Forecasting methods from averaging regression analysis lines, reversed and direct lines. With both lines intercepting laid the turning points in direction of original line. The average regression method.

Dr abdul rahim wong

The strategy is a means of establishing the organisation's purpose in terms of priorities for resource allocation, action programs and long term objectives (Grant 2005). Chandler (1962) defines strategy as determining the primary long-term goals of an organisation, the adoption of courses of action, and the allocation of necessary resources. Besides, the strategy also focuses on allocating resources in relation to the organisation and its environment (Schendel & Hatten 1972). The strategy also pertains to the top management's decisions pertaining to its scope and the future direction. Such strategy covers an action plan on the organisation's future, commitments to specific products, services, and the markets.

Zamzam abdelazim

Technology and Isolation in the Information Period explores the social, political, and legal implications of the group and use of personal information in computer databases. In the Information Period, our lives are documented in digital case books maintained by hundreds (perhaps thousands) of businesses and government agencies. These case books are composed of bits of our personal information, which when assembled together begin to paint a portrait of our personalities. Technology has changed our working practices and now allows us to be connected 24/7. We have the power to Skype clients around the world and email or Tweet work colleagues at weekends, but is there a danger that having connectivity so readily available hinders our efforts to gain a better work/life balance? We often read articles about the correct way to manage technology and how to achieve a happy balance of relaxing away from work and being ‘Always On’ and ‘Always available’. For instance, many people choose a job that allows them to detach from the workplace on evenings and weekends, yet technology makes it difficult for others to switch off. Now, we are huge believers in the ability to use the internet, email, Facebook, Twitter, texting and to pick up the phone and talk to people, but because of technology more people are becoming distracted and losing focus. They can’t escape from the workplace and feel that the office follows them around via their Smartphone which demands attention 24/7. It wasn’t so long ago that when we took a holiday, we would plan ahead, make sure everything was order, inform clients of our absence and brief our teams so we could disappear off to distant shores and happily sit in the sun for a relaxing fortnight, avoiding drinking the local water, eating strange local delicacies and fending of mosquitoes. But I digress … Having technology at hand means that we still have an element of control at our workplace and the ability to deal with issues if they occur. The downside to this is managing that work/life balance again. On one hand the internet is a lifeline, but it can also become a ball and chain if we don’t take the time to unplug from it. Technology allows us to be in two places at once, but when employees struggle to find the right balance between their work and personal lives there is a chance that stress levels can increase leading to a potential loss of productivity and happiness in general. In a recent survey 70% of workers said that technology brings the stress of work into their personal lives. Many Researchers have recommended drawing a line between work communications and home. This not only benefits your well being, but benefits your employer too, as you will be coming back to work refreshed and recharged.

Sunita singh

The identification of isomorphism in epicyclic gear trains has been found a lot of attention by researchers for the last few years. Various methods have been suggested by different authors for the detection of isomorphism in planer kinematic chains and epicyclic gear trains (EGTs), but everyone has found some difficulties to address new issues. In this paper, a modified path matrix approach was presented in order to compare all the distinct geared kinematic mechanisms. A new method based on the matrix approach and corresponding train values is required to identify isomorphism among epicyclic gear trains and their mechanisms. The proposed method was examined on the basis of various examples from four-link, five-link, six links, and eight-link one-degree-of-freedom EGTs and six links two-degree-of-freedom EGTs. All the examples have been found satisfactory results with existing literature.

Jiyaul mustafa

Artificial Intelligence (AI) has emerged as a transformative force in the healthcare domain, revolutionizing various aspects of medical research, diagnostics, treatment, and patient care. This paper provides an overview of recent developments and applications of AI in healthcare, highlighting its potential to enhance efficiency, accuracy, and accessibility in medical practices. The integration of machine learning algorithms, natural language processing, and computer vision techniques has enabled AI systems to analyze vast amounts of medical data, support clinical decision-making, and personalize treatment plans. Additionally, AI-powered technologies play a crucial role in predictive analytics, early disease detection, and the optimization of healthcare workflows. Despite the promising advancements, challenges related to data privacy, ethical considerations, and regulatory frameworks need to be addressed to fully harness the benefits of AI in healthcare.

Dhruvitkumar talati

The main purpose of the research is to develop modern tools for insurance management in the global economic crisis, to make an objective assessment based on a critical analysis of existing ones, to identify situations that could lead to international economic, social and natural threats. It is made some recommendations for the development of insurance calculations for the republic of Uzbekistan. Methods: Methods for reforming modern calculation of insurance tariff are recommended by means of theories of probabilities, statistical and mathematical analysis, and foreign advanced countries practical types of summarizing. Findings: While making an analysis, it has found that modern tools for the insurance management of Uzbekistan are needed. We proved this by the results of the modern calculation of insurance in tables (1-6). For the development of the insurance market of Uzbekistan, it should be analyzed by means of penetration and density of insurance premiums, making the deepest calculation of risks of the economy of Uzbekistan, and using the main principals and formulas of the theory of probability. Conclusions: In the end, we can take some results, and give some recommendations such as using the tools of theories of probabilities can help us find the main risks of economy, its powers of influences of the market economy, statistical and mathematical analysis also add some practical, objective results for making under control of any types of insurance risks.

Ikboljon odashev mashrabjonovich

The very first recruitment for a public relations practitioner in Malaysia was encountered in 1948 and was advertised by the federal government of the British Colony in Malaya. This paper examines the subsequent advertisements after Malaya sought independence from the British colonial government. A total of eleven recruitment advertisements were found before the formation of Malaysia on the 16th September 1963. This paper outlines the advertisers, the titles of positions, as well as their qualifications and duties. The results show that the job requirement mainly came from the federal and local governments. Generally, the duties were related to information services and some specific responsibilities.

Mohammed fadel arandas

One of the unique features of Indian society is prevalence of caste system which was originated thousands of years back to demarcate the people engaged in different occupation or jobs. Initially it was not much rigid but gradually people belonging to upper castes for their own selfish means to maintain their monopoly made this arrangement hereditary and started treating people of lower castes disgracefully. For preservation of this system, people started controlling their women to prevent inter-caste marriages and the concept of endogamy came up. This robbed away many types of freedom from women. For women belonging to lower castes, this situation is worse as they are doubly subjugated on the basis on caste as well as gender. Men belonging to their own caste treat them as secondary beings. This paper throws light on this intersection. How intersection of these two kinds of inequalities place them at the lowest position in Indian society. Dr. B.R. Ambedkar rises as their leader who all his life worked for empowerment of downtrodden section of society. He argues that education is the primary tool for evading these differences among people. He further emphasizes to adopt the concept of exogamy to break the backbone of Indian caste system and to immediately leave a religion or culture which legitimizes such system of inequality among people of the same land.

Swati sharma

Background Covid-19 pandemic has hit many countries and put the majority of the public health system to test globally. Mandatory use of face mask was among policies set by the government to contain the spread of the novel disease. But citizens’ attitudes and compliance with these policies are important in controlling the pandemic. We assessed gender-based compliance to Covid-19 protocol (use of face mask) in Jos South, Plateau State, Nigeria. Methods Perception regarding Covid-19 and the use of face masks were assessed among participants using a questionnaire-based survey. In a cross-sectional study, ninety (n=90) questionnaires were administered to willing participants directly. A Chi-square test was used to determine the descriptive analysis of all responses, P-values <0.05 were considered statistically significant. Result Out of 90 participants, 55.6% (50/90) were male and 44.4%(40/90) were female. Forty-two (84%) males deny the existence of the pandemic while in females, 14 (35%) deny that Covid-19 exist. Thirty-seven (74%) of the male respondents do not comply with to use of the face mask and use a single face mask multiple times without decontamination. In females, 28 (70%) comply with the use of the face mask. Unlike the men, 20 (50%) of the females always decontaminate the face mask. The middle-aged adult (26-45 years) uses the face mask more than the young (18-25 years). There was a significant association of gender in relation to the perception of Covid-19 and the use of facemask (p< 0.05). Conclusion Male respondents showed an irresponsible attitude complying to Covid-19 protocol than the females, therefore, enlisting them as a risk factor for the continued spread of the virus. We recommend that public health awareness and campaigns should focus and employ greater influence on men and young adults in their compliance with the preventive protocols.

Bitrus inuwa

The purpose of this study was to determine the attitudes, expectations, experiences, and barriers that physicians in Tripoli hospitals experienced when working alongside Clinical Pharmacists (CPs). A descriptive self-administered questionnaire was used for the study, and participants were selected from several Tripoli hospitals. Most of the respondents agreed that CPs are an essential part of patient care teams and that they have the legal authority to review a patient's medication regimen and response. More than half of respondents believe CPs must be responsible for the medications they prescribe to patients. Half of the respondents agreed that CPs should be encouraged to play a more active role in hospitals and other healthcare facilities. The majority of participants agreed that CPs should participate in managing drug side effects and almost half agreed that CPs can contribute to decisions about drug interactions. By a low agreement rate, 42.7% of respondents thought CPs were specially qualified to counsel patients on drug therapy. A similar low trend was observed, with 40.9% agreeing to provide pharmacists with additional responsibility and authority in clinical departments, in contrast, 54.5% expressed their concern about the clinical responsibility of CPs in clinical practice. A minority of physicians agreed that Physicians should consult pharmacists in selecting the best pharmacological treatment. At the same time, the majority think that pharmacists lack clinical skills and 61.8% feel that physicians are unable to communicate effectively with CPs. 43.6% acknowledged that the traditional opposition between the two professions was a barrier to interprofessional collaboration while the absence of pharmacy space in clinical settings was cited by 39.1%. A majority of respondents agreed that physicians and pharmacists may improve their interprofessional collaboration by raising their awareness about it. A minority of respondents thought that laws and regulations governing physician collaboration should be put in place to promote effective collaboration between physicians and CPs. The study discovered that although most physicians endorse the introduction of clinical pharmacy services in hospitals and believe that physicians and pharmacists can collaborate on many tasks, respondents were not as impressed with the CPs' performance and believed that they lacked the professionalism required to carry out clinical responsibilities successfully. To facilitate the growth of clinical pharmacy services, laws and regulations must be put in place.

Mediterranean journal of pharmacy and pharmaceutical sciences

Right of entry to finance, especially by the poor and susceptible groups, is an essential indispensable for employment, economic development, poverty mitigation and social up-liftment. Here lies the importance of financial inclusion. Financial inclusion or inclusive financing is the deliverance of financial services at affordable costs to sections of disadvantaged and low income segments of the society. The Government of India has taken a number of initiatives so that the banks can serve the poor in a hassle-free manner. With a view to spreading the services to poor and weak groups Andhra Bank plays a vital role in financial inclusion. Keeping this view, the authors have attempted to discuss the role of Andhra Bank towards Financial Inclusion as the main purpose of this paper. It also analyses the performance of the Andhra Bank in terms of its deposits, advances, income, expenditure, profitability etc..

Dr tatayya bommali

Objective: Pyrazolopyrimidines are heterocyclic molecules containing nitrogen as the main composition, and hence, they exhibit pharmacological efficacy. They are analogs of purines so that possessing wide applications in the field of medicinal chemistry. The main objective of this study is to synthesize different derivatives of pyrazole-pyrimidine classes by adopting simple methodology as well as by employing green chemistry. The purpose of the synthesis of these molecules is to study the antitumor activity against Ehrlich ascites carcinoma (EAC) cell lines. Methods: After literature studies, it makes us to involve in the research of synthetic organic chemistry, especially to synthesize new compounds of pyrazolopyrimidines. We are reported solvent-free synthesis of pyrazolo [3,4-d]-pyrimidine-thiones through ethyl acetoacetate, hydrazine hydrate, thiourea, and different benzaldehydes. An ionic liquid 2-methyl-imidazolium-oxalate catalyzed the reactions under ultrasonication bath. Both conventional and ultrasonic methods were employed and comparison studies have been made. It was found that ultrasonic method completed the reaction quicker than the conventional method. All the synthesized compounds were confirmed their structures by 1 HNMR, Fourier transform infrared, 13C-NMR, and elemental analysis spectra. The compounds were tested for in vitro anticancer activity against EAC cell lines. Most compounds revealed significant anticancer activity relative to doxorubicin as a positive control with inhibitory concentration (IC50) values. Results: Ultrasonication method is a simple method under which all the reactions were completed at faster time (<7 min) compared to the convention method. Among eight molecules, 8a and 8d completed the reactions at a faster rate. We reported IC50 values of all the molecules, in which 8e and 8g were exhibited excellent potency against EAC cell lines at different concentrations .

Dr ganesh n yallappa

Industrial waste is one of the most essential sources of contamination in the environment. Chromium (Cr) is a toxic heavy metal, a major contaminant in tannery wastes and its accumulation in soil and water is a major environmental concern today. In the present study, an attempt was made and investigated the status of different beneficial microbes particularly plant growth promoting rhizobacteria (PGPR) from tannery sludge samples collected from tannery effluent treatment plant at Dindugal, Tamil Nadu, India. Experiments were conducted and evaluated their chromium heavy metal tolerance abilities and plant growth promoting activities under in-vitro. Based on molecular analysis, the PGPRs were identified as Achromobacter xylosoxidans (LK391696), Azotobacter vinelandii (LK391702) and. The production of IAA was found to be high by Achromobacter xylosoxidans (46μg/ml) followed by Azospirillum lipoferum (30μg/ml). Phosphate solublization activity was also found to be positive in all these PGPR isolates. Significance of these results revealed that there is a possibility of using these potential PGPRs for bioremediation of chromium contaminated sites and also as good plant growth promoter.

Dr. saranya devi k

The National Education Policy 2020 (NEP 2020) aims to modernize India's higher education system by prioritizing the learner, increasing accessibility, and fostering inclusivity. It emphasizes the importance of libraries as information hubs and libraries, with the policy focusing on their resources and facilities. The policy requires sufficient library employees to manage facilities, create suitable career courses, and foster cooperation between educational institutions and libraries. Infrastructures for libraries are crucial for adult education, lifelong learning, and study. Schools, school complexes, and public library locations should be well-designed and equipped with information and communication technology. Central and state governments are responsible for creating and funding libraries, ensuring they are available and reasonably priced for everyone in the nation. Digital libraries and online resources are included in the NEP 2020, with efforts to improve accessibility online and expand the reach of digital libraries. The policy also includes provisions for enhancing all current libraries, establishing reading rooms and rural libraries in underprivileged areas, making reading materials in Indian languages widely accessible, opening child-friendly and transportable libraries, creating social literary societies, and promoting better partnerships between educational institutions and libraries. The government is focusing on providing top-notch online resources for education, including digital resources, online courses, applications, satellite TV channels, online books, and IT-equipped libraries and Adult Education Centers across India. The policy has significantly raised the standard of instruction in India's higher education establishments, providing students with a more comprehensive and holistic education. Preliminary findings suggest that the policy has had positive effects, but significant human, material, and technological resources are needed for its success. The policy also seeks to increase diversity in higher education by providing financial aid and scholarships to underrepresented groups.

Dr. awadhesh singh gautam

Ever-growing era of mobile and personal wireless networks, motivated research in several fields of engineering resulted in low power and low cost consumer products. The voice band processing required in mobile applications demand for architectures, which can easily be integrated in single chip SoC applications. The conventional approach is to have a dedicated IC outside the digital ICs to perform analog to digital conversion. The motivation of single chip radios demand for integration of such ADC modules on digital cellular related ICs. Mixed signal design is very challenging and hence usually it is preferred to have separate ADC chip before the ASIC/FPGA. In this paper we present a digital sigma delta ADC architecture, which can perfectly be integrated in any digital IC with a targeted sampling rate of 20 kS/s with more than 80 dB dynamic range.

P.a. harsha vardhini

Therapeutic nucleic acids demand specificity and accuracy in design as well as delivery strategies used in replacement or silencing of the target gene. Gene therapy is believed to be the therapy in which the root cause of the diseases can be treated at the molecular level. Generally gene therapy helps in the identification of the origin of the disorder instead of using drugs to diminish or control the symptoms. The application of nucleic acids to treat and control diseases is known as “gene therapy.” Gene therapy consists on the substitution or addition of a functional gene into the nucleus of a living cell, in order to treat a disease or repair a dysfunction, caused by this gene failure. This therapy is used to correct defective genes, which are responsible for genetic diseases. Thus, gene therapy can be used to prevent, treat or regulate hereditary or acquired disorders, by the production of therapeutic proteins. The gene therapy is mediated by the use of viral and non-viral vectors to transport foreign genes into somatic cells to restorative defective genes. This review focuses on viral vectors in detail.

Dr.p.v.kamala kumari

Background: Exposure to cigarette smoke has been associated with pulmonary and reproductive dysfunctions; inflammatory response, oxidative stress and oxidative DNA damage induced by polycyclic aromatic hydrocarbons (PAHs) present in cigarette smoke have been implicated in the pathogenesis of these disorders. The peak expiratory flow rate (PEFR), a biomarker of inflammation and oxidative DNA damage (8-hydroxy-2-deoxyguanosine (8-OHdG), tumor necrosis factor alpha (TNF-α)), reproductive hormones (testosterone (TST), luteinizing hormone (LH), follicle stimulating hormone (FSH)) cotinine and urinary PAH metabolite (1- hydroxypyrene (1-HOP)) were estimated in male active smokers. Methods: One hundred men aged 20-47 years, comprising 50 active male smokers and 50 non-smokers, were randomly recruited into this comparative cross-sectional study. The PEFR was measured using a peak flow meter, serum levels of cotinine, FSH, LH, TST, TNF-α, and urine 8-OHdG by enzyme-linked immunosorbent assay and 1-HOP by high-performance liquid chromatography. Data analysis was done using a t-test and correlation analysis at p≤0.05. Results: Smokers had significantly higher cotinine (49.73±31.76 versus 0.51±0.69 ng/ml, p≤0.001), 8-OHdG (16.34±12.10 versus 5.79±2.14 ng/ml, p≤0.001) and lower PEFR (309.20±56.05 versus 452.80±45.76 L/min, p≤0.001) and LH (5.75±2.06 versus 6.97±2.79 mIU/ml, p=0.015) compared to non-smokers. Duration of exposure to cigarette smoke correlated positively with cotinine (r=0.937, p≤0.001) and 1-HOP (r=0.813, p≤0.001) while cotinine correlated positively with 1-HOP (r=0.863, p≤0.001) only in smokers. Conclusion: Reduced lung function and luteinizing hormone and concurrent increase in oxidative DNA damage associated with exposure to cigarette smoke may suggest the involvement of PAH-induced DNA damage in the development of pulmonary and reproductive impairment in smokers.

Eworo raymond

While playing the Pathfinder RPG, the Game Master describes the events that occur in the game world, and the players take turns describing what their characters do in response to those events. Unlike storytelling, however, the actions of the players and the characters controlled by the Game Master (frequently called non-player characters, or NPCs) are not certain. Most actions require dice rolls to determine success, with some tasks being more difficult than others. Each character is better at some things than he is at other things, granting him bonuses based on his skills and abilities. Whenever a roll is required, the roll is noted as “d#,” with the “#” representing the number of sides on the die. If you need to roll multiple dice of the same type, there will be a number before the “d.” For example, if you are required to roll 4d6, you should roll four six-sided dice and add the results together. Sometimes there will be a + or – after the notation, meaning that you add that number to, or subtract it from, the total results of the dice (not to each individual die rolled). Most die rolls in the game use a d20 with a number of modifiers based on the character's skills, his or her abilities, and the situation. Generally speaking, rolling high is better than rolling low. Percentile rolls are a special case, indicated as rolling d%. You can generate a random number in this range by rolling two differently colored ten-sided dice (2d10). Pick one color to represent the tens digit, then roll both dice. If the die chosen to be the tens digit rolls a “4” and the other d10 rolls a “2,” then you've generated a 42. A zero on the tens digit die indicates a result from 1 to 9, or 100 if both dice result in a zero. Some d10s are printed with “10,” “20,” “30,” and so on in order to make reading d% rolls easier. Unless otherwise noted, whenever you must round a number, always round down. As your character goes on adventures, he earns gold, magic items, and experience points. Gold can be used to purchase better equipment, while magic items possess powerful abilities that enhance your character. Experience points are awarded for overcoming challenges and completing major storylines. When your character has earned enough experience points, he increases his character level by one, granting him new powers and abilities that allow him to take on even greater challenges.

Kamal singh

In the Indo-Pak subcontinent, the traditional systems of medicine, both Ayurvedic and Unani, are primarily based on herbs and herb-based preparation for therapy. Therefore, the importance of the herbal identification process remains critical in achieving the desired and successful therapeutic effect. To support the manufacturers and practitioners of both systems, many herbs are still collected from wild sources, as herbal farming is not very developed in this part of the world. During a survey program conducted in different areas of Pakistan, significant lacks and gaps were noted to be present in the identification & characterization of herbs, which needs to be addressed and fulfilled as many species look alike apparently or physically but have different biological or pharmacological activity. Based on this objective and approach, Centella asiatica was selected for the pharmacognostic and preliminary phytochemical investigation to establish a better correlation and to provide useful methods in its identification as the use of Centella asiatica is very common in Pakistan and other South Asian countries for CNS disorders therapy. Therefore, this study aimed to develop & report some and rapid identification methods for Centella asiatica. The present study includes physical, physicochemical, preliminary phytochemical and fluorescence analysis. For the first time, in the present study, NIR and FT-IR spectra of Centella asiatica have been reported for identification. The findings of the present study are quite promising and can be helpful for the manufacturers and researchers in the identification and development of Centella asiatica-based new drugs or formulations.

Dr. salman ahmed

One of the most important challenges for a company is to manage its supply chain efficiently. One way to do this is to control and minimize its various logistics costs together to achieve an overall optimization of its supply network. One such system that integrates two of the most important logistics activities, namely inventory holding and transportation, is known as the inventory routing problem. Our replenishment network consists of a supplier that uses a single vehicle to distribute a single type of item during each period to a set of customers with independent and deterministic demand. The objectives considered are the management of supplier and customer inventories, the assignment of customers to replenishment periods, the determination of optimal delivery quantities to avoid customer stock-outs, the design and optimization of routes. A genetic algorithm (GA) is developed to solve our IRP. Different crossover structures are proposed and tested in two sets of reference instances. A comparison of the performance of different crossover structures was established. Then, it was used to find the most appropriate crossover structure that provides better results in a minor computation time. The obtained results prove the competitiveness of GAs compared to literature approaches, demonstrate the performance of our approach to best solve large scale instances and provide better solution quality in fast execution time.

Mohamed salim amri sakhri