This mathematical model forms machine cells, optimises the costs of unassigned machines and components, and designs the shop floor cell layout to have minimal movement of materials. The complete similarity measure algorithm forms machine cells and part families in a refined form. Later, exceptional elements are eliminated in the optimisation model by using machine duplication and sub-contracting of parts. Then the shop floor layout is designed to have optimised material movements between and within cells. An evaluation of the cell formation algorithm’ performance is done on the benchmark problems of various batch sizes to reveal the process’s capability compared with other similar methods. The data of machining times are acquired and tabulated in a part incidence matrix, which is used as input for the algorithm. The results from the linear programming optimisation model are that costs are saved, machines are duplicated, parts are sub-contracted, and there are inter- and intra-cellular movements. Finally, the output of the inbound facility design is the floor layout, which has machine cell clusters within the optimised floor area.

S ramesh

In this intelligent transportation systems era, traffic congestion analysis in terms of vehicle detection followed by tracking their speed is gaining tremendous attention due to its complicated intrinsic ingredients. Specifically, in the existing literature, vehicle detection on highway roads are studied extensively while, to the best of our knowledge the identification and tracking of heavy-construction vehicles such as rollers are not yet fully explored. More specifically, heavy- construction vehicles such as road rollers, trenchers and bulldozers significantly aggravate the congestion in urban roads during peak hours because of their deadly slow movement rates accompanied by their occupation of majority of road portions. Due to these reasons, promising frameworks are very much important, which can identify the heavy-construction vehicles moving in urban traffic-prone roads so that appropriate congestion evaluation strategies can be adopted to monitor traffic situations. To solve these issues, this article proposes a new deep-learning based detection framework, which employs Single Shot Detector (SSD)-based object detection system consisting of CNNs. The experimental evaluations extensively carried out on three different datasets including the benchmark ones MIO-TCD localization dataset, clearly demonstrate the enhanced performance of the proposed detection framework in terms of confidence scores and time efficiency when compared to the existing techniques.

Sreelatha r

Abstract In every hospital, Casualty department deals with the emergency cases. These emergency cases also includes medicolegal cases like road traffic accidents, Poisoning, assaults are dealt in the casualty and detailed MLC report is made here after giving the proper primary treatment and life saving measures. The police is informed about MLC as early as possible. Important preventive measures like drawing public attention and awareness towards traumatic casualties can help in the prevention or management of unnatural (medicolegal cases). Considering the importance of above points, a one year retrospective study from 1st March 2018 to 31st March 2019 was conducted in the Casualty department of Tertiary Care Centre.

Dr. avinash harishchandra waghmode

Background: In dental practice, local anesthesia plays a very important role as it makes the patient more comfortable during his or her procedures. Nevertheless, difficulty in getting adequate anesthesia is still common because of several reasons such as the differences in anatomy, psychological considerations as well as technique related problems. The research paper will identify the knowledge, attitudes and practices (KAP) of dental professionals in relation to local anesthetic use and subsequent improvement of pain management in dentistry by establishing areas of weaknesses and suggesting means to address them. Methods: A cross-sectional survey of 150 dental practitioners comprising general dentists, dental surgeons as well as specialists was carried out to determine knowledge, attitudes and practices of dental practitioners with regard to local anesthesia. The questionnaire was made to gauge the knowledge of the respondents with regard to anesthetic agent, effects of psychological factors, and how the respondents approach the issue of anesthesia failure in their practice. Analysis was done based on descriptive statistics to give an insight into the common practices and areas of concern. Results: The survey showed that 85 percent of respondents used Lidocaine as their choice of anesthetic, 60 percent of them reported anatomical differences as the major factor of anesthesia efficacy and 85 percent of the respondents reported the critical role of patient anxiety. On the issue of confidence in administering local anesthesia, 40 percent had high confidence and 50 percent had some incidences of poor anesthesia. In case of the failure in anesthesia, 60 percent of practitioners chose to administer higher dosage instead of sending patients to experts. Conclusion: Although the majority of dental practitioners have a good grasp of the knowledge and confidence in the administration of the local anesthesia, there are some areas where improvements can be made, especially when addressing the psychological factors and communicating with patients. Patient-centered care methods and additional training are critical to maximising the efficacy of anesthesia. Keywords: Local anesthesia, Dental practitioners, Knowledge, Patient anxiety, Anesthesia failure.

Journal of scientific innovations in anesthesiology

Using off-label drugs in obstetric-gynecology patients requires caution because of the high risk of pregnancy. Although there is still debate, data profiling its use in clinical practice is lacking. This study aims to observe the use of off-label drugs in obstetrics and gynecology patients in private hospitals, especially the pill Misoprostol. This study used a descriptive observational approach to hospital medical record data. Retrieval of research data retrospectively at Bunda General Hospital (X Hospital) for July 2017 – December 2017 and Sinar Kasih Hospital (Y Hospital) for January 2018 – December 2018. The number of samples was determined using the Slovin formula, with a systematic random sampling technique at X Hospital and total sampling at Y Hospital. The samples were 220 RM at X 130 Hospital and Y 90 Hospital. The research was conducted in the period January 2019 - March 2019. The results were analyzed univariately using several related references. The results showed 26.92% of misoprostol off-label use in X Hospital and 4% in Y Hospital. The off-label drug found was Misoprostol which belongs to the category of off-label indications (Missed Abortion, Incomplete Abortion, Blighted Ovum, and Induction of labor in cases of Serotinus, KPD, and IUFD), off-label doses (50 µg, 100 µg, and 400 µg), and off-label routes of administration (sublingual and vaginal). ​

Much ilham novalisa aji wibowo

The goal of the present study was to investigate the molecular mechanisms that underlie heart andskeletal muscle damage in male Wistar rats weighing 200–250 g in response to a 3-h exposure to 180 mm Hg(5% O2) in the model of severe hypobaric hypoxia. It has been demonstrated that the level of the cardiac bio-marker troponin I in the blood plasma of rats exposed to severe hypobaric hypoxia for 3 h increased signifi-cantly compared to the control group, indicating myocardial injury. At the same time, the administration ofthe HIF-1α transcription factor inhibitor did not affect the plasma level of troponin I. In contrast, the releaseof the non-specific biomarker myoglobin into the bloodstream did not increase in response to hypoxia com-pared to the control animals. In addition, 24 h after the exposure to severe hypobaric hypoxia the serum myo-globin level was significantly lower in animals administered with the HIF-1α inhibitor topotecan than in ratsthat did not receive topotecan. Therefore, it may be assumed that the inhibition of the HIF-1α transcriptionfactor 10 min before exposure to severe hypobaric hypoxia reduces skeletal muscle damage. The mechanismsthat affect the adaptation of heart and skeletal muscles to hypoxia are discussed.

Даниил Федоров

In today's globalized world, the role of foreign direct investment (FDI) in shaping higher education cannot be overstated. This paper explores the multifaceted impact of FDI on higher education institutions worldwide, delving into its influence on academic programs, research endeavors, institutional infrastructure, and student experiences. Drawing upon a comprehensive review of scholarly literature, policy documents, and case studies, this paper elucidates the ways in which FDI contributes to the expansion and transformation of higher education systems across the globe. The analysis begins by examining the motivations driving foreign investors to engage with higher education, including economic imperatives, strategic partnerships, and knowledge transfer objectives. It then explores the diverse forms that FDI takes in the higher education sector, ranging from institutional partnerships and joint ventures to the establishment of branch campuses and research collaborations. By analyzing specific examples from different regions, this paper illustrates how FDI shapes the academic landscape, fosters innovation, and enhances internationalization efforts within higher education institutions.

Dr gedam kamalakar

Inlet valve in an engine tends to be subjected to immense thermal loads besides chemical corrosion. Opening and closing of inlet valve practically could be in the order of 2000 times per 1.6 km. In the mean time of engine working cycle, seat insert of the inlet valve is the surface, against which an intake valve seats. Conventional engine valves are provided with a curved angle for its seating position, but for this study, the same is proposed to be positioned at a tapered angle. This tapered position as converted into radius in order to permit rich air at the inlet and reduce exhaust emission. This study is to investigate the nature of the future redesigned Scooping valve for a 1.25L 4-cylinder Petrol engine with VTVT (Variable Timing and Valve Train) under combined mechanical and thermal loading cycle by feeding the input conditions for this study after NX-CAD modelling in ANSYS 10.0 software and the numerical results thus obtained are recorded for future valve design considerations.

Boopathy govindarajan

In Libya, mothers commonly use natural products for their infants. The purpose of this survey was to evaluate the level of awareness of mothers using natural products for their infants, a validated questionnaire-based survey was distributed for mothers in several hospitals, the selected random group included 152 mothers of infants aged from day one birth to one year old, an analysis of the data revealed that 68% of mothers were using natural products and the most predominant age was between 20 - 30 years, 63% were living in Tripoli and 52% were undergraduate level of education. Further statistical analysis was revealed a significant difference for measuring the degree of awareness of all the natural products combined together (p = 0.001) and a similar degree of significant difference to the degree of awareness of each natural product alone (p = 0.001). A correlation coefficient test by Spearman was preformed to evaluate if there is any association between participants’ demographic data and the question which measures the level of mothers’ awareness. The results showed that mothers have no awareness on how to use these natural products and no correlation between the participants’ demographic data and the way the mothers use these natural products, except between the fennel and the education level (p = 0.033, p < 0.05, respectively). In conclusion, mothers have no awareness on how to use natural products, an appropriate attention by health care providers should be given to nursing mothers for herbal use.

Mediterranean journal of pharmacy and pharmaceutical sciences

Abstract Indian telecom industry has started growing rapidly since 1990 because of market liberalization. It has become one of the fastest growing telecom markets since then. Operating performance of a firm is depending upon certain key financial factors viz., turnover, profit, asset utilization etc. and the variables which are found in profit and loss account and balance sheet of a firm have a direct or indirect relation with each other. Financial performance of the firms can be analyzed by establishing a close relationship between the variables, in terms of liquidity, profitability, viability and sustainability. By establishing a close relationship between the variables, a firm can analyze its financial performance in terms of liquidity, profitability, viability and sustainability. Ratios and the statistical tool of ANOVA are normally used to identify the financial health of the firms and financial performances of the firms are measured accordingly. So the present study concentrates on empirical approach towards measuring deals with financial performance of the telecommunication companies.

Dr. jeyalakshmi p

Background: There is a lack of adequate data about the prevalence and types of tuberculosis (TB) disease in Hadramout Al-Sahel, Yemen. Hence, this study aimed to investigate the prevalence, types, and outcomes of TB disease in Hadramout Al-Sahel, Yemen. Materials and Methods: This cross-sectional study was conducted at the National TB Program (NTP) center in the city of Al Mukalla, Hadramout, Yemen. The study enrolled TB patients from different districts of Hadramout Al-Sahel who had registered at the NTP center between January 1 and December 31, 2021. Results: A total of 127 new active TB cases were recruited, including 102 (80.3%) with pulmonary TB (PTB) and 25 (19.7%) with extra PTB (EPTB). The overall prevalence of TB disease in 2021 was 12.7 new TB cases per 100,000 population, while the median age of the study population was 38 years. The majority of cases (23.6%) belonged to the age group of 35–44 years. There were 85 (66.9%) males, and most patients (74; 58.3%) were identified in Al Mukalla City. EPTB was detected in 25 (19.7%) patients, with pleural effusion being the most frequent manifestation, found in 12 (48.0%) patients. All patients received 4-agent anti-TB therapies; 99 (77.9%) patients received anti-TB therapy for 6 months; 9 (7.1%) patients received anti-TB therapy for 9–12 months; 8 (6.3%) patients died during treatment; and 11 (8.7%) patients were lost during follow-up. The majority of patients (108; 85%) were cured on completion of treatment. Conclusion: The prevalence of TB in Hadramout Al -Sahel was 12.7 cases per 100,000 population. Males were affected more than females; the pleura was the most commonly affected extrapulmonary site; and 85% of cases were cured. The results indicated the need to support the Al Mukalla NTP center, by providing more resources for improved TB reporting and for conduct of surveillance to detect new TB cases among high risk groups. Health authorities are also urged to provide state hospitals with the equipment needed for TB diagnosis.

Karishma

Breast cancer commonly metastasizes to the bones, liver, lungs, and brain. However, metastasis to endocrine glands, particularly the adrenal and pituitary glands, is rare. We report the case of a 54-year-old woman with hormone receptor–positive, HER2-negative invasive ductal carcinoma of the right breast who initially showed a favorable response to standard therapy. Surveillance imaging in late 2022 revealed a left adrenal mass, subsequently confirmed as metastatic breast carcinoma. Following laparoscopic adrenalectomy, she developed primary adrenal insufficiency. By mid-2023, she presented with pituitary metastases, resulting in hypopituitarism, diabetes insipidus, and severe visual impairment. Despite targeted radiosurgery, her disease progressed rapidly, and she died in December 2024. This case illustrates an unusual metastatic pattern involving both the adrenal and pituitary glands and demonstrates the potential for aggressive clinical behavior even in hormone receptor–positive breast cancer. Clinicians should maintain a high index of suspicion for atypical metastatic sites to ensure timely diagnosis and optimize palliative care strategies.

Karishma

Pengembangan budaya keagamaan di sekolah merupakan suatu kewajiban yang harus dilaksanakan oleh sekolah dengan mendesain program pendidikan agama islam yang mengarah pada pengembangan budaya keagamaan. Fokus penelitian ini adalah Bagaimana perencanaan pengembangan program pembelajaran Pendidikan Agama Islam dalam meningkatkan budaya keagamaan di SDN Bletok Bungatan Situbondo? Bagaimana pelaksanaan pengembangan program pembelajaran Pendidikan Agama Islam dalam meningkatkan budaya keagamaan di SDN Bletok Bungatan Situbondo? dan Bagaimana pengawasan pengembangan program pembelajaran Pendidikan Agama Islam dalam meningkatkan budaya keagamaan di SDN Bletok Bungatan Situbondo? Penelitian ini menggunakan pendekatan deskriptif analisis, jenis studi kasus. Teknik pengumpulan data menggunakan wawancara, observasi, dan dokumentasi. Analisis data menggunakan model interaktif dan keabsahan data menggunakan triangulasi sumber. Hasil dari penelitian ini menunjukkan: 1) Perencanaan pengembangan program pembelajaran pendidikan agama islam dalam meningkatkan budaya keagamaan di SDN Bletok Bungatan Situbondo, yaitu: penyusunan buku pintar, Penugasan anggota membuat rancangan kegiatan, nilai-nilai karakter prioritas utama, rencana strategis pendekatan botton up, perencanaan pengembangan budaya keagamaan oleh tim agama. 2) Pelaksanaan pengembangan program pembelajaran pendidikan agama islam dalam meningkatkan budaya keagamaan di SDN Bletok Bungatan Situbondo, yaitu: Roling tanggung jawab job deskription pengembangan budaya, Quality Insurence (Jaminan Mutu) pembiasaan keagamaan, Model uswah guru, pelaksanaan Budaya keagamaan. 3) Pengawasan pengembangan program pembelajaran pendidikan agama islam dalam meningkatkan budaya keagamaan di SDN Bletok Bungatan Situbondo, yaitu: pengawasan internal kinerja anggota dan eksternal melalui pengguna layanan siswa dan orang tua, evaluasi supervisor sekolah terhadap kinerja anggota, anak berkepribadian sesuai dengan nilai-nilai agama, monitoring oleh komponen sekolah dan tim agama, monitoring siswa, monitoring tingkah laku dan pembiasaan siswa, penetapan capaian dari Quality Insurence.

Educare: journal of primary education

The present study reveals that the enriched aerobic cultures of indigenous microbes can be used successfully for decolorizing dye effluents. Physico-chemical analysis of dye effluent revealed high load of pollution indicators. Textile dye effluent and contaminated soils were collected and analyzed for selection of suitable bacteria for dye degradation. The residual bacterial load was found to be in the range of 108 cfu/mL. Six bacterial strains viz., two species of Bacillus, two species of Klebsiella,, one species each of Planococcus and Micrococcus luteus were isolated. The best two dye degraders namely species of Planococcus and Bacillus were further optimized for the effect of carbon and nitrogen source, pH, temperature and percentage of inoculum. The optimized conditions for both the isolates of Planococcus sp. and Bacillus sp. were used in bio-decolorization studies of textile effluent. More than 50% of decolorization was achieved within 4 d of incubation. After 6 d of incubation, decolorization was achieved above 80%. The isolates Planococcus sp. and Bacillus sp. exhibited maximum decolorization ability at pH between 5-8 and temperature 37C. Moreover, 10% (v/v) inoculums, glucose and peptone as carbon and nitrogen sources were found to be the optimum for decolorization. Both the isolates showed highest decolorization percentage of Coractive Blue 3R dye effectively during optimization and more interestingly showed consistent decolorization of textile dye throughout the study.

Dr. saranya devi k

Human being has lot of virtual mask in their behaviour (mind or brain). By the way of probability study alone, be able to find a person’s loyalty through their emotions, stress of speech, way of expressions and so on. It is not a novel technique to this world. The judgement and the hearings are finalizing in accordance to passed parameters (questions, transparent as well hidden test) and the result. Artificial Neural Network (ANN) is one of the best methods meant for speech stress analysing based cheap lie detection for the loyalty test. To show the results, polygraph is a comprehensible demonstration oriented approach. These methods are already used by the insurance fraud investigations and police. Through an individual’s stress (stress percentage or else range) voice as well their emotions are able to detect the loyalty. Lie detection techniques require being extremely confidential and dynamic. For the reason that voice stress analysis (VSA) parameters have to be an encrypted for avoiding speech practise with testing tool. Here this paper, outlooks by using for predicting the liars through Speech VSA.

Dr h shaheen

The domestication of animals and cultivation of crops have been essential to human development throughout history, with the agricultural sector playing a pivotal role. Insufficient nutrition often leads to plant diseases, such as those affecting rice crops, resulting in yield losses of 20-40% of total production. These losses carry significant global economic consequences. Timely disease diagnosis is critical for implementing effective treatments and mitigating financial losses. However, despite technological advancements, rice disease diagnosis primarily depends on manual methods. In this study, we present a novel Self-Attention Network (SANET) based on the ResNet50 architecture, incorporating a kernel attention mechanism for accurate AI-assisted rice disease classification. We employ attention modules to extract contextual dependencies within images, focusing on essential features for disease identification. Using a publicly available rice disease dataset comprising four classes (three disease types and healthy leaves), we conducted cross-validated classification experiments to evaluate our proposed model. The results reveal that the attention-based mechanism effectively guides the Convolutional Neural Network (CNN) in learning valuable features, resulting in accurate image classification and reduced performance variation compared to state-of-the-art methods. Our SANET model achieved a test set accuracy of 98.71%, surpassing current leading models. These findings highlight the potential for widespread AI adoption in agricultural disease diagnosis and management, ultimately enhancing efficiency and effectiveness within the sector.

Mehdhar s. a. m. al-gaashani

Patients who are on regular hemodialysis and who have advanced renal failure but have not yet started on renal replacement therapy have a high risk of tendon rupture, although this is a rare situation. We reported a case of 55-year-old male patient who had been on regular hemodialysis for the past 10 years. He presented with a sudden onset of pain and swelling in the left posterior ankle while climbing stairs. Ultrasonography revealed a complete disruption of the Achilles tendon, which was surgically repaired. His medical history was remarkable for the right Achilles tendon rupture a year ago. Investigations revealed tertiary hyperparathyroidism with chronic metabolic acidosis and high β-2 macroglobulin. With surgical repair, physiotherapy, and parathyroidectomy, the patient regained full active mobility. This case emphasized the importance of high parathyroid hormone level, metabolic acidosis, and high β-2 macroglobulin in the pathogenesis of tendons ruptures.

Karishma

Background: Hospital acquired infections (HAIs) are infections that patients acquire while receiving treatments for other conditions. Studies have shown that stethoscopes and sphygmomanometers can act as potential sources of these infections in patients accessing treatment in healthcare facilities. This study aimed to increase awareness among health workers in Nigeria of the potentials of stethoscopes and sphygmomanometers to transmit HAIs. Methods: Moist swab sticks were used to collect samples from 38 randomly selected stethoscopes and sphygmomanometers from some departments of four district hospitals. Collected samples were cultured using standard microbiological techniques. In addition, self-designed questionnaire was used to assess the knowledge and practice of doctors and nurses on the roles of stethoscopes and sphygmomanometers in HAIs. Results: About 83.8% of the health workers demonstrated some awareness of the roles of stethoscopes and sphygmomanometers in HAIs. 42.5% cleaned their stethoscopes, while 5% their sphygmomanometers. Staphylococcus aureus, (65.9% of stethoscopes), proteus mirabilis, Pseudomonas aeruginosa (67.6% of sphygmomanometers), Streptococcus and Coliform species were isolated. There was no significant difference between the contamination of stethoscopes and sphygmomanometers by the isolates, except for Pseudomonas aeruginosa (t=3.49, p=0.04). Conclusions: Awareness did not match practice in cleaning the stethoscopes and sphygmomanometers in the four facilities. Staphylococcus aureus and Pseudomonas aeruginosa were the two most common organisms isolated with a significant difference (t=3.49, p=0.04) between stethoscopes and sphygmomanometers in isolation of Pseudomonas aeruginosa. To curb HAIs, health workers need to improve on their practice of cleaning stethoscopes and sphygmomanometers.

Emmanuel umegbolu

In this research study, the mechanical properties of several Polymer matrix composites are investigated. These composites are multi-phase materials in which reinforcing materials are properly mixed with a polymer matrix. More precisely, Nylon 6 reinforced with 5, 15 and 25 wt. % of silicon carbide (SiC) and Nylon 6 reinforced with 5, 15 and 25 wt. % of boron carbide (B4C), prepared by means of an injection moulding process at three different injection pressures are considered. Specific attention is paid to the tensile and impact strength of these composites. The Taguchi technique is used to optimize the process parameters such as reinforcement material, its percentage and the injection pressure. It is observed that the specimens 5% SiC with 80 MPa injection pressure display a better tensile strength and similarly the specimen 5% B4C with 90 MPa injection pressure have a superior impact strength.

Boopathy govindarajan

Diabetes mellitus is a common and chronic metabolic disorder. Uncontrolled diabetes mellitus leads to body organ damage if not treated properly. Educational intervention is necessary from health-care providers such as pharmacists to prevent or reduce organ damage and complications among the diabetic patients. Several studies have demonstrated the contribution of pharmacists in achieving a better control of diabetes mellitus. Thus, this study intended to assess the knowledge and practice regarding foot care among Libyan diabetic patients in Al-Bayda city. In addition, to determine the association between knowledge and practice regarding diabetic foot care with selected demographic variables. This is a cross sectional study conducted at Diabetes Center Aljabal Al akhdar in Al-Bayda between April and August, 2022. A total of 400 participants with diabetes were enrolled and interviewed by using a self-design questionnaire for knowledge and practice of foot care after taking verbal agreement. Data was analyzed by using SPSS software version 26.0. In this study, 191 subjects were male (47.8%) and 209 subjects (52.3%) were female. On the topic of foot care, 51.8% of the participants stated they did know how to perform correct foot hygiene and 33.5% stated that drying should consist of passing a towel between their toes. Female subjects statistically had more knowledge than male subjects on the right footwear and correct way of nail cutting (p < 0.01 and p < 0.001, respectively). In relation to practice, the frequency of patients with a good practice was 126 (31.5%) and with poor practice was 274 (68.5%). Evaluating the parameters dry, moisturize and nail cutting, women showed a significant difference in relation to men, with a high significance level in the three parameters. In conclusion, the knowledge and practice of foot care in Libyan patients with diabetes were poor. So, an educational program is recommended to improve the awareness of foot care. Diabetic patients should be provided information about self-care of their feet by health care providers such as pharmacists to prevent and delay onset of foot complications and improve the quality of life.

Mediterranean journal of pharmacy and pharmaceutical sciences