, parietal cells, mucous neck cells and undifferentiated cells. Chief and parietal cell were observed at 76 days and mucous neck cells at 82 days of gestation. Reticular, collagen and elastic fibers came into sight at 38, 76 and 100 days of gestation, respectively. The present study is expected to supplement known data and knowledge regarding histogenesis of goat fetal abomasum and help in diagnosis and treatment of related congenital anomalies.

Varsha gupta

Intensively cultivated rice-wheat cropping system of the Indo Gangetic plain (IGP) is a potential source of greenhouse gas (GHG) emissions.Agriculture sector emits GHGs like methane (CH4) and nitrous oxide (N2O). The total amount of GHGs emitted by a product is known as its carbon footprint (CFP).Quantification of CFP of crops will help in identifying management practices to reduce CFP of crop production. Studies related to assessing of CFP of agricultural products are lacking. The present review paper was aimed to discuss about the studies done on GHG emission from rice-wheat cropping system of the Indo Gangetic plains. The paper elaborates on what is CFP, how to calculate CFP of rice-wheat cropping system with the help of different case studies. The paper provides insights about certain agricultural management practices which can help in reducing CFP of rice-wheat cropping system. Discussion from this paper signifies the importance of carbon footprint assessment in maintaining the sustainability of rice wheat cropping system.

Dr.renu dhupper

Rationale: Trisomy 18, often known as Edwards syndrome. It is a common chromosomal disorder characterized by the presence of an extra chromosome 18. Unfortunately, survival past the first year is quite rare, and there are only a few reports of individuals living long-term without needing corrective surgery. This case sheds light on an unusual situation where a patient survived for an extended period despite having severe congenital heart defects. Patient concerns: A 5-year-old girl, already diagnosed with trisomy 18, was admitted to the hospital after experiencing a cough and diarrhea that started after she began taking a nutritional powder supplement. The patient had a history of admission to neonatal intensive care for 1 month due to transient tachypnea of the newborn, mild retractions, and grunting. Additionally, she had intrauterine growth restrictions, dysmorphic features, and hypotonia. Diagnoses: Clinical examination revealed dysmorphic features, hypoxia, and a cardiac murmur. Chest radiography reveals central infiltration with cardiothoracic ratio 60%. Genetic testing confirmed the presence of trisomy 18, and an echocardiogram showed multiple congenital defects with significant right ventricular hypertrophy. Interventions: Initial management began with administering oxygen, performing metabolic tests, and a chest x-ray. However, because of ongoing low oxygen levels linked to her heart defects and pulmonary hypertension, long-term home oxygen therapy was initiated. A comprehensive supportive care with multidisciplinary team support was the main management. Outcomes: Throughout her treatment, oxygen saturation did not exceed 85%, and the patient’s development has remained severely delayed, with no significant motor or cognitive milestones. The patient had a long life expectancy for her complex heart defects, but eventually died of cardiac arrest. Lessons: This case shows the possibility of prolonged survival in trisomy 18, even with severe congenital heart defects, emphasizing the importance of multidisciplinary management and family-centered counseling. Documenting such cases expands understanding of this syndrome and guides long-term care strategies.

Mohamad banat

Brushites are the most commonly found phosphate stones in the kidneys, ureters and urinary bladder. The study was conducted to observe the possible growth patterns of brushite crystals in the gel for 14 days. The crystal formation was observed as a bullet, needle, platy, columnar shaped and their aggregates. Magono and Lee's meteorological classification further explained these shapes. Besides the morphology, the average size, number and weight of crystals were also observed on the 7th and 14th days. Energy Dispersive X-ray, Fourier Transform Infra Red spectroscopy and Scanning Electron Microscopy were used to characterize the crystals. These results can help to determine the promotion, modulation and inhibition of the crystals, which will be helpful in evaluating the risk factors and prophylactic management of brushite-type urinary stones.

Dr. salman ahmed

This study aims to determine the effect of communication, competence and work discipline on job satisfaction at PT. Tribahtera Srikandi. This research was conducted at PT. Tribahtera Srikandi lasted for 6 months, starting from January 2020 to June 2020. Sampling was taken in research using proportional random sampling method. The population in this study are all employees of factory workers in PT. Tribahtera Srikandi 155 people. The number of respondents in this study was established by using the statistics of the population, amounting to 112 people. The instruments used to collect data are questionnaires from communication, competence, work discipline and job satisfaction. The data analysis tool in this study is a multiple linear regression by carrying out a classic assumption test that is continued by testing the partial hypothesis or t test, the simultaneous hypothesis test or the F test, and the calculation of the coefficient of determination. The contribution of communication, competence and work discipline variables explained the variable of job satisfaction as big as 0.765 or 76.5%. The remaining 0.235 or 23.5% was influenced by other independent variables not examined in this study.

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The purpose of this study is to explore the belief of teacher educators about the relationship between teaching and research. Keeping in view the role of the teacher educators, a survey was done. The beliefs of teacher educators were explored with the help of an opinionaire. The collected data were analyzed through qualitative method of analysis. It was found that the secondary teacher educators were positive about the need of research with a little dilemma between teaching and research.

Rupal mankad

The Construction Industry is one of the industries contributing highest GDP in Indian economy. The material that is most chosen in construction Industry is concrete. Concrete is a material made with Cement, Fine aggregate in the form of sand, Coarse aggregate in the form of gravel and water. With increasing scarcity of sand, construction works are coming to jolt and thereby increasing the need for choosing an alternative material. Vermiculite is a material which after exfoliation can be used as a filler material replacing sand partially without affecting strength much. One more material Granite (by product which is a waste is causing lot of environmental Issues), produced from granite industry, is available in India in several million tons. Coarse aggregate generally used is a crushed aggregate obtained from rocks like granite, basalt and soon. Recycled aggregate is an aggregate which is obtained after demolishing of an existing building, which is a waste causing economical in balance and which if put into use can not only decrease the construction cost but also make this waste into a better use. In the present study, for a M35 grade of concrete, Vermiculite (0, 5%, 10% and 15% of weight of sand) and granite powder (fixed at 10% of weight of sand used) is used to replace sand partially and in the place of normal coarse aggregate, recycled aggregate is used which is 20 mm passing and 12 mm retained After preparation of Mix-Design(1:1.83:2.69 with w/c ratio of 0.38) the concrete cubes are casted to test for compressive strength after curing for 28 days, 56 days and 90 days. Forsec brand super plasticizer is used to take care of workability requirements. Durability test in the form of resistance to attack of sulphuric acid was conducted along with compressive strength. The test results were promising at 10% replacement levels of Vermiculite.

Kiran kumar narasimhan

Pada awal terjadinya pandemi COVID 19, telah terjadi banyak hal yang mengakibatkan perubahan di tengah masyarakat. Salah satunya adalah di kegiatan belajar mengajar. Berangkat dari hal tersebut maka pada pertengahan Agustus 2020 dimulailah satu kegiatan untuk membantu para guru yang ada di daerah untuk bisa beradaptasi dengan perubahan terkait kegiatan belajar mengajar pada masa pandemi. Kegiatan ini dilaksanakan dalam beberapa bulan dengan dua kegiatan utama dilaksanakan secara daring dan kegiatan pendampingan juga secara daring. Pada April 2021 didapatkanlah hasil dari kegiatan ini yang sebagian besar menilai kegiatan positif dan membantu dalam aplikasi kegiatan belajar mengajar. Hanya saja yang disayangkan kegiatan ini tidak menjangkau banyak peserta.

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The use of geo-morphometric variables to discriminate fish populations is one of the appropriate, effective and widely adopted approaches to study population dynamics. To determine intrinsic population variability in goldstripe ponyfish, Karalla daura sampled from Keti Bunder, Karachi Fish Harbour, Hawks Bay and Pasni along the coastal belt of Pakistan. Size frequency distribution based on normal distribution demonstrates that individuals of 13 cm total length were common in all groups. Some fifteen morphometric and six geometric variables were used to develop Principal Component Analysis (PCA) that revealed (76%, 13.9% and 9.8%) variation deduced from first three components. The population sampled from Karachi fish harbors showed significant taxonomic variability. An eigenvalue 7.251 and canonical correlation 0.937 among four groups was appraised from PCI whereas Wilks’ Lambda test of function λ = 0.27 was significant at P <0.05. The highest variance percentage was the most correlated among the groups defined by total length, girth, 2nd dorsal fin, pectoral fin rays, eye dia, snout to extended gill cover and head length parameters. PC-II accounted for 13.9% of the variance that are more correlated with standard length, snout to eye tip, eye tip to first dorsal fin, base of 1st dorsal fin, last fin ray to tip of caudal, anal fin ray to pelvic fin ray, chin to snout and pelvic fin to pectoral fin. PC-III showed 9.8% variance with fork length, total weight, anal fin rays, last anal fin ray to 1st dorsal fin, tip of caudal fin to last anal fin ray, last anal fin ray to 1st anal fin, first pelvic fin to chin, eye to chin, 1st dorsal fin to last anal fin ray and last dorsal ray to last anal fin ray. among the groups. Whereas PC-IV has 0.3 % variance denoted by total weight, tip caudal fin to last anal fin ray. The PCA displayed a clear discrimination by sampling site, especially specimen from Karachi fish harbor were distinct from other location. Keti Bandar specimen was not dispersing as much as by geographical discrimination. Overall, results revealed that different topographies and environmental conditions causing significant variation in populations of Karalla daura. Therefore, it is assumed that this species has ability to adopt different ecosystem for survival despite acquiring adverse impact on phenotypic characteristics.

Imtiaz kashani

Stem cells hold great promise for tissue regeneration and have the potential to treat many incurable degenerative diseases. Cancer stem cells (CSCs), or cancer initiating cells, have the ability to self-renew and differentiate into heterogeneous lineages of cancer cells. Current stem cell therapies face limitations, such as limited stem cell sources, time consumption, tumor formation, and immune rejection upon allogeneic transplantation. Allogeneic stem cell treatments simplify stem cell manufacturing and reduce transplant time, but their therapeutic potential is limited by human leukocyte antigen (HLA)-matched donors. CSCs retain characteristics essential for tissue regeneration. However, several limitations hinder cancer stem cell reprogramming with pluripotent factors. The development of 3D culture models for tissue imitating extracellular matrix in cancer cell lines aims to enhance CSC enrichment. This mini-review focuses on a new strategy for treating incurable degenerative diseases involving in vitro and in vivo 3D cancer models and the induced differentiation of CSCs into mature normal cell types. This allows tissue survival without immune rejection and offers a safe alternative to cancer stem cell reprogramming with pluripotent factors. In conclusion, preservation and banking of allogeneic CSCs offer an alternative, readily available, and safe strategy that can be used to facilitate stem cell-based cell therapy.

Josita alloysius

The 2019 coronavirus (COVID-19) pandemic is spreading worldwide, with a spectacular increase in death missing any effective therapeutic treatment up to now. Molecular docking is a recognized computational tool to assist in early drug discovery and development. Molecular docking analysis was carried out using 2-(4-(aminomethyl)phenyl)isoindoline-1,3-dione Schiff base conjugates with SARS-CoV-2 protease enzyme and COVID-19 main protease in apo form 6M03). The compounds with the best normalized docking scores to protease enzyme (6LU7) were ARG3 (-8.1 kcal/mole), ARG7 (-8.1 kcal/mole) and ARG6 (-8.0 kcal/mole). The best docking ligands for main protease in apo form (6M03) were ARG7 (-8.7 kcal/mole), ARG6 (-8.6 kcal/mole) and ARG3 (-8.4 kcal/mole). The structural similarity between these conjugates inspired us to perform in silico studies to check their possible binding interactions with essential SARS-CoV-2 proteins. These studies provide insight into the potential binding between Schiff base derivatives and SARS-CoV-2 proteins to provide an insight for finding an effective therapy. Finally, ADMET calculations were performed for the Schiff base compounds to predict their pharmacokinetic profiles.

Mediterranean journal of pharmacy and pharmaceutical sciences

Malignant melanoma is the most dangerous type of skin cancer. It is becoming more common globally and is increasingly resistant to treatment options. Despite extensive research into its pathophysiology, there are still no proven cures for metastatic melanoma. Unfortunately, current treatments are frequently ineffective, costly, and have several adverse effects. Natural substances have been extensively researched for their anti-MM capabilities. Chemoprevention and adjuvant therapy with natural products is an emerging strategy to prevent, cure or treat melanoma. Numerous prospective drugs are found in aquatic species, providing a plentiful supply of lead cytotoxic chemicals for cancer treatment. Anticancer peptides are less harmful to healthy cells and cure cancer through several methods, such as altered cell viability, apoptosis, angiogenesis/metastasis suppression, microtubule balance disturbances and targeting lipid composition of the cancer cell membrane. This review addresses marine peptides as effective and safe treatments for MM and details their molecular mechanisms of action.

Dr. salman ahmed

The COVID-19 crisis has impacted all dimensions of our lives say it as the public health, the labour system, the social interaction, the political debate, the use of public spaces, the economy, the environment, and last but not the least it has proved to be a major contributor to the cultural value system of the individual living in society. This research paper is to analyse and understand the changes enforced by this pandemic on Indian culture and individual of the society. It also analyses the context of COVID-19 scenario with special reference to Indian culture and Hofstede’s theory of cultural dimension. This research paper is an attempt to emphasize the changes in culture and value system during the COVID-19 pandemic faced by India. India is enriched enough in cultural dimensions to combat COVID-19. The Hofstede’s model analysed in depth also leads to this finding that it also fits well in the present context. Thus, it is hereby summed up that as India is enriched in its cultural values it has posed itself as a fighter for this pandemic

Mamta gaur

Lightweight materials are increasingly being used in engineering applications today. Composites are replacing traditional metallic materials in a variety of sectors, including aerospace, defence, and aircraft production, where there is a demand for structural materials with high strength-to-weight and stiffness-to-weight ratios. Natural fibre composites are also increasingly used in place of synthetic fibre composites in a variety of technical fields due to their affordability and environmental friendliness. In this particular study, Kevlar (Aramid fibres) is combined with other materials to improve the mechanical characteristics and impact resistance of composites. The only material that costs more than Kevlar is carbon fibres. The goal is to maximize mechanical qualities while utilizing the fewest amounts of pricey Kevlar fibres possible. The hand layup technique was used to create the hybrid composites, which included both natural and Aramid fibres. The performance of various mechanical properties was then assessed. In addition, a morphological examination was done to look at the interior structure of the composite materials that were examined. The results show that the hybrid composite, with or without the addition of nanoparticles, demonstrates great strength with little reliance on Kevlar fibres.

Boopathy govindarajan

A P2P network can be an ad hoc connection- a couple of computers connected via a Universal Serial Bus to transfer files. And these networks are vulnerable to peers. The traditional security techniques are insufficient for P2P networks as they are insecure by their very nature. There’s no centralized server controlling access to shared resources in a P2P network which have unique challenges including identity management of the peers, secure reputation data management, Sybil attacks, and above all, availability of reputation data. The future actions are predicted where peers are encapsulated in its digital reputation, based on the past behaviour of the peer.Thus a peer’s reputation allows it to cooperate and prevent from malicious activities. The cryptographic protocol is coupled with selfcertification and cryptographic mechanisms for identity management and countering Sybil attack.

Dr h shaheen

Vigna radiata (L.) R. Wilczek, commonly known as Mung bean, is one of the most important pulse crops grown from tropical to sub-tropical areas worldwide. Mung bean is reported to help prevent the loss of nails and hair, reduce the risk of hypercholesterolemia and coronary heart disease, and decrease the absorption of toxic substances. Flavonoids and phenols are reported from this plant. Antioxidant, anti-diabetic and hypocholesterolemic activities are also shown by Vigna radiata

Dr. salman ahmed

The study aims to explore the possible morphological features of calcium hydrogen phosphate dihydrate (brushite) crystals on a glass slide. The study was conducted on a glass slide under a microscope to observe the growth patterns. As a result, needle, platy, star shape, and tetragonal bipyramidal crystals were observed. Different patterns of platy crystals, like plates with spatial branches and radiating assemblages of platy crystals, were also found.

Dr. salman ahmed

This study was carried out to evaluate the effects of thermal processing techniques on the nutrient and antinutrient contents of pigeon pea (Cajanus cajan) flours. The pigeon pea seeds were sorted, cleaned and divided into five equal lots of 0.5kg each. Four lots of pigeon pea seeds were processed into blanched, boiled, roasted, and autoclaved pigeon pea flours, while the fifth lot was processed raw and used as control. The raw and thermally processed samples obtained were analysed for nutrient and antinutrient composition using standard methods. The proximate composition of the samples showed that the flours had a range of 8.61 - 11.46 % moisture, 21.13 - 23.94 % crude protein, 1.26 - 1.68 % fat, 5.12 – 6.10 % crude fibre, 1.74 – 2.97 % ash, 55.56 – 60.41 % carbohydrate and 333.45 - 342.75 kJ/100g energy, respectively. The mineral composition showed that the flours contained 86.24 – 144.72 mg/100g calcium, 137.80 – 170.33 mg/100g magnesium, 125.86 - 156.76 mg/100g potassium, 66.66 – 95.62 mg/100g sodium, 4.38 – 6.64 mg/100g iron and 130.27 – 178.29 mg/100g phosphorus, respectively. The vitamin content of the flours were 3.09 - 4.33 mg/100g ascorbic acid, 0.05 - 0.17 mg/100g thiamine, 0.03 - 0.21 mg/100g riboflavin, 0.13 - 0.28 mg/100g niacin, 3.21 - 6.25 mg/100g vitamin A and 1.10 - 2.70 mg/100g vitamin E, respectively. The antinutrient composition of the flours also showed that the levels of trypsin inhibitor, tannin, phytate, oxalate, saponin and haemagglutinin ranged from, 2.30 – 5.61 Tiu/mg, 0.81 – 1.5mg/100g, 1.12 - 4.18mg/100g, 0.48-4.01 mg/100g, 1.28 – 3.66 mg/100g and 1.30 – 7.44 Hiu/g, respectively. Therefore, the study showed that thermally processed pigeon pea flours could be used as nutrient dense ingredients in the preparation of a wide range of foods for children, adolescents and aged adults especially in developing countries where the problems of protein-energy malnutrition and micronutrients deficiencies are prevalent than the raw sample.

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