Effects of rapeseed oil (rapus indicus) supplementation on omega-3 fatty acid concentration and carcass characteristics in broiler chicken

Dietary fatty acid composition in broiler influences carcass quality by altering fat deposition and fatty acid profile. Thus, the study was carried out to evaluate the effect of incorporation of rapeseed oil in broiler ration on omega-3 fatty acid concentration of carcass and its traits in broiler chicken. A total of 160 day-old straight run broilers (Vencobb 400) were randomly divided into four treatment groups (G1, G2, G3 and G4) having four replicates of ten chicks each. The basal diets (G1) were prepared to meet BIS (2007) nutrient requirements with palm oil at 1.5, 3, and 4.5 per cent in pre-starter, starter and finisher diets, respectively. The experimental diets were broiler rations prepared with rapeseed oil replacing 25, 50 and 100 per cent of palm oil in G2, G3 and G4 diets, respectively. The diets were fed ad libitum till 6 weeks of age. Six birds from each group were randomly selected and slaughtered on 42nd day to study omega-3 fatty acid concentration of carcass and its characteristics. The crude fat content of breast and thigh muscle was significantly (P<0.05) reduced in the group fed rapeseed oil included diets. However, carcass yield, processing yield and meat to bone ratio of cut up parts was not significantly affected. The colour and pH of breast and thigh muscles were similar among the treatment groups. Omega- 3 fatty acid concentration was significantly (P<0.01) increased in both breast and thigh muscle of G4 group broilers compared to G1 group. Thus, rapeseed oil inclusion in diet significantly increased omega-3 fatty acid concentration and significantly reduced crude fat concentration breast and thigh muscles with no effect on the carcass yield and its quality when included in the diet replacing palm oil at different proportion

SENTHIL MURUGAN Senthil murugan

A review on parkinson’s disease

Parkinson’s disease, first described by James Parkinson in 1817, is a neurodegenerative ailment resulting from the damage of nerve cells in the brain. It is a chronic, progressive, neurodegenerative disorder with an estimated prevalence of 31 to 328 per 100,000 people worldwide. It is estimated that more than 1 percent of the population over age 65 are afflicted with Parkinson’s disease; incidence and prevalence increase with age. There are numerous unanswered questions regarding the diagnosis and management of Parkinson’s disease. Worsening mobility, causing problems with activities of daily living, pain and communication problems due to rigidity of facial muscles, are the main reasons of their decreasing quality of life. This study is focused on the role of psychological variables, which could be associated with quality of life in PD patients. After their identification a discussion about opportunities of improvement patient’s quality of life can be opened. Current drug therapies for human PD with Levodopa or various dopamine receptor agonists offer symptomatic relief and appear to have little effect on the neurodegenerative process. More than 50% of patients with PD treated over 5 years with Levodopa will develop complications such as motor fluctuations and dyskinesia’s. In this scenario, slowing the progression of PD through neuroprotective or restorative therapy is a major focus of research. From a pharmacologic standpoint, current strategies involve interrupting the cascade of biochemical events that leads to death of dopaminergic cells. The significance of many indigenous medicinal plants and their phytoconstitutents in the management of Parkinsonism with minimal side effect profile arise in this context

Zeenath Banu Zeenath banu

Antifungal activity of hypnea pannosa j. agardh against aspergillus flavus

The methanol extract of the whole alga Hypnea pannosa J. Agardh was subjected to antifungal screening. It showed low activity against Aspergillus flavus Link ex Gray 1821.

Dr. Salman Ahmed Dr. salman ahmed

Iatrogenic splenic infarction after embolization of an anomalous artery supplying a pulmonary sequestration: a report of a rare case

Iatrogenic splenic infarction is a rare clinical entity that can result from various abdominal surgical and invasive procedures. We report a case of iatrogenic splenic infarction in a 29-year-old female who presented with hemoptysis and was found to have pulmonary sequestration. During the embolization of the anomalous artery supplying the pulmonary sequestration, she developed severe pain and was found to have a splenic infarction, caused by a part of the coil that dislodged during the procedure. The patient showed good response to conservative management and was discharged in good condition.

Karishma Karishma

In vitro microscopic study of calcium hydrogen phosphate dihydrate crystals growth patterns

The study aims to explore the possible morphological features of calcium hydrogen phosphate dihydrate (brushite) crystals on a glass slide. The study was conducted on a glass slide under a microscope to observe the growth patterns. As a result, needle, platy, star shape, and tetragonal bipyramidal crystals were observed. Different patterns of platy crystals, like plates with spatial branches and radiating assemblages of platy crystals, were also found.

Dr. Salman Ahmed Dr. salman ahmed

Impact of energy drink consumption on pattern and quality of sleep among students in libyan international medical university

Consumption of energy drinks was significantly associated with sleep problems, which are progressively used regardless of negative health effects particularly among adolescents and young adults. The goal of this study is to examine the relationship between energy drinks and sleep patterns on college students by more than one parameter. Target number of students was taken to be 1 000 participants and the study reached 434 participants were invited via self-administered questionnaire at Libyan International Medical University students during 2020 and 2021 in all levels which consisted of 20 questions and the main measurements are dependency, negative effect of energy drink and effect of energy drink on sleep. The results showed that the consumption prevalence rate of energy drinks amongst participants is 59.4%. The majority of participants enrolled in this study are male (52.5%) and 47.5% were female students. In conclusion: energy drinks consumption is a risk factor of poor sleep quality between Libyan International Medical University students. An awareness must be increased about energy drinks consumption to confirm the relation to sleep quality and general health.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

Importance of herbaria in herbal drug discovery

The conservation of traditional medicinal knowledge opens the door towards modern aspects of herbal drug discovery. It started with knowledge exchange through ethnic groups through oral tradition and then in the documented form. Herbaria conserving identified and authenticated plants for future correspondence play an important role. In presenting the review, the authors have declared different auxiliary aspects of herbaria for phytomedicinal research.

Dr. Salman Ahmed Dr. salman ahmed

A systematic approach on reducing the energy consumption in green computing

Green computing is focusing on reducing the energy consumption, resource usage, carbon dioxide emission. It was found that Last year, Google used about 12.4 terawatt-hours of electricity. Energy consumption in data centers is reduced by decreasing the resource utilization that is by switching off or shifting the computing nodes to sleep mode. But when the servers are being used the energy consumption is minimized by using energy efficient scheduling and optimization techniques.In WNS the sensor nodes are deployed in remote areas, these sensors are powered by battery that decreases the lifetime, therefore by using energy efficient techniques can increase the uptime of the battery-operated devices in WNS. This work studied various energy efficient techniques that minimize energy consumption usage in Data Centers (DC) and the algorithms that increase the uptime of the battery-operated device in (WNS) Wireless Network Sensors.

Dr H Shaheen Dr h shaheen

Human resource management

Human resource management (HRM) is the process of employing people, training them, compensating them, developing policies relating to them, and developing strategies to retain them. As a field, HRM has undergone many changes over the last twenty years, giving it an even more important role in today's organizations

Zamzam Abdelazim Zamzam abdelazim

Ecofriendly synthesis of pure and modified cumno3: it’s application as gas sensor

Recently, novel materials like gas-sensing metal oxides, mixed metal oxides, and modified mixed metal oxides have attracted great attention owing to their key roles in monitoring environmental pollution, security in hospitals, homes, and public places, and hazardous emissions from industries and automobile exhaust. Initially, the mechanochemical (MCh) method was employed for the synthesis of the CuMnO3 catalyst and then the modification of CuMnO3 through the hydrothermal route. These synthesized catalysts were characterized by Ultraviolet Violet-Diffused Reflectance (UV-DRS) spectroscopy, Fourier Transform Infrared Spectroscopy (FTIR), and Scanning Electron Microscopy (SEM). The average particle size obtained for 3 % Fe/CuMnO3 was found to be 14–28 nm. The present work proclaimed that among all the synthesized 1,3,5 % Fe/CuMnO3 materials, the 3 % Fe modified CuMnO3 material shows significant gas sensing properties towards highly toxic H2S gas released from sewage plants, oil, and natural gas industries, among NH3, CO2, H2S, H2, CO2 and Cl2 with moderate temperature requirements and excellent selectivity.

Shilpa Sangle Shilpa sangle

Arisaema jacquemontii blume (araceae): a review of medicinal uses, phytochemistry and pharmacology

Arisaema jacquemontii Blume (Araceae) is a medicinally important plant for treating different diseases, especially dermatological disorders. Alkaloids, phenols, terpenes, flavonoids, glycosides, and tannins have been reported from this plant. Antioxidant, antifungal, antibacterial and anticancer activities are also shown by Arisaema jacquemontii. The present review attempts to compile all the previous data based on its medicinal uses, phytochemistry and pharmacology reported in the earlier articles.

Dr. Salman Ahmed Dr. salman ahmed

Effect of dietary flavonoids on amine incorporation activity of transglutaminase 2 enzyme

Transglutaminase 2 (TG2) is an inducible transamidating acyltransferase that catalyzes Ca2+-dependent protein modifications. TG2 enzyme disruption has been implicated in several different disease processes and disorders such as Huntington and Parkinson’s diseases, cancers such as breast, ovarian and pancreatic cancers. Coeliac disease (CD) is the one disease state that TG2 activity plays a crucial role. To date, a gluten-free diet is the only accepted form of therapy for CD. Because of the important role of TG2 enzyme in the initiation of CD, therefore, this study was aimed at the identification of TG2 inhibitors from natural sources, as a potential intervention in CD therapy. Competitive amine inhibitors are the most widely used TG2 inhibitors because they are commercially available, chemically stable and relatively non-toxic in living systems. The natural products chosen for this study were dietary flavonoids. Flavonoids were extracted from different food samples. The flavonoids food extracts were subjected to the TG2 activity assays to examine their effect on the enzyme activity. The assays were carried out under optimal conditions of pH, Ca2+ and with N, N-dimethylcasein (acyl-donor) or casein (acyl-acceptor) as acyl-donor substrates and biotin cadaverine (acyl-acceptor) or TVQQEL as (acyl-donor) substrates. TG activity was measured by two different microplate assays, Biotin-labeled cadaverine incorporation assay and Biotin-labeled peptide cross-linking assay. In the TG2 amine incorporation activity, all of food extracts display a significant inhibition effect towards the human recombinant transglutaminase2 (hrTG2) and guinea pig transglutaminase 2 (gplTG2) (20 - 50% of inhibition). While in the TG2 cross-linking activity, the majority of food extracts displayed an inhibition effect on the gplTG2 cross-linking activity (50 - 70% of inhibition) but only the strawberry and kale extracts showed an effect on hrTG2 activity (40 - 50% of inhibition). The inhibition of TG2 activity can be considered as a potential therapeutic target in the treatment of CD.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

Prevalence of tuberculosis in shabwah governorate, yemen: a cross-sectional study

Background: There is a lack of data on current tuberculosis (TB) burden in Shabwah Governorates in Yemen. This study aimed to investigate the prevalence, epidemiology, and outcomes of TB disease in Shabwah Governorate, Yemen. Materials and Methods: This cross-sectional study was conducted at the National TB Program (NTP) Center in Ataq City, Shabwah Governorate, Yemen. The study involved TB patients of different ages who were notified at the center between January 1, 2021, and December 31, 2021. Results: We involved a total of 123 new active TB cases, including 86 (69.9%) with pulmonary TB (PTB) and 37 (30.1%) with extrapulmonary TB (EPTB). The total prevalence of TB disease during the year 2021 was 14.5 new TB cases per 100,000 population, while the median age of the study population was 34 years. The majority of the cases (23.6%) belonged to age group 15–24 years. There was a slightly higher preponderance of males 54.5% (n=67). EPTB was detected in 37 (30.1%) patients with lymph node TB being the most common manifestation [17 (46.0%)]. All patients received four-drug anti-TB therapies for 6–12 months. Most patients 111 (90.3%) were cured, and 2 (1.6%) patients died during the course of the disease, while 10 (8.1%) patients were lost during follow-up. Conclusion: The prevalence of TB in Shabwah Governorate was 14.5/100,000 population. Male patients and younger age groups were more affected, while the lymph nodes were the main extrapulmonary sites involved and the cure rate was 90.2%. The results of the study indicate the need to revise the notification form for active TB cases and to expand NTP activities to focus on targeted screening for active TB cases in high-risk groups to close the gap in unidentified TB cases.

Karishma Karishma

Enhancing hydro power plant efficiency through hybrid optimization approach

The inclusion of hydroelectric power is crucial to Nigeria's overall energy mix, playing a significant role in electricity generation. However, the Shiroro hydro plant, one of the main facilities located on the Kaduna River, is currently facing operational obstacles due to deteriorating infrastructure and inadequate maintenance practices. To overcome these challenges and improve efficiency within Nigeria's hydroelectric power sector, a hybrid-optimization approach has been proposed. This study sought to enhance the efficiency of the Shiroro hydro plant by implementing this innovative method. To achieve our objectives and address pertinent research questions, a mixed research method combining primary and secondary data was employed. The analysis included hydropower modeling and hydro-turbine input-output modeling. Three optimizer models, namely the particle swarm optimizer (PSO), Ant colony optimizer (ACO), and Artificial bee colony optimizer (ABCO), were utilized to formulate objective functions and task representations. The study involved comparing the daily output and fitness response of the Shiroro hydro plant through swarm optimizer iterations. The findings revealed a clear correlation between the turbine's power output and the water flow rate and water column height, suggesting that altering these factors could significantly improve the plant's performance. The comparison of the PSO, ACO, and ABCO models demonstrated that PSO and ABCO generated optimal or near-optimal solutions, while ACO produced suboptimal results. Consequently, the study concluded that enhancing the Shiroro hydro plant's output was feasible by increasing the water flow rate and column height. Additionally, the utilization of PSO and ABCO models proved to be an effective means of accurately predicting the turbine's output. As a result, the study recommended the integration of hybrid optimization techniques to monitor and identify any deviations in the Shiroro hydro plant's daily power output. This approach would enable prompt maintenance to be carried out, preventing significant damage to the plant. Ultimately, this research contributes valuable insights into improving the efficiency and performance of Nigeria's Shiroro hydro plant.

FXintegrity Publishing Fxintegrity publishing

Hydatid cholecystitis: a rare and unexpected diagnosis mimicking acute cholecystitis

Hydatidosis is a parasitic zoonosis caused by the larval form of Echinococcus granulosus, endemic in the Mediterranean basin, the Middle East, and South America. [1] While this pathology primarily affects the liver (50-70%) and lungs (20-30%), [2] vesicular localization is exceptionally rare, representing merely 0.1% of all hydatid localizations. [3] This rarity significantly complicates preoperative diagnosis, often leading to intraoperative discovery.

Karishma Karishma

Uv spectrophotometric determination of cefixime in bulk and its dosage form

A novel, simple, accurate, sensitive, reproducible, economical and less time consuming spectroscopic method was developed and validated for determination of cefixime. The solvent used was 0.1 N HCL and the absorbance maxima or the λmax was found to be 283.0 nm and 303nm for zero order and first order derivative respectively. This method obeyes Beer’s Law for the concentration range of 8–16 µg/ml for cefixime. The proposed method was been validated statistically as per the ICH guidelines for linearity, accuracy, precision, specificity, LOD and LOQ. The method developed and validated successfully for the quantitative analysis of cefixime in bulk and dosage form.

Prasanna Pradhan Prasanna pradhan

Welcome letter from yemen journal of medicine

The past few decades have witnessed several attempts to establish renowned medical journals in the Republic of Yemen. Some of these initiatives were successful but fell short of the researchers’ expectations, because they failed to meet international standards of scholarly writing in the medical field. Recently, the civil war has dashed any hopes of launching such a journal from within the country. We believe that this is the right time to establish a new peer-reviewed medical journal of high standards which meet the expectations of all Yemeni researchers across the board, from both within and outside the country. As a result of enormous efforts, discussions, and extensive collaboration, we have now been able to finalize the structure and content of the Yemen Journal of Medicine (YJM). Files

Karishma Karishma

Prevalence and predictors of traditional medicine use among persons with diabetes in africa: a systematic review

The utilization of traditional medicine (TM) is prevalent among the general population in Africa; however, its use among individuals with diabetes in the region remains underdocumented. This review aimed to synthesize the available literature to identify the prevalence and predictors of TM use among persons with diabetes in Africa. A systematic search was conducted across multiple databases, including MEDLINE, Embase, CINAHL, and AMED, covering studies published from 2000 to April 2023. Of 1560 records identified, 24 articles met the inclusion criteria. The prevalence of TM use varied significantly, ranging from 12.4% to 77.1%, with a median prevalence of 50%. TM was commonly used concurrently with conventional medicine (CM) (35.4–88.4%), with a majority (63.8–91.3%) not disclosing TM use to healthcare providers. Female gender, long diabetes duration, use of oral antiglycaemic medication and family history of diabetes emerged as the most common factors that predicted the use of TM. This review highlights the widespread use of TM among individuals with diabetes in Africa, often in conjunction with CM. The high prevalence of undisclosed TM use emphasizes the urgent need for healthcare providers to actively inquire about TM use during clinical consultations to address potential herb–drug interactions and adverse effects.

Emmanuel Ekpor Emmanuel ekpor

University life in an era of disruption of covid-19: a meta-methods and multi-mixed methods research study of perceptions and attitudes of south african students

On 18 March 2020, all South African universities and colleges were closed due to the COVID-19 virus. By early April, 10 universities announced that they were planning to resume teaching and learning online, including the University of the Witwatersrand (i.e., Wits University), Johannesburg, which is the joint highest ranked university in Africa. Therefore, the purpose of this editorial was to examine the perceptions and attitudes of these students regarding online learning in an era of disruption of COVID-19, uniquely using both multi-mixed methods research approaches (i.e., involving the partial integration of multiple methods research approaches and mixed methods research approaches) and meta-methods study approaches (i.e., involving the full[er] integration of multiple methods research approaches and mixed methods research approaches). A total of 4,419 Wits University students completed an online survey. A principal components analysis of one of survey’s scales, namely, the Attitude of Students Towards COVID-19 and its Impact on Higher Education scale, revealed 2 subscales, namely, Students’ Self-regulation Towards COVID-19-Based Higher Education and Attitudes Toward Teaching, Learning, and Assessment in COVID-19-Based Higher Education. Nonparametric analyses revealed that scores on these measures discriminated gender, age group, level of student (i.e., undergraduate vs. postgraduate), locality status (i.e., local vs. international student), and registration status (i.e., full-time vs. part-time). A multiple analysis of the open-ended responses by the VOSviewer 1.6.14 text mining software program led to the identification of 6 metathemes. Similarly, WordStat 8.0.29 topic modeling yielded 5 metathemes that mapped onto VOSviewer’s 6 metathemes, indicating triangulation of findings. A sentiment analysis revealed negative sentiments that identified not only the biggest challenges for students but also the characteristics of students who experience these challenges. Finally, a cluster analysis, combined with chi-square analyses, led to the identification of 4 clusters of students who differed with respect to their attitudes and online experiences. Implications of these findings are discussed.

Dr Emmanuel Ojo Dr emmanuel ojo

Home administration of oral medications to children: parental challenges and practices in libya

Administering medication to children at home presents substantial challenges for caregivers. Errors in dosage, timing, or administration method could be harmful. A key contributor to such errors is inadequate knowledge of pediatric medication. The objective of this study was to explore how parents in Libya administer oral medications to their children and the self-care therapies they use for them. A cross-sectional study was conducted using an online self-designed questionnaire consisting of yes/no and multiple-response questions. The sample size was 523 parents with valid questionnaires. Inclusion criteria were being a parent of children aged six months to 10 years and consent to participate. The data were analyzed by the Chi-square test was employed to examine associations between demographic characteristics and parental behaviors and techniques of medication administration. One-third of parents used inappropriate tools to administer liquid medications to their children. When children resisted medication, 49.3% of parents insisted on administering it, 10.7% mixed it with milk or other drink, 5.2% mixed it with food, and 9.2% dissolved solid forms in water or another drink. Additionally, 9.4% of parents admitted to giving doses higher than prescribed, trying to achieve rapid recovery. Furthermore, 82.0% of the parents engaged in self-medication of children, mostly with antipyretics (86.4%) but also with antibiotics (2.5%). We concluded that knowledge of the correct practices for administering oral medication to children was inadequate. It is suggested to develop educational programs for parents on correct practices.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

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