An experiment was carried out during kharif 2017 at Zonal Research Station, Chianki using sixteen promising genotypes of okra with three replications in randomized block design. Observations on ten important quantitative characters were recorded. Analyzed data revealed that all characters showed significant effect. The genotype Ajeet-121 gave significantly highest yield with the yield of 135.12 q/ha followed by NS-862 and Super green with the yield of 134.75 q/ha and 134.02 q/ha, respectively. Average fruit weight (15.33 g) and yield of fruits per plant (245.67 g/plant) were recorded significantly highest in the genotype Ajeet-121. On the basis of these observations, it may be concluded that the genotype Ajeet-121 was found most suitable okra genotype for kharif cultivation in the western plateau region (sub zone-V) of Jharkhand.

International journal of agricultural and applied sciences (ijaas)

Various quality control tests are employed for solid dosage forms such as uniformity, dissolution and drug contents in order to assess their pharmaceutical equivalence. The objective of the current study was to assess and contrast five distinct metformin hydrochloride brands that are offered for sale in the Libyan market. The physicochemical equivalence of the five brands of metformin hydrochloride tablets (500 mg) were determined through the evaluation of official and non-official standards according to the USP including uniformity of weight, friability, hardness, dissolution rate and drug content. All the examined brands available in the Libyan market passed the official weight variation, friability, dissolution and disintegration tests and were equivalent. The friability test was found within the specified limit. All the formulations were disintegrated within 09 - 15 min. The tested brands were non-equivalent to the innovator Glucophage® according to their dissolution evaluation. The percentage content of the active ingredient of five brands of metformin tablets showed values within the monograph specifications (95% - 105%). In conclusion, all the five brands available in the Libyan market which were evaluated in this study cannot be substituted with the innovator product in clinical practice.

Mediterranean journal of pharmacy and pharmaceutical sciences

Vitamin E is extensively available in the natural world and is produced by prototrophs such as plants, algae, and blue-green algae. Vitamin E is used as a dietary supplement, an antioxidant food stabilizer, a pharmaceutical additive, and a preservative in livestock feed. Several types of vitamin E can be differentiated by the position and number of the methyl functional group, and each form has a unique biological role. The function of antioxidants such as vitamin E is to defend cells from the effects of oxidative stress. Vitamin E is a free radical scavenger converted to vitamin E radical, then converted back to vitamin E by ascorbic acid. Vitamin E was discovered by Evans and Bishop in 1922; it has proved to be an effective nutrient for reproduction. It is also possible for vitamin E to act by a mechanism not directly linked to the inhibition of oxidation. Such non-antioxidant actions of vitamin E may result from gene regulation and specific cell signalling. The function of vitamin E in cellular signalling, especially its biological impact, is undoubtedly an imperative subject for future studies. The explicit roles of the several isomers and esters of vitamin E analogues should also be the subjects of future studies.

Dr. salman ahmed

Patent foramen ovale (PFO) is an embryonic interatrialdefect potentially associated withischemic cerebralstrokes. One option is the occlusion of the atrial shunt byendovascular means. This procedure is recommendedfor patients with a history of cryptogenic strokes.Patent foramen ovales (PFOs) are common in the general population (prevalence 20-30%) and do not constitute a pathology in their own terms. Nevertheless, a association has been established between the occurrence of certain cryptogenic ischemic strokes and the presence of a PFO. The risk appears higher when septal patency is associated with atrial septal aneurysm (ASA). The aim of this presentation is to study the association between the PFO and the occurrence of ischemic stroke, and the benefits of its closure.

Kalkoul hamza

Corporate social responsibility (CSR) is a self-regulating business model that helps a company be socially accountable—to itself, its stakeholders, and the public. Reliance Foundation (RF) is a not-for-profit organization established by RIL to bring about changes in Indian society seamlessly. CSR is for the community, it is equally valuable for a company. CSR activities can help forge a stronger bond between employees and corporations, boost morale and help both employees and employers feel more connected with the world.

Vidya bhat

The present review shares updated data on the botany, distribution, traditional medicinal uses, phytochemistry and pharmacology of Macrotyloma uniflorum (Lam.) Verdc. All provided information was obtained through Google Scholar, Pubmed, SciFinder, Scirus, Web of Science and a library search.

Dr. salman ahmed

Background: Intracerebral hemorrhage (ICH) has not been widely investigated in young adults. This study aims to describe the risk factors of ICH with a focus on the possible effect of non-modifiable risk factors, such as genetic factors, to assess the ICH outcomes, and to identify the prognostic factors after ICH among young adult patients. Methods: This prospective and observational study was conducted at two hospitals at Hamad Medical Corporation, Qatar, namely Hamad General Hospital and Alkhor Hospital. The study included young patients (16–45 years old) admitted with ICH between January 1, 2015, and December 31, 2018. Results: We examined 238 consecutive young patients with ICH consisting of 212 (89.1%) males and 26 (10.9%) females. The mean age was 37.8±6.23 years. The most common risk factor found in 187 (78.6%) patients was hypertension (HTN), while 19 (8.0%) patients had no obvious risk factors (cryptogenic). The primary site of bleeding was cerebral cortex (lobar) in 107 (44.96%) patients and then basal ganglia in 97 (40.76%) patients. The in-hospital mortality was 19 (8.0%); the National Institutes of Health Stroke Scale >14 on admission (adjusted OR=2.06; 95% CI=1.448–2.938; p<0.001), Barthel index score ≤40 on admission (adjusted OR=1.09; 95% CI=1.015–1.178; p=0.019), and HTN (adjusted OR=0.075; 95% CI=0.008–0.724; p=0.025) were found to be independent predictors of in-hospital mortality by multivariate analysis. A 1-year follow-up showed mortality in 7 (3.2%) patients and no new events in 139 (63.8%) cases. Conclusion: HTN, smoking, and excessive alcohol consumption are important modifiable risk factors for ICH among young patients in Qatar, requiring early identification and treatment to prevent this dangerous type of stroke. In addition, we recommend conducting further studies focusing on the genetic risk factors of ICH among young adults, particularly those with cryptogenic ICH, to identify whether genetic risk factors are involved.

Karishma

The main aim of rehabilitation is vocational independence and community integration. Rehabilitation is complete with the person being a productive member within the community. But this is quite a challenging task as can be vouched by any of the professionals working in this field. What are the barriers and facilitators towards employment or return to work in case of persons living with mental illness? Literature shows that multiple factors are governing the ability to take up gainful employment. Most of this literature is about the western world where the social fabric is more supportive of individual autonomy. India lags in its rehabilitation efforts for mental illness. There is still stigma and lack of awareness about mental illnesses. This increases the problem of unemployment within persons living with mental illness manifold. There are very few detailed investigations into the vocational status of persons with mental illness and almost negligent literature existing in the Indian context. Hence, the current review article tries to examine the factors prevailing in the Indian scenario that influences the employment status.

Gita

By January 2020, severe acute respiratory syndrome coronavirus-2 has spread internationally to a pandemic that mainly targets the respiratory system. The relevant infectious disease has been identified as coronavirus disease-2019 (COVID-19) by World Health Organization and declared as a global pandemic. In Libya, National Center for Disease Control reported the first case of coronavirus disease-2019 on 24th March, 2020. The authorities decided to close borders and activate designated treatment centers to deal with COVID-19 cases and contain the outbreak of SARS-COV-2. This study aimed to assess and evaluate the pharmaceutical situation of medications used in pharmacological management of hospitalized COVID-19 patients in Tripoli, Libya. Three WHO availability indicators were selected to be studied and reported. A comprehensive list of medicines used in the management of hospitalized COVID-19 patients was constructed after reviewing and comparing seven national and international pharmacological management protocols and guidelines for hospitalized COVID-19 patients. This comparison revealed that nearly 50 medications are intended for use in COVID-19 inpatient pharmacological management. They all agreed about the use of three medications, representing one from each main class. This list was used to cross check their availability at the chosen designated COVID-19 treatment center. This study proved that local treatment center’s protocol is more in line with international guidelines than the national treatment guideline. The later was issued on March 2020. The Libyan National Essential Medicines’ List contained 25 out of 50 medications of the comprehensive list based on the last update in April 2019. This study recommends that national treatment guidelines and National Essential Medicines’ list require updating. Not all medications used in COVID-19 inpatient management were available in local treatment centers, although, the Emergency Management Department of Ministry of Health in Libya is responsible for the supply of the required medical supplies and medications to the COVID-19 treatment centers.

Mediterranean journal of pharmacy and pharmaceutical sciences

The Cellular Manufacturing is adopted in batch type manufacturing industries nowadays for their production with increased productivity, less cost and time with effective control. The proposed optimization model is used to determine the cost of machine cells, i.e., machine duplication, part subcontract, inter intra cellular movements cost and cost of production associated with machine cell, such as machine reconfiguration and part inventory considering machine flexibility for various time periods. Initially, mathematical model is proposed to calculate machine cell cost with and without considering machine flexibility and then another lpp integer model is proposed to calculate the machine cell production and associated cost for the changes in time period, part type and volume considering machine flexibility. The manufacturing data in the incidence matrix and machine cell, part family data in the block diagonal form are given as input to the optimization programming language Cplex and the output are given for the two mathematical models. The data related to machine duplication, part subcontract, inter intra cellular movement; machine reconfiguration and part inventory are given. Two dimensional shop floor layouts are presented in rectilinear coordinates for all the problems for easy analysis of material movement length and shop floor area

S ramesh

A huge number of embedded devices offer their services to the end users in pervasive environments. Context-aware discovery is a rich and very dynamic system extensively applied for combining the different mobile devices, sensors, actuators and software functions. Existing knowledge-based system using the Common KADS (CKADS) system represent contextual information but algorithm are not effective in predicting the user behavior. Current Location-aware Private Service Discovery (LPSD) considers the discovery path for reducing the distributed topology and flooding operations. LPSD in pervasive environment is not effective in accurately locating the required service by searching method. To present an architecture principle for accurately predicting the user behavior in mobile-pervasive computing environment, Affluent Context Aware Systems based on the User Behavior (ACAS-UB) is proposed in this paper. ACAS-UB mechanism contains the class of mobile devices that can sense (i.e.,) search the physical pervasive environment. Affluent means effectively engaged mobile devices in ACAS-UB mechanism which uses the context information. The ACAS-UB context information contains the judgment of the similar users and also the response from the other users for improving the effectiveness in pervasive environment user behavior prediction. Master-slave concept is used in the ACAS-UB mechanism for the easy collection of response information from the different users. ACAS-UB mechanism construct the user profile initially from the context information, then performs the similarity measure and finally work is to predict the user behavior. ACAS-UB mechanism provides the hints which are necessary to explore different options, rather than just limiting the options in mobile-pervasive computing environment. ACASUB mechanism is experimented on the factors such as message overhead in pervasive environment, scalability and approximately 10 % lesser processing time.

Dr h shaheen

There is an upsurge in gestational diabetes mellitus with many devastating consequences for the mother and developing fetus. Insulin therapy remains a mainstay. However, insulin is expensive and comes with the pain of multiple injections. Therefore, there is a need to explore commonly administered oral hypoglycemic agents to cater for the increasing gestational diabetes mellitus-associated neurological complications. This study assesses the effects of glibenclamide, metformin and insulin on the pups’ prefrontal cortex in diabetic pregnant rats. 35 sexually matured adult female rats weighing between 120 g and 160 g were used and assigned into five groups (A to E) of seven rats each group. Diabetes was induced by streptozotocin (45 mg/kg and 35 mg/kg; ip). Hyperglycemic rats were treated with insulin (1.0 UI daily), metformin (200 mg/kg/day) and glibenclamide (0.6 mg/kg/day). Body weight and blood glucose levels were evaluated. Rats were sacrificed at 18-day gestation, the pups were harvested, and their brains were processed for tissue oxidative stress markers and various histological examinations. Glibenclamide and metformin caused a significant blood glucose reduction at 37.9% and 40.7%, respectively, compared to the insulin group (33.09%). There was no significant difference in the body-organ ratio in rats treated with metformin when compared to rats treated with insulin. Metformin and glibenclamide had a significant increase in tissue glutathione reductase and a decrease in malondialdehyde compared with insulin and diabetic control groups. The pups’ prefrontal cortex showed degenerated neuronal cells in the diabetic control animals. The diabetic rats treated with metformin and glibenclamide showed improved pyramidal neurons compared with diabetic and insulin groups. This study suggests that metformin and glibenclamide glycemic control may prevent and improve antioxidant enzymes and reverse some neurotoxic effects caused by streptozotocin-induced diabetes in rats.

Mediterranean journal of pharmacy and pharmaceutical sciences

As the demand for renewable energy continues to rise, it becomes crucial to discover effective ways to enhance grid-connected photovoltaic (PV) battery energy storage systems. The Institute of Petroleum Studies (IPS) complex at the University of Port Harcourt in Rivers State, Nigeria, embarked on a quest to determine the optimal approach for optimizing their PV battery energy storage system. This research aimed to fulfill this need by employing a diverse research methodology, incorporating the innovative MOALO theory. To begin with, the research gathered primary and secondary data to construct models for the power grid, solarPV, and battery. Furthermore, it meticulously analyzed the load profile of the IPS complex, at the University of Port Harcourt. Leveraging the power of the MOALO theory.The researchers accurately sized the system and evaluated the potential outcomes of simultaneously interconnecting all loads. To gauge the system's performance, there was a calculation of various parameters such as economics, random walk, boundary conditioning, entrapping ants, and ant trap development. Remarkably, the outcome showed that the fitness responses between the two trial runs, facilitated by the integration of MOALO, were strikingly similar, revealing a typical concaveconnected shape, which is characteristic of a multi-objective solver. The optimal multi-objective cost implication of the system was estimated to be around 4,300 USD, with a power mismatch performance of approximately -1.7819e+09. Based on these compelling findings, the study concluded that MOALO serves as an impressive optimization tool capable of minimizing power mismatches and optimizing costs. Moreover, it recommended the generation of excess power as a means to achieve sustainability.

Fxintegrity publishing

We present a series of large-eddy simulations to systematically investigate the impact of debris accumulation on the hydrodynamics and power production of a utility-scale marine hydrokinetic (MHK) turbine under various debris loads lodged on the upstream face of the turbine tower. The turbine blades are modeled using turbine resolving, actuator line, and actuator surface methods. Moreover, the influence of debris on the flow field is captured by directly resolving individual logs and employing a novel debris model. Analyzing the hydrodynamics effects of various debris accumulations, we show that an increase in the density of debris accumulation leads to more flow bypassing beneath the turbine blade. This, in turn, reduces the flow momentum that reaches the MHK blades at the lower depths, inducing significant fluctuation in power production. Further, it is shown that debris-induced turbulent fluctuations contribute to significant variability in the MHK turbine’s power production.

Hossein seyedzadeh

Bank sector crisis across the globe is largely blamed on the joint effort of bank liquidity and bank credit risks. And so, the twin concepts of liquidity and credit risks have come under keen academic scrutiny, especially in investment finance. Contributing to the extant literature on these developments, secondary data were obtained from the websites of nine banks in Ghana, spanning 2008 to 2018, to determine how liquidity and credit risks separately and interactively impact bank stability in Ghana. Analysis of data was done using a panel regression through the fixed effects model after running the Hausman Test. The study confirms an inverse liquidity risk-bank stability relationship, emphasising the need to channel idle funds into interest-earning securities to consolidate bank profits. Although a further revelation suggests an insignificant negative relationship between credit risk and bank stability, it re-echoes the need to implement policy recommendations made by the Banks and Specialised Deposit-Taking Institutions’ ACT 2016 (ACT 930), section 62 of Ghana, on the threshold to lend funds to clients. The bank-size-stability relationship was positive. Increasing bank size through establishing more branches nationwide is encouraged but to a precautionary level since banks tend to suffer diseconomies of large scale operations due to unregulated expansion. There is the need to observe the Basel III provisions on maintenance of a 30-day optimum liquidity threshold of up to 100% and above. Besides, banks should tighten up their credit requirements and also ensure loan repayments history is monitored to benefit clients who are in good standing.

Juabin matey

India is a diverse land with a population of approximately 1.3 billion,1 placing India at the second position in the world in terms of population. Among these, Seventh-day Adventists' existence, as per the statistics of 2019, is 1.14 million.2 India is a richly diverse community, inclosing a diverse range of ethnic groups, each, not just different, but on occasion quite the opposite. The present population of the country can be divided among four racial groups: Negritos, proto-Australoid, the Mongoloids, and the Mediterranean.34 These racial groups today majorly fall in different ethnic groups based on their linguistic classifications. They are Indo-Aryan (78.05 percent), Dravidian (19.64 percent), and the remaining 2.31 percent of the population segregated among Austroasiatic (Mon-Khmer), Sino-Tibetan, and Tai-Kadai.5 This ethnic diversity can be easily seen within the Adventist church too.

Santosh kumar

Capsicum has been an essential part of the diet for centuries and has been widely used traditionally for ailments. The objective of the present analysis was to determine the diuretic and antidiarrheal potentials of four variations of Capsicum annum L. fruits available in the local market of Karachi, Pakistan. It belongs to the family Solanaceae, and extracts were prepared in 95% ethanol and given in 200 and 400mg/kg doses. The activity correlated with commonly used diuretics and anti-diarrheal, reinforcing its conventional use. To confirm its activity, fruit extracts were evaluated for anti-diarrheal properties in castor-oil-induced diarrhoea. The diuretic activity of the 95% ethanolic extracts of Capsicum annum L. was assessed based on diuresis of 24 hr. collected through a metabolic cage. Urinary excretion of water and electrolytes (Na+ and K+) is significantly increased by the standard diuretic drug furosemide, which is comparable with the extract. The anti-diarrheal effects of 95% ethanolic extracts of Capsicum annum L. were examined by castor oil-induced diarrhoea. All varieties of Capsicum annum L. significantly inhibited the number of defecations.

Dr. salman ahmed

Aim: Murraya koenigii is a widely used plant both as a potential medicinal agent and also for common cooking purposes. Aim of this present study was to determine the antimicrobial activity of Murraya koenigii leaf extracts on Staphylococcus aureus and Escherichia coli. Study Design: Screening and isolation of pathogenic bacterial strains from contaminated water. Preparation of Murraya koenigii leaf extracts using petroleum ether, acetone and ethyl acetate by using serial extraction method with Soxhlet apparatus. Place and Duration of Study: Department of microbiology, Agro biotec research centre Ltd, Poovanthuruthu, Kottayam, Kerala, India, between 2014 January to 2014 May. Methodology: Staphylococcus aureus and Escherichia coli were the bacterial strains used in this study. Morphological and biochemical analysis of microorganisms were conducted to identify the strains. Leaf extracts (petroleum ether, acetone and ethyl acetate) of Murraya koenigii were screened using MHA disc diffusion methods. Results: Various concentration of plant extracts were used to check its activity against isolated pathogens. Acetone extract of curry leaves exhibit maximum zone of inhibition against Staphylococcus aureus and petroleum ether extracts shown maximum inhibition against Escherichia coli.

Dr. hemand aravind | sr.research scientist | abtec ltd

The present study focused on analysing the impact of ‘Make in India’ campaign on FDI inflows in country. The research period is divided in two parts one is pre ‘MII’ & another is post ‘MII’ period. The analysis of ‘Make in India’ campaign is done to identify the scope of the campaign & methodology of working of various allied departments monitoring campaign. The present research work also attempted to take overview of various policy reforms initiated by Government of India to promote the FDI as well domestic investment in 25 sectors shortlisted under MII. The FDI inflows statistics reveals that, the post MII period is showing the highest growth in FDI equity inflows as compare to same period i.e. 2009- 2014. The MII initiative is one of the reason for the jump in FDI inflows. The overview of policy reforms shows that GOI through DIPP attempted to open almost all sectors for 100% FDI through automatic route. Government has provided multiple incentives for Foreign Investors to establish their manufacturing facilities in country but very negligible response has been seen in the nature of FDI equity inflows in the same period. Further results of study reveals that multiple ‘MOU’s have been signed by States & Central Governments, but they yet not converted in actual investments. The major reasons behind the same is lack of SWOT analysis through Governments before inviting the foreign investors. As well lack of basic infrastructure, land, lack of skilled manpower, cheap & un interrupted power supply to MIDC’s & SEZ’s is yet not successfully provided, lower rankings in Ease Of Doing Business (EODB), Global Manufacturing Competitiveness Index (GMCI) is also cause of concern & tumbling block in the success of MII mission..

Anshuman vijay magar

The current study was conducted to determine the insoluble, soluble, and total dietary fiber content of Macrotyloma uniflorum (Lam.) Verdc., Phaseolus lunatus Linn., and Phaseolus vulgaris Linn., legume flours, using AOAC enzymatic-gravimetric analysis. The results showed that M. uniflorum, P. lunatus, and P. vulgaris legume flours contained 155.91, 120.01, and 90.80 mg/g insoluble dietary fiber, respectively. At the same time, soluble dietary fiber was not found in any tested sample.

Dr. salman ahmed