Learning is a conscious effort made by individuals to acquire various kinds of abilities (competencies), skills (skills), and attitudes (attitudes) through a series of learning processes that will ultimately result in behavioral changes in the individual. The learning process in schools tends to emphasize the achievement of changes in cognitive (intellectual) aspects which are carried out through various forms of approaches, strategies, and certain learning models. Learning systems that specifically develop affective abilities have received less attention, affective abilities are only used as a nurturing effect. This study aims to (1) find out whether online learning is able to bring out the affective abilities of prospective study program teachers (2) analyze the affective abilities of prospective teachers in online learning. The data used in this study is qualitative data. The technique used is a questionnaire. This questionnaire was given to respondents, namely students of PGSD teacher candidates at Muhammadiyah University of Pringsewu. The results of the study indicate that affective abilities can appear in online learning as evidenced by the results of the questionnaire that has been given to respondents. The indicators of affective ability in this study include attitudes, interests, self-concept, values, and morals, all of which are in the good range. This means that the results of students' affective abilities can be said to be valid or appear in online learning
The present review was written to describe the effects of the COVID-19 pandemic on followup and treatment process of gynecological cancers and breast cancer in accordance with current literature, guidelines from national and international cancer associations. Recommendations were provided based on the consensus conference model. In the follow-up and treatment process of gynecological cancers and breast cancer, there are many factors, such as the clinical course of patient, the possibility of an emergency of the patient, the stage of the cancer and the current status of the chemotherapies. Although opinions in all types of cancer differ among themselves, general beliefs are postponement of non-urgent surgical operations, re-evaluation of chemotherapy processes, postponing appointments for new nonurgent diagnoses, reducing the length of hospital stay of patients in emergency procedures, conducting consultations by telemedicine or telephone, treatment of patients with COVID-19 suspicions after 15 days, planning biopsies or surgeries according to the staging status of cancers and planning conferences as video conferences in cases that require a multidisciplinary approach. Patients diagnosed with cancer during the COVID-19 pandemic should not be lost, followup and treatment should be continued without disruption, patients should be remembered to be in the high-risk group in this process and necessary hygiene measures should be taken in both follow-up and treatment concerning risks and COVID-19 pandemics.
Internet of Things (IoT) enhances the global connectivity to all the remote sensing devices. It enables the connectivity of communication and processing the real-time data that has been collected from an enormous number of connected sensing devices. There is an increase in the IoT technology that leads to various malicious attacks. It is more important to overcome the malicious attacks, mainly to stop attackers or intruders from taking all the control of devices. Ensuring the safety and accuracy of the sensing devices is a serious task. It is very much important to enabling the authenticity and integrity to obtain the safety of the devices. Dynamic tree chaining, Geometric star chaining and Onion encryption are the three solutions that has been proposed in this project for in order to enable authenticity and integrity with information hiding for secure communication. The simulation results are driven displays that the proposed system is very stable and much better than other existing solution in means of security, space and time.
This study investigated the practice of artificial fruit ripening among fruit vendors of banana, plantain, mango and pawpaw in Rivers State. The study adopted a descriptive cross-sectional survey design. Two objectives, corresponding research questions and null hypotheses guided the study. The population for the study comprised all the accessible 1,810 fruit vendors in Rivers East senatorial district. A sample size of 472 fruit vendors was drawn using multi-stage sampling procedure. A validated self-structured questionnaire titled ‘Practice of Artificial Fruit Ripening’ with inter-scale reliability co- efficient of 0.896 was used as instrument for data collection. The descriptive statistics of mean and standard deviation were used to answer the research questions, while inferential statistics of Z-test and One-Way Analysis of Variance were used to test the hypotheses at 0.05 alpha level. It was found that fruit vendors in Rivers State sometimes practiced artificial fruit ripening using chemical and non-chemical methods. It was also discovered that regardless of their level of education and years of experience in the fruit business, the fruit vendors sometimes indulged in unhealthy practice of artificial fruit ripening. More so, the study revealed significant difference in practice among the fruit vendors in Rivers State based on level of education and years of experience. Based on the findings, it was concluded that the current practice of artificial fruit ripening in Rivers State is not in tandem with global best practices and therefore portend danger to the wellbeing of Rivers people and other Nigerians. The study therefore recommended among others that; community health workers should carry-out regular and effective health awareness campaigns concerning the dangers of using chemicals to ripen fruits. The Government of Rivers State through the Ministry of Agriculture should organise training programmes for fruit vendors on faster, safer, and economically feasible methods of fruits ripening and other post-harvest management techniques
During the 16th century, firearms played a transformative role in Indian warfare, considerably enhancing the effectiveness of the Mughal army. The introduction of muskets and artillery by Babur in 1526 revolutionized military strategies, giving the Mughals a decisive advantage in battles and sieges. The Mughal army’s structure, particularly under Akbar’s Mansabdari system, centralized control and ensured a loyal, efficient military force. This technological and organizational superiority enabled the Mughals to consolidate power over diverse regions through a combination of military might and diplomacy. By the 17th century, there was a significant change in rebellions as firearms started being used by peasants. This shift in weaponry fundamentally altered the nature of these uprisings, empowering the peasantry in new ways to resist authority. Multiethnic regional powers also recognized the importance of firearms, acquiring them from the Mughals or Europeans, and employing them effectively in battles. In the mid-18th century, the Marathas and later the Mysore Sultanate took a notable step by establishing arms factories and engaging European experts to produce advanced firearms. This marked a departure from the past, where regional powers typically relied on the Mughals or European companies for firearm procurement. This shift toward domestic arms production signaled a move toward greater self-sufficiency and the development of advanced firepower. By the 18th century, the Mughal Empire was in decline, and multiethnic regional powers and European colonial forces, equipped with advanced firearms, challenged and eventually overshadowed Mughal dominance.
The present review shares updated data on the botany, distribution, traditional medicinal uses, phytochemistry and pharmacology of Macrotyloma uniflorum (Lam.) Verdc. All provided information was obtained through Google Scholar, Pubmed, SciFinder, Scirus, Web of Science and a library search.
The conservation of traditional medicinal knowledge opens the door towards modern aspects of herbal drug discovery. It started with knowledge exchange through ethnic groups through oral tradition and then in the documented form. Herbaria conserving identified and authenticated plants for future correspondence play an important role. In presenting the review, the authors have declared different auxiliary aspects of herbaria for phytomedicinal research.
Petroleum refineries are largest chemical industries that are responsible for emission of several pollutants into the atmosphere. Benzene and its metabolites are regarded as the most hazardous compounds that are emitted by petroleum refineries. These contribute to toxic oxidants, which cause many serious health risks to petroleum refineries workers. This study was aimed to analyze the effects of chemical exposure on hematological and biochemical parameters among workers at Zawia oil refinery and Mellituh oil and gas refinery companies. A total of 200 workers participated in this study which consisting of two equal groups (each group: n = 100). The first group consists of petroleum refineries workers and the second group consists of non-oil work civil servants serving were recruited as exposed and control subjects, respectively. The results of blood picture, liver enzymes and kidney functions were compared between the groups. Mean white blood cells counts, platelet counts, and hematocrit count were significantly higher, while the mean red blood cells count was insignificantly changed in petroleum refineries workers. While the mean hemoglobin and corpuscular hemoglobin concentration levels were significantly lower, whereas the mean corpuscular volume and mean corpuscular hemoglobin levels were insignificantly changed in petrol refineries workers. Liver enzymes and renal functions were significantly higher in petrol refineries workers. The present findings indicate that occupational exposure to benzene causes significant alterations in hematological and biochemical parameters and workers are at high risk of developing blood, hepatic or renal related disorders. Protection and frequent medical attention should be given to petroleum refineries workers.
Mediterranean journal of pharmacy and pharmaceutical sciences
Introduction: In Bangladesh, diabetes mellitus (DM) is a significant health concern contributing to numerous complications that enhance the mortality risk. This study aims to examine the impact of lifestyle patterns, socioeconomic conditions, and comorbidities among diabetic patients to establish valid associations between variables. Methods: A cross-sectional study was carried out among 450 patients with diabetes mellitus at the outpatient department of different hospitals in Bangladesh. Data collection was done through face-to-face interviews using a structured questionnaire. Results: The study analyzed sociodemographic and lifestyle traits among diabetic patients, categorized by gender and results were based on unadjusted analysis. Men had a higher prevalence of being married (99.4%) compared to women (97.9%). Women were more common in rural areas (67.5%) and less likely to own smartphones (12.3%, vs 24.7% for men). More women were overweight (31.2%) and owned house (92.1%). Clinical symptoms showed no significant gender associations except for headaches, more prevalent in women (OR=0.65; p=0.034). Women had a higher prevalence of cardiovascular disease (48.3%, vs 35.4% for men, OR=0.59; p=0.009), while kidney dysfunction was more prevalent in men (16.5%, vs 9.6% for women, OR=1.86; p=0.032). Allergic problems (20.5%, OR=0.40; p=0.014) and asthma (5.5%, OR=0.22; p=0.029) were more common in women. No association was observed in the occurrence of ulcer with the respondents’ gender. Regarding lifestyle, 50.7% of respondents consumed rice more than once daily, 71.8% did not smoke, and most (59.1%) had a normal BMI. Conclusions: Based on our study findings, men should focus on renal health by refraining from high-glycemic meals, while women should concentrate on managing their weight and cardiovascular health by utilizing modern healthcare facilities.
Hypertension is a public health issue that significantly increases the risk of health problems and decreases health quality of life of the patients. Angiotensin converting enzyme inhibitors are used to control hypertension by preventing production of angiotensin II in turn decrease blood pressure, thus it may enhance the quality of life. This study aims to assess the effect of angiotensin converting enzyme inhibitors on the quality of life of patients with hypertensive aging 40 years or older in Benghazi city in comparison with other classes of hypertension medications. A case control observational study was conducted, adopting the structured face-to-face interviewing survey technique. Over 150 patients who visited Benghazi medical center during the study period (November, 2019 to March, 2020), to follow up their chronic disease. The investigators used a pre-validated, pre-piloted questionnaire that has been adopted from SF 36 and modified according to the updated literature review; responses to each question were coded and analyzed. The results display that antihypertensive medications were found to be significantly related to the limitation on the physical activity domain and found that medications decrease the limitation on the activity with about 20% of the patients who taking angiotensin receptor blockers (20%) and 30% of the patients taking angiotensin converting enzyme inhibitors, 40% of the patients had no limitations on bending kneeling and stooping. Moreover, on the limitations on walking more than one kilometre, the results were about 15% of the patients taking angiotensin receptor blockers and 30% of the patients taking angiotensin converting enzyme inhibitors had a slightly or no limitation on walking more than a kilometre. Thus, the findings indicate that antihypertensive medications have a positive effect on quality of life of the patient in limitation on activity domain but no conclusive difference was found between angiotensin converting enzyme inhibitors and angiotensin receptor blockers medications.
Mediterranean journal of pharmacy and pharmaceutical sciences
Provision of clean water is one of the United Nations Sustainable Development Goals. Water quality assessment as an ongoing exercise, in view of the threat of contamination from natural sources and human activities, plays a pivotal role in the sustainable management of water resources. Potable water samples were collected from Enugu Metropolis for water quality assessment. The physicochemical parameters were determined using APHA (1995 - 1998) protocols, and the presence of 7 heavy metals (Chromium, Zinc, Manganese, Silver, Cadmium, Iron and Lead) in the waters were determined using Atomic Absorption Spectrophotometer (AAS). The results of the physicochemical analysis of the four samples show a pH range of 8.60 - 8.95mg/l; this result showed that pH of the water samples were slightly alkaline and above the WHO stipulated range of 6.50 - 8.50. Acidity ranged from 5.00 - 6.88mg/l, while alkalinity values were between 7.52 - 13.00mg/l. The total dissolved solid (TDS) and total solids (TS) was present in very minute quantities and below their permissible limit of 0.45mg/l; while total suspended solid (TSS) was not present at all. The heavy metal analysis showed that all but 2 heavy metals (Cadmium and Lead) were below the permissible standard set by the WHO in all four samples. Cadmium was present in samples A and C with values 0.021mg/l and 0.006mg/l respectively, which is above its WHO limit of 0.005mg/l; while Lead was present in samples A, B and C with values of 0.021mg/l, 0.011mg/l and 0.015 mg/l respectively, which were above the WHO limit of 0.010mg/l. Given the well-documented toxicity of certain metals, there is a need for safety checks to be carried out in potable water companies to address the source of this contamination and ensure production of safer drinking water.
The incorporation of lomustine, a hydrophobic anticancer drug into PLGA nanoparticles by interfacial deposition method was optimized. Based on the optimal parameters, it was found that lomustine-PLGA nanoparticles with acceptable properties could be obtained. Optimization of formulation variables to control the size and drug entrapment efficiency of the prepared nanoparticles seems to be based on the same scientific principles as drug-loaded nanoparticles prepared by nanoprecipitation, solvent evaporation method. The process was the most important factor to control the particle size, while both the drug-polymer interaction and the partition of drug in organic and aqueous phases were the crucial factors to govern the drug entrapment efficiency. PLGA concentration at lower level (100 mg), 1:5 organic phase: aqueous ratio, 1%w/v PVA concentration, 3%w/v pluronic F68 achieved smaller particle size. Additionally, L:G ratio of PLGA 75:25, lower volume of organic solvent (1:10 organic phase: aqueous phase), higher initial drug content (10mg) enhanced the drug entrapment efficiency and maintained lomustine concentration in blood for an extended time period, elevated lomustine concentration in lungs and slowed the elimination of lomustine. The biodistribution profiles of prepared nanoparticles in albino mice showed higher plasma drug concentration for longer period of time, elevated drug concentration in lungs and slow elimination from kidney. No toxic effects of prepared nanoparticles were observed in histopathological examination of lungs and kidney. The systematic investigation reported here promises the development of PLGA nanoparticles loaded with lomustine when tested in Lung Cancer cell line L132 and toxicological/ histopathological studies in albino mice.
Recent reports showed an association between bariatric surgery and the development of acute pancreatitis. This report presents a case of acute pancreatitis following a laparoscopic sleeve gastrectomy (LSG) in a 24-year-old Indian female patient, who presented to the Emergency Department at Hamad General Hospital, Qatar, with severe epigastric pain and persistent vomiting 13 days after LSG. She was diagnosed with acute pancreatitis based on a high level of lipase greater than three times the upper limit of normal, and a computed tomography scan of the abdomen, which was consistent with acute pancreatitis. The patient was treated conservatively with a significant improvement in her symptoms and laboratory tests throughout her admission and consequently was discharged.
Conservation agricultural (CA) practices prove to be beneficial in terms of resource utilization and maintenance of soil health. Rice-Wheat cropping system (RWCS) is the majorcropping system in Indo-Gangetic plains of India. CA practices are becoming popular in this cropping system as sustainable agricultural management practices. Phosphorus (P) and potassium (K) are important primary nutrients and are required for crop growth. A field experiment was conducted during the period of 2015-2017 at Taraori village of Karnal district in Haryanato study the effects of conservation agricultural practices on P and K availability as well as uptake in rice-wheat cropping system. The experiment comprised of four treatments i.e. Transplanted rice + Conventionally tilled wheat (T1), Direct seeded rice + Zero tilled wheat with residue retention (T2), Transplanted rice + Zero tilled wheat (T3) and Transplanted rice + Zero tilled wheat with residue retention (T4). Results showed that P uptake was highest in T4 treatment in wheat crop. P uptake in rice was highest in T4 treatment while direct seeded rice (T2) showed lowest P uptake. CA practices also increased K uptake in both the crops. Practicing zero tillage in wheat increased the availability of soil phosphorus as compared to conventionally tilled treatment with highest value (34 kg ha-1) recorded in T3 treatment. But direct seeded rice soil showed lower values of soil available P. Similar to phosphorus, available potassium of soil also increased in all treatments. Highestvalue (341.5 kg ha-1) of available K was recorded in T4 treatment while it was minimum (307.2 kg ha-1) in T1. Residue incorporation in soil led to more availabilityof K in T2 and T4 treatment. This study features the significance of conservation agricultural practices over conventional practices in terms of increasing the uptake and availability phosphorus and potassium in soil. Key words : Conservation agriculture,
The unprecedented global effort to develop and distribute COVID-19 vaccines has highlighted remarkable scientific achievements and persistent inequities in access across populations. Analyzing of regional vaccine deployment patterns reveals critical insights into pandemic response dynamics, shaped by manufacturing capacity, regulatory frameworks, procurement strategies, and regional health priorities. Data from WHO regions (Africa, the Americas, Eastern Mediterranean, Europe, and Western Pacific) demonstrate significant disparities in vaccine types and suppliers, underscoring the complexity of global vaccination efforts. (Figure 1) illustrates this regional vaccine distribution by WHO regions.
Natural products, the most significant source for pharmaceutical development, have been investigated and utilized to alleviate diseases since early human history. The currently accepted modern medicine from different natural products has gradually developed over the years and is God's gift in the sense of traditional knowledge. Trustful humanity believes that drugs can cure every ill of natural origin. Natural medicines, prevalent in holy books, folklores, Materia medica and other historical literature, have become an essential domain of modern pharmaceutical sciences. Natural compounds from terrestrial and marine organisms have been extensively used to treat many diseases in their natural form or as a template for synthetic modification. Several of these natural products have shown biological and pharmacological activities and serve as the starting point in the development of modern medicines. Screening of crude plant extracts opens the door to the discovery of novel bioactive compounds, and elucidation of their structures leads towards new synthetic preparations, which can be administered in reproducible, accurate doses for particular therapeutic purposes. However, what is needed are rapid screening techniques, structure-based design, bioactivity-safety evaluation, extraction and isolation, and clinical trials for drug development under innovations, which will share the profit of products derived from natural origin. The government sector, industries, and academic institutions also play an essential role in developing biological drugs for human health enhancement. This book comprises four chapters. The first chapter is related to urolithiasis. In this chapter, the types of urinary stone formation in humans, their mechanism, current antiurolithiatic strategies and their complications are discussed precisely and comprehensively. Chapter two declares urinary stone treatment in early civilisation. The third chapter is about globally used antiurolithiatic plants. This chapter is a treasure trove of information covering the importance of plants in combating urolithiasis, their diverse pharmacology, and a comprehensive list of 888 antiurolithiatic plants from 144 families used in 55 countries. The tabular format provides a clear understanding of their historical background, mechanism of action, therapeutic spectrum, and formulations with doses. Hopefully, this book will not only be helpful for the general public but also attract the scientific world to antiurolithiatic drug discovery. This valuable ethnopharmacological information will provide opportunities for the future research and development of new natural antiurolithiatic compounds. We extend our heartfelt gratitude to all the teachers, colleagues, and institutions whose unwavering support and encouragement made this book possible. We reserve a special thanks for the acquisition Editor of LAP Lambert Academic Publishing, Germany, whose inspiration and support were invaluable.
Flow control techniques are broadly classified into two types 1.passive control 2.active control. Present paper discuss about the experimental investigation of flow control using passive method on bluff body. Authors also explains about the various flow control techniques used in bluff body aerodynamics. Experimental setup consists of L m span and diameter d of cylinder model. The next model is having strip of cross section 0.01d dia is placed on the cylinder along the span wise distance with equal polar distance around 30o. both the models were kept between four walls in a Reynolds number ranging from 10000 to 15000. The results show that the Cp values changes according to the changes in cylinder roughness.
Youth entrepreneurship contributes to the social, cultural, and economic development of society, especially in many developing countries. The idea of encouraging young people to start businesses for a variety of reasons is now widely encouraged. However, there are many challenges and doubts faced in starting a business particularly after the Covid-19 is over. Therefore, the community service was carried out by lecturers at Business School, Universitas Pelita Harapan Medan Campus, providing the onsite seminar and training to 70 high school students at Santo Nicholas School in February 2023. The purpose of the community service was to encourage the students to plan their business projects by presenting data and information on the latest trends and issues in entrepreneurship and finance, as well as conducting one-to-one sessions with the students. Most of the students were enthusiastic throughout the activities resulting in several business plans and proposals being created at the end of the community service. It is implied that young people are indeed motivated to begin their entrepreneurship journey and school is the right place for them to acquire the necessary knowledge and skills. Teachers and parents are suggested to continue to assist the students by providing the commitment and funding required to begin and sustain the business.
Mentoring relationships between a senior, experienced faculty member and a junior employee, between a faculty member and an undergraduate or graduate student, or between a senior and a junior student is essential in higher education. The current review aims to emphasize the necessity of establishing organized mentorship programs at national institutions to enhance academic performance, teaching/learning effectiveness, knowledge and skill development, growth and development, research productivity, and community engagement. The mentor and mentee both benefit from the mentoring relationship. Academic advising, preceptor supervision, and supervision of graduation projects are different from the mentoring relationship as they focus on only one aspect of the relationship, whether it is the study plan, the study session, or the project, respectively. Mentoring is a mutually beneficial relationship that calls for integrity, decency, self-assurance, trust, and respect. Educational institutes and colleges should set up a committee to establish a well-organized mentoring program with all the necessary templates for recruiting mentors and mentees, and also for annual evaluation and feedback from all parties involved.
Mediterranean journal of pharmacy and pharmaceutical sciences
The samples of K1-xNaxNbO3 (X=0.4, 0.2, 0) ceramics (PSN) have been prepared by the conventional solid state reaction method and sintering process. The prepared samples have been characterized by XRD. All the prepared samples show orthorhombic structure at room temperature. Dielectric and Electrical properties of PSN system have been investigated in the temperature range 450C-2450C, and at 1MHz frequency. It is observed that dielectric constant, loss tangent and electrical conductivity increases with increasing temperature. Near the transition temperature dielectric constant, loss tangent and electrical conductivity of these samples show anomalous behaviour with temperature.