Blind Taste Test of Soft-drinks – A Comparison Study on Coke and PBrand equity is “The differential effect that brand knowledge has on consumer response to the marketing of that brand” (Keller-1993).Brand equity is the added value a product acquires as a result of past investments in the marketing activity for the brand.This marketing activity resides in the mind of customers and as a result customer shapes a perception about the brand, biggest challenge here is creating positive perceptions by ensuring that customers have right type of experiences with product so that both functional experiences as well as emotional experiences become associated with the product.Thus Brand perception is the imagewhich a brand creates in the mind of the customers due to the various associations linked with the brand. The simplest way tounderstand what brand equity is to understand the typical results of product sampling and comparison tests. One such test is blind taste test in which consumers sample a product without knowing the brand what they consume and consuming the same product knowing brand i.e., open test. When consumers report different opinions about branded and unbranded versions of identical products, it must be the case that knowledge about the brand has changed their perceptions. Thus, consumers’ perceptions of product performance are highly dependent on their impressions of the brand that goes along with it Pepsi
Patent foramen ovale (PFO) is a prevalent congenital cardiac anomaly. It is increasingly acknowledged as a significant factor in cryptogenic ischemic stroke, especially among young adults experiencing otherwise unexplained cerebrovascular incidents. This review summarizes recent advances in the epidemiology, pathophysiology, diagnostic strategies, and management of PFO-related stroke. The article examines the intricate mechanisms of PFO-associated strokes, including paradoxical embolism, in situ thrombus formation, and atrial cardiopathy, while emphasizing the significance of anatomical risk factors like large shunt size and atrial septal aneurysm. The clinical implications of PFO in various disorders, such as migraine with aura, decompression sickness, and high-altitude pulmonary edema, are also analyzed. Diagnostic modalities such as echocardiography and transcranial Doppler are compared, focusing on their sensitivities and procedural details. The review focuses on evidence-based methods for medical, interventional, and device-based closure of PFO, highlighting patient selection and ongoing controversies. The ongoing uncertainties surrounding causal relationships, risk stratification, and optimal therapy highlight the necessity for continued research. This review offers a current synthesis for clinicians and researchers addressing the challenges associated with the evaluation and management of PFO in stroke prevention. To achieve the aims of the article and make it concise, PubMed, Google, EMBASE, Google Scholar, and Scopus were searched for original and review articles published in the last 10 years. Several keywords, phrases, and texts were utilized.
Arisaema jacquemontii Blume (Araceae) is a medicinally important plant for treating different diseases, especially dermatological disorders. Alkaloids, phenols, terpenes, flavonoids, glycosides, and tannins have been reported from this plant. Antioxidant, antifungal, antibacterial and anticancer activities are also shown by Arisaema jacquemontii. The present review attempts to compile all the previous data based on its medicinal uses, phytochemistry and pharmacology reported in the earlier articles.
A zoonotic disease is an infectious disease caused by pathogens such as bacteria, virus, rickettsia, fungi, parasite or prion that has been transmitted from an animal, especially a vertebrate to human beings. Usually, the first infected human transmits the infectious agent to other humans very rapidly; it is one of the important concerns of zoonoses. The World Health Organization (WHO) currently list the Emerging infectious diseases (EID) of epidemic issues in their research and development blueprint as COVID-19 (Corona viruses), Middle East Respiratory Syndrome (MERS), Severe Acute Respiratory Syndrome (SARS), Ebola and Marburg viruses (Filovirus), Crimean Congo haemorrhagic fever (Nairo virus), Lassa Fever (Lassa virus), Nipah (Henipa virus ), Rift Valley fever (Phlebo virus) and Zika (Flavi virus). Due to the deadly pandemics facing by the globe, it is essential to understand the way of transmission of emerging viruses, its mode of infection and important measures to eliminate or control them from the world is essential. However, mankind overcomes so many deadly viruses with the help of scientific knowledge, through vaccination, new therapies, drugs etc. Nowadays, viral zoonoses like rabies (Lyssa virus) are 100% preventable through vaccination and medication even though, humans face lots of new threats especially emerging zoonosis diseases like Covid19. This review summarized the major zoonotic viruses affecting human beings, their source, pathogenicity and its important ways to overcome the transmission of microbes from animal to humankind.
Congenital constriction band syndrome (CBS) is a rare condition characterized by either partial or complete circular constrictions around limbs or digits. Possible consequences include acrosyndactyly of the digits, terminal amputations, and localized swelling with digital edema distal to the constrictions. Occasionally, a constriction band may lead to injury of a peripheral nerve. We report a case of CBS in a newborn presenting with radial nerve palsy caused by a constriction band at the level of the arm. Surgical release of the congenital constriction band was performed at 1 month of age, including neurolysis of the radial nerve. As a result, the nerve was decompressed, and hand function was restored. Given the rarity of radial nerve palsy as a complication of congenital constriction bands, this case enriches the limited literature by emphasizing the importance of early diagnosis and prompt surgical intervention to optimize functional outcomes. It also highlights the need for increased clinical vigilance and provides practical insights into managing isolated radial nerve palsies.
This study was carried out to verify all the manual process involved in generating Students Examination Result and to seek a way of automating the system for effective operations. Computer and its appreciations have become vital tools in the economic, industrial and social development of advanced countries of the world. Most educational institutions in Nigeria, such as Universities, Polytechnics and Colleges of Education still operate on the manual method of record keeping and computation of students’ grade point averages (GPA) which is time-consuming and error-prone especially when the number of students is large. This paper examines the inadequacies involved in the manual method of calculating Students CGPA (cumulative grade point average) and proposes a solution by developing a software application to facilitate the automated processing of the results. The software was developed using the Microsoft Excel spreadsheet program. The developed software was tested and found to performed well and produced expected results on completion. With it, it was possible to compute Grade Point Average (GPA) and Cumulative Grade Point Average (CGPA) for each student based on examination scores entered. The new system has some qualities such as reduction in the cost of processing of information, reduction in time spent in computing GPA and generating transcripts, increase in accuracy and efficiency, and elimination of duplication of effort which makes it superior to the manual system of student record keeping. This new system is flexible and can be modified to suit any kind of student’s record-keeping and data processing.
This research will discuss the new destination of Toraja coffee as a tourism development strategy. Questions that will be answered is what is the attraction of Toraja coffee tourism as a new tourist destination. Methods of research conducted are field observation and interviews with coffee stakeholders as an informant and foreign tourists as respondents. The results of this study concluded that the appeal of Toraja coffee as a tourism destination is Toraja coffee has characteristic (taste) differently based on the planting area Toraja coffee. There are 15 names of coffee products based on the region and the name of Toraja coffee products taken from the region. E.g. coffee Toraja Sapan, derived from the Sapan area, and coffee Sesean derived from the village of Sesean. Perception of foreign tourists to Toraja coffee is that the taste of Toraja coffee is different based on the height of the coffee planting area to be a tourism identity Toraja Agritourism.
Rice bean (Vigna Umbellata), a traditional crop cultivated across South, Southeast, and East Asia, is characterized by its wild variety spanning the tropical monsoon forest climatic zone. Despite its vast nutritional and production potential, falling within the leguminous family Fabaceae, the rice bean represents one of many underutilized crops. Indigenous to South and Southeast Asian regions, particularly hilly areas, rice bean is cultivated alongside crops like maize, forming an integral part of impoverished farming communities' livelihoods. Despite its extensive utilization in traditional practices, its commercial significance remains largely unrecognized. However, recent attention has been drawn to the rice bean's nutritional richness, bioactive compounds, and various medicinal properties, including anti-inflammatory, antioxidant, and antidiabetic effects. This significant attention underscores its potential for commercialization and contribution to improving the livelihoods of underprivileged populations. Furthermore, its cultivation and processing give rise to diverse products, reflecting its cultural significance and adaptability across different regions.
In this article, we establish the exact wave solutions of the Boussinesq equation and the (2 + 1)-dimensional extended shallow water wave equation by applying the new generalized (G'/G)-expansion method. When the condition of the fluid is such that the horizontal length scale is much greater than the vertical length scale, the shallow water equations are mostly suitable. In Ocean engineering, Boussinesq-type equations are commonly used in computer simulations for the model of water waves in shallow seas and harbors. We explained the new generalized (G'/G)-expansion method to seek further general traveling wave solutions of the above mentioned equations. The traveling wave solutions attained by this method are exposed in terms of hyperbolic, trigonometric and rational functions. The shape of the obtained solutions are bell shaped soliton, kink soliton, singular kink soliton, singular soliton, singular periodic solution and compaction. This method is very influential mathematical tool for extracting exact solutions of NLEEs which frequently arise in mathematical physics, engineering sciences and many scientific real world application fields.
Hypertension is a high-risk factor for cardiovascular diseases and its prevalence rate is increasing due to risk factors such as unhealthy lifestyles and aging populations. Managing hypertension is crucial to avoid complications such as stroke, heart failure, and kidney failure. In Northern Cyprus, where hypertension is a growing public health concern, pharmacists are increasingly recognized as key players in managing this ongoing condition. This study investigates the impact of pharmacists in controlling hypertension in Northern Cyprus through a survey-based observational approach. Data were collected from 70 hypertension patients engaging with community pharmacists. The results highlight pharmacists’ contributions to patient education, blood pressure monitoring, and medication adherence. Relevant studies in other countries contextualize the findings about the importance of the pharmacist role. An analysis of the data confirms significant improvements in patient outcomes with pharmacist interventions. The survey results provide insights suggesting that overcoming systemic barriers and strengthening collaboration can optimize pharmacists' roles in managing hypertension in Northern Cyprus.
Mediterranean journal of pharmacy and pharmaceutical sciences
Social bots are computer programs created for automating general human activities like the generation of messages. The rise of bots in social network platforms has led to malicious activities such as content pollution like spammers or malware dissemination of misinformation. Most of the researchers focused on detecting bot accounts in social media platforms to avoid the damages done to the opinions of users. In this work, n-gram based approach is proposed for a bot or human detection. The content-based features of character n-grams and word n-grams are used. The character and word n-grams are successfully proved in various authorship analysis tasks to improve accuracy. A huge number of n-grams is identified after applying different pre-processing techniques. The high dimensionality of features is reduced by using a feature selection technique of the Relevant Discrimination Criterion. The text is represented as vectors by using a reduced set of features. Different term weight measures are used in the experiment to compute the weight of n-grams features in the document vector representation. Two classification algorithms, Support Vector Machine, and Random Forest are used to train the model using document vectors. The proposed approach was applied to the dataset provided in PAN 2019 competition bot detection task. The Random Forest classifier obtained the best accuracy of 0.9456 for bot/human detection.
This document will discuss some crucial operational aspect to the National Agricultural Development Company (NADEC) https://nadec.com.sa/ dairy Milk production company such as how well the inventories within the production system are currently managed, detailed illustration of the critical operations involved within NADEC production system presenting a logical operational flow, identify the two points where the organisation’s delivery system may fail to align its operational performance measures, how a lean approach could be utilised in the production system to reduce the failings potentially and the three key findings discussing the extent to which the lean approach may assist the production system with aligning its operational performance measures
The aim of this study was to evaluate the proximate and micronutrient composition, physical, biochemical and sensory properties of the bread produced from blends of wheat, acha, uzaaku and unere composite flours. Six samples (A-F) were produced in the following ratios A= 100:0:0 (100% Wheat), B= 80% wheat flour, 10% acha, 5% uzaaku flour, 5% unere; C = 70% wheat flour, 10% acha, 10% uzaaku flour, 10% unere; D = 60% wheat flour, 15% acha, 15% uzaaku flour, 10% unere; E = 50% wheat flour, 20% acha, 15% uzaaku flour, 15% unere; F = 40% wheat flour, 20% acha, 20% uzaaku flour, 20% unere. The parameters were analyzed using standard methods. The proximate composition of the bread showed significant increase (p<0.05) in protein, fat, crude fibre, ash, and caloric (energy) value which ranged between 7.69-18.32%, 2.41-3.70%, 2.473.86%, 3.09-4.03%, and 285.25-304.06 (Kcal/kg) and a significant decrease (p<0.05) in moisture content (20.72-26.14%) and carbohydrate (49.37-58.20%), respectively. The micronutrient content showed increase in calcium, magnesium, potassium, iron, zinc, phosphorus, vitamin B1, B2, B3, A and C as the amount of substituted flour blends increases. The result of the physical properties showed decrease in the loaf weight, loaf height, loaf volume and specific volume ranged from 240.60-218.80 g, 3.33-6.66 cm, 155.00-205.00 cm3, 0.71-0.85 cm3/g, respectively. The result of the serum biochemical parameters of rats fed the composite bread samples showed significant decrease (p<0.05) in AST, ALT, ALP, Bilirubin, creatine, urea and albumin values, respectively. The sensory attributes of the bread showed significant differences (p<0.05) in colour, aroma, taste, crumb texture and general acceptability such that the values obtained ranged from 6.05-8.90, 6.008.45, 6.40-8.60, 5.85-8.30 and 6.10-8.35, respectively. The findings of the study showed that supplementation of wheat with 10% acha, 10% uzaaku and 10% unere flour blends could produce well accepted bread samples.
The Training and Development is considered as most important task to reach organizational goals. HR Analytics in Training of employees helps to understand better what is required among their Employees to increase Motivation and Skills which ultimately improves the employee Performance. HR Analytics is a method used to measure and organize information related to employee that give clean insights about the requirement of an employee. It also helps the Organisations to maintain record and analyse information of specific employee with specific skill sets, this helps in motivating, gaining efficiency and improving talent quality. For every organization, their employees are very precious asset. Thus, it is extremely essential to analyse, assess, and predict employee requirements. In this competitive world where new innovations come as a hurdle, it is very important to implement the new technology in organisation. This paper highlights the importance of providing training to the employees in organisation and its influence on employee’s better performance, organisational achievement and employees satisfaction.
For banking employees around the globe, stress on the job can be a challenge; stress can be sometimes positive and sometimes negative. Positive stress leads to productivity and negative stress leads to loss for the organization. There is already a certain level of stress in Banking employees work life and then encounter even more stress arising from the work pressure that Banking employees face on the job. Many employees cannot cope with such rapid changes taking place in the jobs. Role conflict, Service for customer, contribution, rapid technological change, lack of customer response is the great transaction of stress for the banking workers. The aim of this research is to understand roots and outcomes of job stress on the employee performance in banking sector.
Comparative analysis of plant diversity with reference to Chamundi hills, in Mysore District of Karnataka State
Hemophagocytic lymphohistiocytosis (HLH) is a distinct medical condition characterized by symptoms such as fever, hepatosplenomegaly, cytopenia, hypertriglyceridemia, hypofibrinogenemia, and the presence of hemophagocytosis in the bone marrow and other organs. HLH can be classified as either hereditary or secondary, linked to various infections, autoimmune disorders, or cancers. The occurrence of malaria-associated HLH in newborns is considered rare. This report details a case involving a newborn diagnosed with mixed-type malaria complicated by HLH. The diagnosis was delayed because of the rare occurrence of malaria infections in Libya, which the treating clinicians did not initially take into account. The patient received supportive care and antimalarial treatment, which yielded excellent results, and was subsequently discharged from the hospital.
In some countries, a high percentage of the population relies on traditional plants for treating certain diseases. The aim of this study was to investigate the effect of G. alypum extract (GAE) and Alhagj marorum extract (AME) on lipid profiles in experimentally induced hypercholesteremic rats and on the blood pressure of experimentally induced hypertensive rats. Male Wistar rats weighing 200 - 300 g were divided into five groups: group 1 received a normal diet (negative control), group 2 received a high lipid diet containing coconut oil (10 g/kg/day), cholesterol (4 g/kg/day) and cholic acid (0.20 g/kg/day) (positive control), group 3 received a high lipid diet together with clofibrate (50 mg/kg/day), group 4 received a high lipid diet together with AME (200 mg/kg/day) and group 5 received GAE (200 mg/kg/day). The experiment continued for two weeks, then the rats were sacrificed and blood samples were collected for estimation of cholesterol, triglycerides, high-density lipoprotein and low-density lipoprotein. To induce hypertension, rats were divided into two groups (n = 8 in each group). Group 1 received normal saline (control) and Group 2 received dexamethasone (0.40 mg/kg, i.p.) for seven consecutive days. Later, the rats were anesthetized using thiopental and the carotid artery was cannulated for recording blood pressure. AME (40 mg/kg) or GAE (40 mg/kg) were injected through a cannula placed into the internal jugular vein at a dose volume of 0.1 ml. Systolic and diastolic blood pressure were measured before and after plant extract administration. The results showed that clofibrate GAE extract and ANE extract significantly decreased cholesterol, triglycerides, low-density lipoprotein and high-density lipoprotein as compared to high-lipid diet-treated rats. Data also indicated that administration of GAE or AME extract significantly decreased systolic and diastolic blood pressure in experimentally induced hypertensive rats. In conclusion, GAE and AME have antihyperlipidemic and antihypertensive activities and further investigation is needed to clarify the mechanism of these effects.
Mediterranean journal of pharmacy and pharmaceutical sciences
Cryopreservation is a process that preserves intact living cells, tissues or any other biological constructs by cooling and storing the samples to very low temperatures in order to maintain their viability and to save them for future use. At very low temperatures, enzymatic and chemical activities that may cause harm to the biological material are effectively stopped. Cryopreservation methods look to reach very low temperatures without causing further harm caused by the creation of ice crystals during freezing. Cryopreservation human samples for storage including variety of diseases such as cancer, genetic and degenerative disorders and bio-banking. This review aims to describe and highlight dimethyl sulfoxide in cryopreservation. Dimethyl sulfoxide is a non-toxic solvent and is one of the most commonly used pharmaceutical agent with a varied range of pharmacological actions including membrane penetration, anti-inflammatory effects and local analgesia as well as weak bacteriostatic. The main use of dimethyl sulfoxide is a vehicle for some drugs to enhancing the action of the drug and helping penetration of other drugs into the skin. However, dimethyl sulfoxide has been the cryopreservative agent of choice in situation to its exceptional performance in mitigating freezing-related damages. It is frequently used in cell banking applications as a cryoprotectant. When added to media, it prevents intracellular and extracellular crystals from forming in cells during the freezing process. There has been a concern over the toxicity of dimethyl sulfoxide and its potential side effects in different highly concentration after administration to patients. Therefore, there has been growing demand for robust dimethyl sulfoxide for cryopreservation method that can improve safety and maintain potency and efficacy
Mediterranean journal of pharmacy and pharmaceutical sciences
Worldwide, the threat created by antibiotic resistance to public health calls for immediate action. Antibiotic resistance is one of the main causes of the emergence and spread of dispensing of antibiotics without a prescription. This study aims to investigate the dispensing of antibiotics without a prescription and the reason behind that in the community pharmacy in Libya. The study was randomized analytical conducted between March and April 2023 among pharmacists and assistant pharmacists employed by community pharmacies in various Libyan areas Tripoli, Zawia, and Sabratha. The data were analyzed by Fisher's exact and Chi-square tests to predict the determinations of dispensing antibiotics without prescriptions. In this study, a total of 293 participants were included, 63 had been excluded because they did not meet the inclusion of the study. The remaining 230 were enrolled for final analysis, most of them were female subjects (70.7%). Findings showed that 78.7% of the participants consulted with patients about the reason for requesting a specific type of antibiotic, while 68.7% dispensed antibiotics with probiotics. Study participants with 2 - 4 years' work experience were 76.6% higher toward dispensing of antibiotics without a prescription (P=0.683). The major reason for dispensing antibiotics without prescriptions were pharmacists knowledgeable enough to give a patient antibiotics without a prescription (68.3%). In Libya, misuse of antibiotics by the public is widespread. People can purchase antibiotics without prescription. Thus, dispensing of antibiotics without a prescription in community pharmacies is an alarming issue in Libya which can increase antibiotics resistance. Pharmacists' knowledgeable is high in dispensing patients antibiotics without a prescription, but patient pressure and financial issues are the major reasons behind dispensing antibiotics without a prescription. It can be recommended that the importance of antimicrobial stewardship and the need for ongoing education support for community pharmacy professionals is of importance.
Mediterranean journal of pharmacy and pharmaceutical sciences